Spinal Cord Vascular Diseases
Spinal Cord
Spinal Cord Injuries
Vascular Diseases
Spinal Cord Diseases
Spinal Cord Compression
Spinal Cord Neoplasms
Peripheral spinal cord hypointensity on T2-weighted MR images: a reliable imaging sign of venous hypertensive myelopathy. (1/17)
BACKGROUND AND PURPOSE: MR findings reported in conjunction with spinal dural arteriovenous fistula (SDAVF) include cord swelling, increased T2 signal within the spinal cord, and parenchymal enhancement, each of which is nonspecific. Enlarged vessels on the cord surface, the most specific MR finding, is noted in only half of SDAVF patients. Nevertheless, we have frequently observed MR peripheral hypointensity of the spinal cord in SDAVF on T2-weighted images, which is not characteristic of nonvascular or nonhemorrhagic causes of myelopathy and which has not been described in association with SDAVF. We hypothesized that peripheral cord hypointensity might reliably suggest the diagnosis of SDAVF or other causes of venous hypertensive myelopathy. METHODS: We reviewed the MR findings in 11 consecutive cases of angiographically confirmed symptomatic SDAVF and in four cases of intracranial dural arteriovenous fistula with spinal drainage, a lesion that also causes spinal cord deficits mediated by venous hypertensive myelopathy. RESULTS: In each case, T2 hypointensity involving the cord periphery was present. This sign has not been previously described in association with either SDAVF or other causes of venous hypertensive myelopathy. It appears, however, to be a relatively constant imaging feature of SDAVF. CONCLUSION: In the absence of spinal hemorrhage, T2 hypointensity involving the periphery of the spinal cord suggests venous hypertensive myelopathy as a cause of spinal cord dysfunction. (+info)Neurovascular complications of marfan syndrome: a retrospective, hospital-based study. (2/17)
BACKGROUND AND PURPOSE: Small case series have associated Marfan syndrome with cerebral and spinal ischemia or hemorrhage. However, there has been no investigation of the frequency and etiology of neurovascular disorders in a large series of Marfan patients. METHODS: We conducted a retrospective, hospital-based study of all Marfan syndrome patients seen in an 8-year period. Records were reviewed in detail, and clinical characteristics of those with and without a neurovascular diagnosis compared. RESULTS: Of 513 patients, 18 (3.5%) had a neurovascular diagnosis, as follows: transient ischemic attack (11), cerebral infarction (2), spinal cord infarction (2), subdural hematoma (2), and spinal subarachnoid hemorrhage (1). A cardioembolic source was identified in 12 of 13 patients with cerebral ischemia, as follows: prosthetic heart valves (9), mitral valve prolapse (2), and atrial fibrillation (1). Chronic anticoagulant therapy was a likely cause in 2 of 3 patients with hemorrhagic events. Compared with other Marfan syndrome patients, those with neurovascular events were older (39.6 versus 31.7 years, P=0.04) and more likely to be in atrial fibrillation (22.2% versus 3.2%, P=<0.01), to have prosthetic heart valves (61.1% versus 7.7%, P=0.001), and to be taking anticoagulant therapy (72.2% versus 16.1%, P<0.001). Aortic disease, a putative factor in the etiology of neurovascular complications, was present in equal measure in Marfan patients with and without neurovascular complications (78% versus 65%, P=NS). CONCLUSIONS: Neurovascular complications of Marfan syndrome are rare during 8 years of follow-up, and generally are ischemic in nature. A high-risk cardiac source was identified in the majority. A significant association with vascular dissection was not established. (+info)Spinal tanycytic ependymoma with hematomyelia--case report--. (3/17)
A 58-year-old man presented with an extremely rare case of "pure type" spinal tanycytic ependymoma associated with hematomyelia manifesting as sensory disturbance of the bilateral hands and weakness of the right arm. Magnetic resonance imaging demonstrated a tumor in the spinal cord from C-2 to C-4 levels. The soft gelatinous tumor was subtotally resected and the adjacent chronic liquid hematoma was aspirated. The immunohistochemical and ultrastructural findings indicated a diagnosis of tanycytic ependymoma. (+info)Transient traumatic spinal venous hypertensive myelopathy. (4/17)
We present a case of a reversible spinal venous hypertensive myelopathy that occurred following a traumatic mediastinal hematoma. The mediastinal hematoma caused compression of the brachiocephalic vein, resulting in elevation of the venous pressures that ultimately resulted in dilation of the epidural venous plexus and spinal cord edema. The secondary neurologic deficits were the culmination of venous outflow obstruction at the level of the spinal cord that resolved on the resolution of the mediastinal hematoma. (+info)Usefulness of combined electrophysiological examinations for detection of neural dysfunction in cats with lumbar hematomyelia. (5/17)
We conducted combined electrophysiological examinations including F-wave, motor nerve conduction velocity (MNCV), spinal cord-evoked potential (SCEP), and needle electromyography (EMG) in two cats involved in traffic accidents that consequently developed hind limb paralysis caused by lumbar hematomyelia. F-wave could no longer be elicited within 3 days after the accident, and the MNCV and compound muscle action potential (CMAP) amplitude decreased in a time-dependent manner, with CMAP no longer being evoked after 7 or 8 days. EMG showed abnormalities such as fibrillation and positive sharp waves after 6 to 8 days. These results suggest that such combined electrophysiological examinations may provide objective, quantitative data for motor nerve dysfunction in cats with lumbar hematomyelia. (+info)Spinal arteriovenous shunts presenting as intracranial subarachnoid haemorrhage. (6/17)
