PLANT EXTRACTS and compounds, primarily ISOFLAVONES, that mimic or modulate endogenous estrogens, usually by binding to ESTROGEN RECEPTORS.
Material prepared from plants.
3-Phenylchromones. Isomeric form of FLAVONOIDS in which the benzene group is attached to the 3 position of the benzopyran ring instead of the 2 position.
Non-steroidal compounds with estrogenic activity.
A daidzein derivative occurring naturally in forage crops which has some estrogenic activity.
A class of dibenzylbutane derivatives which occurs in higher plants and in fluids (bile, serum, urine, etc.) in man and other animals. These compounds, which have a potential anti-cancer role, can be synthesized in vitro by human fecal flora. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
An isoflavonoid derived from soy products. It inhibits PROTEIN-TYROSINE KINASE and topoisomerase-II (DNA TOPOISOMERASES, TYPE II); activity and is used as an antineoplastic and antitumor agent. Experimentally, it has been shown to induce G2 PHASE arrest in human and murine cell lines and inhibits PROTEIN-TYROSINE KINASE.
A non-steroidal ESTROGEN generated when soybean products are metabolized by certain bacteria in the intestines.
A plant genus of the family FABACEAE a common weed of the southeast US. There has been folk use for alcoholism and liver protection. It contains puerarin, kakkalide, daidzein (isoflavonoids), and kudzusaponins (oleanene-type triterpene glycosides).
An annual legume. The SEEDS of this plant are edible and used to produce a variety of SOY FOODS.
Proteins which are present in or isolated from SOYBEANS.
One of the ESTROGEN RECEPTORS that has greater affinity for ISOFLAVONES than ESTROGEN RECEPTOR ALPHA does. There is great sequence homology with ER alpha in the DNA-binding domain but not in the ligand binding and hinge domains.
Regular course of eating and drinking adopted by a person or animal.
One of the FURANS with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. It is also used as a pharmacological agent and solvent.
Compounds that interact with ESTROGEN RECEPTORS in target tissues to bring about the effects similar to those of ESTRADIOL. Estrogens stimulate the female reproductive organs, and the development of secondary female SEX CHARACTERISTICS. Estrogenic chemicals include natural, synthetic, steroidal, or non-steroidal compounds.
Cytoplasmic proteins that bind estrogens and migrate to the nucleus where they regulate DNA transcription. Evaluation of the state of estrogen receptors in breast cancer patients has become clinically important.
A non-steroidal estrogen analog.
Foods made from SOYBEANS. Health benefits are ascribed to the high levels of DIETARY PROTEINS and ISOFLAVONES.
A flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin.
An order of ungulates having an odd number of toes, including the horse, tapir, and rhinoceros. (Dorland, 27th ed)
One of the ESTROGEN RECEPTORS that has marked affinity for ESTRADIOL. Its expression and function differs from, and in some ways opposes, ESTROGEN RECEPTOR BETA.
A beverage prepared from SOYBEANS.
The 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids.
A genus of trees in the Lamiaceae family containing assorted flavonoids with possible analgesic and antineoplastic properties. The fruit of these trees is used in herbal preparations.
Compounds which inhibit or antagonize the action or biosynthesis of estrogenic compounds.
A sudden, temporary sensation of heat predominantly experienced by some women during MENOPAUSE. (Random House Unabridged Dictionary, 2d ed)
5,7,4'-trihydroxy-flavone, one of the FLAVONES.
The physiological period following the MENOPAUSE, the permanent cessation of the menstrual life.
A group of FLAVONOIDS characterized with a 4-ketone.
Ductless glands that secrete HORMONES directly into the BLOOD CIRCULATION. These hormones influence the METABOLISM and other functions of cells in the body.
Exogenous agents, synthetic and naturally occurring, which are capable of disrupting the functions of the ENDOCRINE SYSTEM including the maintenance of HOMEOSTASIS and the regulation of developmental processes. Endocrine disruptors are compounds that can mimic HORMONES, or enhance or block the binding of hormones to their receptors, or otherwise lead to activating or inhibiting the endocrine signaling pathways and hormone metabolism.
A white crystalline compound prepared by condensation of benzaldehyde in potassium cyanide and used in organic syntheses. This should not be confused with benzoin gum from STYRAX.
The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age.
A group of phenyl benzopyrans named for having structures like FLAVONES.
The external and internal organs related to reproduction.
A plant genus in the CANNABACEAE family. Best known for the buds of Humulus lupulus L. used in BEER.
The system of glands that release their secretions (hormones) directly into the circulatory system. In addition to the ENDOCRINE GLANDS, included are the CHROMAFFIN SYSTEM and the NEUROSECRETORY SYSTEMS.
The use of hormonal agents with estrogen-like activity in postmenopausal or other estrogen-deficient women to alleviate effects of hormone deficiency, such as vasomotor symptoms, DYSPAREUNIA, and progressive development of OSTEOPOROSIS. This may also include the use of progestational agents in combination therapy.
Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.
A plant genus of the family LINACEAE that is cultivated for its fiber (manufactured into linen cloth). It contains a trypsin inhibitor and the seed is the source of LINSEED OIL.
Tumors or cancer of the human BREAST.
The surgical removal of one or both ovaries.
Benzene derivatives that include one or more hydroxyl groups attached to the ring structure.
Benzopyrans saturated in the 2 and 3 positions.

Dietary isoflavones: biological effects and relevance to human health. (1/575)

Substantial evidence indicates that diets high in plant-based foods may explain the epidemiologic variance of many hormone-dependent diseases that are a major cause of mortality and morbidity in Western populations. There is now an increased awareness that plants contain many phytoprotectants. Lignans and isoflavones represent two of the main classes of phytoestrogens of current interest in clinical nutrition. Although ubiquitous in their occurrence in the plant kingdom, these bioactive nonnutrients are found in particularly high concentrations in flaxseeds and soybeans and have been found to have a wide range of hormonal and nonhormonal activities that serve to provide plausible mechanisms for the potential health benefits of diets rich in phytoestrogens. Data from animal and in vitro studies provide convincing evidence for the potential of phytoestrogens in influencing hormone-dependent states; although the clinical application of diets rich in these estrogen mimics is in its infancy, data from preliminary studies suggest beneficial effects of importance to health. This review focuses on the more recent studies pertinent to this field and includes, where appropriate, the landmark and historical literature that has led to the exponential increase in interest in phytoestrogens from a clinical nutrition perspective.  (+info)

Effects of soy or rye supplementation of high-fat diets on colon tumour development in azoxymethane-treated rats. (2/575)

Evidence is accumulating that a diet high in plant-derived foods may be protective against cancer. One class of plant component under increasing investigation is the phytoestrogens of which there are two main groups: the isoflavones, found mainly in soy products, and the lignans, which are more ubiquitous and are found in fruit, vegetables and cereals with high levels being found in flaxseed. In this study, we have used carefully balanced high-fat (40% energy) diets: a control diet (containing low isoflavone soy protein as the sole protein source), a rye diet (the control diet supplemented with rye bran) and a soy diet (containing as protein source a high isoflavone soy protein). The effect of these diets on the development of colonic cancer was studied in F-344 rats treated with the carcinogen, azoxymethane (two doses of 15 mg/kg given 1 week apart). Colons from treated animals were examined for aberrant crypt foci (ACF) and tumours after 12 and 31 weeks. Results after 12 weeks showed no differences in the total number of ACF in the control, soy or rye bran groups. However, the soy group had increased numbers of small ACF (less than four crypts/focus) while the rye group had decreased numbers of large ACF (greater than six crypts/focus). Examination of colons after 31 weeks gave similar low numbers of ACF in each group with no differences in multiplicity. There were no differences in the number of tumours between the control (1.36 tumours/rat) and soy (1.38 tumours/rat) groups. However, there was a significant decrease in the number of tumours in the rye group (0.17 tumours/rat). These results suggest that soy isoflavones have no effect on the frequency of colonic tumours in this model while rye bran supplementation decreases the frequency of colon cancer. This effect is due not to a decrease in early lesions but in their progression to larger multi-crypt ACF. The study also supports the hypothesis that larger ACF are more predictive of subsequent tumorigenicity.  (+info)

Incorporation of esterified soybean isoflavones with antioxidant activity into low density lipoprotein. (3/575)

We have recently reported that dietary intake of soybean isoflavone phytoestrogens resulted in increased oxidation resistance of isolated low density lipoprotein (LDL). In order to explore the underlying mechanisms we designed two types of in vitro experiments. First, we prepared several different isoflavone fatty acid esters to increase their lipid solubility and studied their incorporation into LDL. Second, the oxidation resistance of the isoflavone-containing LDLs was investigated with Esterbauer's 'conjugated diene' method using Cu2+ as prooxidant. Unesterified daidzein and genistein as well as genistein stearic acid esters were incorporated into LDL to a relatively small extent (0.33 molecules per LDL particle, or less) and they did not significantly influence oxidation resistance. The oleic acid esters of isoflavones were incorporated more effectively, reaching a level of 2.19 molecules per LDL particle or more, and the 4',7-O-dioleates of daidzein and genistein exhibited prolongations of lag times by 46% (P<0.05) and 202% (P<0.01), respectively. A smaller but significant increase in lag time (20.5%, P<0.01) was caused by daidzein 7-mono-oleate. In summary, esterification of soybean isoflavones daidzein and genistein with fatty acids at different hydroxyl groups provided lipophilicity needed for incorporation into LDL. Some isoflavone oleic acid esters increased oxidation resistance of LDL following their incorporation.  (+info)

trans-Resveratrol inhibits calcium influx in thrombin-stimulated human platelets. (4/575)

1. The phytoestrogenic compound trans-resveratrol (trans-3,5, 4'-trihydroxystilbene) is found in appreciable quantities in grape skins and wine. It has been shown that both products rich in trans-resveratrol and pure trans-resveratrol inhibit platelet aggregation both in vivo and in vitro. However the mechanism of this action still remains unknown. 2. An essential component of the aggregation process in platelets is an increase in intracellular free Ca2+ ([Ca2+]i). Ca2+ must enter the cell from the external media through specific and tightly regulated Ca2+ channels in the plasma membrane. The objective of this study was to characterize what effect trans-resveratrol had on the Ca2+ channels in thrombin stimulated platelets. 3. In this study we showed that trans-resveratrol immediately inhibited Ca2+ influx in thrombin-stimulated platelets with an IC50 of 0.5 microM. trans-Resveratrol at 0.1, 1.0 and 10.0 microM produced 20+/-6, 37+/-6 and 57+/-4% inhibition respectively of the effect of thrombin (0.01 u ml(-1)) to increase [Ca2+]i. 4. trans-Resveratrol also inhibited spontaneous Ba2+ entry into Fura-2 loaded platelets, with 0.1, 1.0 and 10.0 microM trans-resveratrol producing 10+/-5, 30+/-5 and 50+/-7% inhibition respectively. This indicated that trans-resveratrol directly inhibited Ca2+ channel activity in the platelets in the absence of agonist stimulation. 5. trans-Resveratrol also inhibited thapsigargin-mediated Ca2+ influx into platelets. This suggests that the store-operated Ca2+ channels are one of the possible targets of trans-resveratrol. These channels rely on the emptying of the internal Ca2+ stores to initiate influx of Ca2+ into the cell. 6. The phytoestrogens genistein, daidzein, apigenin and genistein-glucoside (genistin) produced inhibitory effects against thrombin similar to those seen with trans-resveratrol. 7. We conclude that trans-resveratrol is an inhibitor of store-operated Ca2+ channels in human platelets. This accounts for the ability of trans-resveratrol to inhibit platelet aggregation induced by thrombin.  (+info)

