Nitroglycerin. Medical search. Frequent questions

Nitroglycerin ointment or skin patch is used to prevent angina (chest pain) caused by coronary artery disease. (mayoclinic.org)
A less commonly known fact is that in addition to treating angina, nitroglycerin is also used in an ointment to treat the pain that accompanies anal fissures. (pharmaoffer.com)
The rectal ointment form of nitroglycerin was approved by the FDA in 1955. (pharmaoffer.com)
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She takes 35 medications and treatments, including weekly immunosuppressant injections, a nitroglycerin ointment, and a compression device to improve blood circulation in her legs. (medlineplus.gov)

Nitroglycerin belongs to the group of medicines called nitrates. (mayoclinic.org)
Nitrostat (nitroglycerin) Sublingual Tablets are nitrates used to treat or prevent attacks of chest pain ( angina ). (rxlist.com)
These medicines include nitrates (including nitroglycerin), beta-blockers, and calcium channel blockers. (cloudapp.net)
In contrast, Nitroglycerin belongs to the category of medicines known as Nitrates. (fordailymedicine.com)

Nitroglycerin has been used for over 130 years in medicine as a potent vasodilator (causing dilation of the vascular system) to treat heart conditions, such as angina pectoris and chronic heart failure. (wikipedia.org)
The goal of these studies was to demonstrate the protective effect of sildenafil and vardenafil on reperfusion injury and to compare it with the antianginal vasodilator nitroglycerin (NTG). (nih.gov)
Background: Nitroglycerin (also known as glyceryl trinitrate (GTN)), a vasodilator best known for treatment of ischemic heart disease, has also been investigated for its potential therapeutic benefit in ischemic stroke. (nottingham.ac.uk)
Nitroglycerin is a vasodilator. (cloudapp.net)
This was because nitroglycerin is a vasodilator - it dilates (opens) the blood vessels. (yahoo.com)
Nitroglycerin is a vasodilator drug used for the treatment of chest pain and high blood pressure It was first approved in 2000 and is currently marketed by Pfizer, and other companies, depending on the dosage form Nitroglycerin is available in various forms, including a spray form, sublingual tablet form, intravenous form, extended-release tablet form, and transdermal form. (pharmaoffer.com)

Nitroglycerin sublingual tablets are used to treat episodes of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). (medlineplus.gov)
Do not chew, crush, or swallow nitroglycerin sublingual tablets. (medlineplus.gov)
or any of the ingredients in nitroglycerin sublingual tablets. (medlineplus.gov)

These experiments suggest that under conditions of acute partial coronary occlusion, the autoregulatory response results in more fully dilated subendocardial vessels causing them to be less responsive to nitroglycerin. (jci.org)
The lower activity enzyme would leave such patients less responsive to nitroglycerin therapy, Stamler said. (dukehealth.org)

However, elderly patients are more likely to have low blood pressure and age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving nitroglycerin transdermal. (mayoclinic.org)

Following the discovery that amyl nitrite helped alleviate chest pain, the physician William Murrell experimented with the use of nitroglycerin to alleviate angina pectoris and to reduce the blood pressure. (wikipedia.org)
London physician William Murrell experimented with nitroglycerin on himself and tried it on his angina patients. (yahoo.com)

glyceryl trinitrate IV, IV Nitroglycerin, more. (medscape.com)

Are you wondering if it's safe to mix sildenafil (Viagra) with nitroglycerin? (nrpb.org)
Note that both nitroglycerin and sildenafil affect the muscles that control the size of the blood vessels ( 3 ). (nrpb.org)
nitroglycerin IV, sildenafil. (medscape.com)

In April 1866, several crates of nitroglycerin were shipped to California, three of which were destined for the Central Pacific Railroad, which planned to experiment with it as a blasting explosive to expedite the construction of the 1,659-foot-long (506 m) Summit Tunnel through the Sierra Nevada Mountains. (wikipedia.org)
On April 3, 1866, 70 crates of nitroglycerin exploded onboard the California-bound steamship European in Aspinwall, Panama, killing 50 people. (lindahall.org)

Appropriate studies have not been performed on the relationship of age to the effects of nitroglycerin transdermal in the pediatric population. (mayoclinic.org)
bromocriptine decreases effects of nitroglycerin IV by pharmacodynamic antagonism. (medscape.com)
ergotamine decreases effects of nitroglycerin IV by pharmacodynamic antagonism. (medscape.com)

