Plant tumors. Medical search

A localized proliferation of plant tissue forming a swelling or outgrowth, commonly with a characteristic shape and unlike any organ of the normal plant. Plant tumors or galls usually form in response to the action of a pathogen or a pest. (Holliday, P., A Dictionary of Plant Pathology, 1989, p330)

A species of gram-negative, aerobic bacteria isolated from soil and the stems, leafs, and roots of plants. Some biotypes are pathogenic and cause the formation of PLANT TUMORS in a wide variety of higher plants. The species is a major research tool in biotechnology.

A genus of gram-negative, aerobic, rod-shaped bacteria that activate PLANT ROOT NODULATION in leguminous plants. Members of this genus are nitrogen-fixing and common soil inhabitants.

PLANTS, or their progeny, whose GENOME has been altered by GENETIC ENGINEERING.

Expanded structures, usually green, of vascular plants, characteristically consisting of a bladelike expansion attached to a stem, and functioning as the principal organ of photosynthesis and transpiration. (American Heritage Dictionary, 2d ed)

Proteins found in plants (flowers, herbs, shrubs, trees, etc.). The concept does not include proteins found in vegetables for which VEGETABLE PROTEINS is available.

The usually underground portions of a plant that serve as support, store food, and through which water and mineral nutrients enter the plant. (From American Heritage Dictionary, 1982; Concise Dictionary of Biology, 1990)

The functional hereditary units of PLANTS.

Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.

New immature growth of a plant including stem, leaves, tips of branches, and SEEDLINGS.

Plants whose roots, leaves, seeds, bark, or other constituent parts possess therapeutic, tonic, purgative, curative or other pharmacologic attributes, when administered to man or animals.

Deoxyribonucleic acid that makes up the genetic material of plants.

Processes orchestrated or driven by a plethora of genes, plant hormones, and inherent biological timing mechanisms facilitated by secondary molecules, which result in the systematic transformation of plants and plant parts, from one stage of maturity to another.

Plants or plant parts which are harmful to man or other animals.

Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.

Molecular markers and cell cycle inhibitors show the importance of cell cycle progression in nematode-induced galls and syncytia. (1/273)

Root knot and cyst nematodes induce large multinucleated cells, designated giant cells and syncytia, respectively, in plant roots. We have used molecular markers to study cell cycle progression in these specialized feeding cells. In situ hybridization with two cyclin-dependent kinases and two cyclins showed that these genes were induced very early in galls and syncytia and that the feeding cells progressed through the G2 phase. By using cell cycle blockers, DNA synthesis and progression through the G2 phase, or mitosis, were shown to be essential for gall and syncytium establishment. When mitosis was blocked, further gall development was arrested. This result demonstrates that cycles of endoreduplication or other methods of DNA amplification are insufficient to drive giant cell expansion. On the other hand, syncytium development was much less affected by a mitotic block; however, syncytium expansion was inhibited. (+info)

Ti plasmids from Agrobacterium characterize rootstock clones that initiated a spread of crown gall disease in Mediterranean countries. (2/273)

Crown gall caused by Agrobacterium is one of the predominant diseases encountered in rose cultures. However, our current knowledge of the bacterial strains that invade rose plants and the way in which they spread is limited. Here, we describe the integrated physiological and molecular analyses of 30 Agrobacterium isolates obtained from crown gall tumors and of several reference strains. Characterization was based on the determination of the biovar, analysis of 16S ribosomal DNA restriction fragment length polymorphisms by PCR (PCR-RFLP), elucidation of the opine type, and PCR-RFLP analysis of genes involved in virulence and oncogenesis. This study led to the classification of rose isolates into seven groups with common chromosome characteristics and seven groups with common Ti plasmid characteristics. Altogether, the rose isolates formed 14 independent groups, with no specific association of plasmid- and chromosome-encoded traits. The predominant Ti plasmid characteristic was that 16 of the isolates induced the production of the uncommon opine succinamopine, while the other 14 were nopaline-producing isolates. With the exception of one, all succinamopine Ti plasmids belonged to the same plasmid group. Conversely, the nopaline Ti plasmids belonged to five groups, one of these containing seven isolates. We showed that outbreaks of disease provoked by the succinamopine-producing isolates in different countries and nurseries concurred with a common origin of specific rootstock clones. Similarly, groups of nopaline-producing isolates were associated with particular rootstock clones. These results strongly suggest that the causal agent of crown gall disease in rose plants is transmitted via rootstock material. (+info)

Cell-division factors from Vinca rosca L. crown gall tumor tissue. (3/273)

A cell-division factor has been precipitated from extracts of cultured Vinca rosea L. crown gall tumor tissue by using the mercuric acetate procedure previously employed by Wood and colleagues to obtain their "cytokinesin I." On the basis of its mass spectrum, ultraviolet light absorbancy spectra, solubilities, chromatographic migration values, and growth activity, the factor is ribosyl-trans-zeatin, that is, 6-(4-hydroxy-3-methyl-trans-2-butenylamino)-9-beta-D-ribofuranosylpurine. Ribosylzeatin has now been isolated from tumor tissue by four experimental techniques; any possibility that it is an artifact seems to have been eliminated. Contrary to the report by Wood and colleagues, synthetic ribosylzeatin is precipitated from an aqueous solution by mercuric acetate, provided the complete precipitation procedure is utilized. These facts and others discussed strongly support our suggestion that ribosylzeatin was present in the preparation ("cytokinesin I") examined by Wood and colleagues in several biological assays. The reasons advanced by Wood and others for rejecting this suggestion have been found either not to be pertinent to the question or to have insufficient experimental bases. (+info)

An inherited "neoplasm" in fungus. (4/273)

An abnormal growth form in the fungus Schizophyllum commune is described that interferes with the development of reproductive structures. The abnormality, which takes the form of relatively large, compact, hemispherical bodies, depends on a dominant Mendelian gene, mound, for its expression. When mound is expressed in a mycelium that has the potential to form fruiting bodies, the fruiting response is affected and the effect is variable within a replicate series: fruiting bodies may be normal or abnormal, abort at various stages, or not develop at all. Occasionally, fruit bodies are overgrown and are completely enveloped by the hemispherical bodies. When hyphae from hemispherical bodies are subcultured, a seemingly normal mycelium forms that eventually differentiates hemispherical structures, but the ability to form fruiting bodies in not expressed. Continuous mycelial subculture has shown this loss of fruiting expression to be a permanent transformation, which is demonstrated to be a characteristic of hemispherical bodies. (+info)

Suppression of the neoplastic state with the acquisition of specialized functions in cells, tissues, and organs of crown gall teratomas of tobacco. (5/273)

The neoplastic state in cells of tissues and organs that develop from cloned lines of crown gall teratomas of tobacco may be completely but reversibly suppressed. Stems and leaves found on teratoma shoots may appear morphologically normal and such organs contain all of the specialized cell types and are histologically and functionally indistinguishable from those found in normal tobacco shoots of comparable age. When however, specialized cells of several different kinds that are present in stems and leaves of the teratomas are excised from the plant and grown on a basic culture medium they again assume their neoplastic properties. The results of this study indicate that the morphogenetic factors and mechanisms that govern so precisely growth, cellular differentiation, and organogenesis during the normal course of development can completely suppress the tumorous state, leading to the formation of cells, tissues, and organs that appear normal in every respect but are, in fact, inherently neoplastic. Whether the normal or tumor phenotype is expressed appears to depend on the activation or repression of select biosynthetic systems, one of which, the auxin sytems, has been identified here. (+info)

High relatedness and inbreeding at the origin of eusociality in gall-inducing thrips. (6/273)

Within the haplodiploid eusocial gall-inducing thrips, a species-level phylogeny combined with genetic data for five eusocial species enables an inference of levels of relatedness and inbreeding values for lineages at the origin of eusociality. Character optimization using data from five eusocial species indicates that the lineage or lineages where eusociality is inferred to have originated exhibit relatedness of 0.64-0.92, and F(IS) of 0.33-0.64. The high inbreeding coefficients found in these eusocial thrips have increased relatedness among and within both sexes and have reduced the haplodiploidy-induced relatedness asymmetries [Hamilton, W. D. (1964) J. Theor. Biol. 7, 1-52]. These results indicate that unusually high relatedness is associated with the origin of eusociality, and they suggest a role for inbreeding in the evolution of bisexual helping. (+info)

Bruchins: insect-derived plant regulators that stimulate neoplasm formation. (7/273)

Pea weevil (Bruchus pisorum L.) oviposition on pods of specific genetic lines of pea (Pisum sativum L.) stimulates cell division at the sites of egg attachment. As a result, tumor-like growths of undifferentiated cells (neoplasms) develop beneath the egg. These neoplasms impede larval entry into the pod. This unique form of induced resistance is conditioned by the Np allele and mediated by a recently discovered class of natural products that we have identified from both cowpea weevil (Callosobruchus maculatus F.) and pea weevil. These compounds, which we refer to as "bruchins," are long-chain alpha,omega-diols, esterified at one or both oxygens with 3-hydroxypropanoic acid. Bruchins are potent plant regulators, with application of as little as 1 fmol (0.5 pg) causing neoplastic growth on pods of all of the pea lines tested. The bruchins are, to our knowledge, the first natural products discovered with the ability to induce neoplasm formation when applied to intact plants. (+info)

