Paragonimus
Lung Diseases, Parasitic
Paragonimus westermani
Shellfish
Anthelmintics
Laos
Pleural Effusion
Brachyura
Missouri
Food Parasitology
Central Nervous System Helminthiasis
Astacoidea
Antigens, Helminth
Metacercariae
Fasciola
Clonorchiasis
Cameroon
Trematoda
Changes of splenocyte IFN-gamma mRNA synthesis in rats infected with Paragonimus westermani. (1/95)
Changes in the expression level of splenocyte IFN-gamma mRNA of Sprague-Dawley (SD) rats infected with Paragonimus westermani were analyzed by competitive reverse transcription-polymerase chain reaction (RT-PCR) followed by southern blot. The template RNA was extracted from the splenocytes of rats infected with 20 metacercariae of P. westermani. The products of competitive RT-PCR were subjected to southern blot and enhanced chemiluminescence (ECL), and analyzed with a densitometer. In comparison with that of uninfected control rat splenocytes (value of 1), the levels of mRNA expression of IFN-gamma had changed to 0.747 at 1 week post infection (PI), 0.00175 at 2 week PI, 0.0217 at 3 week PI, 0.194 at 4 week PI and then to 0.537 at 5 week PI. The level at 7 week PI had returned to 1.25, comparable with that of uninfected rats. These results show that, when infected with P. westermani, the levels of IFN-gamma mRNA of SD rat splenocytes were remarkably reduced by more than 500 times at 2 week PI and restored to normal level at 7 week PI. (+info)Paragonimiasis westermani with multifocal lesions in lungs and skin. (2/95)
We report a case of Paragonimus westermani infection with a reticulonodular lesion in the right lung, left pleural effusion, and a mobile subcutaneous mass. Analyses of pleural effusion and bronchoalveolar lavage fluid (BALF) showed marked eosinophilia and high levels of eosinophil cationic protein and interleukin (IL)-5. Transbronchial lung biopsy revealed the presence of pneumonia with mild eosinophilic infiltration but remarkable lymphocytic infiltration. In this patient, high IL-5 levels in both BALF and pleural effusion could explain the remarkable eosinophilia. (+info)Paragonimiasis miyazakii associated with bilateral pseudochylothorax. (3/95)
A 37-year-old man who suffered from bilateral pleural effusions, subcutaneous abdominal induration and blood eosinophilia, was admitted to our hospital. He had ingested raw crabs at a pub-restaurant before the onset of his symptoms. His pleural effusions were chyliform containing cholesterol crystals, and a high level of immunoglobulin E (36,580 IU/ml) and anti-Paragonimus miyazakii antibody were detected. He was effectively treated with praziquantel. This case suggests that paragonimiasis should be strongly suspected if blood eosinophilia, pseudochylothorax, and a high level of immunoglobulin E in pleural effusion are detected. (+info)Persisting antibody reaction in paragonimiasis after praziquantel treatment is elicited mainly by egg antigens. (4/95)
Antibody responses in serum and cerebrospinal fluid (CSF) samples from patients with active and chronic paragonimiasis and in sera from patients on whom follow-up studies were done after praziquantel treatment were analyzed using antigens of Paragonimus westermani prepared from eggs, metacercariae, juveniles of 4- and 7-week old, adult worms and recombinant protein of 28 kDa cruzipain-like cysteine protease (rPw28CCP). The patient sera/CSFs of active and chronic paragonimiasis revealed strong antibody reactions against the crude extracts of 4- and 7-week old juveniles as well as against those from egg and adult. rPw28CCP also showed specific reaction to the sera with active paragonimiasis. After the treatment, levels of specific antibodies in the sera gradually decreased to negative range in most patients. In some cases with persisting high antibody levels, however, the reactions at 27 kDa egg protein were sustained throughout the observation period of 34 months. The reactions at 35 and 32 kDa in adult extract and rPw28CCP disappeared rapidly after the treatment. Persistent antibody reactions even after successful treatment are provoked by continuous antigenic challenge from eggs which were not resolved by treatment. (+info)Excretory-secretory product of Paragonimus westermani newly excysted metacercariae inhibits superoxide production of granulocytes stimulated with IgG. (5/95)
