Hypertriglyceridemia
... "secondary hypertriglyceridemia") or whether no such underlying cause exists ("primary hypertriglyceridaemia"). There is a ... "secondary hypertriglyceridemia") or whether no such underlying cause exists ("primary hypertriglyceridaemia"). There is a ... Hypertriglyceridemia is the presence of high amounts of triglycerides in the blood. Triglycerides are the most abundant fatty ... Hypertriglyceridemia itself is usually symptomless, although high levels may be associated with skin lesions known as xanthomas ...
Familial hypertriglyceridemia
... falls in the Fredrickson-Levy and Lee's (FLL) phenotypes. The phenotypes include types I, IIa, ... Familial hypertriglyceridemia is considered to be inherited in an autosomal dominant manner. However, it is important to ... Familial hypertriglyceridemia is considered a type IV familial dyslipidemia it is distinguished from other dyslipidemias based ... Treatment for familial hypertriglyceridemia should focus primarily on reducing serum triglyceride levels. If an individual has ...
Dyslipidemia
Rosenson, Robert S; Eckel, Robert H (April 9, 2021). "Hypertriglyceridemia". UpToDate. Retrieved April 21, 2021. Wilson, Peter ... familial hypertriglyceridemia, combined hyperlipidemia, and HDL-C metabolism disorders. In familial hypercholesterolemia, a ... "Icosapent ethyl for the treatment of severe hypertriglyceridemia". Therapeutics and Clinical Risk Management. 10: 485-492. doi: ... "Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia". New England Journal of Medicine. 380 (1): 11-22. ...
Hyperlipidemia
Pejic RN, Lee DT (2006-05-01). "Hypertriglyceridemia". Journal of the American Board of Family Medicine. 19 (3): 310-316. doi: ... They may result in increased risk of premature atherosclerosis or, when associated with marked hypertriglyceridemia, may lead ... It is associated with hypercholesterolemia (typically 8-12 mmol/L), hypertriglyceridemia (typically 5-20 mmol/L), a normal ApoB ... The receptor defect is an autosomal recessive mutation or polymorphism.[citation needed] Familial hypertriglyceridemia is an ...
Ethyl eicosapentaenoic acid
It is used in combination with changes in diet in adults with hypertriglyceridemia ≥ 150 mg/dL. Further, it is often required ... September 2019). "Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: A Science Advisory From the American Heart ... Weintraub HS (November 2014). "Overview of prescription omega-3 fatty acid products for hypertriglyceridemia". Postgraduate ... Sweeney ME (14 April 2015). Khardori R (ed.). "Hypertriglyceridemia Pharmacologic Therapy". Medscape Drugs & Diseases. Archived ...
Laboratory Syrian hamster
Gotto AM, Jr (14 December 1992). "Hypertriglyceridemia: risks and perspectives". The American Journal of Cardiology. 70 (19): ... basic mechanisms underlying the common hypertriglyceridemia and low HDL cholesterol levels". Diabetes. 45 Suppl 3: S27-30. doi: ...
Familial partial lipodystrophy
Insulin resistance and hypertriglyceridemia occur. Calf muscular hypertrophy may occur. Type 5 is due to mutations in the AKT2 ... The patients also had hypertension, insulin resistance and hypertriglyceridemia. Type 6 due to mutations in the CIDEC gene. It ... Complications include hypertension, insulin resistance and hypertriglyceridemia. The gene causing this condition is not yet ... Other conditions associated with this condition include acanthosis nigricans, fatty liver, hypertriglyceridemia and polycystic ...
Lipid-lowering agent
Fibrates are indicated for hypertriglyceridemia. Fibrates typically lower triglycerides by 20% to 50%. Level of the good ...
Zieve's syndrome
Leslie Zieve described patients with a combination of alcoholic liver disease, hemolytic anemia and hypertriglyceridemia.[ ... "Zieveʼs Syndrome Presenting With Severe Hypertriglyceridemia". ACG Case Reports Journal. 6 (7): 1-3. doi:10.14309/crj. ... may require plasmapharesis to avoid complications associated with hypertriglyceridemia. Zieve's syndrome was initially ...
Prediabetes
Reaven GM, Lerner RL, Stern MP, Farquhar JW (November 1967). "Role of insulin in endogenous hypertriglyceridemia". The Journal ...
Canine pancreatitis
"Investigation of Hypertriglyceridemia in Healthy Miniature Schnauzers". Journal of Veterinary Internal Medicine. doi:10.1111/j. ...
Hyperglycerolemia
Hypertriglyceridemia U.S. Department of Health & Human Services (n.d.), Genetic and Rare Diseases Information Center. Retrieved ... This condition is known as pseudo-hypertriglyceridemia, a falsely elevated condition of triglycerides. Another group treated ... a pseudo-hypertriglyceridemia: a case report]. In Anales de pediatria (Barcelona, Spain: 2003) (Vol. 71, No. 1, pp. 68-71) ... Pseudo-hypertriglyceridaemia or hyperglycerolemia?. Clínica e Investigación en Arteriosclerosis, 25(3), 123-126. Orphanet (n.d ...
Hepatic lipase
Chatterjee C, Sparks DL (April 2011). "Hepatic lipase, high density lipoproteins, and hypertriglyceridemia". The American ...
CANDLE syndrome
Other possible conditions are hypertriglyceridemia and lipodystrophy. Other novel mutations resulting in the syndrome have also ...
Eicosapentaenoic acid
... relative to a placebo in those with statin-resistant hypertriglyceridemia. EPA is obtained in the human diet by eating oily ... "Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia". New England Journal of Medicine. 380 (1): 11-22. ...
