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  • Anatomia 169 domande A branch of biology dealing with the structure of organisms.
    • Regioni Del Corpo 15 domande Anatomical areas of the body.
    • Sistema Muscoloscheletrico 47 domande The MUSCLES, bones (BONE AND BONES), and CARTILAGE of the body.
    • Apparato Digerente 16 domande A group of organs stretching from the MOUTH to the ANUS, serving to breakdown foods, assimilate nutrients, and eliminate waste. In humans, the digestive system includes the GASTROINTESTINAL TRACT and the accessory glands (LIVER; BILIARY TRACT; PANCREAS).
    • Apparato Respiratorio 4 domande The tubular and cavernous organs and structures, by means of which pulmonary ventilation and gas exchange between ambient air and the blood are brought about.
    • Apparato Urogenitale 14 domande All the organs involved in reproduction and the formation and release of URINE. It includes the kidneys, ureters, BLADDER; URETHRA, and the organs of reproduction - ovaries, UTERUS; FALLOPIAN TUBES; VAGINA; and CLITORIS in women and the testes; SEMINAL VESICLES; PROSTATE; seminal ducts; and PENIS in men.
    • Sistema Endocrino 1 quesito The system of glands that release their secretions (hormones) directly into the circulatory system. In addition to the ENDOCRINE GLANDS, included are the CHROMAFFIN SYSTEM and the NEUROSECRETORY SYSTEMS.
    • Sistema Cardiovascolare 6 domande The HEART and the BLOOD VESSELS by which BLOOD is pumped and circulated through the body.
    • Sistema Nervoso 7 domande The entire nerve apparatus, composed of a central part, the brain and spinal cord, and a peripheral part, the cranial and spinal nerves, autonomic ganglia, and plexuses. (Stedman, 26th ed)
    • Organi Del Senso 3 domande
    • Tessuti 7 domande Collections of differentiated CELLS, such as EPITHELIUM; CONNECTIVE TISSUE; MUSCLES; and NERVE TISSUE. Tissues are cooperatively arranged to form organs with specialized functions such as RESPIRATION; DIGESTION; REPRODUCTION; MOVEMENT; and others.
    • Cellule 8 domande The fundamental, structural, and functional units or subunits of living organisms. They are composed of CYTOPLASM containing various ORGANELLES and a CELL MEMBRANE boundary.
    • Liquidi E Secrezioni 13 domande Liquid substances produced by living organisms to fulfill specific functions or excreted as waste.
    • Anatomia Animale 5 domande Organs and other anatomical structures of non-human vertebrate and invertebrate animals.
    • Sistema Stomatognatico 4 domande The mouth, teeth, jaws, pharynx, and related structures as they relate to mastication, deglutition, and speech.
    • Sistema Ematico E Immunitario 2 domande Organs involved in the production of BLOOD, including the cellular and the molecular components essential in providing defense against foreign organisms or substances.
      • Sangue 0 domande The body fluid that circulates in the vascular system (BLOOD VESSELS). Whole blood includes PLASMA and BLOOD CELLS.
      • Sistema Ematopoietico 0 domande
      • Sistema Immunitario 0 domande The body's defense mechanism against foreign organisms or substances and deviant native cells. It includes the humoral immune response and the cell-mediated response and consists of a complex of interrelated cellular, molecular, and genetic components.
        • Cellule Producenti Anticorpi 0 domande Cells of the lymphoid series that can react with antigen to produce specific cell products called antibodies. Various cell subpopulations, often B-lymphocytes, can be defined, based on the different classes of immunoglobulins that they synthesize.
        • Cellule Presentanti L'Antigene 0 domande A heterogeneous group of immunocompetent cells that mediate the cellular immune response by processing and presenting antigens to the T-cells. Traditional antigen-presenting cells include MACROPHAGES; DENDRITIC CELLS; LANGERHANS CELLS; and B-LYMPHOCYTES. FOLLICULAR DENDRITIC CELLS are not traditional antigen-presenting cells, but because they hold antigen on their cell surface in the form of IMMUNE COMPLEXES for B-cell recognition they are considered so by some authors.
        • Midollo Osseo 0 domande The soft tissue filling the cavities of bones. Bone marrow exists in two types, yellow and red. Yellow marrow is found in the large cavities of large bones and consists mostly of fat cells and a few primitive blood cells. Red marrow is a hematopoietic tissue and is the site of production of erythrocytes and granular leukocytes. Bone marrow is made up of a framework of connective tissue containing branching fibers with the frame being filled with marrow cells.
