Pathological processes involving any of the BLOOD VESSELS feeding the SPINAL CORD, such as the anterior and paired posterior spinal arteries or their many branches. Disease processes may include ATHEROSCLEROSIS; EMBOLISM; and ARTERIOVENOUS MALFORMATIONS leading to ISCHEMIA or HEMORRHAGE into the spinal cord (hematomyelia).
A cylindrical column of tissue that lies within the vertebral canal. It is composed of WHITE MATTER and GRAY MATTER.
Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.
Pathologic conditions which feature SPINAL CORD damage or dysfunction, including disorders involving the meninges and perimeningeal spaces surrounding the spinal cord. Traumatic injuries, vascular diseases, infections, and inflammatory/autoimmune processes may affect the spinal cord.
Acute and chronic conditions characterized by external mechanical compression of the SPINAL CORD due to extramedullary neoplasm; EPIDURAL ABSCESS; SPINAL FRACTURES; bony deformities of the vertebral bodies; and other conditions. Clinical manifestations vary with the anatomic site of the lesion and may include localized pain, weakness, sensory loss, incontinence, and impotence.
Benign and malignant neoplasms which occur within the substance of the spinal cord (intramedullary neoplasms) or in the space between the dura and spinal cord (intradural extramedullary neoplasms). The majority of intramedullary spinal tumors are primary CNS neoplasms including ASTROCYTOMA; EPENDYMOMA; and LIPOMA. Intramedullary neoplasms are often associated with SYRINGOMYELIA. The most frequent histologic types of intradural-extramedullary tumors are MENINGIOMA and NEUROFIBROMA.
Pathological processes involving any one of the BLOOD VESSELS in the vasculature outside the HEART.

Peripheral spinal cord hypointensity on T2-weighted MR images: a reliable imaging sign of venous hypertensive myelopathy. (1/17)

BACKGROUND AND PURPOSE: MR findings reported in conjunction with spinal dural arteriovenous fistula (SDAVF) include cord swelling, increased T2 signal within the spinal cord, and parenchymal enhancement, each of which is nonspecific. Enlarged vessels on the cord surface, the most specific MR finding, is noted in only half of SDAVF patients. Nevertheless, we have frequently observed MR peripheral hypointensity of the spinal cord in SDAVF on T2-weighted images, which is not characteristic of nonvascular or nonhemorrhagic causes of myelopathy and which has not been described in association with SDAVF. We hypothesized that peripheral cord hypointensity might reliably suggest the diagnosis of SDAVF or other causes of venous hypertensive myelopathy. METHODS: We reviewed the MR findings in 11 consecutive cases of angiographically confirmed symptomatic SDAVF and in four cases of intracranial dural arteriovenous fistula with spinal drainage, a lesion that also causes spinal cord deficits mediated by venous hypertensive myelopathy. RESULTS: In each case, T2 hypointensity involving the cord periphery was present. This sign has not been previously described in association with either SDAVF or other causes of venous hypertensive myelopathy. It appears, however, to be a relatively constant imaging feature of SDAVF. CONCLUSION: In the absence of spinal hemorrhage, T2 hypointensity involving the periphery of the spinal cord suggests venous hypertensive myelopathy as a cause of spinal cord dysfunction.  (+info)

Neurovascular complications of marfan syndrome: a retrospective, hospital-based study. (2/17)

BACKGROUND AND PURPOSE: Small case series have associated Marfan syndrome with cerebral and spinal ischemia or hemorrhage. However, there has been no investigation of the frequency and etiology of neurovascular disorders in a large series of Marfan patients. METHODS: We conducted a retrospective, hospital-based study of all Marfan syndrome patients seen in an 8-year period. Records were reviewed in detail, and clinical characteristics of those with and without a neurovascular diagnosis compared. RESULTS: Of 513 patients, 18 (3.5%) had a neurovascular diagnosis, as follows: transient ischemic attack (11), cerebral infarction (2), spinal cord infarction (2), subdural hematoma (2), and spinal subarachnoid hemorrhage (1). A cardioembolic source was identified in 12 of 13 patients with cerebral ischemia, as follows: prosthetic heart valves (9), mitral valve prolapse (2), and atrial fibrillation (1). Chronic anticoagulant therapy was a likely cause in 2 of 3 patients with hemorrhagic events. Compared with other Marfan syndrome patients, those with neurovascular events were older (39.6 versus 31.7 years, P=0.04) and more likely to be in atrial fibrillation (22.2% versus 3.2%, P=<0.01), to have prosthetic heart valves (61.1% versus 7.7%, P=0.001), and to be taking anticoagulant therapy (72.2% versus 16.1%, P<0.001). Aortic disease, a putative factor in the etiology of neurovascular complications, was present in equal measure in Marfan patients with and without neurovascular complications (78% versus 65%, P=NS). CONCLUSIONS: Neurovascular complications of Marfan syndrome are rare during 8 years of follow-up, and generally are ischemic in nature. A high-risk cardiac source was identified in the majority. A significant association with vascular dissection was not established.  (+info)

Spinal tanycytic ependymoma with hematomyelia--case report--. (3/17)

A 58-year-old man presented with an extremely rare case of "pure type" spinal tanycytic ependymoma associated with hematomyelia manifesting as sensory disturbance of the bilateral hands and weakness of the right arm. Magnetic resonance imaging demonstrated a tumor in the spinal cord from C-2 to C-4 levels. The soft gelatinous tumor was subtotally resected and the adjacent chronic liquid hematoma was aspirated. The immunohistochemical and ultrastructural findings indicated a diagnosis of tanycytic ependymoma.  (+info)

Transient traumatic spinal venous hypertensive myelopathy. (4/17)

We present a case of a reversible spinal venous hypertensive myelopathy that occurred following a traumatic mediastinal hematoma. The mediastinal hematoma caused compression of the brachiocephalic vein, resulting in elevation of the venous pressures that ultimately resulted in dilation of the epidural venous plexus and spinal cord edema. The secondary neurologic deficits were the culmination of venous outflow obstruction at the level of the spinal cord that resolved on the resolution of the mediastinal hematoma.  (+info)

Usefulness of combined electrophysiological examinations for detection of neural dysfunction in cats with lumbar hematomyelia. (5/17)

We conducted combined electrophysiological examinations including F-wave, motor nerve conduction velocity (MNCV), spinal cord-evoked potential (SCEP), and needle electromyography (EMG) in two cats involved in traffic accidents that consequently developed hind limb paralysis caused by lumbar hematomyelia. F-wave could no longer be elicited within 3 days after the accident, and the MNCV and compound muscle action potential (CMAP) amplitude decreased in a time-dependent manner, with CMAP no longer being evoked after 7 or 8 days. EMG showed abnormalities such as fibrillation and positive sharp waves after 6 to 8 days. These results suggest that such combined electrophysiological examinations may provide objective, quantitative data for motor nerve dysfunction in cats with lumbar hematomyelia.  (+info)

Spinal arteriovenous shunts presenting as intracranial subarachnoid haemorrhage. (6/17)

BACKGROUND: In approximately 5% of patients with intracranial subarachnoid haemorrhage (SAH), the cause is another than a ruptured aneurysm or perimesencephalic haemorrhage. One of these causes is a spinal arteriovenous shunt (SAVS). The aim of this study was to investigate the characteristics of patients with SAVS who present with intracranial SAH without symptoms and signs suggesting a spinal cause. METHODS: We systematically reviewed the literature and searched the SAH database of the University Medical Center Utrecht, The Netherlands, for patients with SAVS presenting with intracranial SAH and studied the characteristics of patients with SAVS whose clinical presentation mimicked intracranial SAH caused by rupture of a saccular aneurysm. RESULTS: Thirty-five patients were identified after a review of the literature. In our SAH database, comprising 2142 patients included in the period 1985-2004, we found one patient (0.05%, 95 % CI 0.006- 0.3%). SAH due to SAVS occurred at any age (4-72 years). The SAVS was located at the craniocervical junction in 14 patients, at the cervical level in 11, and at the thoracolumbar level in the remaining 11 patients. The majority of patients (n = 26, 72%) had no disabling deficits at discharge or follow-up. CONCLUSION: Rupture of a SAVS presenting as intracranial SAH is rare and can occur at any age. The SAVS can be located not only at the craniocervical junction or cervical level but also in the thoracolumbar region. Most patients with SAVS presenting as intracranial SAH have a good recovery.  (+info)

Hematomyelia caused by ruptured intramedullary spinal artery aneurysm associated with extramedullary spinal arteriovenous fistula--case report. (7/17)

A 53-year-old woman presented with a ruptured intramedullary aneurysmal dilatation fed by the anterior spinal artery associated with an arteriovenous malformation located in the ventral cervical spinal cord. She developed tetraparesis and respiratory dysfunction. The neurological deterioration was caused by hematomyelia due to the ruptured aneurysmal dilatation and progression of edema in the upper cervical spinal cord due to venous hypertension associated with additional hematoma in the medulla oblongata. Endovascular embolization of both C-1 and C-2 radicular arteries was performed with Guglielmi detachable coils, but components fed by small branches such as the radiculo-pial artery were not obliterated. Surgery was performed for extirpation of the arteriovenous malformation and cervical intramedullary hematoma, and excision of the aneurysmal dilatation through a transcondylar approach combined with vertebral artery transposition. Postoperatively, she overcame several complications such as pneumonia and endocarditis, and had only moderate weakness of the right upper and lower limbs. This case indicates that surgical intervention for high cervical intramedullary lesion may be very effective.  (+info)