Leifsonia poae gen. nov., sp. nov., isolated from nematode galls on Poa annua, and reclassification of 'Corynebacterium aquaticum' Leifson 1962 as Leifsonia aquatica (ex Leifson 1962) gen. nov., nom. rev., comb. nov. and Clavibacter xyli Davis et al. 1984 with two subspecies as Leifsonia xyli (Davis et al. 1984) gen. nov., comb. nov. (8/273)

The new genus Leifsonia gen. nov. with two new species, Leifsonia poae sp. nov. (type strain VKM Ac-1401T) and Leifsonia aquatica (ex Leifson 1962) nom. rev., comb. nov. (the type species, with VKM Ac-1400T = DSM 20146T = JCM 1368T as type strain), is proposed to accommodate bacteria found in Poa annua root gall, induced by the nematode Subanguina radicicola, and 'Corynebacterium aquaticum' Leifson 1962. Further, it is proposed to reclassify Clavibacter xyli Davis et al. 1984 with two subspecies in the new genus as Leifsonia xyli (Davis et al. 1984) comb. nov., Leifsonia xyli subsp. xyli (Davis et al. 1984) comb. nov. and Leifsonia xyli subsp. cynodontis (Davis et al. 1984) comb. nov. Members of the proposed genus are characterized by coryneform morphology, peptidoglycans based upon 2,4-diaminobutyric acid, the major menaquinone MK-11, phosphatidylglycerol and diphosphatidylglycerol as principal phospholipids, the high content of anteiso- and iso-branched saturated fatty acids, and a DNA G+C base composition of 66-73 mol%. They form a distinct phylogenetic branch attached to the line of descent of Agromyces spp. The new and reclassified species of the new genus clearly differ from each other phylogenetically and phenetically and can be recognized by their morphologies, the cell wall sugar composition, the requirement of complex media for growth, and numerous physiological characteristics, including the oxidase reaction. (+info)

A plant tumor, also known as a gall or neoplasm, is an abnormal growth that occurs in plants. These growths can be caused by various factors such as genetic mutations, bacterial or viral infections, and physical injuries. However, the most well-known cause of plant tumors are crown galls, which are induced by the bacterium Agrobacterium tumefaciens.

When this bacterium infects a plant through a wound, it transfers a portion of its DNA (T-DNA) into the plant's cells. The T-DNA contains genes that encode enzymes responsible for the production of auxins and cytokinins, two types of plant hormones that promote cell division and growth. As a result, the infected plant cells start to divide uncontrollably, leading to the formation of a tumor-like growth.

Plant tumors can vary in size and appearance, ranging from small bumps to large, disfigured growths. While they are not typically harmful to the plant, they can reduce its aesthetic value and economic productivity. In some cases, plant tumors may also provide a habitat for pests and diseases, which can further harm the plant.

'Agrobacterium tumefaciens' is a gram-negative, soil-dwelling bacterium that is known for its ability to cause plant tumors or crown galls. It does this through the transfer and integration of a segment of DNA called the Ti (Tumor-inducing) plasmid into the plant's genome. This transferred DNA includes genes that encode enzymes for the production of opines, which serve as a nutrient source for the bacterium, and genes that cause unregulated plant cell growth leading to tumor formation.

This unique ability of 'Agrobacterium tumefaciens' to transfer and integrate foreign DNA into plants has been exploited in genetic engineering to create transgenic plants with desired traits. The Ti plasmid is often used as a vector to introduce new genes into the plant genome, making it an essential tool in plant biotechnology.

Rhizobium is not a medical term, but rather a term used in microbiology and agriculture. It refers to a genus of gram-negative bacteria that can fix nitrogen from the atmosphere into ammonia, which can then be used by plants as a nutrient. These bacteria live in the root nodules of leguminous plants (such as beans, peas, and clover) and form a symbiotic relationship with them.

The host plant provides Rhizobium with carbon sources and a protected environment within the root nodule, while the bacteria provide the plant with fixed nitrogen. This mutualistic interaction plays a crucial role in maintaining soil fertility and promoting plant growth.

While Rhizobium itself is not directly related to human health or medicine, understanding its symbiotic relationship with plants can have implications for agricultural practices, sustainable farming, and global food security.

Genetically modified plants (GMPs) are plants that have had their DNA altered through genetic engineering techniques to exhibit desired traits. These modifications can be made to enhance certain characteristics such as increased resistance to pests, improved tolerance to environmental stresses like drought or salinity, or enhanced nutritional content. The process often involves introducing genes from other organisms, such as bacteria or viruses, into the plant's genome. Examples of GMPs include Bt cotton, which has a gene from the bacterium Bacillus thuringiensis that makes it resistant to certain pests, and golden rice, which is engineered to contain higher levels of beta-carotene, a precursor to vitamin A. It's important to note that genetically modified plants are subject to rigorous testing and regulation to ensure their safety for human consumption and environmental impact before they are approved for commercial use.

I believe there may be a slight misunderstanding in your question. "Plant leaves" are not a medical term, but rather a general biological term referring to a specific organ found in plants.

Leaves are organs that are typically flat and broad, and they are the primary site of photosynthesis in most plants. They are usually green due to the presence of chlorophyll, which is essential for capturing sunlight and converting it into chemical energy through photosynthesis.

While leaves do not have a direct medical definition, understanding their structure and function can be important in various medical fields, such as pharmacognosy (the study of medicinal plants) or environmental health. For example, certain plant leaves may contain bioactive compounds that have therapeutic potential, while others may produce allergens or toxins that can impact human health.

"Plant proteins" refer to the proteins that are derived from plant sources. These can include proteins from legumes such as beans, lentils, and peas, as well as proteins from grains like wheat, rice, and corn. Other sources of plant proteins include nuts, seeds, and vegetables.

Plant proteins are made up of individual amino acids, which are the building blocks of protein. While animal-based proteins typically contain all of the essential amino acids that the body needs to function properly, many plant-based proteins may be lacking in one or more of these essential amino acids. However, by consuming a variety of plant-based foods throughout the day, it is possible to get all of the essential amino acids that the body needs from plant sources alone.

Plant proteins are often lower in calories and saturated fat than animal proteins, making them a popular choice for those following a vegetarian or vegan diet, as well as those looking to maintain a healthy weight or reduce their risk of chronic diseases such as heart disease and cancer. Additionally, plant proteins have been shown to have a number of health benefits, including improving gut health, reducing inflammation, and supporting muscle growth and repair.

A plant root is not a medical term per se, but it is a term from botany, which is the study of plants. However, I can certainly provide a definition for you.

Plant roots are the underground organs of a plant that typically grow downward into the soil. They serve several important functions, including:

1. Anchorage: Roots help to stabilize the plant and keep it upright in the ground.
2. Absorption: Roots absorb water and nutrients from the soil, which are essential for the plant's growth and development.
3. Conduction: Roots conduct water and nutrients up to the above-ground parts of the plant, such as the stem and leaves.
4. Vegetative reproduction: Some plants can reproduce vegetatively through their roots, producing new plants from root fragments or specialized structures called rhizomes or tubers.

Roots are composed of several different tissues, including the epidermis, cortex, endodermis, and vascular tissue. The epidermis is the outermost layer of the root, which secretes a waxy substance called suberin that helps to prevent water loss. The cortex is the middle layer of the root, which contains cells that store carbohydrates and other nutrients. The endodermis is a thin layer of cells that surrounds the vascular tissue and regulates the movement of water and solutes into and out of the root. The vascular tissue consists of xylem and phloem, which transport water and nutrients throughout the plant.

A gene in plants, like in other organisms, is a hereditary unit that carries genetic information from one generation to the next. It is a segment of DNA (deoxyribonucleic acid) that contains the instructions for the development and function of an organism. Genes in plants determine various traits such as flower color, plant height, resistance to diseases, and many others. They are responsible for encoding proteins and RNA molecules that play crucial roles in the growth, development, and reproduction of plants. Plant genes can be manipulated through traditional breeding methods or genetic engineering techniques to improve crop yield, enhance disease resistance, and increase nutritional value.

A plant extract is a preparation containing chemical constituents that have been extracted from a plant using a solvent. The resulting extract may contain a single compound or a mixture of several compounds, depending on the extraction process and the specific plant material used. These extracts are often used in various industries including pharmaceuticals, nutraceuticals, cosmetics, and food and beverage, due to their potential therapeutic or beneficial properties. The composition of plant extracts can vary widely, and it is important to ensure their quality, safety, and efficacy before use in any application.

A medical definition for "plant shoots" may not be readily available, as the term is primarily used in botany and horticulture. However, I can provide you with a general definition:

Plant shoots refer to the above-ground portion of a plant, which typically includes structures like stems, leaves, flowers, and buds. Shoots originate from the seed or the growing tip of the plant and are responsible for photosynthesis, nutrient absorption, and reproduction. In some contexts, "plant shoots" might also refer to new growth that emerges from an existing plant, such as when a leaf or stem sprouts a new branch or flower.

Medicinal plants are defined as those plants that contain naturally occurring chemical compounds which can be used for therapeutic purposes, either directly or indirectly. These plants have been used for centuries in various traditional systems of medicine, such as Ayurveda, Chinese medicine, and Native American medicine, to prevent or treat various health conditions.