        • Cellule Enterocromaffini 0 domande A subtype of enteroendocrine cells found in the gastrointestinal MUCOSA, particularly in the glands of PYLORIC ANTRUM; DUODENUM; and ILEUM. These cells secrete mainly SEROTONIN and some neuropeptides. Their secretory granules stain readily with silver (argentaffin stain).
        • Immunological Synapses 0 domande The interfaces between T-CELLS and ANTIGEN-PRESENTING CELLS. Supramolecular organization of proteins takes place at these synapses involving various types of immune cells. Immunological synapses can have several functions including LYMPHOCYTE ACTIVATION; enhancing, balancing, or terminating signaling; or directing cytokine secretion.
        • Leucociti 0 domande White blood cells. These include granular leukocytes (BASOPHILS; EOSINOPHILS; and NEUTROPHILS) as well as non-granular leukocytes (LYMPHOCYTES and MONOCYTES).
          • Granulociti 0 domande Leukocytes with abundant granules in the cytoplasm. They are divided into three groups according to the staining properties of the granules: neutrophilic, eosinophilic, and basophilic. Mature granulocytes are the NEUTROPHILS; EOSINOPHILS; and BASOPHILS.
          • Leucociti Mononucleari 0 domande Mature LYMPHOCYTES and MONOCYTES transported by the blood to the body's extravascular space. They are morphologically distinguishable from mature granulocytic leukocytes by their large, non-lobed nuclei and lack of coarse, heavily stained cytoplasmic granules.
            • Cytokine-Induced Killer Cells 0 domande Mononuclear leukocytes that have been expanded in CELL CULTURE and activated with CYTOKINES such as INTERLEUKIN-2 to produce large numbers of highly cytotoxic cells.
            • Linfociti 0 domande White blood cells formed in the body's lymphoid tissue. The nucleus is round or ovoid with coarse, irregularly clumped chromatin while the cytoplasm is typically pale blue with azurophilic (if any) granules. Most lymphocytes can be classified as either T or B (with subpopulations of each), or NATURAL KILLER CELLS.
              • Cellule Natural Killer 0 domande Bone marrow-derived lymphocytes that possess cytotoxic properties, classically directed against transformed and virus-infected cells. Unlike T CELLS; and B CELLS; NK CELLS are not antigen specific. The cytotoxicity of natural killer cells is determined by the collective signaling of an array of inhibitory and stimulatory CELL SURFACE RECEPTORS. A subset of T-LYMPHOCYTES referred to as NATURAL KILLER T CELLS shares some of the properties of this cell type.
              • Sottopopolazioni Linfocitarie 0 domande A classification of lymphocytes based on structurally or functionally different populations of cells.
              • Linfociti B 0 domande Lymphoid cells concerned with humoral immunity. They are short-lived cells resembling bursa-derived lymphocytes of birds in their production of immunoglobulin upon appropriate stimulation.
              • Linfociti T 0 domande Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.
                • Linfociti T Cd4 Positivi 0 domande A critical subpopulation of T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the T4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes.
                • Linfociti T Cd8 Positivi 0 domande A critical subpopulation of regulatory T-lymphocytes involved in MHC Class I-restricted interactions. They include both cytotoxic T-lymphocytes (T-LYMPHOCYTES, CYTOTOXIC) and CD8+ suppressor T-lymphocytes.
                • Cellule Jurkat 0 domande A CELL LINE derived from human T-CELL LEUKEMIA and used to determine the mechanism of differential susceptibility to anti-cancer drugs and radiation.
                • Natural Killer T-Cells 0 domande A specialized subset of T-LYMPHOCYTES that exhibit features of INNATE IMMUNITY similar to that of NATURAL KILLER CELLS. They are reactive to glycolipids presented in the context of the major histocompatibility complex (MHC) class I-like molecule, CD1D ANTIGEN.
                • Sottopopolazioni Di Linfociti T 0 domande A classification of T-lymphocytes, especially into helper/inducer, suppressor/effector, and cytotoxic subsets, based on structurally or functionally different populations of cells.
                  • Linfociti T Citotossici 0 domande Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC), in vivo during a graft-versus-host (GVH) reaction, or after immunization with an allograft, tumor cell or virally transformed or chemically modified target cell. The lytic phenomenon is sometimes referred to as cell-mediated lympholysis (CML). These CD8-positive cells are distinct from NATURAL KILLER CELLS and NATURAL KILLER T-CELLS. There are two effector phenotypes: TC1 and TC2.
                  • Linfociti T Helper-Inducer 0 domande Subpopulation of CD4+ lymphocytes that cooperate with other lymphocytes (either T or B) to initiate a variety of immune functions. For example, helper-inducer T-cells cooperate with B-cells to produce antibodies to thymus-dependent antigens and with other subpopulations of T-cells to initiate a variety of cell-mediated immune functions.
