A plague-like disease of rodents, transmissible to man. It is caused by FRANCISELLA TULARENSIS and is characterized by fever, chills, headache, backache, and weakness.
The etiologic agent of TULAREMIA in man and other warm-blooded animals.
The genus Lepus, in the family Leporidae, order LAGOMORPHA. Hares are born above ground, fully furred, and with their eyes and ears open. In contrast with RABBITS, hares have 24 chromosome pairs.
The lone genus of bacteria in the family Francisellaceae, frequently found in natural waters. It can be parasitic in humans, other MAMMALS; BIRDS; and ARTHROPODS.
Suspensions of attenuated or killed bacteria administered for the prevention or treatment of infectious bacterial disease.
Pathological processes involving the PHARYNX.
I'm sorry for any confusion, but the term "Bulgaria" is not a medical concept or condition that has a defined meaning within the medical field. It is actually the name of a country located in southeastern Europe, known officially as the Republic of Bulgaria.
Diseases of LYMPH; LYMPH NODES; or LYMPHATIC VESSELS.
Live vaccines prepared from microorganisms which have undergone physical adaptation (e.g., by radiation or temperature conditioning) or serial passage in laboratory animal hosts or infected tissue/cell cultures, in order to produce avirulent mutant strains capable of inducing protective immunity.
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**I'm sorry for any confusion, but "Wyoming" is a U.S. state and not a term used in medical definitions.**
An order of small mammals comprising two families, Ochotonidae (pikas) and Leporidae (RABBITS and HARES). Head and body length ranges from about 125 mm to 750 mm. Hares and rabbits have a short tail, and the pikas lack a tail. Rabbits are born furless and with both eyes and ears closed. HARES are born fully haired with eyes and ears open. All are vegetarians. (From Nowak, Walker's Mammals of the World, 5th ed, p539-41)
The family of omnivorous New World skunks, showing typical warning coloration of patterned black and white and able to eject a malodorous secretion when the animal is startled or in danger.
Sudden increase in the incidence of a disease. The concept includes EPIDEMICS and PANDEMICS.
Tests that are dependent on the clumping of cells, microorganisms, or particles when mixed with specific antiserum. (From Stedman, 26th ed)
Diseases of non-human animals that may be transmitted to HUMANS or may be transmitted from humans to non-human animals.
The middle portion of the pharynx that lies posterior to the mouth, inferior to the SOFT PALATE, and superior to the base of the tongue and EPIGLOTTIS. It has a digestive function as food passes from the mouth into the oropharynx before entering ESOPHAGUS.
Pathological processes of the ear, the nose, and the throat, also known as the ENT diseases.
Immunoglobulins produced in a response to BACTERIAL ANTIGENS.
Inflammation of the lymph nodes.
A widely distributed genus of TICKS, in the family IXODIDAE, including a number that infest humans and other mammals. Several are vectors of diseases such as TULAREMIA; ROCKY MOUNTAIN SPOTTED FEVER; COLORADO TICK FEVER; and ANAPLASMOSIS.
The use of biological agents in TERRORISM. This includes the malevolent use of BACTERIA; VIRUSES; or other BIOLOGICAL TOXINS against people, ANIMALS; or PLANTS.
Created as the Kingdom of Serbs, Croats, and Slovenes in 1918. Yugoslavia became the official name in 1929. BOSNIA-HERZEGOVINA; CROATIA; and SLOVENIA formed independent countries 7 April 1992. Macedonia became independent 8 February 1994 as the Former Yugoslav Republic of Macedonia (MACEDONIA REPUBLIC).
Blood-sucking acarid parasites of the order Ixodida comprising two families: the softbacked ticks (ARGASIDAE) and hardbacked ticks (IXODIDAE). Ticks are larger than their relatives, the MITES. They penetrate the skin of their host by means of highly specialized, hooked mouth parts and feed on its blood. Ticks attack all groups of terrestrial vertebrates. In humans they are responsible for many TICK-BORNE DISEASES, including the transmission of ROCKY MOUNTAIN SPOTTED FEVER; TULAREMIA; BABESIOSIS; AFRICAN SWINE FEVER; and RELAPSING FEVER. (From Barnes, Invertebrate Zoology, 5th ed, pp543-44)
"Bites and stings refer to tissue damage or toxic reactions caused by the teeth, mouthparts, or venomous secretions of animals such as insects, spiders, snakes, and mammals during predatory or defensive attacks."
Inflammation of the tonsils, especially the PALATINE TONSILS but the ADENOIDS (pharyngeal tonsils) and lingual tonsils may also be involved. Tonsillitis usually is caused by bacterial infection. Tonsillitis may be acute, chronic, or recurrent.
A mammalian order which consists of 29 families and many genera.
The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.
whoa, I'm just an AI and I don't have the ability to provide on-the-fly medical definitions. However, I can tell you that "Missouri" is not a term commonly used in medicine. It's a state in the United States, and I assume you might be looking for a medical term that is associated with it. If you could provide more context or clarify what you're looking for, I'd be happy to help further!
Living outdoors as a recreational activity.

Rapid local expression of interleukin-12, tumor necrosis factor alpha, and gamma interferon after cutaneous Francisella tularensis infection in tularemia-immune mice. (1/568)

Francisella tularensis LVS is an effective live vaccine strain used for cutaneous vaccination against tularemia in man. In mice, injection of LVS causes invasive disease and subsequent development of immunity that is characterized by effective control of otherwise lethal doses of the organism. In the present investigation, it is shown that LVS-immune mice controlled an intradermal infection much more effectively than did naive mice; bacterial counts in skin samples were 1.5 to 2.0 log10 lower 24 h after injection and 6 log10 lower 72 h after injection in immune mice. Moreover, in contrast to naive mice, no bacteria were demonstrated in samples from livers and spleens of immune mice. By immunohistochemistry, skin samples from immune mice showed an intense staining for interleukin-12 (IL-12) and a moderate staining for tumor necrosis factor alpha (TNF-alpha) at 24 h postinoculation, after which staining for both cytokines faded. In naive mice, the staining for IL-12 was weak at all time points and no staining for TNF-alpha was observed. No staining for gamma interferon (IFN-gamma) was observed in any group before 72 h. At that time point, skin samples from immune mice showed moderate staining and skin samples from naive mice showed weak staining. Reverse transcriptase PCR showed an induction of mRNA of the three cytokines in the skin within the first day after injection. A quantitative analysis demonstrated higher IFN-gamma and TNF-alpha mRNA levels in immune mice at 24 h postinoculation. In conclusion, immunization with F. tularensis LVS conferred a capability to respond to cutaneous reinfection, with rapid local expression of IL-12, TNF-alpha, and IFN-gamma, and this expression was paralleled by containment and mitigation of the infection. The cytokine response may be part of a local barrier function of the skin, important to host protection against tularemia.  (+info)

Tularemia--an unusual cause of a solitary pulmonary nodule in the post-transplant setting. (2/568)

We report a case of tularemia presenting as a solitary pulmonary nodule following syngeneic PBSC transplant. Seven months after undergoing a syngeneic PBSC transplant for AML, our patient presented with fever without localizing signs. Chest X-ray revealed a solitary pulmonary nodule. Culture of a CT guided needle aspiration revealed Francisella tularensis. The patient was successfully treated with ciprofloxacin. His fever resolved and clearance of the nodule was documented on a CT scan 2 months after diagnosis and initiation of treatment. To our knowledge, this is the only reported case of tularemia occurring in the post-transplant setting. The possible relationship between transplant-induced immune dysfunction and the occurrence of this rare infection is discussed.  (+info)

Repeated administration of synthetic oligodeoxynucleotides expressing CpG motifs provides long-term protection against bacterial infection. (3/568)

Synthetic oligodeoxynucleotides (ODN) expressing unmethylated CpG motifs stimulate an innate immune response characterized by the production of polyreactive immunoglobulin M antibodies and immunomodulatory cytokines. This immune response has been shown to protect mice from challenge by Listeria monocytogenes and Francisella tularensis for up to 2 weeks. By repeatedly administering CpG ODN two to four times/month, we found that this protection could be maintained indefinitely. Protection was associated with a significant increase in the number of spleen cells that could be triggered by subsequent pathogen exposure to secrete gamma interferon and interleukin-6 in vivo (P < 0.01). ODN-treated animals remained healthy and developed neither macroscopic nor microscopic evidence of tissue damage or inflammation. Thus, repeated administration of CpG ODN may provide a safe means of conferring long-term protection against infectious pathogens.  (+info)

Treatment of tularemia with fluoroquinolones: two cases and review. (4/568)