Medicinal plants contain a wide variety of bioactive compounds, including alkaloids, flavonoids, tannins, terpenes, and saponins, among others. These compounds have been found to possess various pharmacological properties, such as anti-inflammatory, analgesic, antimicrobial, antioxidant, and anticancer activities.

Medicinal plants can be used in various forms, including whole plant material, extracts, essential oils, and isolated compounds. They can be administered through different routes, such as oral, topical, or respiratory, depending on the desired therapeutic effect.

It is important to note that while medicinal plants have been used safely and effectively for centuries, they should be used with caution and under the guidance of a healthcare professional. Some medicinal plants can interact with prescription medications or have adverse effects if used inappropriately.

DNA, or deoxyribonucleic acid, is the genetic material present in the cells of all living organisms, including plants. In plants, DNA is located in the nucleus of a cell, as well as in chloroplasts and mitochondria. Plant DNA contains the instructions for the development, growth, and function of the plant, and is passed down from one generation to the next through the process of reproduction.

The structure of DNA is a double helix, formed by two strands of nucleotides that are linked together by hydrogen bonds. Each nucleotide contains a sugar molecule (deoxyribose), a phosphate group, and a nitrogenous base. There are four types of nitrogenous bases in DNA: adenine (A), guanine (G), cytosine (C), and thymine (T). Adenine pairs with thymine, and guanine pairs with cytosine, forming the rungs of the ladder that make up the double helix.

The genetic information in DNA is encoded in the sequence of these nitrogenous bases. Large sequences of bases form genes, which provide the instructions for the production of proteins. The process of gene expression involves transcribing the DNA sequence into a complementary RNA molecule, which is then translated into a protein.

Plant DNA is similar to animal DNA in many ways, but there are also some differences. For example, plant DNA contains a higher proportion of repetitive sequences and transposable elements, which are mobile genetic elements that can move around the genome and cause mutations. Additionally, plant cells have cell walls and chloroplasts, which are not present in animal cells, and these structures contain their own DNA.

'Plant development' is not a term typically used in medical definitions, as it is more commonly used in the field of botany to describe the growth and differentiation of plant cells, tissues, and organs over time. However, in a broader context, plant development can be defined as the series of changes and processes that occur from the fertilization of a plant seed to the formation of a mature plant, including germination, emergence, organ formation, growth, and reproduction.

In medicine, terms related to plant development may include "phytotherapy" or "herbal medicine," which refer to the use of plants or plant extracts as medicinal treatments for various health conditions. The study of how these plants develop and produce their active compounds is an important area of research in pharmacology and natural products chemistry.

'Toxic plants' refer to those species of plants that contain toxic substances capable of causing harmful effects or adverse health reactions in humans and animals when ingested, touched, or inhaled. These toxins can cause a range of symptoms from mild irritation to serious conditions such as organ failure, paralysis, or even death depending on the plant, the amount consumed, and the individual's sensitivity to the toxin.

Toxic plants may contain various types of toxins, including alkaloids, glycosides, proteins, resinous substances, and essential oils. Some common examples of toxic plants include poison ivy, poison oak, nightshade, hemlock, oleander, castor bean, and foxglove. It is important to note that some parts of a plant may be toxic while others are not, and the toxicity can also vary depending on the stage of growth or environmental conditions.

If you suspect exposure to a toxic plant, it is essential to seek medical attention immediately and, if possible, bring a sample of the plant for identification.

Tumor markers are substances that can be found in the body and their presence can indicate the presence of certain types of cancer or other conditions. Biological tumor markers refer to those substances that are produced by cancer cells or by other cells in response to cancer or certain benign (non-cancerous) conditions. These markers can be found in various bodily fluids such as blood, urine, or tissue samples.

Examples of biological tumor markers include:

1. Proteins: Some tumor markers are proteins that are produced by cancer cells or by other cells in response to the presence of cancer. For example, prostate-specific antigen (PSA) is a protein produced by normal prostate cells and in higher amounts by prostate cancer cells.
2. Genetic material: Tumor markers can also include genetic material such as DNA, RNA, or microRNA that are shed by cancer cells into bodily fluids. For example, circulating tumor DNA (ctDNA) is genetic material from cancer cells that can be found in the bloodstream.
3. Metabolites: Tumor markers can also include metabolic products produced by cancer cells or by other cells in response to cancer. For example, lactate dehydrogenase (LDH) is an enzyme that is released into the bloodstream when cancer cells break down glucose for energy.

It's important to note that tumor markers are not specific to cancer and can be elevated in non-cancerous conditions as well. Therefore, they should not be used alone to diagnose cancer but rather as a tool in conjunction with other diagnostic tests and clinical evaluations.

African medicinal plants may stop tumor growth from multi-drug resistant cancers: Research ... African medicinal plants may stop tumor growth from multi-drug resistant cancers: Research. Reprinting this article: Non- ... African medicinal plants may stop tumor growth from multi-drug resistant cancers: Research. Wednesday, June 26, 2013 by: David ... "The active substances present in African medicinal plants may be capable of killing off tumor cells that are resistant to more ...

https://www.naturalnews.com/040947_cancer_treatment_African_plants_medicinal_herbs.html

Tumor, Plant #2. 2005. Charcoal 27 x 35. Click on Image to Enlarge ... Tumor, Plant #1. 2006. Charcoal. 35 x 27. Click Image to Enlarge ...

https://jillianludwig.com/drawings/charcoal-drawings-tumors-plants----/view/82

A childs brain tumor yields a church plant in metro Toronto. Posted by admin , Mar 6, 2012 , Baptist News , 0 , ... Their 8-year-olds battle with a brain tumor sensitized Jason and Kimberley McGibbon to peoples spiritual needs in Hamilton, ... Ontario, Canada, where they now are planting a church as North American Mission Board missionaries. ...

https://baptist.org/a-childs-brain-tumor-yields-a-church-plant-in-metro-toronto/

Research in 1997 shown that TCTP is not a tumor- or tissue-specific protein, but is expressed ubiquitously from plants to ... Translationally controlled tumor protein has a role in tumor reversion and development. TCTP is a regulator of the cancer stem ... "Dark-induced accumulation of mRNA for a homolog of translationally controlled tumor protein (TCTP) in Pharbitis". Plant & Cell ... growth-related mouse tumor protein TCTP. TCTP was originally described as a growth related protein of tumor cells. Its mRNA ...

https://en.wikipedia.org/wiki/Translationally_controlled_tumor_protein

CWRU Awarded Funding to Understand How A Virus-Like Particle from Plants Stimulates Potent Anti-Tumor Response Article Date ... CWRU Awarded Funding to Understand How A Virus-Like Particle from Plants Stimulates Potent Anti-Tumor Response ... With tumor growth, cancer cells release substances known as tumor-associated antigens into the blood stream. These antigens ... to recognize and kill the tumor cells using the tumor-associated antigens. Traveling through the blood stream, the activated ...

https://case.edu/medicine/about/newsroom/our-latest-news/cwru-awarded-funding-understand-how-virus-particle-plants-stimulates-potent-anti-tumor-response

This Plant Gives Your Yard Color Without Any Work. Isnt that what were all after? ... Home / Entertainment / Ed Sheeran Reveals Trauma of Wifes Tumor During Pregnancy and Best Friends Death-I Felt Like I Was ... Sheerans Wife Cherry Seaborn Had a Tumor While Pregnant. JMEnternational/Getty Images. Sheeran and his wife welcomed their ... Ed Sheeran Reveals Trauma of Wifes Tumor During Pregnancy and Best Friends Death-"I Felt Like I Was Drowning". ...

https://bestlifeonline.com/news-ed-sheeran-trauma/

... consecutive to pediatric brain tumors, with no prior visual rehabilitation performed fifteen minutes of home-based audiovisual ... consecutive to pediatric brain tumors, with no prior visual rehabilitation performed 15 min of home-based audiovisual ... virtual-reality visual rehabilitation program for adult patients with hemianopia consecutive to a pediatric brain tumor. We ... Visual field loss is frequent in patient with brain tumors, worsening their daily life, exacerbating the burden of disease and ...

https://www.frontiersin.org/articles/10.3389/fneur.2021.680211/full

Tumor Origin Detection with Tissue-Specific miRNA and DNA methylation Markers. Wei Tang, Shixiang Wan, Quan Zou ... Tumor Origin Detection with Tissue-Specific miRNA and DNA methylation Markers Message Subject (Your Name) has forwarded a page ...

https://www.biorxiv.org/content/10.1101/090746v1.article-metrics

KD fat composition to increase tumour saturated fatty acid levels cooperates with decreased tumour SCD activity to slow tumour ... and CR also impairs tumour SCD activity to cause an imbalance between unsaturated and saturated fatty acids to slow tumour ... By contrast, although KD also impairs tumour SCD activity, KD-driven increases in lipid availability maintain the unsaturated ... These data suggest that diet-induced mismatches between tumour fatty acid desaturation activity and the availability of ...

https://www.nature.com/articles/s41586-021-04049-2?error=cookies_not_supported&code=71a154af-e704-42db-9206-4df283b6aef0

