Predicting SA-I mechanoreceptor spike times with a skin-neuron model. (1/36)
(+info)Targeted depletion of Polo-like kinase (Plk) 1 through lentiviral shRNA or a small-molecule inhibitor causes mitotic catastrophe and induction of apoptosis in human melanoma cells. (2/36)
(+info)Do cephalopods communicate using polarized light reflections from their skin? (3/36)
(+info)MicroRNA-mediated control in the skin. (4/36)
(+info)Epithelialization in oral mucous wound healing in terms of energy metabolism. (5/36)
PURPOSE: The purpose of this study was to clarify the "healing capacity" of wounds of the oral mucosa in comparison to those of the skin, and to evaluate the wound healing mechanism of oral mucosa using a cytobiological approach from the aspect of energy metabolism in oral keratinocytes. MATERIALS AND METHODS: Samples of epidermal and oral keratinocytes collected at surgery and of cultured oral keratinocytes were used to analyze (1) by gas chromatography the composition of fatty acids (16:0, 18:2, 20:4) in the cell membranes of keratinocytes, (2) by immunohistochemical staining of GLUT-1 antibody and specific PAS staining the localization of glucose metabolism, and (3) by RT-PCR and Western blotting the expression of GLUT-1 mRNA and of protein in the keratinocytes of the basal and parabasal layers of each epithelial tissue. RESULTS: 1. The % composition of palmitic acid (16:0) was significantly higher in buccal mucosal keratinocytes (27.18+/-3.74%) and in the gingiva (23.00+/-1.40%) than in the epidermis (17.54+/-0.37%). 2. Immunohistochemical staining showed GLUT-1 protein in the skin to be expressed only in the bulge region of hair follicles and in the epidermal basal layer, and observed nearly throughout all epithelial cell layers in the oral mucosa. 3. PAS-positive cells were observed among differentiation-enhanced cells in the upper prickle layer in the oral mucosa. 4. The same results were obtained from RT-PCR and a Western blotting analysis. CONCLUSION: The present study demonstrated definite cytobiological evidence that the oral mucosa surpasses the skin in regard to its wound healing capacity. (+info)Recent advances on skin-resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti-aging and cancer therapies. (6/36)
(+info)Functional coupling between motor and sensory nerves through contraction of sphincters in the pudendal area of the female cat. (7/36)
(+info)Fingertip moisture is optimally modulated during object manipulation. (8/36)
(+info)Skin physiological processes refer to the biological functions and changes occurring within the skin, including barrier formation, pigmentation, thermoregulation, sensory perception, vitamin D synthesis, and wound healing, which are essential for maintaining skin homeostasis, protection, and overall health.
Skin physiological processes refer to the functions and changes that occur in the skin, which are necessary for its maintenance, repair, and regulation of body homeostasis. These processes include:
1. Barrier Function: The skin forms a physical barrier that protects the body from external factors such as microorganisms, chemicals, and UV radiation. It also helps to prevent water loss from the body.
2. Temperature Regulation: The skin plays a crucial role in regulating body temperature through sweat production and blood flow.
3. Immunological Function: The skin contains immune cells that help to protect the body against infection and disease.
4. Vitamin D Synthesis: The skin is able to synthesize vitamin D when exposed to sunlight.
5. Sensory Perception: The skin contains nerve endings that allow for the perception of touch, pressure, temperature, and pain.
6. Wound Healing: When the skin is injured, a complex series of physiological processes are initiated to repair the damage and restore the barrier function.
7. Excretion: The skin helps to eliminate waste products through sweat.
8. Hydration: The skin maintains hydration by regulating water loss and absorbing moisture from the environment.
9. Pigmentation: The production of melanin in the skin provides protection against UV radiation and determines skin color.
10. Growth and Differentiation: The skin constantly renews itself through a process of cell growth and differentiation, where stem cells in the basal layer divide and differentiate into mature skin cells that migrate to the surface and are eventually shed.
"Skin is the largest organ of the human body, acting as a protective barrier and involved in sensory perception, temperature regulation, and immune function."
In medical terms, the skin is the largest organ of the human body. It consists of two main layers: the epidermis (outer layer) and dermis (inner layer), as well as accessory structures like hair follicles, sweat glands, and oil glands. The skin plays a crucial role in protecting us from external factors such as bacteria, viruses, and environmental hazards, while also regulating body temperature and enabling the sense of touch.
