• Thyroxine-binding globulin (TBG) deficiency is a benign condition that is either acquired or inherited. (medscape.com)
  • 95%) of THs are thyroxine-binding globulin (TBG), transthyretin (TTR, or prealbumin), and albumin. (medscape.com)
  • Thyroxine-binding globulin (TBG) is a 395-amino acid, 54kd polypeptide that is synthesized in the liver and encoded by a single gene copy. (medscape.com)
  • ARUP's Laboratory Test Directory: Thyroxine Binding Globulin. (medscape.com)
  • The thyroid hormones (THs)-thyroxine (T4) and 3,5,3'-triiodothyronine (T3)-circulate in blood by reversibly binding to carrier proteins. (medscape.com)
  • Thyroid-binding globulin (TBG) is produced in the liver and is a circulating protein that reversibly binds thyroid hormones3,5,3'-triiodothyronine (T3) and thyroxine (T4) and carries them in the bloodstream. (medscape.com)
  • In drug discovery, it is of utmost importance to accurately calculate the free energies of binding ligands to various protein targets, such as enzymes and receptors. (lu.se)
  • We combine NMR relaxation experiments with molecular dynamics (MD) simulations to derive a highly detailed picture of how the conformational entropy changes when the protein binds different ligands. (lu.se)
  • Additionally, we compared how MD and grand-canonical Monte Carlo (GCMC) can be used to assess dynamics and thermodynamics of protein-ligand binding for both buried and solvent-exposed binding sites. (lu.se)
  • We would like to understand the 'driving forces' of protein-ligand binding, which amounts to understanding the statistical thermodynamics of the binding process at atomic resolution. (lu.se)
  • Corticosteroid-binding globulin deficiency is a condition with subtle signs and symptoms, the most frequent being extreme tiredness (fatigue), especially after physical exertion. (medlineplus.gov)
  • Some people with corticosteroid-binding globulin deficiency also have a condition called myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). (medlineplus.gov)
  • The prevalence of corticosteroid-binding globulin deficiency is unknown, but it is thought to be a rare disorder. (medlineplus.gov)
  • However, because some people with the disorder have mild or no symptoms, it is likely that corticosteroid-binding globulin deficiency is underdiagnosed. (medlineplus.gov)
  • Mutations in the SERPINA6 gene cause corticosteroid-binding globulin deficiency. (medlineplus.gov)
  • With less functional CBG to bind cortisol, people with corticosteroid-binding globulin deficiency usually have increased unbound cortisol levels. (medlineplus.gov)
  • It is unclear how a decrease in CBG protein and total cortisol leads to the signs and symptoms of corticosteroid-binding globulin deficiency. (medlineplus.gov)
  • We develop a New Keynesian model in which the zero lower bound (ZLB) on nominal interest rates is imposed as an occasionally binding constraint and use this model to examine the duration of ZLB episodes. (repec.org)
  • Durations at the Zero Lower Bound ," Working Papers 2017_05, Business School - Economics, University of Glasgow. (repec.org)
  • Durations at the zero lower bound ," CAMA Working Papers 2017-25, Centre for Applied Macroeconomic Analysis, Crawford School of Public Policy, The Australian National University. (repec.org)
  • Durations at the Zero Lower Bound ," IMES Discussion Paper Series 16-E-11, Institute for Monetary and Economic Studies, Bank of Japan. (repec.org)
  • Negative nominal interest rates: Three ways to overcome the zero lower bound ," The North American Journal of Economics and Finance , Elsevier, vol. 20(3), pages 213-238, December. (repec.org)
  • Negative Nominal Interest Rates: Three ways to overcome the zero lower bound ," CEPR Discussion Papers 7346, C.E.P.R. Discussion Papers. (repec.org)
  • Negative nominal interest rates: three ways to overcome the zero lower bound ," LSE Research Online Documents on Economics 29297, London School of Economics and Political Science, LSE Library. (repec.org)
  • Negative Nominal Interest Rates: Three ways to overcome the zero lower bound ," FMG Discussion Papers dp636, Financial Markets Group. (repec.org)
  • Negative Nominal Interest Rates: Three ways to overcome the zero lower bound ," NBER Working Papers 15118, National Bureau of Economic Research, Inc. (repec.org)
  • We study the transmission of changes in the believed location of the lower bound to longterm interest rates since the introduction of negative interest rate policies. (imf.org)
  • The expectations hypothesis of the term structure combined with a lower bound on policy rates suggests that normal policy transmission is reduced when policy rates approach this lower bound. (imf.org)
  • We show that if market participants revise downward the believed location of the lower bound, this may in itself reduce long-term yields. (imf.org)
  • TIBC was calculated indirectly using the unsaturated iron binding capacity (UIBC) method. (cdc.gov)
