Mannose
... mannose to prevent or treat UTIs. Mannose differs from glucose by inversion of the C-2 chiral center. Mannose displays a 4 C 1 ... α-Mannosidase Mannose receptor Mannan oligosaccharide-based nutritional supplements Rhamnose, 6-deoxy-L-mannose PTS Mannose- ... Mannose is a sugar monomer of the aldohexose series of carbohydrates. It is a C-2 epimer of glucose. Mannose is important in ... Mannose provides 2-5 kcal/g. It is partially excreted in the urine. The root of both "mannose" and "mannitol" is manna, which ...
Mannose receptor
Despite the similarities in mannose-binding between the mannose receptor and MBL, these differences suggest that mannose- ... As opposed to macrophages that use the mannose receptors for phagocytosis of particulate matter >200 nm, the mannose receptor ... binding by the mannose receptor evolved separately to that of other C-type lectins. Individually, the CRDs bind mannose with ... The mannose receptor is the only member of the family in which this domain is functional. The fibronectin type II repeat domain ...
Mannose isomerase
In enzymology, a mannose isomerase (EC 5.3.1.7) is an enzyme that catalyzes the chemical reaction D-mannose ⇌ {\displaystyle \ ... The systematic name of this enzyme class is D-mannose aldose-ketose-isomerase. Other names in common use include D-mannose ... This enzyme participates in fructose and mannose metabolism. Palleroni NJ, Doudoroff M (January 1956). "Mannose isomerase of ... rightleftharpoons } D-fructose Hence, this enzyme has one substrate, D-mannose, and one product, D-fructose. This enzyme ...
Dolichol monophosphate mannose
... is a chemical compound involved in glycosylation. Maeda, Yusuke; Kinoshita, Taroh (2008). " ... "Dolichol-phosphate mannose synthase: Structure, function and regulation". Biochimica et Biophysica Acta (BBA) - General ...
Dolichylphosphate-mannose phosphodiesterase
The enzyme dolichylphosphate-mannose phosphodiesterase (EC 3.1.4.49) catalyzes the reaction dolichyl β-D-mannosyl phosphate + ... H2O ⇌ {\displaystyle \rightleftharpoons } dolichyl phosphate + D-mannose This enzyme belongs to the family of hydrolases, ...
Mannose 6-phosphate
I-cell disease Insulin-like growth factor 2 receptor Mannose Mannose 1-phosphate Alberts, Bruce; et al. (2002). Molecular ... Mannose-6-phosphate (M6P) is a molecule bound by lectin in the immune system. M6P is converted to fructose 6-phosphate by ... Mannose-6-Phosphate+Receptor at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Role of M6P in protein ... There, the M6P moiety is recognized and bound by mannose 6-phosphate receptor (MPR) proteins at pH 6.5-6.7. The M6P-tagged ...
Guanosine diphosphate mannose
GDP-mannose is essential in eukaryotes. GDP-mannose is produced from GTP and mannose-6-phosphate by the enzyme mannose-1- ... Guanosine diphosphate mannose or GDP-mannose is a nucleotide sugar that is a substrate for glycosyltransferase reactions in ... One of the enzymes from the family of nucleootidyl-transferases, GDP-Mannose Pyrophosphorylase (GDP-MP) is an pervasive enzyme ... Pomel, Sébastien; Mao, Wei; Ha-Duong, Tâp; Cavé, Christian; Loiseau, Philippe M. (2019-05-31). "GDP-Mannose Pyrophosphorylase: ...
Mannose phosphate isomerase
... and mannose-6-phosphate (M6P). Mannose-6-phosphate isomerase may also enable the synthesis of GDP-mannose in eukaryotic ... Because mannose and glucose are stereoisomers at C2, which is crucial to the mechanism for both enzymes, PMI must allow extra ... Mannose-6 phosphate isomerase (MPI), alternately phosphomannose isomerase (PMI) (EC 5.3.1.8) is an enzyme which facilitates the ... MPI must convert an aldose (mannose) to a ketose (fructose), in addition to opening and closing the rings for these sugars. In ...
Mannose-1-phosphate guanylyltransferase
... diphospho-D-mannose, pyrophosphorylase), GDP-mannose pyrophosphorylase, guanosine 5'-diphospho-D-mannose pyrophosphorylase, ... GDP-mannose Thus, the two substrates of this enzyme are GTP and alpha-D-mannose 1-phosphate, whereas its two products are ... alpha-D-mannose-1-phosphate guanylyltransferase. Other names in common use include GTP-mannose-1-phosphate guanylyltransferase ... and mannose 1-phosphate guanylyltransferase (guanosine triphosphate). This enzyme participates in fructose and mannose ...
GDP-mannose 6-dehydrogenase
In enzymology, a GDP-mannose 6-dehydrogenase (EC 1.1.1.132) is an enzyme that catalyzes the chemical reaction GDP-D-mannose + 2 ... and guanosine diphospho-D-mannose dehydrogenase. This enzyme participates in fructose and mannose metabolism. This protein may ... The systematic name of this enzyme class is GDP-D-mannose:NAD+ 6-oxidoreductase. Other names in common use include guanosine ... 2 H+ The 3 substrates of this enzyme are GDP-D-mannose, NAD+, and H2O, whereas its 3 products are GDP-D-mannuronate, NADH, and ...