Intramedullary cavernoma presenting with hematomyelia: report of two girls. (8/17)

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Spinal cord vascular diseases refer to a group of disorders that affect the blood vessels of the spinal cord. These conditions can result in insufficient blood supply to the spinal cord tissue, leading to ischemia (lack of oxygen) and infarction (tissue death). There are several types of spinal cord vascular diseases, including:

1. Spinal Cord Infarction: This is a rare condition that occurs due to the blockage or narrowing of the arteries supplying blood to the spinal cord. It can result in sudden onset of weakness, numbness, or paralysis in parts of the body served by the affected spinal cord region.
2. Spinal Cord Aneurysm: This is a localized dilation or bulging of a weakened area in the wall of a blood vessel that supplies the spinal cord. If an aneurysm ruptures, it can cause bleeding into the spinal cord tissue, leading to neurological deficits.
3. Spinal Cord Arteriovenous Malformations (AVMs): These are abnormal connections between the arteries and veins in the spinal cord. AVMs can lead to bleeding, ischemia, or both, resulting in various neurological symptoms.
4. Spinal Cord Dural Arteriovenous Fistulas (dAVFs): These are abnormal communications between the spinal artery and a vein located outside the dura mater (the protective covering of the spinal cord). dAVFs can cause venous congestion, leading to ischemia and neurological dysfunction.
5. Spinal Cord Vasculitis: This is an inflammation of the blood vessels in the spinal cord, which can lead to narrowing or blockage of the affected vessels. It can result in various neurological symptoms, such as weakness, numbness, or pain.

Treatment for spinal cord vascular diseases depends on the specific condition and its severity. Treatment options may include medications, surgery, endovascular procedures, or a combination of these approaches.

The spinal cord is a major part of the nervous system, extending from the brainstem and continuing down to the lower back. It is a slender, tubular bundle of nerve fibers (axons) and support cells (glial cells) that carries signals between the brain and the rest of the body. The spinal cord primarily serves as a conduit for motor information, which travels from the brain to the muscles, and sensory information, which travels from the body to the brain. It also contains neurons that can independently process and respond to information within the spinal cord without direct input from the brain.

The spinal cord is protected by the bony vertebral column (spine) and is divided into 31 segments: 8 cervical, 12 thoracic, 5 lumbar, 5 sacral, and 1 coccygeal. Each segment corresponds to a specific region of the body and gives rise to pairs of spinal nerves that exit through the intervertebral foramina at each level.

The spinal cord is responsible for several vital functions, including:

1. Reflexes: Simple reflex actions, such as the withdrawal reflex when touching a hot surface, are mediated by the spinal cord without involving the brain.
2. Muscle control: The spinal cord carries motor signals from the brain to the muscles, enabling voluntary movement and muscle tone regulation.
3. Sensory perception: The spinal cord transmits sensory information, such as touch, temperature, pain, and vibration, from the body to the brain for processing and awareness.
4. Autonomic functions: The sympathetic and parasympathetic divisions of the autonomic nervous system originate in the thoracolumbar and sacral regions of the spinal cord, respectively, controlling involuntary physiological responses like heart rate, blood pressure, digestion, and respiration.

Damage to the spinal cord can result in various degrees of paralysis or loss of sensation below the level of injury, depending on the severity and location of the damage.

Spinal cord injuries (SCI) refer to damage to the spinal cord that results in a loss of function, such as mobility or feeling. This injury can be caused by direct trauma to the spine or by indirect damage resulting from disease or degeneration of surrounding bones, tissues, or blood vessels. The location and severity of the injury on the spinal cord will determine which parts of the body are affected and to what extent.

The effects of SCI can range from mild sensory changes to severe paralysis, including loss of motor function, autonomic dysfunction, and possible changes in sensation, strength, and reflexes below the level of injury. These injuries are typically classified as complete or incomplete, depending on whether there is any remaining function below the level of injury.

Immediate medical attention is crucial for spinal cord injuries to prevent further damage and improve the chances of recovery. Treatment usually involves immobilization of the spine, medications to reduce swelling and pressure, surgery to stabilize the spine, and rehabilitation to help regain lost function. Despite advances in treatment, SCI can have a significant impact on a person's quality of life and ability to perform daily activities.

Vascular diseases are medical conditions that affect the circulatory system, specifically the blood vessels (arteries, veins, and capillaries). These diseases can include conditions such as:

1. Atherosclerosis: The buildup of fats, cholesterol, and other substances in and on the walls of the arteries, which can restrict blood flow.
2. Peripheral Artery Disease (PAD): A condition caused by atherosclerosis where there is narrowing or blockage of the peripheral arteries, most commonly in the legs. This can lead to pain, numbness, and cramping.
3. Coronary Artery Disease (CAD): Atherosclerosis of the coronary arteries that supply blood to the heart muscle. This can lead to chest pain, shortness of breath, or a heart attack.
4. Carotid Artery Disease: Atherosclerosis of the carotid arteries in the neck that supply blood to the brain. This can increase the risk of stroke.
5. Cerebrovascular Disease: Conditions that affect blood flow to the brain, including stroke and transient ischemic attack (TIA or "mini-stroke").
6. Aneurysm: A weakened area in the wall of a blood vessel that causes it to bulge outward and potentially rupture.
7. Deep Vein Thrombosis (DVT): A blood clot that forms in the deep veins, usually in the legs, which can cause pain, swelling, and increased risk of pulmonary embolism if the clot travels to the lungs.
8. Varicose Veins: Swollen, twisted, and often painful veins that have filled with an abnormal collection of blood, usually appearing in the legs.
9. Vasculitis: Inflammation of the blood vessels, which can cause damage and narrowing, leading to reduced blood flow.
10. Raynaud's Phenomenon: A condition where the small arteries that supply blood to the skin become narrowed, causing decreased blood flow, typically in response to cold temperatures or stress.

These are just a few examples of vascular conditions that fall under the umbrella term "cerebrovascular disease." Early diagnosis and treatment can significantly improve outcomes for many of these conditions.

Spinal cord diseases refer to a group of conditions that affect the spinal cord, which is a part of the central nervous system responsible for transmitting messages between the brain and the rest of the body. These diseases can cause damage to the spinal cord, leading to various symptoms such as muscle weakness, numbness, pain, bladder and bowel dysfunction, and difficulty with movement and coordination.

Spinal cord diseases can be congenital or acquired, and they can result from a variety of causes, including infections, injuries, tumors, degenerative conditions, autoimmune disorders, and genetic factors. Some examples of spinal cord diseases include multiple sclerosis, spina bifida, spinal cord injury, herniated discs, spinal stenosis, and motor neuron diseases such as amyotrophic lateral sclerosis (ALS).

The treatment for spinal cord diseases varies depending on the underlying cause and severity of the condition. Treatment options may include medication, physical therapy, surgery, and rehabilitation. In some cases, the damage to the spinal cord may be irreversible, leading to permanent disability or paralysis.

Spinal cord compression is a medical condition that refers to the narrowing of the spinal canal, which puts pressure on the spinal cord and the nerves that branch out from it. This can occur due to various reasons such as degenerative changes in the spine, herniated discs, bone spurs, tumors, or fractures. The compression can lead to a range of symptoms including pain, numbness, tingling, weakness, or loss of bladder and bowel control. In severe cases, it can cause paralysis. Treatment options depend on the underlying cause and may include physical therapy, medication, surgery, or radiation therapy.

Spinal cord neoplasms refer to abnormal growths or tumors within the spinal cord. These can be benign (non-cancerous) or malignant (cancerous). They originate from the cells within the spinal cord itself (primary tumors), or they may spread to the spinal cord from other parts of the body (metastatic tumors). Spinal cord neoplasms can cause various symptoms depending on their location and size, including back pain, neurological deficits, and even paralysis. Treatment options include surgery, radiation therapy, and chemotherapy.

Peripheral Vascular Diseases (PVD) refer to a group of medical conditions that affect the blood vessels outside of the heart and brain. These diseases are characterized by a narrowing or blockage of the peripheral arteries, which can lead to reduced blood flow to the limbs, particularly the legs.

The primary cause of PVD is atherosclerosis, a buildup of fats, cholesterol, and other substances in and on the walls of the arteries, forming plaques that restrict blood flow. Other risk factors include smoking, diabetes, hypertension, high cholesterol levels, and a family history of vascular disease.

Symptoms of PVD can vary depending on the severity of the condition but may include leg pain or cramping during exercise (claudication), numbness or tingling in the legs, coldness or discoloration of the feet, sores or wounds that heal slowly or not at all, and in severe cases, gangrene.

