Mice, TransgenicProtein ConformationModels, MolecularMolecular Sequence DataAmino Acid SequenceProtein IsoformsProtein BindingProtein Structure, TertiaryBinding SitesMutationProtein Structure, SecondaryEscherichia coliKineticsCrystallography, X-RayCircular DichroismMolecular ConformationThermodynamicsSpecies SpecificitySequence Analysis, DNASpectrometry, FluorescenceBase SequenceTemperatureHydrogen-Ion ConcentrationMagnetic Resonance SpectroscopyProtein FoldingRNA, Ribosomal, 16SMolecular Dynamics SimulationRecombinant ProteinsNucleic Acid ConformationMice, Inbred StrainsStructure-Activity RelationshipLigandsNuclear Magnetic Resonance, BiomolecularIsoenzymesBacterial ProteinsDNA, RibosomalSequence Homology, Amino AcidProtein DenaturationBacterial Typing TechniquesCloning, MolecularGenes, BacterialModels, ChemicalMutagenesis, Site-DirectedVirulencePolymerase Chain ReactionPlasmidsEscherichia coli ProteinsPhenotypeCell LineHydrogen BondingSequence AlignmentProtein Structure, QuaternaryDNA, BacterialAmino Acid SubstitutionDimerizationComputer SimulationCattlePeptidesAnti-Bacterial AgentsBase CompositionElectrophoresis, Polyacrylamide GelSubstrate SpecificityEpitopesAlternative SplicingCatalytic DomainMicrobial Sensitivity TestsTryptophanDNA PrimersCatalysisAllosteric RegulationAdenosine TriphosphateIsomerismPeptide FragmentsSolutionsHydrolysisDNARabbitsPolymorphism, Single-Stranded ConformationalCulture MediaSerotypingSpectrophotometry, UltravioletProteinsTime FactorsMolecular StructureRNA, BacterialModels, BiologicalRNA, MessengerFluorescence Resonance Energy TransferCell MembraneGenetic VariationGenotypeCysteineAntibodies, MonoclonalProtein MultimerizationMembrane ProteinsGenes, rRNACarrier ProteinsDrug Resistance, MicrobialHot TemperatureSolvents