Artemisinins can be used alone, but this leads to a high rate of return of parasites and other drugs are required to clear the ... Artemisinins are not used for malaria prevention because of the extremely short activity (half-life) of the drug. To be ... Artemisinins are generally well tolerated at the doses used to treat malaria. The side effects from the artemisinin class of ... Artemisinins were later found to possess a broad spectrum of activity against a wide range of trematodes, including Schistosoma ...

"Rectal artemisinins rapidly eliminate malarial parasites". EurekAlert!. 2008-03-27. Archived from the original on 3 April 2008 ...

Pacios-Michelena, Anabel; Kasaragod, Vikram Babu; Schindelin, Hermann (2021). "Artemisinins and their impact on inhibitory ... "Elucidating the Molecular Basis for Inhibitory Neurotransmission Regulation by Artemisinins". Neuron. Cell Press. 101 (4): 673- ...

August 2003). "Artemisinins target the SERCA of Plasmodium falciparum". Nature. 424 (6951): 957-961. Bibcode:2003Natur.424.. ...

The consensus is that PfATP6 is a validated target for artemisinins and mammalian SERCA3, in neutrophils, has emerged as a ... August 2003). "Artemisinins target the SERCA of Plasmodium falciparum". Nature. 424 (6951): 957-961. Bibcode:2003Natur.424.. ... Evidence came from a Xenopus oocyte system describing specific interactions between artemisinins and PfATP6 as well as E255L- ... In 2022 it was observed in murine neutrophils that artemisinins were inhibiting migration of these cells. Further investigation ...

Dellicour S, Hall S, Chandramohan D, Greenwood B (February 2007). "The safety of artemisinins during pregnancy: a pressing ... Artemether is an artemisinin derivative and the mechanism of action for artemisinins is.[medical citation needed] Artemether ...

Keiser, J.; Utzinger, J. R. (2007). "Artemisinins and synthetic trioxolanes in the treatment of helminth infections". Current ...

Keiser J, Utzinger J (December 2007). "Artemisinins and synthetic trioxolanes in the treatment of helminth infections". Current ...

The cost of artemisinins limits their use in the developing world. Malaria strains found on the Cambodia-Thailand border are ... Resistance is now common against all classes of antimalarial drugs apart from artemisinins. Treatment of resistant strains ... Artemisinins, discovered by Chinese scientist Tu Youyou and colleagues in the 1970s from the plant Artemisia annua, became the ... to artemisinin monotherapies in subtherapeutic doses for over 30 years and the availability of substandard artemisinins likely ...

They recommend that it be used only when artemisinins are not available. Quinine is also used to treat lupus and arthritis. ...

Artemisinins are sesquiterpene lactones isolated from Artemisia annua, a Chinese traditional medicine. These suppositories are ...

Artesunate is in the class of medications known as artemisinins, which are derivatives from sweet wormwood (Artemisia annua). ... His team, however, demonstrated resistance of Plasmodium falciparum to artemisinins in Western Cambodia. New treatments would ...

The best recognised adverse effect of the artemisinins is that they lower reticulocyte counts. This is not usually of clinical ... It is in the class of medications known as artemisinins, which are derivatives from "qinghao," or sweet wormwood plant ( ... Clark RL (February 2012). "Effects of artemisinins on reticulocyte count and relationship to possible embryotoxicity in ...

The artemisinins became the most potent as well as the safest and most rapidly acting antimalarial drugs, recommended by the ... Weina, PJ (2008). "Artemisinins from folklore to modern medicine--transforming an herbal extract to life-saving drugs". ... For their high efficacy, safety and stability, artemisinins such as artemether and artesunate became the drugs of choice in ... All clinical trials by this time confirmed that artemisinins are more effective than the conventional antimalarial drugs, such ...

Artemisinins and derivatives are proving to be candidates as drugs of choice for trematodiasis. In regions where helminthiasis ...

... evaluation to determine and predict the neurotoxicity of artemisinins". Toxicology. 279 (1-3): 1-9. doi:10.1016/j.tox.2010.09. ...

ISBN 978-7-5046-6996-4. Tu, Y. (2017). From Artemisia annua L. to Artemisinins: The Discovery and Development of Artemisinins ...

The project resulted in the discovery of artemisinins, a class of antimalarial drugs, from the medicinal plant Artemisia annua ...

4-trioxane ring are important potential improvements over the naturally derived artemisinins. The peroxide group in the 1,2,4- ...

... including chloroquine and artemisinins, were used to resist the scourge. Today, artemisinin is present in every remedy applied ...

... traditional Chinese medicine discovered and led to the development of a class of new antimalarial drugs called artemisinins. ...

... artemisinins MeSH D02.455.849.765.424 - farnesol MeSH D02.455.849.765.444 - gossypol MeSH D02.455.849.765.750 - santonin MeSH ... artemisinins MeSH D02.389.338.450 - lipid peroxides MeSH D02.389.338.825 - tert-butylhydroperoxide MeSH D02.389.338.912 - ...