A gamma-emitting radionuclide imaging agent used primarily in skeletal scintigraphy. Because of its absorption by a variety of tumors, it is useful for the detection of neoplasms.
The first artificially produced element and a radioactive fission product of URANIUM. Technetium has the atomic symbol Tc, atomic number 43, and atomic weight 98.91. All technetium isotopes are radioactive. Technetium 99m (m=metastable) which is the decay product of Molybdenum 99, has a half-life of about 6 hours and is used diagnostically as a radioactive imaging agent. Technetium 99 which is a decay product of technetium 99m, has a half-life of 210,000 years.
A nontoxic radiopharmaceutical that is used in the clinical evaluation of hepatobiliary disorders in humans.
A nontoxic radiopharmaceutical that is used in RADIONUCLIDE IMAGING for the clinical evaluation of hepatobiliary disorders in humans.
A gamma-emitting radionuclide imaging agent used for the diagnosis of diseases in many tissues, particularly in the gastrointestinal system, liver, and spleen.
A radiopharmaceutical used extensively in cholescintigraphy for the evaluation of hepatobiliary diseases. (From Int Jrnl Rad Appl Inst 1992;43(9):1061-4)
A radionuclide imaging agent used primarily in scintigraphy or tomography of the heart to evaluate the extent of the necrotic myocardial process. It has also been used in noninvasive tests for the distribution of organ involvement in different types of amyloidosis and for the evaluation of muscle necrosis in the extremities.
A gamma-emitting radionuclide imaging agent used for the diagnosis of diseases in many tissues, particularly in cardiovascular and cerebral circulation.
A technetium imaging agent used in renal scintigraphy, computed tomography, lung ventilation imaging, gastrointestinal scintigraphy, and many other procedures which employ radionuclide imaging agents.
Inorganic compounds that contain TECHNETIUM as an integral part of the molecule. Technetium 99m (m=metastable) is an isotope of technetium that has a half-life of about 6 hours. Technetium 99, which has a half-life of 210,000 years, is a decay product of technetium 99m.
Organic compounds that contain technetium as an integral part of the molecule. These compounds are often used as radionuclide imaging agents.
A trace element that is required in bone formation. It has the atomic symbol Sn, atomic number 50, and atomic weight 118.71.
A gamma-emitting RADIONUCLIDE IMAGING agent used in the evaluation of regional cerebral blood flow and in non-invasive dynamic biodistribution studies and MYOCARDIAL PERFUSION IMAGING. It has also been used to label leukocytes in the investigation of INFLAMMATORY BOWEL DISEASES.
A technetium imaging agent used to reveal blood-starved cardiac tissue during a heart attack.
A nontoxic radiopharmaceutical that is used in the diagnostic imaging of the renal cortex.
A technetium diagnostic aid used in renal function determination.
The production of an image obtained by cameras that detect the radioactive emissions of an injected radionuclide as it has distributed differentially throughout tissues in the body. The image obtained from a moving detector is called a scan, while the image obtained from a stationary camera device is called a scintiphotograph.
A gamma-emitting radionuclide imaging agent used for the diagnosis of diseases in many tissues, particularly in the gastrointestinal system, cardiovascular and cerebral circulation, brain, thyroid, and joints.
Compounds that are used in medicine as sources of radiation for radiotherapy and for diagnostic purposes. They have numerous uses in research and industry. (Martindale, The Extra Pharmacopoeia, 30th ed, p1161)
Compounds that contain the radical R2C=N.OH derived from condensation of ALDEHYDES or KETONES with HYDROXYLAMINE. Members of this group are CHOLINESTERASE REACTIVATORS.
Pathologic inclusions occurring in erythrocytes.
Poly or pyrophosphates of tin. In conjunction with radioactive technetium these compounds are used as bone-scanning agents and in scintigraphy to diagnose myocardial and cerebral infarction.
Inorganic salts of phosphoric acid that contain two phosphate groups.
Pollutants, present in soil, which exhibit radioactivity.
Inorganic compounds that contain tin as an integral part of the molecule.
Compounds that contain the triphenylmethane aniline structure found in rosaniline. Many of them have a characteristic magenta color and are used as COLORING AGENTS.
A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image.
Techniques for labeling a substance with a stable or radioactive isotope. It is not used for articles involving labeled substances unless the methods of labeling are substantively discussed. Tracers that may be labeled include chemical substances, cells, or microorganisms.
A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
'Sugar acids' are organic compounds derived from sugars through various processes, characterized by the presence of both a carboxyl group (-COOH) and a hydroxyl group (-OH) in their molecular structure, often found in food sources like fruits and used in industries such as food, pharmaceutical, and cosmetic.
Inorganic or organic compounds derived from phosphine (PH3) by the replacement of H atoms. (From Grant & Hackh's Chemical Dictionary, 5th ed)
Rhenium. A metal, atomic number 75, atomic weight 186.2, symbol Re. (Dorland, 28th ed)
Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.
Use of radiolabeled antibodies for diagnostic imaging of neoplasms. Antitumor antibodies are labeled with diverse radionuclides including iodine-131, iodine-123, indium-111, or technetium-99m and injected into the patient. Images are obtained by a scintillation camera.
Organic compounds containing the -CN radical. The concept is distinguished from CYANIDES, which denotes inorganic salts of HYDROGEN CYANIDE.
Isotopes that exhibit radioactivity and undergo radioactive decay. (From Grant & Hackh's Chemical Dictionary, 5th ed & McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Unstable isotopes of xenon that decay or disintegrate emitting radiation. Xe atoms with atomic weights 121-123, 125, 127, 133, 135, 137-145 are radioactive xenon isotopes.
A class of compounds of the type R-M, where a C atom is joined directly to any other element except H, C, N, O, F, Cl, Br, I, or At. (Grant & Hackh's Chemical Dictionary, 5th ed)
A diagnostic procedure used to determine whether LYMPHATIC METASTASIS has occurred. The sentinel lymph node is the first lymph node to receive drainage from a neoplasm.
The evacuation of food from the stomach into the duodenum.
Organic compounds that contain phosphorus as an integral part of the molecule. Included under this heading is broad array of synthetic compounds that are used as PESTICIDES and DRUGS.
The hollow, muscular organ that maintains the circulation of the blood.
Colloids with a gaseous dispersing phase and either liquid (fog) or solid (smoke) dispersed phase; used in fumigation or in inhalation therapy; may contain propellant agents.

Prognostic significance of extent of disease in bone in patients with androgen-independent prostate cancer. (1/414)

PURPOSE: To evaluate the prognostic significance of a bone scan index (BSI) based on the weighted proportion of tumor involvement in individual bones, in relation to other factors and to survival in patients with androgen-independent prostate cancer. PATIENTS AND METHODS: Baseline radionuclide bone scans were reviewed in 191 assessable patients with androgen-independent disease who were enrolled onto an open, randomized trial of liarozole versus prednisone. The extent of skeletal involvement was assessed by scoring each scan using the BSI and independently according to the number of metastatic lesions. The relationship of the scored bone involvement to other known prognostic factors was explored in single- and multiple-variable analyses. RESULTS: In single-variable analyses, the pretreatment factors found to be associated with survival were age (P = .0446), performance status (P = .0005), baseline prostate-specific antigen (P = .0001), hemoglobin (P = .0001), alkaline phosphatase (P = .0002), AST (P = .0021), lactate dehydrogenase (P = .0001), and treatment (P = .0098). The extent of osseous disease was significant using both the BSI (P = .0001) and the number of lesions present (P = .0001). In multiple-variable proportional hazards analyses, only BSI, age, hemoglobin, lactate dehydrogenase, and treatment arm were associated with survival. When the patient population was divided into three equal groups, with BSI values of < 1.4%, 1.4% to 5.1%, and > 5.1%, median survivals of 18.3, 15.5, and 8.1 months, respectively, were observed (P = .0079). CONCLUSION: The BSI quantifies the extent of skeletal involvement by tumor. It allows the identification of patients with distinct prognoses for stratification in clinical trials. Further study is needed to assess the utility of serial BSI determinations in monitoring treatment effects. The BSI may be particularly useful in the evaluation of agents for which prostate-specific antigen changes do not reflect clinical outcomes accurately.  (+info)

Increased renal retention of 99mTc-methylene diphosphonate after nephron-sparing surgery. (2/414)

