Minocycline
... reacts acidic in aqueous solution. Minocycline was patented in 1961 and came into commercial use in 1971. A topical ... Minocycline also has been used as a "last-ditch" treatment for toxoplasmosis in AIDS patients. Minocycline is somewhat ... Minocycline significantly reduces concentrations of the anti-HIV drug atazanavir in the body. Minocycline is quickly and nearly ... As mentioned above, minocycline harms ALS patients. Minocycline is also known to indirectly inhibit inducible nitric oxide ...
NMDA receptor antagonist
Minocycline. Neramexane: a memantine analogue with nootropic, antidepressant properties. Also a nicotinic acetylcholine ... Shultz RB, Zhong Y (May 2017). "Minocycline targets multiple secondary injury mechanisms in traumatic spinal cord injury". ...
Tooth whitening
Tetracycline and minocycline. Tetracycline is a broad-spectrum antibiotic, and its derivative minocycline is common in the ... Good, ML; Hussey, DL (August 2003). "Minocycline: stain devil?". The British Journal of Dermatology. 149 (2): 237-9. doi: ...
Drug rash with eosinophilia and systemic symptoms
"Tetracycline (doxycycline, minocycline)". Markel, A (October 2005). "Allopurinol-induced DRESS syndrome" (PDF). Israel Medical ... This is evident in the most commonly cited medications that cause the DRESS viz., allopurinol, sulfasalazine, and minocycline, ... minocycline and abacavir are the main culprit drugs causing severe lung involvement. However, lung involvement in this disorder ... it occurs more often in individuals taking minocycline, ampicillin, or sulfonamides, and is either a cardiac hypersensitivity ...
Tooth discoloration
Tetracycline is a broad spectrum antibiotic, and its derivative minocycline is common in the treatment of acne. The drug is ... Good, ML; Hussey, DL (August 2003). "Minocycline: stain devil?". The British Journal of Dermatology. 149 (2): 237-9. doi: ...
Multiple sclerosis drug pipeline
... more than 6.5 million people have been treated with minocycline for an average of 9 months, mostly for acne." Minocycline is ... Glatiramer acetate and minocycline. Good results Avonex and atorvastatin: Avonex (beta-1a) has also been combined with ... The only patient with gadolinium-enhancing lesions on MRI at 12 and 24 months was on half-dose minocycline. Clinical and MRI ... LDN is available to MS patients in the US by off-label prescription.[medical citation needed] minocycline: the antibiotic ...
Tigecycline
Minocycline has been shown to have anti-inflammatory and anti-apoptotic activities, inhibition of proteolysis and suppression ... Garrido-Mesa N, Zarzuelo A, Gálvez J (January 2013). "What is behind the non-antibiotic properties of minocycline?". ... Macdonald H, Kelly RG, Allen ES, Noble JF, Kanegis LA (September 1973). "Pharmacokinetic studies on minocycline in man". ... Goldstein FW, Kitzis MD, Acar JF (September 1994). "N,N-dimethylglycyl-amido derivative of minocycline and 6-demethyl-6- ...
Doxycycline
Singh S, Khanna D, Kalra S (2021). "Minocycline and Doxycycline: More Than Antibiotics". Curr Mol Pharmacol. 14 (6): 1046-1065 ... Research areas have included: Macular degeneration Rheumatoid arthritis instead of minocycline (both of which have demonstrated ... By comparison, the tetracycline antibiotic minocycline penetrates significantly better into the CSF and meninges. Doxycycline ... December 2012). "Rapid effectiveness of minocycline or doxycycline against macrolide-resistant Mycoplasma pneumoniae infection ...
Randi J. Hagerman
Megan Brooks (7 September 2010). "Minocycline Promising in Fragile X Syndrome". medscape.com. Retrieved 1 July 2016. Hagerman, ...
List of investigational antidepressants
Minocycline - microglia inhibitor and other actions; a 2018 systematic review and meta-analysis reported that the overall ... Rosenblat JD, McIntyre RS (February 2018). "Efficacy and tolerability of minocycline for depression: A systematic review and ... antidepressant effect size of minocycline compared to placebo was -0.78 (95% CI: -0.4 to -1.33, P=0.005), indicative of a large ...
Hidradenitis suppurativa
Popular antibiotics also include tetracycline and minocycline. Topical clindamycin has been shown to have an effect in double- ...
Amyotrophic lateral sclerosis research
... and minocycline); and drugs to improve mitochondria function (creatine, acetyl-L-carnitine, dexpramipexole, and olesoxime). ... minocycline, and NP001); antioxidants (acetylcysteine, glutathione, selegiline, vitamin E, and coenzyme Q); anti-apoptotic ...
