Recent evidence from Malawi shows that 3 months of post-discharge malaria chemoprevention (PMC) with monthly treatment with artemether-lumefantrine in children with severe malarial anaemia prevented 31% of deaths and readmissions. (uib.no)
Post-discharge malaria chemoprevention (PMC) is the intermittent administration of full treatment courses of antimalarial to children recovering from severe anaemia and findings suggest that this intervention significantly reduces readmissions and deaths in these children. (biomedcentral.com)
Post-discharge malaria chemoprevention with DHP is perceived as a positive approach to manage children recovering from severe anaemia by HSAs in Malawi. (biomedcentral.com)
Post-discharge malaria chemoprevention (PMC) is the intermittent administration of full treatment courses of antimalarial to children recovering from severe anaemia. (biomedcentral.com)
Projected health impact of post-discharge malaria chemoprevention among children with severe malarial anaemia in Africa. (bvsalud.org)
However, a recent trial found that post-discharge malaria chemoprevention (PDMC) with dihydroartemisinin-piperaquine reduces this risk . (bvsalud.org)
Seasonal18
BACKGROUND: Seasonal malaria chemoprevention (SMC) is a new strategy recommended by WHO in areas of highly seasonal transmission in March 2012. (rti.org)
Since 2013, Malaria Consortium has led the distribution of seasonal malaria chemoprevention (SMC) - a safe, feasible, effective and cost-effective intervention for preventing malaria among children under five - in Nigeria. (malariaconsortium.org)
Seasonal malaria chemoprevention, previously known as intermittent preventive treatment in children, is highly effective in areas with a short malaria transmission season. (scienceopen.com)
We then use spatial rainfall, malaria endemicity and population data to identify areas likely to have highly seasonal malaria incidence, and estimate the population at risk and malaria burden in areas where seasonal malaria chemoprevention would be appropriate. (scienceopen.com)
We estimate that in areas suitable for seasonal malaria chemoprevention, there are 39 million children under 5 years of age, who experience 33.7 million malaria episodes and 152,000 childhood deaths from malaria each year. (scienceopen.com)
Our data suggest that seasonal malaria chemoprevention has the potential to avert several million malaria cases and tens of thousands of childhood deaths each year if successfully delivered to the populations at risk. (scienceopen.com)
Seasonal malaria chemoprevention can lower the incidence of malaria in areas where transmission is highly periodical. (scienceopen.com)
Seasonal malaria chemoprevention (SMC) is a relatively new and highly effective method of preventing malaria in children under five. (who.int)
Oyo state government has flagged off the second round of seasonal malaria chemoprevention distribution campaign in Saki west local government area of the state. (factualtimesng.com)
The second round of Seasonal Malaria Chemoprevention distribution will commence on Friday June 16th, 2023 and last till Monday 19th June, 2023. (factualtimesng.com)
On the Day of the African Child, Medicines for Malaria Venture (MMV) reflects on what 10 years of seasonal malaria chemoprevention has meant for young children in the Sahel, and how to protect more children going forward. (healthpolicy-watch.news)
The Day of the African Child is an opportunity to celebrate 10 years of seasonal malaria chemoprevention (SMC) and to draw attention to the fact that, despite the progress made against the disease, children in sub-Saharan Africa still bear the majority of the global burden. (healthpolicy-watch.news)
Seasonal malaria chemoprevention has saved thousands of lives of children under the age of five. (healthpolicy-watch.news)
Seasonal malaria chemoprevention (SMC) is effective to prevent malaria in children 3 to 59 months in the Sahel region. (bvsalud.org)
Mother 's seasonal malaria chemoprevention related knowledge and attitudes and the coverage of the strategy among targeted children were assessed. (bvsalud.org)
Mother's seasonal malaria chemoprevention related knowledge and attitudes and the coverage of the strategy among targeted children were assessed. (who.int)
Seasonal malaria chemoprevention (SMC) is a strategy medications to children aged 3 to 59 months during the which administers therapeutic doses of antimalarial period of high malaria transmission, to prevent them from *Corresponding author. (who.int)
Prostate3
Because prostate cancer has a long latency period and is typically diagnosed in elderly men, it represents an ideal candidate disease for chemoprevention. (umn.edu)
Chemoprevention of prostate cancer by teapolyphenols appears to occur through the modulation of various molecular targets. (umn.edu)
This article attempts to address the issue of the possible use of tea, especially green tea, for the chemoprevention of prostate cancer. (umn.edu)
