Central Nervous System: The main information-processing organs of the nervous system, consisting of the brain, spinal cord, and meninges.Nervous System: The entire nerve apparatus, composed of a central part, the brain and spinal cord, and a peripheral part, the cranial and spinal nerves, autonomic ganglia, and plexuses. (Stedman, 26th ed)Central Nervous System Diseases: Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.Peripheral Nervous System: The nervous system outside of the brain and spinal cord. The peripheral nervous system has autonomic and somatic divisions. The autonomic nervous system includes the enteric, parasympathetic, and sympathetic subdivisions. The somatic nervous system includes the cranial and spinal nerves and their ganglia and the peripheral sensory receptors.Enteric Nervous System: Two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gallbladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation. (From Kandel, Schwartz, and Jessel, Principles of Neural Science, 3d ed, p766)Central Nervous System Neoplasms: Benign and malignant neoplastic processes that arise from or secondarily involve the brain, spinal cord, or meninges.Autonomic Nervous System: The ENTERIC NERVOUS SYSTEM; PARASYMPATHETIC NERVOUS SYSTEM; and SYMPATHETIC NERVOUS SYSTEM taken together. Generally speaking, the autonomic nervous system regulates the internal environment during both peaceful activity and physical or emotional stress. Autonomic activity is controlled and integrated by the CENTRAL NERVOUS SYSTEM, especially the HYPOTHALAMUS and the SOLITARY NUCLEUS, which receive information relayed from VISCERAL AFFERENTS.Sympathetic Nervous System: The thoracolumbar division of the autonomic nervous system. Sympathetic preganglionic fibers originate in neurons of the intermediolateral column of the spinal cord and project to the paravertebral and prevertebral ganglia, which in turn project to target organs. The sympathetic nervous system mediates the body's response to stressful situations, i.e., the fight or flight reactions. It often acts reciprocally to the parasympathetic system.Nervous System Physiological Phenomena: Characteristic properties and processes of the NERVOUS SYSTEM as a whole or with reference to the peripheral or the CENTRAL NERVOUS SYSTEM.Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.Central Nervous System Infections: Pathogenic infections of the brain, spinal cord, and meninges. DNA VIRUS INFECTIONS; RNA VIRUS INFECTIONS; BACTERIAL INFECTIONS; MYCOPLASMA INFECTIONS; SPIROCHAETALES INFECTIONS; fungal infections; PROTOZOAN INFECTIONS; HELMINTHIASIS; and PRION DISEASES may involve the central nervous system as a primary or secondary process.Nervous System Diseases: Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle.Nervous System Neoplasms: Benign and malignant neoplastic processes arising from or involving components of the central, peripheral, and autonomic nervous systems, cranial nerves, and meninges. Included in this category are primary and metastatic nervous system neoplasms.Neurons: The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.Central Nervous System Viral Diseases: Viral infections of the brain, spinal cord, meninges, or perimeningeal spaces.Spinal Cord: A cylindrical column of tissue that lies within the vertebral canal. It is composed of WHITE MATTER and GRAY MATTER.Vasculitis, Central Nervous System: Inflammation of blood vessels within the central nervous system. Primary vasculitis is usually caused by autoimmune or idiopathic factors, while secondary vasculitis is caused by existing disease process. Clinical manifestations are highly variable but include HEADACHE; SEIZURES; behavioral alterations; INTRACRANIAL HEMORRHAGES; TRANSIENT ISCHEMIC ATTACK; and BRAIN INFARCTION. (From Adams et al., Principles of Neurology, 6th ed, pp856-61)Neuroglia: The non-neuronal cells of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu, participate in the BLOOD-BRAIN BARRIER and BLOOD-RETINAL BARRIER, form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear.Nerve Tissue ProteinsAxons: Nerve fibers that are capable of rapidly conducting impulses away from the neuron cell body.Central Nervous System Agents: A class of drugs producing both physiological and psychological effects through a variety of mechanisms. They