Signal TransductionMolecular Sequence DataGene Expression RegulationMutationProtein BindingCells, CulturedModels, BiologicalRNA, MessengerCell LineTranscription FactorsApoptosisCell Line, TumorAmino Acid SequencePhosphorylationTranscription, GeneticPromoter Regions, GeneticBase SequenceGene Expression ProfilingProtein Structure, TertiaryReverse Transcriptase Polymerase Chain ReactionBlotting, WesternDNA-Binding ProteinsBinding SitesTransfectionCell DifferentiationCell ProliferationMice, Inbred C57BLModels, MolecularDown-RegulationUp-RegulationEnzyme ActivationMice, KnockoutGene Expression Regulation, DevelopmentalMembrane ProteinsProtein TransportGene ExpressionOligonucleotide Array Sequence AnalysisRNA, Small InterferingNF-kappa BCarrier ProteinsNuclear ProteinsPhenotypeRNA InterferenceGene Expression Regulation, NeoplasticMice, TransgenicCell MovementTime FactorsTranscriptional ActivationDisease Models, AnimalNeuronsHEK293 CellsNerve Tissue ProteinsRepressor ProteinsDNA PrimersProtein-Serine-Threonine KinasesCell SurvivalImmunoprecipitationTrans-ActivatorsTumor Cells, CulturedHomeodomain ProteinsDose-Response Relationship, DrugRecombinant ProteinsHeLa CellsEnzyme InhibitorsCell CycleProtein ConformationRats, Sprague-DawleyReactive Oxygen SpeciesCell NucleusKineticsRecombinant Fusion ProteinsProto-Oncogene Proteins c-aktImmunohistochemistryGene Knockdown TechniquesGene Expression Regulation, PlantProto-Oncogene ProteinsMitochondriaCell MembraneDNAGenes, ReporterSequence Homology, Amino AcidTranscriptomeIntracellular Signaling Peptides and ProteinsReal-Time Polymerase Chain ReactionCalciumProteinsMAP Kinase Signaling SystemDrosophila ProteinsEpithelial CellsExtracellular Signal-Regulated MAP KinasesNeoplasmsDNA, ComplementaryCell DivisionCOS CellsOxidative StressPhosphatidylinositol 3-KinasesResponse ElementsCloning, MolecularGene Expression Regulation, EnzymologicAdaptor Proteins, Signal Transducing