It is well known that the cysteine proteases in excretory-secretory product (ESP) of Paragonimus westermani newly excysted metacercariae (PwNEM) are capable of degrading IgG in vitro. Recent evidence suggests that the IgG-coated surface, such as found on parasites, is one of the most effective physiologic stimuli for granulocyte activation. Therefore, this study was designed to investigate the effect of excretory-secretory product (ESP) of PwNEM on superoxide production of granulocytes stimulated with IgG. The 96-well plates were coated with human IgG (0, 10, 30, 100 micrograms/ml) in the absence or presence of ESP. When granulocytes were incubated in the wells coated with human IgG in the presence of ESP, the level of superoxide production of granulocytes was reduced to about 90% when compared to the cells incubated in the wells coated with IgG alone. This inhibitory effect of the ESP on IgG-induced superoxide production of granulocytes was concentration-dependent. These results suggest that ESP secreted by PwNEM may be important in the control of effector functions of granulocytes stimulated with IgG in human paragonimiasis. (+info)A case of chronic cerebral paragonimiasis westermani. (6/95)
We report a chronic cerebral paragonimiasis from a 41-year-old Korean man who complains a headache and weakness of left motor neuron components. Magnetic resonance images of the brain revealed conglomerates of multiple ring-like enhancements in temporo-occipital and frontal lobes of the right hemisphere. An intradermal test for paragonimiasis westermani was positive. The patient was born near an endemic area of paragonimiasis and used to eat boiled or grilled freshwater crayfish in his childhood. Nodules in the brain were resected through craniotomies. The eggs of P. westermani were identified pathologically and parasitologically in the calcified necrotic lesions. Examinations on sputum and fecal specimens for the eggs of P. westermani were shown to be negative and a chest radiograph was normal. It is presumed that the brain lesions were formed by P. westermani approximately 30 years ago. (+info)Paragonimosis in the Cajabamba and Condebamba districts, Cajamarca, Peru. (7/95)
Stool samples from 409 pre-school and school students, living in six villages of the Cajabamba and Condebamba districts, Cajamarca, Peru, were examined using wet preparations and Lumbreras' method, looking for Paragonimus eggs. Fecal and sputum samples from two children (0. 5%) of 6 and 8 year-old showed eggs of Paragonimus. One hundred and twenty freshwater crabs, Hypolobocera chilensis eigenmanni, were collected from the Condebamba valley and 21 (17.5%) of them were infected with P. mexicanus (syn. P. peruvianus) metacercariae. Our results show the persistence of Paragonimus in human beings and in the main source of infection, the crabs. (+info)Structural and immunological characteristics of a 28-kilodalton cruzipain-like cysteine protease of Paragonimus westermani expressed in the definitive host stage. (8/95)
A complete cDNA sequence encoding a 28-kDa cruzipain-like cysteine protease of adult Paragonimus westermani, termed Pw28CCP, was isolated from an adult cDNA library. The cDNA contained a single open reading frame of 975 bp encoding 325 amino acids, which exhibited the structural motif and domain organization characteristic of cysteine proteases of non-cathepsin Bs including a hydrophobic signal sequence, an ERFNIN motif, and essential cysteine residues as well as active sites in the mature catalytic region. Analysis of its phylogenetic position revealed that this novel enzyme belonged to the cruzipain-like cysteine proteases. The sequence of the first 13 amino acids predicted from the mature domain of Pw28CCP was in accord with that determined from the native 28-kDa enzyme purified from the adult worm. Expression of Pw28CCP was observed specifically in juvenile and adult worms, with a location in the intestinal epithelium, suggesting that this enzyme could be secreted and involved in nutrient uptake and immune modulation. The recombinant protein expressed in Escherichia coli was used to assess antigenicity by immunoblotting with sera from patients with active paragonimiasis and from those with other parasitic infections. The resulting sensitivity of 86.2% (56 of 65 samples) and specificity of 98% (147 of 150 samples) suggest its potential as an antigen for use in immunodiagnosis. (+info)Paragonimiasis is a tropical pulmonary disease caused by the infection of Paragonimus species, a type of lung fluke. The disease cycle begins when humans consume undercooked or raw crustaceans (such as crabs or crayfish) that contain the larval form of the parasite. Once ingested, the larvae penetrate the intestinal wall and migrate to the lungs, where they develop into adult worms and produce eggs.
