RIP kinases (receptor-interacting protein kinases) are a class of serine/threonine protein kinases. In humans, five different ... "Receptor-interacting protein (RIP) kinase family". Cellular & Molecular Immunology. 7 (4): 243-249. doi:10.1038/cmi.2010.10. ... Portal: Biology \ v t e (EC 2.7.11, Human proteins, Protein kinases, All stub articles, EC 2.7 stubs). ... RIP kinases are known: RIPK1 RIPK2 RIPK3 RIPK4 RIPK5 Zhang, Duanwu; Lin, Juan; Han, Jiahuai (July 2010). " ...

This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded ... Receptor-interacting serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the RIPK2 gene. ... "Entrez Gene: RIPK2 receptor-interacting serine-threonine kinase 2". McCarthy, J V; Ni J; Dixit V M (Jul 1998). "RIP2 is a novel ... 2002). "Involvement of receptor-interacting protein 2 in innate and adaptive immune responses". Nature. 416 (6877): 190-4. ...

The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. It ... "RIPK3 - Receptor-interacting serine/threonine-protein kinase 3 - Homo sapiens (Human) - RIPK3 gene & protein". www.uniprot.org ... Receptor-interacting serine/threonine-protein kinase 3 is an enzyme that is encoded by the RIPK3 gene in humans. ... "Entrez Gene: RIPK3 receptor-interacting serine-threonine kinase 3". Li J, McQuade T, Siemer AB, Napetschnig J, Moriwaki K, ...

This protein is also known as the Dusty protein kinase and the Receptor interacting protein 5 (RIP5). This gene encodes a dual ... Dual serine/threonine and tyrosine protein kinase is an enzyme that in humans is encoded by the DSTYK gene. ... "Entrez Gene: RIPK5 receptor interacting protein kinase 5". Hoek KS, Schlegel NC, Eichhoff OM, et al. (2008). "Novel MITF ... serine/threonine and tyrosine protein kinase which is expressed in multiple tissues. Multiple alternatively spliced transcript ...

Receptor-interacting serine/threonine-protein kinase 4 is an enzyme that in humans is encoded by the RIPK4 gene. The protein ... encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can ... "Entrez Gene: RIPK4 receptor-interacting serine-threonine kinase 4". Chen, L; Haider K; Ponda M; Cariappa A; Rowitch D; Pillai S ... 2000). "DIK, a novel protein kinase that interacts with protein kinase Cdelta. Cloning, characterization, and gene analysis". J ...

This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, ... Chen D, Li X, Zhai Z, Shu HB (2002). "A novel zinc finger protein interacts with receptor-interacting protein (RIP) and ... "A novel zinc finger protein interacts with receptor-interacting protein (RIP) and inhibits tumor necrosis factor (TNF)- and IL1 ... receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and ...

These activation inducers converge on receptor-interacting serine/threonine-protein kinase 3 (RIPK3) and mixed lineage kinase ... It binds to several pattern recognition receptors (PRRs) such as Toll-like receptors (TLR) 2 and 4, which are expressed on APCs ... Detection of such PAMPs by some members of Nod-like receptor family (NLRs), absent in melanoma 2 (AIM2) or pyrin leads to the ... These proteins contain oligomerization NACHT domains, CARD domains and some also contain similar pyrin (PYR) domains. Caspase 1 ...

Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) functions in a variety of cellular pathways related to both cell ... Receptor-interacting serine/threonine-protein kinase 1) at the PDBe-KB. (Articles with short description, Short description is ... "Entrez Gene: RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1". Festjens N, Vanden Berghe T, Cornelis S, ... Online Mendelian Inheritance in Man (OMIM): Receptor-interacting serine/threonine kinase 1 (RIPK1) - 603453 Zhu G, Wu CJ, Zhao ...

The protein encoded by this gene is a member of the serine/threonine protein kinase family and is a catalytic subunit of PKA. ... PRKACB has been shown to interact with Ryanodine receptor 2 and Low affinity nerve growth factor receptor. GRCh38: Ensembl ... "The cAMP-dependent protein kinase A and protein kinase C-beta pathways synergistically interact to activate HIV-1 transcription ... 2003). "Mutants of protein kinase A that mimic the ATP-binding site of protein kinase B (AKT)". J. Mol. Biol. 329 (5): 1021-34 ...

These proteins interact with a conserved family of cell surface serine/threonine-specific protein kinase receptors, and ... They interact with TGF-beta receptors. Many proteins have since been described as members of the TGF-β superfamily in a variety ... Articles with short description, Short description matches Wikidata, Developmental genes and proteins, TGFβ domain, Protein ... Proteins from the TGF-beta superfamily are only active as homo- or heterodimer; the two chains being linked by a single ...

