Energy MetabolismApoptosisEnergy IntakeLipid MetabolismGlucoseMitochondriaApoptosis Regulatory ProteinsCaspasesCaspase 3GlycolysisProto-Oncogene Proteins c-bcl-2Energy TransferInhibitor of Apoptosis ProteinsAdenosine TriphosphateSignal TransductionCells, CulturedCell Line, TumorOxygen ConsumptionCell SurvivalLactic AcidLiverTime FactorsDNA FragmentationOxidation-ReductionModels, BiologicalKineticsCell LineIn Situ Nick-End LabelingPhosphocreatineBiological Transportbcl-2-Associated X ProteinX-Linked Inhibitor of Apoptosis ProteinLactatesEnzyme ActivationOxidative PhosphorylationBasal MetabolismBlotting, WesternRNA, MessengerApoptosis Inducing FactorDose-Response Relationship, DrugTumor Cells, CulturedMice, Inbred C57BLCASP8 and FADD-Like Apoptosis Regulating ProteinGene Expression RegulationRats, Sprague-DawleyMetabolismMagnetic Resonance SpectroscopyCaspase 9Caspase InhibitorsMuscle, SkeletalCalorimetry, IndirectTumor Suppressor Protein p53Cell ProliferationMolecular Sequence DataCytochromes cInsulinCitric Acid CycleCaspase 8Mice, KnockoutMyocardiumBody WeightReactive Oxygen SpeciesBrainRats, WistarMutationOxidative StressCarrier ProteinsEnzyme InhibitorsFas Ligand ProteinDeoxyglucoseReverse Transcriptase Polymerase Chain ReactionHomeostasisPhosphorylationGene Expression ProfilingFatty AcidsMitochondrial Proteinsbcl-X ProteinAntineoplastic AgentsProteinsOxygenFlow CytometryTransfectionMembrane Potential, MitochondrialAnnexin A5Pyruvic AcidGene ExpressionHydrogen-Ion ConcentrationDown-RegulationEatingCell CycleCell DivisionMetabolic Networks and PathwaysNitrogenAdipose TissueUp-RegulationTranscription FactorsBlood GlucosePhosphatesRNA, Small InterferingCarbon