... are several cell lines of mouse embryonic fibroblasts. The original 3T3 cell line (3T3-Swiss albino) was established ... 3T3' cells. Since then, several cell lines have been established with this procotol: 3T3-Swiss albino, the original 1962 cell ... "Sublines of mouse 3T3 cells that accumulate lipid". Cell. 1 (3): 113-116. doi:10.1016/0092-8674(74)90126-3. NIH 3T3 Cell Line ... These cells are also contact inhibited. The cells are sensitive to sarcoma virus and leukemia virus focus formation. 3T3 cells ...

... detects the viability of 3T3 cells after exposure to a chemical in the presence or absence of light. The 3T3 cell line was ... Cell culture can be an alternative to animal use in some cases. For example, cultured cells have been developed to create ... Tumoroids-3D cell cultures derived from cells biopsied from human patients-can be used in studying the genomics and drug ... "NIH3T3 General Information". NIH 3T3 Cell Line. Retrieved 12 March 2021. Kristian Björnstad; Anders Helander; Peter Hultén; ...

... is a sub clonal cell line derived from the original 3T3 Swiss albino cell line of 1962. The 3T3 original cell line was ... "3T3-L1 Cell Line". Retrieved 22 July 2018. Green, Howard; Kehinde, Olaniyi (March 1974). "Sublines of mouse 3T3 cells that ... from a clonal expansion of Swiss 3T3 cells. In 1962, the original 3T3 cell line that it was established by George Todaro and ... Since 3T3-L1 cells are an immortalized cell line and require a hormonal differentiation, there has been much debate on their ...

Effects on the Cytoskeleton in NIH/3T3 Cells". The Journal of Biochemistry. 125 (5): 960-965. doi:10.1093/oxfordjournals.jbchem ... growth factor of the cell such as to induce the formation of mitogen-activated protein interaction and playing a role in cell ...

Expression of the mutant enzyme in NIH 3T3 cells". The Journal of Clinical Investigation. 86 (1): 351-5. doi:10.1172/JCI114708 ... Collins FS, Rossant J, Wurst W (January 2007). "A mouse for all reasons". Cell. 128 (1): 9-13. doi:10.1016/j.cell.2006.12.018. ... doi:10.1016/j.cell.2013.06.022. PMC 3717207. PMID 23870131. "Infection and Immunity Immunophenotyping (3i) Consortium". Tanoue ... July 2013). "Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes". Cell. 154 (2 ...

"Exogenous Sodium Pyruvate Stimulates Adipogenesis of 3T3-L1 Cells". Journal of Cellular Biochemistry. 117 (1): 39-48. doi: ... In the body, one way in which sodium pyruvate provides energy to cells is through pyruvate conversion to acetyl-CoA which then ... It is commonly added to cell culture media as an additional source of energy, but may also have protective effects against ... sodium pyruvate has been used in many experiments involving cell cultures to provide more energy. In adipocytes it was found ...

Cohen BD, Green JM, Foy L, Fell HP (Mar 1996). "HER4-mediated biological and biochemical properties in NIH 3T3 cells. Evidence ... Cell. 127 (1): 185-97. doi:10.1016/j.cell.2006.07.037. PMID 17018285. S2CID 18779079. "Entrez Gene: ERBB4 v-erb-a ... Culouscou JM, Plowman GD, Carlton GW, Green JM, Shoyab M (Sep 1993). "Characterization of a breast cancer cell differentiation ... Carpenter G (Mar 2003). "ErbB-4: mechanism of action and biology". Experimental Cell Research. 284 (1): 66-77. doi:10.1016/ ...

These cells developed into the commonly used cell line NIH 3T3. MEFs treated by mitomycin or gamma rays (such treatment makes ... Finally digest the remains by enzymes to obtain single isolated cells and culture the cells in a tissue culture dishes. MEF ... Cell. 126 (4): 663-676. doi:10.1016/j.cell.2006.07.024. hdl:2433/159777. PMID 16904174. (All articles with dead external links ... "Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines". J. Cell Biol ...

