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Variation such as mutation, selection, replication, sex&recombination and gene flow along with heredity repeats for millions of generations-every biologist is familiar with how evolution has made the incredible diversity and adaptations found in the natural world. Directed evolution uses a similar strategy to create biomolecules for being used in diverse fields spanning industrial production, medical science, and basic research. 

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Evolution is a gradual transmission of traits over time from generation to generation. Larger the gap between generations, higher the evolutionDirected evolution, is an induced and artificial  laboratory process to modify the biological entities with desired traits. I t is a powerful tool in basic and applied biology.It is a technique  used in protein engineering that mimics the process of natural selection 

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