Streptomycin, gentamicin, and tetracycline are currently considered the antimicrobials of choice for the treatment of tularemia. Preliminary data suggest that quinolones may be effective alternative agents; however, clinical experience is limited, and their role in treating severe disease is uncertain. We recently treated two acutely ill immunocompromised patients who had presumed "atypical" pneumonia with levofloxacin. Both patients had an excellent clinical response and were diagnosed with tularemia only when blood cultures subsequently yielded Francisella tularensis. Neither patient relapsed during 12 months of follow-up. Including our two cases, a total of 10 cases of tularemia treated with quinolones have been reported. In all 10 cases, a favorable clinical response was documented, and no relapses occurred. We conclude that the quinolones appear promising for the treatment of even severe tularemia, and they should be considered efficacious alternative agents for patients who do not require parenteral therapy or are intolerant of more standard treatment regimens.  (+info)

Comparative analysis of PCR versus culture for diagnosis of ulceroglandular tularemia. (5/568)

PCR and culture were comparatively evaluated for their abilities to demonstrate Francisella tularensis in wound specimens from tularemia patients during an outbreak in Sweden in 1998. For transport of the specimens used for PCR, a buffer solution containing a nuclease inhibitor was used, and for transport of the specimens used for culture, a commercial transport system was selected after experimental comparison of various systems. Of 40 patients with culture- and/or serology-verified ulceroglandular tularemia, PCR detected F. tularensis DNA in 30 (75%) patients, whereas culture detected bacterial growth in 25 (62%) patients. Compared to data from a previous study, the present inclusion of a nuclease inhibitor in the transport medium did not improve the sensitivity of the PCR, whereas the sensitivity of the culture procedure was significantly increased by selection of the system used for transport. Among eight patients with clinically suspected tularemia but with negative serology and culture, specimens from four patients showed detectable DNA. In three of these patients the diagnosis was verified by the demonstration of an F. tularensis-specific T-cell response in vitro. In conclusion, PCR was more sensitive than culture for demonstration of F. tularensis in wound specimens. Besides, we showed that tularemia may proceed without development of serum antibodies, and in these patients, PCR may be of special importance for verification of the diagnosis.  (+info)

Influence of the bcg locus on natural resistance to primary infection with the facultative intracellular bacterium Francisella tularensis in mice. (6/568)

The implication of the Bcg locus in the control of natural resistance to infection with a live vaccine strain (LVS) of the intracellular pathogen Francisella tularensis was studied. Analysis of phenotypic expression of natural resistance and susceptibility was performed using mouse strains congenic at the Bcg locus. Comparison of the kinetics of bacterial colonization of spleen showed that B10.A.Bcg(r) mice were extremely susceptible during early phases of primary sublethal infection, while their congenic C57BL/10N [Bcg(s)] counterparts could be classified as resistant to F. tularensis LVS infection according to the 2-log-lower bacterial CFU within the tissue as long as 5 days after infection. Different phenotypes of Bcg congenic mice were associated with differential expression of the cytokines tumor necrosis factor alpha, interleukin-10, and gamma interferon and production of reactive oxygen intermediates. These results strongly suggest that the Bcg locus, which is close or identical to the Nramp1 gene, controls natural resistance to infection by F. tularensis and that its effect is the opposite of that observed for other Bcg-controlled pathogens.  (+info)

The pathology of untreated and antibiotic-treated experimental tularaemia in monkeys. (7/568)

Grivet monkeys were infected intranasally with the virulent Schu-S4 strain of F. tularensis. One group of animals remained untreated and two other groups received a 7-day course of kanamycin therapy starting on either the third or fourth day after infection. Untreated monkeys developed pyrexia and mucopurulent oculonasal discharge and died 5--7 days after infection. All had pyogranulomatous lesions in the liver, spleen, respiratory tract and lymph nodes. Electron microscopy of liver and spleen showed phagocytosis of F. tularensis organisms by macrophages and polymorphonuclear leucocytes, but many bacteria survived phagocytosis and were released on destruction of the cells. Kanamycin therapy enabled most monkeys to survive the disease, but it did not prevent the development of persistent lesions in all animals. Caseous nodules were larger and more widespread in the organs of monkeys in which treatment was delayed until the fourth day of infection.  (+info)

Changes in whole blood and serum components of grivet monkeys with experimental respiratory Francisella tularensis infection. (8/568)

Grivet monkeys infected with virulent Francisella tularensis Strain Schu S4 showed significant early changes in serum levels of trace metals, triglycerides and activities of alkaline phosphatase, lactate dehydrogenase and alpha-hydroxybutyrate dehydrogenase. Free amino acid levels decreased slightly and there was a marked increase in the phenylalanine: tyrosine ratio. Serum lysozyme activity and seromucoid levels also increased. Kanamycin therapy produced remission of overt signs but the changes in blood constituents were less readily affected. Immunization with the live vaccine strain of F. tularensis induced transient responses similar to those resulting from Schut S4 infection. Immunized monkeys subsequently challenged with the virulent Schu S4 strain showed no clinical signs or marked changes in blood constituents.  (+info)

Tularemia is a bacterial disease caused by the gram-negative, facultatively intracellular bacterium Francisella tularensis. It is a zoonotic disease, meaning it primarily affects animals, but can also be transmitted to humans through various modes of exposure such as contact with infected animals or their tissues, ingestion of contaminated food or water, inhalation of infective aerosols, or bites from infected arthropods.

Humans typically develop symptoms within 3-5 days after exposure, which can vary depending on the route of infection and the specific Francisella tularensis subspecies involved. Common manifestations include fever, chills, headache, muscle aches, and fatigue. Depending on the type of tularemia, other symptoms may include skin ulcers, swollen lymph nodes, cough, chest pain, or diarrhea.

Tularemia is often classified into different clinical forms based on the route of infection and the initial site of multiplication:

1. Ulceroglandular tularemia: This form results from the bite of an infected arthropod (e.g., tick or deer fly) or contact with contaminated animal tissues, leading to a skin ulcer at the site of infection and swollen lymph nodes.
2. Glandular tularemia: Similar to ulceroglandular tularemia but without an obvious skin ulcer.
3. Oculoglandular tularemia: This form occurs when the bacteria come into contact with the eye, causing a painful inflammation of the eyelid and conjunctiva, along with swollen lymph nodes.
4. Oropharyngeal tularemia: Ingestion of contaminated food or water can lead to this form, characterized by sore throat, mouth ulcers, and swollen lymph nodes in the neck.
5. Pneumonic tularemia: This form results from inhalation of infective aerosols and is often associated with severe respiratory symptoms such as cough, chest pain, and pneumonia.
6. Typhoidal tularemia: A rare and severe form characterized by fever, rash, and systemic infection without any localizing signs or symptoms.

Tularemia is a serious bacterial infection that can be transmitted to humans through various routes, including insect bites, contact with contaminated animal tissues, ingestion of contaminated food or water, and inhalation of infective aerosols. Prompt diagnosis and appropriate antibiotic treatment are crucial for successful management of this potentially life-threatening disease.

"Francisella tularensis" is a gram-negative, aerobic, coccobacillus bacterium that is the etiological agent of tularemia. It is highly infectious and can be transmitted to humans through various routes such as contact with infected animals, ingestion of contaminated food or water, inhalation of contaminated aerosols, or bites from infected arthropods. The bacterium can cause a range of clinical manifestations depending on the route of infection and includes ulceroglandular, oculoglandular, oropharyngeal, pneumonic, and typhoidal tularemia. "Francisella tularensis" is considered a potential bioterrorism agent due to its high infectivity and potential for causing severe illness and death.

I believe there might be some confusion in your question. "Hares" is a common name used to refer to certain types of fast-running mammals that belong to the family Leporidae and the genus Lepus. They are known for their long ears and powerful hind legs, which allow them to move quickly through open fields.

However, if you are referring to a medical term, it is possible that you may have misspelled the word. If you meant "hairs" instead of "hares," then I can provide you with a definition related to medicine.

In medical terms, hairs refer to the keratinous filaments that grow from follicles in the skin of mammals, including humans. They serve various functions, such as sensory perception, thermoregulation, and protection. Hair growth, structure, and distribution can also provide valuable diagnostic information for certain medical conditions.

"Francisella" is a genus of gram-negative, aerobic bacteria that are highly fastidious and require specialized media for growth. The most well-known species is "Francisella tularensis," which is the causative agent of tularemia, a zoonotic disease that can be transmitted to humans through various routes, including insect bites, contaminated water or food, and direct contact with infected animals.