BACKGROUND: In approximately 5% of patients with intracranial subarachnoid haemorrhage (SAH), the cause is another than a ruptured aneurysm or perimesencephalic haemorrhage. One of these causes is a spinal arteriovenous shunt (SAVS). The aim of this study was to investigate the characteristics of patients with SAVS who present with intracranial SAH without symptoms and signs suggesting a spinal cause. METHODS: We systematically reviewed the literature and searched the SAH database of the University Medical Center Utrecht, The Netherlands, for patients with SAVS presenting with intracranial SAH and studied the characteristics of patients with SAVS whose clinical presentation mimicked intracranial SAH caused by rupture of a saccular aneurysm. RESULTS: Thirty-five patients were identified after a review of the literature. In our SAH database, comprising 2142 patients included in the period 1985-2004, we found one patient (0.05%, 95 % CI 0.006- 0.3%). SAH due to SAVS occurred at any age (4-72 years). The SAVS was located at the craniocervical junction in 14 patients, at the cervical level in 11, and at the thoracolumbar level in the remaining 11 patients. The majority of patients (n = 26, 72%) had no disabling deficits at discharge or follow-up. CONCLUSION: Rupture of a SAVS presenting as intracranial SAH is rare and can occur at any age. The SAVS can be located not only at the craniocervical junction or cervical level but also in the thoracolumbar region. Most patients with SAVS presenting as intracranial SAH have a good recovery. (+info)Hematomyelia caused by ruptured intramedullary spinal artery aneurysm associated with extramedullary spinal arteriovenous fistula--case report. (7/17)
A 53-year-old woman presented with a ruptured intramedullary aneurysmal dilatation fed by the anterior spinal artery associated with an arteriovenous malformation located in the ventral cervical spinal cord. She developed tetraparesis and respiratory dysfunction. The neurological deterioration was caused by hematomyelia due to the ruptured aneurysmal dilatation and progression of edema in the upper cervical spinal cord due to venous hypertension associated with additional hematoma in the medulla oblongata. Endovascular embolization of both C-1 and C-2 radicular arteries was performed with Guglielmi detachable coils, but components fed by small branches such as the radiculo-pial artery were not obliterated. Surgery was performed for extirpation of the arteriovenous malformation and cervical intramedullary hematoma, and excision of the aneurysmal dilatation through a transcondylar approach combined with vertebral artery transposition. Postoperatively, she overcame several complications such as pneumonia and endocarditis, and had only moderate weakness of the right upper and lower limbs. This case indicates that surgical intervention for high cervical intramedullary lesion may be very effective. (+info)Intramedullary cavernoma presenting with hematomyelia: report of two girls. (8/17)
(+info)Spinal cord vascular diseases refer to a group of disorders that affect the blood vessels of the spinal cord. These conditions can result in insufficient blood supply to the spinal cord tissue, leading to ischemia (lack of oxygen) and infarction (tissue death). There are several types of spinal cord vascular diseases, including:
1. Spinal Cord Infarction: This is a rare condition that occurs due to the blockage or narrowing of the arteries supplying blood to the spinal cord. It can result in sudden onset of weakness, numbness, or paralysis in parts of the body served by the affected spinal cord region.
2. Spinal Cord Aneurysm: This is a localized dilation or bulging of a weakened area in the wall of a blood vessel that supplies the spinal cord. If an aneurysm ruptures, it can cause bleeding into the spinal cord tissue, leading to neurological deficits.
3. Spinal Cord Arteriovenous Malformations (AVMs): These are abnormal connections between the arteries and veins in the spinal cord. AVMs can lead to bleeding, ischemia, or both, resulting in various neurological symptoms.
4. Spinal Cord Dural Arteriovenous Fistulas (dAVFs): These are abnormal communications between the spinal artery and a vein located outside the dura mater (the protective covering of the spinal cord). dAVFs can cause venous congestion, leading to ischemia and neurological dysfunction.
5. Spinal Cord Vasculitis: This is an inflammation of the blood vessels in the spinal cord, which can lead to narrowing or blockage of the affected vessels. It can result in various neurological symptoms, such as weakness, numbness, or pain.
Treatment for spinal cord vascular diseases depends on the specific condition and its severity. Treatment options may include medications, surgery, endovascular procedures, or a combination of these approaches.
The spinal cord is a major part of the nervous system, extending from the brainstem and continuing down to the lower back. It is a slender, tubular bundle of nerve fibers (axons) and support cells (glial cells) that carries signals between the brain and the rest of the body. The spinal cord primarily serves as a conduit for motor information, which travels from the brain to the muscles, and sensory information, which travels from the body to the brain. It also contains neurons that can independently process and respond to information within the spinal cord without direct input from the brain.
The spinal cord is protected by the bony vertebral column (spine) and is divided into 31 segments: 8 cervical, 12 thoracic, 5 lumbar, 5 sacral, and 1 coccygeal. Each segment corresponds to a specific region of the body and gives rise to pairs of spinal nerves that exit through the intervertebral foramina at each level.
The spinal cord is responsible for several vital functions, including:
1. Reflexes: Simple reflex actions, such as the withdrawal reflex when touching a hot surface, are mediated by the spinal cord without involving the brain.
2. Muscle control: The spinal cord carries motor signals from the brain to the muscles, enabling voluntary movement and muscle tone regulation.
3. Sensory perception: The spinal cord transmits sensory information, such as touch, temperature, pain, and vibration, from the body to the brain for processing and awareness.
4. Autonomic functions: The sympathetic and parasympathetic divisions of the autonomic nervous system originate in the thoracolumbar and sacral regions of the spinal cord, respectively, controlling involuntary physiological responses like heart rate, blood pressure, digestion, and respiration.