Symptoms of paragonimiasis can vary depending on the severity of the infection and the location of the worms in the body. Common symptoms include coughing up blood (hemoptysis), chest pain, difficulty breathing, fever, and diarrhea. In some cases, the parasites may migrate to other organs such as the brain or liver, causing additional complications.
Diagnosis of paragonimiasis typically involves a combination of clinical symptoms, imaging studies (such as chest X-rays), and laboratory tests (such as stool or sputum analysis for parasite eggs). Treatment usually involves administration of antihelminthic drugs such as praziquantel or triclabendazole to kill the adult worms. Preventive measures include cooking crustaceans thoroughly before consumption, avoiding raw or undercooked seafood, and practicing good personal hygiene.
"Paragonimus" is a genus of lung flukes, which are parasitic flatworms that infect the lungs of humans and other mammals. The most common species that infect humans is Paragonimus westermani, also known as the oriental lung fluke.
Humans become infected with these parasites by eating raw or undercooked freshwater crustaceans (such as crabs or crayfish) that harbor the larval stage of the fluke. Once ingested, the larvae migrate from the intestines to the lungs, where they develop into adults and produce eggs. These eggs are coughed up and swallowed, and then passed in the feces. If the eggs reach fresh water, they hatch into miracidia, which infect snails, the first intermediate host.
Inside the snail, the parasites multiply asexually, and then emerge as cercariae, which encyst on the surface of crustaceans. When a human or another mammalian host eats the infected crustacean, the life cycle continues.
Paragonimiasis, the disease caused by Paragonimus infection, can lead to symptoms such as cough, chest pain, fever, and shortness of breath. In severe cases, it can cause lung damage and other complications.
Parasitic lung diseases refer to conditions caused by infection of the lungs by parasites. These are small organisms that live on or in a host organism and derive their sustenance at the expense of the host. Parasitic lung diseases can be caused by various types of parasites, including helminths (worms) and protozoa.
Examples of parasitic lung diseases include:
1. Pulmonary echinococcosis (hydatid disease): This is a rare infection caused by the larval stage of the tapeworm Echinococcus granulosus. The larvae form cysts in various organs, including the lungs.
2. Paragonimiasis: This is a food-borne lung fluke infection caused by Paragonimus westermani and other species. Humans become infected by eating raw or undercooked crustaceans (such as crabs or crayfish) that contain the larval stage of the parasite.
3. Toxocariasis: This is a soil-transmitted helminth infection caused by the roundworm Toxocara canis or T. cati, which are found in the intestines of dogs and cats. Humans become infected through accidental ingestion of contaminated soil, undercooked meat, or through contact with an infected animal's feces. Although the primary site of infection is the small intestine, larval migration can lead to lung involvement in some cases.
4. Amebic lung disease: This is a rare complication of amebiasis, which is caused by the protozoan Entamoeba histolytica. The parasite usually infects the large intestine, but it can spread to other organs, including the lungs, through the bloodstream.
5. Cryptosporidiosis: This is a waterborne protozoan infection caused by Cryptosporidium parvum or C. hominis. Although the primary site of infection is the small intestine, immunocompromised individuals can develop disseminated disease, including pulmonary involvement.
Symptoms of parasitic lung diseases vary depending on the specific organism and the severity of infection but may include cough, chest pain, shortness of breath, fever, and sputum production. Diagnosis typically involves a combination of clinical evaluation, imaging studies, and laboratory tests, such as stool or blood examinations for parasites or their antigens. Treatment depends on the specific organism but may include antiparasitic medications, supportive care, and management of complications.
