Since the asparagine side-chain can form hydrogen bond interactions with the peptide backbone, asparagine residues are often ... Asparagine synthetase is required for normal development of the brain. Asparagine is also involved in protein synthesis during ... The determination of asparagine's structure required decades of research. The empirical formula for asparagine was first ... The enzyme asparagine synthetase produces asparagine, AMP, glutamate, and pyrophosphate from aspartate, glutamine, and ATP. ...

... can be prepared by refluxing D-glucose with sodium bisulfite in methanol, and then adding L-asparagine, and ... However, this is not due to fructose-asparagine being an essential nutrient, but rather because fructose-asparagine is toxic to ... contributes to fructose-asparagine but not asparagine utilization". Journal of Bacteriology. 199 (22): e00330-17. doi:10.1128/ ... Fructose-asparagine is a aminodeoxysugar. It takes the form of a pale yellow solid. It decomposes above 120 °C. Fructose- ...

... (or aspartate-ammonia ligase) is a chiefly cytoplasmic enzyme that generates asparagine from aspartate. ... This depletion of serum asparagine leads to a subsequent rapid efflux of cellular asparagine, which is immediately acted upon ... In addition, these normal cells are able to upregulate their expression of asparagine synthetase in response to the asparagine ... Hamster BHK ts11 cells produce an inactive asparagine synthetase enzyme, and this loss of asparagine synthetase activity ...

... is synthesized as an inactive zymogen. AEP and other cysteine peptidase are activated when pH changes ... Asparagine endopeptidase (AEP, mammalian legumain, δ-secretase; EC 3.4.22.34) is a proteolytic enzyme from C13 peptidase family ... Gao J, Li K, Du L, Yin H, Tan X, Yang Z (July 2018). "Deletion of asparagine endopeptidase reduces anxiety- and depressive-like ... In humans it is encoded by the LGMN gene (previous symbol PRSC1). It hydrolyzes substrates at the C-terminus of asparagine ...

The catalytic mechanism of the asparagine peptide lyases involves an asparagine residue acting as nucleophile to perform a ... Asparagine peptide lyase are one of the seven groups in which proteases, also termed proteolytic enzymes, peptidases, or ... The main residue of the active site is the asparagine and there are other residues involved in the catalytic mechanism, which ... The C-terminal residue of the intein domain is always an asparagine, which cyclizes to form a succinimide, cleaving its own ...

In enzymology, an asparagine-tRNA ligase (EC 6.1.1.22) is an enzyme that catalyzes the chemical reaction ATP + L-asparagine + ... The systematic name of this enzyme class is L-asparagine:tRNAAsn ligase (AMP-forming). Other names in common use include ... L-asparagine, and tRNA(Asn), whereas its 3 products are AMP, diphosphate, and L-asparaginyl-tRNA(Asn). This enzyme belongs to ... and asparagine translase. This enzyme participates in alanine and aspartate metabolism and aminoacyl-trna biosynthesis. As of ...

a CID 6267 from PubChem (L-asparagine) (Articles with short description, Short description matches Wikidata, PubChem ID (CID) ...

In enzymology, an asparagine-oxo-acid transaminase (EC 2.6.1.14) is an enzyme that catalyzes the chemical reaction L-asparagine ... The systematic name of this enzyme class is L-asparagine:2-oxo-acid aminotransferase. This enzyme is also called asparagine- ... MEISTER A, FRASER PE (1954). "Enzymatic formation of L-asparagine by transamination". J. Biol. Chem. 210 (1): 37-43. PMID ... the two substrates of this enzyme are L-asparagine and 2-oxo acid, whereas its two products are 2-oxosuccinamate and amino acid ...

... asparagine synthetase (glutamine-hydrolysing), glutamine-dependent asparagine synthetase, asparagine synthetase B, AS, AS-B) is ... L-asparagine The enzyme from Escherichia coli has two active sites. Patterson MK, Orr GR (January 1968). "Asparagine ... Asparagine+synthase+(glutamine-hydrolysing) at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: ... Boehlein SK, Richards NG, Schuster SM (March 1994). "Glutamine-dependent nitrogen transfer in Escherichia coli asparagine ...

3-hydroxy-L-asparagine + succinate + CO2 Hypoxia-inducible factor-asparagine dioxygenase contains iron, and requires ascorbate ... Hypoxia-inducible+factor-asparagine+dioxygenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal ... Hypoxia-inducible factor-asparagine dioxygenase (EC 1.14.11.30, HIF hydroxylase) is an enzyme with systematic name hypoxia- ... Lando D, Peet DJ, Whelan DA, Gorman JJ, Whitelaw ML (February 2002). "Asparagine hydroxylation of the HIF transactivation ...

In enzymology, a peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase (EC 3.5.1.52) is an enzyme that catalyzes a chemical ... The systematic name of this enzyme class is N-linked-glycopeptide-(N-acetyl-beta-D-glucosaminyl)-L-asparagine amidohydrolase. ... Tarentino AL, Gómez CM, Plummer TH (Aug 1985). "Deglycosylation of asparagine-linked glycans by peptide:N-glycosidase F". ... asparagine amidase A and its N-glycans". European Journal of Biochemistry. 252 (1): 118-23. doi:10.1046/j.1432-1327.1998. ...