Xeno-oestrogens and phyto-oestrogens induce the synthesis of leukaemia inhibitory factor by human and bovine oviduct cells. (5/575)

In bovine oviduct cells 17beta-oestradiol can induce the synthesis of leukaemia inhibitory factor (LIF), a glycoprotein essential for embryo implantation. Therefore substances which are structurally similar to 17beta-oestradiol and possess oestrogenic activity may also modulate LIF synthesis and influence the reproductive process. We used primary cultures of bovine and human oviduct cells (epithelial cells:fibroblasts 1:1) to compare the effects of 17beta-oestradiol, phyto-oestrogens (genistein, biochanin A, daidzein, formononetin, and equol) and xeno-oestrogens [polychlorinated biphenyls (PCB): trichlorobiphenyl, 4-hydroxy-trichlorobiphenyl and 4-hydroxy-dichlorobiphenyl] on LIF synthesis. Immunoreactive LIF-enzyme-linked immunosorbent assay was used to determine the concentration of LIF in the culture medium. Similar to 17beta-oestradiol, genistein (0.02-2 micromol/l) induced LIF synthesis in bovine oviduct cells in a concentration-dependent manner. Equol, biochanin A and daidzein (2 micromol/l), 4-hydroxy-trichlorobiphenyl and 4-hydroxy-dichlorobiphenyl (0.01-10 micromol/l) but not formononetin (2 micromol/l) also induced LIF synthesis in bovine cells. Phyto-oestrogens and xeno-oestrogens also induced LIF synthesis in human oviduct cells (P < 0.05). The stimulatory effects of PCB, phyto-oestrogens and 17beta-oestradiol were blocked by ICI 182,780 (1 micromol/l). Moreover, 17beta-oestradiol, 4-hydroxy-trichlorobiphenyl, 4-hydroxy-dichlorobiphenyl, genistein, tamoxifen and ICI 182,780 displaced [(3)H]17beta-oestradiol from cytosolic oestrogen receptors in bovine oviduct cells. These results suggest that phyto-oestrogens and PCB mimic the effects of oestradiol in inducing LIF synthesis by bovine and human oviduct cells and that these stimulatory effects are oestrogen receptor-mediated. Environmental oestrogens act as endocrine modulators/disrupters and may induce deleterious effects on the reproductive process by influencing LIF synthesis in a non-cyclic fashion leading to tubal infertility.  (+info)

Evaluation of soy phytoestrogens for the treatment of hot flashes in breast cancer survivors: A North Central Cancer Treatment Group Trial. (6/575)

PURPOSE: Hot flashes represent a significant clinical problem for some breast cancer survivors. Safe, effective treatment is needed for this prominent clinical problem. Although it has been shown that estrogen or progesterone replacement therapy can alleviate this problem, there are continued safety concerns regarding the use of hormonal therapies in these women. Based on anecdotal information, we hypothesized that soy-derived phytoestrogens, weak estrogen-like substances in the soybean that demonstrate estrogen agonist and/or antagonist effects when they bind to estrogen receptors, could alleviate hot flashes. This current trial was designed to investigate this hypothesis. PATIENTS AND METHODS: This double-blind clinical trial involved breast cancer survivors with substantial hot flashes. After randomization, patients underwent a 1-week baseline period with no therapy. This was followed by 4 weeks of either soy tablets or placebo. The patients then crossed over to the opposite arm in a double-blind manner for the last 4 weeks. Patients completed a daily questionnaire documenting hot flash frequency, intensity, and perceived side effects. RESULTS: Of the 177 women who were randomized and started the study substance, 155 (88%) provided useable data over the first 5 weeks; 149 provided usable data over the entire 9 weeks. There was no suggestion that the soy product was more effective in reducing hot flashes than the placebo. At study completion, patients preferred the soy product 33% of the time, the placebo 37% of the time, and neither substance 31% of the time. No toxicity was observed. CONCLUSION: The soy product did not alleviate hot flashes in breast cancer survivors.  (+info)

Comparison of isoflavones among dietary intake, plasma concentration and urinary excretion for accurate estimation of phytoestrogen intake. (7/575)

Biological effects of dietary isoflavones, such as daidzein and genistein are of interest in preventive medicine. We estimated the dietary intake of isoflavones from dietary records and compared the values with the plasma concentrations and urinary excretions in Japanese middle-aged women. The dietary intake of daidzein and genistein was 64.6 and 111.6 mumol /day/capita (16.4 and 30.1 mg/day/capita), respectively. The isoflavones intake was mostly attributable to tofu, natto and miso. The median of plasma daidzein and genistein concentration was 72.46 and 206.09 nmol/L, respectively. The median of urinary excretion was 20.54 mumol /day for daidzein, 10.79 for genistein, 15.74 for equol and 1.64 for O-desmethylangolensin (O-DMA). Equol and O-DMA were excreted by 50% and 84% of all participants, respectively. Equol metabolizers were significantly lower the plasma and urinary daidzein and urinary O-DMA. The dietary intake of daidzein and genistein after the adjustment for total energy intake was significantly correlated with the urinary excretion (r = 0.365 for daidzein and r = 0.346 for genistein) and plasma concentration (r = 0.335 for daidzein and r = 0.429 for genistein). The plasma concentration of isoflavones was also significantly correlated with the urinary excretion. We conclude that in epidemiological studies measurements of plasma concentration or urinary excretion of these isoflavones are useful biomarkers of dietary intake and important for studies on their relation to human health.  (+info)

Phytoestrogens and cardiovascular health. (8/575)

Coronary artery disease is the leading overall cause of mortality for women and increases dramatically after menopause. Estrogen has many beneficial cardiovascular actions although concerns have been raised about its effects on the progression of breast and uterine neoplasms and its tendency to increase coagulability. Selective estrogen agonists may be superior to conventional estrogens. A dietary source of a partial estrogen agonist is the plant-based group of phytoestrogens, which include isoflavones, lignans and coumestans. Phytoestrogens have a similar structure to estradiol and have weak affinity for the estrogen receptor. Epidemiologic data indicate that women ingesting high amounts of phytoestrogens, particularly as isoflavones in soy products, have less cardiovascular disease, breast and uterine cancer and menopausal symptoms than those eating Western diets. Preclinical and clinical studies have found that isoflavones have lipid-lowering effects as well as the ability to inhibit low-density lipoprotein oxidation. They have been shown to normalize vascular reactivity in estrogen-deprived primates. Furthermore, phytoestrogens have antineoplastic effects with inhibition of cellular proliferation as well as angiogenesis, properties that could be protective against cancer development. Finally, menopausal symptoms and bone density may be favorably influenced by phytoestrogens. In summary, phytoestrogens, in the form of dietary isoflavones, represent a new area to explore in pursuit of nutritional approaches to cardiovascular protection.  (+info)

Phytoestrogens are compounds found in plants that have estrogen-like properties. They can bind to and activate or inhibit the action of estrogen receptors in the body, depending on their structure and concentration. Phytoestrogens are present in a variety of foods, including soy products, nuts, seeds, fruits, and vegetables.

Phytoestrogens have been studied for their potential health benefits, such as reducing the risk of hormone-dependent cancers (e.g., breast cancer), improving menopausal symptoms, and promoting bone health. However, their effects on human health are complex and not fully understood, and some studies suggest that high intake of phytoestrogens may have adverse effects in certain populations or under specific conditions.

It is important to note that while phytoestrogens can mimic the effects of estrogen in the body, they are generally weaker than endogenous estrogens produced by the human body. Therefore, their impact on hormonal balance and health outcomes may vary depending on individual factors such as age, sex, hormonal status, and overall diet.

"Plant preparations" is not a term with a specific medical definition in the field of medicine or pharmacology. However, it is commonly used to refer to various forms of plant material that have been prepared for medicinal use. This can include dried and powdered plant parts, such as leaves, roots, or flowers, as well as extracts or concentrates made from plants. These preparations may be used in traditional medicine or as the basis for modern pharmaceuticals. It is important to note that the safety, effectiveness, and quality of plant preparations can vary widely, and they should only be used under the guidance of a qualified healthcare provider.

Isoflavones are a type of plant-derived compounds called phytoestrogens, which have a chemical structure similar to human estrogen. They are found in various plants, particularly in soybeans and soy products. Isoflavones can act as weak estrogens or anti-estrogens in the body, depending on the levels of natural hormones present. These compounds have been studied for their potential health benefits, including reducing menopausal symptoms, improving cardiovascular health, and preventing certain types of cancer. However, more research is needed to fully understand their effects and safety.

Non-steroidal estrogens are a class of compounds that exhibit estrogenic activity but do not have a steroid chemical structure. They are often used in hormone replacement therapy and to treat symptoms associated with menopause. Examples of non-steroidal estrogens include:

1. Phytoestrogens: These are plant-derived compounds that have estrogenic activity. They can be found in various foods such as soy, nuts, seeds, and some fruits and vegetables.
2. Selective Estrogen Receptor Modulators (SERMs): These are synthetic compounds that act as estrogen receptor agonists or antagonists, depending on the target tissue. Examples include tamoxifen, raloxifene, and toremifene. They are used in the treatment of breast cancer and osteoporosis.
3. Designer Estrogens: These are synthetic compounds that have been specifically designed to mimic the effects of estrogen. They are often used in research but have not been approved for clinical use.

It is important to note that non-steroidal estrogens can also have side effects and risks, including an increased risk of certain types of cancer, cardiovascular disease, and thromboembolic events. Therefore, their use should be carefully monitored and managed by a healthcare professional.

Coumestrol is a type of phytoestrogen, which is a plant-derived compound that can mimic the effects of estrogen in the body. It belongs to a class of compounds called coumestans and is found in various plants such as clover, alfalfa, and soybeans. Coumestrol has weak estrogenic activity and can bind to estrogen receptors in the body, potentially affecting hormonal balance and having both estrogenic and anti-estrogenic effects. It has been studied for its potential effects on various health conditions, including cancer, osteoporosis, and cardiovascular disease.

Lignans are a type of plant compound that have antioxidant and estrogen properties. They are found in various plants such as seeds, grains, fruits, and vegetables. Once consumed, some lignans can be converted by intestinal bacteria into enterolactone and enterodiol, which can have weak estrogenic or anti-estrogenic effects in the body. These compounds have been studied for their potential health benefits, including reducing the risk of cancer and heart disease. However, more research is needed to fully understand their effects and potential health benefits.

Genistein is defined as a type of isoflavone, which is a plant-derived compound with estrogen-like properties. It is found in soybeans and other legumes. Genistein acts as a phytoestrogen, meaning it can bind to estrogen receptors and have both weak estrogenic and anti-estrogenic effects in the body.

In addition to its estrogenic activity, genistein has been found to have various biological activities, such as antioxidant, anti-inflammatory, and anticancer properties. It has been studied for its potential role in preventing or treating a variety of health conditions, including cancer, cardiovascular disease, osteoporosis, and menopausal symptoms. However, more research is needed to fully understand the potential benefits and risks of genistein supplementation.

Equol is a metabolite produced by intestinal bacteria that can metabolize the soy isoflavone daidzein. It has been studied for its potential role in various health outcomes, such as reducing menopause symptoms and protecting against certain types of cancer. However, not all individuals have the ability to produce equol, and its effects on human health are still a subject of ongoing research.