"Paragonimus westermani" is a species of lung fluke that is known to cause paragonimiasis, which is a food-borne trematode infection. This parasite typically infects the lungs of humans and other mammals, although it can also be found in other organs such as the brain or skin.
Humans become infected with "Paragonimus westermani" by consuming raw or undercooked crustaceans, such as crabs or crayfish, that harbor the parasite's larvae. Once ingested, the larvae migrate from the intestines to the lungs, where they develop into adult flukes and produce eggs. These eggs are then coughed up and expelled from the body through sputum or feces, which can contaminate freshwater sources and infect new hosts.
Symptoms of paragonimiasis include coughing up blood, chest pain, fever, and difficulty breathing. In severe cases, the infection can lead to neurological symptoms if the flukes migrate to the brain. Treatment typically involves anti-parasitic medications such as praziquantel or triclabendazole.
Praziquantel is an anthelmintic medication, which is used to treat and prevent trematode (fluke) infections, including schistosomiasis (also known as bilharzia or snail fever), clonorchiasis, opisthorchiasis, paragonimiasis, and fasciolopsiasis. It works by causing severe spasms in the muscle cells of the parasites, ultimately leading to their death. Praziquantel is available in tablet form and is typically taken orally in a single dose, although the dosage may vary depending on the type and severity of the infection being treated.
It's important to note that praziquantel is not effective against tapeworm infections, and other medications such as niclosamide or albendazole are used instead for those infections. Also, Praziquantel should be taken under medical supervision, as it may have some side effects, including abdominal pain, nausea, vomiting, dizziness, and headache.
It's important to consult a healthcare professional before taking any medication.
Medical definitions typically focus on the potential risks or reactions related to a substance, rather than providing a general definition. In the context of medicine, shellfish are often defined by the allergens they contain, rather than as a culinary category.
According to the American College of Allergy, Asthma & Immunology (ACAAI), shellfish are divided into two categories: crustaceans and mollusks. Crustaceans include shrimp, crab, lobster, and crayfish. Mollusks include clams, mussels, oysters, scallops, octopus, and squid.
Shellfish allergies are one of the most common food allergies, and they can cause severe reactions, including anaphylaxis. Therefore, in a medical context, it's essential to be specific about which types of shellfish may pose a risk to an individual.
Antibodies are proteins produced by the immune system in response to the presence of a foreign substance, known as an antigen. They are capable of recognizing and binding to specific antigens, neutralizing or marking them for destruction by other immune cells.
Helminths are parasitic worms that can infect humans and animals. They include roundworms, tapeworms, and flukes, among others. Helminth infections can cause a range of symptoms, depending on the type of worm and the location of the infection.
Antibodies to helminths are produced by the immune system in response to an infection with one of these parasitic worms. These antibodies can be detected in the blood and serve as evidence of a current or past infection. They may also play a role in protecting against future infections with the same type of worm.
There are several different classes of antibodies, including IgA, IgD, IgE, IgG, and IgM. Antibodies to helminths are typically of the IgE class, which are associated with allergic reactions and the defense against parasites. IgE antibodies can bind to mast cells and basophils, triggering the release of histamine and other inflammatory mediators that help to protect against the worm.
In addition to IgE, other classes of antibodies may also be produced in response to a helminth infection. For example, IgG antibodies may be produced later in the course of the infection and can provide long-term immunity to reinfection. IgA antibodies may also be produced and can help to prevent the attachment and entry of the worm into the body.
Overall, the production of antibodies to helminths is an important part of the immune response to these parasitic worms. However, in some cases, the presence of these antibodies may also be associated with allergic reactions or other immunological disorders.
Anthelmintics are a type of medication used to treat infections caused by parasitic worms, also known as helminths. These medications work by either stunting the growth of the worms, paralyzing them, or killing them outright, allowing the body to expel the worms through normal bodily functions. Anthelmintics are commonly used to treat infections caused by roundworms, tapeworms, flukeworms, and hookworms. Examples of anthelmintic drugs include albendazole, mebendazole, praziquantel, and ivermectin.