Heat pen
... causing the skin to briefly heat up to 53 °C (local hyperthermia). The heat activates various physiological processes. For ... Due to the short application time, the skin is not damaged. The positive effect of the heat stick could be confirmed by a study ... by briefly heating the skin. The heat pen is available either as a pen-like device or as a USB-attachment for the smartphone. A ... The heated plate is brought into contact with the area of skin affected by the insect bite for 3 to 10 seconds, ...
Sweet potato storage
Physiological processes within the plant can contribute highly to spoilage. Natural transpiration causes water loss and results ... and skinning. Delicate skin and poor harvesting and handling techniques are the main cause of these problems. Damage to tubers ... Curing is a technique used to toughen the outer layer of skin (periderm). This protects against excessive moisture loss, ... Curing can toughen the skin and heal minor physical damage, while drying can reduce spoilage and inactivate metabolic ...
Olm
The pineal gland in Proteus probably possesses some control over the physiological processes. Behavioral experiments revealed ... The white skin color of the olm retains the ability to produce melanin, and will gradually turn dark when exposed to light; in ... It may be a variant of the word Molch 'salamander'. It is also called the "human fish" by locals because of its fleshy skin ... Self-purification processes in the underground waters are not completely understood, but they are quite different from those in ...
Wound healing
Examples of physiological regeneration are the continual replacement of cells of the skin and repair of the endometrium after ... becoming longer and flatter and extending cellular processes like lamellipodia and wide processes that look like ruffles. Actin ... After the repair process has been completed, there is a loss in the structure or function of the injured tissue. In this type ... The wound-healing process is not only complex but fragile, and it is susceptible to interruption or failure leading to the ...
Regeneration in humans
Examples of physiological regeneration are the continual replacement of cells of the skin and repair of the endometrium after ... After the repair process has been completed, the structure and function of the injured tissue are completely normal. This type ... Joshua Tam (2013). "Fractional Skin Harvesting: Autologous Skin Grafting without Donor-site Morbidity". Plastic and ... Skin tissue can be regenerated in vivo or in vitro. Other organs and body parts that have been procured to regenerate include: ...
Regeneration (biology)
Examples of physiological regeneration are the continual replacement of cells of the skin and repair of the endometrium after ... Within two weeks of skin wounding, mucus is secreted into the wound and this initiates the healing process. One study showed ... Examples of physiological regeneration in mammals include epithelial renewal (e.g., skin and intestinal tract), red blood cell ... identified 36 genes differentiating the healing process between MRL mice and other mice. Study of the regenerative process in ...
Peripolesis
... is thought to be a physiological mechanism involved in regulating some processes of immune response. It was ... Sharp, J. A.; Burwell, R. G. (1960-11-05). "Interaction ('Peripolesis') of Macrophages and Lymphocytes after Skin Homografting ... Peripolesis is the process in which a cell attaches itself to another cell. This is differentiated from emperipolesis, which is ... observed between lymphocytes and macrophages following skin grafts between subjects, and after immune challenge with antigens. ...
Gastrodermis
It is composed of specialized cells responsible for several vital physiological processes. The term is also used for the ... Gastrodermis (From Ancient Greek: γαστήρ, gastḗr, "stomach"; δέρμα, dérma, "skin") is the inner layer of cells that serves as a ... which involves the exchange of oxygen and carbon dioxide through the skin. The gastrodermis contains specialised cells called ...
Diabetic foot ulcer
But in some cases, certain disorders or physiological insult disturbs the wound healing process. Diabetes mellitus is one such ... effects on the skin: skin - and the soft tissues immediately underneath the skin - undergo greater compression and shear ... The dermis lies below the epidermis, and these two layers are collectively known as the skin. Dermal skin is primarily a ... The process is activated, though perhaps not exclusively, by cells responding to fragments of damaged ECM, and the repairs are ...
Vasodilation
The opposite physiological process is vasoconstriction. These processes are naturally modulated by local paracrine agents from ... this process diverts the flow of heated blood to the skin of the animal, where heat can be more easily released to the ... The process is the opposite of vasoconstriction, which is the narrowing of blood vessels. When blood vessels dilate, the flow ... The response may be intrinsic (due to local processes in the surrounding tissue) or extrinsic (due to hormones or the nervous ...