PVD can increase the risk of heart attack and stroke, so it is essential to diagnose and treat the condition as early as possible. Treatment options include lifestyle changes such as quitting smoking, exercising regularly, and maintaining a healthy diet, medications to control symptoms and reduce the risk of complications, and surgical procedures such as angioplasty or bypass surgery to restore blood flow.

Erdek MA, Staats PS (2003). "Spinal cord stimulation for angina pectoris and peripheral vascular disease". Anesthesiol Clin ...
SCI may occur in intervertebral disc disease, and spinal cord vascular disease. Spontaneous bleeding can occur within or ... A spinal cord injury (SCI) is damage to the spinal cord that causes temporary or permanent changes in its function. Symptoms ... Anterior spinal artery syndrome also known as anterior spinal cord syndrome, due to damage to the front portion of the spinal ... At each level of the spinal column, spinal nerves branch off from either side of the spinal cord and exit between a pair of ...
Acton, Ashton (2012-12-26). Spinal Cord Vascular Diseases-Advances in Research and Treatment: 2012 Edition: ScholarlyPaper. ... such as the anterior spinal artery, can become kinked, depriving the spinal cord of oxygen. Although the condition derives its ... Surfer's myelopathy is a rare, nontraumatic spinal cord injury caused by hyperextension of the back injury and resulting in ... Rehabilitation in spinal cord injury Hawkes, Christopher H.; Sethi, Kapil D.; Swift, Thomas R. (2016-03-29). Instant ...
Vuong, Shawn M.; Jeong, William J.; Morales, Humberto; Abruzzo, Todd A. (2016-10-01). "Vascular Diseases of the Spinal Cord: ... Unlike anterior spinal cord stroke, motor functions are not handicapped in posterior spinal cord stroke. In central spinal cord ... Spinal cord stroke is a rare type of stroke with compromised blood flow to any region of spinal cord owing to occlusion or ... It is possible that spinal cord ischaemia patients have a full recovery. Although the mortality rate after spinal cord ...
As for the spinal cord involvement, pyramidal signs in the limbs, sensory level dysfunction, and, commonly, sphincter ... Because Non-parenchymal NBD targets vascular structures, the symptoms arise in the same area. The main clinical characteristic ... A related disorder to Neuro-Behçet's disease is neuro-Sweet disease. Sweet disease (or acute febrile neutrophilic dermatosis) ... The target areas of parenchymal NBD include brainstem, spinal cord, and cerebral regions. Sometimes it is hard to determine the ...
It may present as stroke or spinal cord infarct. Signs and symptoms vary with vascular territory involved. The middle cerebral ... Lumbar puncture ("spinal tap") is used to acquire CSF. The Venereal Disease Research Laboratory test of the CSF is the ... Tabes dorsalis thought to be due to irreversible degeneration of nerve fibers in posterior columns of the spinal cord involving ... The extension of cellular immune response to the brainstem and spinal cord causes inflammation and necrosis of small meningeal ...
Petrovici authored Vascular Diseases of the Brain and of the Spinal Cord in 1965. In 1969, he emigrated to Germany and began ... Petrovici published numerous papers on cerebrovascular disease, seizure disorders, therapy of the malignant brain tumours, ...
Diseases such as cardiovascular disease, multiple sclerosis, kidney failure, vascular disease, and spinal cord injury can cause ... ED from vascular disease is seen mainly amongst older individuals who have atherosclerosis. Vascular disease is common in ... as in sexual dysfunction after spinal cord injuries). Diseases such as diabetic neuropathy, multiple sclerosis, tumors, and, ... peripheral vascular disease, or hypertension. Any time blood flow to the penis is impaired, ED can occur. Drugs are also a ...
... and the spinal cord. "ADan amyloidosis - About the Disease". rarediseases.info.nih.gov. Retrieved 22 July 2023. Paul, Robert H ... ISBN 978-0-19-973196-1. Wahlund, Lars-Olof; Erkinjuntti, Timo; Gauthier, Serge (2009-02-12). Vascular Cognitive Impairment in ... ADan causes amyloid angiopathy in the cerebrum, choroid plexus, cerebellum, spinal cord, and retinas. Mutations in Cystatin C ... Differential diagnosis includes Begger syndrome and Refsum disease. Most people with this condition die when they reach their ...
Sometimes, these tumors occur in other sites such as the spinal cord and retina. They may be associated with other diseases ... Hemangioblastomas, or haemangioblastomas, are vascular tumors of the central nervous system that originate from the vascular ... brainstem or spinal cord. They are classed as grade I tumors under the World Health Organization's classification system. ... the brain stem or the spinal cord. Micrograph of cerebellar hemangioblastoma. HPS stain. Micrograph of cerebellar ...
... (vascular disease of the spinal cord) refers to an abnormality of the spinal cord in regard to its blood ... "Vascular myelopathies-vascular malformations of the spinal cord: presentation and endovascular surgical management". Semin ... The anterior spinal artery has a less efficient supply of blood and is therefore more susceptible to vascular disease. Whilst ... Both the posterior and anterior spinal arteries run the entire length of the spinal cord and receive anastomotic (conjoined) ...
CD34+ hematopoietic Stem Cells have been clinically applied to treat various diseases including spinal cord injury, liver ... cirrhosis and Peripheral Vascular disease. Research has shown that CD34+ hematopoietic Stem Cells are relatively more numerous ... 5 July 2012). "Index of CD34+ Cells and Mononuclear Cells in the Bone Marrow of Spinal Cord Injury Patients of Different Age ... 2010). "Multiple injections of in vitro expanded autologous bone marrow stem cells for cervical level spinal cord injury - a ...
Injection of CD34+ hematopoietic stem cells has been clinically applied to treat various diseases including spinal cord injury ... liver cirrhosis and peripheral vascular disease. CD34 has been shown to interact with CRKL. It also interacts with L-selectin, ... "Autologous Multiple Injections of in Vitro Expanded Autologous Bone Marrow Stem Cells For Cervical Level Spinal Cord Injury - A ... Cells expressing CD34 (CD34+ cell) are normally found in the umbilical cord and bone marrow as haematopoietic cells, or in ...
Disease that is vascular in nature is known as vascular myelopathy. In Asian populations, spinal cord compression often occurs ... spinal stenosis) ultimately causing compression of the spinal cord. When due to trauma, myelopathy is known as (acute) spinal ... The best way to visualize the spinal cord is magnetic resonance imaging (MRI). Apart from T1 and T2 MRI images, which are ... Myelopathy describes any neurologic deficit related to the spinal cord. The most common form of myelopathy in humans, cervical ...
... but patients can have both vascular disease in the legs and spinal stenosis.[citation needed] Among people with lower-extremity ... Narrowing of spinal structures in the spinal cord such as the central canal, the lateral recesses, or the intervertebral ... This occurs as the spinal nerves or spinal cord become increasingly trapped in a smaller space within the canal. Determining ... in which case it is known as cervical spinal stenosis or thoracic spinal stenosis. Lumbar spinal stenosis can cause pain in the ...
... of the variable vascularity of the spinal cord was an important contribution to the development of modern clinical vascular ... He is known for Mikulicz' disease, Heineke-Mikulicz strictureplasty, Mikulicz's drain. Aleksander Możajski, Polish-Russian ... the discoverer of the variable vascularity of the spinal cord". Ann. Thorac. Surg. 80 (5): 1971-5. doi:10.1016/j.athoracsur. ... established the localization principle of long fibers in the spinal cord (1893), and with Sterling published an early paper ( ...
... of this protein presents a great potential for the treatment of auto-immune mediated demyelinating diseases and spinal cord ... Moreover, vascular leakage, a major complication following stroke, was reduced following anti-Nogo-A antibody treatment. ... Schweigreiter R, Bandtlow CE (2006). "Nogo in the injured spinal cord". Journal of Neurotrauma. 23 (3-4): 384-96. doi:10.1089/ ... Solution structure of Nogo-40, a Nogo-66 receptor antagonist enhancing injured spinal cord regeneration". European Journal of ...
Other common causes of hypertensive crises are autonomic hyperactivity such as pheochromocytoma, collagen-vascular diseases, ... spinal cord disorders, glomerulonephritis, head trauma, neoplasias, preeclampsia and eclampsia, hyperthyroidism and ... of normal autoregulation and an abrupt rise in systemic vascular resistance are typical initial components of the disease ... As the left ventricle becomes unable to compensate for an acute rise in systemic vascular resistance, left ventricular failure ...
... vascular and hereditary diseases. Spinazzi M, Angelini C, Patrini C (May 2010). "Subacute sensory ataxia and optic neuropathy ... of sensory large fiber peripheral neuropathies and conditions causing dysfunction of the dorsal columns of the spinal cord due ... Sghirlanzoni A, Pareyson D, Lauria G (June 2005). "Sensory neuron diseases". Lancet Neurol. 4 (6): 349-61. doi:10.1016/S1474- ...
... disease 335.8 Other 335.9 Unspecified 336 Other diseases of spinal cord 336.0 Syringomyelia and syringobulbia 336.1 Vascular ... Myelopathy in other diseases classified elsewhere 336.8 Other myelopathy 336.9 Unspecified diseases of spinal cord 337 ... classified elsewhere 334.8 Other 334.9 Unspecified 335 Anterior horn cell disease 335.0 Werdnig-Hoffmann disease 335.1 Spinal ... Polyneuropathy in collagen vascular disease 357.2* Polyneuropathy in diabetes (250.5†) 357.3* Polyneuropathy in malignant ...