At ACG 2018, Dr. Inadomi discussed the evidence for and against chemoprevention for malignancies of the gastrointestinal tract and provided recommendations for appropriate use. (gi.org)
Cervical cancer1
Chemoprevention of cervical cancer with folic acid: a phase III Southwest Oncology Group Intergroup study. (escholarship.org)
Colorectal2
The trials conducted on adults with pervious colorectal neoplasia whore treated with candidate chemoprevention drugs and placebo were selected. (physiciansweekly.com)
Carey, EJ & Lindor, K 2012, ' Chemoprevention of colorectal cancer with ursodeoxycholic acid: Cons ', Clinics and Research in Hepatology and Gastroenterology , vol. 36, no. (elsevierpure.com)
Preventive2
It is important to identify those at high risk, as there are now effective preventive strategies, such as chemoprevention therapy and risk-reduction surgery. (unito.it)
along with modifiable risk factors such as environmental, hormonal, and lifestyle factors The goal of preventing breast cancer is to identify high-risk individuals who would benefit most from preventive therapies such as chemoprevention and risk-reducing surgeries. (mhmedical.com)
Populations2
[ 1 ] The success of several clinical trials in cancer prevention in high-risk populations suggests that chemoprevention is a rational and appealing strategy. (medscape.com)
A health economic model was developed to assess the cost-effectiveness of chemoprevention for two populations with different levels of risk of developing CRC: the general population and an intermediate-risk population. (fapvoice.com)
Cancer22
CHEMOPREVENTION OF TOBACCO-RELATED CANCERS IN FORMER SMOKERS: CLINICAL STUDIES Release Date: March 28, 2002 RFA: CA-03-006 National Cancer Institute (NCI) ( http://www.nci.nih.gov/ ) LETTER OF INTENT RECEIPT DATE: June 21, 2002 APPLICATION RECEIPT DATE: July 26, 2002 This RFA is a reissue of RFA-CA-02-009 , which was published in the NIH Guide on 04/20/2001. (nih.gov)
Cancer chemoprevention, as first defined in 1976 by Sporn, is the use of natural, synthetic, or biologic chemical agents to reverse, suppress, or prevent carcinogenic progression. (medscape.com)
Cancer chemoprevention has earned serious consideration as a potential means of controlling cancer incidence, having become a top research priority of the National Cancer Institute (NCI). (medscape.com)
Secondary chemoprevention is targeted at patients with cancer who, in order to prevent recurrent disease or to prevent metachronous primary diseases, have undergone potentially curative therapy. (medscape.com)
The basic cancer-related chemical and biologic sciences, pathology, and epidemiology have contributed to (1) the understanding that antimutagenesis and antiproliferation are the important general mechanisms of chemoprevention and (2) the development of antimutagenic and antiproliferative agents as potential chemopreventive drugs. (medscape.com)
Chemoprevention is an appealing strategy with proven success in familial adenomatous polyposis (FAP) and breast cancer. (medscape.com)
Oral keratosis with atypia is an ideal model for the study of head and neck cancer development and chemoprevention because the lesions are readily accessible to visual examination, diagnostic sampling, and evaluation of response to treatment. (medscape.com)
In discussing chemoprevention in head and neck cancer, only histologic terminology allows significance. (medscape.com)
People who have a family history of breast cancer may consider chemoprevention to reduce their own risk of developing it. (guysandstthomas.nhs.uk)
Chemoprevention uses medicine to lower the risk of getting cancer, or the risk of it returning, in healthy people. (guysandstthomas.nhs.uk)
Chemoprevention is considered for people who have not developed cancer but have an increased risk of getting the disease due to their family history. (guysandstthomas.nhs.uk)
Chemoprevention is for people who have been assessed by a family history or genetics specialist and have a confirmed increased risk of developing breast cancer than in the general population. (guysandstthomas.nhs.uk)
People with BRCA or PALB2 mutations who have already had breast surgery (with or without reconstruction) to reduce the risk of cancer developing, are not eligible for chemoprevention. (guysandstthomas.nhs.uk)
The benefit of chemoprevention is significantly less than if you choose to have surgery to reduce your risk of developing breast cancer. (guysandstthomas.nhs.uk)
If you have been assessed as having an increased familial breast cancer risk (moderate, high or very high) you should continue with breast screening plans, even if you have chosen chemoprevention. (guysandstthomas.nhs.uk)
Tamoxifen is licensed for the purpose of chemoprevention at a dose of 20mg daily for 5 years, for people at a moderate to high risk of breast cancer. (guysandstthomas.nhs.uk)
Chemoprevention refers to the use of medication, vitamins, or supplements to stop the incidence of cancer, especially in people with a high risk of developing cancer. (physiciansweekly.com)