I'm sorry for any confusion, but "Laos" is not a medical term. It is the name of a country, the Lao People's Democratic Republic, located in Southeast Asia. If you have any questions about medical terms or health-related topics, I'd be happy to try and help answer them!
Pleural effusion is a medical condition characterized by the abnormal accumulation of fluid in the pleural space, which is the thin, fluid-filled space that surrounds the lungs and lines the inside of the chest wall. This space typically contains a small amount of fluid to allow for smooth movement of the lungs during breathing. However, when an excessive amount of fluid accumulates, it can cause symptoms such as shortness of breath, coughing, and chest pain.
Pleural effusions can be caused by various underlying medical conditions, including pneumonia, heart failure, cancer, pulmonary embolism, and autoimmune disorders. The fluid that accumulates in the pleural space can be transudative or exudative, depending on the cause of the effusion. Transudative effusions are caused by increased pressure in the blood vessels or decreased protein levels in the blood, while exudative effusions are caused by inflammation, infection, or cancer.
Diagnosis of pleural effusion typically involves a physical examination, chest X-ray, and analysis of the fluid in the pleural space. Treatment depends on the underlying cause of the effusion and may include medications, drainage of the fluid, or surgery.
Brachyura is a term used in the classification of crustaceans, specifically referring to a group of decapods known as "true crabs." This infraorder includes a wide variety of crab species that are characterized by having a short and broad abdomen, which is typically tucked under the thorax and protected by the shell.
The term Brachyura comes from the Greek words "brachys," meaning short, and "oura," meaning tail. This refers to the reduced abdomen that distinguishes this group of crabs from other decapods such as shrimps, lobsters, and crayfish.
Brachyura species are found in a wide range of habitats, including freshwater, marine, and terrestrial environments. They can be found all over the world, with some species adapted to live in extreme conditions such as deep-sea hydrothermal vents or intertidal zones. Some well-known examples of Brachyura include the blue crab (Callinectes sapidus), the European shore crab (Carcinus maenas), and the coconut crab (Birgus latro).
I'm sorry for any confusion, but "Missouri" is not a medical term or concept. It is a geographical location, being the name of a state located in the central United States. If you have any questions related to medical terminology or concepts, I would be happy to help with those!
Food parasitology is not a commonly used term in medical or scientific communities. However, it generally refers to the study of parasites that are transmitted through food, including parasitic protozoa, helminths (worms), and arthropods (e.g., tapeworms, roundworms, Giardia, Cryptosporidium, etc.). Food parasitology involves understanding the life cycles, epidemiology, diagnosis, treatment, and prevention of these foodborne parasites. It is an important field within medical and veterinary parasitology, as well as food safety and public health.
I'm sorry for any confusion, but "Suburban Health" is not a recognized medical term or concept with a specific definition in the field of medicine. The term "suburban" generally refers to the residential areas surrounding a city or urban center, and health would refer to the physical and mental well-being of individuals living in those areas. However, there isn't a unique set of health issues or characteristics that define 'Suburban Health'.
Public health researchers might study the health disparities or common health issues in suburban areas compared to urban or rural areas, but this would not fall under a single medical definition. If you have more specific questions about health issues related to suburban living, I'd be happy to try and help with those!
Bithionol is an oral antiparasitic medication that has been used to treat infections caused by certain types of tapeworms, such as Paragonimus westermani (lung fluke) and Fasciolopsis buski (intestinal fluke). It works by inhibiting the metabolic processes of the parasites, which helps to eliminate them from the body.
Bithionol is no longer commonly used due to the availability of safer and more effective antiparasitic drugs. Its use may be associated with several side effects, including nausea, vomiting, diarrhea, abdominal pain, dizziness, and skin rashes. In some cases, it may also cause liver damage or allergic reactions.
It is important to note that bithionol should only be used under the supervision of a healthcare professional, as its use requires careful monitoring and dosage adjustment based on the patient's response to treatment.