Damage to the spinal cord can result in various degrees of paralysis or loss of sensation below the level of injury, depending on the severity and location of the damage.
Spinal cord injuries (SCI) refer to damage to the spinal cord that results in a loss of function, such as mobility or feeling. This injury can be caused by direct trauma to the spine or by indirect damage resulting from disease or degeneration of surrounding bones, tissues, or blood vessels. The location and severity of the injury on the spinal cord will determine which parts of the body are affected and to what extent.
The effects of SCI can range from mild sensory changes to severe paralysis, including loss of motor function, autonomic dysfunction, and possible changes in sensation, strength, and reflexes below the level of injury. These injuries are typically classified as complete or incomplete, depending on whether there is any remaining function below the level of injury.
Immediate medical attention is crucial for spinal cord injuries to prevent further damage and improve the chances of recovery. Treatment usually involves immobilization of the spine, medications to reduce swelling and pressure, surgery to stabilize the spine, and rehabilitation to help regain lost function. Despite advances in treatment, SCI can have a significant impact on a person's quality of life and ability to perform daily activities.
Vascular diseases are medical conditions that affect the circulatory system, specifically the blood vessels (arteries, veins, and capillaries). These diseases can include conditions such as:
1. Atherosclerosis: The buildup of fats, cholesterol, and other substances in and on the walls of the arteries, which can restrict blood flow.
2. Peripheral Artery Disease (PAD): A condition caused by atherosclerosis where there is narrowing or blockage of the peripheral arteries, most commonly in the legs. This can lead to pain, numbness, and cramping.
3. Coronary Artery Disease (CAD): Atherosclerosis of the coronary arteries that supply blood to the heart muscle. This can lead to chest pain, shortness of breath, or a heart attack.
4. Carotid Artery Disease: Atherosclerosis of the carotid arteries in the neck that supply blood to the brain. This can increase the risk of stroke.
5. Cerebrovascular Disease: Conditions that affect blood flow to the brain, including stroke and transient ischemic attack (TIA or "mini-stroke").
6. Aneurysm: A weakened area in the wall of a blood vessel that causes it to bulge outward and potentially rupture.
7. Deep Vein Thrombosis (DVT): A blood clot that forms in the deep veins, usually in the legs, which can cause pain, swelling, and increased risk of pulmonary embolism if the clot travels to the lungs.
8. Varicose Veins: Swollen, twisted, and often painful veins that have filled with an abnormal collection of blood, usually appearing in the legs.
9. Vasculitis: Inflammation of the blood vessels, which can cause damage and narrowing, leading to reduced blood flow.
10. Raynaud's Phenomenon: A condition where the small arteries that supply blood to the skin become narrowed, causing decreased blood flow, typically in response to cold temperatures or stress.
These are just a few examples of vascular conditions that fall under the umbrella term "cerebrovascular disease." Early diagnosis and treatment can significantly improve outcomes for many of these conditions.
Spinal cord diseases refer to a group of conditions that affect the spinal cord, which is a part of the central nervous system responsible for transmitting messages between the brain and the rest of the body. These diseases can cause damage to the spinal cord, leading to various symptoms such as muscle weakness, numbness, pain, bladder and bowel dysfunction, and difficulty with movement and coordination.
Spinal cord diseases can be congenital or acquired, and they can result from a variety of causes, including infections, injuries, tumors, degenerative conditions, autoimmune disorders, and genetic factors. Some examples of spinal cord diseases include multiple sclerosis, spina bifida, spinal cord injury, herniated discs, spinal stenosis, and motor neuron diseases such as amyotrophic lateral sclerosis (ALS).
The treatment for spinal cord diseases varies depending on the underlying cause and severity of the condition. Treatment options may include medication, physical therapy, surgery, and rehabilitation. In some cases, the damage to the spinal cord may be irreversible, leading to permanent disability or paralysis.
Spinal cord compression is a medical condition that refers to the narrowing of the spinal canal, which puts pressure on the spinal cord and the nerves that branch out from it. This can occur due to various reasons such as degenerative changes in the spine, herniated discs, bone spurs, tumors, or fractures. The compression can lead to a range of symptoms including pain, numbness, tingling, weakness, or loss of bladder and bowel control. In severe cases, it can cause paralysis. Treatment options depend on the underlying cause and may include physical therapy, medication, surgery, or radiation therapy.
Spinal cord neoplasms refer to abnormal growths or tumors within the spinal cord. These can be benign (non-cancerous) or malignant (cancerous). They originate from the cells within the spinal cord itself (primary tumors), or they may spread to the spinal cord from other parts of the body (metastatic tumors). Spinal cord neoplasms can cause various symptoms depending on their location and size, including back pain, neurological deficits, and even paralysis. Treatment options include surgery, radiation therapy, and chemotherapy.
Peripheral Vascular Diseases (PVD) refer to a group of medical conditions that affect the blood vessels outside of the heart and brain. These diseases are characterized by a narrowing or blockage of the peripheral arteries, which can lead to reduced blood flow to the limbs, particularly the legs.
The primary cause of PVD is atherosclerosis, a buildup of fats, cholesterol, and other substances in and on the walls of the arteries, forming plaques that restrict blood flow. Other risk factors include smoking, diabetes, hypertension, high cholesterol levels, and a family history of vascular disease.
Symptoms of PVD can vary depending on the severity of the condition but may include leg pain or cramping during exercise (claudication), numbness or tingling in the legs, coldness or discoloration of the feet, sores or wounds that heal slowly or not at all, and in severe cases, gangrene.
PVD can increase the risk of heart attack and stroke, so it is essential to diagnose and treat the condition as early as possible. Treatment options include lifestyle changes such as quitting smoking, exercising regularly, and maintaining a healthy diet, medications to control symptoms and reduce the risk of complications, and surgical procedures such as angioplasty or bypass surgery to restore blood flow.