can be divided into "specific" agents, e.g., affecting an identifiable molecular mechanism unique to target cells bearing receptors for that agent, and "nonspecific" agents, those producing effects on different target cells and acting by diverse molecular mechanisms. Those with nonspecific mechanisms are generally further classed according to whether they produce behavioral depression or stimulation. Those with specific mechanisms are classed by locus of action or specific therapeutic use. (From Gilman AG, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p252)Trauma, Nervous System: Traumatic injuries to the brain, cranial nerves, spinal cord, autonomic nervous system, or neuromuscular system, including iatrogenic injuries induced by surgical procedures.Myelin Sheath: The lipid-rich sheath surrounding AXONS in both the CENTRAL NERVOUS SYSTEMS and PERIPHERAL NERVOUS SYSTEM. The myelin sheath is an electrical insulator and allows faster and more energetically efficient conduction of impulses. The sheath is formed by the cell membranes of glial cells (SCHWANN CELLS in the peripheral and OLIGODENDROGLIA in the central nervous system). Deterioration of the sheath in DEMYELINATING DISEASES is a serious clinical problem.Gene Expression Regulation, Developmental: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action during the developmental stages of an organism.Central Nervous System Fungal Infections: MYCOSES of the brain, spinal cord, and meninges which may result in ENCEPHALITIS; MENINGITIS, FUNGAL; MYELITIS; BRAIN ABSCESS; and EPIDURAL ABSCESS. Certain types of fungi may produce disease in immunologically normal hosts, while others are classified as opportunistic pathogens, causing illness primarily in immunocompromised individuals (e.g., ACQUIRED IMMUNODEFICIENCY SYNDROME).Autonomic Nervous System Diseases: Diseases of the parasympathetic or sympathetic divisions of the AUTONOMIC NERVOUS SYSTEM; which has components located in the CENTRAL NERVOUS SYSTEM and PERIPHERAL NERVOUS SYSTEM. Autonomic dysfunction may be associated with HYPOTHALAMIC DISEASES; BRAIN STEM disorders; SPINAL CORD DISEASES; and PERIPHERAL NERVOUS SYSTEM DISEASES. Manifestations include impairments of vegetative functions including the maintenance of BLOOD PRESSURE; HEART RATE; pupil function; SWEATING; REPRODUCTIVE AND URINARY PHYSIOLOGY; and DIGESTION.Peripheral Nerves: The nerves outside of the brain and spinal cord, including the autonomic, cranial, and spinal nerves. Peripheral nerves contain non-neuronal cells and connective tissue as well as axons. The connective tissue layers include, from the outside to the inside, the epineurium, the perineurium, and the endoneurium.In Situ Hybridization: A technique that localizes specific nucleic acid sequences within intact chromosomes, eukaryotic cells, or bacterial cells through the use of specific nucleic acid-labeled probes.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Parasympathetic Nervous System: The craniosacral division of the autonomic nervous system. The cell bodies of the parasympathetic preganglionic fibers are in brain stem nuclei and in the sacral spinal cord. They synapse in cranial autonomic ganglia or in terminal ganglia near target organs. The parasympathetic nervous system generally acts to conserve resources and restore homeostasis, often with effects reciprocal to the sympathetic nervous system.Astrocytes: A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with MICROGLIA) respond to injury.Central Nervous System Bacterial Infections: Bacterial infections of the brain, spinal cord, and meninges, including infections involving the perimeningeal spaces.Blood-Brain Barrier: Specialized non-fenestrated tightly-joined ENDOTHELIAL CELLS with TIGHT JUNCTIONS that form a transport barrier for certain substances between the cerebral capillaries and the BRAIN tissue.Peripheral Nervous System Diseases: Diseases of the peripheral nerves external to the brain and spinal cord, which includes diseases of the nerve roots, ganglia, plexi, autonomic nerves, sensory nerves, and motor nerves.Demyelinating Diseases: Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.Mice, Inbred C57BLOligodendroglia: A class of large neuroglial (macroglial) cells in the central nervous system. Oligodendroglia may be called