Acne
Minocycline is an effective acne treatment, but it is not a first-line antibiotic due to a lack of evidence that it is better ... Garner SE, Eady A, Bennett C, Newton JN, Thomas K, Popescu CM (August 2012). "Minocycline for acne vulgaris: efficacy and ... The introduction of oral tetracycline antibiotics (such as minocycline) modified acne treatment in the 1950s. These reinforced ... doxycycline or minocycline). Doxycycline 40 milligrams daily (low-dose) appears to have similar efficacy to 100 milligrams ...
Ehrlichiosis
Doxycycline and minocycline are the medications of choice. For people allergic to antibiotics of the tetracycline class, ...
Chronic periodontitis
"Among the locally administered adjunctive antimicrobials, the most positive results occurred for tetracycline, minocycline, ... Minocycline is typically delivered via slim syringe applicators. Chlorhexidine impregnated chips are also available. Hydrogen ...
Marion Leboyer
Leboyer had considered setting up an AntibiAutism project "Minocycline treatment of High Functioning Autism Spectrum Disorder ... Smith, Kelly; Leyden, James J. (2005-09-01). "Safety of doxycycline and minocycline: A systematic review". Clinical ... Minocycline) in adults diagnosed with autism spectrum disorder without intellectual delay, was abandoned on the initiative of ...
Janice E. Clements
Her recent work includes the use of minocycline, a common antibiotic often used against acne, to protect against viral ... "Minocycline attenuates HIV infection and reactivation by suppressing cellular activation in human CD4+ T cells". The Journal of ... "Neuroprotective and anti-human immunodeficiency virus activity of minocycline". JAMA. 293 (16): 2003-11. doi:10.1001/jama. ...
M. Christine Zink
"Neuroprotective and anti-human immunodeficiency virus activity of minocycline". JAMA. 293 (16): 2003-11. doi:10.1001/jama. ...
Blue nails
Minocycline can also turn the nail plate blue-gray. Nail anatomy Nail diseases Wilson's disease James, William; Berger, Timothy ...
Rosacea
Oral antibiotics of the tetracycline class such as doxycycline, minocycline, and oxytetracycline are also commonly used and ... Treatment is typically with metronidazole, doxycycline, minocycline, or tetracycline. When the eyes are affected, azithromycin ...
Raphael M. Bonelli
Bonelli RM, Heuberger C, Reisecker F. Minocycline for Huntington's disease: an open label study. Neurology 2003; 60(5):883-4. ... Neuroprotection in Huntington's disease: A Two Year Study on Minocycline. International Clinical Psychopharmacology 2004; 19(6 ... Minocycline, Mirtazapine, Zotepine, Ziprasidone, Venlafaxine and antipsychotic drug holidays in Huntington's disease. In a ...
William Cook (entrepreneur)
Notable products included the Spectrum antibiotic-impregnated catheter (Rifamphin/Minocycline); the Gianturco-Roubin coronary ...
Nocardia
Minocycline is usually substituted when a sulfa cannot be given; high-dose imipenem and amikacin have also been used in severe ...
Neonatal jaundice
Preclinical studies have looked at minocycline to help prevent neurotoxicity. Clofibrate may decrease the duration of ...
Tetracycline antibiotics
Like minocycline, tigecycline binds to the bacterial 30S ribosome, blocking the entry of transfer RNA. This ultimately prevents ... Partial exceptions to these rules occur for doxycycline and minocycline, which may be taken with food (though not iron, ... However, the addition of an N,N,-dimethylglycylamido group at the 9 position of the minocycline molecule increases the affinity ... Although it is structurally related to minocycline, alterations to the molecule resulted in its expanded spectrum of activity ...
Habituation
Electrocortical changes associated with minocycline treatment in fragile X syndrome. J. Psychopharmacol. 27, 956-63. doi: ...
NMDA receptor
Shultz RB, Zhong Y (May 2017). "Minocycline targets multiple secondary injury mechanisms in traumatic spinal cord injury". ... an opioid analgesic Minocycline - an antibiotic Tramadol - an atypical opioid analgesic and serotonin releasing agent The NMDA ...
Sophoraflavanone G
When this compound is combined with vancomycin, minocycline, and rifampicin, the rates of inhibition increased, indicating a ... 2009), and ampicillin, gentamicin, minocycline, and vancomycin hydrochloride (Duka et al. 2010), sophoraflavanone G increases ...
Neuroprotection
Tikka TM, Koistinaho JE (June 2001). "Minocycline provides neuroprotection against N-methyl-D-aspartate neurotoxicity by ... Minocycline is a semi-synthetic tetracycline compound that is capable of crossing the blood brain barrier. It is known to be a ... inflammation and apoptosis by minocycline prevents retrovirus-induced neurodegeneration in mice". Brain Research. 1286: 174-184 ... for being neuroprotective and many studies are being done looking at the effects in neurodegenerative diseases Minocycline: ...
Leukopenia
Minocycline, a commonly prescribed antibiotic, is another drug known to cause leukopenia. There are also reports of leukopenia ...