Peter Staats
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Paget's Disease Of Bone
Parkinson's7
- Our four basic research programs focus on a wide range of conditions including Parkinson's disease, ALS, cancer, diabetes, heart failure, stroke and spinal cord injury among many more. (hopkinsmedicine.org)
- Dr. Dawson's discoveries have led to innovative approaches and enhanced the development of new agents to treat neurologic disorders, such as Parkinson's disease and Alzheimer's disease as well as other neurodegenerative disorders. (hopkinsmedicine.org)
- Deep brain stimulation is a game changer for many Parkinson's disease (PD) patients. (michaeljfox.org)
- While deep brain stimulation has helped many people living with Parkinson's disease, there are limitations to its use. (michaeljfox.org)
- Nearly one million people in the United States are living with Parkinson's disease, making it the second-most common neurodegenerative disease after Alzheimer's. (news-medical.net)
- The warning letter cited an FDA inspection of the clinic which found that it was processing adipose tissue (body fat) into stromal vascular fraction (a cellular product derived from body fat) and administering the product both intravenously or directly into the spinal cord of patients to treat a variety of serious diseases or conditions, including Parkinson's disease, amyotrophic lateral sclerosis (ALS), chronic obstructive pulmonary disease (COPD), heart disease, and pulmonary fibrosis. (biopharminternational.com)
- California Stem Cell Treatment Center products are also being used for the experimental treatment of patients who suffer from a variety of serious diseases or conditions, including cancer, arthritis, stroke, ALS, multiple sclerosis, macular degeneration, Parkinson's disease, COPD, and diabetes. (biopharminternational.com)
Trauma8
- [ 1 ] Spinal cord hemorrhage is most commonly caused by trauma, vascular malformations, or bleeding diatheses. (medscape.com)
- With trauma, shear forces acting upon the spinal cord and surrounding structures may lead to hemorrhage and vascular damage. (medscape.com)
- Autopsy studies demonstrate the hemorrhagic necrosis of the spinal cord that is caused by trauma. (medscape.com)
- These fellowships include pediatric neurosurgery , trauma/neurocritical care, functional and stereotactic surgery, surgical neuro- oncology , radiosurgery, neurovascular surgery, skull-base surgery, peripheral nerve and complex spinal surgery. (wikipedia.org)
- Injuries (trauma), especially injuries to the head and spinal cord. (healthwise.net)
- Spinal cord and nerve injury can be due to trauma, vascular disease such as a blood clot, some infectious and inflammatory diseases, degenerative diseases and some cancers. (lortsmith.com)
- Individuals who have developed Paget's disease are also likely to suffer from certain complications, such as the bones in the affected areas being inclined to breakage or fracture owing to even slight trauma. (herbs2000.com)
- Their stem cell experience has focused on the healing of brain trauma, spinal cord injury, cerebral vascular diseases, multiple sclerosis and myelitis, among other illnesses. (mediescapes.com)
Multiple Sclerosis2
- In 2008, Paolo Zamboni, a vascular surgeon in Italy, hypothesized a new cause of multiple sclerosis (MS) involving abnormalities in the veins draining the brain and spinal cord, which he called chronic cerebrospinal venous insufficiency (CCSVI). (mun.ca)
- There are now hundreds of Facebook groups with tens of thousands of participants, devoted to promoting vascular treatment for MS, even though virtually none of Canada s researchers and not even the Multiple Sclerosis Society of Canada have advocated for publicly funded clinical trials on the treatment of CCSVI. (mun.ca)
Malformations13
- Central nervous system (CNS) vascular malformations encompass a wide range of arterial and venous anomalies with various presentations, a variable clinical course, and a variety of complication rates. (medscape.com)
- Spinal vascular malformations consist of an abnormal connection between normal arterial and venous pathways. (medscape.com)
- The etiology of vascular malformations of the spinal cord has not been clearly defined. (medscape.com)
- These vascular malformations develop near a spinal dural artery, forming an abnormal arteriovenous communication with the venous circulation. (medscape.com)
- Due to increased utilization of imaging techniques of the craniospinal axis over past decades, more vascular malformations are being detected. (medscape.com)
- Spinal cord vascular malformations (arterial and venous) represent a heterogeneous group of blood vessel disorders that affect the spinal cord parenchyma either directly or indirectly. (medscape.com)
- [ 2 ] Vascular malformations of the spinal cord include spinal arteriovenous malformations (AVMs), dural arteriovenous fistulas (AVFs), spinal hemangiomas , cavernous angiomas , and aneurysms . (medscape.com)
- This article focuses on the most prevalent spinal vascular malformations-AVMs and AVFs. (medscape.com)
- This is the most common type of malformation, accounting for 70% of all spinal vascular malformations. (medscape.com)
- [ 5 ] Patients with these malformations become symptomatic because the AVF creates venous congestion and hypertension, resulting in hypoperfusion, hypoxia, and edema of the spinal cord. (medscape.com)
- [ 5 ] Glomus AVMs are the most commonly encountered intramedullary vascular malformations, representing about 20% of all spinal vascular malformations. (medscape.com)
- In non-traumatic cases, vascular malformations and coagulopathies are the most common etiologies, in almost equal proportions. (medscape.com)
- In the past, certain conditions that would have required open surgery such as aneurysms, carotid artery disease, vascular malformations, and tumors of the head, brain, neck, and spine can now be considered for a minimally invasive treatment using a neurointerventional surgery approach to reach the problem. (ausrad.com)
Aneurysms2
- Among them, isolated spinal artery aneurysms are uncommon and a limited number of cases have been reported in the literature. (elsevierpure.com)