"NM23-H1 tumor suppressor physically interacts with serine-threonine kinase receptor-associated protein, a transforming growth ... Serine-threonine kinase receptor-associated protein is an enzyme that in humans is encoded by the STRAP gene. STRAP has been ... "Entrez Gene: STRAP serine/threonine kinase receptor associated protein". Datta PK, Moses HL (May 2000). "STRAP and Smad7 ... signaling and PDK1 kinase activity by physical interaction between PDK1 and serine-threonine kinase receptor-associated protein ...

The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic ... Barbara NP, Wrana JL, Letarte M (January 1999). "Endoglin is an accessory protein that interacts with the signaling receptor ... activin A receptor type II-like kinase, 53kDa) is a membrane-bound TGF beta receptor protein of the TGF-beta receptor family ... Kawabata M, Chytil A, Moses HL (March 1995). "Cloning of a novel type II serine/threonine kinase receptor through interaction ...

... hormones stored as amyloids within endocrine secretory granules Receptor-interacting serine/threonine-protein kinase 1/3 (RIP1/ ... protein receptors, soluble proteins, RNAs, small metabolites, etc. In the clinical setting, amyloid diseases are typically ... Ferrone F (1999). "Analysis of protein aggregation kinetics". Amyloid, Prions, and Other Protein Aggregates. Methods in ... Functional amyloid in Homo sapiens: Intralumenal domain of melanocyte protein PMEL Peptide/protein ...

... receptor-interacting serine/threonine kinase 2 (RIPK2) and calcium/calmodulin-dependent protein kinase 1α (CAMK1α). Lidgren, ... The effects barettin has on inflammation may be due to its inhibitory properties on two protein kinases, ... "The immunomodulatory effects of barettin and involvement of the kinases CAMK1α and RIPK2". Immunopharmacology and ...

Serine/threonine-protein kinase PAK 6 is an enzyme that in humans is encoded by the PAK6 gene. PAK6 belongs to the Group II PAK ... The PAK6 was originally cloned as an androgen receptor interacting kinase which can be stimulated by androgen receptor but not ... apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor ( ... PAK6 interacts with junctional protein IQGAP1, E3 ligase Mdm2, and leucine-rich repeat kinase 2 (LRRK2). PAK6 has been shown to ...

Serine/threonine-protein kinase D1 is an enzyme that in humans is encoded by the PRKD1 gene. Members of the protein kinase D ( ... "The pleckstrin homology domain of protein kinase D interacts preferentially with the eta isoform of protein kinase C". J. Biol ... "Protein kinase C mu (PKC mu) associates with the B cell antigen receptor complex and regulates lymphocyte signaling". Immunity ... Protein kinase D1 has been shown to interact with: Bruton's tyrosine kinase, C1QBP, Centaurin, alpha 1, Metallothionein 2A, and ...

Protein Kinase C (pKC) phosphorylates TEAD1 on serine and threonine next to the last alpha loop in the TEA domain. This ... TEAD1 interacts with all members of the SRC family of steroid receptor coactivators. In HeLa cells TEAD1 and SRC induce gene ... Protein Kinase A (pKA) can phosphorylate TEAD1 at serine 102, after the TEA domain. This phosphorylation is needed for the ... TEAD proteins and MEF2 (myocyte enhancer factor 2) interact physically. The binding of MEF2 on DNA induces and potentiates ...

Serine/threonine-protein kinase receptor R3 is an enzyme that in humans is encoded by the ACVRL1 gene. ACVRL1 is a receptor in ... interacts with the transforming growth factor-beta family of receptor serine-threonine kinases". The Journal of Biological ... other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. ... "Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity". ...

Serine/threonine-protein kinase LMTK2 also known as Lemur tyrosine kinase 2 (LMTK2) is an enzyme that in humans is encoded by ... This protein interacts with several other proteins, such as androgen receptor, inhibitor-2 (Inh2), protein phosphatase-1 (PP1C ... It phosphorylates other proteins, and is itself also phosphorylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 ... Kawa S, Fujimoto J, Tezuka T, Nakazawa T, Yamamoto T (Mar 2004). "Involvement of BREK, a serine/threonine kinase enriched in ...

CTR1 is a serine/threonine protein kinase that functions as a negative regulator of ethylene signalling. It is a member of the ... Two proteins are crucial for interacting ethylene with the receptors, namely constitutive triple response 1 (CTR1) and ethylene ... ETR1 has histidine kinase activity, whereas ETR2, ERS2, and EIN4 have serine/threonine kinase activity, and ERS1 has both. The ... signaling protein mitogen-activated protein kinase (MAPK) kinase kinase. EIN2 is required for ethylene signalling and is part ...