Nephron-sparing surgery has become established as an effective treatment for localized renal cell carcinoma when preservation of renal function is necessary. The surgery usually requires temporary renal artery occlusion and may induce ischemic renal damage. In this study, we retrospectively evaluated renal activity on bone scintigraphy after nephron-sparing surgery. METHODS: Eleven patients who underwent nephron-sparing surgery for renal cell carcinoma and had a normal contralateral kidney were studied. A total of 12 bone scintigraphy images with 99mTc-labeled methylene diphosphonate were obtained within 1 y after surgery in these patients to assess skeletal metastasis. Activity in the spared renal parenchyma was compared visually with that in the contralateral normal kidney. RESULTS: The tumor was successfully resected in every patient, and no clinically significant complications occurred. Activity in the spared renal parenchyma was elevated in six of seven examinations performed within 21 d after surgery. In three examinations, the increase in renal activity was heterogeneous, being relatively prominent near the surgical margin. Increased renal activity was not observed on five examinations performed 3 mo or more after surgery. CONCLUSION: Renal retention of bone-seeking agents is elevated in the early period after nephron-sparing surgery, probably as a result of ischemic insult during the surgical procedure. Bone scintigraphy may aid in evaluating the presence and degree of ischemic damage of the spared renal parenchyma.  (+info)

Bone agent localization in hepatic metastases. (3/414)

We present the bone scintigrams of two patients, which demonstrate diffuse extraosseous uptake of a bone agent in metastatic masses in the liver, one from a primary lung tumor and one from a primary breast tumor. The bone imaging agent did not localize in the brain metastases in these patients. CTs of the abdomen in both patients showed massive metastases in the liver with multiple areas of tumor necrosis. The CT of the abdomen of the breast cancer patient showed multiple small hepatic calcifications. Autopsy revealed massive tumor necrosis with calcifications in the enlarged liver. In routine bone scintigraphy, diffuse uptake of bone agents in the liver of a patient with a known malignancy should be considered suggestive of massive hepatic metastases.  (+info)

Multiple extra-bone accumulations of technetium-99m-HMDP. (4/414)

Bone scintigraphy was performed on a woman 2 y and 10 mo after surgery for rectal cancer. Intense extra-bone accumulations of 99mTc-HMDP were visible in an aortic atherosclerosis lesion and in a metastatic liver tumor. Uptake in the metastatic lesion was confirmed by x-ray CT. Uptake in the aortic lesion was shown as typical calcification by x-ray CT.  (+info)

Unexpected stomach uptake of technetium-99m-MDP. (5/414)

Two pediatric cases are described in which the results of each patient's bone scan demonstrated abnormal stomach uptake. There have been a number of reports in the literature describing stomach uptake of bone agents, however, it is an uncommon finding.  (+info)

Localization of a bone imaging agent in a calcified hematoma. (6/414)

A patient with chronic renal failure and secondary hyperparathyroidism had iliac bone biopsy. The procedure was complicated by a soft-tissue hematoma, which had calcified. A 3-4-cm palpable mass was visible in the lower left abdominal wall. Intense uptake of 99mTc-HMDP corresponded with the location of the calcified hematoma in this patient.  (+info)

Myositis ossificans demonstrated by positive gallium-67 and technetium-99m-HMDP bone imaging but negative technetium-99m-MIBI imaging. (7/414)

Gallium-67-citrate and 99mTc-diphosphate bone imaging agents are localized in myositis ossificans, a tumor-like benign soft-tissue mass that makes it impossible to differentiate between malignant tumor and the infection/inflammatory process. We present such a myositis ossificans patient whose bone and 67Ga-citrate imagings showed increased uptake in the left thigh and two foci of the right gluteal region leading to inconclusive results. Technetium-99m-MIBI imaging showed the absence of substantial uptake in these regions. ACT scan confirmed myositis ossificans. The lack of 99mTc-MIBI uptake in myositis ossificans means that 99mTc-MIBI imaging may be useful in the differential diagnosis.  (+info)

Bone scintigraphy in chronic knee pain: comparison with magnetic resonance imaging. (8/414)

OBJECTIVE: To compare increased bone uptake of 99Tcm-MDP and magnetic resonance (MR) detected subchondral lesions, osteophytes, and cartilage defects in the knee in middle aged people with long-standing knee pain. METHODS: Fifty eight people (aged 41-58 years, mean 50) with chronic knee pain, with or without radiographic knee osteoarthritis, were examined with bone scintigraphy. The pattern and the grade of increased bone uptake was assessed. On the same day, a MR examination on a 1.0 T imager was performed. The presence and the grade of subchondral lesions, osteophytes, and cartilage defects were registered. RESULTS: The kappa values describing the correlation between increased bone uptake and MR detected subchondral lesions varied between 0.79 and 0.49, and between increased bone uptake and MR detected osteophytes or cartilage defects the values were < 0.54. The kappa values describing the correlation between the grade of bone uptake and the grade of the different MR findings was < 0.57. CONCLUSIONS: Good agreement was found between increased bone uptake and MR detected subchondral lesion. The agreement between increased bone uptake and osteophytes or cartilage defects was in general poor as well as the agreement between the grade of bone uptake and the grade of the MR findings.  (+info)

Technetium Tc 99m Medronate is a radiopharmaceutical agent used in nuclear medicine for bone scintigraphy. It is a technetium-labeled bisphosphonate compound, which accumulates in areas of increased bone turnover and metabolism. This makes it useful for detecting and evaluating various bone diseases and conditions, such as fractures, tumors, infections, and arthritis.

The "Tc 99m" refers to the radioisotope technetium-99m, which has a half-life of approximately 6 hours and emits gamma rays that can be detected by a gamma camera. The medronate component is a bisphosphonate molecule that binds to hydroxyapatite crystals in bone tissue, allowing the radiolabeled compound to accumulate in areas of active bone remodeling.

Overall, Technetium Tc 99m Medronate is an important tool in nuclear medicine for diagnosing and managing various musculoskeletal disorders.

Technetium is not a medical term itself, but it is a chemical element with the symbol Tc and atomic number 43. However, in the field of nuclear medicine, which is a branch of medicine that uses small amounts of radioactive material to diagnose or treat diseases, Technetium-99m (a radioisotope of technetium) is commonly used for various diagnostic procedures.

Technetium-99m is a metastable nuclear isomer of technetium-99, and it emits gamma rays that can be detected outside the body to create images of internal organs or tissues. It has a short half-life of about 6 hours, which makes it ideal for diagnostic imaging since it decays quickly and reduces the patient's exposure to radiation.

Technetium-99m is used in a variety of medical procedures, such as bone scans, lung scans, heart scans, liver-spleen scans, brain scans, and kidney scans, among others. It can be attached to different pharmaceuticals or molecules that target specific organs or tissues, allowing healthcare professionals to assess their function or identify any abnormalities.

Technetium Tc 99m Diethyl-iminodiacetic Acid (Tc 99m DTPA) is a radiopharmaceutical agent used in medical imaging. It is a technetium-labeled compound, where the radioisotope technetium-99m is bound to diethyl-iminodiacetic acid (DTPA). This complex is used as a renal agent for performing nuclear medicine imaging studies to assess kidney function and structure.

Technetium-99m is a metastable isotope of technetium that emits gamma rays, making it suitable for medical imaging. When Tc 99m DTPA is injected into the patient's body, it is excreted primarily by the kidneys through glomerular filtration and tubular secretion. The gamma rays emitted by technetium-99m are detected by a gamma camera, which generates images of the distribution and excretion of the radiopharmaceutical within the kidneys. This information helps physicians evaluate kidney function, detect abnormalities such as obstructions or tumors, and monitor the effectiveness of treatments.

It is essential to handle and administer Tc 99m DTPA with care due to its radioactive nature, following proper safety guidelines and regulations to ensure patient and staff safety.

Technetium Tc 99m Lidofenin is a radiopharmaceutical used in nuclear medicine imaging procedures, specifically for hepatobiliary scintigraphy. It is a technetium-labeled compound, where the radioisotope technetium-99m (^99m^Tc) is bound to lidofenin, a liver-imaging agent.

The compound is used to assess the function and anatomy of the liver, gallbladder, and biliary system. After intravenous administration, Technetium Tc 99m Lidofenin is taken up by hepatocytes (liver cells) and excreted into the bile ducts and ultimately into the small intestine. The distribution and excretion of this radiopharmaceutical can be monitored using a gamma camera, providing functional information about the liver and biliary system.

It is essential to note that the use of Technetium Tc 99m Lidofenin should be under the guidance and supervision of healthcare professionals trained in nuclear medicine, as its administration and handling require specific expertise and safety measures due to the radioactive nature of the compound.

Technetium Tc 99m Sulfur Colloid is a radioactive tracer used in medical imaging procedures, specifically in nuclear medicine. It is composed of tiny particles of sulfur colloid that are labeled with the radioisotope Technetium-99m. This compound is typically injected into the patient's body, where it accumulates in certain organs or tissues, depending on the specific medical test being conducted.

