• It has become a prevalent technology, allowing an efficient genome-wide relative quantification of gene expression and, in particular, it is the method of choice to find differentially expressed genes between two or more biological conditions of interest. (frontiersin.org)
  • Differential gene expression analysis was performed with DESeq2, EdgeR, and Limma-Voom, and differentially expressed genes were annotated using BiomaRt. (pitt.edu)
  • All bioinformatics were conducted in R. There were 13827 differentially expressed genes, including ACTB and GADPH (housekeeping genes), identified in this study. (pitt.edu)
  • Among various differentially expressed genes identified, ASAP1, a gene not previously associated with prostate cancer, was upregulated in the metastatic subline as confirmed by qRT-PCR and immunohistochemical staining. (ubc.ca)
  • On average, we identify 43 mutations per tumour, excluding four cases with a mutator phenotype that harboured inactivating mutations in mismatch repair genes. (nih.gov)
  • In addition to mutations in TP53 and KRAS, we identify genetic alterations in chromatin remodelling genes, ARID1A and ARID1B, in histone methyltransferase MLL3, in histone deacetylase modifier SPOP and in chromatin assembly factor BAZ1A, in nearly two thirds of cases. (nih.gov)
  • It is a rare form of congenital adrenal hyperplasia (CAH) resulting from loss-of-function mutations involving the CYP17 gene. (medscape.com)
  • Changes in your genes are also called mutations or variants . (medlineplus.gov)
  • [ 6 ] Ibrutinib has demonstrated efficacy as monotherapy for rituximab-resistant cases, especially those with mutations in the MYD88 gene. (medscape.com)
  • Gene therapies "fix" genetic mutations by replacing or changing a gene that doesn't work with one that does. (medlineplus.gov)
  • These treatments "fix" the genetic mutations (harmful changes) that cause some diseases by replacing or changing a gene that doesn't work with one that does. (medlineplus.gov)
  • In some rare diseases, DNA mutations cause a gene or protein to work incorrectly. (medlineplus.gov)
  • Some muscular dystrophies are caused by mutations in genes that make important muscle proteins. (medlineplus.gov)
  • These results indicate that library preparation influences differential gene expression analysis and subsequently affects the downstream analyses that investigate the biological pathways impacted by gene expression level. (pitt.edu)
  • To identify metastasis-associated genes, differential gene expression analysis of metastatic PCa1-met and non-metastatic PCa2 prostate cancer sublines was carried out. (ubc.ca)
  • Ann Arbor District Library , 2023. (aadl.org)
  • Thank you to community members for passing the 2023 Eugene Parks and Rec Operations and Maintenance Levy 20-343. (flyeug.com)
  • mGene is a computational tool for the genome-wide prediction of protein coding genes from eukaryotic DNA sequences. (plob.org)
  • 27 and Gene Luen Yang, May 4 at Central Library, 6-8 p.m. (arlingtonva.us)
  • 27), creator of " New Kid ," and the Library of Congress' fifth National Ambassador for Young People's Literature, Gene Luen Yang (May 4), author of " Dragon Hoops . (arlingtonva.us)
  • On May 4, join us for a conversation between New York Times bestselling author Gene Luen Yang and Librarian Jennifer Santure about Yang's graphic novel career, from " American Born Chinese " to his latest graphic novel, " Dragon Hoops . (arlingtonva.us)
  • The Eugene Public Library is a municipal public library in Eugene, Oregon, United States. (wikipedia.org)
  • Eugene Public Library was established as a tax-supported entity in 1904. (wikipedia.org)
  • Eugene Public Library 25 years old Thursday. (wikipedia.org)
  • Remember all the hype last fall in The Register-Guard and local TV news that crime downtown was frightening people away from the Eugene public library? (eugeneweekly.com)
  • The Kansas City Public Library hosts author Eugene Halton for his ruminations on the battle between autonomy and automation as presented in his book The Great Brain Suck and Other American Epiphanies on Thursday, January 8 , at 6:30 p.m. at the Central Library , 14 W. 10th St. (kclibrary.org)
  • Come explore at the Library's three locations - Downtown, Bethel, and Sheldon - or 24/7 at the Eugene Public Library website . (flyeug.com)
