Circadian clock resetting in the mouse changes with age. (1/573)

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Chronopharmaceutical drug delivery systems: Hurdles, hype or hope? (2/573)

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Interplay between low-temperature pathways and light reduction. (3/573)

Low temperature is one of the major factors that adversely affect crop yields by causing restraints on plant growth and productivity. However, most temperate plants have the ability to acclimate to cooler temperatures. Cold acclimation is a process which increases the freezing tolerance of an organism after exposure to low, non-freezing temperatures. The main trigger is a decrease in temperature levels, but light reduction has also been shown to have an important impact on acquired tolerance. Since the lowest temperatures are commonly reached during the night hours in winter time and is an annually recurring event, a favorable trait for plants is the possibility of sensing an imminent cold period. Consequently, extensive crosstalk between light- and temperature signaling pathways has been demonstrated and in this review interesting interaction points that have been previously reported in the literature are highlighted.  (+info)

Heritable circadian period length in a wild bird population. (4/573)

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Circadian rhythms in gene expression: Relationship to physiology, disease, drug disposition and drug action. (5/573)

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PERsuading nuclear receptors to dance the circadian rhythm. (6/573)

The recurring light/dark cycle that has a period length of about 24 hours has been internalized in various organisms in the form of a circadian clock. This clock allows a precise orchestration of biochemical and physiological processes in the body thus improving performance. Recently, we found that the clock component PERIOD2 (PER2) can coordinate transcriptional regulation of metabolic, physiological, or behavioral pathways by interacting with nuclear receptors. PER2 appears to act as co-regulator of nuclear receptors linking clock function and transcriptional regulation at the level of protein-protein interactions. Here, we provide additional evidence for modulation of nuclear receptor dependent transcription by PER2 underscoring the broad implication of our finding. Taken together, our findings provide a base for the understanding of various disorders including mood disorders that have their roots in a temporal deregulation of basic metabolic processes.  (+info)

Circadian clocks in the ovary. (7/573)

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Similarities in the circadian clock and photoperiodism in plants. (8/573)

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