The radioactive emissions from Technetium Tc 99m Sulfur Colloid are then detected by a gamma camera, which produces images that can help doctors diagnose various medical conditions, such as liver disease, inflammation, or tumors. The half-life of Technetium-99m is approximately six hours, which means that its radioactivity decreases rapidly and is eliminated from the body within a few days.

Technetium Tc 99m Disofenin is not a medical condition, but rather a radiopharmaceutical used in diagnostic imaging. It is a radioactive tracer used in nuclear medicine scans, specifically for liver and biliary system imaging. The compound consists of the radioisotope Technetium-99m (Tc-99m) bonded to the pharmaceutical Disofenin.

The Tc-99m is a gamma emitter with a half-life of 6 hours, making it ideal for diagnostic imaging. When administered to the patient, the compound is taken up by the liver and excreted into the bile ducts and gallbladder, allowing medical professionals to visualize these structures using a gamma camera. This can help detect various conditions such as tumors, gallstones, or obstructions in the biliary system.

It's important to note that Technetium Tc 99m Disofenin is used diagnostically and not for therapeutic purposes. The radiation exposure from this compound is generally low and considered safe for diagnostic use. However, as with any medical procedure involving radiation, the benefits and risks should be carefully weighed and discussed with a healthcare professional.

Technetium Tc 99m Pyrophosphate (Tc-99m PYP) is a radiopharmaceutical agent used in nuclear medicine imaging, specifically myocardial perfusion imaging. It is a complex of technetium-99m, a metastable isotope of technetium, with pyrophosphate, a molecule that accumulates in damaged heart muscle tissue.

When injected into the patient's bloodstream, Tc-99m PYP is taken up by the heart muscle in proportion to its blood flow and the degree of damage or scarring (fibrosis). This allows for the detection and evaluation of conditions such as myocardial infarction (heart attack), cardiomyopathy, and heart transplant rejection.

The imaging procedure involves the injection of Tc-99m PYP, followed by the acquisition of images using a gamma camera, which detects the gamma rays emitted by the technetium-99m isotope. The resulting images provide information about the distribution and extent of heart muscle damage, helping physicians to make informed decisions regarding diagnosis and treatment planning.

Technetium Tc 99m Aggregated Albumin is a radiopharmaceutical preparation used in diagnostic imaging. It consists of radioactive technetium-99m (^99m^Tc) chemically bonded to human serum albumin, which has been aggregated to increase its size and alter its clearance from the body.

The resulting compound is injected into the patient's bloodstream, where it accumulates in the reticuloendothelial system (RES), including the liver, spleen, and bone marrow. The radioactive emission of technetium-99m can then be detected by a gamma camera, producing images that reflect the distribution and function of the RES.

This imaging technique is used to diagnose and monitor various conditions, such as liver disease, inflammation, or tumors. It provides valuable information about the patient's health status and helps guide medical decision-making.

Technetium Tc 99m Pentetate is a radioactive pharmaceutical preparation used as a radiopharmaceutical agent in medical imaging. It is a salt of technetium-99m, a metastable nuclear isomer of technetium-99, which emits gamma rays and has a half-life of 6 hours.

Technetium Tc 99m Pentetate is used in various diagnostic procedures, including renal imaging, brain scans, lung perfusion studies, and bone scans. It is distributed throughout the body after intravenous injection and is excreted primarily by the kidneys, making it useful for evaluating renal function and detecting abnormalities in the urinary tract.

The compound itself is a colorless, sterile, pyrogen-free solution that is typically supplied in a lead shielded container to protect against radiation exposure. It should be used promptly after preparation and handled with care to minimize radiation exposure to healthcare workers and patients.

Technetium compounds refer to chemical substances that contain the radioactive technetium (Tc) element. Technetium is a naturally rare element and does not have any stable isotopes, making it only exist in trace amounts in the Earth's crust. However, it can be produced artificially in nuclear reactors.

Technetium compounds are widely used in medical imaging as radioactive tracers in diagnostic procedures. The most common technetium compound is Technetium-99m (Tc-99m), which has a half-life of 6 hours and emits gamma rays that can be detected by external cameras. Tc-99m is often bound to various pharmaceuticals, such as methylene diphosphonate (MDP) or human serum albumin (HSA), to target specific organs or tissues in the body.

Technetium compounds are used in a variety of diagnostic procedures, including bone scans, lung perfusion scans, myocardial perfusion imaging, and brain scans. They provide valuable information about organ function, blood flow, and tissue metabolism, helping doctors diagnose various medical conditions such as cancer, heart disease, and bone fractures.

It is important to note that technetium compounds should only be used under the supervision of trained medical professionals due to their radioactive nature. Proper handling, administration, and disposal procedures must be followed to ensure safety and minimize radiation exposure.

Organotechnetium compounds are chemical substances that contain carbon-technetium bonds, where technetium is an element with the symbol Tc and atomic number 43. These types of compounds are primarily used in medical imaging as radioactive tracers due to the ability of technetium-99m to emit gamma rays. The organotechnetium compounds help in localizing specific organs, tissues, or functions within the body, making them useful for diagnostic purposes in nuclear medicine.

It is important to note that most organotechnetium compounds are synthesized from technetium-99m, which is generated from the decay of molybdenum-99. The use of these compounds requires proper handling and administration by trained medical professionals due to their radioactive nature.

I'm sorry for any confusion, but "Tin" does not have a medical definition. Tin is a chemical element with the symbol Sn and atomic number 50. It is a malleable, ductile, silvery-white post-transition metal. It is found in nature mainly as tin oxides and is obtained from the mineral cassiterite through mining and processing.

Tin has no known biological role in humans, animals, or plants, and it is not considered an essential nutrient. Small amounts of tin can be found in some foods and drinking water, but these levels are generally low and not considered harmful. High levels of tin can be toxic to the human body, causing symptoms such as nausea, vomiting, and diarrhea.

If you have any questions about a medical condition or treatment, I would recommend consulting with a healthcare professional for accurate information and guidance.

Technetium Tc 99m Exametazime is a radiopharmaceutical agent used in nuclear medicine imaging procedures. The compound consists of the radioisotope Technetium-99m (^99m^Tc) bonded to Exametazime, also known as HMPAO (hexamethylpropyleneamine oxime).

Once injected into the patient's bloodstream, Technetium Tc 99m Exametazime distributes evenly throughout the brain, crossing the blood-brain barrier and entering cells. The radioactive decay of Technetium-99m emits gamma rays that can be detected by a gamma camera, creating images of the brain's blood flow and distribution of the tracer.

This imaging technique is often used in cerebral perfusion studies to assess conditions such as stroke, epilepsy, or dementia, providing valuable information about regional cerebral blood flow and potential areas of injury or abnormality.

Technetium Tc 99m Sestamibi is a radiopharmaceutical compound used in medical imaging, specifically in myocardial perfusion scintigraphy. It is a technetium-labeled isonitrile chelate that is taken up by mitochondria in cells with high metabolic activity, such as cardiomyocytes (heart muscle cells).

Once injected into the patient's body, Technetium Tc 99m Sestamibi emits gamma rays, which can be detected by a gamma camera. This allows for the creation of images that reflect the distribution and function of the radiopharmaceutical within the heart muscle. The images can help identify areas of reduced blood flow or ischemia, which may indicate coronary artery disease.

The uptake of Technetium Tc 99m Sestamibi in other organs, such as the breast and thyroid, can also be used for imaging purposes, although its primary use remains in cardiac imaging.

Technetium Tc 99m Dimercaptosuccinic Acid (DMSA) is a radiopharmaceutical agent used in nuclear medicine imaging procedures. The compound is made up of the radioisotope Technetium-99m, which emits gamma rays that can be detected by a gamma camera, and dimercaptosuccinic acid, which binds to certain types of metal ions in the body.

In medical imaging, Technetium Tc 99m DMSA is typically used to visualize the kidneys and detect any abnormalities such as inflammation, infection, or tumors. The compound is taken up by the renal tubules in the kidneys, allowing for detailed images of the kidney structure and function to be obtained.

It's important to note that the use of Technetium Tc 99m DMSA should be under the supervision of a trained medical professional, as with any radiopharmaceutical agent, due to the radiation exposure involved in its use.

Technetium Tc 99m Mertiatide is a radiopharmaceutical used in nuclear medicine imaging procedures. It is a technetium-labeled compound, where the radioisotope technetium-99m (^99m^Tc) is bound to mercaptoacetyltriglycine (MAG3). The resulting complex is known as ^99m^Tc-MAG3 or Technetium Tc 99m Mertiatide.

This radiopharmaceutical is primarily used for renal function assessment, including evaluation of kidney blood flow, glomerular filtration rate (GFR), and detection of renal obstructions or other abnormalities. After intravenous administration, Technetium Tc 99m Mertiatide is rapidly excreted by the kidneys, allowing for visualization and quantification of renal function through gamma camera imaging.