  • Arlington Reads is made possible thanks to the generous support of the Friends of the Arlington Public Library . (arlingtonva.us)
  • I think my interest in information was, sort of like, inbred in the sense that I was fortunate when I was a child to live across the street from a branch of the New York Public Library. (webofstories.com)
  • The person Hackman, Gene represents an individual (alive, dead, undead, or fictional associated with resources found in Portland Public Library . (portlandlibrary.com)
  • Structured data from the Bibframe namespace is licensed under the Creative Commons Attribution 4.0 International License by Portland Public Library. (portlandlibrary.com)
  • Those who wish to become Egan volunteers, the center asks you to note that upcoming training sessions are noon Wednesday, Nov. 13, at the Eugene Public Library, Bascom-Tykeson room and 7 pm Wednesday, Nov. 13, 7 pm at Temple Beth Israel, 1175 E 29th Avenue in Eugene. (eugeneweekly.com)
  • RNA-Seq is a widely used technology that allows an efficient genome-wide quantification of gene expressions for, for example, differential expression (DE) analysis. (frontiersin.org)
  • One promising approach uses an injection of small, harmless viruses to deliver therapeutic dystrophin-producing genes directly into cells in the muscle. (medlineplus.gov)
  • If the ultimate aim understands the control of protein production for a particular gene or its architecture, then genomic libraries must be used. (biologydiscussion.com)
  • But the abnormal BCR-ABL1 gene has instructions for an abnormal protein. (medlineplus.gov)
  • Some medicines target the protein made by the BCR-ABL1 gene. (medlineplus.gov)
  • Nusinersen targets another gene called SMN2 that also makes a small amount of the SMN protein. (medlineplus.gov)
  • It helps muscles and nerves work properly by changing the SMN2 gene product to make more of the SMN protein than it usually would. (medlineplus.gov)
  • This remained the main library building until it was moved to its current location at West 10th Avenue and Charnelton Street in 2002. (wikipedia.org)
  • Free parking is available in the Library District Parking Garage at 10th and Baltimore. (kclibrary.org)
  • As a publicly supported institution, the Library generally does not own rights to material in its collections. (loc.gov)
  • The Digital Library strives to provide access to its collections and resources to the Villanova University community and the global community of scholars, subject to any intellectual property or other restrictions on use. (villanova.edu)
  • The Veterans History Project (VHP) at the Library of Congress collects, preserves and makes accessible the firsthand recollections of U.S. military veterans who served from World War I through more recent conflicts and peacekeeping missions, so that future generations may hear directly from veterans and better understand what they saw, did and felt during their service. (loc.gov)
  • John P. Snodgrass (AFC 2001/001/[VHP collection]), Veterans History Project Collection, American Folklife Center, Library of Congress. (loc.gov)
  • Chronicling America is sponsored jointly by the National Endowment for the Humanities external link and the Library of Congress. (loc.gov)
  • The focus of this collection is Americana and Cartographic Treasures of the Library of Congress. (libguides.com)
  • Names are selected from controlled lists used by the Library of Congress. (loc.gov)
  • Employment in Lane County (Eugene metropolitan statistical area). (or.us)
  • According to information from Egan, "Egan Warming Center's official season starts Nov 15, but with temperatures tonight expected to drop to 24 degrees tonight, St. Vincent de Paul is working with the city of Eugene and Lane County to open one warming center at Wheeler. (eugeneweekly.com)
  • A press release from the city of Eugene and Lane County adds that the Wheeler Pavilion can only accommodate adults age 18 and older. (eugeneweekly.com)
  • The Genetics Virtual Library provides links to Internet resources covering genetics in the biosciences. (bvsalud.org)