... inhibition of tumor growth and a 3-fold increase in the life span of tumor bearing animals compared to untreated tumor mice. ... Hence, the risk of cancer can be repressed by eating more fruits, vegetables and other plant products1,2,3. Meta-analyses of ... Tumor size was measured using vernier calipers on alternative days for tumor animals and tumor volume was calculated using the ... c). The gross appearance of normal, control tumor and treated tumor animals and their tumor tissues on 16th day of MESF ...

https://www.nature.com/articles/srep06147?error=cookies_not_supported&code=beb5b174-9d9a-43f8-a896-176d7fd1476f

Borderline ovarian tumors are abnormal cells or growths that develop in the ovaries. Although they are not cancerous, they may ... Not all plant-based diets linked to a lower risk of Parkinsons disease ... of borderline ovarian tumors are stage 1 at the point of diagnosis, meaning tumors are confined to the ovaries or fallopian ... Stage 3: Involves the tumor spreading to the abdominal cavity.. *Stage 4: The most advanced stage, in which tumor cells have ...

https://www.medicalnewstoday.com/articles/borderline-ovarian-tumor

Together, these studies identify T cell-mediated tumor regression as the mechanism through which a plant-derived essential oil ... 28 tumors). CWO treated tumors regressed (wk 0=12 tumors vs wk 11=0 tumors). Arrow denotes a malignant conversion in the ... Finally, we sought to determine active compounds in CWO that stimulate tumor regression. As a natural plant derivative, CWOs ... Four pre-malignant tumors of approximately the same size per mouse were pooled (N=3 mice per treatment). The pooled tumors were ...

https://www.biorxiv.org/content/10.1101/386789v1.full

Plant is a pediatric neuro-oncologist with a focus on early phase clinical trials for pediatric brain tumors and immunotherapy. ... Plant is a pediatric neuro-oncologist with a focus on early phase clinical trials for pediatric brain tumors and immunotherapy. ...

https://cbtn.org/research-partners/ashley-plant

Posts about anti-tumor written by Nan Kathryn Fuchs PhD, Christine Horner MD FACS, and David L. Hoffmann BSc Hons MNIMH ... This indigenous plant of Asia and India has been a superstar of the pharmacopoeia of... ... Whether You Want to Prevent or Treat Tumors These Powerful Nutrients Boost Your Fight Against Cancer. Nan Kathryn Fuchs PhD ... The National Cancer Institute defines these terms in the following way A cytotoxic agent is toxic to tumors in laboratory ...

https://healthy.net/tag/anti-tumor/

If you are a caregiver of someone living with a brain tumour, we are here to help! We have various support tools available just ... You can also go to any of the Brain Tumour Support Groups located across Canada. For more information, explore Brain Tumour ... Water plants. Tip to friends and family who want to help: Offer your time. Be very specific with your offering (i.e.) "I am all ... Talking with Your Child / Teen About a Brain Tumour Diagnosis. Helping your child or teen understand a brain tumour diagnosis ...

https://www.braintumour.ca/care-support/caregiver-corner/

The mice were divided into five groups: (1) tumor control; (2) lycopene (5 mg/kg); (3) sorafenib (30 mg/kg); (4) lycopene (2 mg ... The results showed that lycopene reduced the number of metastatic tumors in the lungs, which was further suppressed by the ... The results showed that lycopene reduced the number of metastatic tumors in the lungs, which was further suppressed by the ... the present study demonstrates that lycopene in combination with sorafenib additively inhibits the lung metastasis of tumor, ...

https://www.frontiersin.org/articles/10.3389/fnut.2022.886988/full

Plant extract fights brain tumor February 10, 2015 Silibinin from milk thistle seeds as novel, non-invasive treatment strategy ... After Silibinin treatment, tumor cells resumed normal ACTH production, tumor growth slowed down and symptoms of CD disappeared. ... Using Silibinin, a plant extract from milk thistle seeds, as a HSP90 inhibitor, the researchers discovered a non-invasive ... Cushing´s disease (CD) is a rare hormone condition caused by a tumor in the pituitary gland in the brain. Patients suffering ...

https://www.mpg.de/12126629/silibinin-license-morbus-cushing?print=yes

Oxidative stress is crucial to the biology of tumors. Oxidative stress’ potential predictive significance in colorectal ... Six-well plates containing SW80 cells were planted with 5,105 cells per well. 250 l of Opti-MEM was added to two EP tubes once ... "A novel tumor-homing TRAIL variant eradicates tumor xenografts of refractory colorectal cancer cells in combination with tumor ... correlation between risk score model and tumor infiltrating immune cell function. ; ; . ...

https://www.hindawi.com/journals/omcl/2022/2518340/

Study shows that psychotropic plants can help treat diabetes. April 26, 2019 ... The researchers obtained samples from 703 human melanoma tumors and 353 metastatic ones (tumors that have spread from the ... such as the thickness of the melanoma tumors, how fast they grew and genetic alterations that caused faster tumor growth. ... Home›Health›Battling skin cancer: Vitamin D may be used to boost anti-tumor activity, study finds ...

https://www.lecanadian.com/health/battling-skin-cancer-vitamin-d-may-be-used-to-boost-anti-tumor-activity-study-finds.html

A disturbing photograph of a white-tailed deer covered with large tumors is back to making the rounds on social media. T ... Text above the photo says, "A deer became riddled with tumors from eating plants sprayed with Monsantos Roundup. It seems ... Says a deer became riddled with tumors from eating plants sprayed with Monsantos Roundup. ... Says a deer became "riddled with tumors from eating plants sprayed with Monsantos Roundup." ...

https://www.politifact.com/factchecks/2019/may/17/viral-image/no-deer-covered-tumors-viral-photo-was-not-caused-/

The first sign of trouble for a patient with a growing brain tumor is often a seizure. Such seizures have long been considered ... Researchers develop implantable hydrogels based on plant polysaccharides Far Eastern Federal University (FEFU) scientists have ... Manipulating cancer cell metabolism may help combat DIPGs and other brain tumors Every year, 150 to 300 children in the United ... Progress against DIPG, a fatal childhood brain tumor, is usually a game of inches. Studies that hint at even small gains are ...

https://www.news-medical.net/?tag=/Glioma&page=7

Tumor microenvironment remodeling in oral cancer: Application of plant derived-natural products and nanomaterials.. Budi, ... Therefore, several studies have been conducted to modulate the TME in various types of tumors in favor of cancer suppression. ... Nowadays, studies have confirmed the remarkable effects of the tumor microenvironment (TME) on the development, invasion, and ... and classical chemotherapy drugs have been used to control the growth of oral tumors. ...

https://pesquisa.bvsalud.org/odontologia/resource/pt/mdl-37331557

Smith SL, Plant D, Eyre S, Barton A. The potential use of expression profiling: implications for predicting treatment response ... Cohen, S., Wells, A.F., Curtis, J.R. et al. A Molecular Signature Response Classifier to Predict Inadequate Response to Tumor ... Outcomes of tumor necrosis factor inhibitor cycling versus switching to a disease-modifying anti-rheumatic drug with a new ... Tumor necrosis factor-α inhibitor (TNFi) therapies are the most prescribed targeted therapy in RA, although only approximately ...

https://link.springer.com/article/10.1007/s40744-021-00330-y

eCg Plant height (e), panicle and internode lengths (f), and diameter (g) in the wild type and the mutant. In plants, ... eCg Plant height (e), panicle and internode lengths (f), and diameter (g) in the wild type and the mutant. by fabretp ...

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... in part by NIBIB have recently shown that magnetic bacteria are a promising vehicle for more efficiently delivering tumor- ... Two years worth of net global carbon emissions could be saved by upgrading iron and steel plants. ... meant to direct the cells or beads into the tumor. Upon examination of the tumors, the researchers found minimal penetration of ... Home magnetic bacteria Swarms of magnetic bacteria could be used to deliver drugs to tumors ...

https://innovationtoronto.com/2016/09/swarms-of-magnetic-bacteria-could-be-used-to-deliver-drugs-to-tumors/

Mast cell tumors are an increasingly common health issue in dogs. But there are natural options that are safe and effective. ... I like to use a tincture of the entire plant for mast cell tumors. The flowering tops and roots help with excess histamine ... Most grade III tumors are defined as stage III. This means there are multiple tumors … or one large tumor with lymph node ... Stage II: One tumor in the skin with lymph node involvement.. Stage III: Multiple large, deep skin tumors, with or without ...

https://www.dogsnaturallymagazine.com/natural-approach-mast-cell-tumors-in-dogs/

A plant breeder succeeds in growing a huge maize plant thanks to a known mutation and a few environmental tricks. ... Tumors mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells. ... Extra Centrosomes Can Drive Tumor Formation in Mice. Mice engineered to overproduce the organelles involved in cell division ... Now we need to quantify more protein biomarkers, assess the tumor mutational landscape, and examine immune cell signatures, too ...

https://www.the-scientist.com/magazine/issue/targeting-tumors-31-4

Novel Concepts Medical has recently achieved success in its research on cancer treatment using a plant-based formula. The ... Novel Concepts Medical plant based formula has reversed the growth of cancer tumors - case studies report. ... Novel Concepts Medical plant based formula has reversed the growth of cancer tumors - case studies report ... Novel Concepts Medical plant based formula has reversed the growth of cancer tumors - case studies report ...