"Francisella tularensis" is highly infectious and can cause severe illness, even at low doses. There are two main subspecies of "F. tularensis": "tularensis," which is found mainly in North America and causes more severe disease, and "holarctica," which is found throughout the Northern Hemisphere and generally causes less severe illness.

Other species in the genus "Francisella" include "F. philomiragia," which can cause respiratory and wound infections in humans, and "F. novicida," which is highly virulent in mice but rarely causes disease in humans.

Bacterial vaccines are types of vaccines that are created using bacteria or parts of bacteria as the immunogen, which is the substance that triggers an immune response in the body. The purpose of a bacterial vaccine is to stimulate the immune system to develop protection against specific bacterial infections.

There are several types of bacterial vaccines, including:

1. Inactivated or killed whole-cell vaccines: These vaccines contain entire bacteria that have been killed or inactivated through various methods, such as heat or chemicals. The bacteria can no longer cause disease, but they still retain the ability to stimulate an immune response.
2. Subunit, protein, or polysaccharide vaccines: These vaccines use specific components of the bacterium, such as proteins or polysaccharides, that are known to trigger an immune response. By using only these components, the vaccine can avoid using the entire bacterium, which may reduce the risk of adverse reactions.
3. Live attenuated vaccines: These vaccines contain live bacteria that have been weakened or attenuated so that they cannot cause disease but still retain the ability to stimulate an immune response. This type of vaccine can provide long-lasting immunity, but it may not be suitable for people with weakened immune systems.

Bacterial vaccines are essential tools in preventing and controlling bacterial infections, reducing the burden of diseases such as tuberculosis, pneumococcal disease, meningococcal disease, and Haemophilus influenzae type b (Hib) disease. They work by exposing the immune system to a harmless form of the bacteria or its components, which triggers the production of antibodies and memory cells that can recognize and fight off future infections with that same bacterium.

It's important to note that while vaccines are generally safe and effective, they may cause mild side effects such as pain, redness, or swelling at the injection site, fever, or fatigue. Serious side effects are rare but can occur, so it's essential to consult with a healthcare provider before receiving any vaccine.

Pharyngeal diseases refer to conditions that affect the pharynx, which is the part of the throat that lies behind the nasal cavity and mouth, and above the esophagus and larynx. The pharynx plays a crucial role in swallowing, speaking, and breathing. Pharyngeal diseases can cause symptoms such as sore throat, difficulty swallowing, pain during swallowing, swollen lymph nodes, and earaches.

Some common pharyngeal diseases include:

1. Pharyngitis: Inflammation of the pharynx, often caused by a viral or bacterial infection.
2. Tonsillitis: Inflammation of the tonsils, which are two masses of lymphoid tissue located on either side of the back of the throat.
3. Epiglottitis: Inflammation of the epiglottis, a flap of cartilage that covers the windpipe during swallowing to prevent food and liquids from entering the lungs.
4. Abscesses: A collection of pus in the pharynx caused by a bacterial infection.
5. Cancer: Malignant tumors that can develop in the pharynx, often caused by smoking or heavy alcohol use.
6. Dysphagia: Difficulty swallowing due to nerve damage, muscle weakness, or structural abnormalities in the pharynx.
7. Stridor: Noisy breathing caused by a narrowed or obstructed airway in the pharynx.

Treatment for pharyngeal diseases depends on the underlying cause and may include antibiotics, pain relievers, surgery, or radiation therapy.

I apologize, but "Bulgaria" is not a medical term or condition. It is a country located in southeastern Europe, known for its rich history, diverse culture, and natural beauty. If you have any questions related to the field of medicine or health, I would be happy to try to help answer them for you.

Lymphatic diseases refer to a group of conditions that affect the lymphatic system, which is an important part of the immune and circulatory systems. The lymphatic system consists of a network of vessels, organs, and tissues that help to transport lymph fluid throughout the body, fight infection, and remove waste products.

Lymphatic diseases can be caused by various factors, including genetics, infections, cancer, and autoimmune disorders. Some common types of lymphatic diseases include:

1. Lymphedema: A condition that causes swelling in the arms or legs due to a blockage or damage in the lymphatic vessels.
2. Lymphoma: A type of cancer that affects the lymphatic system, including Hodgkin's and non-Hodgkin's lymphoma.
3. Infections: Certain bacterial and viral infections can affect the lymphatic system, such as tuberculosis, cat-scratch disease, and HIV/AIDS.
4. Autoimmune disorders: Conditions such as rheumatoid arthritis, lupus, and scleroderma can cause inflammation and damage to the lymphatic system.
5. Congenital abnormalities: Some people are born with abnormalities in their lymphatic system, such as malformations or missing lymph nodes.

Symptoms of lymphatic diseases may vary depending on the specific condition and its severity. Treatment options may include medication, physical therapy, surgery, or radiation therapy. It is important to seek medical attention if you experience symptoms of a lymphatic disease, as early diagnosis and treatment can improve outcomes.

Attenuated vaccines consist of live microorganisms that have been weakened (attenuated) through various laboratory processes so they do not cause disease in the majority of recipients but still stimulate an immune response. The purpose of attenuation is to reduce the virulence or replication capacity of the pathogen while keeping it alive, allowing it to retain its antigenic properties and induce a strong and protective immune response.

Examples of attenuated vaccines include:

1. Sabin oral poliovirus vaccine (OPV): This vaccine uses live but weakened polioviruses to protect against all three strains of the disease-causing poliovirus. The weakened viruses replicate in the intestine and induce an immune response, which provides both humoral (antibody) and cell-mediated immunity.
2. Measles, mumps, and rubella (MMR) vaccine: This combination vaccine contains live attenuated measles, mumps, and rubella viruses. It is given to protect against these three diseases and prevent their spread in the population.
3. Varicella (chickenpox) vaccine: This vaccine uses a weakened form of the varicella-zoster virus, which causes chickenpox. By introducing this attenuated virus into the body, it stimulates an immune response that protects against future infection with the wild-type virus.
4. Yellow fever vaccine: This live attenuated vaccine is used to prevent yellow fever, a viral disease transmitted by mosquitoes in tropical and subtropical regions of Africa and South America. The vaccine contains a weakened form of the yellow fever virus that cannot cause the disease but still induces an immune response.
5. Bacillus Calmette-Guérin (BCG) vaccine: This live attenuated vaccine is used to protect against tuberculosis (TB). It contains a weakened strain of Mycobacterium bovis, which does not cause TB in humans but stimulates an immune response that provides some protection against the disease.

Attenuated vaccines are generally effective at inducing long-lasting immunity and can provide robust protection against targeted diseases. However, they may pose a risk for individuals with weakened immune systems, as the attenuated viruses or bacteria could potentially cause illness in these individuals. Therefore, it is essential to consider an individual's health status before administering live attenuated vaccines.

I'm sorry for any confusion, but "Turkey" is not a medical term. It is a common name for the country located in Eastern Europe and Western Asia, as well as a type of large bird native to North America that is often eaten as a holiday meal. If you have any questions about medical terminology or health-related topics, I'd be happy to try and help answer them!

I'm sorry for any confusion, but "Wyoming" is not a medical term or condition. It is the name of a state, the 44th state to be admitted into the United States of America. Wyoming is located in the western part of the country and is known for its natural beauty, including Yellowstone National Park, which is partially located within its borders. If you have any questions about medical terms or conditions, I'd be happy to try to help answer those for you!

Lagomorpha is an order of mammals that includes rabbits, hares, and pikas. They are herbivores with large incisors in the front of their mouths and a second pair of smaller incisors behind them. Lagomorpha is distinguished from other orders by its unique dental characteristics and the presence of two pairs of upper incisors. These animals are known for their high reproductive rates and are found worldwide, except for Antarctica and some islands.

I apologize for any confusion, but "Mephitidae" is not a medical term. It is a taxonomic category in biology, specifically referring to a family of mammals that includes skunks and stink badgers. These animals are known for their ability to produce and spray foul-smelling liquids as a defense mechanism.

A disease outbreak is defined as the occurrence of cases of a disease in excess of what would normally be expected in a given time and place. It may affect a small and localized group or a large number of people spread over a wide area, even internationally. An outbreak may be caused by a new agent, a change in the agent's virulence or host susceptibility, or an increase in the size or density of the host population.

Outbreaks can have significant public health and economic impacts, and require prompt investigation and control measures to prevent further spread of the disease. The investigation typically involves identifying the source of the outbreak, determining the mode of transmission, and implementing measures to interrupt the chain of infection. This may include vaccination, isolation or quarantine, and education of the public about the risks and prevention strategies.