  • The use of expression levels of transcription factor-encoding genes according to hierarchical anatomical classifications covering different tissues and cell types makes it possible to filter out irrelevant binding site predictions and to identify candidates of potential functional importance for further experimental testing. (lu.se)
  • A BCR-ABL1 genetic test uses a sample of blood or bone marrow to look for an abnormal gene called BCR-ABL1 . (medlineplus.gov)
  • An abnormal BCR-ABL1 gene is an acquired genetic change. (medlineplus.gov)
  • If your health care provider thinks you may have a type of leukemia that involves the BCR-ABL1 gene , you may need a BCR-ABL1 genetic test to make a diagnosis. (medlineplus.gov)
  • As of December 14, The National Library of Medicine's Genetic Testing Registry lists 76,546 genetic tests for 22,570 conditions involving 18,736 genes and 518 laboratories. (cdc.gov)
  • Immune Response Is Key to Genetic Mechanisms of SARS-CoV-2 Infection With Psychiatric Disorders Based on Differential Gene Expression Pattern Analysis. (cdc.gov)
  • Since its discovery, the mcr-1 gene has been reported from Africa, Asia, Europe, South America, and North America ( 2 , 3 ), including the United States, where it has been identified in Escherichia coli isolated from three patients and from two intestinal samples from pigs ( 2 , 4 - 6 ). (cdc.gov)
  • Find this title in Libby, the library reading app by OverDrive. (overdrive.com)
  • And, my first experience with title scanning was in the library where I used to go in, in the forbidden section which was the adult part of the library, not the children's section which I rarely visited, I didn't read too many children's books when I was a child, and I scanned the title of every book in the library. (webofstories.com)
  • No tags from this library for this title. (who.int)
  • Gene R. Dahl currently has 1 title listed in the Library. (shadolibrary.org)
  • Title : Nitroreductase-Activatable Morpholino Oligonucleotides for in Vivo Gene Silencing Personal Author(s) : Yamazoe, Sayumi;McQuade, Lindsey E.;Chen, James K. (cdc.gov)
  • In 1906, Oregon's first Carnegie Library was established on the corner of Willamette Street and East 11th Avenue. (wikipedia.org)
  • In 2003 the new library building won first place in the American Institute of Architects of Southwest Oregon's public architecture awards. (wikipedia.org)
  • Eugene is Oregon's second largest city, and it is known for its education, recreation, and attractions. (citytowninfo.com)
  • With spa jets revving and current channel circulating, Sheldon Pool & Fitness Center reopened its doors on September 26, 2022, to the Eugene community. (flyeug.com)
  • However, when applying this concept to genomes of multicellular organisms such as mammals, one has to deal with a large number of false positive predictions since many transcription factor genes are only expressed in specific tissues or cell types. (lu.se)
  • TS-REX was applied to predict regulators of Polycomb group genes in six human tumor tissues and in human embryonic stem cells. (lu.se)
  • By digesting complex genomic DNA from an organism it is possible to reproducibly divide its genome into a large number of small fragments, each approximately the size of a single gene. (biologydiscussion.com)
  • Most rare diseases (almost 80%) are caused by a defect in a single gene. (medlineplus.gov)
  • At this time, the library already had two branches-Bethel (West Eugene) and Sheldon (Cal Young neighborhood)-that had opened in 2000. (wikipedia.org)
  • Eugene Garfield (1925-2017) was an American scientist and publisher. (webofstories.com)
  • It was big news this week when scientist He Jiankui announced at the Second International Summit on Human Genome Editing that he'd "CRISPR'd" genes in embryos of twin girls. (gale.com)
  • While you're in Science In Context , you can listen to NPR's reporting from just days ago, Chinese Scientist Says He's Created First Genetically Modified Babies , and read all about this subject in articles in The Washington Post , The peril and promise of gene editing , and Scientist's claim of gene-edited babies creates uproar . (gale.com)
  • and a cDNA library, which represents the mRNA from a cell or tissue at a specific point of time. (biologydiscussion.com)
  • Join us on a tour of the newly renovated and expanded Campbell Community Center, thanks to funding from the 2018 Parks and Recreation Bond that was passed by Eugene voters. (flyeug.com)