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the resulting effect is often seen as a double-edged sword, with great controversy over the tumor-promoting and tumor-suppressing effects [ 6 , 10 ], the specific effect of ROS levels on tumor cells themselves, [ 11 ] sensitivity and lack of oxygen, and the tumor microenvironment of regulatory factors. (hindawi.com)
Tumor microenvironment remodeling in oral cancer: Application of plant derived-natural products and nanomaterials. (bvsalud.org)
Nowadays, studies have confirmed the remarkable effects of the tumor microenvironment (TME) on the development, invasion, and therapeutic resistance of tumors like oral cancers. (bvsalud.org)
Through similar mechanisms, amino acid depletion in culture and cytokine activity in the tumor microenvironment prompt cancer cells to metastasize. (the-scientist.com)
Modern anti-cancer strategies should be designed to selectively target CSCs and modulate the hypoxic and acidic tumor microenvironment, and, to this end, natural bioactive components seem to play a role. (uneatlantico.es)
This review aims to discuss the effects elicited by plant-derived bioactive nutrients in the regulation of CSC self-renewal, cancer metabolism and tumor microenvironment. (uneatlantico.es)
Zhao, Y. Chemotherapy and tumor microenvironment of pancreatic cancer. (eurekaselect.com)

Scientists of Far Eastern Federal University get started studying the formation and survival mechanisms of the brain malignant tumors cells, i.e. glioma, to reveal new ways for diagnosis and therapy for this fatal disease. (news-medical.net)
Levels of ether lipids - a class of lipids that are harder to break down - are particularly elevated in highly malignant tumors, although the nature of that correlation has been unclear for decades. (scitechdaily.com)
Most of the malignant tumors produce markers that can be serologically assessed. (medscape.com)

More importantly, we show that MESF treatment leads to significant inhibition of tumor growth and a 3-fold increase in the life span of tumor bearing animals compared to untreated tumor mice. (nature.com)
In a separate experiment with mice, the team found that increasing VDR expression on melanoma cells reduced the activity of the Wnt/Beta-catenin pathway and slowed down tumor growth. (lecanadian.com)
In an initial experiment, mice that had been given human colorectal tumors were injected with either live MC-1 cells, dead MC-1 cells, or as a control group, non-magnetic beads (roughly the same size as the bacteria). (innovationtoronto.com)
The injection was made into the tissue directly adjacent to the tumors after which the mice were exposed to a computer-programmed magnetic field, meant to direct the cells or beads into the tumor. (innovationtoronto.com)
The cells were then injected into another set of mice with colorectal tumors and exposed to the magnet. (innovationtoronto.com)
After examining the tumors of those mice, the researchers estimated that on average, 55% of the injected bacterial cells with attached vesicles made it into the tumor. (innovationtoronto.com)
The reduction in tumor volume as well as pro-apoptotic and anti-proliferative effects in HT-29 nude mice xenograft are comparable to those produced by 5-FU. (spandidos-publications.com)
Results: DMC significantly reduced tumor weights and volumes of HeLa cell xenografts in mice, indicating the suppression of growth of xenograft tumors. (iiarjournals.org)
Among the mice that had the AGPS enzyme inactivated, the tumors were nonexistent," said Nomura. (scitechdaily.com)
The mice that did not have this enzyme disabled rapidly developed tumors. (scitechdaily.com)
Thus, in tumor-bearing mice, 60% tumor reduction was observed, while in metastatic mice, the number of nodules decreased by 25% compared to the control group. (researchgate.net)
Moreover, I. obliquus extract-treated mice demonstrated the increase in tumor agglomeration and inhibition of vascularization. (researchgate.net)
Furthermore, I. obliquus prevented temperature drop in mice after tumor implantation. (researchgate.net)

Increased serine synthesis provides an advantage for tumors arising in tissues where serine levels are limiting. (nature.com)
Borderline ovarian tumors that have advanced beyond stage 1 can grow in size and spread to nearby tissues and lymph nodes , as well as distant areas of the body. (medicalnewstoday.com)
One of the biggest challenges in cancer therapy is being able to sufficiently deliver chemotherapy drugs to tumors without exposing healthy tissues to their toxic effects. (innovationtoronto.com)
Yet while nanocarriers do a good job protecting healthy tissues, the amount of drug successfully delivered to tumors remains low. (innovationtoronto.com)
The tumor size and the number of proliferating cells were reduced in the tumor tissues obtained from the formononetin-treated group. (spandidos-publications.com)
Tissue culture commonly refers to the culture of animal cells and tissues, with the more specific term plant tissue culture being used for plants. (wikipedia.org)
Gottlieb Haberlandt first pointed out the possibilities of the culture of isolated tissues, plant tissue culture . (wikipedia.org)

Therefore, several studies have been conducted to modulate the TME in various types of tumors in favor of cancer suppression . (bvsalud.org)
Besides, many studies have proved that ethanol extract from radix of Actinidia chinensis (EERAC) has an obviously curative effect on several types of tumors including hepatocellular carcinoma and lung cancer, [ 15 - 17 ]. (jcancer.org)
The outlook varies greatly for different types of tumors. (medlineplus.gov)

The significant inhibition of tumor growth by EERAC was also observed. (jcancer.org)

NaturalNews) Traditional African medicinal plants may contain naturally occurring compounds that effectively kill drug-resistant cancers, according to research conducted by Victor Keute of the University of Dschang in Cameroon and Thomas Efferth of Johannes Gutenberg University Mainz in Germany. (naturalnews.com)
Data by Steinmetz and Fiering [Steinmetz, Fiering, Nature Nanotechnology, 2016] show that the proposed nanoparticle cancer immunotherapy generates a highly potent anti-tumor immunity response even in cancers such as melanomas, which are resistant to attack by the immune system. (case.edu)
Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability. (nature.com)
Preclinical and clinical studies have established plant derived dietary substances as suitable candidates for treating various types of cancers due to their broad chemical diversity. (nature.com)
These findings suggest that formononetin inhibits angiogenesis and tumor cell invasion, and thus support its use in the treatment of advanced and metastatic colon cancers. (spandidos-publications.com)
Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers. (broadinstitute.org)
Here, in a prospective cohort of 42 patients with molecularly defined gastrointestinal cancers and acquired resistance to targeted therapy, direct comparison of postprogression cfDNA versus tumor biopsy revealed that cfDNA more frequently identified clinically relevant resistance alterations and multiple resistance mechanisms, detecting resistance alterations not found in the matched tumor biopsy in 78% of cases. (broadinstitute.org)

In addition to melanoma, the proposed therapy exhibits clear treatment efficacy and similar anti-tumor immunity performance in metastatic ovarian and metastatic breast tumor models. (case.edu)
The results showed that lycopene reduced the number of metastatic tumors in the lungs, which was further suppressed by the combined treatment with sorafenib. (frontiersin.org)
The researchers obtained samples from 703 human melanoma tumors and 353 metastatic ones (tumors that have spread from the original site) to study the expression of the gene that has the instructions for making VDR. (lecanadian.com)

Expression levels of TCTP were down-regulated at the mRNA and protein levels during tumor suppression and by the activation of p53 and Siah-1 very well known anti-tumor genes. (wikipedia.org)
In vivo , CWO induced transcriptional changes in immune-related genes, resulting in cytotoxic T cell-dependent tumor regression. (biorxiv.org)
Gliomas with mutations in what are called the isocitrate dehydrogenase (IDH) genes are the most common brain tumors diagnosed in younger adults aged 18 to 45 years. (news-medical.net)
8/1/2016 - Genetically-modified organisms (GMOs) could soon go the way of the dodo bird, thanks to an emerging new crop management technology that capitalizes on natural plant and soil microbes, rather than harsh chemicals and foreign genes, to combat pests and boost crop yields. (naturalnews.com)
and the tumor suppressor genes WT1 and MASH2 are imprinted, depending on their maternal or paternal origin. (medscape.com)

Two patients, one with homonymous hemianopia and the other with bitemporal hemianopia, consecutive to pediatric brain tumors, with no prior visual rehabilitation performed 15 min of home-based audiovisual stimulation every 2 days for 6 weeks (case 2) and 7 weeks (case 1) between February and August 2020. (frontiersin.org)
Dr. Plant is a pediatric neuro-oncologist with a focus on early phase clinical trials for pediatric brain tumors and immunotherapy. (cbtn.org)

He may perform CT scans, and, if he finds a tumor in your dog's nasal cavity, he'll certainly biopsy it. (vetinfo.com)
A biopsy can help your vet determine if the tumor in your dog's nose is cancerous or benign (non-cancerous). (vetinfo.com)
Depending on the location of the tumor, the biopsy may be a simple procedure or a serious operation. (medlineplus.gov)
An endoscopic biopsy that yields hair or plant material is diagnostic. (msdmanuals.com)

The third, oncogene-mediated resistance, occurs when the epidermal growth factor receptor (EGFR) signals cancerous tumors to accelerate their growth, overwhelming the capacity of drugs to kill them. (naturalnews.com)
Are borderline ovarian tumors cancerous? (medicalnewstoday.com)
Tumors can be cancerous (malignant) or noncancerous (benign). (medlineplus.gov)
It is done to determine if the tumor is noncancerous (benign) or cancerous (malignant). (medlineplus.gov)
If the tumor is cancerous, the outcome depends on the type and stage of the tumor at diagnosis. (medlineplus.gov)