... mitochondria disease, and any disorder that has neural deterioration in the brain or spinal cord. While pathology has been ... Some of these divisions of neurosurgery are: Vascular neurosurgery includes clipping of aneurysms and performing carotid ... Spinal cord trauma Traumatic injuries of peripheral nerves Tumors of the spine, spinal cord and peripheral nerves Intracerebral ... Some indications for spine surgery include spinal cord compression resulting from trauma, arthritis of the spinal discs, or ...
... spinal cord injuries MeSH C10.228.854.770.500 - central cord syndrome MeSH C10.228.854.785 - spinal cord vascular diseases MeSH ... spinal cord compression MeSH C10.228.854.765 - spinal cord neoplasms MeSH C10.228.854.765.342 - epidural neoplasms MeSH C10.228 ... spinal cord ischemia MeSH C10.228.854.785.650.100 - anterior spinal artery syndrome MeSH C10.228.854.787 - spinocerebellar ... lewy body disease MeSH C10.228.140.079.862.500 - parkinson disease MeSH C10.228.140.079.862.800 - parkinson disease, secondary ...
Parkinson's disease, epilepsy, stroke, brain tumours, concussions, spinal cord injuries, neuro-ophthalmologic and other ocular ... spinal cord injuries, cerebral ischemia (stroke), vascular brain malformations, aneurysms, brain tumours and pain disorders. ... A. Lozano & S. Kennedy, 2003) Neural adult stem cell transplantation findings show promising results in repairing spinal cord ... nervous system as they develop treatments for neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease, ...
... peripheral vascular disease and angina. The general process for spinal cord stimulation involves a temporary trailing of ... Spinal cord stimulation is a form of invasive neuromodulation therapy in common use since the 1980s. Its principal use is as a ... All forms of spinal cord stimulation have been shown to have varying degrees of efficacy to address a variety of ... DBS therapy, unlike spinal cord stimulation, has a variety of central nervous system targets, depending on the target pathology ...
Urology diseases Vascular surgery "Årsredovisning och korta fakta". www.akademiska.se (in Swedish). Retrieved 2019-08-12. ... rehabilitation Prosthesis Rehabilitation of spinal cord injuries Surgical treatment and radio therapy for cancer Thoracic ... hepatology Gynecological endocrinology and infertility Immune deficiency diseases Neuro Centre, neurology, neurophysiology ... Geriatrics Gastroenterology Haematology Hepatology Hospital Physics Immunology and Transfusion Medicine Infectious Diseases ...
... may refer to: Acute viral meningitis, inflammation of the protective membranes covering the brain and spinal cord, caused ... a fatal neurological disease ActionScript Virtual Machine, a component of Adobe Flash Player Adaptive Vehicle Make, a United ... by a viral infection Arteriovenous malformation, a congenital disorder of the veins and arteries that make up the vascular ...
... cerebral palsy and spinal cord injury though research is still preliminary. In trials studying the use of cerebrolysin after ... research indicate a possible improvement in cognitive function using cerebrolysin for vascular dementia and Alzheimer's disease ... a mixture of neurotrophic factors induces marked neuroprotection in spinal cord injury following intoxication of engineered ... Cui S, Chen N, Yang M, Guo J, Zhou M, Zhu C, He L (November 2019). "Cerebrolysin for vascular dementia". The Cochrane Database ...
"Adult spinal cord progenitor cells are repelled by netrin-1 in the embryonic and injured adult spinal cord". Proceedings of the ... This finding has implications in the future treatment of vascular disease in the placenta. In adults, netrin has been ... Mice with mutations in the netrin-1 gene were observed to be lacking in forebrain and spinal cord commissural axons. Netrin-1 ... Also, the migration of adult neural progenitor cell and adult spinal cord progenitor cells to the spine is netrin 1 dependent. ...
The activated motor neurons then transmit their signals, via action potential, to motor neurons in the spinal cord. However, ... breakdown resulting in vascular leakiness. The first major proposed cause of neuronal death in Parkinson's disease is the ... Disruption of the autophagy mechanism can lead to several different types of diseases like Parkinson's disease. Autophagy ... but is believed to be disrupted in Parkinson's disease and Alzheimer's disease. This then causes cells to stop growing and ...
... heart Intellectual disability Seizures Abnormal bone formation of many bones Progressive deterioration of brain and spinal cord ... The disease itself is extremely rare (less than 100 documented cases) only affecting 1:2,000,000, with most cases occurring in ... In the more severe forms (type 1), "patients have no vascular lesions, but have rapid psychomotor regression, severe and ... Fucosidosis is now considered to be a single disorder and "represents a disease spectrum with a wide variety of expression." ...
... and interwoven vascular structures that perfuse the spinal parenchyma. Spinal cord vascular malformations (arterial and venous ... represent a heterogenous group of blood vessel disorders that affect the spinal cord parenchyma either directly or indirectly. ... The spinal cord is composed of neuronal pathways, glial tissue, ... Vascular diseases of the spinal cord. Neurol Clin. 2013 Feb. 31 ... Spinal cord vascular shunts: spinal cord vascular malformations and dural arteriovenous fistulas. Neurosurg Focus. 2009 Jan. 26 ...
Erdek MA, Staats PS (2003). "Spinal cord stimulation for angina pectoris and peripheral vascular disease". Anesthesiol Clin ...
It most commonly is caused by trauma, vascular malformations, or bleeding diatheses and can be intramedullary, subarachnoid, ... Vascular Diseases of the Spinal Cord: Infarction, Hemorrhage, and Venous Congestive Myelopathy. Semin Ultrasound CT MR. 2016 ... Vascular supply and venous drainage of the spinal cord. The cross-sectional blood supply of the spinal cord can be divided into ... 1] Spinal cord hemorrhage is most commonly caused by trauma, vascular malformations, or bleeding diatheses. Spinal cord ...
Spinal Cord Diseases [C10.228.854]. *Spinal Cord Vascular Diseases [C10.228.854.785]. *Spinal Cord Ischemia [C10.228.854.785. ... Reduced blood flow to the spinal cord which is supplied by the anterior spinal artery and the paired posterior spinal arteries ... "Spinal Cord Ischemia" by people in Harvard Catalyst Profiles by year, and whether "Spinal Cord Ischemia" was a major or minor ... Preoperative Spinal Drain Placement is Associated with Reduced Risk of Spinal Cord Ischemia in Patients Undergoing Thoracic ...
Vascular Disease. Respiratory Diseases. Diseases Affecting the Brain. Spinal Cord Disorders. Diseases of the Autonomic and ... Endocrine Disease. Hematologic Disorders. Skin and Musculoskeletal Diseases. Infectious Diseases. Cancer. Diseases Related to ... Ischemic Heart Disease. Valvular Heart Disease. Congenital Heart Disease. Abnormalities of Cardiac Conduction and Cardiac ... Psychiatric Disease, Substance Abuse, and Drug Overdose. Pregnancy-Associated Diseases. Pediatric Diseases. Geriatric Disorders ...
... cervical cord involvement is rare. Findings include necrosis of the affected cord regions. ... malformation of the spinal cord predominantly affecting the lower thoracic and/or lumbosacral levels; ... Diseases & Conditions Epidural Hematoma * 2002248456-overviewProcedures. Procedures Vascular Malformations of the Spinal Cord ... Photomicrograph of the cervical spinal cord region showing a thickened subarachnoid vein with a thrombotic occlusion ( ...
Problems with the joints, (such as arthritis), bones (such as deformities), circulation (such as peripheral vascular disease), ... Problems with the joints, (such as arthritis), bones (such as deformities), circulation (such as peripheral vascular disease), ... Diseases or injuries to the nerves, muscles, brain, spinal cord, or inner ear can affect normal walking. ... Problems with the joints, (such as arthritis), bones (such as deformities), circulation (such as peripheral vascular disease), ...
Neoplastic Disease of the Spine and Spinal Cord *Spinal Trauma *Vascular Disorders of the Spine and Spinal Cord *Spinal ... Spine and Spinal Cord. *Congenital Anomalies of the Spine and Spinal Cord: Embryology and Malformations *Degenerative Disease ... Psychiatric Disease *MR Spectroscopy and the Biochemical Basis of Neurological Disease *Contrast Agents and Molecular MR. Index ... Normal Aging, Dementia, and Neurodegenerative Disease. Volume Two. Skull Base. *The Skull Base *The Sella Turcica and ...
척수혈관질환 ( Vascular diseases of spinal cord ) *847 views. Computational Intelligence: Methods and Applications *573 views ...
Acute Myelopathy: Vascular and Infectious Diseases. Neurol Clin. 2021 May;39(2):489-512. doi: 10.1016/j.ncl.2021.01.011 [PubMed ... Neck hyperextension cervical spinal cord injury (spinal cord contusion).. *Syrinx (dilation of the central canal of the spinal ... defining the level of a spinal cord lesion. *Sensory spinal cord level: *Light touch is perceived by both the spinothalamic ... The cauda equina is composed of nerve roots L2-L5 and S1-S5, which exit the spinal cord below the end of the spinal cord ( ...
Posterior myelopathy is considered a type of vascular myelopathy or vascular disease of the spinal cord. Vascular refers to the ... In the spinal cord, the posterior horn is a horn-shaped area of gray matter (tissue), which ... matter regions supplied by the posterior spinal artery. White matter is a group of white nerve fibers that conduct nerve ...
