Islets of LangerhansInsulinIslets of Langerhans TransplantationReceptor, InsulinGlucoseInsulin-Secreting CellsHormonesGlucagonInsulin ResistanceGlucagon-Secreting CellsInsulinomaDiabetes Mellitus, Type 1PancreasFollicle Stimulating HormoneLuteinizing HormoneIslet Amyloid PolypeptideThyroid HormonesDiabetes Mellitus, ExperimentalProinsulinBlood GlucoseGlucose Tolerance TestHypoglycemic AgentsInsulin Receptor Substrate ProteinsCells, CulturedDiabetes Mellitus, Type 2SomatostatinAdenoma, Islet CellGonadotropin-Releasing HormoneInsulin AntibodiesParathyroid HormoneRats, WistarInsulin AntagonistsInsulin, Long-ActingSecretory RateC-PeptideRNA, MessengerSomatostatin-Secreting CellsStreptozocinGonadal Steroid HormonesHyperglycemiaPancreatic HormonesMice, Inbred C57BLSignal TransductionCalciumHuman Growth HormoneCell LineDiazoxideTime FactorsAdrenocorticotropic HormoneLiverRats, Inbred StrainsRats, Sprague-DawleyMice, Inbred NODGlucagon-Like Peptide 1Dose-Response Relationship, DrugGene Expression RegulationHyperinsulinismTolbutamideMannoheptuloseAlloxanGlucokinaseObesityReceptors, Thyroid HormoneMolecular Sequence DataAdipose TissueInsulin LisproGlucose Clamp TechniqueKineticsPancreatic PolypeptideGlucose Transporter Type 2Diabetes MellitusMice, ObeseMice, TransgenicImmunohistochemistryPituitary HormonesMice, KnockoutFastingBody WeightCarcinoma, Islet CellHomeostasisHypoglycemiaProlactinGene ExpressionPituitary GlandInsulin Infusion SystemsPeptide HormonesPhosphorylationCyclic AMPTriiodothyronineFatty Acids, NonesterifiedStimulation, ChemicalExocytosisEstradiolInsulin-Like Growth Factor IGlucose IntoleranceLeptinReverse Transcriptase Polymerase Chain ReactionAmino Acid SequenceInsulin AspartProglucagon