  • The unsaturated iron-binding capacity (UIBC) is measured using radioactive iron or spectrophotometric approaches. (medscape.com)
  • The sum of the UIBC and the plasma iron is the total iron-binding capacity (TIBC). (medscape.com)
  • TIBC must not be confused with unsaturated binding capacity (UIBC), which represents the residual after subtraction of serum iron from TIBC. (medscape.com)
  • Therefore, to find the upper bound for the LHS expression, set each variable to its upper bound. (utexas.edu)
  • This upper bound is the same as the RHS, and the comparison is non-strict, so the conclusion holds. (utexas.edu)
  • The guidance provides short-term goals that include both a target mean concentration and an upper bound concentration of sodium for various specified categories of food. (who.int)
  • The upper bound concentration is our goal for the highest sodium concentration for any product in that food category. (who.int)
  • Here we show that RF2 is in an open conformation when bound to the ribosome, allowing GGQ to reach the PTC while still allowing SPF-stop-codon interaction. (nature.com)
  • The well ordered conformation of the helix-helix connector indicates a defined interaction with lipidic surfaces, suggesting that, when bound to larger diameter synaptic vesicles, it can act as a switch between this structure and a previously proposed uninterrupted helix. (rcsb.org)
  • NTG-context] \setuparranging values for perfect bound A5 on A3? (mail-archive.com)
  • The computed hint rewrite-bounds can run this sort of proof: it replaces subterms within comparisons with user-provided upper or lower bounds, depending on the context in which they occur. (utexas.edu)
  • Very rarely, and in the context of anti-TH antibodies in autoimmune thyroid disease, immunoglobulins also may bind TH. (medscape.com)
  • The bounds for each such literal are determined by an abstract interpretation of the term, which recursively finds upper and lower bounds. (utexas.edu)
  • In cases of high TBG, more thyroid hormone will be bound, decreasing free hormone in the blood. (medscape.com)
  • US-bound refugees at participating sites are offered 1-3 doses in each vaccine series, depending on age, availability of appropriate vaccines, time to departure, and logistics. (cdc.gov)
  • The SERPINA6 gene provides instructions for making a protein called corticosteroid-binding globulin (CBG), which is primarily produced in the liver. (medlineplus.gov)
  • A known ferrous iron standard of 105 μmol/L (586 μg/dL) was incubated with serum at a pH of 7.9, which saturates the available binding sites on serum transferrin. (cdc.gov)
  • The index of transferrin present in circulating blood is the iron-binding capacity. (medscape.com)
  • The measurement of the blood's capacity to bind iron with transferrin is the iron-binding capacity. (medscape.com)
  • Total iron-binding capacity (TIBC) is an indirect method assessment of transferrin levels. (medscape.com)
  • The relationship of TIBC and transferrin is disrupted in individuals with conditions that affect transferrin-binding capacity or other iron-binding proteins. (medscape.com)
  • A call mnesia:match_object({kv, 42, '_'}) has a pattern where the key position is bound to an actual value (42) but the value position is unbound ('_' is the wildcard which matches anything). (erlang.org)
  • On the other hand, a call mnesia:match_object({kv, '_', foo}) has a pattern where the key position is unbound but the value position is bound to the value foo. (erlang.org)
  • The amount of total cortisol in the body consists of both bound (inactive) and unbound (active) cortisol. (medlineplus.gov)
  • Title : Accounting for the influence of inflammation on retinol-binding protein in a population survey of Liberian preschool-age children Personal Author(s) : Larson, Leila Margaret;Addo, O. Yaw;Sandalinas, Fanny;Faigao, Katherine;Kupka, Roland;Flores-Ayala, Rafael;Suchdev, Parminder S. (cdc.gov)
  • BIND also enables you to redirect the created DBRM file to an alternative directory. (microfocus.com)
  • In the ideal scenario, we would be able to attribute the contributions from individual molecular groups to the enthalpy and entropy of binding. (lu.se)
  • For these reasons, we are interested in the role of the conformational entropy of the target protein in ligand-binding processes. (lu.se)
  • By comparing NMR-derived order parameters between the free and ligand-bound protein, we estimate the contributions from conformational entropy to the free energy of ligand binding. (lu.se)
  • In addition to NMR relaxation methods, we use isothermal titration calorimetry to obtain the thermodynamic fingerprint of ligand binding, including the total (standard) free energy, enthalpy, and entropy of the process. (lu.se)
  • In addition, when the node with binding SIDs fails, the procedure on each of the related node is illustrated in different cases for two different time periods. (ietf.org)