interfascicular, perivascular, or perineuronal (not the same as SATELLITE CELLS, PERINEURONAL of GANGLIA) according to their location. They form the insulating MYELIN SHEATH of axons in the central nervous system.Brain Diseases: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.Tuberculosis, Central Nervous System: Tuberculosis of the brain, spinal cord, or meninges (TUBERCULOSIS, MENINGEAL), most often caused by MYCOBACTERIUM TUBERCULOSIS and rarely by MYCOBACTERIUM BOVIS. The infection may be limited to the nervous system or coexist in other organs (e.g., TUBERCULOSIS, PULMONARY). The organism tends to seed the meninges causing a diffuse meningitis and leads to the formation of TUBERCULOMA, which may occur within the brain, spinal cord, or perimeningeal spaces. Tuberculous involvement of the vertebral column (TUBERCULOSIS, SPINAL) may result in nerve root or spinal cord compression. (From Adams et al., Principles of Neurology, 6th ed, pp717-20)Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Encephalomyelitis, Autoimmune, Experimental: An experimental animal model for central nervous system demyelinating disease. Inoculation with a white matter emulsion combined with FREUND'S ADJUVANT, myelin basic protein, or purified central myelin triggers a T cell-mediated immune response directed towards central myelin. The pathologic features are similar to MULTIPLE SCLEROSIS, including perivascular and periventricular foci of inflammation and demyelination. Subpial demyelination underlying meningeal infiltrations also occurs, which is also a feature of ENCEPHALOMYELITIS, ACUTE DISSEMINATED. Passive immunization with T-cells from an afflicted animal to a normal animal also induces this condition. (From Immunol Res 1998;17(1-2):217-27; Raine CS, Textbook of Neuropathology, 2nd ed, p604-5)Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Cerebrospinal Fluid: A watery fluid that is continuously produced in the CHOROID PLEXUS and circulates around the surface of the BRAIN; SPINAL CORD; and in the CEREBRAL VENTRICLES.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.Drosophila Proteins: Proteins that originate from insect species belonging to the genus DROSOPHILA. The proteins from the most intensely studied species of Drosophila, DROSOPHILA MELANOGASTER, are the subject of much interest in the area of MORPHOGENESIS and development.Encephalomyelitis: A general term indicating inflammation of the BRAIN and SPINAL CORD, often used to indicate an infectious process, but also applicable to a variety of autoimmune and toxic-metabolic conditions. There is significant overlap regarding the usage of this term and ENCEPHALITIS in the literature.Signal Transduction: The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.Mice, Knockout: Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.Ganglia: Clusters of multipolar neurons surrounded by a capsule of loosely organized CONNECTIVE TISSUE located outside the CENTRAL NERVOUS SYSTEM.Embryo, Nonmammalian: The developmental entity of a fertilized egg (ZYGOTE) in animal species other than MAMMALS. For chickens, use CHICK EMBRYO.Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)Sciatic Nerve: A nerve which originates in the lumbar and sacral spinal cord (L4 to S3) and supplies motor and sensory innervation to the lower extremity. The sciatic nerve, which is the main continuation of the sacral plexus, is the largest nerve in the body. It has two major branches, the TIBIAL NERVE and the PERONEAL NERVE.Drosophila: A genus of small, two-winged flies containing approximately 900 described species. These organisms are the most extensively studied of all genera from the standpoint of genetics and cytology.Brain Chemistry: Changes in the amounts of various chemicals (neurotransmitters, receptors, enzymes, and other metabolites) specific to the area of the central nervous system contained within the head. These are monitored over time, during sensory stimulation, or under different disease states.