Sphingomyelin phosphodiesterase (EC 3.1.4.12, also known as neutral sphingomyelinase, sphingomyelinase, or SMase; systematic ... "Bacterial toxin closes gate on immune response" 2008-02-13 Sphingomyelin+Phosphodiesterase at the U.S. National Library of ... "Structural basis of the sphingomyelin phosphodiesterase activity in neutral sphingomyelinase from Bacillus cereus". J. Biol. ... SMase is a member of the DNase I superfamily of enzymes and is responsible for breaking sphingomyelin (SM) down into ...
IPR017064 Acid sphingomyelinase-like phosphodiesterase, predicted. IPR004843 Calcineurin-like phosphoesterase domain, ApaH type ...
We found that trivalent chromium [Cr(III)] induced autophagy by activating sphingomyelin phosphodiesterase 2 (SMPD2). SMPD2 ... We found that trivalent chromium [Cr(III)] induced autophagy by activating sphingomyelin phosphodiesterase 2 (SMPD2). SMPD2 ... Trivalent chromium induces autophagy by activating sphingomyelin phosphodiesterase 2 and increasing cellular ceramide levels in ... Keywords: ATAD3A; autophagy; ceramide; dihydrodiol dehydrogense; reactive oxygen species; sphingomyelin phosphodiesterase 2. ...
SMPD1: sphingomyelin phosphodiesterase 1. *SMS: spermine synthase. *SNAI2: snail family transcriptional repressor 2 ...
Purified recombinant protein of Homo sapiens sphingomyelin phosphodiesterase 1, acid lysosomal (SMPD1), transcript variant 1, ... Transient overexpression lysate of sphingomyelin phosphodiesterase 1, acid lysosomal (SMPD1), transcript variant ASM-1 ... The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded ...
sphingomyelin phosphodiesterase 3. IMP. RGD. PMID:14720208. RGD:10042970. NCBI chr19:34,162,337...34,245,786 Ensembl chr19: ...
From sphingomyelin. Sphingomyelin phosphodiesterase Sphingomyelin phosphodiesterase 1. From sulfatide. Arylsulfatase A. ...
Sphingomyelin phosphodiesterase 3; sphingomyelin phosphodiesterase 3, neutral; sphingomyelin phosphodiesterase 3, neutral ... neutral sphingomyelin phosphodiesterase 3; neutral sphingomyelinase 2; Neutral sphingomyelinase II; NSMASE2; nSMase-2; SMPD3; ... Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, ...
Sphingomyelin phosphodiesterase 1. Back to the top Specifications. Human ASM1 (pUNO1-hASM1). ORF size : 1893 bp Subclone : NcoI ...
sphingomyelin phosphodiesterase. Homo sapiens. P17405. 1 transm. helix 631 amino acids. 69936 ...
Sphingomyelin Phosphodiesterase Medicin och livsvetenskap 100% * Colitis Medicin och livsvetenskap 76% * Yeasts Medicin och ... N2 - Alkaline sphingomyelinase (Alk-SMase) is a key enzyme in the intestinal tract for digestion of dietary sphingomyelin (SM ... AB - Alkaline sphingomyelinase (Alk-SMase) is a key enzyme in the intestinal tract for digestion of dietary sphingomyelin (SM ... Alkaline sphingomyelinase (Alk-SMase) is a key enzyme in the intestinal tract for digestion of dietary sphingomyelin (SM), ...
Analysis of the sphingomyelin phosphodiesterase 1 gene (SMPD1) in Turkish Niemann-Pick disease patients: mutation profile and ... In addition to sphingomyelin, bis(monoacylglycero)phosphate and lyso-sphingomyelin are also elevated. Cholesterol, ... Sphingomyelin is a major component of cell membranes and the principal phospholipid of the myelin sheath. [1, 5] (See the image ... Progressive deposition of sphingomyelin in the central nervous system (CNS) results in the neurodegenerative course observed in ...
10N). However, GBA, beta-hexosaminidase A (HEX-A), sphingomyelin synthase 1 (SGMS-1), and sphingomyelin phosphodiesterase 1 ( ... PCs phosphatidylcholines, PAs phosphatidic acids, SMs sphingomyelins, LPCs lyso-PCs, PIs phosphatidylinositols, PSs ... 3I). Phosphosphingolipids, phosphorylated derivatives of ceramide, including ceramide-1-phosphate (CerP), sphingomyelins (SMs ... and sphingomyelins (SMs). There may also be a decrease of ceramide due to reduced activity of glycolipids pathways. Because of ...
Sphingomyelin synthase C. *Sphingomyelin phosphodiesterase C. *Neutral sphingomyelinase coupling factors C. *Ceramide ...
Sphingomyelin phosphodiesterase d activity. Specific Function. Catalyzes the hydrolysis of membrane sphingomyelin to form ... Sphingomyelin phosphodiesterase activity. Specific Function. Catalyzes the hydrolysis of sphingomyelin to form ceramide and ... USphingomyelin phosphodiesterase 3. Not Available. Humans. UProbable phospholipid-transporting ATPase IA. Not Available. Humans ...