Take nitroglycerin exactly as directed. (medlineplus.gov)
Your doctor may tell you not to take nitroglycerin if you are taking one of these medications. (medlineplus.gov)
To prevent angina, take nitroglycerin before an activity that causes angina. (cloudapp.net)

This led to a complete ban on the transportation of liquid nitroglycerin in California. (wikipedia.org)
Liquid nitroglycerin was widely banned elsewhere, as well, and these legal restrictions led to Alfred Nobel and his company's developing dynamite in 1867. (wikipedia.org)
Following the San Francisco explosion, the California legislature banned the transport of liquid nitroglycerin, forcing Central Pacific workers to exclusively use black powder as their only blasting agent. (lindahall.org)

Distribution of myocardial blood flow during peak coronary flow after intracoronary administration of nitroglycerin or during a decrease in aortic pressure after intravenous nitroglycerin administration was determined by the tissue uptake of an intracoronary bolus of rubidium- 80 . (jci.org)

The administration of sublingual nitroglycerin dilates the coronary arteries and increases side branch visualization. (medscape.com)
Nitroglycerin directly dilates the blood vessels, while Viagra's dilation of the blood vessels is a result of its actions. (fordailymedicine.com)

Nitro-Dur (Nitroglycerin Transdermal) is a transdermal patch used to prevent angina pectoris, a type of chest pain caused by coronary artery disease. (canadadrugsdirect.com)

Minitran, also called nitroglycerin transdermal patch, must be used as determined by the doctor. (canadianpharmacyonline.com)

nitroglycerin IV, vardenafil. (medscape.com)

Talk to your doctor about how to use nitroglycerin tablets to treat angina attacks. (medlineplus.gov)
While heart patients have long appreciated the pain relief brought by nitroglycerin tablets, researchers have just as long puzzled over how the drug works. (duke.edu)

Nitroglycerin is in a class of medications called vasodilators. (medlineplus.gov)
Note that there are more than 201 drugs and other medications that can interact with nitroglycerin ( 7 ). (nrpb.org)
Nitroglycerin 🧪, commonly used in treating chest pain caused by coronary artery disease, can interact with several medications. (likesage.com)
So, this article will explore what Viagra and Nitroglycerin are and the risks of combining these medications. (fordailymedicine.com)

Your doctor will probably tell you to sit down and take one dose of nitroglycerin when an attack begins. (medlineplus.gov)
6-5-HD administered as two bolus injections and 7-Nitroglycerin (NTG, total dose: 2 microg kg(-1) min(-1)) administered as in group 2. (nih.gov)
If you miss a dose of Nitroglycerin Patch, use it as soon as possible. (pharm-europe.com)
In normal mice, treatment with nitroglycerin led to a drop in blood pressure, which increased with drug dose, the researchers showed. (dukehealth.org)
If you miss a dose of Nitroglycerin and you are taking it regularly, take it as soon as possible. (novalarpharm.com)
To relieve angina, take one dose of nitroglycerin as soon as you feel symptoms. (cloudapp.net)
Do not open your sublingual nitroglycerin until you need a dose. (cloudapp.net)

You should not receive this medicine if you had an allergic reaction to nitroglycerin, or if you have certain heart conditions. (stlukes-stl.com)
Do not use Nitroglycerin if you are allergic to any of the components of the medication, if you have allergy to adhesive, you have increased pressure in or severe injury to the head, you have severe anemia, you are taking aphosphodiesterase type 5 inhibitor. (pharm-europe.com)
[ 5 ] Nitroglycerin is contraindicated in patients who are allergic to it and in patients who are taking phosphodiesterase inhibitors for erectile dysfunction. (medscape.com)