Neuropathology is a specialty within the study of pathology focused on the disease of the brain, spinal cord, and neural tissue ... Vascular neurosurgery includes clipping of aneurysms and performing carotid endarterectomy (CEA).. *Stereotactic neurosurgery, ... Some indications for spine surgery include spinal cord compression resulting from trauma, arthritis of the spinal discs, or ... mitochondria disease, and any disorder that has neural deterioration in the brain or spinal cord.[34][35] ...
This encompasses spinal cord and spine disease, degenerative and demyelinating diseases of the central nervous system, strokes ... Professor of Surgery (Vascular Surgery) Clinical Focus Vascular Surgery, Peripheral Arterial Disease, Aortic Aneurysms, Carotid ... animal models of arterial disease, arterial remodeling and flow changes in spinal cord injury, genetic regulation of arterial ... Professor of Surgery (Vascular), Emeritus Clinical Focus Vascular Surgery Research Interests I am interested in thrombosis and ...
Briefly discusses what happens when diseases or injuries affect the nervous system. Covers emergency symptoms like loss of ... Blood supply problems (vascular disorders).. *Injuries (trauma), especially injuries to the head and spinal cord. ... If you have a condition such as diabetes, HIV, cancer, or heart disease, you may need to pay closer attention to certain ... The brain and spinal cord (central nervous system). *The nerve cells that control how you feel pain, touch, or temperature ( ...
Lesions in gray matter and meninges of lumbar spinal cord (pericentral canal gliosis, edema, gray matter gliosis with ... Subtle lesions on brain and cerebellum sections (e.g., gliosis and spongiosis in white matter and vascular leukostasis). ... Marked white matter lesions in peripheral lateral and ventromedial spinal cord white matter, mild perivascular round cell ... less-marked lesions in rest of spinal cord and white matter of midbrain. ...
... abnormalities is widely available and it is known from previously published articles that selective spinal cord tract disease ... or vascular disease. Because in such cases it is uncommon to obtain pathologic correlation and because we seldom determine the ... abnormal cord signal and spinal cord atrophy) found in the more severely affected patients. It is surprising and somewhat ... be applied to normal-appearing cord tissue to show decreased MTRs in affected spinal cords? Although these and other issues are ...
... especially in patients with peripheral vascular disease. Patients with spinal cord injury or other autonomic dysfunction may ... Disease-associated maternal and/or embryofetal risk. *Untreated hypotension associated with spinal anesthesia for cesarean ... myocardial disease, or severe coronary artery disease; may also increase pulmonary arterial pressure and precipitate angina in ... End-stage renal disease (ESRD): Dose-response data indicate increased responsiveness to phenylephrine ...
Spinal cord stimulation for ischemic heart disease and peripheral vascular disease [med. app.] ...
Tumors of the spinal cord *Tethered cord syndrome Traumatic injuries of the central nervous system *Spinal cord injury and ... Lyme s disease). Vascular pathologies and tumors of the brain *Cerebrovascular accidents, intracranial tumors, and urologic ... Fertility issues in men with spinal cord injury * Pregnancy in spinal cord injury Prognosis and follow-up *Evolution and follow ... Disc prolapse and tumors of the spinal cord *Intervertebral disc prolapse *The cauda equina syndrome * ...
Huntingtons Disease Section 4: Multiple Sclerosis Section 5: Parkinsons Disease 36. Spinal Cord Injury 37. Neurogenic and ... Cerebral Vascular Accident/Stroke 34. Traumatic Brain Injury 35. Degenerative Diseases of the Central Nervous System Section 1 ... UPDATED! Completely revised Spinal Cord Injury chapter addresses restoration of available musculature; self-care; independent ... Cardiac and Pulmonary Diseases 45. Oncology 46. Special Needs of the Older Adult 47. HIV Infection and AIDS 48. Polytrauma and ...
... complex vascular malformations and occlusive cerebrovascular disorders including Moyamoya disease. He has also spearheaded ... several early phase clinical trials of stem cell transplantation for chronic stroke and subacute spinal cord injury. Dr. ... Cerebrovascular Diseases, the Journal of Stroke and Cerebrovascular Diseases, Indian Journal of Neurosurgery and World ... congenital heart disease, and neoplasia. His work on hypertension, which affects one billion people worldwide, has demonstrated ...
... focus on a wide range of conditions including Parkinsons disease, ALS, diabetes, heart failure, cancer, stroke and spinal cord ... Our four basic research programs, Immunobiology, Neuroregeneration, Stem Cell Biology and Vascular Biology, ... stroke and spinal cord injury among many more. ... such as Parkinsons disease and Alzheimers disease as well as ... Our four basic research programs focus on a wide range of conditions including Parkinsons disease, ALS, cancer, diabetes, ...
Spinal cord stimulation could expand the benefits of deep brain stimulation on Parkinsons disease motor symptoms to more ... Image of spinal cord and nervous system courtesy of NIH. Deep brain stimulation is a game changer for many Parkinsons disease ... If successful, this procedure would be an alternative for patients who may not be able to have DBS because of vascular problems ... Spinal cord stimulation is already used to treat chronic pain. Researchers are fine-tuning the application to work on the ...
Pulmonary Diseases RHU - Rheumatology SCI - Spinal Cord Injury SM - Sleep Medicine SO - Surgical Oncology TRS - Traumatic ... Vascular Disorders, Cerebral/Peripheral 0505 Agents Used to Treat Shock/Hypotension 0506 Antihypertensive Agents 0507 Diuretics ... Diseases of the Nervous System 2350-2399 Diseases of the Eye 2400-2449 Diseases of the Ear 2450-2499 Diseases of the ... Diseases of the Digestive System 2650-2699 Diseases of the Genitourinary System 2700-2799 Diseases of the Skin and Subcutaneous ...
Global Vascular Boot Market revenue is currently valued at US$ 1.1 billion by 2023 and is expected to reach US$ 1.5 billion by ... spinal cord injury, peripheral vascular disease and many more. Therefore, such advantageous benefit provided by vascular boot ... The increased number of spinal cord surgeries performed due to the increased rate of spinal cord injuries supplements the ... spinal cord injury, peripheral vascular disease and many more, together with increasing healthcare expenditure is boosting the ...
... vascular cognitive impairment, epilepsy, migraine, nervous system infections, spinal cord injury, headache, Parkinsons disease ... These disorders include traumatic brain injury, Alzheimers disease and related dementias, Parkinsons disease, pain, epilepsy ... Research areas include but are not limited to stroke and other cerebrovascular diseases, Alzheimers disease and related ... Disparities in neurological diseases can not be explained by biological risk factors alone and social determinants of health ( ...
Central nervous system vascular accident, Parkinsonian syndrome, cerebral palsy, spinal cord or nerve root lesions, Multiple ... Chronic kidney disease, with chronic hemodialysis or peritoneal dialysis and chronic kidney disease, with impairment of kidney ... Ischemic heart disease with chest pain of cardiac origin If there has been no surgical intervention and the individual reports ... degenerative disease such as Huntingtons chorea, Friedrichs ataxia, and spino-cerebellar degeneration, with manifestations as ...
Study offers clues about the biology of cells in the spinal cord that die off in ALS New research offers clues about the ... biology of cells in the spinal cord that die off in amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. ... Study provides insights into the coordinated dance of nerve and vascular cells Nerve cells need a lot of energy and oxygen. ... Spinal cord stimulation technology instantly improves arm and hand mobility in stroke patients A neurotechnology that ...
Spinal cord and nerve injury can be due to trauma, vascular disease such as a blood clot, some infectious and inflammatory ... There are many possible causes of paralysis, but is usually associated with an injury of the spinal cord or nerves supplying ... Remember that animals with paralysis may have a spinal cord injury and should be handled very gently. ... diseases, degenerative diseases and some cancers. Severe weakness may mimic paralysis. This is most likely to occur in older ...
Overview of Pagets disease, and how to treat it in a natural way. ... the patients may experience collapse of the vertebra or vascular changes that may have an effect on the spinal cord resulting ... Pagets Disease Of Bone. Pagets disease, whose name has been derived from the famous British surgeon Sir James Paget, is a ... In addition, a very unusual type of Pagets disease is found in children, which is known as juvenile Pagets disease. ...
  • Our four basic research programs focus on a wide range of conditions including Parkinson's disease, ALS, cancer, diabetes, heart failure, stroke and spinal cord injury among many more. (hopkinsmedicine.org)
  • Dr. Dawson's discoveries have led to innovative approaches and enhanced the development of new agents to treat neurologic disorders, such as Parkinson's disease and Alzheimer's disease as well as other neurodegenerative disorders. (hopkinsmedicine.org)
  • Deep brain stimulation is a game changer for many Parkinson's disease (PD) patients. (michaeljfox.org)
  • While deep brain stimulation has helped many people living with Parkinson's disease, there are limitations to its use. (michaeljfox.org)
  • Nearly one million people in the United States are living with Parkinson's disease, making it the second-most common neurodegenerative disease after Alzheimer's. (news-medical.net)