TEL AVIV, Israel - The startup company Novel Concepts Medical is delighted to announce breakthrough results reducing the size of cancer tumors in its research regarding our plant-based cancer treatment. (novelconceptsmedical.com)

Colorectal cancer (CRC) is a common malignant tumor of the gastrointestinal tract [ 1 ]. (hindawi.com)
Colorectal cancer (CRC) is a common public health problem, being one of the most common gastrointestinal tumors in the world [ 1 , 2 ]. (jcancer.org)

Xenograft tumor assay was applied to detect the influence of EERAC on tumor growth. (jcancer.org)

Borderline ovarian tumors (BOTs) are abnormal cells or growths that develop in the tissue encapsulating an ovary. (medicalnewstoday.com)
According to the National Cancer Institute (NCI), around 75% of borderline ovarian tumors are stage 1 at the point of diagnosis, meaning tumors are confined to the ovaries or fallopian tubes. (medicalnewstoday.com)
A doctor will need to properly diagnose a BOT since treatment for his type of tumor differs from treatment for ovarian tumors that are definitively malignant. (medicalnewstoday.com)
Another study from 2021 notes that BOTs account for 10-15% of ovarian epithelial tumors. (medicalnewstoday.com)
Can borderline ovarian tumors spread? (medicalnewstoday.com)
Fox Chase Cancer Center scientists have identified how an enzyme called COX-2 may promote the development of ovarian tumors, adding further insight into the mechanism of COX-2 inhibitors and the prevention of this highly lethal disease. (news-medical.net)

A practice-changing study, NRG Oncology clinical trial NRG-RTOG 9802, has demonstrated, for the first time, a survival benefit of adjuvant chemotherapy following radiotherapy over radiotherapy alone in certain subgroups of patients with high-risk, low-grade glioma (WHO classification: LGG, grade II), a type of brain tumor that originates from glial cells. (news-medical.net)
For many years, different modalities such as surgery , radiation therapy , and classical chemotherapy drugs have been used to control the growth of oral tumors . (bvsalud.org)
While chemotherapy is not the most effective treatment for this type of cancer, there is a chance that radiation therapy could reduce the size of the tumor. (vetinfo.com)
Effective chemotherapy agents need to be delivered efficiently, distributed mostly in the tumor tissue, and highly internalized by tumor cells to eventually inhibit proliferation or promote death of the tumor cells. (eurekaselect.com)

We tested an essential-oil derivative, camphor white oil (CWO), for anti-tumor activity in a mouse model of keratinocyte-derived skin cancer. (biorxiv.org)
Anti-tumor activity occurs if this. (healthy.net)

TCTP is a regulator of the cancer stem cell compartment, the tumor reversion, tumor progression and certain forms of inflammatory diseases. (wikipedia.org)
Angiogenesis is essential in the process of carcinogenesis to facilitate tumor progression and metastasis. (spandidos-publications.com)
However, the effectiveness of cfDNA versus standard single-lesion tumor biopsies has not been directly compared in larger-scale prospective cohorts of patients following progression on targeted therapy. (broadinstitute.org)

Find connections and lean on others who have experienced the diagnosis of a brain tumour. (braintumour.ca)
If you suspect a mast cell tumor, take your dog to the vet for diagnosis so that you can decide on the best treatment option. (dogsnaturallymagazine.com)
however, the treatment of patients with cervical cancer depends on the cancer stage and tumor location according to diagnosis and characteristics of the patients ( 7 , 8 ). (iiarjournals.org)

New monoclonal antibodies kill both cancer-promoting immunosuppressive cells and tumor cells in culture. (the-scientist.com)
In the present study, we aimed to further examine the potential of formononetin in controlling angiogenesis and tumor cell invasiveness in human colon cancer cells and tumor xenografts. (spandidos-publications.com)
In recent years, we focused on investigating the anti-carcinogenic properties of total Astragalus saponins (AST) in human colon cancer cells and tumor xenografts. (spandidos-publications.com)

In the present study, we aimed to investigate the effects of continuous intake of aqueous extract from I. obliquus on tumor suppression. (researchgate.net)

Overall, the present study demonstrates that lycopene in combination with sorafenib additively inhibits the lung metastasis of tumor, indicating lycopene has potential as an adjuvant for sorafenib in cancer treatment. (frontiersin.org)
The oxidative stress factor plays a significant role in numerous stages of tumor advancement, including the transformation of normal cells into tumor cells, proliferation, tumor angiogenesis, and metastasis [ 5 - 8 ]. (hindawi.com)
ROS can also promote the metastasis and proliferation of tumor cells [ 15 ]. (hindawi.com)
In particular, plant-derived bioactive nutrients have been seen to positively affect normal cell growth, proliferation and differentiation and also to revert cancer related epigenetic dysfunctions, reducing tumorigenesis, preventing metastasis and/or increasing chemo and radiotherapy efficacy. (uneatlantico.es)

The bad prognosis induced tumor metastases and invasion leads to the low five-year survival rate of CRC patients [ 3 ]. (jcancer.org)

Researchers have long known that a person's immune system has the potential to recognize and destroy tumor cells. (case.edu)
The antigen-presenting cells capture the tumor-associated antigens and transport them to another class of specialized immune cells known as cytotoxic T lymphocytes. (case.edu)
But as a tumor progresses, it may respond to the body's natural immunity system by activating immune-suppressive mechanisms, essentially turning off the body's own cancer-defense mechanisms. (case.edu)
Conversely, the Steinmetz immunotherapy strategy can "flip the switch" by turning off the immune-suppressive environment and turning on the cancer immunity cycle to elicit a potent immune response against the tumor. (case.edu)
Besides, administration of concentrated extracts of Morinda citrifolia in tumor containing animals increased the immune response of the animals with a concomitant reduction in tumor burden 7 . (nature.com)
SUMMARY BLURB Essential oil derived from the camphor tree acts by stimulating immune cell-dependent regression of skin tumors in a mouse model of cutaneous squamous cell carcinoma. (biorxiv.org)
The researchers found that human tumors with low VDR gene expression grew more rapidly and displayed reduced expression of proteins involved in promoting immune-mediated anti-cancer activity. (lecanadian.com)
We know when the Wnt/Beta-catenin pathway is active in melanoma , it can dampen down the immune response, causing fewer immune cells to reach the inside of the tumor, where they could potentially fight the cancer better," explained Newton-Bishop. (lecanadian.com)
A Ludwig Cancer Research study has dissected how radiotherapy alters the behavior of immune cells known as macrophages found in glioblastoma (GBM) tumors and shown how these cells might be reprogrammed with an existing drug to suppress the invariable recurrence of the aggressive brain cancer. (news-medical.net)
Now we need to quantify more protein biomarkers, assess the tumor mutational landscape, and examine immune cell signatures, too. (the-scientist.com)
Problems with the body's immune system can lead to tumors. (medlineplus.gov)

So far, they have tested a total of more than 100 plants and spices in search of cytotoxic (cancer-killing) effects. (naturalnews.com)
The antigen-presenting cells "train" the cytotoxic T lymphocytes (killer T cells) to recognize and kill the tumor cells using the tumor-associated antigens. (case.edu)
The National Cancer Institute defines these terms in the following way A cytotoxic agent is toxic to tumors in laboratory cultures. (healthy.net)

Translationally controlled tumor protein was first discovered in 1989 as a cDNA sequence obtained from a human mammary carcinoma cDNA library with proves derived from the translationally controlled, growth-related mouse tumor protein TCTP. (wikipedia.org)
TCTP knockdown in primary mammary tumor cells, results in increased p53 expression and a decreased number of stem-like cancer cells. (wikipedia.org)
The study - published Wednesday in Food and Chemical Toxicology - found that rats who were exposed to Roundup, a weed killing herbicide, and rats who were fed Roundup-resistant corn developed mammary tumors, kidney and liver damage and died earlier than those in the control group. (foodsafetynews.com)
Mammary tumors began to appear in females after 4 months, he said, and "after one year there was a high increase of a number of (kinds of) tumors. (foodsafetynews.com)
The groups with the GMO surprisingly also had hormonal disruptions and there were also mammary tumors. (foodsafetynews.com)
After a detailed analysis of the chemical composition of the animals' diets, researchers found that two compounds in plants that protect animals against mammary tumors and toxicity of the kidney and liver were reduced to 51 percent with the consumption of the GM corn. (foodsafetynews.com)

Lien, E. C. & Vander Heiden, M. G. A framework for examining how diet impacts tumour metabolism. (nature.com)
Other studies have investigated specific lipid signaling pathways, but what makes AGPS stand out as a treatment target is that the enzyme seems to simultaneously regulate multiple aspects of lipid metabolism important for tumor growth and malignancy. (scitechdaily.com)
This study sheds considerable light on the important role that AGPS plays in ether lipid metabolism in cancer cells, and it suggests that inhibitors of this enzyme could impair tumor formation," said Benjamin Cravatt, professor and chair of chemical physiology at The Scripps Research Institute, who is not part of the UC Berkeley study. (scitechdaily.com)