                  • Linfociti T Regolatori 0 domande CD4-positive T cells that inhibit immunopathology or autoimmune disease in vivo. They inhibit the immune response by influencing the activity of other cell types. Regulatory T-cells include naturally occurring CD4+CD25+ cells, IL-10 secreting Tr1 cells, and Th3 cells.
              • Linfociti Null 0 domande A class of lymphocytes characterized by the lack of surface markers specific for either T or B lymphocytes.
              • Linfociti Tumor-Infiltrating 0 domande Lymphocytes that show specificity for autologous tumor cells. Ex vivo isolation and culturing of TIL with interleukin-2, followed by reinfusion into the patient, is one form of adoptive immunotherapy of cancer.
            • Monociti 0 domande Large, phagocytic mononuclear leukocytes produced in the vertebrate BONE MARROW and released into the BLOOD; contain a large, oval or somewhat indented nucleus surrounded by voluminous cytoplasm and numerous organelles.
        • Sistema Linfatico 0 domande A system of organs and tissues that process and transport immune cells and LYMPH.
        • Mastociti 0 domande Granulated cells that are found in almost all tissues, most abundantly in the skin and the gastrointestinal tract. Like the BASOPHILS, mast cells contain large amounts of HISTAMINE and HEPARIN. Unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood. Mast cells, derived from the bone marrow stem cells, are regulated by the STEM CELL FACTOR.
        • Fagociti 0 domande Cells that can carry out the process of PHAGOCYTOSIS.
        • Mononuclear Phagocyte System 0 domande Mononuclear cells with pronounced phagocytic ability that are distributed extensively in lymphoid and other organs. It includes MACROPHAGES and their precursors; PHAGOCYTES; KUPFFER CELLS; HISTIOCYTES; DENDRITIC CELLS; LANGERHANS CELLS; and MICROGLIA. The term mononuclear phagocyte system has replaced the former reticuloendothelial system, which also included less active phagocytic cells such as fibroblasts and endothelial cells. (From Illustrated Dictionary of Immunology, 2d ed.)
    • Strutture Embrionali 1 quesito The anatomical parts that make up an organism in the early stages of development.
    • Apparato Tegumentario 1 quesito The outer covering of the body composed of the SKIN and the skin appendages, which are the HAIR, the NAILS; and the SEBACEOUS GLANDS and the SWEAT GLANDS and their ducts.
    • Plant Structures 0 domande The parts of plants, including SEEDS.
    • Fungal Structures 0 domande The parts of fungi.
    • Bacterial Structures 1 quesito The parts of bacteria.
    • Viral Structures 0 domande The structural parts of the VIRION.
  • Organismi 49 domande Any living biological entity, such as an animal, plant, fungus, or bacterium.
  • Malattie 323 domande Any impairment of normal physiological function affecting all or part of an organism, esp a specific pathological change caused by infection, stress, etc, producing characteristic symptoms; illness or sickness in general.
  • Sostanze chimiche e Farmaci 202 domande Any substance used in or resulting from a reaction involving changes to atoms or molecules, especially one derived artificially for practical use and any synthetic, semisynthetic, or natural chemical substance used in the treatment, prevention, or diagnosis of disease, or for other medical reasons.
  • Tecniche ed apparecchiature analitiche, diagnostiche e terapeutiche 109 domande
  • Psichiatria e Psicologia 14 domande The branches of medicine concerned with the diagnosis and treatment of mental illness and the scientific study of all forms of human and animal behaviour, sometimes concerned with the methods through which behaviour can be modified.
  • Scienze biologiche 31 domande
  • Scienze naturali 17 domande
  • Antropologia, Formazione, Sociologia e fenomeni sociali 3 domande
  • Tecnologia, Industria, Agricoltura 4 domande
  • Discipline umanistiche 1 quesito The study of literature, philosophy, and the arts.
  • Scienza dell'informazione 0 domande The field of knowledge, theory, and technology dealing with the collection of facts and figures, and the processes and methods involved in their manipulation, storage, dissemination, publication, and retrieval. It includes the fields of COMMUNICATION; PUBLISHING; LIBRARY SCIENCE; and informatics.
  • Gruppi di persone 8 domande
  • Assistenza sanitaria 34 domande
  • Caratteristiche della Pubblicazione 4 domande
  • Luoghi geografici 7 domande The study of the natural features of the earth's surface, including topography, climate, soil, vegetation, etc, and man's response to them.
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