The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases ... Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases ... "Entrez Gene: DUSP4 dual specificity phosphatase 4". Hoek KS, Schlegel NC, Eichhoff OM, Widmer DS, Praetorius C, Einarsson SO, ... Dual specificity protein phosphatase 4 is an enzyme that in humans is encoded by the DUSP4 gene. ...

Dual Specificity Phosphatase 6 / isolation & purification * Genotype * Microscopy / methods* * Multiprotein Complexes / ...

Wu, G. S. Role for DUSP1 (dual-specificity protein phosphatase 1) in the regulation of autophagy. Autophagy 12, 1791-1803. ... 2B). The protein encoded by DUSP1 is a phosphatase that has dual specificity for amino acids such as tyrosine and threonine. ... 2A and 3). Interestingly, only one gene, dual specificity phosphatase 1 (DUSP1), was common for 24H and 48H, but surprisingly, ... Hoppstadter, J. & Ammit, A. J. Role of dual-specificity phosphatase 1 in glucocorticoid-driven anti-inflammatory responses. ...

DUSP9 dual specificity phosphatase 9 [Homo sapiens] DUSP9 dual specificity phosphatase 9 [Homo sapiens]. Gene ID:1852 ... a Dual-Specificity Phosphatase with a Key Role in Cell Biology and Human Diseases. Title: DUSP9, a Dual-Specificity Phosphatase ... dual specificity protein phosphatase 9. Names. map kinase phosphatase 4. mitogen-activated protein kinase phosphatase 4. serine ... DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific ...

HES1-mediated dual specificity phosphatase 1 repression and subsequent ERK activation (79); iv) HES1-mediated phosphatase and ... a dual variable domain immunoglobulin (DVD-Ig) targeting DLL4 and VEGF, demonstrates superior efficacy and favorable safety ... receptor-type tyrosine-protein phosphatase F and TRIO and F-actin-binding protein, which activates RAC1 to maintain vascular ... 6 Ranganathan P, Weaver KL and Capobianco AJ: Notch signalling in solid tumours: A little bit of everything but not all the ...

Glucocorticoid regulation of mouse and human dual specificity phosphatase 1 (DUSP1) genes: unusual cis-acting elements and ... Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases. Oncogene. 2007;26:3203-3213. ... Protein phosphatases and the regulation of mitogen-activated protein kinase signalling. Curr Opin Cell Biol. 2000;12:186-192. ... MAP kinase phosphatase 1: a novel mediator of biological effects of glucocorticoids? J Endocrinol. 2003;178:5-12. ...

Dual-specificity phosphatase 6 genetic variants associated with risk of lung squamous cell carcinoma in Han Chinese.. J Cancer ... and dual-specificity phosphatase 6 (DUSP6) in a hospital-based case and control cohort of individuals for association with risk ... Assessment of topoisomerase II-alpha gene status by dual color chromogenic Indian J Pathol Microbiol. 2017 Oct-Dec; 60(4):475- ... Finally, OTIs directed against the PML-RARA breakpoint displayed cleavage specificity for oligonucleotides with the ...

Category: Dual-Specificity Phosphatase. M. M. Site-directed mutagenesis of and and signifies that the arousal from the ... whereas prephosphorylation from the phosphatase complicated by PKA inhibits the PKC phosphorylation of Spo7. Collectively, this ... nRIM1mt = 6; nwild-type = 9. Download Shape 3-2, DOCX document Figure 3-3. Overview of check- and p-values for amplitude and ...

dual specificity phosphatase 12 [Source:ZFIN;Acc:Z... [more]. dusp6. 8.727e-20. 43.85. dual specificity phosphatase 6 [Source: ... dual specificity phosphatase 7 [Source:NCBI gene;A... [more]. dusp6. 1.920e-19. 43.75. dual specificity phosphatase 6 [Source: ... dual specificity phosphatase 12 [Source:ZFIN;Acc:Z... [more]. dusp12. 1.550e-44. 34.44. dual specificity phosphatase 12 [Source ... dual specificity phosphatase 7 [Source:ZFIN;Acc:ZD... [more]. dusp22b. 5.943e-19. 34.62. dual specificity phosphatase 22b [ ...

Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases ... The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases ... Has a specificity for the ERK family (PubMed:9858808). Plays an important role in alleviating chronic postoperative pain. ... The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases ...

