Penta-O-galloyl-beta-D-glucose induces G1 arrest and DNA replicative S-phase arrest independently of cyclin-dependent kinase inhibitor 1A, cyclin-dependent kinase inhibitor 1B and P53 in human breast cancer cells and is orally active against triple negative xenograft growth.
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Knockdown of transient receptor potential canonical-1 reduces the proliferation and migration of endothelial progenitor cells.
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Polycomb protein EZH2 regulates cancer cell fate decision in response to DNA damage.
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A novel RING finger protein, Znf179, modulates cell cycle exit and neuronal differentiation of P19 embryonal carcinoma cells.
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Metformin induces G1 cell cycle arrest and inhibits cell proliferation in nasopharyngeal carcinoma cells.
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Control of Cdc14 activity coordinates cell cycle and development in Caenorhabditis elegans.
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Mitotic catastrophe occurs in the absence of apoptosis in p53-null cells with a defective G1 checkpoint.
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Androgens as therapy for androgen receptor-positive castration-resistant prostate cancer.
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