- Conclusion: Isolated spinal artery aneurysms represent a rare cause of intracranial SAH. (elsevierpure.com)
Injuries4
- [9] During the Middle Ages in Al-Andalus from 936 to 1013 AD, Al-Zahrawi performed surgical treatments of head injuries, skull fractures, spinal injuries, hydrocephalus , subdural effusions and headache. (wikipedia.org)
- The increasing prevalence of various leg ulcers and increased accident rate of injuries driving the global market for a vascular boot during the forecast period. (futuremarketinsights.com)
- The increased number of spinal cord surgeries performed due to the increased rate of spinal cord injuries supplements the market growth. (futuremarketinsights.com)
- Europe accounts for the second highest share of the vascular foot market owing to the increased prevalence of vascular-related injuries in the region. (futuremarketinsights.com)
Stimulation7
- Spinal cord stimulation for ischemic heart disease and peripheral vascular disease [med. (emf-portal.org)
- These investigators made a splash earlier this year when they published in Scientific Reports that spinal cord stimulation in pre-clinical models improved motor symptoms and showed neuronal protection. (michaeljfox.org)
- The Michael J. Fox Foundation (MJFF) did not fund that study, but we have funded research from this same group of investigators to test spinal stimulation in a more advanced model. (michaeljfox.org)
- Spinal stimulation could extend this therapeutic approach to many more. (michaeljfox.org)
- Spinal stimulation uses the same technique, but rather than blocking the signals where they begin, the therapy blocks them further downstream. (michaeljfox.org)
- Spinal cord stimulation is already used to treat chronic pain. (michaeljfox.org)
- The same enhancements could be used in spinal stimulation. (michaeljfox.org)
Lesions3
- Vascular lesions of the brain and spinal cord are commonly encountered in clinical practice and can lead to diagnostic, prognostic, and therapeutic challenges. (medscape.com)
- As a collolary, one could determine if newer antiviral treatment strategies would have an equal effect on brain and spinal cord lesions as determined by follow-up MR imaging. (ajnr.org)
- Sensory ataxia can occur with spinal cord, brain stem (the lower part of the brain near the neck), and cerebral locations of lesions. (wolvesdenranch.com)
Disorders5
- Vascular disorders of the spine are more rare than cerebral vascular entities but can result in significant morbidity. (medscape.com)
- International experts show how to generate state-of-the-art images and define diagnoses from crucial clinical/pathologic MR imaging correlations for neurologic, neurosurgical, and psychiatric diseases spanning fetal CNS anomalies to disorders of the aging brain. (chipsbooks.com)
- Neurosurgery or neurological surgery , known in common parlance as brain surgery , is the medical specialty concerned with the surgical treatment of disorders which affect any portion of the nervous system including the brain , spinal cord and peripheral nervous system . (wikipedia.org)
- Blood supply problems (vascular disorders). (healthwise.net)
- If successful, this procedure would be an alternative for patients who may not be able to have DBS because of vascular problems, mood disorders or aversion to brain surgery. (michaeljfox.org)
Stimulator16
- It covers a broad range of material that is presented by experts in each field, such as discography, percutaneous discectomy, vertebroplasty and balloon kyphoplasty, epidural steroid injections, selective nerve root blocks, autonomic nerve blocks, spinal stimulator implantation, and spine v- cular intervention. (springer.com)
- Preparation for placement of a permanent spinal cord stimulator usually necessitates a trial procedure, which allows both the SCS team and the subject to determine whether or not a permanent implant would provide substantial or adequate pain relief and improvements in QOL. (medscape.com)
- What Is A Spinal Cord Stimulator? (renotahoepain.com)
- however, for patients who don't respond to nonsurgical treatments, a spinal cord stimulator may be able to provide you with more effective relief. (renotahoepain.com)
- A spinal cord stimulator is a device that's implanted under the skin where it sends mild electrical currents to the spinal cord every time the patient experiences pain. (renotahoepain.com)
- These are only some of the conditions that can benefit from a spinal cord stimulator. (renotahoepain.com)
- A spinal cord stimulator is often recommended along with other treatment options such as physical therapy, rehabilitation, and relaxation techniques. (renotahoepain.com)
- By interfering with them using a spinal cord stimulator, you can reduce pain and improve your quality of life. (novowellnesscenter.com)
- To find out if you're a good candidate for a spinal cord stimulator, call either office in Aiken or Hilton Head Island, South Carolina, or request an appointment online today. (novowellnesscenter.com)
- A spinal cord stimulator is an electrical device that a surgeon implants under your skin. (novowellnesscenter.com)
- Novo Wellness implants your spinal cord stimulator during a surgery. (novowellnesscenter.com)
- With a spinal cord stimulator, you can reduce or even eliminate your need for pharmaceutical pain medications. (novowellnesscenter.com)
- For ideal results, Novo Wellness might suggest integrating a spinal cord stimulator into a comprehensive treatment plan that includes physical therapy, exercises, relaxation techniques, and other approaches to improve your mobility and functioning. (novowellnesscenter.com)
- What maintenance does my spinal cord stimulator require? (novowellnesscenter.com)
- Living with a spinal cord stimulator can significantly reduce your pain, but you must keep up on its maintenance and take some precautions with certain activities. (novowellnesscenter.com)
- A spinal cord stimulator can improve your quality of life by reducing pain and the need for pain medications. (novowellnesscenter.com)
Tumors1
- Intramedullary spinal cord tumors, both primary CNS and metastatic (especially renal cell carcinoma), can also bleed and lead to hematomyelia. (medscape.com)
