0 votes
13 views
in Pharmaceutical Preparations by

Lipoparticles are specialized VLPs that incorporate high concentrations of target membrane proteins in their native conformation. A lipoparticle usually consists of a retroviral core protein (Gag) and a conformational-complex membrane protein, co-expressed, assembled and released from host cells. Gag core proteins self-assemble at the plasma membrane, where they bud off and capture target membrane proteins (Figure 1). Since the membrane proteins within lipoparticles are derived directly from the cell surface without mechanical disruption or detergents, the native structure and orientation of the membrane proteins are retained.

Your answer

Your name to display (optional):
Privacy: Your email address will only be used for sending these notifications.
Anti-spam verification:
To avoid this verification in future, please log in or register.
Welcome to lookformedical.com, where you can ask questions and receive answers from other members of the community.

4.3k questions

2.2k answers

164 comments

6.9k users

Disclaimer: We do not evaluate or guarantee the accuracy of any content in this site.
...