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Nerve Regeneration: Renewal or physiological repair of damaged nerve tissue.Neuropeptides: Peptides released by NEURONS as intercellular messengers. Many neuropeptides are also hormones released by non-neuronal cells.Microglia: The third type of glial cell, along with astrocytes and oligodendrocytes (which together form the macroglia). Microglia vary in appearance depending on developmental stage, functional state, and anatomical location; subtype terms include ramified, perivascular, ameboid, resting, and activated. Microglia clearly are capable of phagocytosis and play an important role in a wide spectrum of neuropathologies. They have also been suggested to act in several other roles including in secretion (e.g., of cytokines and neural growth factors), in immunological processing (e.g., antigen presentation), and in central nervous system development and remodeling.Cell Differentiation: Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.Mice, Transgenic: Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.Myelin Proteins: MYELIN-specific proteins that play a structural or regulatory role in the genesis and maintenance of the lamellar MYELIN SHEATH structure.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Cerebellum: The part of brain that lies behind the BRAIN STEM in the posterior base of skull (CRANIAL FOSSA, POSTERIOR). It is also known as the "little brain" with convolutions similar to those of CEREBRAL CORTEX, inner white matter, and deep cerebellar nuclei. Its function is to coordinate voluntary movements, maintain balance, and learn motor skills.Neurogenesis: Formation of NEURONS which involves the differentiation and division of STEM CELLS in which one or both of the daughter cells become neurons.Tissue Distribution: Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.Nervous System Malformations: Structural abnormalities of the central or peripheral nervous system resulting primarily from defects of embryogenesis.Schwann Cells: Neuroglial cells of the peripheral nervous system which form the insulating myelin sheaths of peripheral axons.Encephalitis: Inflammation of the BRAIN due to infection, autoimmune processes, toxins, and other conditions. Viral infections (see ENCEPHALITIS, VIRAL) are a relatively frequent cause of this condition.Motor Neurons: Neurons which activate MUSCLE CELLS.Encephalitis, Viral: Inflammation of brain parenchymal tissue as a result of viral infection. Encephalitis may occur as primary or secondary manifestation of TOGAVIRIDAE INFECTIONS; HERPESVIRIDAE INFECTIONS; ADENOVIRIDAE INFECTIONS; FLAVIVIRIDAE INFECTIONS; BUNYAVIRIDAE INFECTIONS; PICORNAVIRIDAE INFECTIONS; PARAMYXOVIRIDAE INFECTIONS; ORTHOMYXOVIRIDAE INFECTIONS; RETROVIRIDAE INFECTIONS; and ARENAVIRIDAE INFECTIONS.Autoimmune Diseases of the Nervous System: Disorders caused by cellular or humoral immune responses primarily directed towards nervous system autoantigens. The immune response may be directed towards specific tissue components (e.g., myelin) and may be limited to the central nervous system (e.g., MULTIPLE SCLEROSIS) or the peripheral nervous system (e.g., GUILLAIN-BARRE SYNDROME).Nerve Growth Factors: Factors which enhance the growth potentialities of sensory and sympathetic nerve cells.Meningoencephalitis: An inflammatory process involving the brain (ENCEPHALITIS) and meninges (MENINGITIS), most often produced by pathogenic organisms which invade the central nervous system, and occasionally by toxins, autoimmune disorders, and other conditions.Heart Rate: The number of times the HEART VENTRICLES contract per unit of time, usually per minute.Ganglia, Spinal: Sensory ganglia located on the dorsal spinal roots within the vertebral column. The spinal ganglion cells are pseudounipolar. The single primary branch bifurcates sending a peripheral process to carry sensory information from the periphery and a central branch which relays that information to the spinal cord or brain.Ganglia, Invertebrate: Clusters of neuronal cell bodies in invertebrates. Invertebrate ganglia may also contain neuronal processes and non-neuronal supporting cells. Many invertebrate ganglia are favorable subjects for research because they have small numbers of functional neuronal types which can be identified from one animal to another.Neural Crest: The two longitudinal ridges along the PRIMITIVE STREAK appearing near the end of GASTRULATION during development of nervous system (NEURULATION). The ridges are formed by folding of NEURAL PLATE. Between the ridges is a neural groove which deepens as the fold become elevated. When the folds meet at midline, the groove becomes a closed tube, the NEURAL TUBE.Leeches: Annelids of the class Hirudinea. Some species, the bloodsuckers, may become temporarily parasitic upon animals, including man. Medicinal leeches (HIRUDO MEDICINALIS) have been used therapeutically for drawing blood since ancient times.Animals, Newborn: Refers to animals in the period of time just after birth.