"Pueraria" is a genus of plants in the legume family, Fabaceae. The most commonly known species is Pueraria lobata, also called kudzu or Japanese arrowroot. This plant is native to East Asia and has been used in traditional medicine for various purposes such as treating alcoholism, fever, and inflammation.

In a medical context, "Pueraria" may refer to the use of extracts from this plant in dietary supplements or alternative medicine practices. Some studies have suggested that certain compounds found in Pueraria, such as isoflavones, may have potential health benefits, but more research is needed to confirm these effects and establish safe and effective dosages.

It's important to note that while some natural products containing Pueraria extracts may be marketed for various health purposes, they should not be used as a substitute for conventional medical care or treatment. It's always best to consult with a healthcare provider before starting any new supplement regimen.

I'm sorry for any confusion, but "soybeans" are not a medical term. They are a type of legume that is commonly used in agriculture and food production. The medical community might discuss soybeans in the context of nutrition or allergies, but there isn't a formal medical definition for this term.

Here's some general information: Soybeans, scientifically known as Glycine max, are native to East Asia and are now grown worldwide. They are a significant source of plant-based protein and oil. Soybeans contain various nutrients, including essential amino acids, fiber, B vitamins, and minerals like calcium, iron, magnesium, and zinc. They are used in various food products such as tofu, soy milk, tempeh, and miso. Additionally, soybeans are also used in the production of industrial products, including biodiesel, plastics, and inks. Some people may have allergic reactions to soybeans or soy products.

Soybean proteins are the proteins derived from soybeans, a legume native to East Asia. Soybeans contain approximately 40% protein by weight, making them a significant source of plant-based protein. The two major types of soy protein are:

1. Soy protein isolate (SPI): This is a highly refined protein that contains at least 90% protein by weight. It is made by removing carbohydrates and fiber from defatted soy flour, leaving behind a protein-rich powder. SPI is often used as an ingredient in various food products, including meat alternatives, energy bars, and beverages.
2. Soy protein concentrate (SPC): This type of soy protein contains approximately 70% protein by weight. It is made by removing some of the carbohydrates from defatted soy flour, leaving behind a higher concentration of proteins. SPC has applications in food and industrial uses, such as in textured vegetable protein (TVP) for meat alternatives, baked goods, and functional foods.

Soy proteins are considered high-quality proteins due to their complete amino acid profile, containing all nine essential amino acids necessary for human nutrition. They also have various health benefits, such as lowering cholesterol levels, improving bone health, and promoting muscle growth and maintenance. However, it is important to note that soy protein consumption should be balanced with other protein sources to ensure a diverse intake of nutrients.

Estrogen Receptor beta (ER-β) is a protein that is encoded by the gene ESR2 in humans. It belongs to the family of nuclear receptors, which are transcription factors that regulate gene expression in response to hormonal signals. ER-β is one of two main estrogen receptors, the other being Estrogen Receptor alpha (ER-α), and it plays an important role in mediating the effects of estrogens in various tissues, including the breast, uterus, bone, brain, and cardiovascular system.

Estrogens are steroid hormones that play a critical role in the development and maintenance of female reproductive and sexual function. They also have important functions in other tissues, such as maintaining bone density and promoting cognitive function. ER-β is widely expressed in many tissues, including those outside of the reproductive system, suggesting that it may have diverse physiological roles beyond estrogen-mediated reproduction.

ER-β has been shown to have both overlapping and distinct functions from ER-α, and its expression patterns differ between tissues. For example, in the breast, ER-β is expressed at higher levels in normal tissue compared to cancerous tissue, suggesting that it may play a protective role against breast cancer development. In contrast, in the uterus, ER-β has been shown to have anti-proliferative effects and may protect against endometrial cancer.

Overall, ER-β is an important mediator of estrogen signaling and has diverse physiological roles in various tissues. Understanding its functions and regulation may provide insights into the development of novel therapies for a range of diseases, including cancer, osteoporosis, and cardiovascular disease.

A diet, in medical terms, refers to the planned and regular consumption of food and drinks. It is a balanced selection of nutrient-rich foods that an individual eats on a daily or periodic basis to meet their energy needs and maintain good health. A well-balanced diet typically includes a variety of fruits, vegetables, whole grains, lean proteins, and low-fat dairy products.

A diet may also be prescribed for therapeutic purposes, such as in the management of certain medical conditions like diabetes, hypertension, or obesity. In these cases, a healthcare professional may recommend specific restrictions or modifications to an individual's regular diet to help manage their condition and improve their overall health.

It is important to note that a healthy and balanced diet should be tailored to an individual's age, gender, body size, activity level, and any underlying medical conditions. Consulting with a healthcare professional, such as a registered dietitian or nutritionist, can help ensure that an individual's dietary needs are being met in a safe and effective way.

4-Butyrolactone, also known as gamma-butyrolactone (GBL) or 1,4-butanolide, is a chemical compound with the formula C4H6O2. It is a colorless oily liquid that is used in various industrial and commercial applications, including as an intermediate in the production of other chemicals, as a solvent, and as a flavoring agent.

In the medical field, 4-butyrolactone has been studied for its potential use as a sleep aid and muscle relaxant. However, it is not currently approved by regulatory agencies such as the US Food and Drug Administration (FDA) for these uses. It is also known to have abuse potential and can cause intoxication, sedation, and other central nervous system effects when ingested or inhaled.

It's important to note that 4-butyrolactone is not a medication and should only be used under the supervision of a qualified healthcare professional for approved medical purposes.

Estrogens are a group of steroid hormones that are primarily responsible for the development and regulation of female sexual characteristics and reproductive functions. They are also present in lower levels in males. The main estrogen hormone is estradiol, which plays a key role in promoting the growth and development of the female reproductive system, including the uterus, fallopian tubes, and breasts. Estrogens also help regulate the menstrual cycle, maintain bone density, and have important effects on the cardiovascular system, skin, hair, and cognitive function.

Estrogens are produced primarily by the ovaries in women, but they can also be produced in smaller amounts by the adrenal glands and fat cells. In men, estrogens are produced from the conversion of testosterone, the primary male sex hormone, through a process called aromatization.

Estrogen levels vary throughout a woman's life, with higher levels during reproductive years and lower levels after menopause. Estrogen therapy is sometimes used to treat symptoms of menopause, such as hot flashes and vaginal dryness, or to prevent osteoporosis in postmenopausal women. However, estrogen therapy also carries risks, including an increased risk of certain cancers, blood clots, and stroke, so it is typically recommended only for women who have a high risk of these conditions.

Estrogen receptors (ERs) are a type of nuclear receptor protein that are expressed in various tissues and cells throughout the body. They play a critical role in the regulation of gene expression and cellular responses to the hormone estrogen. There are two main subtypes of ERs, ERα and ERβ, which have distinct molecular structures, expression patterns, and functions.

ERs function as transcription factors that bind to specific DNA sequences called estrogen response elements (EREs) in the promoter regions of target genes. When estrogen binds to the ER, it causes a conformational change in the receptor that allows it to recruit co-activator proteins and initiate transcription of the target gene. This process can lead to a variety of cellular responses, including changes in cell growth, differentiation, and metabolism.

Estrogen receptors are involved in a wide range of physiological processes, including the development and maintenance of female reproductive tissues, bone homeostasis, cardiovascular function, and cognitive function. They have also been implicated in various pathological conditions, such as breast cancer, endometrial cancer, and osteoporosis. As a result, ERs are an important target for therapeutic interventions in these diseases.

Zeranol is not a medical term per se, but it is a chemical compound used in veterinary medicine and agriculture. Zeranol is a non-steroidal estrogenic growth promoter, which means it is used to promote growth in animals, particularly cattle. It belongs to the class of compounds known as zearalenones, which are mycotoxins produced by certain types of fungi.

Zeranol works by binding to estrogen receptors in the animal's body, mimicking the effects of natural estrogens and promoting growth. It is important to note that zeranol is not approved for use in humans, and its potential health effects on humans are not well understood. However, residues of zeranol have been found in meat products derived from cattle treated with the compound, leading to concerns about its potential impact on human health.

Soy foods are food products made from soybeans, which are a rich source of plant-based protein, fiber, and various beneficial compounds like isoflavones. Examples of soy foods include tofu, tempeh, soymilk, edamame (immature soybeans), soy flour, and textured vegetable protein (TVP). Soy products can be used as alternatives to animal-based proteins and can be incorporated into a variety of dishes, such as stir-fries, soups, smoothies, and baked goods. It's important to note that some people may have allergies to soy or sensitivities to its phytoestrogens, which can affect hormone balance in the body.

Quercetin is a type of flavonoid antioxidant that is found in plant foods, including leafy greens, tomatoes, berries, and broccoli. It has been studied for its potential health benefits, such as reducing inflammation, protecting against damage to cells, and helping to reduce the risk of heart disease and cancer. Quercetin is also known for its ability to stabilize mast cells and prevent the release of histamine, making it a popular natural remedy for allergies. It is available in supplement form, but it is always recommended to consult with a healthcare provider before starting any new supplement regimen.

Perissodactyla is not a medical term, but rather a taxonomic order in zoology. It includes mammals with an odd number of toes on each foot and a particular type of digestive system called "hindgut fermentation." The order Perissodactyla includes horses, rhinos, and tapirs.

Estrogen Receptor alpha (ERα) is a type of nuclear receptor protein that is activated by the hormone estrogen. It is encoded by the gene ESR1 and is primarily expressed in the cells of the reproductive system, breast, bone, liver, heart, and brain tissue.

When estrogen binds to ERα, it causes a conformational change in the receptor, which allows it to dimerize and translocate to the nucleus. Once in the nucleus, ERα functions as a transcription factor, binding to specific DNA sequences called estrogen response elements (EREs) and regulating the expression of target genes.

ERα plays important roles in various physiological processes, including the development and maintenance of female reproductive organs, bone homeostasis, and lipid metabolism. It is also a critical factor in the growth and progression of certain types of breast cancer, making ERα status an important consideration in the diagnosis and treatment of this disease.

Soy milk is not a medical term, but it is a common term used to describe a plant-based milk alternative made from soybeans. Here's a brief description:

Soy milk is a beverage produced by soaking and grinding soybeans, then filtering the resulting mixture to remove solid particles. It is often consumed as a dairy substitute by individuals who are lactose intolerant or have milk allergies. Soy milk contains protein, carbohydrates, and fat, similar to cow's milk, but its nutritional profile may vary depending on the manufacturing process. Some brands of soy milk are fortified with calcium, vitamins B12, D, and riboflavin (B2) to resemble the nutritional content of cow's milk.

Please note that while soy milk can be a healthy alternative for many people, it may not be suitable for everyone, especially those with soy allergies or sensitivities. If you have any concerns about incorporating soy milk into your diet, consult a healthcare professional or a registered dietitian.

Estradiol is a type of estrogen, which is a female sex hormone. It is the most potent and dominant form of estrogen in humans. Estradiol plays a crucial role in the development and maintenance of secondary sexual characteristics in women, such as breast development and regulation of the menstrual cycle. It also helps maintain bone density, protect the lining of the uterus, and is involved in cognition and mood regulation.

Estradiol is produced primarily by the ovaries, but it can also be synthesized in smaller amounts by the adrenal glands and fat cells. In men, estradiol is produced from testosterone through a process called aromatization. Abnormal levels of estradiol can contribute to various health issues, such as hormonal imbalances, infertility, osteoporosis, and certain types of cancer.