Examples of disease outbreaks include foodborne illnesses linked to contaminated food or water, respiratory infections spread through coughing and sneezing, and mosquito-borne diseases such as Zika virus and West Nile virus. Outbreaks can also occur in healthcare settings, such as hospitals and nursing homes, where vulnerable populations may be at increased risk of infection.

Agglutination tests are laboratory diagnostic procedures used to detect the presence of antibodies or antigens in a sample, such as blood or serum. These tests work by observing the clumping (agglutination) of particles, like red blood cells or bacteriophages, coated with specific antigens or antibodies when mixed with a patient's sample.

In an agglutination test, the sample is typically combined with a reagent containing known antigens or antibodies on the surface of particles, such as latex beads, red blood cells, or bacteriophages. If the sample contains the corresponding antibodies or antigens, they will bind to the particles, forming visible clumps or agglutinates. The presence and strength of agglutination are then assessed visually or with automated equipment to determine the presence and quantity of the target antigen or antibody in the sample.

Agglutination tests are widely used in medical diagnostics for various applications, including:

1. Bacterial and viral infections: To identify specific bacterial or viral antigens in a patient's sample, such as group A Streptococcus, Legionella pneumophila, or HIV.
2. Blood typing: To determine the ABO blood group and Rh type of a donor or recipient before a blood transfusion or organ transplantation.
3. Autoimmune diseases: To detect autoantibodies in patients with suspected autoimmune disorders, such as rheumatoid arthritis, systemic lupus erythematosus, or Hashimoto's thyroiditis.
4. Allergies: To identify specific IgE antibodies in a patient's sample to determine allergic reactions to various substances, such as pollen, food, or venom.
5. Drug monitoring: To detect and quantify the presence of drug-induced antibodies, such as those developed in response to penicillin or hydralazine therapy.

Agglutination tests are simple, rapid, and cost-effective diagnostic tools that provide valuable information for clinical decision-making and patient management. However, they may have limitations, including potential cross-reactivity with other antigens, false-positive results due to rheumatoid factors or heterophile antibodies, and false-negative results due to the prozone effect or insufficient sensitivity. Therefore, it is essential to interpret agglutination test results in conjunction with clinical findings and other laboratory data.

Zoonoses are infectious diseases that can be transmitted from animals to humans. They are caused by pathogens such as viruses, bacteria, parasites, or fungi that naturally infect non-human animals and can sometimes infect and cause disease in humans through various transmission routes like direct contact with infected animals, consumption of contaminated food or water, or vectors like insects. Some well-known zoonotic diseases include rabies, Lyme disease, salmonellosis, and COVID-19 (which is believed to have originated from bats). Public health officials work to prevent and control zoonoses through various measures such as surveillance, education, vaccination, and management of animal populations.

The oropharynx is the part of the throat (pharynx) that is located immediately behind the mouth and includes the back one-third of the tongue, the soft palate, the side and back walls of the throat, and the tonsils. It serves as a passageway for both food and air, and is also an important area for the immune system due to the presence of tonsils.

Otorhinolaryngologic diseases, also known as ear, nose, and throat (ENT) diseases, refer to a group of medical conditions that affect the ears, nose, and/or throat. These specialized areas are closely related both anatomically and functionally, and disorders in one area can often have impacts on the others.

Here are some examples of otorhinolaryngologic diseases categorized by the affected area:

1. Otologic diseases - affecting the ear:
* Otitis media (ear infection)
* Otitis externa (swimmer's ear)
* Tinnitus (ringing in the ears)
* Hearing loss
* Meniere's disease (inner ear disorder causing vertigo, tinnitus, and hearing loss)
* Acoustic neuroma (noncancerous tumor on the vestibular nerve)
2. Rhinologic diseases - affecting the nose:
* Allergic rhinitis (hay fever)
* Non-allergic rhinitis
* Sinusitis (sinus infection)
* Deviated septum
* Nasal polyps
* Epistaxis (nosebleed)
3. Laryngologic diseases - affecting the throat and voice box:
* Laryngitis (inflammation of the larynx, causing hoarseness or voice loss)
* Vocal cord nodules or polyps
* Reflux laryngitis (acid reflux irritating the throat)
* Subglottic stenosis (narrowing of the airway below the vocal cords)
* Laryngeal cancer
4. Common otorhinolaryngologic diseases:
* Tonsillitis (inflammation of the tonsils, often causing sore throat and difficulty swallowing)
* Adenoiditis (inflammation of the adenoids, commonly seen in children)
* Obstructive sleep apnea (OSA, a disorder characterized by pauses in breathing during sleep)
* Pharyngitis (inflammation of the pharynx or throat)

Otorhinolaryngologists, also known as ENT specialists, diagnose and treat these conditions. They may use various methods such as physical examination, imaging studies, endoscopy, and laboratory tests to determine the best course of treatment for each individual patient.

Bacterial antibodies are a type of antibodies produced by the immune system in response to an infection caused by bacteria. These antibodies are proteins that recognize and bind to specific antigens on the surface of the bacterial cells, marking them for destruction by other immune cells. Bacterial antibodies can be classified into several types based on their structure and function, including IgG, IgM, IgA, and IgE. They play a crucial role in the body's defense against bacterial infections and provide immunity to future infections with the same bacteria.

Lymphadenitis is a medical term that refers to the inflammation of one or more lymph nodes, which are small, bean-shaped glands that are part of the body's immune system. Lymph nodes contain white blood cells called lymphocytes, which help fight infection and disease.

Lymphadenitis can occur as a result of an infection in the area near the affected lymph node or as a result of a systemic infection that has spread through the bloodstream. The inflammation causes the lymph node to become swollen, tender, and sometimes painful to the touch.

The symptoms of lymphadenitis may include fever, fatigue, and redness or warmth in the area around the affected lymph node. In some cases, the overlying skin may also appear red and inflamed. Lymphadenitis can occur in any part of the body where there are lymph nodes, including the neck, armpits, groin, and abdomen.

The underlying cause of lymphadenitis must be diagnosed and treated promptly to prevent complications such as the spread of infection or the formation of an abscess. Treatment may include antibiotics, pain relievers, and warm compresses to help reduce swelling and discomfort.

Dermacentor is a genus of ticks that includes several species known to transmit diseases to humans and animals. Some of the notable species in this genus are:

1. Dermacentor andersoni (Rocky Mountain wood tick): This species is widely distributed across western North America and can transmit Rocky Mountain spotted fever, Colorado tick fever, and tularemia.
2. Dermacentor variabilis (American dog tick): Found throughout the United States, this tick can transmit Rocky Mountain spotted fever, tularemia, and human ehrlichiosis.
3. Dermacentor reticulatus (Ornate cow tick or Marsh tick): This species is distributed in Europe and parts of Asia and can transmit diseases like tick-borne encephalitis, louping ill, and babesiosis.
4. Dermacentor marginatus (Marginated tick): Found primarily in Europe, this tick transmits various pathogens causing diseases such as Crimean-Congo hemorrhagic fever, tick-borne encephalitis, and rickettsialpox.
5. Dermacentor nitens (Brazilian pampas tick): This species is native to South America and can transmit Rickettsia rickettsii, the bacterium that causes Rocky Mountain spotted fever.

Dermacentor ticks are known for their hard, shield-like structures called scutums on their backs and their long mouthparts called hypostomes, which they use to feed on the blood of their hosts. They typically prefer large mammals as hosts but will also feed on humans and other animals if necessary.

Bioterrorism is the intentional use of microorganisms or toxins derived from living organisms to cause disease, death, or disruption in noncombatant populations. Biological agents can be spread through the air, water, or food and may take hours to days to cause illness, depending on the agent and route of exposure. Examples of biological agents that could be used as weapons include anthrax, smallpox, plague, botulism toxin, and viruses that cause hemorrhagic fevers, such as Ebola. Bioterrorism is a form of terrorism and is considered a public health emergency because it has the potential to cause widespread illness and death, as well as social disruption and economic loss.

The medical definition of bioterrorism focuses on the use of biological agents as weapons and the public health response to such attacks. It is important to note that the majority of incidents involving the intentional release of biological agents have been limited in scope and have not resulted in widespread illness or death. However, the potential for large-scale harm makes bioterrorism a significant concern for public health officials and emergency responders.

Preparation and response to bioterrorism involve a multidisciplinary approach that includes medical professionals, public health officials, law enforcement agencies, and government organizations at the local, state, and federal levels. Preparedness efforts include developing plans and procedures for responding to a bioterrorism event, training healthcare providers and first responders in the recognition and management of biological agents, and stockpiling vaccines, medications, and other resources that may be needed during a response.