Physioeconomics
Physiological parameters, such as skin conductance, provides additional, objective measurements that allow a deeper insight ... into the decision making process. Particularly in the study of markets and negotiations, understanding the behavior and motives ... They review studies on a variety of physiological measures, including heart rate, skin conductance, and facial expressions. ... The term has also been used by Philip M. Parker in his book Physioeconomics to refer to his theory of the physiological basis ...
Neuroergonomics
Psychophysiological measures are physiological measures (blood, heart rate, skin conductance, etc.) which change as part of ... When the user engages in a specific mental activity, it generates a unique brain electrical potential that is processed and ... The goal of merging these two fields is to use the startling discoveries of human brain and physiological functioning both to ... Driving requires the integration of multiple cognitive processes, which can be studied separately if the right kinds of tools ...
Umbilical granuloma
An umbilical granuloma is a physiological response which surpasses the normal processes of skin restoration following umbilical ... Once the skin lesion is formed, there is an excess of fibroblast production. These fibroblasts, or connective tissue cells, are ... It may appear in the first few weeks of newborn infants during the healing process of the umbilical cord due to an umbilical ... The surrounding skin of the infant's umbilicus site will appear normal. Umbilical granulomas can become entry points for ...
Wearable technology
These wearables are mounted directly onto the skin to continuously monitor physiological and metabolic processes, both dermal ... Properties of epidermal electronics mirror those of skin to allow them to perform in this same way. Like skin, epidermal ... The significance of epidermal electronics involves their mechanical properties, which resemble those of skin. The skin can be ... Instead, it lies far beyond just a few things and rather is deeply connected to a variety of physiological and biochemical ...
Affective computing
The four main physiological signs that are usually analyzed are blood volume pulse, galvanic skin response, facial ... The process of speech/text affect detection requires the creation of a reliable database, knowledge base, or vector space model ... Other sensors detect emotional cues by directly measuring physiological data, such as skin temperature and galvanic resistance ... Skin conductance is often measured using two small silver-silver chloride electrodes placed somewhere on the skin and applying ...
Wound healing assay
Cell migration plays a huge role in re-epithelialization of the skin and so the study of cell migration can provide ... The scratch assay is a great tool to study cell migration since this mechanism is involved in many different physiological ... Cell migration is also fundamental in developmental processes such as gastrulation and organogenesis. Cell migration is also ...
Post-harvest losses (vegetables)
Skin blemishes may lower the sale price but do not render a fruit or vegetable inedible. Fungal and bacterial diseases are ... Increase in normal physiological changes can be caused by high temperature, low atmospheric humidity and physical injury. Such ... There is also a wide range of post-harvest technologies that can be adopted to improve losses throughout the process of pre- ... Potatoes, on the other hand, have a thick skin with few pores. But whatever the product, to extend shelf or storage life the ...
Antioxidative stress
... and physiological alterations (especially of the skin). Many foods contain antioxidant content, while numerous dietary ... pathogenic response processes. Serious health conditions can result if these processes are chronically unbalanced, ranging from ... Disrupting these natural processes by use of antioxidants may have additional undesired results beyond stimulating disease ... A diet rich in anti-oxidants could allow for skin alterations such as acute acne or chronic non-infectious lesions, especially ...
UVB-induced apoptosis
Some studies have shown that exercise accelerates this process. Apoptosis is a physiological process, that promotes the active ... to reach more deep layers skin and act on keratinocytes of the deep-lying basal layer of the epidermis of the skin. The ability ... but the role of UV-induced apoptosis of skin keratinocytes in the development of UV erythema (hyperemia, redness) of the skin ... Keratinocytes of the skin (regardless of UVR exposure) are in a state of programmed apoptosis, during which the keratinocytes ...
Chromatophore
This process, often used as a type of camouflage, is called physiological colour change or metachrosis. Cephalopods, such as ... These hormones may also be generated in a paracrine fashion by cells in the skin. At the surface of the melanophore, the ... This process, known as physiological colour change, is most widely studied in melanophores, since melanin is the darkest and ... It has been demonstrated that the process can be under hormonal or neuronal control or both and for many species of bony fishes ...