Central nervous system helminthiasis is a medical condition that refers to the invasion and infection of the central nervous system (CNS), specifically the brain and spinal cord, by parasitic worms, also known as helminths. This rare but serious condition can occur when helminth larvae or eggs accidentally migrate from their usual location in the body to the CNS through the bloodstream or cerebrospinal fluid.
The most common types of helminths that can cause CNS helminthiasis include:
1. Neurocysticercosis: This is caused by the larval stage of the tapeworm Taenia solium, which typically infects the muscles and brain. However, when the larvae invade the CNS, they can form cysts that cause inflammation, swelling, and damage to brain tissue.
2. Echinococcosis: This is caused by the larval stage of the tapeworm Echinococcus granulosus or Echinococcus multilocularis. The larvae can form hydatid cysts in various organs, including the brain, leading to neurological symptoms.
3. Gnathostomiasis: This is caused by the larval stage of the nematode Gnathostoma spinigerum or Gnathostoma hispidum. The larvae can migrate to various organs, including the CNS, causing inflammation and damage to brain tissue.
4. Angiostrongyliasis: This is caused by the nematode Angiostrongylus cantonensis, which typically infects rats but can accidentally infect humans through contaminated food or water. The larvae can migrate to the CNS and cause eosinophilic meningitis, an inflammation of the membranes surrounding the brain and spinal cord.
Symptoms of CNS helminthiasis depend on the type of parasite involved, the location and extent of the infection, and the host's immune response. They can range from mild to severe and may include headache, seizures, weakness, numbness, vision changes, confusion, and cognitive impairment. Diagnosis is usually based on clinical presentation, imaging studies, and laboratory tests, such as serology or CSF analysis. Treatment depends on the type of parasite involved and may include antiparasitic drugs, corticosteroids, and supportive care. Prevention measures include avoiding contaminated food and water, practicing good hygiene, and using insect repellents to prevent mosquito-borne infections.
Astacoidea is a superfamily of freshwater decapod crustaceans, which includes crayfish and lobsters. This superfamily is divided into two families: Astacidae, which contains the true crayfishes, and Cambaridae, which contains the North American burrowing crayfishes. These animals are characterized by a robust exoskeleton, antennae, and pincers, and they are primarily scavengers and predators. They are found in freshwater environments around the world, and some species are of commercial importance as a food source.
A "Parasite Egg Count" is a laboratory measurement used to estimate the number of parasitic eggs present in a fecal sample. It is commonly used in veterinary and human medicine to diagnose and monitor parasitic infections, such as those caused by roundworms, hookworms, tapeworms, and other intestinal helminths (parasitic worms).
The most common method for measuring parasite egg counts is the McMaster technique. This involves mixing a known volume of feces with a flotation solution, which causes the eggs to float to the top of the mixture. A small sample of this mixture is then placed on a special counting chamber and examined under a microscope. The number of eggs present in the sample is then multiplied by a dilution factor to estimate the total number of eggs per gram (EPG) of feces.
Parasite egg counts can provide valuable information about the severity of an infection, as well as the effectiveness of treatment. However, it is important to note that not all parasitic infections produce visible eggs in the feces, and some parasites may only shed eggs intermittently. Therefore, a negative egg count does not always rule out the presence of a parasitic infection.
Helminth antigens refer to the proteins or other molecules found on the surface or within helminth parasites that can stimulate an immune response in a host organism. Helminths are large, multicellular parasitic worms that can infect various tissues and organs in humans and animals, causing diseases such as schistosomiasis, lymphatic filariasis, and soil-transmitted helminthiases.
Helminth antigens can be recognized by the host's immune system as foreign invaders, leading to the activation of various immune cells and the production of antibodies. However, many helminths have evolved mechanisms to evade or suppress the host's immune response, allowing them to establish long-term infections.