  • The warning letter cited an FDA inspection of the clinic which found that it was processing adipose tissue (body fat) into stromal vascular fraction (a cellular product derived from body fat) and administering the product both intravenously or directly into the spinal cord of patients to treat a variety of serious diseases or conditions, including Parkinson's disease, amyotrophic lateral sclerosis (ALS), chronic obstructive pulmonary disease (COPD), heart disease, and pulmonary fibrosis. (biopharminternational.com)
  • California Stem Cell Treatment Center products are also being used for the experimental treatment of patients who suffer from a variety of serious diseases or conditions, including cancer, arthritis, stroke, ALS, multiple sclerosis, macular degeneration, Parkinson's disease, COPD, and diabetes. (biopharminternational.com)
  • [ 1 ] Spinal cord hemorrhage is most commonly caused by trauma, vascular malformations, or bleeding diatheses. (medscape.com)
  • With trauma, shear forces acting upon the spinal cord and surrounding structures may lead to hemorrhage and vascular damage. (medscape.com)
  • Autopsy studies demonstrate the hemorrhagic necrosis of the spinal cord that is caused by trauma. (medscape.com)
  • These fellowships include pediatric neurosurgery , trauma/neurocritical care, functional and stereotactic surgery, surgical neuro- oncology , radiosurgery, neurovascular surgery, skull-base surgery, peripheral nerve and complex spinal surgery. (wikipedia.org)
  • Injuries (trauma), especially injuries to the head and spinal cord. (healthwise.net)
  • Spinal cord and nerve injury can be due to trauma, vascular disease such as a blood clot, some infectious and inflammatory diseases, degenerative diseases and some cancers. (lortsmith.com)
  • Individuals who have developed Paget's disease are also likely to suffer from certain complications, such as the bones in the affected areas being inclined to breakage or fracture owing to even slight trauma. (herbs2000.com)
  • Their stem cell experience has focused on the healing of brain trauma, spinal cord injury, cerebral vascular diseases, multiple sclerosis and myelitis, among other illnesses. (mediescapes.com)
  • In 2008, Paolo Zamboni, a vascular surgeon in Italy, hypothesized a new cause of multiple sclerosis (MS) involving abnormalities in the veins draining the brain and spinal cord, which he called chronic cerebrospinal venous insufficiency (CCSVI). (mun.ca)
  • There are now hundreds of Facebook groups with tens of thousands of participants, devoted to promoting vascular treatment for MS, even though virtually none of Canada s researchers and not even the Multiple Sclerosis Society of Canada have advocated for publicly funded clinical trials on the treatment of CCSVI. (mun.ca)
  • Central nervous system (CNS) vascular malformations encompass a wide range of arterial and venous anomalies with various presentations, a variable clinical course, and a variety of complication rates. (medscape.com)
  • Spinal vascular malformations consist of an abnormal connection between normal arterial and venous pathways. (medscape.com)
  • The etiology of vascular malformations of the spinal cord has not been clearly defined. (medscape.com)
  • These vascular malformations develop near a spinal dural artery, forming an abnormal arteriovenous communication with the venous circulation. (medscape.com)
  • Due to increased utilization of imaging techniques of the craniospinal axis over past decades, more vascular malformations are being detected. (medscape.com)
  • Spinal cord vascular malformations (arterial and venous) represent a heterogeneous group of blood vessel disorders that affect the spinal cord parenchyma either directly or indirectly. (medscape.com)
  • [ 2 ] Vascular malformations of the spinal cord include spinal arteriovenous malformations (AVMs), dural arteriovenous fistulas (AVFs), spinal hemangiomas , cavernous angiomas , and aneurysms . (medscape.com)
  • This article focuses on the most prevalent spinal vascular malformations-AVMs and AVFs. (medscape.com)
  • This is the most common type of malformation, accounting for 70% of all spinal vascular malformations. (medscape.com)
  • [ 5 ] Patients with these malformations become symptomatic because the AVF creates venous congestion and hypertension, resulting in hypoperfusion, hypoxia, and edema of the spinal cord. (medscape.com)
  • [ 5 ] Glomus AVMs are the most commonly encountered intramedullary vascular malformations, representing about 20% of all spinal vascular malformations. (medscape.com)
  • In non-traumatic cases, vascular malformations and coagulopathies are the most common etiologies, in almost equal proportions. (medscape.com)
  • In the past, certain conditions that would have required open surgery such as aneurysms, carotid artery disease, vascular malformations, and tumors of the head, brain, neck, and spine can now be considered for a minimally invasive treatment using a neurointerventional surgery approach to reach the problem. (ausrad.com)
  • Among them, isolated spinal artery aneurysms are uncommon and a limited number of cases have been reported in the literature. (elsevierpure.com)
  • Conclusion: Isolated spinal artery aneurysms represent a rare cause of intracranial SAH. (elsevierpure.com)
  • [9] During the Middle Ages in Al-Andalus from 936 to 1013 AD, Al-Zahrawi performed surgical treatments of head injuries, skull fractures, spinal injuries, hydrocephalus , subdural effusions and headache. (wikipedia.org)
  • The increasing prevalence of various leg ulcers and increased accident rate of injuries driving the global market for a vascular boot during the forecast period. (futuremarketinsights.com)
  • The increased number of spinal cord surgeries performed due to the increased rate of spinal cord injuries supplements the market growth. (futuremarketinsights.com)
  • Europe accounts for the second highest share of the vascular foot market owing to the increased prevalence of vascular-related injuries in the region. (futuremarketinsights.com)
  • Spinal cord stimulation for ischemic heart disease and peripheral vascular disease [med. (emf-portal.org)
  • These investigators made a splash earlier this year when they published in Scientific Reports that spinal cord stimulation in pre-clinical models improved motor symptoms and showed neuronal protection. (michaeljfox.org)
  • The Michael J. Fox Foundation (MJFF) did not fund that study, but we have funded research from this same group of investigators to test spinal stimulation in a more advanced model. (michaeljfox.org)
  • Spinal stimulation could extend this therapeutic approach to many more. (michaeljfox.org)
  • Spinal stimulation uses the same technique, but rather than blocking the signals where they begin, the therapy blocks them further downstream. (michaeljfox.org)
  • Spinal cord stimulation is already used to treat chronic pain. (michaeljfox.org)
  • The same enhancements could be used in spinal stimulation. (michaeljfox.org)
  • Vascular lesions of the brain and spinal cord are commonly encountered in clinical practice and can lead to diagnostic, prognostic, and therapeutic challenges. (medscape.com)
  • As a collolary, one could determine if newer antiviral treatment strategies would have an equal effect on brain and spinal cord lesions as determined by follow-up MR imaging. (ajnr.org)
  • Sensory ataxia can occur with spinal cord, brain stem (the lower part of the brain near the neck), and cerebral locations of lesions. (wolvesdenranch.com)
  • Vascular disorders of the spine are more rare than cerebral vascular entities but can result in significant morbidity. (medscape.com)
  • International experts show how to generate state-of-the-art images and define diagnoses from crucial clinical/pathologic MR imaging correlations for neurologic, neurosurgical, and psychiatric diseases spanning fetal CNS anomalies to disorders of the aging brain. (chipsbooks.com)
  • Neurosurgery or neurological surgery , known in common parlance as brain surgery , is the medical specialty concerned with the surgical treatment of disorders which affect any portion of the nervous system including the brain , spinal cord and peripheral nervous system . (wikipedia.org)
  • Blood supply problems (vascular disorders). (healthwise.net)
  • If successful, this procedure would be an alternative for patients who may not be able to have DBS because of vascular problems, mood disorders or aversion to brain surgery. (michaeljfox.org)
  • It covers a broad range of material that is presented by experts in each field, such as discography, percutaneous discectomy, vertebroplasty and balloon kyphoplasty, epidural steroid injections, selective nerve root blocks, autonomic nerve blocks, spinal stimulator implantation, and spine v- cular intervention. (springer.com)
  • Preparation for placement of a permanent spinal cord stimulator usually necessitates a trial procedure, which allows both the SCS team and the subject to determine whether or not a permanent implant would provide substantial or adequate pain relief and improvements in QOL. (medscape.com)
  • What Is A Spinal Cord Stimulator? (renotahoepain.com)
  • however, for patients who don't respond to nonsurgical treatments, a spinal cord stimulator may be able to provide you with more effective relief. (renotahoepain.com)
  • A spinal cord stimulator is a device that's implanted under the skin where it sends mild electrical currents to the spinal cord every time the patient experiences pain. (renotahoepain.com)
  • These are only some of the conditions that can benefit from a spinal cord stimulator. (renotahoepain.com)
  • A spinal cord stimulator is often recommended along with other treatment options such as physical therapy, rehabilitation, and relaxation techniques. (renotahoepain.com)
  • By interfering with them using a spinal cord stimulator, you can reduce pain and improve your quality of life. (novowellnesscenter.com)
