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  • Diabetic Neuropathy
  • HealthDay News) - Sudomotor denervation has been demonstrated in individuals with diabetic neuropathy, and the sweat gland innervation index (SGII) correlates with glycated hemoglobin (HbA1c) levels, according to research published online Feb. 1 in Diabetes Care . (empr.com)
  • cohort
  • There were no major adverse events at 6 months in the overall study population, but more specifically, in the renal denervation cohort, there were no major clinical events, including no new renal artery stenosis or worsening renal function and no major bleeding or vascular complications, Kandzari reported. (healio.com)
  • Medtronic's
  • We look forward to moving forward with our clinical evaluation of this next-generation system that aims to augment our portfolio by offering more sophisticated features that should benefit both physicians and patients,' Medtronic's president of coronary & renal denervation Sean Salmon said in prepared remarks. (mdtmag.com)
  • reduces
  • There is ample data that renal denervation reduces blood pressure in animal models and in smaller human trials, and there are at least 30 different methods being tested to denervate the renal arteries. (medpagetoday.com)
  • ablation
  • Ablation Points of Renal Sympathetic Denervation: The More, the Better? (ahajournals.org)
  • Methods and apparatus are provided for selective denervation of conduction pathways in the heart for the treatment of dysrhythmias, including one or more ablation or electroporation catheters having electrodes for stimulating, targeting, and ablating fat pad tissue and other cardiac tissue to selectively. (google.es)
  • Interventional
  • Our pilot study data indicate interventional treatment with renal denervation decreases blood pressure, and most important, slows or even halts the decline of renal function in treatment-resistant patients with chronic kidney disease," Schmieder said in a statement. (empr.com)
  • Treatment
  • The DERENEDIAB study is a proof-of-concept, multi-center, prospective, open, randomized, controlled study of the effectiveness of renal denervation in addition to standardized medical treatment compared to medical treatment alone in diabetic subjects with diabetic nephropathy and resistant proteinuria. (clinicaltrials.gov)
  • systolic
  • The use of a sound methodology, including randomisation and blinded endpoint assessment was enough to see the typical 25-30 mmHg systolic blood pressure decrease observed after renal denervation melt down to less than 3 mmHg, the rest being likely explained by Hawthorne and placebo effects, attenuation of white coat effect, regression to the mean and other physician and patient-related biases. (springer.com)
  • reductions
  • In recent years, concerns have been raised that the magnitude of the blood pressure reductions seen in renal denervation studies without control groups would not hold up in controlled trials, and those concerns now appear to be well founded. (medpagetoday.com)
  • The SPYRAL HTN-ON MED and RADIANCE-HTN SOLO trials tested two different devices in two different patient populations, but results from both studies linked renal denervation with significant reductions in BP on several assessments with little to no safety concerns. (healio.com)
  • conclude
  • Aronow, however, said that it is premature to conclude whether any other renal denervation systems would have fared better in the trial, which "set the bar high. (medpagetoday.com)
  • We conclude that cortical cholinergic denervation in PD and parkinsonian dementia is associated with decreased performance on tests of attentional and executive functioning. (springer.com)
  • blood
  • In our case, we present a 39-year-old patient with high blood pressure (BP) of 10-year evolution, left ventricular hypertrophy, and left putaminal hypertensive intracranial hemorrhage, which occurred one year before denervation. (ahajournals.org)
  • Still, renal denervation is supported by a strong rationale and is occasionally followed by major blood pressure responses in at-risk patients who may otherwise have remained uncontrolled. (springer.com)
  • effect
  • Together, [the SPYRAL HTN-ON MED and OFF MED and RADIANCE-HTN SOLO] trials suggest that a renal denervation class effect might apply, in that performing renal denervation with different intravascular techniques yields the same results. (healio.com)