Ota Y, Mariash A, Wagner JL, Mariash CN (1997). "Cloning, expression and regulation of the human S14 gene". Mol. Cell. ... a metabolic integrator in normal and neoplastic cells". Thyroid. 8 (9): 815-25. doi:10.1089/thy.1998.8.815. PMID 9777755. ... The protein encoded by this gene is similar to the gene product of S14, a rat gene whose expression is limited to liver and ... "Common prefrontal cortical gene expression profiles between adolescent SHR/NCrl and WKY/NCrl rats which showed inattention ...
... gene expression regulation, fungal MeSH G05.315.370 - gene expression regulation, neoplastic MeSH G05.315.370.500 - gene ... gene expression regulation, plant MeSH G05.315.385 - gene expression regulation, viral MeSH G05.315.410 - gene silencing MeSH ... gene amplification MeSH G05.315.290 - gene expression regulation, archaeal MeSH G05.315.300 - gene expression regulation, ... gene expression regulation, developmental MeSH G05.315.320 - gene expression regulation, enzymologic MeSH G05.315.320.200 - ...
Wilson PM, Fazzone W, LaBonte MJ, Lenz HJ, Ladner RD (Jan 2009). "Regulation of human dUTPase gene expression and p53-mediated ... "dUTP nucleotidohydrolase isoform expression in normal and neoplastic tissues: association with survival and response to 5- ... Notably, DUT expression is regulated by the tumor suppressor gene p53 in order to promote apoptosis of tumor cells.. Abnormal ... DUTP pyrophosphatase, also known as DUT, is an enzyme which in humans is encoded by the DUT gene on chromosome 15. This gene ...
Down regulation of the PAX gene expression inhibits cell growth and induces apoptosis. This could be a possible avenue for ... Expression of PAX8 is increased in neoplastic renal tissues, Wilms tumors, ovarian cancer and Müllerian carcinomas. For this ... Paired box gene 8, also known as PAX8, is a protein which in humans is encoded by the PAX8 gene. This gene is a member of the ... "Entrez Gene: PAX8 paired box gene 8". "PAX8 gene". Genetics Home Reference. 2016-03-28. Retrieved 2016-04-05. Laury AR, Perets ...
Lindsten T, June CH, Thompson CB, Leiden JM (1989). "Regulation of 4F2 heavy-chain gene expression during normal human T-cell ... a type II membrane glycoprotein involved in normal and neoplastic cell growth". Proc. Natl. Acad. Sci. U.S.A. 84 (18): 6526-30 ... 4F2hc/CD98 heavy subunit protein encoded by the SLC3A2 gene (this gene) CD98 light subunit protein encoded by the SLC7A5 gene ... "Isolation and structural characterization of the human 4F2 heavy-chain gene, an inducible gene involved in T-lymphocyte ...
... are currently defined by the expression of the EWSR1-SMAD3 fusion gene in their neoplastic cells. Epithelioid and spindle cell ... the processing of micro-RNAs that are involved in RNA silencing and post-transcriptional regulation of gene expression; and 3) ... or FEV gene). These fusion genes are the EWSR1-FLI1 fusion gene in 80-85% of cases or EWSR1-ERG fusion gene in 5 to 10% of ... express fusion genes composed of an FET family gene fused to a gene that is not a ETS transcription family gene. These fusion ...
"Global Analysis of Mouse Polyomavirus Infection Reveals Dynamic Regulation of Viral and Host Gene Expression and Promiscuous ... In MPyV, MTag is an efficient oncoprotein that can be sufficient to induce neoplastic transformation in some cells. The genes ... MTag plays a role in viral DNA replication and in the transition from early to late gene expression, and its absence can cause ... The LTag gene is usually encoded in two exons, of which the first overlaps with the genes for STag and MTag. The result of this ...
"Gastrin gene expression in human pancreatic and colon cancers". Gastroenterology. 108 (4): A1246. April 1995. doi:10.1016/0016- ... 2005: Ras and β-catenin/Tcf4 pathways induce synergistic activation of the GAST gene, contributing to possible neoplastic ... 2003: hPG80 is involved in the dissociation regulation of adherent and tight junctions. Src mediates the effects of hPG80 on ... Singh, P.; Owlia, A.; Varro, A.; Dai, B.; Rajaraman, S.; Wood, T. (1996-09-15). "Gastrin gene expression is required for the ...
Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and ... S100 proteins are localized in the cytoplasm and nucleus of a wide range of cells, and involved in the regulation of a number ... Peña LA, Brecher CW, Marshak DR (1997). "beta-Amyloid regulates gene expression of glial trophic substance S100 beta in C6 ... S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at ...
Schlegel J, Güneysu S, Mennel HD (2002). "Expression of the genes of methyl-binding domain proteins in human gliomas". Oncol. ... A majority of histologically normal fields surrounding the neoplastic growths also show reduced MBD4 mRNA expression (a field ... A mutational deficiency in MBD4 causes down-regulation, at the protein level, of MMR proteins Mlh1, Msh2, Pms2, and Msh6 by 5.8 ... Mutations in the MBD4 gene (especially expansions/deletions in the polyadenine regions of the MBD4 gene) increase the genomic ...