Studying helminth antigens is important for understanding the immunology of helminth infections and developing new strategies for diagnosis, treatment, and prevention. Some researchers have also explored the potential therapeutic use of helminth antigens or whole helminths as a way to modulate the immune system and treat autoimmune diseases or allergies. However, more research is needed to determine the safety and efficacy of these approaches.
Eosinophilia is a medical condition characterized by an abnormally high concentration of eosinophils in the circulating blood. Eosinophils are a type of white blood cell that play an important role in the immune system, particularly in fighting off parasitic infections and regulating allergic reactions. However, when their numbers become excessively high, they can contribute to tissue damage and inflammation.
Eosinophilia is typically defined as a count of more than 500 eosinophils per microliter of blood. Mild eosinophilia (up to 1,500 cells/μL) may not cause any symptoms and may be discovered during routine blood tests. However, higher levels of eosinophilia can lead to various symptoms such as coughing, wheezing, skin rashes, and organ damage, depending on the underlying cause.
The causes of eosinophilia are varied and can include allergic reactions, parasitic infections, autoimmune disorders, certain medications, and some types of cancer. Accurate diagnosis and treatment of eosinophilia require identification and management of the underlying cause.
Metacercariae are the encysted, infective stage of certain trematode (flatworm) parasites, such as those that cause intestinal schistosomiasis and fascioliasis. They form following a series of developmental stages within intermediate hosts like snails, fish, or crustaceans. Once ingested by the definitive host (usually a mammal), metacercariae excyst in the digestive tract and migrate to their target organs, where they mature into adults and reproduce.
'Fasciola' is the name of a genus of parasitic flatworms, also known as flukes, that infect the livers of various animals including sheep, cattle, and humans. The two most common species are Fasciola hepatica and Fasciola gigantica. These parasites have a complex life cycle involving aquatic snails as intermediate hosts and can cause significant damage to the liver and bile ducts in their definitive host, resulting in a disease known as fascioliasis. Infection typically occurs through the consumption of contaminated watercress or other aquatic plants.
Clonorchiasis is a parasitic infection caused by the trematode worm Clonorchis sinensis, also known as the Chinese liver fluke. This flatworm infects the bile ducts and liver of humans and other animals, leading to inflammation, obstruction, and potential complications such as cholangitis, cirrhosis, and cholangiocarcinoma (bile duct cancer).
Humans become infected with Clonorchis sinensis by consuming raw or undercooked freshwater fish that contain metacercariae, the infective larval stage of the parasite. The larvae excyst in the small intestine and migrate to the bile ducts, where they mature into adult worms and reproduce. Eggs are released into the stool and can contaminate water sources if proper sanitation is not maintained.
Symptoms of clonorchiasis may include abdominal pain, diarrhea, nausea, vomiting, and liver enlargement. In severe cases, patients may experience jaundice, ascites (fluid accumulation in the abdomen), and weight loss. Diagnosis is typically made by detecting eggs in stool samples or identifying the parasite in biopsied tissue. Treatment involves administering anthelmintic drugs such as praziquantel to eliminate the infection. Preventive measures include avoiding consumption of raw or undercooked fish and maintaining good hygiene practices.
I'm not aware of any medical condition or term that is specifically associated with or referred to as "Cameroon." Cameroon is a country located in Central Africa, known for its rich biodiversity and cultural diversity. If you have more context about why you are looking for a medical definition of "Cameroon," I may be able to provide a more helpful response.
Trematoda is a class of parasitic flatworms, also known as flukes. They have a complex life cycle involving one or more intermediate hosts and a definitive host. Adult trematodes are typically leaf-shaped and range in size from a few millimeters to several centimeters.
They have a characteristic oral sucker surrounding the mouth and a ventral sucker, which they use for locomotion and attachment to their host's tissues. Trematodes infect various organs of their hosts, including the liver, lungs, blood vessels, and intestines, causing a range of diseases in humans and animals.
Examples of human-infecting trematodes include Schistosoma spp., which cause schistosomiasis (also known as bilharzia), and Fasciola hepatica, which causes fascioliasis (liver fluke disease). Trematode infections are typically treated with antiparasitic drugs.
An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.