Vitex, also known as chasteberry or Vitex agnus-castus, is not a medical term but a common herbal supplement. It is derived from the fruit of the Vitex agnus-castus tree, which is native to the Mediterranean region and parts of Asia.

The medical community has studied Vitex for its potential effects on various conditions, including premenstrual syndrome (PMS), menopausal symptoms, and irregular menstrual cycles. However, it's essential to note that the evidence supporting its use is mixed, and more research is needed to confirm its effectiveness and safety.

Vitex is thought to have dopamine-like effects on the hypothalamus, which may help regulate hormonal imbalances in some women. However, it can interact with other medications and has potential side effects, so it's crucial to consult a healthcare provider before taking Vitex or any herbal supplement.

Estrogen antagonists, also known as antiestrogens, are a class of drugs that block the effects of estrogen in the body. They work by binding to estrogen receptors and preventing the natural estrogen from attaching to them. This results in the inhibition of estrogen-mediated activities in various tissues, including breast and uterine tissue.

There are two main types of estrogen antagonists: selective estrogen receptor modulators (SERMs) and pure estrogen receptor downregulators (PERDS), also known as estrogen receptor downregulators (ERDs). SERMs, such as tamoxifen and raloxifene, can act as estrogen agonists or antagonists depending on the tissue type. For example, they may block the effects of estrogen in breast tissue while acting as an estrogen agonist in bone tissue, helping to prevent osteoporosis.

PERDS, such as fulvestrant, are pure estrogen receptor antagonists and do not have any estrogen-like activity. They are used primarily for the treatment of hormone receptor-positive breast cancer in postmenopausal women.

Overall, estrogen antagonists play an important role in the management of hormone receptor-positive breast cancer and other conditions where inhibiting estrogen activity is beneficial.

A hot flash is a sudden, intense feeling of heat, particularly in the face, neck and chest regions, which is often accompanied by perspiration, reddening of the skin (flush or blush), and rapid heartbeat. It is a common symptom experienced by individuals, especially women during menopause or perimenopause, although it can also occur in other medical conditions or as a side effect of certain medications. The exact cause of hot flashes is not fully understood, but they are thought to be related to changes in hormone levels and the body's regulation of temperature.

Apigenin is a flavonoid, which is a type of plant pigment that is responsible for the color of many fruits and vegetables. It is found in various plants such as chamomile, parsley, celery, and citrus fruits. Apigenin has been studied for its potential health benefits, including anti-cancer, anti-inflammatory, and neuroprotective effects. However, more research is needed to confirm these potential benefits and determine the safe and effective dosage for human use.

Postmenopause is a stage in a woman's life that follows 12 months after her last menstrual period (menopause) has occurred. During this stage, the ovaries no longer release eggs and produce lower levels of estrogen and progesterone hormones. The reduced levels of these hormones can lead to various physical changes and symptoms, such as hot flashes, vaginal dryness, and mood changes. Postmenopause is also associated with an increased risk of certain health conditions, including osteoporosis and heart disease. It's important for women in postmenopause to maintain a healthy lifestyle, including regular exercise, a balanced diet, and routine medical check-ups to monitor their overall health and manage any potential risks.

Flavanones are a type of flavonoid, which is a class of plant pigments widely found in fruits, vegetables, and other plants. Flavanones are known for their antioxidant properties and potential health benefits. They are typically found in citrus fruits such as oranges, lemons, and grapefruits. Some common flavanones include hesperetin, naringenin, and eriodictyol. These compounds have been studied for their potential effects on cardiovascular health, cancer prevention, and neuroprotection, although more research is needed to fully understand their mechanisms of action and therapeutic potential.

Endocrine glands are ductless glands in the human body that release hormones directly into the bloodstream, which then carry the hormones to various tissues and organs in the body. These glands play a crucial role in regulating many of the body's functions, including metabolism, growth and development, tissue function, sexual function, reproduction, sleep, and mood.

Examples of endocrine glands include the pituitary gland, thyroid gland, parathyroid glands, adrenal glands, pineal gland, pancreas, ovaries, and testes. Each of these glands produces specific hormones that have unique effects on various target tissues in the body.

The endocrine system works closely with the nervous system to regulate many bodily functions through a complex network of feedback mechanisms. Disorders of the endocrine system can result in a wide range of symptoms and health problems, including diabetes, thyroid disease, growth disorders, and sexual dysfunction.

Endocrine disruptors are defined as exogenous (external) substances or mixtures that interfere with the way hormones work in the body, leading to negative health effects. They can mimic, block, or alter the normal synthesis, secretion, transport, binding, action, or elimination of natural hormones in the body responsible for maintaining homeostasis, reproduction, development, and/or behavior.

Endocrine disruptors can be found in various sources, including industrial chemicals, pesticides, pharmaceuticals, and personal care products. They have been linked to a range of health problems, such as cancer, reproductive issues, developmental disorders, neurological impairments, and immune system dysfunction.

Examples of endocrine disruptors include bisphenol A (BPA), phthalates, dioxins, polychlorinated biphenyls (PCBs), perfluoroalkyl substances (PFAS), and certain pesticides like dichlorodiphenyltrichloroethane (DDT) and vinclozolin.

It is important to note that endocrine disruptors can have effects at very low doses, and their impact may depend on the timing of exposure, particularly during critical windows of development such as fetal growth and early childhood.

Benzoin, in a medical context, most commonly refers to a type of compound called a benzoin resin or benzoin tincture, which is derived from the bark of certain trees in the genus Styrax. It has been used traditionally in medicine for its antiseptic and expectorant properties.

Benzoin resin is obtained by making incisions in the bark of the tree and allowing the resin to exude and harden. The solidified resin is then collected and may be ground into a powder or dissolved in alcohol to create a tincture.

Benzoin tincture has been used topically as an antiseptic and to help heal wounds, ulcers, and burns. It has also been used as an expectorant to help clear respiratory congestion and coughs.

It is important to note that benzoin should be used with caution, as it can cause skin irritation and allergic reactions in some people. Additionally, benzoin tincture contains a significant amount of alcohol and should not be taken internally without the guidance of a healthcare professional.

Menopause is a natural biological process that typically occurs in women in their mid-40s to mid-50s. It marks the end of menstrual cycles and fertility, defined as the absence of menstruation for 12 consecutive months. This transition period can last several years and is often accompanied by various physical and emotional symptoms such as hot flashes, night sweats, mood changes, sleep disturbances, and vaginal dryness. The hormonal fluctuations during this time, particularly the decrease in estrogen levels, contribute to these symptoms. It's essential to monitor and manage these symptoms to maintain overall health and well-being during this phase of life.

Flavonoids are a type of plant compounds with antioxidant properties that are beneficial to health. They are found in various fruits, vegetables, grains, and wine. Flavonoids have been studied for their potential to prevent chronic diseases such as heart disease and cancer due to their ability to reduce inflammation and oxidative stress.

There are several subclasses of flavonoids, including:

1. Flavanols: Found in tea, chocolate, grapes, and berries. They have been shown to improve blood flow and lower blood pressure.
2. Flavones: Found in parsley, celery, and citrus fruits. They have anti-inflammatory and antioxidant properties.
3. Flavanonols: Found in citrus fruits, onions, and tea. They have been shown to improve blood flow and reduce inflammation.
4. Isoflavones: Found in soybeans and legumes. They have estrogen-like effects and may help prevent hormone-related cancers.
5. Anthocyanidins: Found in berries, grapes, and other fruits. They have antioxidant properties and may help improve vision and memory.

It is important to note that while flavonoids have potential health benefits, they should not be used as a substitute for medical treatment or a healthy lifestyle. It is always best to consult with a healthcare professional before starting any new supplement regimen.

Genitalia, also known as the genitals, refer to the reproductive organs located in the pelvic region. In males, these include the penis and testicles, while in females, they consist of the vulva, vagina, clitoris, and ovaries. Genitalia are essential for sexual reproduction and can also be associated with various medical conditions, such as infections, injuries, or congenital abnormalities.

"Humulus" is a term that refers to a genus of plants, specifically the hop plant. The hop plant belongs to the Cannabaceae family and is native to Europe, western Asia, and North America. The humulus plant has climbing or trailing stems and produces separate male and female flowers on different plants.

The female flowers, known as hops, are used in the brewing industry to add flavor, aroma, and preservative qualities to beer. Hops contain resins and essential oils that contribute to the bitter taste and floral or citrusy notes of beer. They also have antibacterial properties that help to stabilize and preserve the beverage.

In a medical context, hops are sometimes used in herbal medicine for their sedative and calming effects. They may be prepared as teas, tinctures, or extracts and can be used to treat anxiety, insomnia, restlessness, and other conditions related to nervous tension. However, it's important to note that the scientific evidence supporting these uses is limited, and hops should not be used as a substitute for medical treatment without consulting a healthcare professional.

The endocrine system is a complex network of glands and organs that produce, store, and secrete hormones. It plays a crucial role in regulating various functions and processes in the body, including metabolism, growth and development, tissue function, sexual function, reproduction, sleep, and mood.

The major endocrine glands include:

1. Pituitary gland: located at the base of the brain, it is often referred to as the "master gland" because it controls other glands' functions. It produces and releases several hormones that regulate growth, development, and reproduction.
2. Thyroid gland: located in the neck, it produces hormones that regulate metabolism, growth, and development.
3. Parathyroid glands: located near the thyroid gland, they produce parathyroid hormone, which regulates calcium levels in the blood.
4. Adrenal glands: located on top of the kidneys, they produce hormones that regulate stress response, metabolism, and blood pressure.
5. Pancreas: located in the abdomen, it produces hormones such as insulin and glucagon that regulate blood sugar levels.
6. Sex glands (ovaries and testes): they produce sex hormones such as estrogen, progesterone, and testosterone that regulate sexual development and reproduction.
7. Pineal gland: located in the brain, it produces melatonin, a hormone that regulates sleep-wake cycles.

The endocrine system works closely with the nervous system to maintain homeostasis or balance in the body's internal environment. Hormones are chemical messengers that travel through the bloodstream to target cells or organs, where they bind to specific receptors and elicit a response. Disorders of the endocrine system can result from overproduction or underproduction of hormones, leading to various health problems such as diabetes, thyroid disorders, growth disorders, and sexual dysfunction.

Estrogen Replacement Therapy (ERT) is a medical treatment in which estrogen hormones are administered to replace the estrogen that is naturally produced by the ovaries but declines, especially during menopause. This therapy is often used to help manage symptoms of menopause such as hot flashes, night sweats, and vaginal dryness. It can also help prevent bone loss in postmenopausal women. ERT typically involves the use of estrogen alone, but in some cases, a combination of estrogen and progestin may be prescribed for women with a uterus to reduce the risk of endometrial cancer. However, ERT is associated with certain risks, including an increased risk of breast cancer, blood clots, and stroke, so it's important for women to discuss the potential benefits and risks with their healthcare provider before starting this therapy.

A plant extract is a preparation containing chemical constituents that have been extracted from a plant using a solvent. The resulting extract may contain a single compound or a mixture of several compounds, depending on the extraction process and the specific plant material used. These extracts are often used in various industries including pharmaceuticals, nutraceuticals, cosmetics, and food and beverage, due to their potential therapeutic or beneficial properties. The composition of plant extracts can vary widely, and it is important to ensure their quality, safety, and efficacy before use in any application.

I apologize for any confusion, but "flax" is not a medical term. It is actually a type of plant also known as Linum usitatissimum. The seeds of the flax plant are used in making linseed oil, and flax fibers are used to make linen. Flaxseeds are often consumed for their health benefits, as they are rich in omega-3 fatty acids, fiber, and lignans. If you have any questions about the use of flax or its components in a medical context, I would be happy to try to help further.