  • Tanya Has been bound by poverty, toxic relationships, homelessness, daddy issues and generational cycles that kept her in an identity crisis. (apple.com)
  • According to the nonprofit Homeward Bound WNC, close to half of those experiencing homelessness in Buncombe County are veterans, a figure that also includes people benefiting from long-term transitional housing programs. (mountainx.com)
  • A minor proportion of the THs is bound on serum lipoproteins. (medscape.com)
  • We used the paradigmatic GATA-PU.1 axis to explore, at the systems level, dynamic relationships between transcription factor (TF) binding and global gene expression programs as multipotent cells differentiate. (lu.se)
  • and (4) how dynamic modeling of DNA-binding and gene expression data can be used to infer regulatory logic of TF circuitry. (lu.se)
  • The CBG protein attaches (binds) to a hormone called cortisol . (medlineplus.gov)
  • When cortisol is bound to CBG, the hormone is turned off (inactive). (medlineplus.gov)
  • Objective It is recognized that total testosterone (TT) does not sufficiently describe androgen status when sex hormone-binding globulin (SHBG) is altered. (medscape.com)
  • [ 1-6 ] However, they all report that TT could provide misleading information in conditions known to alter sex hormone-binding globulin (SHBG) levels. (medscape.com)
  • In particular, replacing a by its bound here would result in a trivially true hypothesis. (utexas.edu)
  • ISRO's Aditya L1 solar mission successfully completes third earth-bound manoeuvre on its journey to the Sun. (hindustantimes.com)
  • The Indian Space Research Organisation (ISRO) on Sunday informed Aditya L1, India's first solar mission, has successfully performed third earth-bound manoeuvre during its journey to the Sun. (hindustantimes.com)
  • The third Earth-bound maneuvre (EBN#3) is performed successfully from ISTRAC, Bengaluru," the space agency posted on X. (hindustantimes.com)
  • In your script, you need to bind process variables to attach your script variables to the orchestration process' variables. (ibm.com)
  • You should place the Bind Process Variables command before any changes to the script variables you want to bind to the orchestration process' variables. (ibm.com)
  • By default, using the database specified by the DB compiler directive option, the DB2 ECM preprocessor automatically binds your program during the compilation process, creating and storing in your DB2 database a DB2 package required for successful execution. (microfocus.com)
  • How can being house-bound set us free? (artsadmin.co.uk)
  • Furthermore, it is important and challenging to accurately model the large entropic contribution to ligand-binding free energies. (lu.se)
  • If you want to use BIND or BINDDIR when compiling from your Visual COBOL , set one or both of these directives in your project properties on the SQL Preprocessor page. (microfocus.com)
  • We identify anticipation effects that make the ZLB more likely to bind and we show that allowing negative nominal interest rates shortens average durations, but only by about one quarter. (repec.org)
  • Optimal Monetary Policy under Commitment with a Zero Bound on Nominal Interest Rates ," Journal of Money, Credit and Banking , Blackwell Publishing, vol. 38(7), pages 1877-1905, October. (repec.org)
  • Optimal Monetary Policy Under Commitment with a Zero Bound on Nominal Interest Rates ," CEPR Discussion Papers 4111, C.E.P.R. Discussion Papers. (repec.org)
  • Optimal Monetary Policy under Commitment with a Zero Bound on Nominal Interest Rates ," Computing in Economics and Finance 2004 67, Society for Computational Economics. (repec.org)
  • Optimal monetary policy under commitment with a zero bound on nominal interest rates ," Working Paper Series 377, European Central Bank. (repec.org)
  • Optimal monetary policy under commitment with a zero bound on nominal interest rates ," CFS Working Paper Series 2004/13, Center for Financial Studies (CFS). (repec.org)
  • Optimal monetary policy under commitment with a zero bound on nominal interest rates ," Research Working Paper RWP 05-07, Federal Reserve Bank of Kansas City. (repec.org)
  • Optimal monetary policy when interest rates are bounded at zero ," Journal of Economic Dynamics and Control , Elsevier, vol. 29(1-2), pages 97-133, January. (repec.org)
  • Optimal Monetary Policy When Interest Rates are Bound at Zero ," Working Papers 01-12, Ohio State University, Department of Economics. (repec.org)
  • Optimal Monetary Policy When Interest Rates are Bounded at Zero ," Computing in Economics and Finance 2002 8, Society for Computational Economics. (repec.org)
  • For other terms, bounds may be found by user suggestions (verified using backchaining), linear rules, and type reasoning. (utexas.edu)