Surrounding the brain and spinal cord1
- Membrane surrounding the brain and spinal cord ( meningitis ). (healthwise.net)
Injury6
- The most common cause of spinal cord hemorrhage is traumatic injury. (medscape.com)
- Predictors and outcomes of spinal cord injury following complex branched/fenestrated endovascular aortic repair in the US Aortic Research Consortium. (harvard.edu)
- Outcomes following thoracic endovascular aortic repair for blunt thoracic aortic injury stratified by Society for Vascular Surgery grade. (harvard.edu)
- Therefore, a sensory level to light touch may be absent unless both of these are involved (e.g., a complete injury that involves all spinal cord tracts). (emcrit.org)
- Remember that animals with paralysis may have a spinal cord injury and should be handled very gently. (lortsmith.com)
- There are many possible causes of paralysis, but is usually associated with an injury of the spinal cord or nerves supplying the limb. (lortsmith.com)
Lumbar spin1
- Hematomyelia more commonly involves the cervical rather than thoracic or lumbar spinal cord. (medscape.com)
Stroke2
- A neurotechnology that stimulates the spinal cord instantly improves arm and hand mobility, enabling people affected by moderate to severe stroke to conduct their normal daily activities more easily, report researchers from the University of Pittsburgh and Carnegie Mellon University today in Nature Medicine. (news-medical.net)
- Dementia in people who have risk factors or symptoms of a stroke is often vascular dementia. (msdmanuals.com)
Chronic7
- Generally, people affected by Paget's disease do not have any symptoms, at least in the initial stages of developing this chronic bone disorder, and it is interesting to note that it is often identified when the X-rays of the patient are taken for diagnosing other medical conditions. (herbs2000.com)
- Chronic diseases and conditions are serious threats to the population's health. (cdc.gov)
- Chronic diseases represent seven of the top ten causes of mortality in the U.S. and are major economic drivers underlying burgeoning national health costs. (cdc.gov)
- We propose a set of contributing factors and a model to help better understand the relationship of disability with chronic disease. (cdc.gov)
- Dramatic escalation in rates of chronic diseases and conditions make them a major public health problem in the U.S.1 and globally.2 We are beginning to recognize the major contribution that chronic diseases make to the poor health of people with disabilities. (cdc.gov)
- Among the most significant chronic diseases are heart disease, diabetes, cancer and respiratory problems.2 The major modifiable risks for these chronic diseases relate to lifestyle behaviors such as smoking, physical inactivity and poor nutrition, and excessive use of alcohol. (cdc.gov)
- This inclusion of disability as a chronic condition does not allow examination of the health risks posed by chronic diseases to people with pre-existing functional limitations. (cdc.gov)
Effect on the spinal cord2
- In such a case, one could suggest a more peripheral site of primary abnormality, with a secondary effect on the spinal cord. (ajnr.org)
- In addition, the patients may experience collapse of the vertebra or vascular changes that may have an effect on the spinal cord resulting in paraplegia. (herbs2000.com)
Autonomic1
- Autonomic nerves run within the grey matter, near the center of the cord. (emcrit.org)
Posterior spinal a4
- For perfusion, three longitudinal vessels form an anastomotic network that supplies the spinal cord: two posterior spinal arteries, and the anterior spinal artery. (medscape.com)
- The blood flow to the posterior spinal arteries originates from intradural vertebral arteries, which are from medullary segments of the posterior inferior cerebellar arteries and segmental radiculopial arteries. (medscape.com)
- The posterior spinal arteries give rise to the "vasocorona," which eventually branches into peripheral arteries and mainly supplies the white matter of the spinal cord. (medscape.com)
- Reduced blood flow to the spinal cord which is supplied by the anterior spinal artery and the paired posterior spinal arteries. (harvard.edu)
Nerves3
- Spinal nerves and corresponding sensory dermatomes are shown above. (emcrit.org)
- Nerves to the cervical cord are located closest to the middle of the cord, whereas nerves to the sacrum are located farthest towards the edges of the spinal cord. (emcrit.org)
- It includes the brain, the spinal cord, and all the nerves in the body. (healthwise.net)
Patients12
- Preoperative Spinal Drain Placement is Associated with Reduced Risk of Spinal Cord Ischemia in Patients Undergoing Thoracic Endovascular Aortic Repair for Aortic Dissection. (harvard.edu)
- Patients with partial cord involvement may fail to display a sensory level. (emcrit.org)
- Two patients did not undergo resection or transplantation and died of progressive disease. (stanford.edu)
- Following transplantation, 5 patients were alive at the end of the follow-up period and one died of recurrent disease. (stanford.edu)
- It is well recognized that patients with AIDS can present with a myelopathy unrelated to a tumor, opportunistic infection, or vascular disease. (ajnr.org)
- Despite the small number of patients in each of their MR and clinical categories, one can recognize a trend toward more striking MR-revealed changes (abnormal cord signal and spinal cord atrophy) found in the more severely affected patients. (ajnr.org)
- The increasing demand for vascular boots for patients with arterial thrombolytics is expected to drive market growth during the forecast period. (futuremarketinsights.com)
- Each year in the U.S., 5,000 patients receive a diagnosis of ALS, an incurable neurodegenerative disease that will likely kill them within two to five years. (news-medical.net)
- Patients affected by Paget's disease experience bone pain in the bones that have developed this condition. (herbs2000.com)
- Neurointerventional surgery provides a complete spectrum of minimally invasive services for the diagnosis and treatment of patients with vascular problems related to the brain and spinal cord. (ausrad.com)