Nitroglycerin relaxes blood vessels to boost blood flow, yet the mechanism by which the drug works has remained a matter of scientific controversy. (dukehealth.org)
The researchers found through studies in mice that the cellular powerhouses -- known as mitochondria -- break down nitroglycerin to release nitric oxide, thereby opening blood vessels and lowering blood pressure. (dukehealth.org)
Animals unable to process nitroglycerin continued to respond to alternative nitrate drugs that dilate blood vessels, suggesting that those drugs work through an independent mechanism. (dukehealth.org)
As reported in the August 23 Proceedings of the National Academy of Sciences, the researchers found that the cellular powerhouses called mitochondria break down nitroglycerin to release nitric oxide, thereby opening blood vessels and lowering blood pressure. (duke.edu)
The main work of Nitroglycerin is to dilate the blood vessels, whereas Viagra's main function is to inh i bit PDE5 enzymes. (fordailymedicine.com)
Nitroglycerin helps release Nitric Oxide in the body, which causes blood vessels to dilate. (fordailymedicine.com)

The use of Viagra with Nitroglycerin in combination can cause Hypotension. (fordailymedicine.com)

In the present study, we combined masseter muscle tendon ligation (MMTL)-produced myogenic TMD with systemic injection of nitroglycerin (NTG)-induced migraine-like hypersensitivity in mice. (iasp-pain.org)

You should not take Viagra if you have a heart condition or a history of stroke, or if you are taking nitrate drugs (such as nitroglycerin or isosorbide dinitrate/mononitrate, used to treat chest pain). (vapharmacy.org)
Furthermore, he added, patients taking nitroglycerin should perhaps avoid taking other classes of drugs that also inhibit activity of the mitochondrial enzyme. (dukehealth.org)
The researchers also cautioned that patients on nitroglycerin should avoid taking other drugs that inhibit activity of the critical mitochondrial enzyme, called mtALDH, which is key to nitroglycerin's action. (duke.edu)

Each metered spray of Nitrolingual Pumpspray delivers 48 mg of solution containing 400 mcg of nitroglycerin after an initial priming of five sprays. (nih.gov)

Though it was previously known that these beneficial effects are due to nitroglycerin being converted to nitric oxide, a potent venodilator, the enzyme for this conversion was only discovered to be mitochondrial aldehyde dehydrogenase (ALDH2) in 2002. (wikipedia.org)

Nitroglycerin comes as a sublingual tablet to take under the tongue. (medlineplus.gov)
He was given a sublingual nitroglycerin tablet by the ambulance crew, and 5 minutes later, he rated his chest pain as 1 on the same scale. (hcplive.com)
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Ask your health care provider if Nitroglycerin may interact with other medicines that you take. (novalarpharm.com)
It can interact with other medicines, like Nitroglycerin. (fordailymedicine.com)

Nitroglycerin was adopted as a commercially useful explosive by Alfred Nobel, who experimented with safer ways to handle the dangerous compound after his younger brother, Emil Oskar Nobel, and several factory workers were killed in an explosion at the Nobels' armaments factory in 1864 in Heleneborg, Sweden. (wikipedia.org)
Discovered by Italian chemist Ascanio Sobrero in 1847 and perfected as a blasting agent by Alfred Nobel in the early 1860s, nitroglycerin was not widely known by the general public until accounts of accidental explosions like the one in San Francisco were printed in newspapers. (lindahall.org)
First discovered in 1847 and brought to public prominence by the famed Alfred Nobel, who manufactured it first as an explosive, nitroglycerin is a common treatment for chest pain and heart failure. (dukehealth.org)

Some medicines can affect how nitroglycerin works. (stlukes-stl.com)
Some medicines may interact with Nitroglycerin. (novalarpharm.com)

He began treating his patients with small diluted doses of nitroglycerin in 1878, and this treatment was soon adopted into widespread use after Murrell published his results in the journal The Lancet in 1879. (wikipedia.org)
Nitroglycerin may not work as well after you have used it for some time or if you have taken many doses. (medlineplus.gov)

Discovered in 1847 by Ascanio Sobrero, nitroglycerin has been used as an active ingredient in the manufacture of explosives, namely dynamite, and as such it is employed in the construction, demolition, and mining industries. (wikipedia.org)

Doctors have prescribed nitroglycerin for the relief of chest pain for some 150 years, yet the mechanism by which the drug works has remained a matter of debate," said study author Jonathan Stamler, M.D., at Duke. (dukehealth.org)
Now professor of medicine Jonathan Stamler and his colleagues have pinpointed the active mechanism of nitroglycerin. (duke.edu)

Nitroglycerin is used to prevent chronic chest pain caused by heart disease. (pharm-europe.com)