Breast neoplasms refer to abnormal growths in the breast tissue that can be benign or malignant. Benign breast neoplasms are non-cancerous tumors or growths, while malignant breast neoplasms are cancerous tumors that can invade surrounding tissues and spread to other parts of the body.

Breast neoplasms can arise from different types of cells in the breast, including milk ducts, milk sacs (lobules), or connective tissue. The most common type of breast cancer is ductal carcinoma, which starts in the milk ducts and can spread to other parts of the breast and nearby structures.

Breast neoplasms are usually detected through screening methods such as mammography, ultrasound, or MRI, or through self-examination or clinical examination. Treatment options for breast neoplasms depend on several factors, including the type and stage of the tumor, the patient's age and overall health, and personal preferences. Treatment may include surgery, radiation therapy, chemotherapy, hormone therapy, or targeted therapy.

Ovariectomy is a surgical procedure in which one or both ovaries are removed. It is also known as "ovary removal" or "oophorectomy." This procedure is often performed as a treatment for various medical conditions, including ovarian cancer, endometriosis, uterine fibroids, and pelvic pain. Ovariectomy can also be part of a larger surgical procedure called an hysterectomy, in which the uterus is also removed.

In some cases, an ovariectomy may be performed as a preventative measure for individuals at high risk of developing ovarian cancer. This is known as a prophylactic ovariectomy. After an ovariectomy, a person will no longer have menstrual periods and will be unable to become pregnant naturally. Hormone replacement therapy may be recommended in some cases to help manage symptoms associated with the loss of hormones produced by the ovaries.

Phenols, also known as phenolic acids or phenol derivatives, are a class of chemical compounds consisting of a hydroxyl group (-OH) attached to an aromatic hydrocarbon ring. In the context of medicine and biology, phenols are often referred to as a type of antioxidant that can be found in various foods and plants.

Phenols have the ability to neutralize free radicals, which are unstable molecules that can cause damage to cells and contribute to the development of chronic diseases such as cancer, heart disease, and neurodegenerative disorders. Some common examples of phenolic compounds include gallic acid, caffeic acid, ferulic acid, and ellagic acid, among many others.

Phenols can also have various pharmacological activities, including anti-inflammatory, antimicrobial, and analgesic effects. However, some phenolic compounds can also be toxic or irritating to the body in high concentrations, so their use as therapeutic agents must be carefully monitored and controlled.

"Chromans" are a class of organic compounds that contain a benzene fused to a five-membered saturated carbon ring containing one oxygen atom. This particular ring structure is also known as a chromane. Chromans have various applications in the field of medicinal chemistry and pharmacology, with some derivatives exhibiting biological activities such as antioxidant, anti-inflammatory, and cardiovascular protective effects. Some well-known chroman derivatives include vitamin E (tocopherols and tocotrienols) and several synthetic drugs like chromanol, a calcium channel blocker used in the treatment of hypertension and angina pectoris.