Automated Pain Recognition
... pain almost always initiates autonomic nervous processes that are reflected measurably in various physiological signals. ... Measurements can include electrodermal activity (EDA, also skin conductance), electromyography (EMG), electrocardiogram (ECG), ... Physiological signals are mainly recorded using special non-invasive surface electrodes (for EDA, EMG, ECG, and EEG), a blood ... During this process, modalities from different signal sources are merged to generate new or more precise knowledge.[citation ...
Biofeedback
... processes. The definition reads: Biofeedback is a process that enables an individual to learn how to change physiological ... An electrodermograph (EDG) measures skin electrical activity directly (skin conductance and skin potential) and indirectly ( ... In skin resistance, also called galvanic skin response (GSR), an electrodermograph imposes a current across the skin and ... Some of the processes that can be controlled include brainwaves, muscle tone, skin conductance, heart rate and pain perception ...
Amorphosynthesis
In research by Denny-Brown and Banker, a disturbance in the physiological process of perceiving somatic sensations was termed ... Sensory receptors that are spread throughout the body [skin, organs, muscles, etc.] send sensory input signals to the cortex ... Thus, the left and right cerebral hemispheres exhibit redundant processing to the right-side of the body and a lesion to the ... Brain areas in the parietal lobes play an integral role in processing and interpreting somatic sensations from the body or ...
Somatosensory amplification
The cognitive-emotional process may be the outcome of the sensory process, leading to many criticisms towards this ... It is unclear whether persons with SSA have a truly increased physiological sensitivity to bodily sensations. One study ... or dry skin; 3) the visceral and somatic concomitants of intense affect, such as the sympathetic arousal accompanying anxiety; ... This process may remain subconscious, making the individual unable to detect and describe it, linking SSA to alexithymia. ...
Shortness of breath
... the skin and the joints. Different physiological pathways may lead to shortness of breath including via ASIC chemoreceptors, ... and central information processing. It is believed the central processing in the brain compares the afferent and efferent ... Acute shortness of breath is usually connected with sudden physiological changes, such as laryngeal edema, bronchospasm, ...
TRPV3
The TRPV3 channel has wide tissue expression that is especially high in the skin (keratinocytes) but also in the brain. It ... The TRPV3 protein belongs to a family of nonselective cation channels that function in a variety of processes, including ... and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C ... Xu H, Delling M, Jun JC, Clapham DE (2006). "Oregano, thyme and clove-derived flavors and skin sensitizers activate specific ...
Thermal neutral zone
Physiological mechanisms: The skin has a huge capacity to accept blood flow resulting in a range of 1ml/100g of skin/min, to ... These passive processes determine the TNZ, as negligible work is done to redirect blood to the peripheries or the core. ... In fact, skin can survive for long periods of time (hours) with sub-physiological blood flow and oxygenation, and, as long as ... In short, the skin must be able to get rid of 100 watts of heat in relatively warm environments, but also ensure that it does ...
LC4MP
A second set of methodological tools involves physiological measures such as heart rate, galvanic skin responses (sweating) or ... Watching TV involves a number of simultaneous cognitive processes. TV viewing often requires people to engage in processing ... Information retrieval is conceptualized as the third fundamental conceptual sub process of information processing, and it is a ... The most fundamental assumptions of information processing are the three dimensions of cognitive processing. The three ...
Self-healing
... may refer to automatic, homeostatic processes of the body that are controlled by physiological mechanisms inherent ... Such as the regeneration of the skin after a cut or scrape, or of an entire limb. The injured party (the living body) repairs ... Such a process encounters mixed fortunes due to its amateur nature, although self-motivation is a major asset. The value of ... The process can be helped and accelerated with introspection techniques such as Meditation. Self-healing is the ultimate phase ...
LED tattoo
This process is aided when saline solution is added, helping the silicon mold to the shape of the skin. Silk dissolves away ... LED tattoos would not interfere with normal physiological processes. The U.S. Food and Drug Administration (FDA) have approved ... "LED Tattoos: Human skin as lighted signs." Tuan, Mai. "Get Ready for Health Monitoring LED implants". Retrieved 13 August 2014 ... "The Illustrated Man: How LED Tattoos Could Make Your Skin a Screen." Wired 20 Nov 2009 Fiorenzo, Omenetto. "Silk, the ancient ...