Mannose 6-phosphate receptor
... mannose 6-phosphate) or phosphodiester (Man-phosphate-GlcNAc) Number of mannose 6-phosphate tags Location of the mannose 6- ... Domains 3, 5 and 9 have been found to bind to mannose 6-phosphate. Domains 3 and 9 can bind to mannose 6-phosphate with high ... Each monomer forms a 9 stranded β-barrel which can bind to a single mannose 6-phosphate residue. The CI-MPR and CD-MPR bind ... Mannose 6-phosphate receptors bind newly synthesized lysosomal hydrolases in the trans-Golgi network (TGN) and deliver them to ...
Mannose receptor C-type 1
... is a protein that in humans is encoded by the MRC1 gene. The recognition of complex carbohydrate ... "Entrez Gene: Mannose receptor C-type 1". Retrieved 2018-10-15. DesJardin LE, Kaufman TM, Potts B, Kutzbach B, Yi H, Schlesinger ... Le Cabec V, Emorine LJ, Toesca I, Cougoule C, Maridonneau-Parini I (June 2005). "The human macrophage mannose receptor is not a ... The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and ...
GDP-mannose 3,5-epimerase
The systematic name of this enzyme class is GDP-mannose 3,5-epimerase. Other names in common use include GDP-D-mannose:GDP-L- ... In enzymology, a GDP-mannose 3,5-epimerase (EC 5.1.3.18) is an enzyme that catalyzes the chemical reaction GDP-mannose ⇌ {\ ... GDP-mannose, and two products, GDP-L-galactose and GDP-L-gulose Since only GDP-L-gulose (the C5-epimer of GDP-D-mannose) was ... Gevaert O, Van Overtveldt S, Da Costa M, Beerens K, Desmet T (2020). "GDP-altrose as novel product of GDP-mannose 3,5-epimerase ...
GDP-mannose 4,6-dehydratase
The chemical reaction of GDP-Mannose 4, 6-Dehydratase is as shown: GDP-mannose ↔ GDP-4-dehydro-6-deoxy-D-mannose + H2O The ... GDP-D-mannose dehydratase, GDP-D-mannose 4,6-dehydratase, GMD, and GDP-mannose 4,6-hydro-lyase. The enzyme is a part of the GDP ... GDP-D-mannose dehydratase, GDP-D-mannose 4,6-dehydratase, Gmd, and GDP-mannose 4,6-hydro-lyase. This enzyme participates in ... The enzyme GDP-Mannose 4, 6-Dehydratase is only present in one pathway that we know of. This pathway is the GDP-mannose- ...
Mannose-1-phosphate guanylyltransferase (GDP)
GDP mannose phosphorylase Mannose 1-phosphate (guanosine diphosphate) guanylyltransferase GDP mannose phosphorylase GDP-mannose ... GDP-mannose Thus, the two substrates of this enzyme are GDP and alpha-D-mannose 1-phosphate, whereas its two products are ... alpha-D-mannose-1-phosphate guanylyltransferase. This enzyme participates in fructose and mannose metabolism. ... In enzymology, a mannose-1-phosphate guanylyltransferase (GDP) (EC 2.7.7.22) is an enzyme that catalyzes the chemical reaction ...
PTS Mannose-Fructose-Sorbose Family
The mannose porter of Escherichia coli, for example, can transport and phosphorylate glucose, mannose, fructose, glucosamine, N ... The PTS Mannose-Fructose-Sorbose (Man) Family (TC# 4.A.6) is a group of multicomponent PTS systems that are involved in sugar ... As of this edit, this article uses content from "4.A.6 The PTS Mannose-Fructose-Sorbose (Man) Family", which is licensed in a ... Huber, F.; Erni, B. (1996-08-01). "Membrane topology of the mannose transporter of Escherichia coli K12". European Journal of ...
Mannose-6-phosphate 6-reductase
Other names in common use include NADPH-dependent mannose 6-phosphate reductase, mannose-6-phosphate reductase, 6- ... In enzymology, a mannose-6-phosphate 6-reductase (EC 1.1.1.224) is an enzyme that catalyzes the chemical reaction D-mannitol 1- ... and NADPH-mannose-6-P reductase. Rumpho ME, Edwards GE, Loescher WH (1983). "A pathway for photosynthetic carbon flow to ... whereas its 3 products are D-mannose 6-phosphate, NADPH, and H+. This enzyme belongs to the family of oxidoreductases, ...
Dolichyl-phosphate-mannose-protein mannosyltransferase
The systematic name of this enzyme class is dolichyl-phosphate-D-mannose:protein O-D-mannosyltransferase. Other names in common ... In enzymology, a dolichyl-phosphate-mannose-protein mannosyltransferase (EC 2.4.1.109) is an enzyme that catalyzes the chemical ... the two substrates of this enzyme are dolichyl phosphate D-mannose and protein, whereas its two products are dolichyl phosphate ... "Yeast mannosyl transferases requiring dolichyl phosphate and dolichyl phosphate mannose as substrate. Partial purification and ...