Ellmeier W, Aguzzi A, Kleiner E, Kurzbauer R, Weith A (Aug 1992). "Mutually exclusive expression of a helix-loop-helix gene and ... Deed RW, Hara E, Atherton GT, Peters G, Norton JD (1997). "Regulation of Id3 cell cycle function by Cdk-2-dependent ... helix transcription factors Id1 and Id3 have a functional role in control of cell division in human normal and neoplastic ... Deed RW, Jasiok M, Norton JD (1998). "Lymphoid-specific expression of the Id3 gene in hematopoietic cells. Selective antagonism ...
Bamba N, Chano T, Taga T, Ohta S, Takeuchi Y, Okabe H (Oct 2004). "Expression and regulation of RB1CC1 in developing murine and ... "RB1CC1 suppresses cell cycle progression through RB1 expression in human neoplastic cells". International Journal of Molecular ... "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) ... characterization and mapping of the mouse and human RB1CC1 genes". Gene. 291 (1-2): 29-34. doi:10.1016/S0378-1119(02)00585-1. ...
Articles with short description, Short description matches Wikidata, Chromosomal abnormalities, Mutated genes, Gene expression ... Huh HD, Kim DH, Jeong HS, Park HW (June 2019). "Regulation of TEAD Transcription Factors in Cancer Biology". Cells. 8 (6): 600 ... It is generally accepted that the BRD4-NUT protein promotes these neoplasms by maintaining their neoplastic cells in a ... A fusion gene is an abnormal gene consisting of parts from two different genes that form as a result of a large scale gene ...
Chen, Hong Ping; Zhao, Yu Tina; Zhao, Ting C (2015). "Histone Deacetylases and Mechanisms of Regulation of Gene Expression ( ... "Histone deacetylase inhibitors as anti-neoplastic agents". Cancer Letters. 280 (2): 192-200. doi:10.1016/j.canlet.2009.03.013. ... November 2006). "Negative and positive regulation of gene expression by mouse histone deacetylase 1". Molecular and Cellular ... ko05220 Histone acetylation plays an important role in the regulation of gene expression. Hyperacetylated chromatin is ...
"Gene expression changes in progression of cervical neoplasia revealed by microarray analysis of cervical neoplastic ... molecular characterization and regulation of expression". Toxicol. Appl. Pharmacol. 125 (1): 1-6. doi:10.1006/taap.1994.1042. ... FMO4 gene has been observed progressively downregulated in Human papillomavirus-positive neoplastic keratinocytes derived from ... "Quantification and cellular localization of expression in human skin of genes encoding flavin-containing monooxygenases and ...
"Gene expression of the human prostaglandin E receptor EP4 subtype: differential regulation in monocytoid and lymphoid lineage ... a possible autocrine/paracrine regulation of neoplastic cell function via EP2/EP4 receptors". The Journal of Clinical ... Activation of ERK induces expression of EGR1, a transcription factor which controls transcription of genes involved in cellular ... Activated CREB stimulates the expression of genes such as c-fos, somatostatin, and corticotropin-releasing hormone that ...
Its expression is seen in the neural tube much later than other ID genes. ID4 was also shown to be involved in the regulation ... the ID4 gene has been shown to be expressed in the neoplastic astrocytes but not expressed in the neoplastic oligodendrocytes. ... the family of ID genes are seen to be significantly increased in expression. The ID4 gene is also known as DNA-binding protein ... The ID4 gene is part of the ID gene family. This family is also known as inhibitors of DNA binding protein family and are ...
"Comparative assessment expression of the inhibitor of growth 1 gene (ING1) in normal and neoplastic tissues". Hybridoma and ... "Role of the Sin3-histone deacetylase complex in growth regulation by the candidate tumor suppressor p33(ING1)". Molecular and ... Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced ... Inhibitor of growth protein 1 is a protein that in humans is encoded by the ING1 gene. This gene encodes a tumor suppressor ...
SART1 is known to play a role in mRNA splicing and appears to play a role in hypoxia-induced regulation of EPO gene expression ... Expression of ETS1was increased in cancer tissues as compared with the expression in corresponding non-neoplastic tissues. ... which appears to play a role in hypoxia-induced regulation of EPO gene expression. C1orf198 has been found to be associated ... Wang Z, Chen G, Wang Q, Lu W, Xu M (September 2017). "Identification and validation of a prognostic 9-genes expression ...
The Laboratory of Molecular Immunogenetics conducts research on B lymphocytes focusing on the regulation of gene expression and ... The Dermatology Branch investigates fundamental and clinical aspects of neoplastic and inflammatory skin disease as well as ... A major focus is the study of receptor-mediated signal transduction and how these processes link to the regulation of genes ... The Laboratory of Muscle Stem Cells and Gene Regulation investigates the cellular and molecular mechanisms that regulate ...