According to one study of nine common phytoestrogens in a Western diet, foods with the highest relative phytoestrogen content ... Phytoestrogens were first observed in 1926, but it was unknown if they could have any effect in human or animal metabolism. In ... Phytoestrogens are not essential nutrients because their absence from the diet does not cause a disease, nor are they known to ... Phytoestrogen content varies in different foods, and may vary significantly within the same group of foods (e.g. soy beverages ...
Kuhnle, G. G.; Dell'Aquila, C; Aspinall, S. M.; Runswick, S. A.; Mulligan, A. A.; Bingham, S. A. (2008). "Phytoestrogen content ... many of which act as phytoestrogens in mammals. Isoflavones are produced almost exclusively by the members of the bean family, ... "Evaluation of the Estrogenic Effects of Legume Extracts Containing Phytoestrogens". Journal of Agricultural and Food Chemistry ... Fabaceae (Leguminosae). Although isoflavones and closely related phytoestrogens are sold as dietary supplements, there is ...
... is a phytoestrogen, mimicking the biological activity of estrogens. Phytoestrogens are able to pass through cell ... Coumestrol and other phytoestrogens have been shown to have an effect on sexual behavior in rats by antagonizing the action of ... Coumestrol and other phytoestrogens are sometimes used as a substitute for hormone therapy in the treatment of menopausal ... Coumestrol and other phytoestrogens have also been investigated as a possible substitute for hormone therapy and chemotherapy ...
Some hair shampoos on the market include estrogens and placental extracts; others contain phytoestrogens. In 1998, there were ... Plant products with estrogenic activity are called phytoestrogens (e.g., coumestrol, daidzein, genistein, miroestrol). Those ...
Soy contains the phytoestrogen coumestans, also are found in beans and split-peas, with the best sources being alfalfa, clover ... March 2000). "Phytoestrogens and Prostate Disease". The Journal of Nutrition. 130 (3): 658S-59S. doi:10.1093/jn/130.3.658S. ... Soybeans and processed soy foods are among the richest foods in total phytoestrogens (wet basis per 100 g), which are present ... Some reviews have expressed the opinion that more research is needed to determine what effect the phytoestrogens in soybeans ...
In the plant, the phytoestrogens are involved in the defense system against fungi. Phytoestrogens can do two different things ... One such group of metabolites is phytoestrogens, found in nuts, oilseeds, soy, and other foods. Phytoestrogens are chemicals ... "Phytoestrogens and Breast Cancer." Cornell University. Cornell University, 31/03/2010. Web. 1 Apr 2011. . Richard C. Leegood, ... "Phytoestrogens and Breast Cancer." Cornell University. Cornell University, 31/03/2010. Web. 1 Apr 2011. . Warren, Barbour S., ...
... s, including coumestrol, a phytoestrogen, are found in a variety of plants. Food sources high in coumestans include ... Barbour S. Warren; Carol Devine (July 2001). "Phytoestrogens and Breast Cancer". Program on Breast Cancer and Environmental ... "Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta". Endocrinology. 139 (10): 4252-4263. doi: ...
Isoflavones, which are structurally related to 17β-estradiol, are classified as phytoestrogens. A risk assessment by the ... Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment (2003). "Phytoestrogens and Health" (PDF). " ...
Park, D; Huang, T; Frishman, WH (2005). "Phytoestrogens as cardioprotective agents". Cardiology in Review. 13 (1): 13-7. doi: ...
"Phytoestrogens and Health" (PDF). "SETE , Committee on Toxicity". cot.food.gov.uk. Retrieved 8 May 2022. "No. 56237". The ... It has a number of working groups that publish reports, e.g. previously on Phytoestrogens. It also works with other Scientific ...
"Natural Estrogens". Phytoestrogen Liang, K; Yang L; Xiao Z; Huang J (January 2009). "A bipartite recombinant yeast system for ... Nonsteroidal estrogens include xenoestrogens, phytoestrogens and mycoestrogens. They are very useful in neurodegenerative ... especially the contraceptives.Phytoestrogens are plant derived estrogens and have similar structures with 17beta-estradiol thus ... Phytoestrogens); 3) Fungi Estrogens (Mycoestrogens) and 4) Synthetic Estrogens (xenoestrogens). Xenoestrogens contain a large ...
... s are the principal source of dietary phytoestrogens in typical Western diets, even though most research on phytoestrogen ... The name derives from the Latin word for "wood". Lignans are precursors to phytoestrogens. They may play a role as antifeedants ...
Soy, flax, and other plant-based foods that contain phytoestrogens are also beneficial because they can inhibit some pituitary ... Falcon M. "Estrogens, Testosterone & Phytoestrogens". maxmuscle.com. Archived from the original on October 25, 2006. Shippen E ... though more recent studies have shown that soy actually contains phytoestrogens which compete with estrogens in the male body ...
Plants such as Kacip Fatimah have been found to contain phytoestrogens that could alleviate some symptoms of menopause. ... Patisaul, Heather B.; Jefferson, Wendy (2010-10-01). "The pros and cons of phytoestrogens". Frontiers in Neuroendocrinology. 31 ... Phytoestrogens are plant derived compounds found in a wide variety of foods. Several health benefits including a lowered risk ... of osteoporosis, heart disease, breast cancer, and menopausal symptoms are frequently attributed to phytoestrogens but many are ...
Mueller SO, Simon S, Chae K, Metzler M, Korach KS (April 2004). "Phytoestrogens and their human metabolites show distinct ... Patisaul, HB; Jefferson, W (October 2010). "The pros and cons of phytoestrogens". Front Neuroendocrinol. 31 (4): 400-419. doi: ... Teas, J.; Hurley, TG (August 2009). "Dietary seaweed modifies estrogen and phytoestrogen metabolism in healthy postmenopausal ... plasma concentration and urinary excretion for accurate estimation of phytoestrogen intake". Journal of Epidemiology. 10 (2): ...
Lampe JW (2003). "Isoflavonoid and lignan phytoestrogens as dietary biomarkers". J Nutr. 133 (Suppl 3): 956S-964S. doi:10.1093/ ... "Urinary excretion of lignans and isoflavonoid phytoestrogens in Japanese men and women consuming a traditional Japanese Diet". ...
Thompson, L. U.; Boucher, B. A.; Liu, Z; Cotterchio, M; Kreiger, N (2006). "Phytoestrogen content of foods consumed in Canada, ... Lampe JW (2003). "Isoflavonoid and lignan phytoestrogens as dietary biomarkers". J Nutr. 133 (Suppl 3): 956S-964S. doi:10.1093/ ...
The term is based on the presence of the phytoestrogen isoflavone in soybeans, which has led some to claim that soy products ... Rietjens I. M. C. M.; Louisse J.; Beekmann K. (June 2017). "The potential health effects of dietary phytoestrogens". British ... Soy products contain high amounts of phytoestrogens. As they are structurally similar to estradiol (the major female sex ... While there is some evidence that phytoestrogens may affect male fertility, "further investigation is needed before a firm ...
It is described as an angiogenesis inhibitor and a phytoestrogen. It was first isolated in 1899 from the dyer's broom, Genista ... It has also been shown that genistein makes some cells more sensitive to radio-therapy.; although, timing of phytoestrogen use ... de Lemos, Mário L (2001). "Effects of Soy Phytoestrogens Genistein and Daidzein on Breast Cancer Growth". The Annals of ... Dang, Zhi Chao; Lowik, Clemens (2005). "Dose-dependent effects of phytoestrogens on bone". Trends in Endocrinology and ...
They may be either of natural origin, such as phytoestrogens, which are derived from plants, or of synthetic origin. These ... It has also been claimed that certain xenoestrogens, most commonly phytoestrogens and mycoestrogens can have beneficial health ... Naturally occurring xenoestrogens include phytoestrogens (estrogen-like compounds from plants) and mycoestrogens (estrogen-like ... "The potential health effects of dietary phytoestrogens". British Journal of Pharmacology. 174 (11): 1263-1280. doi:10.1111/bph. ...
Angelica, containing phytoestrogens, has long been used for gynaecological disorders. Polyphenols include phytoestrogens (top ... They include hormone-mimicking phytoestrogens and astringent tannins. Plants containing phytoestrogens have been administered ... "Molecular aspects of phytoestrogen selective binding at estrogen receptors". Journal of Pharmaceutical Sciences. 96 (8): 1879- ...
However, formonetin-a phytoestrogen compound (isoflavone)-could only be detected in methanolic extracts and was not found in ... just another phytoestrogen?". Trends in Endocrinology and Metabolism. 16 (5): 214-221. doi:10.1016/j.tem.2005.05.002. PMID ...
Tice JA, Ettinger B, Ensrud K, Wallace R, Blackwell T, Cummings SR (July 2003). "Phytoestrogen supplements for the treatment of ... It is enriched with isoflavone phytoestrogens such as formononetin, biochanin A, daidzein, and genistein, and is proposed to ... Ososki AL, Kennelly EJ (September 2003). "Phytoestrogens: a review of the present state of research". Phytother Res. 17 (8): ... Phytoestrogens, Selective estrogen receptor modulators, All stub articles, Genito-urinary system drug stubs). ...
Natural xenoestrogens include phytoestrogens which are plant-derived xenoestrogens. Because the primary route of exposure to ... "Phytochemical mimicry of reproductive hormones and modulation of herbivore fertility by phytoestrogens". Environmental Health ... Environmental xenobiotic Epidemiology and etiology of breast cancer List of breast carcinogenic substances Phytoestrogens ...
In addition, many of these compounds are also phytoestrogens. Examples include the following: Lion's Mane mushrooms Alizarin,[ ...
Other forms of endocrine disruptors are phytoestrogens (plant hormones). Xenoestrogens are a type of xenohormone that imitates ... as well as naturally occurring phytoestrogens such as genistein and mycoestrogens such as zearalenone. The molting in ...
1 March 1995). "Soybean phytoestrogen intake and cancer risk". Journal of Nutrition. 125 (3 Suppl): 757S-770S. ISSN 0022-3166. ...
Sometimes it is called a phytoestrogen. For the structure-activity relationships of zearalenone and its analogues, see Hurd and ... it also has been labeled a phytoestrogen, a mycoestrogen, and a growth promotant. Citrinin: Citrinin was first isolated from ...
Coldham, N.G; Sauer, M.J (2001). "Identification, quantitation and biological activity of phytoestrogens in a dietary ... specifically known as phytoestrogens in plants and mycoestrogens in fungi). Commonly used ingredients include:: 1330 : 1345 ...
Most studies of phytoestrogens in soy have identified the isoflavones genistein and daidzein as its principal phytoestrogenic ... Adams, N. R. (1995). "Detection of the effects of phytoestrogens on sheep and cattle". J. Animal Sci. 73: 1509-1515. doi: ... Reinli, K.; Block, G. (1996). "Phytoestrogen content of foods-a compendium of literature values". Nutrition and Cancer. 26: 123 ... Although reproductive physiology of sheep is particularly sensitive to phytoestrogens, soybean meal supplementation of ewe ...
According to one study of nine common phytoestrogens in a Western diet, foods with the highest relative phytoestrogen content ... Phytoestrogens were first observed in 1926, but it was unknown if they could have any effect in human or animal metabolism. In ... Phytoestrogens are not essential nutrients because their absence from the diet does not cause a disease, nor are they known to ... Phytoestrogen content varies in different foods, and may vary significantly within the same group of foods (e.g. soy beverages ...
Posts about phytoestrogens written by What Doctors Dont Tell You ... NEWS:PHYTOESTROGENS PROTECT AGAINST BREAST CANCER. What Doctors ... Of the several types of phytoestrogens, isoflavones (found mainly in legumes, particularly soya beans), lignans (found in ...
Phytoestrogens - Urine (PHYTO_D) Data File: PHYTO_D.xpt First Published: August 2011. Last Revised: NA ... Urinary Phytoestrogens: Limit of Detection in nanogram/milliliter. Analyte. SAS Variable. LOD (ng/mL). ... Phytoestrogens are then separated from other urine components by reversed phase HPLC, detected by APPI-MS/MS, and quantified by ... 2004). Phytoestrogens are capable of estrogen-receptor binding (Cornwell et al., 2004) and may also influence other biologic ...
Phytoestrogens - Urine (PHYTO_F) Data File: PHYTO_F.xpt First Published: January 2013. Last Revised: NA ... Urinary Phytoestrogens: Limit of Detection in nanogram/milliliter. Analyte. SAS Variable. LOD (ng/mL). ... Phytoestrogens are then separated from other urine components by reversed phase HPLC, detected by APPI-MS/MS, and quantified by ... 2004). Phytoestrogens are capable of estrogen-receptor binding (Cornwell et al., 2004) and may also influence other biologic ...
3. Phytoestrogens. Phytoestrogens are chemical compounds found naturally in plants, in which they act as fungicides (Sukumuran ... 5. Phytoestrogen metabolism. Most phytoestrogens are consumed as glycosylated precursors, which is why they need to be ... 4. Structure, classification and mechanisms of action of phytoestrogens. Phytoestrogens are non-steroidal compounds with a ... The levels of phytoestrogens will depend on the diet, since variations of 14.3 nM/L to 378 nM/L are reported. During lactation ...
Phytoestrogens (plant estrogens). Phytoestrogens are estrogens that occur in some plants. Foods containing phytoestrogens ... The risks of long-term use of non-food phytoestrogens, like phytoestrogen supplements or red clover pills, however, are not ... A recent review of the pros and cons of phytoestrogens concluded that the issue of whether phytoestrogens are beneficial or ... For instance, the bone-sparing benefits of phytoestrogen are mediated by phytoestrogen conversion to equol, which approximately ...
Why is it good to eat food rich in phytoestrogens during menopause? Main food containing phytoestrogens ... Properties of phytoestrogens. Tempeh is a soy product that contains a great amount of phytoestrogens. The ingestion of these ... Types of phytoestrogens. * Soy isoflavones or isoflavonoids: they are the type of phytoestrogens that are most consumed today, ... Benefits of plant foods rich in phytoestrogens. What are phytoestrogens and what are they for?. The chemical formula of a human ...
Gut Microbiota and Phytoestrogen-Associated Infertility in Southern White Rhinoceros. April 9, 2019. ... The researchers show that reproductive outcomes may be driven by the gut microbiotas transformation of dietary phytoestrogens ... the study also demonstrates species differences in estrogen receptor sensitivity to phytoestrogen metabolites produced. The ... the team of researchers provided insight into the relationship between microbially mediated phytoestrogen metabolism and ...
The promise of phytoestrogens. Behram S Anklesaria. Chairman, Indian College of Obstetrics and Gynecology, Past President, ...
Phytoestrogen-Based Hormonal Replacement Therapy Could Benefit Women Suffering Late-Onset Asthma.. Oct 30, 2023 ... Therefore, the present review proposes phytoestrogens as a promising HRT that might provide these females with relief for both ... Besides their well-recognized anti-inflammatory and antioxidant capacities, phytoestrogens activate estrogen receptors and ...
