Sphingomyelin phosphodiesterase - Wikipedia
Sphingomyelin phosphodiesterase (EC 3.1.4.12, also known as neutral sphingomyelinase, sphingomyelinase, or SMase; systematic ... "Bacterial toxin closes gate on immune response" 2008-02-13 Sphingomyelin+Phosphodiesterase at the U.S. National Library of ... "Structural basis of the sphingomyelin phosphodiesterase activity in neutral sphingomyelinase from Bacillus cereus". J. Biol. ... SMase is a member of the DNase I superfamily of enzymes and is responsible for breaking sphingomyelin (SM) down into ...
Smpdl3a MGI Mouse Gene Detail - MGI:1931437 - sphingomyelin phosphodiesterase, acid-like 3A
Trivalent chromium induces autophagy by activating sphingomyelin phosphodiesterase 2 and increasing cellular ceramide levels in...
We found that trivalent chromium [Cr(III)] induced autophagy by activating sphingomyelin phosphodiesterase 2 (SMPD2). SMPD2 ... We found that trivalent chromium [Cr(III)] induced autophagy by activating sphingomyelin phosphodiesterase 2 (SMPD2). SMPD2 ... Trivalent chromium induces autophagy by activating sphingomyelin phosphodiesterase 2 and increasing cellular ceramide levels in ... Keywords: ATAD3A; autophagy; ceramide; dihydrodiol dehydrogense; reactive oxygen species; sphingomyelin phosphodiesterase 2. ...
MedlinePlus: Genes: S
Acid sphingomyelinase (SMPD1) Mouse Monoclonal Antibody [Clone ID: OTI3H7] - TA803659 | OriGene
Purified recombinant protein of Homo sapiens sphingomyelin phosphodiesterase 1, acid lysosomal (SMPD1), transcript variant 1, ... Transient overexpression lysate of sphingomyelin phosphodiesterase 1, acid lysosomal (SMPD1), transcript variant ASM-1 ... The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded ...
positive regulation of nitric oxide biosynthetic process - Ontology Report - Rat Genome Database
Beta-galactosidase - wikidoc
Anti-SMPD3 Antibodies | Invitrogen ...
Sphingomyelin phosphodiesterase 3; sphingomyelin phosphodiesterase 3, neutral; sphingomyelin phosphodiesterase 3, neutral ... neutral sphingomyelin phosphodiesterase 3; neutral sphingomyelinase 2; Neutral sphingomyelinase II; NSMASE2; nSMase-2; SMPD3; ... Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, ...
ASM1 (SMPD1) ORF cDNA clone | Expression-ready | InvivoGen
Sequence search - BRENDA Enzyme Database
Expression of Alkaline Sphingomyelinase in Yeast Cells and Anti-inflammatory Effects of the Expressed Enzyme in a Rat Colitis...
Sphingomyelin Phosphodiesterase Medicin och livsvetenskap 100% * Colitis Medicin och livsvetenskap 76% * Yeasts Medicin och ... N2 - Alkaline sphingomyelinase (Alk-SMase) is a key enzyme in the intestinal tract for digestion of dietary sphingomyelin (SM ... AB - Alkaline sphingomyelinase (Alk-SMase) is a key enzyme in the intestinal tract for digestion of dietary sphingomyelin (SM ... Alkaline sphingomyelinase (Alk-SMase) is a key enzyme in the intestinal tract for digestion of dietary sphingomyelin (SM), ...
Sphingomyelinase Deficiency: Practice Essentials, Pathophysiology, Etiology
Analysis of the sphingomyelin phosphodiesterase 1 gene (SMPD1) in Turkish Niemann-Pick disease patients: mutation profile and ... In addition to sphingomyelin, bis(monoacylglycero)phosphate and lyso-sphingomyelin are also elevated. Cholesterol, ... Sphingomyelin is a major component of cell membranes and the principal phospholipid of the myelin sheath. [1, 5] (See the image ... Progressive deposition of sphingomyelin in the central nervous system (CNS) results in the neurodegenerative course observed in ...
Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents | Nature...
10N). However, GBA, beta-hexosaminidase A (HEX-A), sphingomyelin synthase 1 (SGMS-1), and sphingomyelin phosphodiesterase 1 ( ... PCs phosphatidylcholines, PAs phosphatidic acids, SMs sphingomyelins, LPCs lyso-PCs, PIs phosphatidylinositols, PSs ... 3I). Phosphosphingolipids, phosphorylated derivatives of ceramide, including ceramide-1-phosphate (CerP), sphingomyelins (SMs ... and sphingomyelins (SMs). There may also be a decrease of ceramide due to reduced activity of glycolipids pathways. Because of ...