It's important to note that the use of radiopharmaceuticals should be performed under the guidance of a qualified healthcare professional, as they involve the administration of radioactive materials for diagnostic purposes.

Radionuclide imaging, also known as nuclear medicine, is a medical imaging technique that uses small amounts of radioactive material, called radionuclides or radiopharmaceuticals, to diagnose and treat various diseases and conditions. The radionuclides are introduced into the body through injection, inhalation, or ingestion and accumulate in specific organs or tissues. A special camera then detects the gamma rays emitted by these radionuclides and converts them into images that provide information about the structure and function of the organ or tissue being studied.

Radionuclide imaging can be used to evaluate a wide range of medical conditions, including heart disease, cancer, neurological disorders, gastrointestinal disorders, and bone diseases. The technique is non-invasive and generally safe, with minimal exposure to radiation. However, it should only be performed by qualified healthcare professionals in accordance with established guidelines and regulations.

Sodium Pertechnetate Tc 99m is a radioactive pharmaceutical preparation used in medical diagnostic imaging. It is a technetium-99m radiopharmaceutical, where technetium-99m is a metastable nuclear isomer of technetium-99, which emits gamma rays and has a half-life of 6 hours. Sodium Pertechnetate Tc 99m is used as a contrast agent in various diagnostic procedures, such as imaging of the thyroid, salivary glands, or the brain, to evaluate conditions like inflammation, tumors, or abnormalities in blood flow. It is typically administered intravenously, and its short half-life ensures that the radiation exposure is limited.

Radiopharmaceuticals are defined as pharmaceutical preparations that contain radioactive isotopes and are used for diagnosis or therapy in nuclear medicine. These compounds are designed to interact specifically with certain biological targets, such as cells, tissues, or organs, and emit radiation that can be detected and measured to provide diagnostic information or used to destroy abnormal cells or tissue in therapeutic applications.

The radioactive isotopes used in radiopharmaceuticals have carefully controlled half-lives, which determine how long they remain radioactive and how long the pharmaceutical preparation remains effective. The choice of radioisotope depends on the intended use of the radiopharmaceutical, as well as factors such as its energy, range of emission, and chemical properties.

Radiopharmaceuticals are used in a wide range of medical applications, including imaging, cancer therapy, and treatment of other diseases and conditions. Examples of radiopharmaceuticals include technetium-99m for imaging the heart, lungs, and bones; iodine-131 for treating thyroid cancer; and samarium-153 for palliative treatment of bone metastases.

The use of radiopharmaceuticals requires specialized training and expertise in nuclear medicine, as well as strict adherence to safety protocols to minimize radiation exposure to patients and healthcare workers.

Oximes are a class of chemical compounds that contain the functional group =N-O-, where two organic groups are attached to the nitrogen atom. In a clinical context, oximes are used as antidotes for nerve agent and pesticide poisoning. The most commonly used oxime in medicine is pralidoxime (2-PAM), which is used to reactivate acetylcholinesterase that has been inhibited by organophosphorus compounds, such as nerve agents and certain pesticides. These compounds work by forming a bond with the phosphoryl group of the inhibited enzyme, allowing for its reactivation and restoration of normal neuromuscular function.

Erythrocyte inclusions refer to the presence of abnormal structures or substances within red blood cells (erythrocytes). These inclusions can be composed of various materials such as proteins, pigments, or foreign bodies. They may be seen in a variety of medical conditions and can provide important diagnostic clues.

Some examples of erythrocyte inclusions include:

1. Howell-Jolly bodies: small remnants of nuclear material left behind after the red blood cell matures. They are typically seen in individuals with an absent or nonfunctional spleen.
2. Heinz bodies: denatured hemoglobin that forms clumps within the red blood cells. They can be seen in conditions such as hemolytic anemia, G6PD deficiency, and exposure to certain drugs or toxins.
3. Pappenheimer bodies: aggregates of iron-containing proteins called ferritin or hemosiderin. They are typically seen in conditions associated with increased red blood cell destruction, such as thalassemia or lead poisoning.
4. Basophilic stippling: small, basophilic (blue-staining) granules within the red blood cells. They can be seen in various conditions, including lead poisoning, megaloblastic anemias, and certain inherited disorders.
5. Parasites: organisms such as malaria or babesia that infect and multiply within the red blood cells.

The detection of erythrocyte inclusions typically requires specialized testing, such as peripheral blood smears stained with specific dyes to highlight the abnormal structures. The presence and type of inclusions can help diagnose certain medical conditions and guide appropriate treatment.

I'm sorry for any confusion, but "Tin Polyphosphates" is not a recognized medical term or concept. It appears to be a chemical compound, specifically a polyphosphate complex of tin. Polyphosphates are chains of phosphate groups, and in this case, they are bound to a tin (Sn) atom.

Tin polyphosphates may have various industrial applications, such as flame retardants or corrosion inhibitors, but they do not have a specific relevance to medical definition. If you have any questions about the chemical properties or uses of tin polyphosphates in a non-medical context, I would recommend consulting a chemistry or materials science resource.

Diphosphates, also known as pyrophosphates, are chemical compounds that contain two phosphate groups joined together by an oxygen atom. The general formula for a diphosphate is P~PO3~2-, where ~ represents a bond. Diphosphates play important roles in various biological processes, such as energy metabolism and cell signaling. In the context of nutrition, diphosphates can be found in some foods, including milk and certain vegetables.

Radioactive soil pollutants refer to radioactive substances that contaminate and negatively impact the chemical, physical, and biological properties of soil. These pollutants can arise from various sources such as nuclear accidents, industrial activities, agricultural practices, and military testing. They include radionuclides such as uranium, plutonium, cesium-137, and strontium-90, among others.

Exposure to radioactive soil pollutants can have serious health consequences for humans and other living organisms. Direct contact with contaminated soil can result in radiation exposure, while ingestion or inhalation of contaminated soil particles can lead to internal radiation exposure. This can increase the risk of cancer, genetic mutations, and other health problems.

Radioactive soil pollutants can also have negative impacts on the environment, such as reducing soil fertility, disrupting ecosystems, and contaminating water sources. Therefore, it is essential to monitor and regulate radioactive soil pollution to protect human health and the environment.

Tin compounds refer to chemical substances that contain tin (Sn) combined with one or more other elements. Tin can form various types of compounds, including oxides, sulfides, halides, and organometallic compounds. These compounds have different properties and uses depending on the other element(s) they are combined with.

For example:

* Tin (IV) oxide (SnO2) is a white powder used as an opacifying agent in glass and ceramics, as well as a component in some types of batteries.
* Tin (II) sulfide (SnS) is a black or brown solid used in the manufacture of some types of semiconductors.
* Tin (IV) chloride (SnCl4) is a colorless liquid used as a catalyst in the production of polyvinyl chloride (PVC) and other plastics.
* Organotin compounds, such as tributyltin (TBT), are used as biocides and antifouling agents in marine paints. However, they have been found to be toxic to aquatic life and are being phased out in many countries.

Rosaniline dyes are a type of basic dye that were first synthesized in the late 19th century. They are named after rosaniline, which is a primary chemical used in their production. Rosaniline dyes are characterized by their ability to form complexes with metal ions, which can then bind to proteins and other biological molecules. This property makes them useful as histological stains, which are used to highlight specific structures or features within tissues and cells.

Rosaniline dyes include a range of different chemicals, such as methyl violet, crystal violet, and basic fuchsin. These dyes are often used in combination with other staining techniques to provide contrast and enhance the visibility of specific cellular components. For example, they may be used to stain nuclei, cytoplasm, or other structures within cells, allowing researchers and clinicians to visualize and analyze tissue samples more effectively.

It's worth noting that some rosaniline dyes have been found to have potential health hazards, particularly when used in certain forms or concentrations. Therefore, it's important to follow proper safety protocols when handling these chemicals and to use them only under the guidance of trained professionals.

Emission-Computed Tomography, Single-Photon (SPECT) is a type of nuclear medicine imaging procedure that generates detailed, three-dimensional images of the distribution of radioactive pharmaceuticals within the body. It uses gamma rays emitted by a radiopharmaceutical that is introduced into the patient's body, and a specialized gamma camera to detect these gamma rays and create tomographic images. The data obtained from the SPECT imaging can be used to diagnose various medical conditions, evaluate organ function, and guide treatment decisions. It is commonly used to image the heart, brain, and bones, among other organs and systems.

Isotope labeling is a scientific technique used in the field of medicine, particularly in molecular biology, chemistry, and pharmacology. It involves replacing one or more atoms in a molecule with a radioactive or stable isotope of the same element. This modified molecule can then be traced and analyzed to study its structure, function, metabolism, or interaction with other molecules within biological systems.