CNTs can not only increase drug delivery accuracy and efficiency but also promote drug uptake, decrease drug efflux, improve tumor hypoxia conditions, and induce autophagy and apoptosis in tumor cells, which make the tumor more sensitive to antitumor agents. (eurekaselect.com)

Upon examination of the tumors, the researchers found minimal penetration of the dead bacterial cells and the beads into the tumor, whereas the live bacterial cells were found deep within the tumor and especially in regions with low oxygen content. (innovationtoronto.com)

The active substances present in African medicinal plants may be capable of killing off tumor cells that are resistant to more than one drug," Efferth said. (naturalnews.com)
Yet the researchers have already discovered substances from the African plants that are effective against all of these strategies. (naturalnews.com)
We are now looking for substances that can both break down tumor resistance and not produce side effects," Efferth said. (naturalnews.com)
With tumor growth, cancer cells release substances known as tumor-associated antigens into the blood stream. (case.edu)

Several types of Traditional Chinese Medicines have been proved to be a potent anti-tumor agent [ 8 ]. (jcancer.org)

When the content of ROS is insufficient to break the balance between oxidative and antioxidant systems in the tumor growth environment, it can participate in the regulation of epithelial-mesenchymal transition (EMT), tumor angiogenesis, and other processes by activating PI3K/Akt and NF- κ B signaling pathways [ 12 - 14 ]. (hindawi.com)
The vascular endothelial growth factor (VEGF) is a well characterized angiogenic factor known to stimulate angiogenesis within a tumor ( 1 ). (spandidos-publications.com)

Every year, 150 to 300 children in the United States are diagnosed with diffuse intrinsic pontine gliomas (DIPGs), aggressive and lethal tumors that grow deep inside the brain, for which there are no cures. (news-medical.net)
A team led by Massimo Squatrito, Head of the Seve Ballesteros Foundation Brain Tumour Group at the Spanish National Cancer Research Centre, have made important findings of how some gliomas can acquire chemoresistance. (news-medical.net)
A shift towards left sided tumor location for all adult gliomas was noted in this study following the introduction of mobile phones. (greenmedinfo.com)

Down-regulation of TCTP can induce tumor reversion, and in combination with some drugs that decrease the level of TCTP and will lead to kill tumor cells. (wikipedia.org)

In their research, Efferth and Kuete are testing the African plants against a cancer cell line that uses three separate drug-resistance strategies. (naturalnews.com)
The second, tumor-suppressor-gene-mediated resistance, results from a mutation to protein p53 that makes cancer cells enormously aggressive and resistant. (naturalnews.com)
Moreover, virtually all cancer types are characterized by the presence of cancer stem cell (CSC) subpopulations, residing in specific hypoxic and acidic microenvironments, or niches, and these cells are currently considered responsible for tumor resistance to therapy and tumor relapse. (uneatlantico.es)
During cancer therapy, tumor heterogeneity can drive the evolution of multiple tumor subclones harboring unique resistance mechanisms in an individual patient. (broadinstitute.org)

These data suggest that diet-induced mismatches between tumour fatty acid desaturation activity and the availability of specific fatty acid species determine whether low glycaemic diets impair tumour growth. (nature.com)
Fig. 4: Low glycaemic diets impair tumour SCD, which interacts with changes in lipid availability to affect tumour growth. (nature.com)

Tumors' mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells. (the-scientist.com)

Teratomas (from Greek teras, "monster," and - oma, a suffix denoting a tumor or neoplasm) and other germ cell tumors (GCTs) are relatively common solid neoplasms in children. (medscape.com)

After Silibinin treatment, tumor cells resumed normal ACTH production, tumor growth slowed down and symptoms of CD disappeared. (mpg.de)
Other symptoms of nasal tumors include sneezing excessively, watering eyes, halitosis and loss of appetite. (vetinfo.com)
There are a number of other conditions that may cause some of the symptoms of dog sinus tumors, like sneezing, discharge and watering eyes. (vetinfo.com)
If your dog's condition is too far advanced to benefit from treatment, or if treatment doesn't help reduce or eliminate nasal tumors, your vet will prescribe anti-inflammatories and other pain medication to help ease your dog's symptoms as the disease runs its course. (vetinfo.com)
Symptoms depend on the type and location of the tumor. (medlineplus.gov)
Some tumors may not cause any symptoms. (medlineplus.gov)
Sometimes benign tumors may be removed for cosmetic reasons or to improve symptoms. (medlineplus.gov)

Daily topical treatment with CWO induced dramatic regression of pre-malignant skin tumors and a two-fold reduction in cutaneous squamous cell carcinomas. (biorxiv.org)
In a flavoring manufacturing plant in The Netherlands, control measures taken to enclose the process, led to a reduction in air concentrations from 7.6 to 0.7 mg/m3 (geometric mean). (who.int)

With two commercially available inhibitors, the cell cycle of the cancer cells in the childhood tumour neuroblastoma can be disrupted at a key point causing tumour cell death. (uni-wuerzburg.de)

The group treated with Roundup showed the greatest incidence of tumors. (foodsafetynews.com)
The second study investigated the incidence of brain tumor deaths among petrochemical workers (SIC-2911) who produced ethylene-oxide (75218), vinyl-chloride (75014), acetates, and ethylene-amines. (cdc.gov)

Upregulation of stearoyl-CoA desaturase (SCD), which synthesises monounsaturated fatty acids, is required for cancer cells to proliferate in a lipid-depleted environment, and CR also impairs tumour SCD activity to cause an imbalance between unsaturated and saturated fatty acids to slow tumour growth. (nature.com)
By contrast, although KD also impairs tumour SCD activity, KD-driven increases in lipid availability maintain the unsaturated to saturated fatty acid ratios in tumours, and changing the KD fat composition to increase tumour saturated fatty acid levels cooperates with decreased tumour SCD activity to slow tumour growth. (nature.com)

Colorectal cancer (CRC) is one of the most common tumors, and its five-year survival is still very low despite of the advance of treatment strategies. (jcancer.org)

2/3/2016 - Scientists are beginning to uncover the mechanisms by which plants -- which depend upon sunlight to provide them with energy -- protect themselves from the damaging effects of the sun's ultraviolet rays. (naturalnews.com)

Key findings: The extract of I. obliquus caused significant tumor suppressive effects in both models. (researchgate.net)
The findings may be mistaken for tumors. (msdmanuals.com)

Elevated, although not statistically significant, increased mortality was observed for lymphatic and hematopoietic neoplasms at one of the two plants [stan- dardized mortality ratio (SMR) = 155], in particular lymphosarcoma and reticulosar- coma (SMR = 181) and leukemia (SMR = 203). (cdc.gov)

Central nervous system tumors are the second most common malignancies in childhood ( 1 ). (frontiersin.org)
Progress against DIPG, a fatal childhood brain tumor, is usually a game of inches. (news-medical.net)

That means that when analyzing the defensive chemicals produced by plants, scientists need to work hard to distinguish between those that are medicinal and those that are poisonous or harmful. (naturalnews.com)
Efferth and Kuete have been collaborating together for four years, investigating traditional African medicinal plants including the Ethiopian pepper, giant globe thistle, speargrass and wild pepper. (naturalnews.com)
Formononetin is a novel herbal isoflavonoid isolated from Astragalus membranaceus, a medicinal plant that possesses antitumorigenic properties. (spandidos-publications.com)
8/10/2015 - Plants have been used for thousands of years for medicinal purposes. (naturalnews.com)
You can cut the middle man out and grow medicinal plants in your very own garden. (naturalnews.com)

Last year, the couple had a second daughter and revealed, "Within the space of a month, my pregnant wife got told she had a tumour, with no route to treatment until after the birth. (bestlifeonline.com)
Brain tumor and its treatment can affect the visual system at different levels, from the optic nerves (through compression or infiltration), to subcortical structures like the superior colliculus (SC) and lateral geniculate nuclei (LGN) to optic tracts, optic radiations, and visual cortices ( 1 - 4 ). (frontiersin.org)
Using Silibinin, a plant extract from milk thistle seeds, as a HSP90 inhibitor, the researchers discovered a non-invasive treatment strategy for Cushing´s disease. (mpg.de)
Novel Concepts Medical has recently achieved success in its research on cancer treatment using a plant-based formula. (novelconceptsmedical.com)

An excess of lung cancer was seen in some workers at a polyurethane foam manufacturing plant. (cdc.gov)

Hu W, Wu C, Yuan C, Chen M, Jin C, Zheng C. Ethanol Extracted from Radix of Actinidia Chinensis Inhibits Human Colon Tumor Through Inhibiting Notch-signaling Pathway. (jcancer.org)

Cancer Research UK states that because these tumors are slow-growing and noninvasive, doctors deem them noncancerous. (medicalnewstoday.com)

When they get inside the tumor, we switch off the magnetic field and the bacteria automatically rely on the oxygen sensors to seek out the hypoxic areas," says Martel. (innovationtoronto.com)