  • The mcr-1 gene was first reported in 2015 in food, animal, and patient isolates from China ( 1 ) and is notable for being the first plasmid-mediated colistin resistance mechanism to be identified. (cdc.gov)
  • Alterations in genes with potential clinical utility are observed in more than three quarters of the cases and included members of the PI3-kinase and homologous DNA repair pathways. (nih.gov)
  • namely, metabolic pathways, regulatory pathways, and molecular assemblies, and maintains gene catalogs for all the organisms that have be. (bvsalud.org)
  • The graphic novel character Gene understands stories-comic book stories featuring action and heroes, in particular. (arlingtonva.us)
  • With our three pools and seven community centers, it's Eugene Rec's mission to provide recreation opportunities to all Eugene residents for sharp minds and strong bodies. (flyeug.com)
  • Floating down the river of evolution-time, Library (PHIL), Centers for In the landscape of gene-space. (cdc.gov)
  • While scientifically fascinating, altering genes for different purposes creates ethical conundrums, with potentially wide-spread implications. (gale.com)
  • The fully developed version shows the best overall performance compared to the submitted gene finders' predictions, including the ones of Fgenesh and Augustus. (plob.org)
  • After a brief review of the main issues, methods and tools related to the DE analysis of RNA-Seq data, this article focuses on the impact of both the replicate number and library size in such analyses. (frontiersin.org)
  • NIH-supported researchers have been studying ways to deliver dystrophin genes to affected muscles with fewer side effects. (medlineplus.gov)
  • The maps and much more detail on the land supply, demand and capacity analysis are included in the Envision Eugene Employment Land Supply Study and Residential Land Supply Study , both appendices to the 2017 adopted Envision Eugene Comprehensive Plan . (eugene-or.gov)
  • As a global trend, we concluded that the replicate number has a larger impact than the library size on the power of the DE analysis, except for low-expressed genes, for which both parameters seem to have the same impact. (frontiersin.org)
  • We also analyzed the impact of both the replicate number and library size on gene ontology (GO) enrichment analysis. (frontiersin.org)
  • Interestingly, we concluded that increases in the replicate number and library size tend to enhance the sensitivity and specificity, respectively, of the GO analysis. (frontiersin.org)
  • For individuals working on tomato research, on the basis of the meta-analysis, we recommend at least four biological replicates per condition and 20 M reads per sample to be almost sure of obtaining about 1000 DE genes if they exist. (frontiersin.org)
  • did not significantly alter the sustained, elevated FVIII levels, and multiplex gene expression analysis revealed the upregulation of biomarkers associated with immune tolerance signaling, post-dosing. (wfu.edu)
  • We developed TS-REX, a database/software system that supports the analysis of tissue and cell type-specific transcription factor-gene networks based on expressed sequence tag abundance of transcription factor-encoding genes in UniGene EST libraries. (lu.se)
  • Plasmids can be transferred between bacteria, potentially spreading the resistance gene to other bacterial species. (cdc.gov)
  • The bacterial population structure of waste before and after treatment was monitored using 16S rRNA gene sequence libraries. (cdc.gov)
  • Organización molecular del complejo II y su rol en la anaerobiosis. (bvsalud.org)
  • It offers pre-trained models for the recognition of gene structures including untranslated regions in an increasing number of organisms. (plob.org)
  • On April 27, join us for a conversation between author Jerry Craft and Library Division Chief Peter Petruski about Jerry Craft's novel " New Kid ," and his newest installment " School Trip . (arlingtonva.us)
  • The heterogeneity of primary prostate cancer specimens from patients, consisting of non-metastatic and metastatic subpopulations, hampers identification of metastasis-associated genes by direct comparison of primary and secondary cancers. (ubc.ca)