Statin
Kushner PA, Cobble ME (November 2016). "Hypertriglyceridemia: the importance of identifying patients at risk". Postgraduate ...
Lipaemia retinalis
... occurs commonly with familial hypertriglyceridaemia, and rarely with combined hypertriglyceridaemia. ... Lipaemia retinalis is a retinal disease caused by hypertriglyceridemia or chylomicronemia. Depending on plasma triglyceride ... hypertriglyceridemia) or Lipoprotein lipase deficiency (chylomicronemia). In this condition the retinal arteries and veins, and ... retinal signs of LR are an important clinical sign of hypertriglyceridemia. Vinger and Sachs classified lipaemia retinalis into ...
Pancreatic disease
Less frequent but important causes are hypertriglyceridemia, drugs, infections. Chronic pancreatitis is a long-standing ...
Combined hyperlipidemia
Chronic, excessive alcohol use increases the risk of hypertriglyceridemia. Smoking and not exercising may lead to ... Other disorders, such as diabetes mellitus, kidney disease, and hypothyroidism, may promote hypertriglyceridemia. Certain drugs ... may cause hypertriglyceridemia. Obesity increases the risk of hyperlipidemia. ...
Omega-3 acid ethyl esters
Hypertriglyceridemia Pharmacologic Therapy for Medscape Drugs & Diseases, Ed. Khardori R. Updated: Apr 14, 2015, page accessed ... Karalis DG (February 2017). "A Review of Clinical Practice Guidelines for the Management of Hypertriglyceridemia: A Focus on ... Weintraub HS (November 2014). "Overview of prescription omega-3 fatty acid products for hypertriglyceridemia". Postgraduate ... hypertriglyceridemia. In the European Union and other major markets outside the US, omega-3 acid ethyl esters are indicated for ...
TMEM112
"Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia". Nat Genet. 39 (12): 1483-1487. doi:10.1038 ...
Lipodystrophy
Patients display hypertriglyceridemia, severe fatty liver disease and little or no adipose tissue. Average patient lifespan is ... The absence of fat tissue is associated with insulin resistance, hypertriglyceridemia, non-alcoholic fatty liver disease (NAFLD ... "Antisense Inhibition of Apolipoprotein C-III in Patients with Hypertriglyceridemia". The New England Journal of Medicine. 373 ( ...
ANGPTL8
Inhibition of ANGPTL8 represents a possible therapeutic strategy for hypertriglyceridemia. GRCh38: Ensembl release 89: ...
Omega-3 carboxylic acids
Hypertriglyceridemia Pharmacologic Therapy for Medscape Drugs & Diseases, Ed. Khardori R. Updated: Apr 14, 2015, page accessed ... 2019). "Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: A Science Advisory From the American Heart Association ... Clinical trials of Epanova for severe hypertriglyceridemia showed good results. However, a clinical trial on mixed ... Weintraub, HS (2014). "Overview of prescription omega-3 fatty acid products for hypertriglyceridemia". Postgrad Med. 126 (7): 7 ...
Omega-3 fatty acid
September 2019). "Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: A Science Advisory From the American Heart ... Weintraub HS (November 2014). "Overview of prescription omega-3 fatty acid products for hypertriglyceridemia". Postgraduate ...
David J. Galton
This can affect expression of the resulting phenotype of hypertriglyceridemia. His laboratory was one of the first to use ... Stocks, J; Holdsworth, G; Galton, DJ (1979). "Hypertriglyceridaemia associated with an abnormal triglyceride-rich lipoprotein ... such as hypertriglyceridemia and atherosclerosis. This led eventually to the development of Genome Wide Association Studies ( ... relation to hypertriglyceridaemia". Lancet. 2 (8322): 444-446. doi:10.1016/s0140-6736(83)91440-x. PMID 6131168. S2CID 29511911 ...
Xanthoma
Digby M, Belli R, McGraw T, Lee A (January 2011). "Eruptive xanthomas as a cutaneous manifestation of hypertriglyceridemia: a ...
Acute pancreatitis
Rawla P, Sunkara T, Thandra KC, Gaduputi V (December 2018). "Hypertriglyceridemia-induced pancreatitis: updated review of ... and hypertriglyceridemia. Reasons for false positive elevated serum amylase include salivary gland disease (elevated salivary ... hypertriglyceridemia Respiratory Hypoxemia, atelectasis, effusion, pneumonitis, acute respiratory distress syndrome Renal Renal ... pancreas divisum Radiotherapy Autoimmune pancreatitis Severe hypertriglyceridemia Scorpion venom Chinese liver fluke Ischemia ...
Glycerol-3-phosphate dehydrogenase 1
Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants ... and hypertriglyceridemia". Eur. J. Hum. Genet. 22 (10): 1229-32. doi:10.1038/ejhg.2014.8. PMC 4169545. PMID 24549054. This ... "Transient infantile hypertriglyceridemia, fatty liver, and hepatic fibrosis caused by mutated GPD1, encoding glycerol-3- ...
Pancreatitis
Birth control pills and HRT cause arterial thrombosis of the pancreas through the accumulation of fat (hypertriglyceridemia). ... Meanwhile, thiazide diuretics cause hypertriglyceridemia and hypercalcemia, where the latter is the risk factor for pancreatic ... Rawla P, Sunkara T, Thandra KC, Gaduputi V (December 2018). "Hypertriglyceridemia-induced pancreatitis: updated review of ...