Mannose-binding protein-associated serine protease
... are serine proteases involved in the complement system. Types include: MASP1 ... "The emerging roles of mannose-binding lectin-associated serine proteases (MASPs) in the lectin pathway of complement and beyond ... "Molecular characterization of a novel serine protease involved in activation of the complement system by mannose-binding ...
Cation-dependent mannose-6-phosphate receptor
cation-dependent+mannose-6-phosphate+receptor at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e ( ... Kölsch H, Ptok U, Majores M, Schmitz S, Rao ML, Maier W, Heun R (2004). "Putative association of polymorphism in the mannose 6- ... The CD-MPR is one of two transmembrane proteins that bind mannose-6-phosphate (M6P) tags on acid hydrolase precursors in the ... Ghosh P, Dahms NM, Kornfeld S (March 2003). "Mannose 6-phosphate receptors: new twists in the tale". Nat. Rev. Mol. Cell Biol. ...
GDP-mannose:cellobiosyl-diphosphopolyprenol alpha-mannosyltransferase
GDP-mannose:cellobiosyl-diphosphopolyprenol+alpha-mannosyltransferase at the U.S. National Library of Medicine Medical Subject ... GDP-mannose:cellobiosyl-diphosphopolyprenol alpha-mannosyltransferase (EC 2.4.1.252, GumH, AceA, alpha1,3-mannosyltransferase ... Petroni EA, Ielpi L (August 1996). "Isolation and nucleotide sequence of the GDP-mannose:cellobiosyl-diphosphopolyprenol alpha- ... This enzyme catalyses the following chemical reaction GDP-mannose + D-Glc-beta-(1->4)-Glc-alpha-1-diphospho-ditrans,octacis- ...
GDP-4-dehydro-6-deoxy-D-mannose reductase
GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+ The 3 substrates of this enzyme are GDP-6-deoxy-D-mannose, NAD+, and NADP+, ... In enzymology, a GDP-4-dehydro-6-deoxy-D-mannose reductase (EC 1.1.1.281) is an enzyme that catalyzes the chemical reaction GDP ... The systematic name of this enzyme class is GDP-6-deoxy-D-mannose:NAD(P)+ 4-oxidoreductase (D-rhamnose-forming). Other names in ... This enzyme participates in fructose and mannose metabolism. Messner P; Graninger, M; Adam, G; Puchberger, M; Kosma, P; Zayni, ...
High-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase
... the core mannose of high-mannose oligosaccharides produced by Dictyostelium discoideum The activity of the intersecting mannose ... High-mannose-oligosaccharide+beta-1,4-N-acetylglucosaminyltransferase at the U.S. National Library of Medicine Medical Subject ... High-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase (EC 2.4.1.197), uridine diphosphoacetylglucosamine- ... high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase) is an enzyme with systematic name UDP-N-acetyl-D- ...
Enantioselective synthesis
Fischer, Emil; Hirschberger, Josef (1 January 1889). "Ueber Mannose. II". Berichte der Deutschen Chemischen Gesellschaft. 22 (1 ...
Pattern recognition receptor
Another potential characterization of the CLRs can be into mannose receptors and asialoglycoprotein receptors. The mannose ... Specifically, mannose binding triggers recruitment of MBL-associated serine proteases (MASPs). The serine proteases activate ... It recognizes and binds to repeated mannose units on the surfaces of infectious agents and its activation triggers endocytosis ... Dommett RM, Klein N, Turner MW (September 2006). "Mannose-binding lectin in innate immunity: past, present and future". Tissue ...
MBL deficiency
"Mannose-binding lectin deficiency". Genetics Home Reference. U.S. National Library of Medicine. v t e (Articles with short ...
Fibronectin type II domain
... cation-independent mannose-6-phosphate receptor; mannose receptor of macrophages; 180 Kd secretory phospholipase A2 receptor; ... Drickamer K, Taylor ME, Conary JT, Lennartz MR, Stahl PD (1990). "Primary structure of the mannose receptor contains multiple ... Kornfeld S (1992). "Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptors". Annu. Rev. ...
Agnes Marion Moodie
Irvine, James Colquhoun; Moodie, Agnes Marion (1905). "CXLIV.-The alkylation of mannose". J. Chem. Soc., Trans. 87: 1462-1468. ...
Glycan
... cation-independent mannose-6-phosphate receptor) and CD-MPR (cation-dependent mannose-6-phosphate receptor). In eukaryotes, O- ... Five mannose residues are then added to this structure. At this point, the partially finished core glycan is flipped across the ... The modification of an N-linked glycan with a mannose-6-phosphate residue serves as a signal that the protein to which this ... This core structure of N-linked glycans, thus, consists of 14 residues (3 glucose, 9 mannose, and 2 N-acetylglucosamine). Image ...
Pancreatic islet macrophage
... mannose receptor), CD301, CD103. The mesoderm gives rise to myeloid progenitor cells, which further differentiate into ...