It was the aim of this study to examine the relationship between the serum PSA level and urine phytoestrogen concentration in ... It was the aim of this study to examine the relationship between the serum PSA level and urine phytoestrogen concentration in ... Association of urinary phytoestrogen concentrations with serum concentrations of prostate-specific antigen in the National ... Some clinical trials have shown that high phytoestrogen intake may decrease serum concentrations of prostate-specific antigen ( ...
A phytoestrogen, genistein, reversed 17 β-estradiol or bisphenol A-induced cell growth via downregulation of the cell cycle ... A phytoestrogen, genistein, reversed 17 [beta]-estradiol or bisphenol A-induced cell growth via downregulation of the cell ... A phytoestrogen, genistein, reversed 17 [beta]-estradiol or bisphenol A-induced cell growth via downregulation of the cell ... In this study, we examined the effect of a phytoestrogen, genistein, on the cell growth of BG-1 ovarian cancer cells expressing ...
...  Metadata Field. Value. Language ... Soy phytoestrogens have been shown to reduce lipid accumulation in the liver and increase bone mineral content and bone density ... The Estrogenic Effects of the Soy Phytoestrogen Genistein on the Liver and Bone of Chickens. en_US. ... Research evidence suggests that soy phytoestrogens may have a protective effect against liver lipid accumulation induced by ...
Phytoestrogens are chemicals produced by plants that act like estrogens. Flax seeds have the highest content. Soy beans and ... Phytoestrogens are important in the diet to prevent some forms of prostate cancer. ... Retrieved from "https://bots.SNPedia.com/index.php?title=Phytoestrogens&oldid=42526" ...
Natural remedies for period pain ... are you ready for this? Today, we going to discuss some safe and natural ways to deal with that annoying relative that your "monthly visitor" often brings along with her. You know who Im talking about, dont you - Menstrual Cramps. Aint she a bitch! Were … [Read more...] ...
This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.. ...
Getting Phytoestrogens Through Your Skin. There are now lotions and creams available that can deliver phytoestrogen isoflavones ... brain fog breast cancer estrogen herbs hormones hot flash isoflavones menopause night sweats phytoestrogens risk sleep soy ... To sum up, remember, soy contains a plant-based or phytoestrogen that is safe to have at all times of life, including menopause ... There have been studies reported by the NIH that support phytoestrogens as effective in the treatment of aging skin by ...
Soy isoflavones contains natural phytoestrogens- natural plant oestrogens. ... which are natural phytoestrogens, literally oestrogens from plants, that are similar in structure to the human hormone ...
The prostate, a small gland responsible for the production of seminal fluid in men, deserves more attention when it comes to nutritional care. The foods we eat can have a significant impact on prostate health… ...
Phytoestrogens. All soybean proteins and foods currently available for human consumption contain significant amounts of the ... The isoflavones have structural homology to steroidal estrogens; therefore, they are considered to be phytoestrogens, but ... Without conclusive findings in humans, ESPGHAN recommends reducing the content of phytoestrogens in soy protein formulas ... the concerns about the adverse role of phytoestrogens in the first months of life are exclusively theoretical. At this time, ...
Phytoestrogen-rich foods help increase estrogen levels, particularly in postmenopausal women prone to estrogen deficiency. But ... What Are Phytoestrogens?. Phytoestrogens are plant foods that resemble the estrogen compounds in the body and are capable of ... There are certain phytoestrogen-rich foods that act in a similar manner as the estrogen that we naturally create in our bodies. ... The phytoestrogen content in this fruit can prove effective in breast cancer survival in women who have gone through menopause. ...
Isoflavones and lignans (so-called phytoestrogens). *Breast Cancer Research Centers - Breast cancer and the environment ...
What are phytoestrogens?. Phytoestrogens are plant-derived substances that can show oestrogen-like activity when ingested. ... Can phytoestrogens help the psychological symptoms of menopause?. Less research has explored whether phytoestrogens improve ... Some research suggests phytoestrogens may reduce the risk of dementia, but there are no conclusive findings regarding their ... If you do wish to see if they might work for you, start by including more phytoestrogen-rich foods in your diet. Examples ...
Phytoestrogens- a natural way to combat menopause , Contact in2Great TODAY for more information on this and more! ... What are phytoestrogens?. Phytoestrogens are plant compounds found in a wide variety of foods. However, most people believe ... While phytoestrogens are found in all types of food, there are is one specific phytoestrogen that has been found to be ... While there are many different types of phytoestrogens, the specific phytoestrogens that have been found to be most helpful for ...
Elixir10 Phytoestrogen Booster is a mix of beneficial botanical extracts and antioxidants, ...
doTERRA Women Phytoestrogen Essential Complex is a blend of standardized plant phytoestrogens that support hormone balance ...
This diet contains not any Soybean and alfalfa product resulting is very low concentration of phytoestrogen genistein,daidzein ... Datasheet 3309 Low in phytoestrogens vitamin-fortified, suitable for autoclaving, with anti-cacking coating ... 3309 Low in phytoestrogens vitamin-fortified, suitable for autoclaving, with anti-cacking coating ...
The phytoestrogens found in soy are known as isoflavones, and they act like estrogen in the body. They are believed to be ... Tagged Under: disease causes, Endocrine disruptors, GMO, hormones, ingredients, isoflavones, phytoestrogens, soy, soy products ... They even found phytoestrogens in some surprising places, such as beef meatballs and chicken nuggets. ... and goitrogens in addition to phytoestrogens. Phytates can reduce your bodys assimilation of important nutrients like zinc, ...
Phytoestrogen concentrations in serum and spot urine as biomarkers for dietary phytoestrogen intake and their relation to ... Urinary phytoestrogens and postmenopausal breast most cancers danger. Soybean phytoestrogens intake and cancer threat. ... Phytoestrogens Are Ancient Naturally Occurring Substances * Six Easy Methods The Professionals Use To Advertise Pueraria ... Tags: Chinese food intake Japanese phytoestrogens reference relation threat weight loss program ...
Whats the relationship between Phytoestrogens and breast cancer? Believe it or not, there is one, but its not what you might ... Phytoestrogen-rich foods. Now, lets be clear, gang. Were in no way saying that eating phytoestrogens will prevent, cure, or ... So what have Phytoestrogens got to do with any of this? Well, as part of the treatment for those cancers, patients are often ... Phytoestrogens: Do I eat them or not?. That very much depends on your diagnosis. If youre hormone-receptor positive cancer- ...
  • In the human diet, phytoestrogens are not the only source of exogenous estrogens. (wikipedia.org)
  • Phytoestrogens are plant-derived polyphenolic compounds, such as isoflavones and lignans that are structurally similar to endogenous estrogens (Cornwell, et al. (cdc.gov)
  • Phytoestrogens are estrogens that occur in some plants. (nwhn.org)
  • They are characterized by having a chemical structure similar to that of estrogenic hormones, reason why they are known as phytoestrogens or plant estrogens. (botanical-online.com)
  • Research evidence suggests that soy phytoestrogens may have a protective effect against liver lipid accumulation induced by estrogens in mammals. (auburn.edu)
  • Phytoestrogens are chemicals produced by plants that act like estrogens. (snpedia.com)
  • Natural phytoestrogens, or dietary estrogens are one of the most efficient ways to help increase hormonal levels. (in2greatkc.com)
  • The most popular nutritional supplements for hot flushes are phytoestrogens (or plant estrogens). (pharmacyitk.com.au)
  • White and his fellow researchers speculate that soy's estrogen-like compounds (phytoestrogens) might compete with the body's natural estrogens for estrogen receptors in brain cells. (westonaprice.org)
  • Similarly inconclusive findings appeared in the case of cardiovascular health, where Rietjens and colleagues found that "the current evidence [for phytoestrogens] appears poor compared to that available for estrogens. (medpagetoday.com)
  • Health benefits attributed to a diet rich in phytoestrogens include relief from menopausal symptoms and lowered risk of osteoporosis, heart disease and breast cancer. (nwhn.org)
  • During menopause, when estrogen levels start to decrease, phytoestrogens can help to increase these levels naturally and reduce menopausal symptoms. (in2greatkc.com)
  • In the case of isoflavones, initial support came from epidemiological data showing women in Asian countries , consuming a traditional, phytoestrogen-rich diet (that is, one including tofu, miso and fermented or boiled soybeans), experienced fewer menopausal symptoms than women in Western countries. (pharmacyitk.com.au)
  • However, several factors may influence the effect of dietary phytoestrogens on menopausal symptoms. (pharmacyitk.com.au)
  • Circulating oestrogen levels (which drop considerably during menopause) and the duration of soy intake (longer-term intake being more favourable) may also influence the effect of dietary phytoestrogens on menopausal symptoms. (pharmacyitk.com.au)
  • Furthermore, phytoestrogens are used as a natural alternative to hormone replacement therapy and to reduce menopausal symptoms. (huji.ac.il)
  • Lignans have also been identified as phytoestrogens, although they are not flavonoids. (wikipedia.org)
  • They are an incredibly rich source of lignans, the substance that gives these seeds their phytoestrogen abilities. (wellnesswarrior.org)
  • Urinary excretion of lignans and isoflavone phytoestrogens in Japanese women and men consuming a conventional Japanese eating regimen. (perfect-curve.com)
  • The two major groups of phytoestrogens, isoflavones and lignans, are abundant in soy products and flax respectively, but are also present in a variety of other foods. (huji.ac.il)
  • In this paper, data on the complex mammary effects of phytoestrogens in epidemiological studies, in in vitro studies, as well as in in vivo studies on animal carcinogenesis are reviewed. (drlauda.at)
  • The estrogenic effects of phytoestrogens that penetrate the skin enable cosmetic manufacturers to determine which problem areas to focus on. (style-beauty.com)
  • This [study] implies that a definite conclusion on the health effects of phytoestrogens, positive or negative, cannot be made," the lead study author, Ivonne Rietjens, PhD , professor in toxicology at Wageningen University in The Netherlands, said in a statement. (medpagetoday.com)
  • Conversely, some of the more widely discussed harmful effects of phytoestrogens also remain unproven. (medpagetoday.com)
  • In addition to this, applied locally to the desired area, a product rich in phytoestrogens would have a beneficial effect on its shape and its tight appearance. (style-beauty.com)
  • rich in phytoestrogens, particularly isoflavones, which mimic the body's natural estrogen. (lilgenesis.com)
  • The aguaje fruit is rich in PHYTOESTROGENS water source, vitamins and minerals that enhance internal and external health of women's body skin and hair. (herbadiet.in)
  • This consumer health information provides a brief overview of the National Women's Health Network's perspective and some guidance on two types of alternative products promoted for women at menopause: phytoestrogens and herbs. (nwhn.org)
  • Traditionally plants with phytoestrogens have been used to replace the hormonal deficits that occur, for example, during menopause , and thus alleviate the symptoms produced as a result of hormonal depletion such as hot flashes. (botanical-online.com)
  • Therefore, the present review proposes phytoestrogens as a promising HRT that might provide these females with relief for both their menopause and asthma symptoms. (physiciansweekly.com)
  • While phytoestrogens are found in all types of food, there are is one specific phytoestrogen that has been found to be especially helpful for balancing hormones during menopause. (in2greatkc.com)
  • Phytoestrogens exert their effects primarily through binding to estrogen receptors (ER). (wikipedia.org)
  • Emerging evidence shows that some phytoestrogens bind to and transactivate peroxisome proliferator-activated receptors (PPARs). (wikipedia.org)
  • In addition, when acting on estrogen receptors, phytoestrogens behave differently from estrogen and more like Selective Estrogen Receptor Modulators (SERMs). (nwhn.org)
  • Besides their well-recognized anti-inflammatory and antioxidant capacities, phytoestrogens activate estrogen receptors and promote mild hormone-like responses that benefit postmenopausal women, particularly asthmatics, constituting therefore a very attractive potential therapy largely due to their low toxicity and scarce side effects. (physiciansweekly.com)
  • In this study, we examined the effect of a phytoestrogen, genistein, on the cell growth of BG-1 ovarian cancer cells expressing estrogen receptors (ERs) caused by E2 and BPA. (endocrine-abstracts.org)
  • The reason phytoestrogens are able to mimic estrogen so well is because they have very similar structures allowing it to bind to the body's own estrogen receptors. (in2greatkc.com)
  • 1997). Phytoestrogens may additionally act by pathways aside from the interplay with estrogen receptors. (perfect-curve.com)
  • while phytoestrogens have a pretty good ability to bind to estrogen receptors, they are not able to signal as well as estrogen. (healthtoempower.com)
  • Phytoestrogens look enough like estrogen to bind to estrogen receptors, but they do not look exactly like estrogen. (healthtoempower.com)
  • In their perspective, phytoestrogens would signal "fullness" to the estrogen receptors. (healthtoempower.com)
  • A phytoestrogen is a plant-derived xenoestrogen (see estrogen) not generated within the endocrine system, but consumed by eating plants or manufactured foods. (wikipedia.org)
  • The consumption of diets high in phytoestrogen-rich foods has been associated with lower rates of hormone-dependent cancers (Peeters et al. (cdc.gov)
  • Phytoestrogens are present in some plants and foods. (botanical-online.com)
  • The following list contains foods with many phytoestrogens in order from highest to lowest. (botanical-online.com)
  • Here is a list of foods that are high in phytoestrogens. (snpedia.com)
  • There are certain phytoestrogen-rich foods that act in a similar manner as the estrogen that we naturally create in our bodies. (wellnesswarrior.org)
  • Phytoestrogens are plant compounds found in a wide variety of foods. (in2greatkc.com)
  • Phytoestrogens can be consumed in foods like tofu or soy milk. (pharmacyitk.com.au)
  • So what foods contain phytoestrogens? (healthtoempower.com)
  • This list documents the phytoestrogen content in some common foods. (healthtoempower.com)