  • Library visits were up 21 percent last year, the largest increase in five years, according to the library’s recent annual report . (eugeneweekly.com)
  • Because of this, gene therapies - treatments where certain genes are adjusted to treat someone's disease - are a promising approach for some diseases. (medlineplus.gov)
  • There's no cure for DMD, but there are treatments that can help with the symptoms, including gene-based therapies that help the muscles make more dystrophin. (medlineplus.gov)
  • In 2005, the Eugene City Council adopted and applied the /WR Water Resources Conservation Overlay Zone measures to implement statewide planning Goal 5 inside Eugene's city limits. (eugene-or.gov)
  • Eugene Schieffelin, a New York City pharmacist and drug manufacturer, was born Jan. 29, 1827. (lindahall.org)
  • Biking is hugely popular in Eugene, and the city has 28 miles of off-street paths, 78 miles of on-street bicycle lanes, and 4 bicycle bridges that cross the Willamette River. (citytowninfo.com)
  • Eugene City Brewing has a lunch and dinner menu and features Rogue Ales on tap. (citytowninfo.com)
  • Open Library is an initiative of the Internet Archive , a 501(c)(3) non-profit, building a digital library of Internet sites and other cultural artifacts in digital form. (openlibrary.org)
  • If you are experiencing difficulties in accessing, viewing, or navigating the Digital Library, please contact us at [email protected] or 610.519.5271. (villanova.edu)
  • The Register-Guard (Eugene, Oregon). (wikipedia.org)
  • Eugene, Oregon. (wikipedia.org)
  • KVAL News (Eugene, Oregon). (wikipedia.org)
  • Welcome to University Inn & Suites, a 100% smoke-free, family-friendly Eugene, Oregon hotel located directly across from Matthew Knight. (lyft.com)
  • Eugene, Oregon enjoys a reputation as one of the most livable cities in the United States. (citytowninfo.com)
  • Sports in Eugene are very much focused on the Oregon Ducks, which are members of the Pacific 10 Conference. (citytowninfo.com)
  • Eugene is also known as the "Track Capital of the World," with Bill Bowerman coaching the champion University of Oregon track team and U of O alumni Phil Knight founding Nike, Inc. There is a Nike store in Eugene that features a track history museum. (citytowninfo.com)
  • Part of the Oregon Index compiled by Oregon State Library staff and volunteers. (or.us)
  • This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. (or.us)
  • to enable sorting into primary and secondary data for competing lineages of the same gene. (cdc.gov)
  • The Neighborhood Planning Guidelines are intended to serve as a resource to residents interested in addressing local concerns and aspirations through a planning process and describe the framework for neighborhood planning in Eugene. (eugene-or.gov)
  • including which interferon-stimulated gene (ISGs) directly inhibit Toxoplasma in pig cells. (usda.gov)
  • See how well your treatment is working (if treatment is helping, the number of cells with BCR-ABL1 genes will decrease. (medlineplus.gov)
  • All 10x Genomic services include a final report containing a Cell Ranger web summary file for quality control (QC) of the sequencing outcome, as well as FASTQ, BAM, gene count matrix containing all single cells or nuclei passing QC, basic visualization and clustering. (lu.se)
  • Extra ASAP1 gene copies were detected in 58% of primary prostate cancer specimens. (ubc.ca)
  • Despite a global pandemic and historic wildfires, the Eugene Parks and Recreation bond and levy work continued. (flyeug.com)
  • Eugene has an extensive system of outdoor parks for the public to enjoy. (citytowninfo.com)
  • A gene-specific T2A-GAL4 library for Drosophila . (bvsalud.org)
  • There's another gene-based therapy for children under age 2 that uses a safe virus to deliver a new copy of the SMN gene into specific neurons to improve muscle movement. (medlineplus.gov)
  • In an attempt to clone some specific parasite antigen genes, a Trypanosoma cruzi cDNA library was constructed in lambda gt11. (bvsalud.org)
  • Library, Recreation & Cultural Services Annual Report 2010" (PDF). (wikipedia.org)
  • The Library, Recreation and Cultural Services Department (LRCS) takes quality of life seriously. (flyeug.com)