Enzyme families | IUPHAR/BPS Guide to PHARMACOLOGY
Phosphatidyl serine: Uses, Interactions, Mechanism of Action | DrugBank Online
Sphingomyelin phosphodiesterase d activity. Specific Function. Catalyzes the hydrolysis of membrane sphingomyelin to form ... Sphingomyelin phosphodiesterase activity. Specific Function. Catalyzes the hydrolysis of sphingomyelin to form ceramide and ... USphingomyelin phosphodiesterase 3. Not Available. Humans. UProbable phospholipid-transporting ATPase IA. Not Available. Humans ...
Jacqueline Ohanian - Research output - Research Explorer The University of Manchester
Early limited nitrosamine exposures exacerbate high fat diet-mediated type 2 diabetes and neurodegeneration | BMC Endocrine...
... and sphingomyelin phosphodiesterases (SMPD), due to their demonstrated relevance to neurodegeneration [45, 83]. HFD feeding ... sphingomyelin phosphodiesterase 1 (SMPD1), (G) SMPD3, (H) Serine palmitoyltransferase 1 (SPTLC1), and (I) SPTLC2. The mRNA ... Nakane M, Kubota M, Nakagomi T, Tamura A, Hisaki H, Shimasaki H, Ueta N: Lethal forebrain ischemia stimulates sphingomyelin ... Alessenko AV, Bugrova AE, Dudnik LB: Connection of lipid peroxide oxidation with the sphingomyelin pathway in the development ...
A cell-autonomous requirement for neutral sphingomyelinase 2 in bone mineralization | Journal of Cell Biology | Rockefeller...
... which cleaves sphingomyelin to generate bioactive lipids, is required for chondrocyte apoptosis and, cell autonomously, for ... A deletion mutation called fro (fragilitas ossium) in the murine Smpd3 (sphingomyelin phosphodiesterase 3) gene leads to a ... A deletion in the gene encoding sphingomyelin phosphodiesterase 3 (Smpd3) results in osteogenesis and dentinogenesis imperfecta ... A deletion in the gene encoding sphingomyelin phosphodiesterase 3 (Smpd3) results in osteogenesis and dentinogenesis imperfecta ...
Niemann-Pick Diseases | Profiles RNS
FDA Approvals, Highlights, and Summaries: Endocrinology, Diabetes, and Cardiology
GSE7509 FCGRIIB VS TNFA IL1B IL6 PGE STIM DC UP
Showing Compound LysoSM(d18:1) (FDB023932) - FooDB
Evaluation of CEP55, SERPINE1 and SMPD3 genes and proteins as diagnostic and prognostic biomarkers in gastric carcinoma in...
This present study assessed centrosomal protein-55 (CEP55) serpin family E member 1 (SERPINE1) and sphingomyelin ... phosphodiesterase 3 (SMPD3) genes and proteins in gastric adenocarcinoma with different tumor progression features. Thirty ... and sphingomyelin phosphodiesterase 3 (SMPD3) genes and proteins in gastric adenocarcinoma with different tumor progression ... and sphingomyelin phosphodiesterase 3 (SMPD3) genes were identified and included in these signatures. Few studies ...
Erjefält, J.<...
Showing Compound Ceramide (d18:1/18:0) (FDB023537) - FooDB
Sphingomyelin phosphodiesterase. SMPD1. P17405 Ceramide glucosyltransferase. UGCG. Q16739 Phosphatidylinositol N- ... Ceramides (N-acylsphingosine) are one of the hydrolysis byproducts of sphingomyelin by the enzyme sphingomyelinase ( ... sphingomyelin phosphorylcholine phosphohydrolase E.C.3.1.4.12) which has been identified in the subcellular fractions of human ...
Graduate Studies - Scholarly Output - Augusta University Research Profiles
Global Center for Health Security - Research output - Research Nebraska
Kraft, C. S., Kortepeter, M. G., Gordon, B., Sauer, L. M., Shenoy, E. S., Eiras, D. P., Larson, L. A., Garland, J. A., Mehta, A. K., Barrett, K., Price, C. S., Croyle, C., West, L. R., Noren, B., Kline, S., Arguinchona, C., Arguinchona, H., Grein, J. D., Connally, C., McLellan, S., & 8 othersRisi, G. F., Uyeki, T. M., Davey, R. T., Schweinle, J. E., Schwedhelm, M. M., Harvey, M., Hunt, R. C. & Kratochvil, C. J., Jan 1 2019, In: Health Security. 17, 1, p. 35-45 11 p.. Research output: Contribution to journal › Article › peer-review ...
Products Archive - Exalpha Biologicals inc.
SZGR2
sphingomyelin phosphodiesterase 3. 16q22.1. CV:PGCnp. INTRACELLULAR SIGNAL TRANSDUCTION. CompositeSet. Darnell FMRP targets. ... phosphodiesterase 6B. 4p16.3. CV:PGCnp. 57732. ZFYVE28. LST2 , LYST2. zinc finger FYVE-type containing 28. 4p16.3. CV:GWAScat. ... glycerophosphodiester phosphodiesterase domain containing 5. 11q13.4-q13.5. CV:PGCnp. DMG:Wockner_2014. DNM:Fromer_2014. ...