The current study finds that mtALDH is both necessary and sufficient for generating vasodilation from clinically relevant levels of nitroglycerin," Stamler said. (dukehealth.org)

Is Nitroglycerin like Viagra? (fordailymedicine.com)
No, you must not take Viagra and Nitroglycerin together. (fordailymedicine.com)
It may result in a Nitroglycerin and Viagra interaction . (fordailymedicine.com)
The best way to avoid the interaction of Viagra and Nitroglycerin is not to take them together. (fordailymedicine.com)

nitroglycerin IV increases effects of cabergoline by decreasing metabolism. (medscape.com)
nitroglycerin IV increases effects of ergotamine by decreasing metabolism. (medscape.com)

Nitroglycerin was invented in 1847 and displaced gunpowder as the most powerful explosive in the world. (yahoo.com)

Nitroglycerine was a new product in 1866. (lindahall.org)

nitroglycerin IV, tadalafil. (medscape.com)
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Nitroglycerin loses its effects on blood flow in animals lacking a particular mitochondrial enzyme called aldehyde dehydrogenase (mtALDH), the Duke team reported in the August 23, 2005, Proceedings of the National Academy of Sciences (published early online the week of August 15). (dukehealth.org)

Durham, N.C. -- Definitive evidence to explain how the drug nitroglycerin relieves chest pain has resulted from a new study by Howard Hughes Medical Institute investigators at Duke University Medical Center. (dukehealth.org)

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If your nitroglycerin supply is past its expiration date, get a new prescription as soon as you can. (cloudapp.net)
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Instruct the patient to administer one or two metered sprays (400 mcg of nitroglycerin per spray) at the onset of an attack onto or under the tongue. (nih.gov)
Keep nitroglycerin pills and liquid spray away from heat or moisture. (cloudapp.net)

Effect of nitroglycerin on peripheral blood flow distribution and venous return. (aspetjournals.org)

12 μg intracoronary nitroglycerin in seven dogs depressed only the deep contractile force without changing systemic hemodynamics. (jci.org)

The effects of both intracoronary and intravenous administration of nitroglycerin on transmural distribution of blood flow in the left ventricle after partial coronary artery occlusion was investigated using two independent methods. (jci.org)

This business exported a liquid combination of nitroglycerin and gunpowder called "Blasting Oil", but this was extremely unstable and difficult to handle, as evidenced in numerous catastrophes. (wikipedia.org)

These images are a random sampling from a Bing search on the term "Long Acting Nitroglycerin. (fpnotebook.com)

Our Nitrostat (nitroglycerin) (nitroglycerin) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. (rxlist.com)
It can be dangerous if your nitrate medication, such as nitroglycerin, is prescribed for chest pain or high pressure. (vapharmacy.org)

Sympathetic crashing acute pulmonary edema: Role of nitroglycerin infusion. (bvsalud.org)

Store nitroglycerin pills in a dark-colored (such as brown), airtight, glass container that you can't see through. (cloudapp.net)
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Anatomy6

Organisms1

Diseases7

Chemicals and Drugs22

Analytical, Diagnostic and Therapeutic Techniques and Equipment10

Phenomena and Processes11

Health Care1

Ointment6

Nitrates4

Vasodilator6

Sublingual tablets3

Less responsive to nitroglycerin2

Receiving nitroglycerin transdermal1

Physician William Murrell experimented2

Glyceryl1

Sildenafil3

Crates of nitroglycerin2

Effects of nitroglycerin3

Take nitroglycerin3

Liquid nitroglycerin3

Intravenous nitroglycerin1

Dilates2

Angina pectoris1

Transdermal patch1

Vardenafil1

Tablets2

Medications4

Dose7

Allergic3

Blood vessels6

Hypotension1

Injection1

Drugs3

NITROLINGUAL1

Nitric1

Tablet6

Interact with other medicines2

Alfred Nobel3

Medicines2

Doses2

Ingredient1

Mechanism2

Chest pain caused by heart disease1

Vasodilation1

Viagra4

Metabolism2

18471

18661

Tadalafil2

Mitochondrial1

Relieves1

Prescription3

Spray2

Peripheral1

Systemic1

Coronary1

Gunpowder1

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Medication2

Acute1

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