- Patients with vascular TOS may require repair of veins and arteries. (brighamandwomens.org)
- Results: Both patients presented with an atypical intracranial SAH and were also found to have spinal SAH caused by a ruptured posterior spinal aneurysm. (elsevierpure.com)
Spine3
- See the MRI below showing spinal malformation of the thoracic spine. (medscape.com)
- Note that the spinal cord level doesn't line up precisely with the corresponding vertebrae, especially caudal to the thoracic spine. (emcrit.org)
- Lhermitte's sign (an electric-shock sensation elicited by neck flexion that runs down the spine and sometimes into the limbs) suggests involvement of the posterior columns of the cervical spinal cord. (emcrit.org)
Ischemic1
- Subcortical ischemic vascular cognitive impairment and dementia: Dementia results from tissue damage in the area of the brain under the cortex (the convoluted outer surface of the cerebrum, which is the largest part of the brain). (msdmanuals.com)
Artery7
- [ 4 ] These fistulas are created when a radiculomeningeal artery feeds directly into a radicular vein, usually near the spinal nerve root. (medscape.com)
- Multiple feeding vessels from the anterior spinal artery and/or the posterior spinal circulation typically supply these AVMs. (medscape.com)
- Blood flows from the anterior spinal artery into medullary branches of the intradural vertebral arteries, and subsequently into segmental radiculomedullary arteries. (medscape.com)
- Blood flow to the lower portion of the spinal cord (T8-L3) is supplied by a large radicular artery with somewhat variable positioning, termed the Artery of Adamkiewicz. (medscape.com)
- The central perfusion region receives blood supply from the anterior spinal artery, which forms the central sulcus artery and courses into the ventral median sulcus and supplies the grey matter of spinal cord. (medscape.com)
- Krishnan P, Banerjee TK, Saha M. Congestive myelopathy (Foix-Alajouanine Syndrome) due to intradural arteriovenous fistula of the filum terminale fed by anterior spinal artery: Case report and review of literature. (medscape.com)
- matter regions supplied by the posterior spinal artery. (medfriendly.com)
Ischemia6
- Ischemia results from mass effect and disruption of blood flow, which may cause infarction of the spinal cord. (medscape.com)
- Spinal Cord Ischemia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
- Prolonged ischemia may lead to INFARCTION of spinal cord tissue. (harvard.edu)
- This graph shows the total number of publications written about "Spinal Cord Ischemia" by people in Harvard Catalyst Profiles by year, and whether "Spinal Cord Ischemia" was a major or minor topic of these publication. (harvard.edu)
- Below are the most recent publications written about "Spinal Cord Ischemia" by people in Profiles. (harvard.edu)
- Intranasal administration of polysulfide prevents neurodegeneration in spinal cord and rescues mice from delayed paraplegia after spinal cord ischemia. (harvard.edu)
Dural6
- Spinal arterial dural fistulas commonly arise in an elderly population and are believed to be due to a traumatic occurrence. (medscape.com)
- Jellema K, Tijssen CC, van Gijn J. Spinal dural arteriovenous fistulas: a congestive myelopathy that initially mimics a peripheral nerve disorder. (medscape.com)
- Late diagnosis of spinal dural arteriovenous fistulas resulting in severe lower-extremity weakness: a case series. (medscape.com)
- Endovascular management of spinal dural arteriovenous fistulas. (medscape.com)
- Endovascular and surgical treatment of spinal dural arteriovenous fistulas. (medscape.com)
- Hessler C, Regelsberger J, Grzyska U, Illies T, Zeumer H, Westphal M. Therapeutic clues in spinal dural arteriovenous fistulas - a 30 year experience of 156 cases. (medscape.com)
Neurologic1
- Thus, a central spinal cord lesion may cause neurologic deficits in a descending order. (emcrit.org)
20231
- The vascular boot market is estimated to secure a valuation of US$ 1.1 billion in 2023 and is estimated to rise to US$ 1.5 billion by 2033. (futuremarketinsights.com)
Cervical1
- Photomicrograph of the cervical spinal cord region showing a thickened subarachnoid vein with a thrombotic occlusion (hematoxylin and eosin stain). (medscape.com)
Myelopathy4
- Spinal cord hemorrhage usually presents as sudden, painful myelopathy, which may reflect the anatomic level of the hemorrhage. (medscape.com)
- Although Chong et al, in this issue of the AJNR (page 1412), do not attempt to answer these questions, they describe the variable MR findings in the spinal cord in AIDS-associated myelopathy, and correlate these findings with the clinical status of the patient. (ajnr.org)
- Equally surprising is the finding that a patient with a mild myelopathy could have pronounced MR findings with cord atrophy and intrinsic spinal cord signal abnormalities. (ajnr.org)
- A strong association between HIV encephalopathy and AIDS-associated myelopathy would be reflected in some commonality of MR findings in the brain and spinal cord, namely varying degrees of atrophy, abnormal signal on T2-weighted images, and a lack of abnormal contrast enhancement. (ajnr.org)
Amyotrophic Lateral S5
- Researchers at the Francis Crick Institute and UCL have shown that hundreds of proteins and mRNA molecules are found in the wrong place in nerve cells affected by Motor Neuron Disease (MND), also known as Amyotrophic Lateral Sclerosis (ALS). (news-medical.net)
- Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a fatal motor neuron disease that causes people to gradually lose control of their muscles. (news-medical.net)
- Researchers at Nagoya University in Japan have discovered a receptor, sigma-1 receptor, and a protein, ATAD3A, that are associated with Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease. (news-medical.net)
- In virtually all persons with amyotrophic lateral sclerosis (ALS) and in up to half of all cases of Alzheimer's disease (AD) and frontotemporal dementia, a protein called TDP-43 is lost from its normal location in the nucleus of the cell. (news-medical.net)
- New research offers clues about the biology of cells in the spinal cord that die off in amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. (news-medical.net)