In summary, bioterrorism is the intentional use of biological agents as weapons to cause illness, death, or disruption in noncombatant populations. It is considered a public health emergency due to its potential for widespread harm and requires a multidisciplinary approach to preparedness and response.

I'm sorry for any confusion, but "Yugoslavia" is not a medical term. It refers to a country in southeastern Europe that existed from 1929 to 2006. The country was originally named the Kingdom of Serbs, Croats, and Slovenes, but it was renamed Yugoslavia in 1929. After World War II, it became a socialist federal republic. The country dissolved in the 1990s amidst political turmoil and ethnic conflict, leading to the formation of several independent countries, including Bosnia and Herzegovina, Croatia, Kosovo, Montenegro, North Macedonia, Serbia, and Slovenia. I hope this clarifies things! If you have any other questions, please let me know.

A medical definition of "ticks" would be:

Ticks are small, blood-sucking parasites that belong to the arachnid family, which also includes spiders. They have eight legs and can vary in size from as small as a pinhead to about the size of a marble when fully engorged with blood. Ticks attach themselves to the skin of their hosts (which can include humans, dogs, cats, and wild animals) by inserting their mouthparts into the host's flesh.

Ticks can transmit a variety of diseases, including Lyme disease, Rocky Mountain spotted fever, anaplasmosis, ehrlichiosis, and babesiosis. It is important to remove ticks promptly and properly to reduce the risk of infection. To remove a tick, use fine-tipped tweezers to grasp the tick as close to the skin's surface as possible and pull upward with steady, even pressure. Do not twist or jerk the tick, as this can cause the mouthparts to break off and remain in the skin. After removing the tick, clean the area with soap and water and disinfect the tweezers.

Preventing tick bites is an important part of protecting against tick-borne diseases. This can be done by wearing protective clothing (such as long sleeves and pants), using insect repellent containing DEET or permethrin, avoiding wooded and brushy areas with high grass, and checking for ticks after being outdoors.

"Bites and stings" is a general term used to describe injuries resulting from the teeth or venomous secretions of animals. These can include:

1. Insect bites: The bite marks are usually small, punctate, and may be accompanied by symptoms such as redness, swelling, itching, and pain. Examples include mosquito, flea, bedbug, and tick bites.

2. Spider bites: Some spiders possess venomous fangs that can cause localized pain, redness, and swelling. In severe cases, systemic symptoms like muscle cramps, nausea, vomiting, and difficulty breathing may occur. The black widow and brown recluse spiders are notorious for their venomous bites.

3. Snake bites: Venomous snakes deliver toxic saliva through their fangs, which can lead to local tissue damage, swelling, pain, and potentially life-threatening systemic effects such as paralysis, bleeding disorders, and respiratory failure.

4. Mammal bites: Animal bites from mammals like dogs, cats, and wild animals can cause puncture wounds, lacerations, and crush injuries. They may also transmit infectious diseases, such as rabies.

5. Marine animal stings: Stings from jellyfish, sea urchins, stingrays, and other marine creatures can result in localized pain, redness, swelling, and systemic symptoms like difficulty breathing, muscle cramps, and altered heart rhythms. Some marine animals' venoms can cause severe allergic reactions or even death.

Treatment for bites and stings varies depending on the type and severity of the injury. It may include wound care, pain management, antibiotics to prevent infection, and in some cases, antivenom therapy to counteract the effects of venom. Seeking immediate medical attention is crucial in severe cases or when systemic symptoms are present.

Tonsillitis is a medical condition characterized by inflammation and infection of the tonsils, which are two masses of lymphoid tissue located on either side of the back of the throat. The tonsils serve as a defense mechanism against inhaled or ingested pathogens; however, they can become infected themselves, leading to tonsillitis.

The inflammation of the tonsils is often accompanied by symptoms such as sore throat, difficulty swallowing, fever, swollen and tender lymph nodes in the neck, cough, headache, and fatigue. In severe or recurrent cases, a tonsillectomy (surgical removal of the tonsils) may be recommended to alleviate symptoms and prevent complications.

Tonsillitis can be caused by both viral and bacterial infections, with group A streptococcus being one of the most common bacterial causes. It is typically diagnosed based on a physical examination and medical history, and sometimes further confirmed through laboratory tests such as a throat swab or rapid strep test. Treatment may include antibiotics for bacterial tonsillitis, pain relievers, and rest to aid in recovery.

"Rodentia" is not a medical term, but a taxonomic category in biology. It refers to the largest order of mammals, comprising over 40% of all mammal species. Commonly known as rodents, this group includes mice, rats, hamsters, gerbils, guinea pigs, squirrels, prairie dogs, capybaras, beavers, and many others.

While "Rodentia" itself is not a medical term, certain conditions or issues related to rodents can have medical implications. For instance, rodents are known to carry and transmit various diseases that can affect humans, such as hantavirus, leptospirosis, salmonellosis, and lymphocytic choriomeningitis (LCMV). Therefore, understanding the biology and behavior of rodents is important in the context of public health and preventive medicine.

Medical Definition:

Lethal Dose 50 (LD50) is a standard measurement in toxicology that refers to the estimated amount or dose of a substance, which if ingested, injected, inhaled, or absorbed through the skin by either human or animal, would cause death in 50% of the test population. It is expressed as the mass of a substance per unit of body weight (mg/kg, μg/kg, etc.). LD50 values are often used to compare the toxicity of different substances and help determine safe dosage levels.

I'm sorry for any confusion, but "Missouri" is not a medical term or concept. It is a geographical location, being the name of a state located in the central United States. If you have any questions related to medical terminology or concepts, I would be happy to help with those!

I could not find a medical definition specifically for "camping," but I can provide you with some general information about camping as it relates to recreation and outdoor activities, which may be helpful.

Camping is an activity where individuals or groups go outdoors to spend time in natural surroundings, usually in tents, recreational vehicles, or cabins. It often involves staying overnight in a designated campsite, although some people may engage in backcountry camping, which requires hiking and setting up camp in more remote areas.

Camping can provide various physical and mental health benefits, such as:

1. Exposure to nature: Being outdoors in natural surroundings can help reduce stress, improve mood, and boost overall well-being.
2. Physical activity: Camping often involves hiking, swimming, or other outdoor activities that can improve cardiovascular fitness, strength, and flexibility.
3. Social connection: Camping with friends or family can foster social bonds and create shared memories.
4. Skill development: Camping requires learning various skills, such as setting up a tent, building a fire, and cooking outdoors, which can help build confidence and self-reliance.
5. Disconnection from technology: Camping often involves limited access to electronic devices, providing an opportunity to disconnect from the digital world and recharge mentally.

It is essential to follow safety guidelines when camping, such as practicing proper food storage to avoid attracting wildlife, using insect repellent to prevent bug bites, and being aware of potential hazards like poisonous plants or wild animals. Additionally, it's crucial to leave no trace and respect the natural environment by properly disposing of waste and minimizing impact on the surroundings.