Radioisotope labeling uses unstable radioactive isotopes that emit radiation, allowing for detection and quantification of the labeled molecule using various imaging techniques, such as positron emission tomography (PET) or single-photon emission computed tomography (SPECT). This approach is particularly useful in tracking the distribution and metabolism of drugs, hormones, or other biomolecules in living organisms.

Stable isotope labeling, on the other hand, employs non-radioactive isotopes that do not emit radiation. These isotopes have different atomic masses compared to their natural counterparts and can be detected using mass spectrometry. Stable isotope labeling is often used in metabolic studies, protein turnover analysis, or for identifying the origin of specific molecules within complex biological samples.

In summary, isotope labeling is a versatile tool in medical research that enables researchers to investigate various aspects of molecular behavior and interactions within biological systems.

Etidronic acid is a type of medication known as a bisphosphonate. It is used to treat conditions such as Paget's disease, osteoporosis, and certain types of cancer that have spread to the bones.

Etidronic acid works by inhibiting the activity of cells called osteoclasts, which are responsible for breaking down bone tissue. This helps to slow down the process of bone loss and can increase bone density, making bones stronger and less likely to break.

The medication is available in the form of a solution that is given intravenously (through a vein) in a hospital or clinic setting. It may be given as a single dose or as multiple doses over a period of time, depending on the condition being treated and the individual patient's needs.

As with any medication, etidronic acid can have side effects, including nausea, vomiting, diarrhea, and bone pain. It is important for patients to discuss the potential risks and benefits of this medication with their healthcare provider before starting treatment.

Sugar acids are a type of organic acid that are derived from sugars through the process of hydrolysis or oxidation. They have complex structures and can be found in various natural sources such as fruits, vegetables, and honey. In the medical field, sugar acids may be used in the production of pharmaceuticals and other chemical products.

Some common examples of sugar acids include:

* Gluconic acid, which is derived from glucose and has applications in the food industry as a preservative and stabilizer.
* Lactic acid, which is produced by fermentation of carbohydrates and is used in the production of various pharmaceuticals, foods, and cosmetics.
* Citric acid, which is found in citrus fruits and is widely used as a flavoring agent, preservative, and chelating agent in food, beverages, and personal care products.

It's worth noting that while sugar acids have important applications in various industries, they can also contribute to tooth decay and other health problems when consumed in excess. Therefore, it's important to consume them in moderation as part of a balanced diet.

Phosphines are a class of organic compounds characterized by a phosphorus atom bonded to three organic groups and a hydrogen atom, with the general formula of PRR'R''H. They are important in various chemical reactions as reducing agents and catalysts. In medicine, phosphines have no direct medical application. However, certain phosphine compounds have been studied for their potential use as pharmaceuticals, such as phosphinic acids which have shown promise as protease inhibitors used in the treatment of diseases like HIV and HCV. It is important to note that some phosphines are highly toxic and should be handled with care.

I'm sorry for any confusion, but "Rhenium" is not a medical term. It is a chemical element with the symbol "Re" and atomic number 75. Rhenium is a heavy, silvery-white, metallic element that is highly resistant to corrosion and is used in high-temperature alloys and electronics.

It does not have any direct medical relevance or application as a drug, treatment, or diagnostic tool in human medicine. However, like many other elements, rhenium compounds are being studied for their potential medicinal uses, such as in cancer therapy. But it's important to note that these are still in the research phase and have not yet been approved for use in humans.

Tissue distribution, in the context of pharmacology and toxicology, refers to the way that a drug or xenobiotic (a chemical substance found within an organism that is not naturally produced by or expected to be present within that organism) is distributed throughout the body's tissues after administration. It describes how much of the drug or xenobiotic can be found in various tissues and organs, and is influenced by factors such as blood flow, lipid solubility, protein binding, and the permeability of cell membranes. Understanding tissue distribution is important for predicting the potential effects of a drug or toxin on different parts of the body, and for designing drugs with improved safety and efficacy profiles.

Radioimmunodetection (RID) is a medical diagnostic technique that combines the specificity of antibodies with the sensitivity of radioisotopes to detect and locate antigens or tumor markers within the body. This technique involves labeling antibodies with radioactive isotopes, which are then introduced into the patient's body. The labeled antibodies bind to the target antigens, allowing for their detection and localization using external gamma cameras.

The process typically begins with the production of monoclonal or polyclonal antibodies that specifically recognize and bind to a particular antigen associated with a disease or condition. These antibodies are then labeled with radioisotopes such as technetium-99m, iodine-131, or indium-111, which emit gamma rays that can be detected by external imaging devices.

Once the labeled antibodies have been administered to the patient, they circulate throughout the body and bind to their respective antigens. The bound radioactive antibodies can then be imaged using a gamma camera or single-photon emission computed tomography (SPECT) scanner, providing information about the location, size, and distribution of the target antigens within the body.

Radioimmunodetection has been widely used in the detection and monitoring of various malignancies, including cancerous tumors and metastases, as well as inflammatory and infectious diseases. It offers several advantages over other diagnostic techniques, such as high sensitivity, specificity, and non-invasiveness, making it an essential tool in modern medical imaging and diagnostics.

Nitriles, in a medical context, refer to a class of organic compounds that contain a cyano group (-CN) bonded to a carbon atom. They are widely used in the chemical industry and can be found in various materials, including certain plastics and rubber products.

In some cases, nitriles can pose health risks if ingested, inhaled, or come into contact with the skin. Short-term exposure to high levels of nitriles can cause irritation to the eyes, nose, throat, and respiratory tract. Prolonged or repeated exposure may lead to more severe health effects, such as damage to the nervous system, liver, and kidneys.

However, it's worth noting that the medical use of nitriles is not very common. Some nitrile gloves are used in healthcare settings due to their resistance to many chemicals and because they can provide a better barrier against infectious materials compared to latex or vinyl gloves. But beyond this application, nitriles themselves are not typically used as medications or therapeutic agents.

Radioisotopes, also known as radioactive isotopes or radionuclides, are variants of chemical elements that have unstable nuclei and emit radiation in the form of alpha particles, beta particles, gamma rays, or conversion electrons. These isotopes are formed when an element's nucleus undergoes natural or artificial radioactive decay.

Radioisotopes can be produced through various processes, including nuclear fission, nuclear fusion, and particle bombardment in a cyclotron or other types of particle accelerators. They have a wide range of applications in medicine, industry, agriculture, research, and energy production. In the medical field, radioisotopes are used for diagnostic imaging, radiation therapy, and in the labeling of molecules for research purposes.

It is important to note that handling and using radioisotopes requires proper training, safety measures, and regulatory compliance due to their ionizing radiation properties, which can pose potential health risks if not handled correctly.

Xenon radioisotopes are unstable isotopes of the element xenon that emit radiation as they decay into more stable forms. These isotopes can be produced through various nuclear reactions and have a wide range of applications, including medical imaging and cancer treatment. Examples of commonly used xenon radioisotopes include xenon-127, xenon-131m, xenon-133, and xenon-135.

It's important to note that the use of radioisotopes in medical settings must be carefully regulated and monitored to ensure safety and minimize potential risks to patients and healthcare workers.

Organometallic compounds are a type of chemical compound that contain at least one metal-carbon bond. This means that the metal is directly attached to carbon atom(s) from an organic molecule. These compounds can be synthesized through various methods, and they have found widespread use in industrial and medicinal applications, including catalysis, polymerization, and pharmaceuticals.

It's worth noting that while organometallic compounds contain metal-carbon bonds, not all compounds with metal-carbon bonds are considered organometallic. For example, in classical inorganic chemistry, simple salts of metal carbonyls (M(CO)n) are not typically classified as organometallic, but rather as metal carbonyl complexes. The distinction between these classes of compounds can sometimes be subtle and is a matter of ongoing debate among chemists.

A sentinel lymph node biopsy is a surgical procedure used in cancer staging to determine if the cancer has spread beyond the primary tumor to the lymphatic system. This procedure involves identifying and removing the sentinel lymph node(s), which are the first few lymph nodes to which cancer cells are most likely to spread from the primary tumor site.

The sentinel lymph node(s) are identified by injecting a tracer substance (usually a radioactive material and/or a blue dye) near the tumor site. The tracer substance is taken up by the lymphatic vessels and transported to the sentinel lymph node(s), allowing the surgeon to locate and remove them.

The removed sentinel lymph node(s) are then examined under a microscope for the presence of cancer cells. If no cancer cells are found, it is unlikely that the cancer has spread to other lymph nodes or distant sites in the body. However, if cancer cells are present, further lymph node dissection and/or additional treatment may be necessary.

Sentinel lymph node biopsy is commonly used in the staging of melanoma, breast cancer, and some types of head and neck cancer.