Our earlier studies had identified HDAC inhibitors as potential chemoprevention compounds for hereditary diffuse gastric cancer (HDGC) [1]. (nostomachforcancer.org)
Chemoprevention in LS with aspirin and nonsteroidal anti-inflammatory drugs has also translated into clinical cancer, however the efficacy of such agents in FAP remains elusive when cancer is applied as an endpoint in trials rather than the use of 'indirect' endpoints such as polyp burden, and requires further elucidation of biological mechanisms in FAP. (aacrjournals.org)
Chemoprevention can be defined as the use of natural or synthetic chemical agents to reverse, suppress, or prevent carcinogenic progression to invasive cancer. (mhmedical.com)
Cancer chemoprevention is very attractive and has earned serious consideration as a potential means of controlling cancer incidence. (medscape.com)
Identify PCPs' awareness of breast cancer risk assessment and breast cancer chemoprevention knowledge, and identify perceived barriers and clinic solutions. (sutterhealth.org)
Perennial1
MA145 trade name] is also indicated for perennial malaria chemoprevention of children at high risk of severe malaria in areas of moderate to high perennial malaria transmission, where sulfadoxine- pyrimethamine is effective. (who.int)
Interventions1
The current package of core interventions - namely, vector control, chemoprevention, diagnostic testing and treatment - has proved to be highly cost-effective and needs to be further expanded in order to save more lives. (who.int)
Strategies1
To explore the joint toxicity and bio-accumulation of multi-heavy metals and potential chemoprevention strategies, Male Sprague Dawley (SD) rats (n = 30) were treated orally once a week for six months with 500mg/kg.bw of eight heavy metals which were commonly identified in aquatic products in the Ningbo area including chromium, manganese , nickel, copper, zinc, cadmium, mercury, and lead. (cdc.gov)
Lesions2
Primary chemoprevention is directed at patients with premalignant lesions (mucosal keratosis with atypia and erythroplakia). (medscape.com)
Data show that chemoprevention with selective cyclooxygenase-2 (COX-2) inhibitors, particularly celecoxib ( Celebrex , GD Searle), can reduce the incidence of these lesions. (medscape.com)
Feasible1
The proposed study will help to identify the most effective, cost-effective, acceptable and feasible strategy for delivering malaria chemoprevention for post-discharge management of severe anaemia in under-five children in the Malawian context. (uib.no)
Polyphenols1
This review will present the available data for standardized green teapolyphenols in regard to PCa chemoprevention that will include epidemiological, mechanism based studies, safety, pharmacokinetics, and applicable clinical trials. (breakawaymatcha.com)
Attitudes1
A separate search identified qualitative studies relating to individuals' views, attitudes and beliefs about chemoprevention. (fapvoice.com)
Dr Adeyanju said children within the age bracket are expected to take chemoprevention drugs on monthly basis for five months. (factualtimesng.com)
Rats1
Joint toxicity of a multi-heavy metal mixture and chemoprevention in Sprague Dawley rats. (cdc.gov)
Drugs1
We have now tested several HDAC inhibitors in this and other related models and identified two promising HDAC inhibitors for further development as HDGC chemoprevention drugs. (nostomachforcancer.org)
Potential2
But now a potential biomarker that identifies individuals who would derive most benefit has been found, which would personalize use of such chemoprevention. (medscape.com)
EGCG, TCD or GSH all showed certain chemoprevention effects against the joint toxicity induced by the multi-heavy metal mixture and indicated alleviation and the potential mechanism that also included the promotion of excretion of metals to which animals were exposed. (cdc.gov)
Primary1
Chemoprevention can be categorized as either primary chemoprevention or secondary chemoprevention. (medscape.com)
Risk3
Chemoprevention can reduce the risk of oestrogen positive cancers happening. (guysandstthomas.nhs.uk)
Chemoprevention was assessed in the general population, in individuals at increased risk of CRC, and in individuals with FAP or HNPCC. (fapvoice.com)
The data that has been collected so far suggests that green tea may be a promising agent for PCa chemoprevention and further clinical trials of participants at risk of PCa or early stage PCa are warranted. (breakawaymatcha.com)
Agents1
However, there has been some hesitation over the use of celecoxib and related agents for chemoprevention because of concern over cardiovascular risks, as well as other possible side effects. (medscape.com)
Distribution1
He urged stakeholders in concerned communities to ensure successes of the Chemoprevention Distribution Campaign. (factualtimesng.com)
Benefit1
The benefit of chemoprevention in people with BRCA or PALB2 mutations is uncertain. (guysandstthomas.nhs.uk)