See Tularemia For Clinicians for detailed treatment information.. Tularemia prophylaxis is recommended in cases of laboratory ... Tularemia treatment regimen. Age Category. Drug. Dosage. Maximum. Duration (Days). Adults. Gentamicin*. 5 mg/kg IM or IV daily ... Tularemia has been reported in all states except Hawaii, but it is most common in the south-central United States, the Great ... Tularemia is caused by the highly infectious F. tularensis bacteria. It is spread through exposure to infected arthropods ( ...
"WHO Guidelines on Tularemia" Published 2007 "Tularemia , CDC". www.cdc.gov. Retrieved 2017-03-12. Kinkead, LC; Allen, LA ( ... "Diagnosis and Treatment Tularemia". CDC. October 2015. Retrieved 8 November 2017. "Prevention Tularemia". www.cdc.gov. October ... "Transmission Tularemia". CDC. October 2015. Retrieved 8 November 2017. "Clinicians Tularemia". www.cdc.gov. September 2016. ... Jellison WL, Owen C, Bell JF, Kohls GM (1961). "Tularemia and animal populations". Wildl Dis. 17: 1-22. "Tularemia Transmission ...
... is a plague-like disease caused by the bacterium Francisella tularensis . U.S. weapons stores of tularemia bacteria ... If left untreated, tularemia can persist for weeks, even months, and can be fatal. The severe form of tularemia can kill up to ... Dennis, D. T. Tularemia. In: Wallace, R. B. ed. Maxcy-Rosenau-Last Public Health and Preventive Medicine, 14th edition. ... Chin, J. Tularemia. In Control of Communicable Diseases Manual. Washington, DC: American Public Health Association, 2000. ...
Tularemia blood test checks for infection caused by bacteria called Francisella tularensis (F tularensis). The bacteria causes ... Tularemia blood test checks for infection caused by bacteria called Francisella tularensis (F tularensis). The bacteria causes ... Tularemia blood test checks for infection caused by bacteria called Francisella tularensis (F tularensis). The bacteria causes ... Francisella tularensis (tularemia). In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennetts Principles and ...
Tularemia * Infection Control (from Abstract of "Consensus Statement: Tularemia as a Biological Weapon: Medical and Public ...
Tularemia is an acute, febrile, granulomatous, infectious zoonosis caused by Francisella tularensis, an aerobic, gram-negative ... Types of tularemia. Some authorities classify tularemia into 2 groups, which include the far more common ulceroglandular form ( ... Pneumonia also occurs in 10-15% of patients with ulceroglandular tularemia and in 50% of those with typhoidal tularemia. The ... encoded search term (Tularemia) and Tularemia What to Read Next on Medscape ...
Information about tularemia, or rabbit fever, a disease primarily of rabbits but can also be found in rodents and transmitted ... Tularemia Information about tularemia, or rabbit fever, a disease primarily of rabbits but can also be found in rodents and ... Tularemia. Information about tularemia, or rabbit fever, a disease primarily of rabbits but can also be found in rodents and ... Tularemia. Tularemia is a naturally-occurring, tick transmitted disease of rabbits and rodents caused by the bacterium ...
Serology for tularemia is a blood test that checks for infection caused by bacteria called Francisella tularensis which causes ... Tularemia agglutinins - serum. In: Chernecky CC, Berger BJ, eds. Laboratory Tests and Diagnostic Procedures. 6th ed. St Louis, ... Tularemia blood test checks for infection caused by bacteria called Francisella tularensis (F tularensis). The bacteria causes ... Francisella tularensis (tularemia). In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennetts Principles and ...
CDC Tularemia Frequently Asked Questions. CDC Information on Tularemia Symptoms. CDC Information on Tularemia Treatment. CDC ... Tularemia is very rare in San Diego.. The Vector Control Program routinely collects, identifies, and tests ticks for tularemia ... Tularemia, also known as Rabbit Fever, is caused by the bacteria Francisella tularensis, found in wild rodents and rabbits. It ... Tularemia has been reported in many areas of the country. It is most frequently seen in the northern areas of California. ...
Tularemia: Other Resources * Communicating in the First Hours: Tularemia The First Hours project provides messages and other ... MMWR: Tularemia-United States, 1990-2000. MMWR 2002 Mar 8;51(9):182-184.. pdf icon(368 KB/24 pages) ... Abstract of "Consensus Statement: Tularemia as a Biological Weapon: Medical and Public Health Management". Concise, bulleted ...
Q. What is tularemia? A. Tularemia, also known as "rabbit fever," is a disease caused by the bacterium Francisella tularensis. ... Q. Does tularemia occur naturally in the United States? A. Yes. Tularemia is a widespread disease in animals. About 200 human ... Q. How is tularemia diagnosed? A. When a person has symptoms that appear related to tularemia, the healthcare worker collects ... Q. What should someone do if he or she suspects exposure to tularemia bacteria? A. If you suspect you were exposed to tularemia ...
Learn about the veterinary topic of Tularemia in Cats. Find specific details on this topic and related topics from the Merck ... Also see professional content regarding tularemia Tularemia in Animals Tularemia is a bacterial septicemia that infects >250 ... Tularemia in Cats By Janet E. Foley , DVM, PhD, Department of Medicine and Epidemiology, School of Veterinary Medicine, ... Tularemia is a bacterial disease that affects people and many species of wild and domestic animals. It is caused by toxins in ...
Tularemia, also called rabbit fever, is, unlike anthrax or smallpox, the bioweapon you are least likely to know about. But it ... Tularemia: Rabbit Fever, The Bioweapon You Probably Never Heard Of. By News Staff , February 17th 2014 03:34 PM , Print , E- ... Tularemia, also called "rabbit fever", is, unlike anthrax or smallpox, the bioweapon you are least likely to know about. ... of environmental persistence and pathogenesis might lead to better diagnostics and/or novel countermeasures to combat tularemia ...
MAXIMUM 150 WORDS: Remember: front load your paragraphs! This content should include a strong opening sentence describing the health topic in the Eastern Mediterranean (include key words "Eastern Mediterranean" and health topic name for search engine optimization). You should focus on the issue as it relates to the Region and the magnitude of problem in the region, as well as a brief mention of current situation/problem.. ...
Tularemia is a bacterial septicemia that infects >250 species of wild and domestic mammals, birds, reptiles, fish, and people. ...
Information about Tularemia in Alaska such as animals affected, causes, signs and protective measures. ... Tularemia Fact Sheet for Pet Owners (PDF 42 kB) *Contact of an infected pets saliva or an infected hares fluids into a cut, ... Tularemia. A red squirrel with the common squirrel or vole tick, Ixodes angustus, which is the most common native tick in ... Tularemia is caused by a bacterium known as Francisella tularensis.. *There are two major cycles of this disease. The first ...
The inflammasome that attacks the tularemia bacterium is triggered by the sensor protein AIM2 that recognizes the tularemia DNA ... Tularemia is a highly infectious disease that kills more than 30 percent of those infected, if left untreated. It can be ... Jude Department of Immunology, found key receptors responsible for sensing DNA in cells infected by the tularemia-causing ... Studies with mice demonstrated the necessary role IRF1 plays in galvanizing the immune system to battle tularemia. Mice lacking ...
Some Epidemiological Observations on Tularemia in California 1927-1951 published on May 1953 by The American Society of ... The incidence of tularemia in the decade 1933-1942 was 16 cases a year but it has declined during the last ten years to an ... The incidence of tularemia in California does not warrant its consideration as a major public health problem. An educational ... A study of 266 authenticated cases of tularemia in California occurring from 1927-1951 showed that 81 per cent were contracted ...
Francisella tularensis is a re-emerging organism causing more significant outbreaks of tularemia and fear of bioterrorism. It ... We encountered a case of pulmonary tularemia with a unique presentation of severe headache and fever. ... An Uncommon Presentation of Pulmonary Tularemia: A Case Report and Literature Review. ... can be challenging to recognize tularemia due to its variable presentation, especially in low-incidence areas. Physicians must ...
Oculoglandular form of tularemia is very infrequent in our environment. In Spain some studies show an incidence of this form ... Tularemia is a zoonotic disease caused by Francisella tularensis, a Gram-negative facultative intracellular coccobacillus1 with ... We have previously published the first case of ulceroglandular tularemia in a non-endemic area (Asturias, Spain).5 Here, we ... The gold standard for the diagnosis of tularemia is the isolation of the causative agent by culture, however, this is difficult ...
... a meeting organized by Tularemia International Society. From the International Congress Calendar, a service of the UIA. ... International Conference on Tularemia #10 Date & Location(s):. 25. Sep 2023 - 28. Sep 2023. Grenoble, France. Organizer(s):. ... Tularemia International Society (TULISOC). View Organization Profile Contact Information:. Physical Address: Available with ...