Gastric emptying is the process by which the stomach empties its contents into the small intestine. In medical terms, it refers to the rate and amount of food that leaves the stomach and enters the duodenum, which is the first part of the small intestine. This process is regulated by several factors, including the volume and composition of the meal, hormonal signals, and neural mechanisms. Abnormalities in gastric emptying can lead to various gastrointestinal symptoms and disorders, such as gastroparesis, where the stomach's ability to empty food is delayed.

Organophosphorus compounds are a class of chemical substances that contain phosphorus bonded to organic compounds. They are used in various applications, including as plasticizers, flame retardants, pesticides (insecticides, herbicides, and nerve gases), and solvents. In medicine, they are also used in the treatment of certain conditions such as glaucoma. However, organophosphorus compounds can be toxic to humans and animals, particularly those that affect the nervous system by inhibiting acetylcholinesterase, an enzyme that breaks down the neurotransmitter acetylcholine. Exposure to these compounds can cause symptoms such as nausea, vomiting, muscle weakness, and in severe cases, respiratory failure and death.

In medical terms, the heart is a muscular organ located in the thoracic cavity that functions as a pump to circulate blood throughout the body. It's responsible for delivering oxygen and nutrients to the tissues and removing carbon dioxide and other wastes. The human heart is divided into four chambers: two atria on the top and two ventricles on the bottom. The right side of the heart receives deoxygenated blood from the body and pumps it to the lungs, while the left side receives oxygenated blood from the lungs and pumps it out to the rest of the body. The heart's rhythmic contractions and relaxations are regulated by a complex electrical conduction system.

Aerosols are defined in the medical field as suspensions of fine solid or liquid particles in a gas. In the context of public health and medicine, aerosols often refer to particles that can remain suspended in air for long periods of time and can be inhaled. They can contain various substances, such as viruses, bacteria, fungi, or chemicals, and can play a role in the transmission of respiratory infections or other health effects.

For example, when an infected person coughs or sneezes, they may produce respiratory droplets that can contain viruses like influenza or SARS-CoV-2 (the virus that causes COVID-19). Some of these droplets can evaporate quickly and leave behind smaller particles called aerosols, which can remain suspended in the air for hours and potentially be inhaled by others. This is one way that respiratory viruses can spread between people in close proximity to each other.

Aerosols can also be generated through medical procedures such as bronchoscopy, suctioning, or nebulizer treatments, which can produce aerosols containing bacteria, viruses, or other particles that may pose an infection risk to healthcare workers or other patients. Therefore, appropriate personal protective equipment (PPE) and airborne precautions are often necessary to reduce the risk of transmission in these settings.

