What will happen if I use meth while taking solumedrol. I know it sounds bad, but my MS is really weakening me and the meth actually helps me to continue working. I have always been a person that needs to stay busy. All the time and if it wasn't for the meth I would feel like I may as well already be bedridden. My mom had MS so I know what the future holds for me. I'm just trying to feel somewhat like a normal person.