Fields of Study , epidemiology , vector-borne diseases , arthropod-borne diseases , tick-borne diseases , tularemia ...
Inguinal Ulceroglandular Tularemia Caused by Francisella tularensis Subspecies holarctica, Canada Cite CITE. Title : Inguinal ... Tularemia is a zoonotic disease caused by the gram-negative coccobacillus Francisella tularensis, a Biosafety Level 3 pathogen ... Animals Arvicolinae Communicable Diseases, Emerging Francisella Tularensis Hares Humans Risk Factors Tularemia Zoonoses ... In November 2012, a group of 7 persons who participated in a hare hunt in North Rhine-Westphalia, Germany, acquired tularemia. ...
Tularemia has been diagnosed in five dogs and cats in Sioux Falls, South Dakota. At least one of the pets has died. Tularemia, ... Tularemia has been diagnosed in five dogs and cats in Sioux Falls, South Dakota. At least one of the pets has died. Tularemia, ... You can reduce the risk of your pet being exposed to tularemia by:. *Keeping pets indoors as much as possible. Cats should stay ... Transmission of tularemia from infected pets to humans is also a concern. This has been reported in numerous instances, most ...
... resources and related links for tularemia,&nbsp;a rare disease caused by the bacteria Francella tularensis. ... Tularemia - Centers for Disease Control and Prevention * Appendix 1: Case Definitions and Disease Specific Information: ... Tularemia is a rare disease caused by the bacteria Francella tularensis. Wild animals, especially rabbits and some domestic ... While tularemia infections may result in a number of different clinical presentations, the most frequent symptoms are an ulcer ...
... Petra C.F. Oyston, Anders Sjöstedt, Richard W. ... Tularaemia: bioterrorism defence renews interest in Francisella tularensis. , Nature Reviews Microbiology, December 2004, ...
"Tularemia in a Park, Philadelphia, Pennsylvania" 14, no. 9 (2008). Sinclair, Julie R. et al. "Tularemia in a Park, Philadelphia ... Title : Tularemia in a Park, Philadelphia, Pennsylvania Personal Author(s) : Sinclair, Julie R.;Newton, Alisa;Hinshaw, Keith; ... 2008). Tularemia in a Park, Philadelphia, Pennsylvania. 14(9). Sinclair, Julie R. et al. " ...
The rash of tick tularemia is seen here on the arm of a5-year-old boy. He also had a tick bite on his back that becamenecrotic ... the prognosis for tularemia is usually good.Ulceroglandular tularemia is the most commonform of tick tularemia. All forms ... The rash of tick tularemia is seen here on the arm of a5-year-old boy. He also had a tick bite on his back that becamenecrotic ... The rash of tick tularemia is seen here on the arm of a5-year-old boy. He also had a tick bite on his back that becamenecrotic ...
... Tularemia serology, If positive Tularemia IgM ELISA. Tular: Request Form from EU. Tular: Request Form from ...
  • Tularemia, also known as rabbit fever, is an infectious disease caused by the bacterium Francisella tularensis. (wikipedia.org)
  • Tularemia is caused by the bacteria Francisella tularensis which is typically spread by ticks, deer flies, and contact with infected animals. (wikipedia.org)
  • Francisella tularensis (tularemia). (medlineplus.gov)
  • Bloch KC, Schaffner W. Tularemia and other Francisella infections. (medlineplus.gov)
  • Tularemia is a naturally-occurring, tick transmitted disease of rabbits and rodents caused by the bacterium Francisella tularensis . (cabq.gov)
  • Tularemia, also known as Rabbit Fever, is caused by the bacteria Francisella tularensis , found in wild rodents and rabbits. (sandiegocounty.gov)
  • At the Annual Biophysical Society Meeting in San Francisco, Geoffrey K. Feld, a Postdoctoral researcher in the Physical&Life Sciences Directorate at Lawrence Livermore National Laboratory (LLNL), described the team's work to uncover the secrets of the bacterium Francisella tularensis , which causes tularemia. (science20.com)
  • The team, led by Thirumala-Devi Kanneganti, Ph.D., a member of the St. Jude Department of Immunology, found key receptors responsible for sensing DNA in cells infected by the tularemia-causing bacterium, Francisella . (stjude.org)
  • Francisella tularensis is a re-emerging organism causing more significant outbreaks of tularemia and fear of bioterrorism. (iasp-pain.org)
  • Tularemia, sometimes referred to as 'rabbit fever' is caused by the bacterium Francisella tularensis . (wormsandgermsblog.com)
  • Francisella tularensis is an intracellular bacterial pathogen which causes a potentially lethal disease named tularemia. (am-online.org)
  • However, a paucity of epidemiologic and ecologic knowledge hampers the investigation of tularemia outbreaks caused by the intracellular bacterium Francisella tularensis, although it is one of the most virulent pathogens known. (blogspot.com)
  • Tularemia is a bacterial disease caused by Francisella tularensis. (canna-pet.com)
  • Francisella tularensis can cause the zoonotic disease tularemia and is partitioned into subspecies due to differences in chromosomal organization and virulence. (nebraska.edu)
  • Tularemia is caused by the highly infectious F. tularensis bacteria. (cdc.gov)
  • U.S. weapons stores of tularemia bacteria were reported destroyed in 1973. (faqs.org)
  • The bacteria causes the disease tularemia . (medlineplus.gov)
  • Q. Can someone become infected with the tularemia bacteria from another person? (cdc.gov)
  • Q. How quickly would someone become sick if he or she were exposed to tularemia bacteria? (cdc.gov)
  • Q. What should someone do if he or she suspects exposure to tularemia bacteria? (cdc.gov)
  • A. If you suspect you were exposed to tularemia bacteria, see a doctor quickly. (cdc.gov)
  • The common hare or rabbit tick, Haemohysalis leporispalustris , which is found on rabbits and hares throughout North America, transmits the Tularemia bacteria between hares and can cause anemia. (alaska.gov)
  • Tularemia is a rare disease caused by the bacteria Francella tularensis . (publichealthontario.ca)
  • Residents are advised that tularemia-causing bacteria is present in some local mammals-especially rabbits and hares. (outbreaknewstoday.com)
  • If tularemia is caused by the bite of an infected insect or from bacteria entering a cut or scratch, it usually causes a skin ulcer and swollen glands. (outbreaknewstoday.com)
  • What causes tularemia? (alaska.gov)
  • Research led by scientists at St. Jude Children's Research Hospital has identified key molecules that trigger the immune system to launch an attack on the bacterium that causes tularemia. (stjude.org)
  • holarctica causes tularemia all over the Northern Hemisphere. (blogspot.com)
  • Fever is moderate or very high, and tularemia bacilli can be isolated from blood cultures at this stage. (wikipedia.org)
  • Reflecting the natural origin of the disease, tularemia is also known as rabbit fever. (faqs.org)
  • When tularemia is inhaled, the symptoms include the sudden development of a headache with accompanying high fever, chills, body aches (particularly in the lower back) and fatigue. (faqs.org)
  • Tularemia Information about tularemia, or rabbit fever, a disease primarily of rabbits but can also be found in rodents and transmitted to humans. (cabq.gov)
  • Cats with tularemia may have a high fever, a lack of appetite and act sluggish. (cabq.gov)
  • and The woman denied having a fever or other signs/ typhoid tularemia (fever without early signs/symp- symptoms of infection. (cdc.gov)
  • Tularemia, also called "rabbit fever", is, unlike anthrax or smallpox, the bioweapon you are least likely to know about. (science20.com)
  • We encountered a case of pulmonary tularemia with a unique presentation of severe headache and fever. (iasp-pain.org)
  • The specific aim was to evaluate the scientific support for laboratory diagnosis of human granulocytic anaplasmosis, rickettsiosis, neoehrlichiosis, babesiosis, hard tick relapsing fever, tularemia and bartonellosis, as well as tick-borne co-infections and persistent LB in spite of recommended standard antibiotic treatment. (frontiersin.org)
  • An infectious disease, tularemia also known as deer fly fever or rabbit fever is transmitted to humans by mammals while mode of transmission is often through insects. (yesdoct.com)
  • We've covered how tick bites can transmit Lyme Disease (East), as well as Rocky Mountain Spotted Fever (All US), but ticks, as well as small mammals like rabbits and mice (and in one instance wild hogs) can catch and transmit Tularemia , a highly contagious disease that often causes mass rodent die-offs. (colloidsforlife.com)
  • Not a U.S. FDA-approved use but has been used successfully to treat patients with tularemia. (cdc.gov)
  • As many as 20% of patients with tularemia have a rash, which may begin as blotchy, macular, or maculopapular and progress to pustular. (medscape.com)
  • Symptomatic and supportive care is applied for accompanying conditions (eg, osteomyelitis, pericarditis, peritonitis) in patients with tularemia, as clinically indicated. (medscape.com)
  • We performed whole genome sequencing (WGS) on six type B strains isolated from the blood of patients with tularemia within a one-year period from the same United States region, to better understand the associated pathogenicity. (nebraska.edu)
  • Depending on the site of infection, tularemia has six characteristic clinical variants: ulceroglandular (the most common type representing 75% of all forms), glandular, oropharyngeal, pneumonic, oculoglandular, and typhoidal. (wikipedia.org)
  • The number of cases of tularemia in the world is not known, as accurate statistics have not been kept, and because illnesses attributable to the bacterium go unreported. (faqs.org)