... asparagine mutant". Biochemistry. 36 (46): 13979-88. doi:10.1021/bi971004s. PMID 9369469. Maruyama T, Kitaoka Y, Sachi Y, ...

Kornfeld, Rosalind; Kornfeld, Stuart (1985). "Assembly of Asparagine-Linked Oligosaccharides". Annual Review of Biochemistry. ... Kornfeld, Rosalind; Kornfeld, Stuart (1985). "Assembly of Asparagine-Linked Oligosaccharides". Annual Review of Biochemistry. ...

Other names in common use include asparagine synthetase (ADP-forming), and asparagine synthetase (adenosine diphosphate-forming ... Nair PM (September 1969). "Asparagine synthetase from gamma-irradiated potatoes". Archives of Biochemistry and Biophysics. 133 ... L-asparagine The 3 substrates of this enzyme are ATP, L-aspartate, and NH3, whereas its 3 products are ADP, phosphate, and L- ... asparagine. This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-ammonia ( ...

... on the interior and asparagine (R), Serine (and lysine (K) on the exterior. Asparagine residues may serve as an important ... Kornfeld, R.; Kornfeld, S. (1985). "Assembly of asparagine-linked oligosaccharides" (PDF). Annual Review of Biochemistry. 54: ...

"Entrez Gene: asparagine-linked glycosylation 11". Cipollo, JF; Trimble, RB; Chi, JH; Yan, Q; Dean, N (2001). "The yeast ALG11 ... Asparagine-linked glycosylation protein 11 is an enzyme encoded by the ALG11 gene. Congenital disorder of glycosylation GRCh38 ...

The difucosylation of asparagine-bound N-acetylglucosamine". Eur. J. Biochem. 199 (3): 745-51. doi:10.1111/j.1432-1033.1991. ... The systematic name of this enzyme class is GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of N4 ... asparagine The 5 substrates of this enzyme are GDP-L-fucose, [[N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3 ... asparagine) 3-alpha-L-fucosyl-transferase. Other names in common use include GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,3- ...

It has fewer aspartate, glutamate, and asparagine. The high ratio of basic to acidic amino acids contributes to the protein's ...

This amino acid was replaced with asparagine. The complication with mutations in the BCKDHA gene is that it disrupts the normal ...

The lysine is replaced by an asparagine. The lysine is needed so that the chromophore retinal can covalently bind to the opsin ...

Inhibition of L-'asparagine synthetase in vivo". Biochemical Pharmacology. 25 (16): 1851-8. doi:10.1016/0006-2952(76)90189-1. ... "Reactions of Pseudomonas 7A glutaminase-asparaginase with diazo analogues of glutamine and asparagine result in unexpected ...

Role of histidine 191 and asparagine 194". The Journal of Biological Chemistry. 273 (49): 32753-32762. doi:10.1074/jbc.273.49. ...

Ambasta RK, Ai X, Emerson CP (November 2007). "Quail Sulf1 function requires asparagine-linked glycosylation". The Journal of ...

Other names in common use include asparagine synthetase, and L-asparagine synthetase. This enzyme participates in 3 metabolic ... "Asparagine biosynthesis in Lactobacillus arabinosus and its control by asparagine through enzyme inhibition and repression". J ... Webster GC, Varner JE (1955). "Aspartate metabolism and asparagine synthesis in plant systems". J. Biol. Chem. 215: 91-99. PMID ... L-asparagine The 3 substrates of this enzyme are ATP, L-aspartate, and NH3, whereas its 3 products are AMP, diphosphate, and L- ...

... forms a separate sub-type in the asparagine N-linked glycosylation system. The short paucimannosidic glycans ... Kubelka, Viktoria; Altmann, Friedrich; Mrz, Leopold (February 1995). "The asparagine-linked carbohydrate of honeybee venom ...

50 mg each asparagine, cystine, leucine, and isoleucine; 40 mg lysine hydrochloride; 30 mg serine; 20 mg each aspartic acid, ...

Asparagine and aspartic acid are both larger than threonine, and both asparagine and aspartic acid like to be in a turn while ... Aspartic acid and asparagine carry a formal charge. This charge however is negative for aspartic acid and positive for ... Asparagine and aspartic acid are both hydrophilic, while threonine has intermediate hydrophilicity. ... asparagine. Phoratoxin has not been synthesized in a lab yet. It can, however, be extracted from the Phoradendron. Phoratoxin ...

The least abundant are lysine, methionine, and asparagine. There is less asparagine, isoleucine, and lysine than would be ... Specifically, there is less asparagine, isoleucine, and lysine and more arginine than would be expected for an average protein ...

Chiu M, Taurino G, Bianchi MG, Kilberg MS, Bussolati O (2020-01-09). "Asparagine Synthetase in Cancer: Beyond Acute ...

An N-linked glycoprotein has glycan bonds to the nitrogen containing an asparagine amino acid within the protein sequence. An O ... In N-glycosylation, sugars are attached to nitrogen, typically on the amide side-chain of asparagine. In O-glycosylation, ... For example, inhibition of asparagine-linked, i.e. N-linked, glycosylation can prevent proper glycoprotein folding and full ... method of glycosylation of N-linked glycoproteins is through the reaction between a protected glycan and a protected Asparagine ...