Several genetic alterations in SEF neoplastic cells are fusion genes. A fusion gene is a hybrid gene formed from two previously ... The EWSR1 and FUS gene product proteins belong to the FET protein family of proteins which regulate gene expression as well as ... The YAP1 gene product, yes-associated protein, contributes to the regulation of cell proliferation and apoptosis, i.e. ... A smaller study found the EWSR1-CREB3L1 fusion gene in the neoplastic cells of 3 of 8 and EWSR1 gene rearrangements in 2 of 8 ...
Gene Structure and Expression. 1446 (3): 213-24. doi:10.1016/s0167-4781(99)00090-1. PMID 10524196. Bühring HJ, Seiffert M, ... the measurement of CD203c up-regulation is as reliable as CD63 expression in the diagnosis of cat allergy". Journal of ... in inflammatory and neoplastic bile duct diseases". Cancer Letters. 207 (2): 139-47. doi:10.1016/j.canlet.2003.11.002. PMID ... Expression of the related rat mRNA has been found in a subset of immature glial cells and in the alimentary tract. The ...
One key factor in healing is the regulation of cytokine gene expression, which enables complementary groups of cells to respond ... These early neoplastic changes must be distinguished from hyperplasia, a reversible increase in cell division caused by an ... In either case, expression of these genes promotes the malignant phenotype of cancer cells. Tumor suppressor genes are genes ... reduced or absent expression of DNA repair genes is due to epigenetic alterations that reduce or silence gene expression. This ...
The gene, CDC7, is involved in the regulation of cell cycle because of the gene product Cdc7 kinase. The protein is expressed ... Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Additional transcript ... There are several ways its expression can be altered that leads to problems. In mouse embryonic stem cells (ESCs), Cdc7 is ... The Cdc7 kinase is involved in regulation of the cell cycle at the point of chromosomal DNA replication. The gene CDC7 appears ...
... a mechanism for the regulation of Blimp-1 expression and B lymphocyte differentiation by the B cell lymphoma-6 protooncogene". ... "The lineage-defining factors T-bet and Bcl-6 collaborate to regulate Th1 gene expression patterns". The Journal of Experimental ... It is often used together with antibodies to Bcl-2 antigen to distinguish neoplastic follicles from those found in benign ... Transcriptional regulation of BCL6 is vast and complex, but many of the outcomes of BCL6's transcriptional regulation on TFH ...
"Uroplakin gene expression by normal and neoplastic human urothelium". Am J Pathol. 153 (6): 1957-67. doi:10.1016/S0002-9440(10) ... The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and ... Yuasa T, Yoshiki T, Isono T, Tanaka T, Hayashida H, Okada Y (Sep 1999). "Expression of transitional cell-specific genes, ... Uroplakin-1a (UP1a) is a protein that in humans is encoded by the UPK1A gene. The protein encoded by this gene is a member of ...
... expression in various organs in vivo and its regulation in vitro". Leukemia. 11 (Suppl 3): 145-6. PMID 9209324. Andersson AC, ... "Entrez Gene: ERV3 endogenous retroviral sequence 3 (includes zinc finger protein H-plk/HPF9)". Jern P, Coffin JM (December 2008 ... mRNA in normal and neoplastic tissues". International Journal of Oncology. 12 (2): 309-13. doi:10.3892/ijo.12.2.309. PMID ... HERV-R_7q21.2 provirus ancestral envelope (Env) polyprotein is a protein that in humans is encoded by the ERV3 gene. The human ...
"Retinol-regulated gene expression in human tracheobronchial epithelial cells. Enhanced expression of elongation factor EF-1 ... These effects may be attributed to the resulting down-regulation of the PI3K/Akt/NF-κB and PI3K/Akt/mTOR signaling pathways. ... combined with altered levels of eEF1A-derived bacterial peptides in neoplastic disease, may lead to autoimmunity in breast ... Zheng C, Baum BJ (2014). "All human EF1α promoters are not equal: markedly affect gene expression in constructs from different ...
... expression marks slowly cycling intestinal stem cells". Proceedings of the National Academy of Sciences. 108 (1): 179-184. doi: ... "Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling". Nature Cell Biology. 14 (4): 401- ... "Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation". Nature. 457 (7229): 603-607. doi: ... "PW1 gene/paternally expressed gene 3 (PW1/Peg3) identifies multiple adult stem and progenitor cell populations". Proceedings of ...
Originally developed for fundamental analysis of factors affecting gene expression, bioreporters were early on applied for the ... 2000) Use of reporter genes for optical measurements of neoplastic disease in vivo. Neoplasia 2 (1-2), 41-52. http://neoreviews ... Kovács KA, Steinmann M, Halfon O, Magistretti PJ, Cardinaux JR (November 2015). "Complex regulation of CREB-binding protein by ... Consequently, turning on the promoter gene now causes the reporter gene to be turned on. Activation of the reporter gene leads ...
Studies of gene expression show that a specific complement of genes, such as follistatin and multiple cyclin kinase inhibitors ... Hyperfunction can occur as a result of hypersecretion, loss of suppression, hyperplastic or neoplastic change, or ... The functional development of the anterior pituitary involves spatiotemporal regulation of transcription factors expressed in ... Studies in mice have shown that interfering with the HOX15 gene can cause parathyroid gland aplasia, which suggests the gene ...