Sphingomyelin Phosphodiesterase 100% * Endothelin 1 100% * Vascular Cell Adhesion Molecule 1 100% ...
... and sphingomyelin phosphodiesterases (SMPD), due to their demonstrated relevance to neurodegeneration [45, 83]. HFD feeding ... sphingomyelin phosphodiesterase 1 (SMPD1), (G) SMPD3, (H) Serine palmitoyltransferase 1 (SPTLC1), and (I) SPTLC2. The mRNA ... Nakane M, Kubota M, Nakagomi T, Tamura A, Hisaki H, Shimasaki H, Ueta N: Lethal forebrain ischemia stimulates sphingomyelin ... Alessenko AV, Bugrova AE, Dudnik LB: Connection of lipid peroxide oxidation with the sphingomyelin pathway in the development ...
... which cleaves sphingomyelin to generate bioactive lipids, is required for chondrocyte apoptosis and, cell autonomously, for ... A deletion mutation called fro (fragilitas ossium) in the murine Smpd3 (sphingomyelin phosphodiesterase 3) gene leads to a ... A deletion in the gene encoding sphingomyelin phosphodiesterase 3 (Smpd3) results in osteogenesis and dentinogenesis imperfecta ... A deletion in the gene encoding sphingomyelin phosphodiesterase 3 (Smpd3) results in osteogenesis and dentinogenesis imperfecta ...
SPHINGOMYELIN PHOSPHODIESTERASE) or defects in intracellular transport, resulting in the accumulation of SPHINGOMYELINS and ...
... caused by pathogenic variants in the sphingomyelin phosphodiesterase 1 (SMPD1) gene. ASM degrades sphingomyelin to ceramide and ... ASM deficiency causes intra-lysosomal accumulation of sphingomyelin (and cholesterol and other cell membrane lipids) in various ...
sphingomyelin phosphodiesterase.... SMU1. 55234. SMU1. SMU1 DNA replication regulator .... SNAP47. 116841. SNAP47. synaptosome ...
Sphingomyelin phosphodiesterase. SMPD1. P17405 Non-lysosomal glucosylceramidase. GBA2. Q9HCG7 Proactivator polypeptide. PSAP. ... It is then converted to Sphingomyelin via the enzyme sphingosine N-acyltransferase (EC 2.3.1.24). [HMDB]. ...
This present study assessed centrosomal protein-55 (CEP55) serpin family E member 1 (SERPINE1) and sphingomyelin ... phosphodiesterase 3 (SMPD3) genes and proteins in gastric adenocarcinoma with different tumor progression features. Thirty ... and sphingomyelin phosphodiesterase 3 (SMPD3) genes and proteins in gastric adenocarcinoma with different tumor progression ... and sphingomyelin phosphodiesterase 3 (SMPD3) genes were identified and included in these signatures. Few studies ...
Sphingomyelin Phosphodiesterase 100% * Large Intestine 66% * Homeostasis 54% * Dendritic Cells 49% * T-Lymphocytes 45% ...
Sphingomyelin phosphodiesterase. SMPD1. P17405 Ceramide glucosyltransferase. UGCG. Q16739 Phosphatidylinositol N- ... Ceramides (N-acylsphingosine) are one of the hydrolysis byproducts of sphingomyelin by the enzyme sphingomyelinase ( ... sphingomyelin phosphorylcholine phosphohydrolase E.C.3.1.4.12) which has been identified in the subcellular fractions of human ...
Sphingomyelin Phosphodiesterase 43% 45 Scopus citations * The mechanisms shaping the repertoire of CD4+ Foxp3+ regulatory T ...
Kraft, C. S., Kortepeter, M. G., Gordon, B., Sauer, L. M., Shenoy, E. S., Eiras, D. P., Larson, L. A., Garland, J. A., Mehta, A. K., Barrett, K., Price, C. S., Croyle, C., West, L. R., Noren, B., Kline, S., Arguinchona, C., Arguinchona, H., Grein, J. D., Connally, C., McLellan, S., & 8 othersRisi, G. F., Uyeki, T. M., Davey, R. T., Schweinle, J. E., Schwedhelm, M. M., Harvey, M., Hunt, R. C. & Kratochvil, C. J., Jan 1 2019, In: Health Security. 17, 1, p. 35-45 11 p.. Research output: Contribution to journal › Article › peer-review ...
Sphingomyelin Phosphodiesterase 3. Blocking Peptide. X2288B. LASS2 (Longevity Assurance Homolog 2). Blocking Peptide. ...
sphingomyelin phosphodiesterase 3. 16q22.1. CV:PGCnp. INTRACELLULAR SIGNAL TRANSDUCTION. CompositeSet. Darnell FMRP targets. ... phosphodiesterase 6B. 4p16.3. CV:PGCnp. 57732. ZFYVE28. LST2 , LYST2. zinc finger FYVE-type containing 28. 4p16.3. CV:GWAScat. ... glycerophosphodiester phosphodiesterase domain containing 5. 11q13.4-q13.5. CV:PGCnp. DMG:Wockner_2014. DNM:Fromer_2014. ...