Mitogen-activated protein kinase phosphatase 4, MAP kinase phosphatase 4, MKP4, MKP-4, Dual specificity protein phosphatase ... Applications: Dual specificity protein phosphatase homolog hMKP-R antibody can be used for the detection of Dual specificity ... MKP4, Dual specificity protein phosphatase 9, Mitogen-activated protein kinase phosphatase 4, MAP kinase phosphatase 4, MKP4, ... Dual specificity protein phosphatase 9, Mitogen-activated protein kinase phosphatase 4, MAP kinase phosphatase 4, MKP4, MKP-4, ...

... dual specificity phosphatase 11 (RNA/RNP complex 1-interacting). Synonyms: 2010300F21Rik. Gene Family:. Phosphatase ...

In addition, eHSP70 increased the expression of the GR target dual-specificity phosphatase 1 (DUSP-1). In doing so, eHSP70 ... Extracellular Heat Shock Protein 70 Increases the Glucocorticoid Receptor and Dual-Specificity Phosphatase 1 via Toll-like ... 6. [Dermatophagoides farinae induces conjunctival epithelial cell damage to promote neutrophil migration and neutrophil ... The mRNA expression of IL-1ß, IL-6, IL-8, TNF-α, IL-10, and TGF-ß genes was determined by RT-qPCR from coinfected AGS cells. ...

... wherein the serine protease is at least 2 selected from the group consisting of kallikrein 6 (KLK6), kallikrein 7 (KLK7), and ... dual specificity phosphatase 1), ETS1 (v-ets avian erythroblastosis virus E26 oncogene homolog 1), IGFBP5 (insulin-like growth ... aMG 479 is a monoclonal antibody that is a potent inhibitor of the IGF 1 receptor and OSI-906 is an oral dual kinase inhibitor ... however, it has low specificity as a single marker and is not generally recommended for early detection (Karam AK, Karlan BY. ...

... including a number of distinct phosphatase domains: the PTP (protein tyrosine phosphatase), DSP (dual-specificity phosphatase ... Dual. 3 (6). Nematodes. F59A6.4, T05A7.6, H05L14.1. Dual-domain CK1 kinase subfamily. ... While phosphatome analysis lags behind that of the kinomes, an initial survey of C. elegans phosphatases identified 83 PTPs, ... Phosphatases remove phosphates from kinase substrates, both reversing kinase-based activation, and relieving kinase-mediated ...

Where indicated (lanes 5 and 10), ARP2/3 was further incubated with dual-specificity Antarctic phosphatase. ARP2/3 complex ... Antibody specificity was demonstrated by detection of different targets fused to GST tag in transiently transfected lysates ... The Erbin PDZ domain binds with high affinity and specificity to the carboxyl termini of delta-catenin and ARVCF. ... Autofluorescence (AF) and secondary antibody stain (alpha-mouse) served as controls for specificity. Except for AF image, ...

The tumor suppressor phosphatase and tensin homolog (PTEN) is a pleiotropic enzyme, inhibiting phosphatidyl-inositol-3 kinase ( ... PTEN is a protean protein with a dual-specificity cytosolic lipid and tyrosine phosphatase activity. Both own phosphorylation ... For p53, a dual colour probe for cytoband 17p13.1 (172 kb) and region 17p11.1-q11.1 (also Vysis) was used. For each case, 100 ... For PTEN, a dual colour probe for cytoband 10q23 and region 10p11.1-q11.1 (Vysis LSI PTEN Spectrum-Orange and CEP10 Spectrum- ...

Dual specificity phosphatase 6; Fcgr1: Fc Fragment of IgG, High Affinity Ia, Receptor; Atf7: Activating Transcription Factor 7 ... LysMCre-fur(fl/fl) mice were born under normal Mendelian ratios, and unlike T-cell specific CD4Cre-fur(fl/fl) mice [6], they ... 6. Pesu M, Watford WT, Wei L, Xu L, Fuss I, Strober W, Andersson J, Shevach EM, Quezado M, Bouladoux N. T-cell-expressed ... A. Kaplan Meier survival curve for LysMCre-fur(fl/fl) and WT littermate control mice (n = 8/genotype, 6-8 weeks of age, all ...

dual specificity phosphatase 6 [.... EFHC2. 80258. EFHC2. EF-hand domain containing 2 [Sou.... ...

dual specificity phosphatase 6. SRSF protein kinase 1. Image. Gene Ontology Annotations. Cellular Component. *Nucleoplasm ... adenocarcinoma agar assays downregulated du145 dual experiments interleukin invasion knockdown lncap matrix mediator ... adenocarcinoma agar assays downregulated du145 dual experiments interleukin invasion knockdown lncap matrix mediator ... metastasis numerous overexpression phosphatase pivotal plays proliferation promoted prostate remains soft specificity ...

dual specificity phosphatase 6. 12q21.33. CV:PGCnp. DMG:Jaffe_2016. Expression. PMID:cooccur. ... dual specificity phosphatase 10. 1q41. CV:GWASdb. CV:PGCnp. G2Cdb.humanPSD. G2Cdb.humanPSP. ... dual specificity phosphatase 5. 10q25. CV:PGCnp. DMG:Jaffe_2016. PMID:cooccur. ... paired box 6. 11p13. Association. CV:PGCnp. DMG:Jaffe_2016. DMG:Wockner_2014. GO_Annotation. PMID:cooccur. ...