"Technetium Tc 99m medronate". Drug Information Portal. U.S. National Library of Medicine. Portal: Medicine v t e (Articles with ... "TechneScan MDP Kit for the Preparation of Technetium Tc 99m Medronate Package Insert" (PDF). Mallinckrodt Medical. Retrieved 3 ... "Kit for the Preparation of Technetium Tc 99m Medronate for Injection" (PDF). Pharmalucence. Retrieved 3 March 2017. " ... FDA Label: MDP Multidose Utilipack KEGG Drug: D02029 "List of labelling kits for the preparation of a technetium-99m labelled ...
... technetium tc 99m lidofenin MeSH D02.691.825.750 - technetium tc 99m medronate MeSH D02.691.825.775 - technetium tc 99m ... technetium tc 99m dimercaptosuccinic acid MeSH D02.691.825.475 - technetium tc 99m disofenin MeSH D02.691.825.562 - technetium ... technetium tc 99m diethyl-iminodiacetic acid MeSH D02.241.081.583.450 - technetium tc 99m disofenin MeSH D02.241.081.583.900 - ... technetium tc 99m disofenin MeSH D02.491.485.900 - technetium tc 99m lidofenin MeSH D02.491.567.249 - imino furanoses MeSH ...
To evaluate the diagnostic value of technetium-99m d, l-hexamethylpropylene amine oxime (HMPAO) labelled leucocytes in ... Technetium Tc 99m Exametazime * Technetium Tc 99m Medronate Substances * Organotechnetium Compounds * Oximes ... Chronic osteomyelitis: diagnosis with technetium-99m-d, l-hexamethylpropylene amine oxime labelled leucocytes Eur J Nucl Med. ... To evaluate the diagnostic value of technetium-99m d, l-hexamethylpropylene amine oxime (HMPAO) labelled leucocytes in ...
"Technetium Tc 99m medronate". Drug Information Portal. U.S. National Library of Medicine. Portal: Medicine v t e (Articles with ... "TechneScan MDP Kit for the Preparation of Technetium Tc 99m Medronate Package Insert" (PDF). Mallinckrodt Medical. Retrieved 3 ... "Kit for the Preparation of Technetium Tc 99m Medronate for Injection" (PDF). Pharmalucence. Retrieved 3 March 2017. " ... FDA Label: MDP Multidose Utilipack KEGG Drug: D02029 "List of labelling kits for the preparation of a technetium-99m labelled ...
Technetium * Technetium Tc 99m Medronate Substances * Diphosphonates * Technetium * Technetium Tc 99m Medronate ...
... substances and experts consider that breastfeeding can be resumed immediately after a diagnostic test with Tc 99m medronate ( ... the technetium (99mTc) medronate solution obtained is used in bone scintigraphy. Between 0.01% (MDP blocked, with a T ½ of 5.2 ... The metastable Technetium 99 (99mTc) is a radioactive isotope that emits gamma radiation. Its half-life of radioactive decay is ... Technetium 99m methylene diphosphonate is also known as Technetium 99m Medronate (MDP). Here it is a list of alternative known ...
... www.drugs.com/mmx/technetium-tc-99m-medronate.html.. *Technetium Tc 99m sulfur colloid side effects [cited 2011 Apr 6]. In: ... Technetium* or Tc-99 or Tc99 or Tc-99m or Tc99m or 99mTc or 99m-Tc).tw,nm.. ... Technetium Tc 99m medronate (systemic). 1994 Nov 5 [cited 2011 Apr 6]. In: Drugs.com [Internet]. Auckland (NZ): Drugs.com; ... 99mTc-MDP = technetium-99m methylene diphosphonate; AUC = area under the curve; AVN = avascular necrosis; BS = bone scanning; ...
Technetium Tc 99m Medronate * 3-Iodobenzylguanidine Explore _. Co-Authors (6) People in Profiles who have published with this ...
Technetium Tc 99m Medronate Identity. Digital Object Identifier (DOI) * 10.1097/00003072-199408000-00024 ...
Technetium Tc 99m Medronate Medicine & Life Sciences 100% * Radionuclide Imaging Medicine & Life Sciences 68% ... Normal standards of technetium-99m methylene diphosphonate (99mTc-MDP) uptake in the jaws of adults and growing children have ... N2 - Normal standards of technetium-99m methylene diphosphonate (99mTc-MDP) uptake in the jaws of adults and growing children ... AB - Normal standards of technetium-99m methylene diphosphonate (99mTc-MDP) uptake in the jaws of adults and growing children ...
Technetium Tc 99m Medronate. A gamma-emitting radionuclide imaging agent used primarily in skeletal scintigraphy. Because of ... Lumbar VertebraeKnee JointUltrasonographyComputer Storage DevicesAnthracosisPatient PositioningTechnetium Tc 99m Medronate ...
technetium Tc 99m mebrofenin 8% * Technetium Tc 99m Medronate 8% * Single-Photon Emission-Computed Tomography 8% ...
Technetium Tc 99m Medronate 47% 7 Scopus citations * 2018 18F-FDG PET/CT and MRI features of myxoid liposarcomas and ...
Technetium Tc 99m Medronate Medicine & Life Sciences 100% * Buttocks Medicine & Life Sciences 43% ... Increased Tc-99m MDP Accumulation in Soft Tissue Caused by Bicycle Riding. / Kung, Justin W.; Yu, Jian Q.; Lee, Bruce et al. In ... Increased Tc-99m MDP Accumulation in Soft Tissue Caused by Bicycle Riding. In: Clinical nuclear medicine. 2004 ; Vol. 29, No. 4 ... Kung JW, Yu JQ, Lee B, Alavi A, Zhuang H. Increased Tc-99m MDP Accumulation in Soft Tissue Caused by Bicycle Riding. Clinical ...
Technetium tc - 99m medronate appears unsuitable to be better tolerated than epirizole 6, 7. In such circumstances bismuth ...
Technetium Tc-99m Medronate is a radiopharmaceutical containing methylene diphosphonate (medronate; MDP) complexed with the ... Technetium Tc 99m Albumin Aggregated Injection Technetium-99m (99m Tc) is a metastable nuclear isomer of technetium-99 (itself ... 99m Tc-labeled Isoniazid and 99m Tc-Labeled Ethambutol 99m Tc-INH and 99m Tc-EMB has been successfully used for the diagnosis ... Information in this record refers to the use of technetium Tc 99m bicisate (Tc 99m ethylcysteinate dimer; Tc 99m ECD) as a ...
D2.241.81.337.759.500.725 Technetium Tc 99m Medronate D2.705.206.885 D2.705.429.500.885 Technetium Tc 99m Pentetate D2.241. ... Z1.639.100.680 Technetium Tc 99m Dimercaptosuccinic Acid D2.241.81.337.820.525.725 ...
D2.241.81.337.759.500.725 Technetium Tc 99m Medronate D2.705.206.885 D2.705.429.500.885 Technetium Tc 99m Pentetate D2.241. ... Z1.639.100.680 Technetium Tc 99m Dimercaptosuccinic Acid D2.241.81.337.820.525.725 ...
D2.241.81.337.759.500.725 Technetium Tc 99m Medronate D2.705.206.885 D2.705.429.500.885 Technetium Tc 99m Pentetate D2.241. ... Z1.639.100.680 Technetium Tc 99m Dimercaptosuccinic Acid D2.241.81.337.820.525.725 ...
D2.241.81.337.759.500.725 Technetium Tc 99m Medronate D2.705.206.885 D2.705.429.500.885 Technetium Tc 99m Pentetate D2.241. ... Z1.639.100.680 Technetium Tc 99m Dimercaptosuccinic Acid D2.241.81.337.820.525.725 ...
D1.632.825.562 Technetium Tc 99m Lidofenin D1.632.825.710 Technetium Tc 99m Medronate D1.632.825.750 Technetium Tc 99m ... D1.632.825.445 Technetium Tc 99m Dimercaptosuccinic Acid D1.632.825.468 Technetium Tc 99m Disofenin D1.632.825.475 Technetium ... D1.632.825.775 Technetium Tc 99m Pentetate D1.632.825.875 Technetium Tc 99m Sestamibi D1.632.825.937 Technology, Medical H2.10. ... D4.345.349.810 Technetium Tc 99m Aggregated Albumin D1.632.825.375 Technetium Tc 99m Diethyl-iminodiacetic Acid ...
D1.632.825.562 Technetium Tc 99m Lidofenin D1.632.825.710 Technetium Tc 99m Medronate D1.632.825.750 Technetium Tc 99m ... D1.632.825.445 Technetium Tc 99m Dimercaptosuccinic Acid D1.632.825.468 Technetium Tc 99m Disofenin D1.632.825.475 Technetium ... D1.632.825.775 Technetium Tc 99m Pentetate D1.632.825.875 Technetium Tc 99m Sestamibi D1.632.825.937 Technology, Medical H2.10. ... D4.345.349.810 Technetium Tc 99m Aggregated Albumin D1.632.825.375 Technetium Tc 99m Diethyl-iminodiacetic Acid ...
D1.632.825.562 Technetium Tc 99m Lidofenin D1.632.825.710 Technetium Tc 99m Medronate D1.632.825.750 Technetium Tc 99m ... D1.632.825.445 Technetium Tc 99m Dimercaptosuccinic Acid D1.632.825.468 Technetium Tc 99m Disofenin D1.632.825.475 Technetium ... D1.632.825.775 Technetium Tc 99m Pentetate D1.632.825.875 Technetium Tc 99m Sestamibi D1.632.825.937 Technology, Medical H2.10. ... D4.345.349.810 Technetium Tc 99m Aggregated Albumin D1.632.825.375 Technetium Tc 99m Diethyl-iminodiacetic Acid ...
D1.632.825.562 Technetium Tc 99m Lidofenin D1.632.825.710 Technetium Tc 99m Medronate D1.632.825.750 Technetium Tc 99m ... D1.632.825.445 Technetium Tc 99m Dimercaptosuccinic Acid D1.632.825.468 Technetium Tc 99m Disofenin D1.632.825.475 Technetium ... D1.632.825.775 Technetium Tc 99m Pentetate D1.632.825.875 Technetium Tc 99m Sestamibi D1.632.825.937 Technology, Medical H2.10. ... D4.345.349.810 Technetium Tc 99m Aggregated Albumin D1.632.825.375 Technetium Tc 99m Diethyl-iminodiacetic Acid ...
D1.632.825.562 Technetium Tc 99m Lidofenin D1.632.825.710 Technetium Tc 99m Medronate D1.632.825.750 Technetium Tc 99m ... D1.632.825.445 Technetium Tc 99m Dimercaptosuccinic Acid D1.632.825.468 Technetium Tc 99m Disofenin D1.632.825.475 Technetium ... D1.632.825.775 Technetium Tc 99m Pentetate D1.632.825.875 Technetium Tc 99m Sestamibi D1.632.825.937 Technology, Medical H2.10. ... D4.345.349.810 Technetium Tc 99m Aggregated Albumin D1.632.825.375 Technetium Tc 99m Diethyl-iminodiacetic Acid ...
Technetium Tc 99m Mebrofenin (Intravenous Route) * Technetium Tc 99m Medronate (Intravenous Route) ... Technetium Tc 99m Tilmanocept (Injection Route) * Technetium TC 99m TSC - Technetium TC 99m TSC, also known asTechnetium Tc 99m ... Technetium TC 99m TSC - Technetium TC 99m TSC, also known asTechnetium Tc 99m Sulfurcolloid (Injection Route, Route Not ... Technetium Tc 99m Sulfurcolloid (Injection Route, Route Not Applicable) * Technetium Tc 99m Sulfurcolloid (Oral Route, Route ...
Technetium Tc 99m Gluconate. *Technetium Tc 99m Mebrofenin. *Technetium Tc 99m Medronate ... Technetium Tc 99m Red Blood Cells. *Technetium Tc 99m Sestamibi. *Technetium Tc 99m Sulfur Colloid ... Technetium Tc 99m Tetrofosmin. *Technetium Tc 99m Tilmanocept. *Technetium Tc 99m White Blood Cells ... Technetium Tc 99m Glucoheptonate. *Technetium Tc 99m Albumin. *Technetium Tc 99m Albumin Aggregated ...
... radionuclear bone scanning with technetium-99m methylene diphosphonate (99mTc MDP) is often successful. A delay of several days ... The dose of 99mTc-medronate is usually 800 megabecquerels (MBq). Imaging is generally performed after a 4-5 hour delay to allow ... with CT chest without IV contrast or technetirum-99m (Tc-99m) bone scan whole body as complementary to the chest radiography. ... The bone-seeking 99mTc-labeled phosphonates are selectively distributed into the areas that surround healing rib fractures. ...
... radionuclear bone scanning with technetium-99m methylene diphosphonate (99mTc MDP) is often successful. A delay of several days ... The dose of99m Tc-medronate is usually 800 megabecquerels (MBq). Imaging is generally performed after a 4-5 hour delay to allow ... The bone-seeking99m Tc-labeled phosphonates are selectively distributed into the areas that surround healing rib fractures. ...