Their 8-year-old's battle with a brain tumor sensitized Jason and Kimberley McGibbon to people's spiritual needs in Hamilton, Ontario, Canada, where they now are planting a church as North American Mission Board missionaries. (baptist.org)
Visual field loss is frequent in patients with brain tumors, worsening their daily life and exacerbating the burden of disease, and no supportive care strategies exist. (frontiersin.org)
This is the first report of a home-based virtual-reality visual rehabilitation program for adult patients with hemianopia consecutive to a pediatric brain tumor. (frontiersin.org)
Children with brain tumors can present visual impairments like decreased visual acuity and contrast sensitivity (CS), loss of color vision, and visual field loss such as hemianopias ( 1 - 5 ). (frontiersin.org)
Here, we report, for the first time, the feasibility and potential effectiveness of a visual rehabilitation procedure consecutive to a pediatric brain tumor in two young adult patients with hemianopia. (frontiersin.org)
Find all the ways that caregivers of those living with a brain tumour can find support. (braintumour.ca)
But being a caregiver to someone affected by a brain tumour is so much harder. (braintumour.ca)
Caregivers have questions, fears and feelings of helplessness when someone they care about is diagnosed with a brain tumour. (braintumour.ca)
On this page, you will find multiple ways that you as a caregiver can get support to better assist the person affected by a brain tumour. (braintumour.ca)
This new resource, developed by caregivers and health care professionals is designed to assist the person caring for someone affected by a brain tumour. (braintumour.ca)
We also hope that the personal stories and practical suggestions it contains will help you take care of the person with a brain tumour that you are caring for. (braintumour.ca)
In order to meet the diverse needs of our caregiver community, Brain Tumour Foundation of Canada is pleased to now offer a private facebook support group exclusively for caregivers. (braintumour.ca)
In these online groups you will gain access to an active group of Canadian brain tumour patients, survivors, parents and other caregivers who will be asking questions, answering your questions and sharing stories of hope and support. (braintumour.ca)
If you are the caregiver of a child with a brain tumour in Quebec, British Columbia, Alberta or Southwestern Ontario, please also reference Pediatric and Family Support . (braintumour.ca)
You have a brain tumour"… five words that can bring an overwhelming sense of anxiety, fear and bewilderment. (braintumour.ca)
Certainly, this is the case for the individual with the brain tumour, but also for their loved ones. (braintumour.ca)
As a caregiver to someone living with a brain tumour, your physical, emotional and psychological well-being is as important as that of your patient. (braintumour.ca)
Cushing´s disease (CD) is a rare hormone condition caused by a tumor in the pituitary gland in the brain. (mpg.de)
Benign tumors near or in the brain may be removed because of their location or harmful effect on the surrounding normal brain tissue. (medlineplus.gov)
But a benign tumor can sometimes cause severe problems, such as in or near the brain. (medlineplus.gov)
Twenty two brain tumor deaths occurred where 10.7 were expected among the petrochemical workers. (cdc.gov)
Emphasizing the conclusion's first sentence, Swedish researcher Maria Feychting said: "The use of mobile phones for over ten years shows no increased risk of brain tumors. (cdc.gov)

Normal migration of these germ cells may cause gonadal tumors, whereas abnormal migration produces extragonadal tumors. (medscape.com)

In general, tumors occur when cells divide and grow excessively in the body. (medlineplus.gov)

Research in 1997 shown that TCTP is not a tumor- or tissue-specific protein, but is expressed ubiquitously from plants to mammals. (wikipedia.org)

If the tumor is benign, the outlook is generally very good. (medlineplus.gov)

Tumors of the colon can cause weight loss, diarrhea, constipation, iron deficiency anemia, and blood in the stool. (medlineplus.gov)

In the course of their research they found tremendously high amounts of HSP90 in the tumor tissue of patients. (mpg.de)
When a tumor is found, a piece of the tissue is removed and examined under a microscope. (medlineplus.gov)

Together, these studies identify T cell-mediated tumor regression as the mechanism through which a plant-derived essential oil diminishes established tumor burden. (biorxiv.org)

The problem is that many plant compounds also evolved to deter animal predators, including large mammals such as ourselves. (naturalnews.com)
CWO primarily consist of a mixture of structurally related terpenes, a class of chemical compounds composed of isoprene units with distinct aromatic qualities that plants generate for defensive purposes. (biorxiv.org)
In 2013, the Max Planck scientists together with the technology transfer organization Max Planck Innovation filed a patent, which has been granted in the US and is pending in the EU, covering chemical and natural compounds, including Silibinin, to treat pituitary tumors as further medical use. (mpg.de)

Anatomy3

Organisms5

Chemicals and Drugs4

Phenomena and Processes3

Molecular markers and cell cycle inhibitors show the importance of cell cycle progression in nematode-induced galls and syncytia. (1/273)

Ti plasmids from Agrobacterium characterize rootstock clones that initiated a spread of crown gall disease in Mediterranean countries. (2/273)

Cell-division factors from Vinca rosca L. crown gall tumor tissue. (3/273)

An inherited "neoplasm" in fungus. (4/273)

Suppression of the neoplastic state with the acquisition of specialized functions in cells, tissues, and organs of crown gall teratomas of tobacco. (5/273)

High relatedness and inbreeding at the origin of eusociality in gall-inducing thrips. (6/273)

Bruchins: insect-derived plant regulators that stimulate neoplasm formation. (7/273)

Plant Tumors

Agrobacterium tumefaciens

Rhizobium

Plants, Genetically Modified

Plant Leaves

Plant Proteins

Plant Roots

Genes, Plant

Plant Extracts

Plant Shoots

Plants, Medicinal

DNA, Plant

Plant Development

Plants, Toxic

Tumor Markers, Biological

Molecular markers and cell cycle inhibitors show the importance of cell cycle progression in nematode-induced galls and syncytia. (1/273)

Ti plasmids from Agrobacterium characterize rootstock clones that initiated a spread of crown gall disease in Mediterranean countries. (2/273)

Cell-division factors from Vinca rosca L. crown gall tumor tissue. (3/273)

An inherited "neoplasm" in fungus. (4/273)

Suppression of the neoplastic state with the acquisition of specialized functions in cells, tissues, and organs of crown gall teratomas of tobacco. (5/273)

High relatedness and inbreeding at the origin of eusociality in gall-inducing thrips. (6/273)

Bruchins: insect-derived plant regulators that stimulate neoplasm formation. (7/273)

African medicinal plants may stop tumor growth from multi-drug resistant cancers: Research - NaturalNews.com

Jillian Dickson : Drawings : Charcoal Drawings: "TUMORS, PLANTS"

A child's brain tumor yields a church plant in metro Toronto - Baptist.org Blog | Baptist Articles | Baptist News | Theology |...

Translationally controlled tumor protein - Wikipedia

CWRU Awarded Funding to Understand How A Virus-Like Particle from Plants Stimulates Potent Anti-Tumor Response | School of...

Ed Sheeran Reveals Wife Had a Tumor and His Best Friend Died

Frontiers | Case Report: Visual Rehabilitation in Hemianopia Patients. Home-Based Visual Rehabilitation in Patients With...

Tumor Origin Detection with Tissue-Specific miRNA and DNA methylation Markers | bioRxiv

Low glycaemic diets alter lipid metabolism to influence tumour growth | Nature

Sapodilla Plum (Achras sapota) Induces Apoptosis in Cancer Cell Lines and Inhibits Tumor Progression in Mice | Scientific...

Borderline ovarian tumor: Definition and outlook

Camphor white oil induces tumor regression through cytotoxic T cell-dependent mechanisms | bioRxiv

Ashley Plant MD | Children's Brain Tumor Network

anti-tumor - Healthy.net

Caregiver Corner

Frontiers | Lycopene in Combination With Sorafenib Additively Inhibits Tumor Metastasis in Mice Xenografted With Lewis Lung...

IBI licenses Silibinin for the use in Cushing´s Disease | Max-Planck-Gesellschaft

Prognostic Assessment of Oxidative Stress-Related Genes in Colorectal Cancer and New Insights into Tumor Immunity

Battling skin cancer: Vitamin D may be used to boost anti-tumor activity, study finds - Montreal LeCanadian.com Magazine

PolitiFact | Tumors on deer in viral photo were not caused by Monsanto's Roundup

Glioma News, Research - Page 7

Tumor microenvironment remodeling in oral cancer: Application of plant derived-natural products and nanomaterials. | Environ...

A Molecular Signature Response Classifier to Predict Inadequate Response to Tumor Necrosis Factor-α Inhibitors: The NETWORK-004...

PTH Receptors - Targeting of KRAS mutant tumors by Inhibitors of Protease

Swarms of magnetic bacteria could be used to deliver drugs to tumors - Innovation Toronto

A Natural Approach To Mast Cell Tumors - Dogs Naturally

Issue | April 2017 | Targeting Tumors | The Scientist Magazine®

Novel Concepts Medical plant based formula has reversed the growth of cancer tumors - case studies report - Novel Concepts...

Microenvironment7

Malignant tumors3

Mice13

Tissues7

Types of tumors3

Significant inhibition of tumor growth1

Cancers7

Metastatic3

Genes5

Pediatric brain2

Biopsy4

Cancerous5

Cancer tumors1

Gastrointestinal2

Xenograft1

Ovarian6

Chemotherapy4

Anti-tumor activity2

Progression3

Diagnosis3

Cells and tumor3

Suppression1

Metastasis4

Prognosis1

Immune11

Cytotoxic3

Mammary6

Metabolism3

Apoptosis1

Researchers found1