Dual specificity protein phosphatase 6. GLO1. Lactoylglutathione lyase. GMPR. GMP reductase 1 ... Alkaline phosphatase-conjugated goat anti-mouse antibody (1:5000; Proteintech Group, USA) and goat anti-rabbit antibody (1:5000 ... We defined Annexin V positive, PI negative quadrant as early apoptotic cells, while dual Annexin V and PI positive quadrant as ... we conducted flow cytometry analysis using Annexin V-FITC/PI dual staining to figure out whether andrographolide have effect on ...

Dual Specificity Phosphatase 1 24% * Fibrosis 24% * Cytokines 24% * Macrophage Activation 24% ...

Dual specificity protein phosphatase 4 (DUSP4) is a critical negative regulator of the mitogen-activated protein kinase (MAPK) ... Dual-specificity phosphatase-4 (DUSP4) is a tumor suppressor gene that is frequently downregulated in human cancer through both ... Dual specificity protein phosphatase 4 (DUSP4) is a critical negative regulator of the mitogen-activated protein kinase (MAPK) ... Dual specificity phosphatase 4 gene expression in association with triple-negative breast cancer outcome. Breast Cancer Res ...

... and 1,844 significantly differentially expressed annotated genes in acutely infected proliferative Huh 7.5 cells at 6, 48, and ... Dual specificity phosphatase 8. 5.05. 87.30. ENSG00000130766. SESN2. Sestrin 2. 4.84. 593.42. ... Protein phosphatase 2, regulatory subunit B (PR 52). −2.65. −26.85. 72 h. ... Solute carrier family 6 (neurotransmitter transporter, glycine), member 9. 3.65. 153.70. ENSG00000166173. LARP6. La ...

Crystal Structure of the Vaccinia Virus Dual-Specificity Phosphatase VH1. 2wgp. Crystal structure of human dual specificity ... Crystal structure of Dual specificity protein phosphatase 13 (DUSP13). 2q05. Crystal structure of tyr/ser protein phosphatase ... Structure of human dual-specificity phosphatase 27. 3cm3. High Resolution Crystal Structure of the Vaccinia Virus Dual- ... Dual specificity phosphatases (DUSPs) are members of the superfamily of protein tyrosine phosphatases [ (PUBMED:17057753) ( ...

Proximity ligation assay, immunoblotting, and phosphatase assay were performed to study the effect of DUSP3 on the TJ protein ... Dual specificity phosphatase 3 (DUSP3), a suppressor of multiple protein tyrosine (Tyr) kinases, is decreased in lung cancer ... Dual specificity phosphatase 3 (DUSP3), a suppressor of multiple protein tyrosine (Tyr) kinases, is decreased in lung cancer ... Dual-specificity protein tyrosine phosphatase VHR down-regulates c-Jun N-terminal kinase (JNK). Oncogene. 2002;21:2573-83. ...

The dual-specificity phosphatase inhibitor BCI is known to act immediately on Fgf signaling leading to an eventual reduction of ... Embryos were treated with BCI (Dual Specificity Protein Phosphatase 1/6 Inhibitor, Calbiochem) as described (Akiyama et al., ... 6E,F; for individual data, see Fig. S12). We noted that the periodicity was not always precisely four (Fig. 6F), possibly owing ... 6M, we explicitly model the case in which somite sizes scale with PSM size (including the 4-cycle delay) and find that it ...

... explored 36 mRNA-seq libraries in order to study transcriptome dynamics during proliferation and differentiation processes at 6 ... Dual Specificity MAP Kinase Phosphatase 10 (DUSP10) or Protein Tyrosine Phosphatase, Non-Receptor Type 5 (PTPN5) which act as ... kinase p38alpha by the dual specificity phosphatase 16 MAP kinase binding domain in solution. J Biol Chem. 2013;288(39):28347- ... We observed that the expression of Protein Tyrosine Phosphatase Non-Receptor Type 12 (PTPN12), an important phosphatase which ...