The discoveries of uranium 237 and symmetric fission - from the archival papers of Nishina and Kimura.
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Shortly before the Second World War time, Nishina reported on a series of prominent nuclear physical and radiochemical studies in collaboration with Kimura. They artificially produced (231)Th, a member of the natural actinium series of nuclides, by bombarding thorium with fast neutrons. This resulted in the discovery of (237)U, a new isotope of uranium, by bombarding uranium with fast neutrons, and confirmed that (237)U disintegrates into element 93 with a mass number of 237. They also identified the isotopes of several middle-weighted elements produced by the symmetric fission of uranium. In this review article, the highlights of their work are briefly summarized along with some explanatory commentaries. (+info)
Open access part I: the movement, the issues, and the benefits.
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The advent of Open Access (OA) has changed the landscape of accessing digital information globally. OA offers valuable free, full-text, online resources for all health-related professionals, regardless of the practice setting. Because much scholarly information may now be accessed without charge, nurses worldwide can reach a higher level of information competency-a prime requirement for evidence-based practice. This article provides a brief account of the OA movement, introduces new terminology, discusses various publishing models, and elucidates issues surrounding the choice to publish in OA journals. Many stakeholders derive benefits from Open Access. Nursing must take action to participate in and promote the OA movement in order to derive the maximum gain for our science. (+info)
Report on emerging technologies for translational bioinformatics: a symposium on gene expression profiling for archival tissues.
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Labelling of cells of the mononuclear phagocyte system in routinely processed archival biopsy specimens with monoclonal antibody EBM/11.
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When first reported, EBM/11 reacted with mononuclear phagocyte system cells only in fresh frozen sections, but it has been shown to have similar cellular specificity in routine formalin fixed, paraffin wax embedded tissue. This was achieved by limited proteolysis with protease XIV before immunocytochemical staining. In archival biopsy specimens EBM/11 produced granular cytoplasmic staining of alveolar macrophages, Kupffer cells, tingible body macrophages and sinus histiocytes, cells of splenic cords, cortical and medullary macrophages of thymus; blood monocytes, peritoneal and mesothelial macrophages; bone marrow mononuclear cells, megakaryocytes and osteoclasts; lamina propria macrophages in the gastrointestinal tract, and connective tissue cells (presumptive macrophages) of thyroid, gall bladder, skin, pancreas, ovary, myometrium, endometrium, cervix, kidney, prostate, placenta, myocardium and breast. Unlike other anti-macrophage antibodies, EBM/11 did not react with granulocytes, lymphocytes, plasma cells, platelets, endothelial and epithelial cells in paraffin wax sections. It did not label skin Langerhans' cells, microglial cells, and interdigitating reticulum cells (as in frozen sections). This study opens a new area for the specific identification by EBM/11 of mononuclear phagocyte system cells in archival biopsy specimens. It also raises the possibility that some monoclonal antibodies, believed to be reactive only in frozen sections, may react in archival tissue after limited proteolysis with an appropriate enzyme. (+info)