Technetium-99m Medronate (MDP-25): Bone Imaging and Osteogenesis Evaluation. *Technetium-99m Mertiatide: A Gold Standard ... Diagnostic Potential of Technetium-99m Macroaggregated Albumin (Tc-99m MAA) in Hepatobiliary Imaging ... Technetium-99m Oxidronate (Technescan HDP) for Bone Imaging. *Technetium-99m Pentetate in Diagnostic Imaging: A Closer Look at ... Technetium-99m Pyrophosphate (Technescan PYP) in Bone Imaging and Cardiac Imaging. *Technetium-99m Sestamibi in Cardiac ...
  • To evaluate the diagnostic value of technetium-99m d, l-hexamethylpropylene amine oxime (HMPAO) labelled leucocytes in combination with a 99mTc-methylene diphosphonate (MDP) bone scan in the detection of chronic osteomyelitis, we retrospectively reviewed 55 patients. (nih.gov)
  • The drug is a complex of medronic acid (MDP, methylene diphosphonate), the simplest bisphosphonate, with technetium-99m (99mTc), a radionuclide that emits gamma rays. (wikipedia.org)
  • Technetium 99m methylene diphosphonate and breastfeeding. (e-lactancia.org)
  • We do not have alternatives for Technetium 99m methylene diphosphonate since it is relatively safe. (e-lactancia.org)
  • Technetium 99m methylene diphosphonate is also known as Technetium 99m Medronate (MDP) . (e-lactancia.org)
  • Bone scanning (bone scintigraphy) using technetium-99m-labelled methylene diphosphonate ( 99m Tc-MDP). (cadth.ca)
  • Normal standards of technetium-99m methylene diphosphonate ( 99m Tc-MDP) uptake in the jaws of adults and growing children have previously been established. (nyu.edu)
  • Upon intravenous administration, skeletal uptake of technetium Tc 99m methylene diphosphonate occurs as a function of skeletal blood flow and … Supply of Technetium-99m (Tc-99m) is a just-in-time activity requiring continuous production in a complicated and aging supply chain that combines a mix of governmental and commercial entities. (netlify.app)
  • Technetium (99mTc) medronic acid is a pharmaceutical product used in nuclear medicine to localize bone metastases as well as other diseases that can alter the natural turn-over in the bone by bone scintigraphy. (wikipedia.org)
  • After radioactive labelling with sodium pertechnetate (99mTc) solution, the technetium (99mTc) medronate solution obtained is used in bone scintigraphy. (e-lactancia.org)
  • Tc-99m MDP bone scintigraphy has long been used to evaluate bone pathology. (johnshopkins.edu)
  • Technetium-99m diethylene triamine pentaacetic acid (Tc-99m DTPA) renal dynamic scintigraphy is a widely used imaging technique that evaluates renal function of patients with extrarenal abnormalities, but its clinical value in potentially offering us information on proliferation of liposarcoma has not yet been reported. (netlify.app)
  • As with nuclear bone imaging for other indications, the radioisotope-labelled MDP is injected intravenously, and there is increased uptake of 99m Tc where there is increased bone turnover or remodelling. (cadth.ca)
  • 99m Tc-MDP uptake was measured in the right and left condyle, ramus, and body. (nyu.edu)
  • The metastable Technetium 99 (99mTc) is a radioactive isotope that emits gamma radiation. (e-lactancia.org)
  • MDP) complexed with the gamma-emitting radionuclide technetium Tc 99m with radioisotopic activity and hydroxyapatite affinity. (netlify.app)
  • Therefore, sodium pertechnetate Tc 99m containing oxidants should not be employed. (netlify.app)
  • Technetium-99m is used in over 20 million diagnostic nuclear medical procedures every year, half of which are bone scans, and the other half are roughly divided between kidney, heart and lung scans. (netlify.app)
  • A radiograph of the chest is usually appropriate for suspected pathologic rib fracture, with CT chest without IV contrast or technetirum-99m (Tc-99m) bone scan whole body as complementary to the chest radiography. (medscape.com)
  • The main regulatory agencies which manage radioactive substances and experts consider that breastfeeding can be resumed immediately after a diagnostic test with Tc 99m medronate (ARSAC 2019 p51, USNRC 2016 Tabl U.3, ICRP 2008 p163, Stabin 2000). (e-lactancia.org)
  • Kit for the Preparation of Technetium Tc 99m Medronate for Injection" (PDF). (wikipedia.org)
  • This safety record is attributable to the very small fraction of the pulmonary vasculature that is occluded by the typical injection of Tc-MAA. (netlify.app)
  • Single-photon emission computer tomography (SPECT) is a more advanced imaging technique, again requiring a radioactive tracer ( 99m Tc-MDP) and a gamma camera. (cadth.ca)
  • a) The specific gamma ray constant for Tc 99m is 0.78 R/millicurie-hr at 1 cm. (netlify.app)
  • 99m Tc-labeled Isoniazid and 99m Tc-Labeled Ethambutol 99m Tc-INH and 99m Tc-EMB has been successfully used for the diagnosis of sensitive as well as resistant tuberculosis in patients. (netlify.app)
  • 155 99m Tc is widely used in nuclear medicine owing to its nearly ideal nuclear properties. (netlify.app)
  • No long term animal studies have been performed to evaluate carcinogenic potential or whether Technetium Tc 99m Mebrofenin may … 2011-10-21 Pertechnetate Tc 99m may affect fertility in males or females. (netlify.app)
  • For this report, magnetic resonance imaging (MRI) is considered to be the only alternative to 99m Tc-MDP. (cadth.ca)
  • Characteristics photon energy: 140 KeV physical half life: 6 hours biological half life: 2-3 hours normal distribution: lungs, Tc-99m MAG3 (mercaptoacetyltriglycine) is one of the technetium radiopharmaceuticals used in renal imaging. (netlify.app)
  • Technetium (Tc) methylene diphosphonate (MDP) has been the standard method for bone scintigraphy for three decades. (nih.gov)
  • The drug is a complex of medronic acid (MDP, methylene diphosphonate), the simplest bisphosphonate, with technetium-99m (99mTc), a radionuclide that emits gamma rays. (wikipedia.org)
  • Mechanisms leading to increased extraosseous Tcm MDP uptake include extracellular fluid expansion, enhanced regional vascularityImaging withm Tc-methylene diphosphonate (99m Tc-MDP) is the initial method of choice to detect skeletal metastases in cancer patients. (zajezdarna.cz)
  • Each patient underwent a preoperative technetium 99 methylene diphosphonate bone scan using single photon emission computed tomography. (tau.ac.il)
  • 17. Diffuse hepatic and splenic uptake of Tc-99m methylene diphosphonate on bone scintigraphy after intravenous administration of gadolinium-containing MRI contrast. (nih.gov)
  • 20. Idiopathic hepatic uptake of (99m)Tc methylene diphosphonate: a case report. (nih.gov)
  • Technetium (99mTc) medronic acid is a pharmaceutical product used in nuclear medicine to localize bone metastases as well as other diseases that can alter the natural turn-over in the bone by bone scintigraphy. (wikipedia.org)
  • Administration is by intravenous injection for diagnostic use, after reconstitution with oxidant-free sodium pertechnetate Tc99m injection. (nih.gov)
  • During the initial 24 hours following intravenous injection of technetium Tc99m medronate about 50% of each dose is retained in the skeleton, and about 50% of each dose is excreted into the bladder. (nih.gov)
  • Technetium Tc99m medronate injection may be used as a bone imaging agent to delineate areas of altered osteogenesis. (nih.gov)
  • Reports indicate impairment of brain scans using sodium pertechnetate Tc99m injection which have been preceded by a bone scan using an agent containing stannous ions. (nih.gov)
  • Alternately, a brain-imaging agent such as technetium Tc99m pentetate injection may be employed. (nih.gov)
  • However, after the sodium pertechnetate Tc99m injection is added, adequate shielding of the final preparation must be maintained. (nih.gov)
  • Contents of the vial are intended only for use in the preparation of technetium Tc99m medronate injection and are NOT to be administered directly to the patient. (nih.gov)
  • Technetium Tc99m medronate injection, as well as other radioactive drugs, must be handled with care. (nih.gov)
  • Once sodium pertechnetate Tc99m injection is added to the vial, appropriate safety measures should be used to minimize external radiation to clinical occupational personnel. (nih.gov)
  • Kit for the Preparation of Technetium Tc 99m Medronate for Injection" (PDF). (wikipedia.org)
  • A 3-phase Tc-99m MDP bone scan involves injection of the tracer, followed by imaging at 3 separate time points. (medscape.com)
  • For nursing mothers who work with Tc 99m substances in their workplace, there is no need to take any precautions other than those appropriate for general radiation protection. (nih.gov)
  • 1 ] With perchlorate blocking, the effective half-life of Tc 99m medronate averages 4.9 hours and 0.01% of an administered dose appears in breastmilk. (nih.gov)
  • 9. Is (99m)Tc-labelled pamidronate a better agent than (99m)Tc-medronate for bone imaging? (nih.gov)
  • Technetiumm (99m Tc) is a metastable nuclear isomer of technetium (itself an isotope of technetium), symbolized asm Tc, that is used in tens of millions of medical Missing: mdp· γ-Tilmanocept ((99m)Tc-labeled-tilmanocept or [(99m)Tc]-tilmanocept) is the first mannose-containing, receptor-directed, radiolabeled tracer for the highly sensitive imaging of sentinel lymph nodes in solid tumor staging. (zajezdarna.cz)
  • Technetium Tc99m decays by isomeric transition with a physical half-life of 6.02 hours. (nih.gov)
  • A whole-body Tc-99m MDP bone scan is the most common technique used. (medscape.com)
  • Tc-99m MDP whole body bone scan showing typical anterior and posterior planar views. (medscape.com)
  • A radiograph of the chest is usually appropriate for suspected pathologic rib fracture, with CT chest without IV contrast or technetirum-99m (Tc-99m) bone scan whole body as complementary to the chest radiography. (medscape.com)
  • 1] The International Commission on Radiological Protection also recommends that breastfeeding need not be interrupted after administration technetium Tc 99m medronate. (nih.gov)
  • The precise structure of stannous technetium Tc99m medronate complex is unknown at this time. (nih.gov)
  • 10. Comparison of Tc-99m HIG and three-phase Tc-99m MDP bone scintigraphy for evaluating the efficacy of Yttrium-90 silicate radionuclide synovectomy. (nih.gov)