Venous3
- Note the thoracolumbar junction with an edematous spinal cord and dilated serpiginous intradural venous plexus. (medscape.com)
- This malformation consists of a tightly compacted group of arterial and venous vessels (nidus) inside a short segment of the spinal cord. (medscape.com)
- The pial surface and superficial regions of the spinal cord are drained by radial veins and the coronal venous plexus. (medscape.com)
Lesion2
- Evaluating for a sensory level using a pin to detect pain sensation is more sensitive to detect a spinal level originating from a lesion in the spinothalamic tract. (emcrit.org)
- Motor weakness may be used to evaluate the level of a spinal lesion that involves the corticospinal tract. (emcrit.org)
Nervous system2
- The brain and spinal cord (central nervous system). (healthwise.net)
- If the source of the disease is suspected to be in the nervous system, a sample of cerebrospinal fluid (CSF) will be taken for laboratory analysis. (wolvesdenranch.com)
Atherosclerosis1
- While it is established that cardiovascular disease (CVD) is typically associated with middle or old age, atherosclerosis often initiates in early childhood when deposits of cholesterol form fatty streaks in the intima of large arteries. (umc.edu)
Intramedullary1
- Summary of intramedullary spinal cord hemorrhage etiologies, with history and associated clues, common imaging findings, and representative management. (medscape.com)
Subarachnoid1
- Background: Approximately 1 % of cases of intracranial subarachnoid hemorrhage (SAH) are caused by spinal vascular pathologies. (elsevierpure.com)
Centers for Diseas6
- Centers for Disease Control and Prevention. (cdc.gov)
- The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. (cdc.gov)
- The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
- Read Carefully before Using The Public Health Service Act (Section 308 (d)) provides that the data collected by the National Center for Health Statistics (NCHS), Centers for Disease Control and Prevention (CDC), may be used only for the purpose of health statistical reporting and analysis. (cdc.gov)
- The NAMCS is a national probability sample survey conducted by the Division of Health Care Statistics, National Center for Health Statistics (NCHS), Centers for Disease Control and Prevention (CDC). (cdc.gov)
- The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention. (cdc.gov)
Infection4
- On the other hand, if no significant association between brain and spinal cord MR findings were present, it would be difficult to imply that an HIV infection of just the spinal cord were present. (ajnr.org)
- It is believed that a viral infection may possibly set off Paget's disease in individuals having inherited the propensity of the genes to develop this disease by possessing these specific genes. (herbs2000.com)
- The young adults (2-3 cm in length) enter the vascular system and are carried to the heart and pulmonary arteries, arriving as early as 70 days after infection. (capcvet.org)
- Monkeypox (mpox) is a disease caused by infection with Monkeypox virus (MPXV), an Orthopoxvirus (OPXV) in the same genus as Variola virus , which causes smallpox. (cdc.gov)
Hemorrhage3
- Hemorrhage affecting the spinal cord is rare. (medscape.com)
- Spinal cord hemorrhage can be divided based on etiology, into two types: (1) traumatic and (2) non-traumatic. (medscape.com)
- Hematomyelia is defined as the presence of a well-defined focus of hemorrhage within the spinal cord itself. (medscape.com)
Abnormal4
- Abnormal gait may be caused by diseases in different areas of the body. (medlineplus.gov)
- Alzheimer Disease Alzheimer disease is a progressive loss of mental function, characterized by degeneration of brain tissue, including loss of nerve cells, the accumulation of an abnormal protein called beta-amyloid. (msdmanuals.com)
- CAA is caused by accumulation of beta-amyloid (an abnormal protein) in blood vessels in brain, Most people with Alzheimer disease have CAA, but it also occurs in the brains of many healthy older people. (msdmanuals.com)
- Instability is defined by abnormal spinal alignment under physiologic conditions (loads) such as standing, walking, bending, or lifting. (bvsalud.org)
Implant1
- The news of the first BIOFLEX-I Pulsar-18 implant follows the recently presented 12-month results of the European 4EVER study , which investigated both the acute and long-term performance of 4F compatible devices from Biotronik in the lower limbs, or peripheral vascular procedures. (vascularnews.com)
Malformation1
- Spinal malformation. (medscape.com)
Arterial1
- The study will evaluate the safety and efficacy of the Astron and Pulsar stent families for the treatment of peripheral arterial disease. (vascularnews.com)
Tissue2
- The spinal cord is composed of neuronal pathways, glial tissue, and interwoven vascular structures that perfuse the spinal parenchyma. (medscape.com)
- Vascular dementia is loss of mental function due to destruction of brain tissue because its blood supply is reduced or blocked. (msdmanuals.com)
Treatments1
- Research at The University of Queensland could eventually help develop viable treatments - and ultimately a cure - for motor neuron disease (MND). (news-medical.net)
Surgery1
- Depending on the cause and severity of paralysis, your vet may prescribe some medication, give advice on strict cage rest and monitoring at home or recommend further diagnostic imaging like an MRI and possible spinal or orthopaedic surgery. (lortsmith.com)
Symptoms1
- It is worth mentioning here two main factors - the affected bones as well as the severity of the condition determine the symptoms of Paget's disease. (herbs2000.com)
Veins1
- Anterior and posterior median spinal veins drain the anterior and posterior regions of the spinal cord, respectively. (medscape.com)
Uncommon1
- This may be harder than it sounds, because spinal cord disease is uncommon and not generally high on our list of considerations. (emcrit.org)
Diagnosis1
- The first step towards diagnosis and therapy is recognizing that the patient has some sort of spinal cord pathology. (emcrit.org)