Unfolded Protein ResponseActivating Transcription Factor 6Endoplasmic ReticulumEndoplasmic Reticulum StressProtein FoldingTranscription Factor CHOPActivating Transcription Factor 4eIF-2 KinaseTunicamycinMolecular ChaperonesHeat-Shock ProteinsStress, PhysiologicalSignal TransductionEndoribonucleasesBasic-Leucine Zipper Transcription FactorsTranscription FactorsEukaryotic Initiation Factor-2ApoptosisProtein-Serine-Threonine KinasesDNA-Binding ProteinsProtein DenaturationCell LineCaspase 12Membrane ProteinsGene Expression RegulationCell Line, TumorRNA, MessengerCaspases, InitiatorCells, CulturedMutationProtein UnfoldingPhenylbutyratesPhosphorylationModels, BiologicalSaccharomyces cerevisiae ProteinsAutophagyRNA SplicingAcute-Phase ProteinsThapsigarginSaccharomyces cerevisiaeProtein TransportCell SurvivalBlotting, WesternMolecular Sequence DataProteasome InhibitorsCell DeathHSP70 Heat-Shock ProteinsDNA DamageOxidative StressHeLa CellsUp-RegulationFibroblastsTranscription, GeneticEndoplasmic Reticulum, RoughProteasome Endopeptidase ComplexFungal ProteinsHeat-Shock ResponseNuclear ProteinsRNA InterferenceRNA, Small InterferingMembrane GlycoproteinsGene Expression ProfilingMice, Inbred C57BLEndoplasmic Reticulum-Associated DegradationReverse Transcriptase Polymerase Chain ReactionHomeostasisProtein BiosynthesisProtein BindingSecretory PathwayTransfectionProtein Disulfide-IsomerasesMice, KnockoutEnzyme ActivationGene Expression Regulation, FungalRepressor ProteinsCCAAT-Enhancer-Binding ProteinsCaenorhabditis elegans ProteinsDithiothreitolAcute-Phase ReactionOligonucleotide Array Sequence AnalysisCaenorhabditis elegansPyrazinesBase SequenceAmino Acid SequenceBoronic AcidsCell Cycle ProteinsGene ExpressionTime FactorsHaptoglobinsGene Knockdown TechniquesNIH 3T3 CellsProteinsProteostasis DeficienciesUbiquitinCell CycleProtein Structure, TertiaryHEK293 CellsCell NucleusReactive Oxygen SpeciesCalreticulin