• Incomplete suppression of viral replication caused by insufficient drug levels, low adherence, compartmentation and individual pharmacogenetic characteristics of the patient are important factors influencing TDR. (rki.de)
  • However, the analysis of resistance pathways to new antiretroviral drugs is key to enhancing the understanding of future risks regarding viral failure and guaranteeing a successful treatment outcome for patients infected with HIV. (rki.de)
  • The first-in-class maturation inhibitor, PA-457, is a potent inhibitor of HIV-1 drug-resistant isolates and acts synergistically with approved HIV drugs in vitro. (wikipedia.org)
  • 2002), boosted by the so-called ARMD (accelerated resistance to multiple drugs) phenotype, which is itself drug induced. (blogspot.com)
  • Therefore, the German network of competence on viral hepatitis (Hep-Net) has revised guidelines on diagnosis and treatment og HBV incetion in cooperation with the national societies for Gastroenterology, Pathology, Virology, and Pediatric Gastroenterology. (tum.de)