In vitro studies on differentiation have used the pre-committed preadipocyte lineage, such as 3T3-L1 and 3T3-F442A cell line, ... Green H, Kehinde O (28 February 1974). "Sublines of mouse 3T3 cells that accumulate lipid". Cell. 1 (3): 113-116. doi:10.1016/ ... PPARγ is necessary and sufficient to promote fat cell differentiation. PPARγ is required for embryonic stem cells (ES cells) ... "Spontaneous heritable changes leading to increased adipose conversion in 3T3 cells". Cell. 7 (1): 105-13. doi:10.1016/0092-8674 ...

Armelin HA (Sep 1973). "Pituitary extracts and steroid hormones in the control of 3T3 cell growth". Proceedings of the National ... For example: FGF15 and FGF19 (FGF15/19) are produced by intestinal cells but act on FGFR4-expressing liver cells to ... "Localisation of a fibroblast growth factor and its effect alone and with hydrocortisone on 3T3 cell growth". Nature. 249 (453 ... While many FGFs can be secreted by cells to act on distant targets, some FGF act locally within a tissue, and even within a ...

Fusinski, Keith A (2008). Adenovirus 36 E4orf1 gene induces differentiation of 3T3-L1 cells (PhD Dissertation). Wayne State ... Cell. 141 (7): 1135-45. doi:10.1016/j.cell.2010.05.009. PMC 2908380. PMID 20602997. Gavranich, John B; Chang, Anne B (2015). " ... and Merkel cell polyomavirus (MCPyV) in non small cell lung cancer". Experimental and Molecular Pathology. 89 (3): 222-6. doi: ... February 2014). "Coxsackievirus B1 is associated with induction of β-cell autoimmunity that portends type 1 diabetes". Diabetes ...

Moremen KW, Touster O (Jun 1985). "Biosynthesis and modification of Golgi mannosidase II in HeLa and 3T3 cells". The Journal of ... Velasco A, Hendricks L, Moremen KW, Tulsiani DR, Touster O, Farquhar MG (Jul 1993). "Cell type-dependent variations in the ... The Journal of Cell Biology. 115 (6): 1521-34. doi:10.1083/jcb.115.6.1521. PMC 2289207. PMID 1757461. Oka T, Ungar D, Hughson ... Molecular Biology of the Cell. 15 (5): 2423-35. doi:10.1091/mbc.E03-09-0699. PMC 404034. PMID 15004235. "Entrez Gene: MAN2A1 ...

Virtually all eukaryotic cells form such processes upon Rho activation. Fibroblasts such as Swiss 3T3 cells are often used to ... Before the cell can bud, Cdc42 is used to locate the region of the cell's membrane that will begin to bulge into the new cell. ... Before cells can undergo key processes such as budding, mitosis, or locomotion, it must have some manner of cell polarity. One ... Animal cells form many different shapes based on their function and location in the body. Rho proteins help cells regulate ...

explored 3T3-L1 adipocytes cocultured with RAW264.7 cells to examine this potential interaction. RAW264.7 coculture increases ... There was also a GPR84 downregulation in dentritic cell derived from FcRgamma chain KO mice. In microglial cells, the GPR84 ... EST clones corresponding to hgpr84 were from B cells (leukemia), neuroendocrine lung as well as in microglial cells and ... Ly6G + MDSCs in Lal-/- mice show strong immunosuppression on T cells, which contributes to impaired T cell proliferation and ...

"Vitisin a inhibits adipocyte differentiation through cell cycle arrest in 3T3-L1 cells". Biochemical and Biophysical Research ... and NF-κB activation in RAW 264.7 cells". International Immunopharmacology. 9 (3): 319-323. doi:10.1016/j.intimp.2008.12.005. ...