  • To find out if you're a good candidate for a spinal cord stimulator, call either office in Aiken or Hilton Head Island, South Carolina, or request an appointment online today. (novowellnesscenter.com)
  • A spinal cord stimulator is an electrical device that a surgeon implants under your skin. (novowellnesscenter.com)
  • Novo Wellness implants your spinal cord stimulator during a surgery. (novowellnesscenter.com)
  • With a spinal cord stimulator, you can reduce or even eliminate your need for pharmaceutical pain medications. (novowellnesscenter.com)
  • For ideal results, Novo Wellness might suggest integrating a spinal cord stimulator into a comprehensive treatment plan that includes physical therapy, exercises, relaxation techniques, and other approaches to improve your mobility and functioning. (novowellnesscenter.com)
  • What maintenance does my spinal cord stimulator require? (novowellnesscenter.com)
  • Living with a spinal cord stimulator can significantly reduce your pain, but you must keep up on its maintenance and take some precautions with certain activities. (novowellnesscenter.com)
  • A spinal cord stimulator can improve your quality of life by reducing pain and the need for pain medications. (novowellnesscenter.com)
  • Intramedullary spinal cord tumors, both primary CNS and metastatic (especially renal cell carcinoma), can also bleed and lead to hematomyelia. (medscape.com)
  • Membrane surrounding the brain and spinal cord ( meningitis ). (healthwise.net)
  • The most common cause of spinal cord hemorrhage is traumatic injury. (medscape.com)
  • Predictors and outcomes of spinal cord injury following complex branched/fenestrated endovascular aortic repair in the US Aortic Research Consortium. (harvard.edu)
  • Outcomes following thoracic endovascular aortic repair for blunt thoracic aortic injury stratified by Society for Vascular Surgery grade. (harvard.edu)
  • Therefore, a sensory level to light touch may be absent unless both of these are involved (e.g., a complete injury that involves all spinal cord tracts). (emcrit.org)
  • Remember that animals with paralysis may have a spinal cord injury and should be handled very gently. (lortsmith.com)
  • There are many possible causes of paralysis, but is usually associated with an injury of the spinal cord or nerves supplying the limb. (lortsmith.com)
  • Hematomyelia more commonly involves the cervical rather than thoracic or lumbar spinal cord. (medscape.com)
  • A neurotechnology that stimulates the spinal cord instantly improves arm and hand mobility, enabling people affected by moderate to severe stroke to conduct their normal daily activities more easily, report researchers from the University of Pittsburgh and Carnegie Mellon University today in Nature Medicine. (news-medical.net)
  • Dementia in people who have risk factors or symptoms of a stroke is often vascular dementia. (msdmanuals.com)
  • Generally, people affected by Paget's disease do not have any symptoms, at least in the initial stages of developing this chronic bone disorder, and it is interesting to note that it is often identified when the X-rays of the patient are taken for diagnosing other medical conditions. (herbs2000.com)
  • Chronic diseases and conditions are serious threats to the population's health. (cdc.gov)
  • Chronic diseases represent seven of the top ten causes of mortality in the U.S. and are major economic drivers underlying burgeoning national health costs. (cdc.gov)
  • We propose a set of contributing factors and a model to help better understand the relationship of disability with chronic disease. (cdc.gov)
  • Dramatic escalation in rates of chronic diseases and conditions make them a major public health problem in the U.S.1 and globally.2 We are beginning to recognize the major contribution that chronic diseases make to the poor health of people with disabilities. (cdc.gov)
  • Among the most significant chronic diseases are heart disease, diabetes, cancer and respiratory problems.2 The major modifiable risks for these chronic diseases relate to lifestyle behaviors such as smoking, physical inactivity and poor nutrition, and excessive use of alcohol. (cdc.gov)
  • This inclusion of disability as a chronic condition does not allow examination of the health risks posed by chronic diseases to people with pre-existing functional limitations. (cdc.gov)
  • In such a case, one could suggest a more peripheral site of primary abnormality, with a secondary effect on the spinal cord. (ajnr.org)
  • In addition, the patients may experience collapse of the vertebra or vascular changes that may have an effect on the spinal cord resulting in paraplegia. (herbs2000.com)
  • Autonomic nerves run within the grey matter, near the center of the cord. (emcrit.org)
  • For perfusion, three longitudinal vessels form an anastomotic network that supplies the spinal cord: two posterior spinal arteries, and the anterior spinal artery. (medscape.com)
  • The blood flow to the posterior spinal arteries originates from intradural vertebral arteries, which are from medullary segments of the posterior inferior cerebellar arteries and segmental radiculopial arteries. (medscape.com)
  • The posterior spinal arteries give rise to the "vasocorona," which eventually branches into peripheral arteries and mainly supplies the white matter of the spinal cord. (medscape.com)
  • Reduced blood flow to the spinal cord which is supplied by the anterior spinal artery and the paired posterior spinal arteries. (harvard.edu)
  • Spinal nerves and corresponding sensory dermatomes are shown above. (emcrit.org)
  • Nerves to the cervical cord are located closest to the middle of the cord, whereas nerves to the sacrum are located farthest towards the edges of the spinal cord. (emcrit.org)
  • It includes the brain, the spinal cord, and all the nerves in the body. (healthwise.net)
  • Preoperative Spinal Drain Placement is Associated with Reduced Risk of Spinal Cord Ischemia in Patients Undergoing Thoracic Endovascular Aortic Repair for Aortic Dissection. (harvard.edu)
  • Patients with partial cord involvement may fail to display a sensory level. (emcrit.org)
  • Two patients did not undergo resection or transplantation and died of progressive disease. (stanford.edu)
  • Following transplantation, 5 patients were alive at the end of the follow-up period and one died of recurrent disease. (stanford.edu)
  • It is well recognized that patients with AIDS can present with a myelopathy unrelated to a tumor, opportunistic infection, or vascular disease. (ajnr.org)
  • Despite the small number of patients in each of their MR and clinical categories, one can recognize a trend toward more striking MR-revealed changes (abnormal cord signal and spinal cord atrophy) found in the more severely affected patients. (ajnr.org)
  • The increasing demand for vascular boots for patients with arterial thrombolytics is expected to drive market growth during the forecast period. (futuremarketinsights.com)
  • Each year in the U.S., 5,000 patients receive a diagnosis of ALS, an incurable neurodegenerative disease that will likely kill them within two to five years. (news-medical.net)
  • Patients affected by Paget's disease experience bone pain in the bones that have developed this condition. (herbs2000.com)
  • Neurointerventional surgery provides a complete spectrum of minimally invasive services for the diagnosis and treatment of patients with vascular problems related to the brain and spinal cord. (ausrad.com)
  • Patients with vascular TOS may require repair of veins and arteries. (brighamandwomens.org)
  • Results: Both patients presented with an atypical intracranial SAH and were also found to have spinal SAH caused by a ruptured posterior spinal aneurysm. (elsevierpure.com)
  • See the MRI below showing spinal malformation of the thoracic spine. (medscape.com)
  • Note that the spinal cord level doesn't line up precisely with the corresponding vertebrae, especially caudal to the thoracic spine. (emcrit.org)
  • Lhermitte's sign (an electric-shock sensation elicited by neck flexion that runs down the spine and sometimes into the limbs) suggests involvement of the posterior columns of the cervical spinal cord. (emcrit.org)
  • Subcortical ischemic vascular cognitive impairment and dementia: Dementia results from tissue damage in the area of the brain under the cortex (the convoluted outer surface of the cerebrum, which is the largest part of the brain). (msdmanuals.com)
  • [ 4 ] These fistulas are created when a radiculomeningeal artery feeds directly into a radicular vein, usually near the spinal nerve root. (medscape.com)
  • Multiple feeding vessels from the anterior spinal artery and/or the posterior spinal circulation typically supply these AVMs. (medscape.com)
  • Blood flows from the anterior spinal artery into medullary branches of the intradural vertebral arteries, and subsequently into segmental radiculomedullary arteries. (medscape.com)
  • Blood flow to the lower portion of the spinal cord (T8-L3) is supplied by a large radicular artery with somewhat variable positioning, termed the Artery of Adamkiewicz. (medscape.com)
  • The central perfusion region receives blood supply from the anterior spinal artery, which forms the central sulcus artery and courses into the ventral median sulcus and supplies the grey matter of spinal cord. (medscape.com)
  • Krishnan P, Banerjee TK, Saha M. Congestive myelopathy (Foix-Alajouanine Syndrome) due to intradural arteriovenous fistula of the filum terminale fed by anterior spinal artery: Case report and review of literature. (medscape.com)
  • matter regions supplied by the posterior spinal artery. (medfriendly.com)
  • Ischemia results from mass effect and disruption of blood flow, which may cause infarction of the spinal cord. (medscape.com)