... is a serine-threonine kinase that is closely related to other kinases that interact with members of the ... Among the substrates for DMPK proposed by in vitro studies are phospholemman, the dihydropyridine receptor, and the myosin ... Dystrophia myotonica protein kinase (DMPK) is a serine/threonine kinase composed of a kinase domain and a coiled-coil domain ... Myotonin-protein kinase (MT-PK) also known as myotonic dystrophy protein kinase (MDPK) or dystrophia myotonica protein kinase ( ...

MAP kinase-interacting serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the MKNK2 gene. MNK2 has ... Haribabu B, Snyderman R (October 1993). "Identification of additional members of human G-protein-coupled receptor kinase ... "Entrez Gene: MKNK2 MAP kinase interacting serine/threonine kinase 2". Scheper GC, Parra JL, Wilson M, Van Kollenburg B, ... "Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2". The EMBO Journal. 16 (8): 1909-1920. ...

C-terminus of PEPR 1 kinase domain showed a strong interaction with BIK 1 and phosphorylates BIK 1 on serine 236 and threonine ... PEPR 1 receptors are receptor kinases with extracellular LRR motifs. AtPEP1 interacts with the inner side of the PEPR 1 LRR ... Plant membrane PRR mainly consist of receptor like kinases and receptor like proteins. They sense PAMPs such as chitin from ... Leucine-rich repeat receptor like protein kinase (PEPR1 and PEPR2 in Arabidopsis thaliana and Xa21 in rice) are plant cell ...

... a serine-threonine kinase, and the adhesion and degranulation-promoting adaptor protein (ADAP) also known as FYB. Both these ... a novel Grb-2-related adapter protein that interacts with the activated T cell costimulatory receptor CD28". Journal of ... August 1996). "Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function". The ... "SLP-76 is a substrate of the high affinity IgE receptor-stimulated protein tyrosine kinases in rat basophilic leukemia cells". ...

... with a truncated portion of the BCR protein. Although the BCR region also expresses serine/threonine kinases, the tyrosine ... The fused BCR-ABL1 protein interacts with the interleukin-3 receptor beta(c) subunit and is moderated by an activation loop ... "The Tyrosine Kinase c-Abl Responds to DNA Damage by Activating the Homeodomain-interacting Protein Kinase 2". Journal of ... October 2004). "Chlorogenic acid inhibits Bcr-Abl tyrosine kinase and triggers p38 mitogen-activated protein kinase-dependent ...

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and ... "Protein kinase C gamma associates directly with the GluR4 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor ... PRKCG has been shown to interact with GRIA4. Protein kinase C GRCh38: Ensembl release 89: ENSG00000126583 - Ensembl, May 2017 ... The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and ...

TBK1 (TANK-binding kinase 1) is an enzyme with kinase activity. Specifically, it is a serine / threonine protein kinase. It is ... TANK-binding kinase 1 has been shown to interact with: NCK1, TANK, TRAF2 and TBKBP1 aka SINTBAD Transcription factors activated ... associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, ... The Nck adaptor protein binds to a serine/threonine kinase via an SH3 domain". The Journal of Biological Chemistry. 270 (13): ...

... , also known as RAC-beta serine/threonine-protein kinase, is an enzyme that in humans is encoded by the AKT2 gene. It ... encoding an adaptor molecule that interacts with the oncoprotein-serine/threonine kinase AKT2". Oncogene. 18 (35): 4891-8. doi: ... "Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance". J ... This gene is a putative oncogene encoding a protein belonging to the AKT subfamily of serine/threonine kinases that contain SH2 ...

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and ... PRKCB1 has been shown to interact with RIPK4, beta adrenergic receptor kinase, PDLIM5 and GNB2L1. Protein kinase C GRCh38: ... "Protein kinase C-associated kinase (PKK), a novel membrane-associated, ankyrin repeat-containing protein kinase". The Journal ... December 1996). "Protein-protein interaction of zinc finger LIM domains with protein kinase C". The Journal of Biological ...

This gene encodes a member of the serine/threonine protein kinase family and the TGFB receptor subfamily. The encoded protein ... TGF beta receptor 2 has been shown to interact with: AP2B1, Cyclin B2, Endoglin, Heat shock protein 90kDa alpha (cytosolic), ... Kawabata M, Chytil A, Moses HL (Mar 1995). "Cloning of a novel type II serine/threonine kinase receptor through interaction ... is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and ...