Kolch W, Heidecker G, Lloyd P, Rapp UR (January 1991). "Raf-1 protein kinase is required for growth of induced NIH/3T3 cells". ... Romero F, Martínez-A C, Camonis J, Rebollo A (June 1999). "Aiolos transcription factor controls cell death in T cells by ... cell migration, inhibition of apoptosis, and cell differentiation. Hereditary gain-of-function mutations of c-Raf are ... "X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility". Nat. Cell Biol. 10 (12): 1447-55. doi: ...

"Hindered diffusion of inert tracer particles in the cytoplasm of mouse 3T3 cells". Proc. Natl. Acad. Sci. U.S.A. 84 (14): 4910- ... Examples of these processes include signal transduction from the cell membrane to sites within the cell, such as the cell ... cell signaling, and the generation of action potentials in excitable cells such as endocrine, nerve and muscle cells. The ... without damaging the other cell membranes, only about one quarter of cell protein was released. These cells were also able to ...

"Purified plasma membranes inhibit polypeptide growth factor-induced DNA synthesis in subconfluent 3T3 cells". Journal of Cell ... Cell. 126 (2): 335-348. doi:10.1016/j.cell.2006.05.046. PMC 2851639. PMID 16873064. Carter, Andrew P.; Garbarino, Joan E.; ... He was the president of the American Society for Cell Biology in 2012. He has also been an investigator at the Howard Hughes ... Ronald David Vale ForMemRS (born 1959) is an American biochemist and cell biologist. He is a professor at the Department of ...

"Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells". Genes Dev. 5 (9): 1538-52. doi:10.1101 ... Cell. 8 (4): 817-28. doi:10.1016/S1097-2765(01)00366-5. PMID 11684017. Ho PA, Alonzo TA, Gerbing RB, Pollard J, Stirewalt DL, ... The encoded protein is a key regulator of adipogenesis (the process of forming new fat cells) and the accumulation of lipids in ... Wang H, Iakova P, Wilde M, Welm A, Goode T, Roesler WJ, Timchenko NA (October 2001). "C/EBPalpha arrests cell proliferation ...

"Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells". Genes & Development. 5 (9): 1538-1552 ... Mo X, Kowenz-Leutz E, Xu H, Leutz A (January 2004). "Ras induces mediator complex exchange on C/EBP beta". Molecular Cell. 13 ( ... Davydov IV, Krammer PH, Li-Weber M (December 1995). "Nuclear factor-IL6 activates the human IL-4 promoter in T cells". Journal ... CEBP-beta is critical for normal macrophage functioning, an important immune cell sub-type; mice unable to express CEBP-beta ...

While initial studies revealed that co-culturing epithelial cells with Swiss 3T3 cells J2 was essential for CRC induction, with ... May 2013). "TAP-deficient human iPS cell-derived myeloid cell lines as unlimited cell source for dendritic cell-like antigen- ... June 2014). "Human somatic cell nuclear transfer using adult cells". Cell Stem Cell. 14 (6): 777-80. doi:10.1016/j.stem.2014.03 ... June 2013). "Human embryonic stem cells derived by somatic cell nuclear transfer". Cell. 153 (6): 1228-38. doi:10.1016/j.cell. ...

Cao Z, Umek RM, McKnight SL (Sep 1991). "Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells ... CEBPD is involved in regulation of apoptosis and cell proliferation. It probably acts as tumor suppressor. One study in mice ... Cell Biology. 29 (12): 1525-39. doi:10.1016/S1357-2725(97)00083-6. PMID 9570146. Zhu Y, Saunders MA, Yeh H, Deng WG, Wu KK (Mar ... Cytogenetics and Cell Genetics. 70 (3-4): 188-91. doi:10.1159/000134030. PMID 7789168. Cleutjens CB, van Eekelen CC, van Dekken ...

"Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells". Nature. 313 (5999): 241-3. ... Cyclin D1 is expressed in all adult human tissues with the exception of cells derived from bone marrow stem cell lines (both ... Amplification of the CCND1 gene is present in: non-small cell lung cancers (30-46%) head and neck squamous cell carcinomas (30- ... Chromosomal translocation around the cyclin D1 gene locus is often seen in B mantle cell lymphoma. In mantle cell lymphoma, ...

"Entrez Gene: MDM4 Mdm4, transformed 3T3 cell double minute 4, p53 binding protein (mouse)". Strachan GD, Jordan-Sciutto KL, ... regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development". Mol. Cell. Biol. 22 (15 ... Cell. Biol. 22 (21): 7562-71. doi:10.1128/MCB.22.21.7562-7571.2002. PMC 135668. PMID 12370303. Badciong JC, Haas AL (2003). " ... Sabbatini P, McCormick F (2002). "MDMX inhibits the p300/CBP-mediated acetylation of p53". DNA Cell Biol. 21 (7): 519-25. doi: ...

"Modulation of alpha-actinin levels affects cell motility and confers tumorigenicity on 3T3 cells". J. Cell Sci. 107 (7): 1773- ... "Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin". J. Cell Biol. 130 (1): 67 ... and alpha-actinin-binding protein localized at cell-cell adherens junctions". J. Biol. Chem. 278 (6): 4103-11. doi:10.1074/jbc. ... Cell. 10 (4): 819-32. doi:10.1091/mbc.10.4.819. PMC 25204. PMID 10198040. Vallenius T, Luukko K, Mäkelä TP (April 2000). "CLP- ...

"Bone morphogenetic protein-2 causes commitment and differentiation in C3H10T1/2 and 3T3 cells". Growth Factors. 9 (1): 57-71. ... "Regeneration of Thyroid Function by Transplantation of Differentiated Pluripotent Stem Cells". Cell Stem Cell. 17 (5): 527-42. ... If these cells also receive signals from FGF, they will differentiate into the spinal cord; in the absence of FGF the cells ... Also in conjunction with FGF2 it can produce progenitor thyroid cells from pluripotent stem cells in mice and humans. BMP4 has ...

Cao Z, Umek RM, McKnight SL (Sep 1991). "Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells ... Cell culture studies in mice and human microglia lines also find increased C/EBPβ activity associated with pathogenic ... C/EBPβ plays a role in neuronal differentiation, in learning, in memory processes, in glial and neuronal cell functions, and in ... In contrast, ectopic expression of C/EBPβ and δ in 3T3-L1 preadipocytes promotes adipogenesis, even in the absence of ...

Enhancement of BALB/c 3T3 cells transformation by 1,2- dibromoethane promoting effect. Carcinogenesis 17(2):225-231. Story DL, ... In 1962, a study showed that 2⁄3 of the investigated rats exposed to 9000 ppm TeCA for 29 days had decreased red blood cells ... Workers in an artificial silk factory that had regularly inhaled TeCA, showed elevated white blood cell levels and slight ...

... coated it with 3T3 mouse cells to form connective tissue and topped it up with human bone cells in order to create a stronger ... The 3T3 mouse cells all come from a mouse who lived in the 1970s. The research and development of "Victimless Leather" has been ... To idealize the "victimless" of the jacket, immortalized cell lines or cells that divide and multiply forever once they are ... It is a prototype of a stitch-less jacket, grown from cell cultures into a layer of tissue supported by a coat shaped polymer ...

Ram, P. T.; Horvath, C. M.; Iyengar, R (2000). "Stat3-mediated transformation of NIH-3T3 cells by the constitutively active ... His laboratory focuses on how cell signals are routed and processed through cellular signaling networks within cells to ... "Stat3-mediated transformation of NIH-3T3 cells by the constitutively active Q205L Galphao protein". Science. 287 (5450): 142-4 ... Cell. 133 (4): 666-80. doi:10.1016/j.cell.2008.04.025. PMC 2728678. PMID 18485874. Bhalla, U. S.; Iyengar, R (1999). "Emergent ...