  • The inflammasome that attacks the tularemia bacterium is triggered by the sensor protein AIM2 that recognizes the tularemia DNA. (stjude.org)
  • Several types of antibiotics have been effective in treating tularemia infections. (cdc.gov)
  • According to the paper's first author, Si Ming Man, Ph.D., a postdoctoral fellow in St. Jude Immunology, the findings could lead to new protective treatments against tularemia, including drugs that can enhance the ability of IRF1, GBP or AIM2 to cure infections more quickly and effectively. (stjude.org)
  • While tularemia infections may result in a number of different clinical presentations, the most frequent symptoms are an ulcer at the site of the infection and swelling of lymph nodes. (publichealthontario.ca)
  • The oropharyngeal type of tularemia is discussed and four cases are presented. (johnshopkins.edu)
  • Etteldorf, James N. / Oropharyngeal tularemia . (johnshopkins.edu)
  • Tularemia is a highly infectious disease that kills more than 30 percent of those infected, if left untreated. (stjude.org)
  • Seroconversion from negative to positive IgM and/or IgG can also confirm the diagnosis when tularemia is suspected. (cdc.gov)
  • The diagnosis of tularemia usually is based on serology results. (medscape.com)
  • Therefore, diagnosis of tularemia in a person or pet should put both veterinarians and physicians on the lookout for further cases in all species. (wormsandgermsblog.com)
  • His axillary lymph nodesbecame palpable within 2 weeks after the tick bite.The diagnosis of ulceroglandular tularemia wasconfirmed by a blood agglutination titer of 1:4000. (patientcareonline.com)
  • The suspected diagnosis of Tularemia in wild rabbits in Montrose County, as well as two confirmed cases in domestic cats, has prompted the Montrose County Health and Human Services (HHS) to remind residents to take certain precautions against the bacterial infection. (outbreaknewstoday.com)
  • Early Diagnosis of Tularemia by Flow Cytometry, Czech Republic, 2003-2015 1 . (bvsalud.org)
  • Tularemia is and clinical signs depend on the route of infection. (cdc.gov)
  • Clinical manifestations of tularemia fall into two main forms: ulceroglandular (>90% of cases in Europe) 2 and typhoidal. (elsevier.es)
  • Eschar on thumb and under thumbnail at the site of a rabbit bite in a patient with tularemia. (medscape.com)
  • The WGS data were compared to the prototype strain for this subspecies, specifically FSC200, which was isolated from a patient with tularemia in Europe. (nebraska.edu)
  • Summer outbreaks of tularemia that occurred from 1995 through 2005 in 2 locations in Sweden affected 441 persons. (blogspot.com)
  • A vaccine is available for tularemia. (faqs.org)
  • Q. Is there a vaccine available for tularemia? (cdc.gov)
  • An Uncommon Presentation of Pulmonary Tularemia: A Case Report and Literature Review. (iasp-pain.org)
  • The patient responded well to antibiotic therapy;the prognosis for tularemia is usually good.Ulceroglandular tularemia is the most commonform of tick tularemia. (patientcareonline.com)
  • Except for the ulcer at the site of infection the rest of the symptoms are same as ulceroglandular tularemia. (yesdoct.com)
  • Rodents, rabbits, and hares often serve as reservoir hosts, but waterborne infection accounts for 5-10% of all tularemia in the United States. (wikipedia.org)
  • Q. Can tularemia be effectively treated with antibiotics? (cdc.gov)
  • Tularemia can be effectively treated with antibiotics, therefore should you have any of these early signs, seek medical attention as soon as possible. (outbreaknewstoday.com)
  • Transmission of tularemia from infected pets to humans is also a concern. (wormsandgermsblog.com)
  • Little is known about natural reservoirs of tularemia, F. tularensis transmission mechanisms to humans, and factors influencing the often irregular pattern of outbreaks. (blogspot.com)
  • For comparison, 20-64 humans were reported with tularemia from 2000 through 2006 in the tularemia-endemic US states of Arkansas and Missouri, from a population of ≈8.3 million (annual incidence rate 0.23-0.76/100,000 persons) (8). (blogspot.com)
  • Tularemia is a bacterial infection most commonly transmitted to humans that have handled infected animals. (outbreaknewstoday.com)
  • How do humans catch Tularemia? (colloidsforlife.com)
  • Dogs should not be allowed to hunt rabbits in areas where tularemia is endemic. (wormsandgermsblog.com)
  • Tularemia is endemic in Sweden, with seasonal outbreaks and a patchy geographic distribution. (blogspot.com)
  • Although difficult to diagnose, tularemia can be treated with antibiotics, and most patients completely recover. (sandiegocounty.gov)
  • If left untreated, tularemia can persist for weeks, even months, and can be fatal. (faqs.org)
  • We demonstrate a strategy to enhance epidemiologic investigations of tularemia by combining geographic data collected from patient interviews and high-resolution genotyping of F. tularensis subsp. (blogspot.com)
  • Patients were infected mainly from mosquito bites and had an influenza-like illness, a primary skin ulcer, and enlargement of lymph nodes, the ulceroglandular form of tularemia (5,6). (blogspot.com)
  • A. The incubation period (the time from being exposed to becoming ill) for tularemia is typically 3 to 5 days, but can range from 1 to 14 days. (cdc.gov)
  • holarctica isolates recovered from tularemia patients. (blogspot.com)
  • Q. What are the signs and symptoms of tularemia? (cdc.gov)
  • A. The signs and symptoms people develop depend on how they are exposed to tularemia. (cdc.gov)
  • Introducing the new Tularemia International Society (TULISOC) online membership system. (tularemia.org)
  • Tularemia is a bacterial disease that affects people and many species of wild and domestic animals. (merckvetmanual.com)
  • The tularaemia annual report for 2019 reported 1,463 confirmed cases of tularaemia in EU/EEA countries, with a notification rate of 0.3 cases per 100,000 of the population. (scot.nhs.uk)
  • Tularemia naturally occurs over much of North America and Europe. (faqs.org)
  • Human tularemia naturally occurs only in biotopes in the Northern Hemisphere. (blogspot.com)
  • We report the case of a pregnant woman with with cutaneous ulcerations and marked lymph- tularemia in Serbia. (cdc.gov)
  • If tests come back positive for tularemia, warning signs are posted in the area to inform the public on how to avoid ticks and protect themselves and their pets from this serious disease. (sandiegocounty.gov)
  • Tularemia is usually a rural disease and has been reported in all U.S. states except Hawaii. (cdc.gov)
  • Tularemia is a widespread disease in animals. (cdc.gov)
  • 3 In Spain, it was an uncommon disease until 1997, when the first tularemia outbreak occurred in Castilla y León. (elsevier.es)
  • In both locations, disease clusters were associated with recreational areas beside water, and genetic subpopulations were present throughout the tularemia season and persisted over years. (blogspot.com)
  • High-resolution genotyping in combination with patients' statements about geographic places of disease transmission provided valuable indications of likely sources of infection and the causal genotypes during these tularemia outbreaks. (blogspot.com)
  • Dogs and cats can die from tularemia. (alaska.gov)
  • Tularemia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (childrensmercy.org)
  • Gentamicin is preferred for treatment of severe tularemia. (cdc.gov)
  • The severe form of tularemia can kill up to 60% of those who are infected if treatment is not given. (faqs.org)
  • Tularemia prophylaxis is recommended in cases of laboratory exposure to infectious materials. (cdc.gov)
  • In Bernalillo County, tularemia infected animals and human cases have occurred mainly in the East Mountains communities and the Western Foothills of the Sandia Mountains. (cabq.gov)
  • About 200 human cases of tularemia are reported each year in the United States. (cdc.gov)
  • A study of 266 authenticated cases of tularemia in California occurring from 1927-1951 showed that 81 per cent were contracted from wild rabbits. (ajtmh.org)
  • The incidence of tularemia in the decade 1933-1942 was 16 cases a year but it has declined during the last ten years to an average of 6 cases which may in part be due to decreased reporting by clinicians who now have an effective antibiotic at hand. (ajtmh.org)
  • Tularemia can be serious or fatal without adequate treatment. (cdc.gov)
  • Tularemia can be fatal if the person is not treated with appropriate antibiotics. (cdc.gov)
  • Because tularemia is a zoonosis and little ecologic information exists about the causal organism, its prevention and control may require the development of novel outbreak investigation strategies. (blogspot.com)
  • In California, the American Dog Tick and the Pacific Coast Tick can transmit tularemia. (sandiegocounty.gov)
  • Preventing tick bites, handling carcasses carefully, and disinfecting water can reduce the risk of tularemia. (msdmanuals.com)
  • The Vector Control Program routinely collects, identifies, and tests ticks for tularemia and other tick-borne pathogens. (sandiegocounty.gov)
  • The incidence of tularemia in California does not warrant its consideration as a major public health problem. (ajtmh.org)
  • Q. Does tularemia occur naturally in the United States? (cdc.gov)
  • Where does tularemia occur? (alaska.gov)