  • Our recent efforts have focused on aromatic side chains, which often are found in binding sites. (lu.se)
  • This Note investigates the recognition of instances of bound variables and shows how existing mechanisms for dealing with semantics can be used to make such identifications explicit without depending on the direct comparison of the presentational markup. (w3.org)
  • Seit-Nebi, A., Frolova, L., Justesen, J. & Kisselev, L. Class-1 translation termination factors: invariant GGQ minidomain is essential for release activity and ribosomal binding but not for stop codon recognition. (nature.com)
  • Preference is given to Upward Bound Program graduates attending NMC within two years of high school graduation. (fastweb.com)
  • Upward Bound Math and Science (UBMS) is a federal grant program funded by the US Department of Education. (murraystate.edu)
  • Thank you for applying to the PCC Transfer Bound Program! (pasadena.edu)
  • Upon completion of this application, you will be contacted by a Transfer Bound member to schedule a meeting to go over program details and activities. (pasadena.edu)
  • When compiling a program with the ACCESS compiler directive option (default), the DBRM is bound into the connected database, where it creates the SQL package required for execution. (microfocus.com)
  • However, most new arrivals receive some age-appropriate vaccinations through the overseas Vaccination Program for US-Bound Refugees . (cdc.gov)
  • James G. Hooton "Dirichlet semigroup on bounded domains," Rocky Mountain Journal of Mathematics, Rocky Mountain J. Math. (projecteuclid.org)
  • The iron-binding capacity reference range is 255-450 μg/dL. (medscape.com)
  • [ 1 ] Direct measurement of total iron-binding capacity may also be performed. (medscape.com)
  • Here, the structure and dynamics of micelle-bound aS are reported. (rcsb.org)
  • commands are confined to the target elements within the bound instance associated with the SDC file. (intel.com)
  • arguments together disable scoping, treating an entity-bound SDC as a global SDC file. (intel.com)
  • In addition to instructing the DB2 ECM to create a DBRM file, you can also use BIND to specify an alternative filename for the DBRM file. (microfocus.com)
  • Since this is the case, there cannot be any binding to a PL/SQL array because at least one field in the table must be either a VARRAY, NESTED TABLE or ASSOCIATIVE ARRAY data type. (php.net)
  • In one of two complementary studies, IARC scientists analysed data from almost 230 000 women using Mendelian randomization to examine genetic variants known to be associated with circulating concentrations of IGF-1 and insulin-like growth factor-binding protein-3 (IGFBP-3), which may modulate the availability of IGF-1. (who.int)
  • For a term that is an application of a supported arithmetic operator, we first find upper and lower bounds for each argument and then use those bounds to determine the bounds for that operator application. (utexas.edu)
  • This Note examines the treatment of bound variables in Content MathML. (w3.org)
  • This Note provides a self-contained explanation of bound variables in Content MathML. (w3.org)
  • Another Binding SID of B1, named BSID2-B1, is associated with SID-list 3 {SID-B1-Q1, SID-Q3, SID-C}. Note: BSID2-B1 is different from BSID-B1. (ietf.org)
  • Note that it looks like you can't bind a multi-dimensional array with this method. (php.net)
  • These unusually rich dynamics may serve to mitigate the effect of aS binding on membrane fluidity. (rcsb.org)
  • When compiling with NOACCESS, no binding takes place. (microfocus.com)
  • command to bind those variables. (ibm.com)
  • For instance, you might want to create DBRMs ( .bnd files) during compilation, and bind the DBRMs later using the DB2 LUW BIND command against your DB2 LUW databases. (microfocus.com)
  • If not specified or equals to -1, oci_bind_array_by_name() will find the longest element in the incoming array and will use it as the maximum length. (php.net)
  • java.lang.ArrayIndexOutOfBoundsException: Index 1 out of bounds for length 1 at net.sf.basedb.varsearch.vcf.VcfParser$VcfLine.parseFormat(VcfParser.java:297) at net.sf.basedb.varsearch.vcf.VcfParser$VcfLine. (lu.se)
  • Default mode applied to entity-bound SDC files defined in the Intel® Quartus® Prime Pro Edition GUI. (intel.com)
  • Bound variables are central representational primitives in mathematical languages. (w3.org)
  • The first edition of the MathML 2.0 Recommendation [MathML2] was somewhat vague about the identity conditions on bound variables, and as a consequence Content MathML applications were left to guess the exact meaning. (w3.org)
  • The first edition of the MathML 2.0 Recommendation [MathML2] was vague about the identity conditions on bound variables. (w3.org)
  • This is the approach that has been used to clarify the notion of identity of bound variables in the second edition of the MathML 2.0 Recommendation [MathML22e] . (w3.org)