  • Some unexpected foods that contain phytoestrogens include garlic, hops and olive oil. (healthtoempower.com)
  • By far, the foods that contain the most phytoestrogens are soy and flax. (healthtoempower.com)
  • Foods lower in phytoestrogen content such as chick peas or wheat have a very minimal phytoestrogenic impact. (healthtoempower.com)
  • UFC-Que Choisir has raised concerns over the safety of soy-based products after elevated levels of phytoestrogens were found in various drinks, desserts, sauces, and prepared foods. (foodnavigator.com)
  • The amount of phytoestrogens that are in a day's worth of soy infant formula equals 5 birth control pills," says Mike Fitzpatrick, a New Zealand toxicologist. (westonaprice.org)
  • Genistein, an isoflavone, is one of phytoestrogens that are plant-derived, naturally occurring, and dietary xenoestrogens and influences multiple biochemical functions. (endocrine-abstracts.org)
  • Taken together from these results, we may suggest an anticancer effect of genistein, a dietary phytoestrogen, on the estrogen-dependant cancers like ovarian cancer prompted by E2 or BPA. (endocrine-abstracts.org)
  • Research has suggested that the primary soy phytoestrogen, genistein, may help alleviate osteoporosis in women by increasing bone density through its estrogenic action. (auburn.edu)
  • This diet contains not any Soybean and alfalfa product resulting is very low concentration of phytoestrogen genistein,daidzein and coumestrol which make this diet suitable for studies on the effects of oestrogens and similar substance. (kliba-nafag.com)
  • Phytoestrogen concentrations in serum and spot urine as biomarkers for dietary phytoestrogen intake and their relation to breast cancer threat in European potential investigation of cancer and nutrition-Norfolk. (perfect-curve.com)
  • So, what's the real deal with Phytoestrogens and breast cancer? (hormona.io)
  • And it's just possible that, having eaten those phytoestrogens regularly over the course of your life may offer some small protection against developing breast cancer. (hormona.io)
  • Phytoestrogens are natural constituents of our diets that have been suggested to protect against hormone-dependent breast cancer. (drlauda.at)
  • Hence the inhibition of sulphotransferases by dietary phytoestrogens may have complex effects upon human susceptibility to breast cancer. (drlauda.at)
  • The potential benefits and risks of phytoestrogens are analyzed, and the prescription of phytoestrogens to postmenopausal women after breast cancer and the coprescription with the anti-estrogen tamoxifen are discussed. (drlauda.at)
  • Creams with phytoestrogens can help alleviate some of these symptoms, offering relief alongside lifestyle adjustments. (lilgenesis.com)
  • The similarities, at molecular level, of an estrogen and a phytoestrogen allow them to mildly mimic and sometimes act as an antagonist of estrogen. (wikipedia.org)
  • Phytoestrogens have been studied for years due to its unique ability to mimic the body's own estrogen. (in2greatkc.com)
  • This is why Phytoestrogens are becoming increasingly popular among women looking for natural ways to increase estrogen levels, particularly postmenopausal women prone to estrogen deficiency. (wellnesswarrior.org)
  • A Cochrane review synthesised study results and failed to find conclusive evidence phytoestrogens, in food or supplement form, reduced the frequency or severity of hot flushes or night sweats in perimenopausal or postmenopausal women. (pharmacyitk.com.au)
  • Urinary phytoestrogens and postmenopausal breast most cancers danger . (perfect-curve.com)
  • Phytoestrogens mainly belong to a large group of substituted natural phenolic compounds: the coumestans, prenylflavonoids and isoflavones are three of the most active in estrogenic effects in this class. (wikipedia.org)
  • Phytoestrogens have been shown to induce both estrogenic and anti-estrogenic effects but their biological relevance and potency have not been well characterized. (huji.ac.il)
  • Phytoestrogen-Based Hormonal Replacement Therapy Could Benefit Women Suffering Late-Onset Asthma. (physiciansweekly.com)
  • Outcomes of chronic feeding research in pregnant animals suggest that high doses of phytoestrogens alter the fetal hormonal surroundings (Cornwell et al. (perfect-curve.com)
  • It is a plant source of phytoestrogen and acts like estrogen in the body. (wellnesswarrior.org)
  • Soy contains a certain kind of molecule called a "phytoestrogen" that acts like estrogen in the body.Health professionals disagree strongly about whether phytoestrogens are healthy for women to eat. (healthtoempower.com)
  • Although mycoestrogens are rarely taken into account in discussions about phytoestrogens, these are the compounds that initially generated the interest on the topic. (wikipedia.org)
  • Biomeasures of phytoestrogens are necessary to establish reference ranges for these compounds and to evaluate their potential effects on human health. (cdc.gov)
  • For the same reasons that we question the use of hormone therapy, the Network approaches herbs and phytoestrogens by looking for reliable information on effectiveness and safety. (nwhn.org)
  • The chemical formula of a human estrogenic hormone (estradiol) and a phytoestrogen (equol) is observed in the image. (botanical-online.com)
  • In the body phytoestrogens have an estrogenic effect, which helps to balance hormone levels out. (in2greatkc.com)
  • And it's that, for the most part, eating a phytoestrogen-rich diet isn't always a terrible idea if you've been diagnosed with a hormone-sensitive tumor. (hormona.io)
  • Do dietary phytoestrogens influence susceptibility to hormone-dependent cancer by disrupting the metabolism of endogenous oestrogens? (drlauda.at)
  • These are so high in phytoestrogens that they can impact pretty much everybody, no matter their hormone health. (healthtoempower.com)
  • In all cases, with hormone balance issues, as well as people who regularly consume vegetable oils, nuts and soy, would do well to consider how potent their phytoestrogen intake may be . (healthtoempower.com)
  • the study also demonstrates species differences in estrogen receptor sensitivity to phytoestrogen metabolites produced. (asm.org)
  • Finding a measurable quantity of one or more phytoestrogen metabolites in urine doesn't suggest that the levels of the metabolites or the guardian phytoestrogen trigger an hostile well being effect. (perfect-curve.com)
  • Biomonitoring studies on the levels of phytoestrogen metabolites provide physicians and public well being officials with reference values in order that they can decide whether or not folks have been uncovered to greater ranges of phytoestrogens than those present in the overall population. (perfect-curve.com)
  • On the other hand, phytoestrogens are also considered endocrine disruptors, indicating that they have the potential to cause adverse health effects such as infertility and increased risks on cancer of estrogen-sensitive organs. (medpagetoday.com)
  • While there are many different types of phytoestrogens, the specific phytoestrogens that have been found to be most helpful for balancing hormones is isoflavones, which can be found in soy products and flax seeds. (in2greatkc.com)
  • The phytoestrogens found in soy are known as isoflavones, and they act like estrogen in the body. (cancer.news)
  • The study, published in the British Journal of Pharmacology , focused specifically on phytoestrogens, plant-based estrogen alternatives commonly found in soy, soy products, and other legumes. (medpagetoday.com)
  • Rietjens and colleagues found conflicting and inconclusive studies regarding whether phytoestrogens can reduce the frequency or severity of hot flashes. (medpagetoday.com)
  • Phytoestrogens have been shown to relieve hot flashes, prevent osteoporosis in women, provide menstrual relief, and acne treatment. (in2greatkc.com)
  • This specific phytoestrogen is found abundantly in soy products and flax seeds. (in2greatkc.com)
  • Some clinical trials have shown that high phytoestrogen intake may decrease serum concentrations of prostate-specific antigen (PSA), and phytoestrogens may also lower prostate cancer risk. (uzh.ch)
  • The linear regression analyses showed no clear association between creatinine-standardized urinary phytoestrogen concentrations and serum total or free PSA levels or PSA ratio. (uzh.ch)
  • The isoflavones are a group of phytoestrogens that are present in high concentrations in soy. (drlauda.at)
  • Overall, evidence regarding the benefit of phytoestrogens for hot flushes is fairly mixed. (pharmacyitk.com.au)
  • Human urine samples are processed using enzymatic deconjugation of the glucuronidated phytoestrogens followed by size-exclusion filtration. (cdc.gov)
  • Phytoestrogens are then separated from other urine components by reversed phase HPLC, detected by APPI-MS/MS, and quantified by isotope dilution. (cdc.gov)
  • This selective method allows for rapid detection of phytoestrogens in human urine with limits of detection in the low parts per billion (ng/mL) range. (cdc.gov)
  • It was the aim of this study to examine the relationship between the serum PSA level and urine phytoestrogen concentration in generally healthy U.S. men. (uzh.ch)
  • Phytoestrogens exert their beneficial effects through several mechanisms that slow cell growth and prevent inflammation. (nwhn.org)
  • Phytoestrogens are plant-derived substances that can show oestrogen-like activity when ingested. (pharmacyitk.com.au)
  • But Phytoestrogens, or plant-derived Estrogen, have been hailed as both cause and cure. (hormona.io)
  • That complexity is perhaps best encapsulated in the research review regarding plant-based estrogen's effects on menopausal women -- one of the most widely touted and discussed of phytoestrogens' many potential applications. (medpagetoday.com)
  • They are beneficial both as a phytoestrogen and also as a way to reduce cholesterol in the blood. (wellnesswarrior.org)
  • Although there has not been enough research conducted into the effects of wheat bran's phytoestrogen levels on the body, it is a rich source of phytoestrogens and could prove beneficial. (wellnesswarrior.org)
  • It may be that the question of whether phytoestrogens are beneficial or harmful has different answers dependent on individuals' age, health status, and even the presence or absence of specific gut bacteria. (medpagetoday.com)
  • Consequently, the question of whether phytoestrogens are beneficial or harmful to human health remains of importance. (medpagetoday.com)
  • In children, consumption of soy-based formulas and soy milk can lead to high levels of exposure to phytoestrogens with only limited data available concerning potential benefits or adverse effects. (huji.ac.il)
  • There are two variants of the estrogen receptor, alpha (ER-α) and beta (ER-β) and many phytoestrogens display somewhat higher affinity for ER-β compared to ER-α. (wikipedia.org)
  • 2004). Phytoestrogens are capable of estrogen-receptor binding (Cornwell et al. (cdc.gov)
  • Using a combined approach of parallel sequencing, mass spectrometry, and estrogen receptor activation assays, the team of researchers provided insight into the relationship between microbially mediated phytoestrogen metabolism and fertility that is novel for any vertebrate species. (asm.org)
  • Comparability of isoflavones among dietary intake, plasma focus and urinary excretion for correct estimation of phytoestrogen intake . (perfect-curve.com)
  • The consumption of plants with unusual content of phytoestrogens, under drought conditions, has been shown to decrease fertility in quail. (wikipedia.org)
  • In recent animal studies at Brigham Young University's Neuroscience Center, researchers found that consumption of phytoestrogens via a soy diet for a relatively short interval can significantly elevate phytoestrogen levels in the brain and decrease brain calcium-binding proteins. (westonaprice.org)
  • Select a food supplement with a high phytoestrogen content. (phytosoya.com)
  • Fitzpatrick and other scientists believe that infant exposure to high amounts of phytoestrogens is associated with early puberty in girls and retarded physical maturation in boys. (westonaprice.org)
  • Unfortunately, consuming high quantities of phytoestrogens often interferes with this otherwise healthfully functioning feedback loop. (healthtoempower.com)
  • On the other end of the spectrum, many doctors argue that women with high estrogen levels should supplement with phytoestrogens. (healthtoempower.com)
  • However, phytoestrogens can also inhibit enzymes that are involved in the generation and removal of endogenous steroid hormones. (drlauda.at)
  • Estrogen and phytoestrogen are the so-called female hormones. (style-beauty.com)
  • These phytoestrogens can interfere with the mammalian hormones involved in reproduction and growth-a strategy to reduce the number and size of predators. (westonaprice.org)
  • Many studies of garlic as a phytoestrogen in animals have shown that it boosts the levels of estrogen circulating in the bloodstream. (wellnesswarrior.org)
  • In addition to the fact that much of the soy grown in the U.S. is genetically modified, researchers have recently warned that soy-based products contain "alarming" levels of phytoestrogens . (cancer.news)
  • Phytoestrogens have been investigated at the epidemiological, clinical and molecular levels to determine their potential health benefits. (huji.ac.il)
  • To many doctors, this means that women with low estrogen levels should eat phytoestrogens. (healthtoempower.com)
  • dōTERRA Ženy Phytoestrogen Essential Complex je zmes štandardizovaných rastlinných fytoestrogénov, ktoré podporujú hormonálnu rovnováhu jemne a prirodzene. (terralife.sk)
  • u003eGNC Women´s Phytoestrogen. (com.gt)
  • they are the type of phytoestrogens that are most consumed today, due to the enormous richness in these components contained in soy and its derivatives, such as tofu, tempeh, miso, etc. (botanical-online.com)
  • In a 1999 letter to the FDA (and on the ABC News program 20/20), the two toxicologists expressed their opposition to the agency's health claims for soy, saying the Honolulu study "provides evidence that soy (tofu) phytoestrogens cause vascular dementia. (westonaprice.org)
  • The remaining 12 studies, testing phytoestrogen doses of up to 200 mg/day, showed no effects of soy isoflavones on bone mineral density or markers of bone formation or resorption. (medpagetoday.com)
  • Estro Tincture Natural phytoestrogen replacement support is the perfect all natural female support supplement with the benefits of black and blue cohosh. (experience-essential-oils.com)
  • In the 1940s and early 1950s, it was noticed that some pastures of subterranean clover and red clover (phytoestrogen-rich plants) had adverse effects on the fecundity of grazing sheep. (wikipedia.org)
  • 2005). Numerous studies of both dietary soy or phytoestrogens and health outcomes have demonstrated inconsistent or inconclusive results. (perfect-curve.com)
  • That's why products like Nano BB Shaper have over 20% phytoestrogens in their formula. (style-beauty.com)
  • Soy phytoestrogens have been shown to reduce lipid accumulation in the liver and increase bone mineral content and bone density in humans. (auburn.edu)