  • Spinal Cord Ischemia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
  • Prolonged ischemia may lead to INFARCTION of spinal cord tissue. (harvard.edu)
  • This graph shows the total number of publications written about "Spinal Cord Ischemia" by people in Harvard Catalyst Profiles by year, and whether "Spinal Cord Ischemia" was a major or minor topic of these publication. (harvard.edu)
  • Below are the most recent publications written about "Spinal Cord Ischemia" by people in Profiles. (harvard.edu)
  • Intranasal administration of polysulfide prevents neurodegeneration in spinal cord and rescues mice from delayed paraplegia after spinal cord ischemia. (harvard.edu)
  • Spinal arterial dural fistulas commonly arise in an elderly population and are believed to be due to a traumatic occurrence. (medscape.com)
  • Jellema K, Tijssen CC, van Gijn J. Spinal dural arteriovenous fistulas: a congestive myelopathy that initially mimics a peripheral nerve disorder. (medscape.com)
  • Late diagnosis of spinal dural arteriovenous fistulas resulting in severe lower-extremity weakness: a case series. (medscape.com)
  • Endovascular management of spinal dural arteriovenous fistulas. (medscape.com)
  • Endovascular and surgical treatment of spinal dural arteriovenous fistulas. (medscape.com)
  • Hessler C, Regelsberger J, Grzyska U, Illies T, Zeumer H, Westphal M. Therapeutic clues in spinal dural arteriovenous fistulas - a 30 year experience of 156 cases. (medscape.com)
  • Thus, a central spinal cord lesion may cause neurologic deficits in a descending order. (emcrit.org)
  • The vascular boot market is estimated to secure a valuation of US$ 1.1 billion in 2023 and is estimated to rise to US$ 1.5 billion by 2033. (futuremarketinsights.com)
  • Photomicrograph of the cervical spinal cord region showing a thickened subarachnoid vein with a thrombotic occlusion (hematoxylin and eosin stain). (medscape.com)
  • Spinal cord hemorrhage usually presents as sudden, painful myelopathy, which may reflect the anatomic level of the hemorrhage. (medscape.com)
  • Although Chong et al, in this issue of the AJNR (page 1412), do not attempt to answer these questions, they describe the variable MR findings in the spinal cord in AIDS-associated myelopathy, and correlate these findings with the clinical status of the patient. (ajnr.org)
  • Equally surprising is the finding that a patient with a mild myelopathy could have pronounced MR findings with cord atrophy and intrinsic spinal cord signal abnormalities. (ajnr.org)
  • A strong association between HIV encephalopathy and AIDS-associated myelopathy would be reflected in some commonality of MR findings in the brain and spinal cord, namely varying degrees of atrophy, abnormal signal on T2-weighted images, and a lack of abnormal contrast enhancement. (ajnr.org)
  • Researchers at the Francis Crick Institute and UCL have shown that hundreds of proteins and mRNA molecules are found in the wrong place in nerve cells affected by Motor Neuron Disease (MND), also known as Amyotrophic Lateral Sclerosis (ALS). (news-medical.net)
  • Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a fatal motor neuron disease that causes people to gradually lose control of their muscles. (news-medical.net)
  • Researchers at Nagoya University in Japan have discovered a receptor, sigma-1 receptor, and a protein, ATAD3A, that are associated with Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease. (news-medical.net)
  • In virtually all persons with amyotrophic lateral sclerosis (ALS) and in up to half of all cases of Alzheimer's disease (AD) and frontotemporal dementia, a protein called TDP-43 is lost from its normal location in the nucleus of the cell. (news-medical.net)
  • New research offers clues about the biology of cells in the spinal cord that die off in amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. (news-medical.net)
  • Note the thoracolumbar junction with an edematous spinal cord and dilated serpiginous intradural venous plexus. (medscape.com)
  • This malformation consists of a tightly compacted group of arterial and venous vessels (nidus) inside a short segment of the spinal cord. (medscape.com)
  • The pial surface and superficial regions of the spinal cord are drained by radial veins and the coronal venous plexus. (medscape.com)
  • Evaluating for a sensory level using a pin to detect pain sensation is more sensitive to detect a spinal level originating from a lesion in the spinothalamic tract. (emcrit.org)
  • Motor weakness may be used to evaluate the level of a spinal lesion that involves the corticospinal tract. (emcrit.org)
  • The brain and spinal cord (central nervous system). (healthwise.net)
  • If the source of the disease is suspected to be in the nervous system, a sample of cerebrospinal fluid (CSF) will be taken for laboratory analysis. (wolvesdenranch.com)
  • While it is established that cardiovascular disease (CVD) is typically associated with middle or old age, atherosclerosis often initiates in early childhood when deposits of cholesterol form fatty streaks in the intima of large arteries. (umc.edu)
  • Summary of intramedullary spinal cord hemorrhage etiologies, with history and associated clues, common imaging findings, and representative management. (medscape.com)
  • Background: Approximately 1 % of cases of intracranial subarachnoid hemorrhage (SAH) are caused by spinal vascular pathologies. (elsevierpure.com)
  • Centers for Disease Control and Prevention. (cdc.gov)
  • The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. (cdc.gov)
  • The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
  • Read Carefully before Using The Public Health Service Act (Section 308 (d)) provides that the data collected by the National Center for Health Statistics (NCHS), Centers for Disease Control and Prevention (CDC), may be used only for the purpose of health statistical reporting and analysis. (cdc.gov)
  • The NAMCS is a national probability sample survey conducted by the Division of Health Care Statistics, National Center for Health Statistics (NCHS), Centers for Disease Control and Prevention (CDC). (cdc.gov)
  • The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention. (cdc.gov)
  • On the other hand, if no significant association between brain and spinal cord MR findings were present, it would be difficult to imply that an HIV infection of just the spinal cord were present. (ajnr.org)
  • It is believed that a viral infection may possibly set off Paget's disease in individuals having inherited the propensity of the genes to develop this disease by possessing these specific genes. (herbs2000.com)
  • The young adults (2-3 cm in length) enter the vascular system and are carried to the heart and pulmonary arteries, arriving as early as 70 days after infection. (capcvet.org)
  • Monkeypox (mpox) is a disease caused by infection with Monkeypox virus (MPXV), an Orthopoxvirus (OPXV) in the same genus as Variola virus , which causes smallpox. (cdc.gov)
  • Hemorrhage affecting the spinal cord is rare. (medscape.com)
  • Spinal cord hemorrhage can be divided based on etiology, into two types: (1) traumatic and (2) non-traumatic. (medscape.com)
  • Hematomyelia is defined as the presence of a well-defined focus of hemorrhage within the spinal cord itself. (medscape.com)
  • Abnormal gait may be caused by diseases in different areas of the body. (medlineplus.gov)
  • Alzheimer Disease Alzheimer disease is a progressive loss of mental function, characterized by degeneration of brain tissue, including loss of nerve cells, the accumulation of an abnormal protein called beta-amyloid. (msdmanuals.com)
  • CAA is caused by accumulation of beta-amyloid (an abnormal protein) in blood vessels in brain, Most people with Alzheimer disease have CAA, but it also occurs in the brains of many healthy older people. (msdmanuals.com)
  • Instability is defined by abnormal spinal alignment under physiologic conditions (loads) such as standing, walking, bending, or lifting. (bvsalud.org)
  • The news of the first BIOFLEX-I Pulsar-18 implant follows the recently presented 12-month results of the European 4EVER study , which investigated both the acute and long-term performance of 4F compatible devices from Biotronik in the lower limbs, or peripheral vascular procedures. (vascularnews.com)
  • The study will evaluate the safety and efficacy of the Astron and Pulsar stent families for the treatment of peripheral arterial disease. (vascularnews.com)
  • The spinal cord is composed of neuronal pathways, glial tissue, and interwoven vascular structures that perfuse the spinal parenchyma. (medscape.com)
  • Vascular dementia is loss of mental function due to destruction of brain tissue because its blood supply is reduced or blocked. (msdmanuals.com)
  • Research at The University of Queensland could eventually help develop viable treatments - and ultimately a cure - for motor neuron disease (MND). (news-medical.net)
  • Depending on the cause and severity of paralysis, your vet may prescribe some medication, give advice on strict cage rest and monitoring at home or recommend further diagnostic imaging like an MRI and possible spinal or orthopaedic surgery. (lortsmith.com)
  • It is worth mentioning here two main factors - the affected bones as well as the severity of the condition determine the symptoms of Paget's disease. (herbs2000.com)
  • Anterior and posterior median spinal veins drain the anterior and posterior regions of the spinal cord, respectively. (medscape.com)
  • This may be harder than it sounds, because spinal cord disease is uncommon and not generally high on our list of considerations. (emcrit.org)
  • The first step towards diagnosis and therapy is recognizing that the patient has some sort of spinal cord pathology. (emcrit.org)