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Neurites: In tissue culture, hairlike projections of neurons stimulated by growth factors and other molecules. These projections may go on to form a branched tree of dendrites or a single axon or they may be reabsorbed at a later stage of development. "Neurite" may refer to any filamentous or pointed outgrowth of an embryonal or tissue-culture neural cell.Cerebral Cortex: The thin layer of GRAY MATTER on the surface of the CEREBRAL HEMISPHERES that develops from the TELENCEPHALON and folds into gyri and sulchi. It reaches its highest development in humans and is responsible for intellectual faculties and higher mental functions.Injections, Intraventricular: Injections into the cerebral ventricles.Drosophila melanogaster: A species of fruit fly much used in genetics because of the large size of its chromosomes.Glial Fibrillary Acidic Protein: An intermediate filament protein found only in glial cells or cells of glial origin. MW 51,000.Zebrafish: An exotic species of the family CYPRINIDAE, originally from Asia, that has been introduced in North America. They are used in embryological studies and to study the effects of certain chemicals on development.Gene Expression: The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.Brain Stem: The part of the brain that connects the CEREBRAL HEMISPHERES with the SPINAL CORD. It consists of the MESENCEPHALON; PONS; and MEDULLA OBLONGATA.Neurotransmitter Agents: Substances used for their pharmacological actions on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.Stem Cells: Relatively undifferentiated cells that retain the ability to divide and proliferate throughout postnatal life to provide progenitor cells that can differentiate into specialized cells.Organ Specificity: Characteristic restricted to a particular organ of the body, such as a cell type, metabolic response or expression of a particular protein or antigen.Myelin Basic Protein: An abundant cytosolic protein that plays a critical role in the structure of multilamellar myelin. Myelin basic protein binds to the cytosolic sides of myelin cell membranes and causes a tight adhesion between opposing cell membranes.Transcription Factors: Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.Norepinephrine: Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.Synapses: Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.Meninges: The three membranes that cover the BRAIN and the SPINAL CORD. They are the dura mater, the arachnoid, and the pia mater.Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.Chick Embryo: The developmental entity of a fertilized chicken egg (ZYGOTE). The developmental process begins about 24 h before the egg is laid at the BLASTODISC, a small whitish spot on the surface of the EGG YOLK. After 21 days of incubation, the embryo is fully developed before hatching.Larva: Wormlike or grublike stage, following the egg in the life cycle of insects, worms, and other metamorphosing animals.Hippocampus: A curved elevation of GRAY MATTER extending the entire length of the floor of the TEMPORAL HORN of the LATERAL VENTRICLE (see also TEMPORAL LOBE). The hippocampus proper, subiculum, and DENTATE GYRUS constitute the hippocampal formation. Sometimes authors include the ENTORHINAL CORTEX in the hippocampal formation.Gene Expression Regulation: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.Animals, Genetically Modified: ANIMALS whose GENOME has been altered by GENETIC ENGINEERING, or their offspring.Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.Sequence Homology, Amino Acid: The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.Neuroimmunomodulation: The biochemical and electrophysiological interactions between the NERVOUS SYSTEM and IMMUNE SYSTEM.Cell Movement: The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.Lupus Vasculitis, Central Nervous System: Central nervous system vasculitis that is associated with SYSTEMIC LUPUS ERYTHEMATOSUS. Clinical manifestations may include DEMENTIA; SEIZURES; CRANIAL NERVE DISEASES; HEMIPARESIS; BLINDNESS; DYSPHASIA; and other neurological disorders.Behavior, Animal: The observable response an animal makes to any situation.Embryo, Mammalian: The entity of a developing mammal (MAMMALS), generally from the cleavage of a ZYGOTE to the end of embryonic differentiation of basic structures. For the human embryo, this represents the first two months of intrauterine development preceding the stages of the FETUS.Magnetic Resonance Imaging: Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.Cranial Nerves: Twelve pairs of nerves that carry general afferent, visceral afferent, special afferent, somatic efferent, and autonomic efferent fibers.Hypothalamus: Ventral part of the DIENCEPHALON extending from the region of the OPTIC CHIASM to the caudal border of the MAMMILLARY BODIES and forming the inferior and lateral walls of the THIRD VENTRICLE.Homeodomain Proteins: Proteins encoded by homeobox genes (GENES, HOMEOBOX) that exhibit structural similarity to certain prokaryotic and eukaryotic DNA-binding proteins. Homeodomain proteins are involved in the control of gene expression during morphogenesis and development (GENE EXPRESSION REGULATION, DEVELOPMENTAL).Synaptic Transmission: The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Models, Biological: Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.Nerve Tissue: Differentiated tissue of the central nervous system composed of NERVE CELLS, fibers, DENDRITES, and specialized supporting cells.Neurons, Afferent: Neurons which conduct NERVE IMPULSES to the CENTRAL NERVOUS SYSTEM.Neural Stem Cells: Self-renewing cells that generate the main phenotypes of the nervous system in both the embryo and adult. Neural stem cells are precursors to both NEURONS and NEUROGLIA.Body Patterning: The processes occurring in early development that direct morphogenesis. They specify the body plan ensuring that cells will proceed to differentiate, grow, and diversify in size and shape at the correct relative positions. Included are axial patterning, segmentation, compartment specification, limb position, organ boundary patterning, blood vessel patterning, etc.Cloning, Molecular: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.Rats, Wistar: A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.Neuronal Plasticity: The capacity of the NERVOUS SYSTEM to change its reactivity as the result of successive activations.Spinal Cord Neoplasms: Benign and malignant neoplasms which occur within the substance of the spinal cord (intramedullary neoplasms) or in the space between the dura and spinal cord (intradural extramedullary neoplasms). The majority of intramedullary spinal tumors are primary CNS neoplasms including ASTROCYTOMA; EPENDYMOMA; and LIPOMA. Intramedullary neoplasms are often associated with SYRINGOMYELIA. The most frequent histologic types of intradural-extramedullary tumors are MENINGIOMA and NEUROFIBROMA.Myelin-Associated Glycoprotein: A myelin protein found in the periaxonal membrane of both the central and peripheral nervous systems myelin sheaths. It binds to cells surface receptors found on AXONS and may regulate cellular interactions between MYELIN and AXONS.Retina: The ten-layered nervous tissue membrane of the eye. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent.Cell Line: Established cell cultures that have the potential to propagate indefinitely.Blood Pressure: PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.Membrane Proteins: Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.Sympathectomy, Chemical: Sympathectomy using chemicals (e.g., 6-hydroxydopamine or guanethidine) which selectively and reversibly destroy adrenergic nerve endings while leaving cholinergic nerve endings intact.DNA, Complementary: Single-stranded complementary DNA synthesized from an RNA template by the action of RNA-dependent DNA polymerase. cDNA (i.e., complementary DNA, not circular DNA, not C-DNA) is used in a variety of molecular cloning experiments as well as serving as a specific hybridization probe.Sensory Receptor Cells: Specialized afferent neurons capable of transducing sensory stimuli into NERVE IMPULSES to be transmitted to the CENTRAL NERVOUS SYSTEM. Sometimes sensory receptors for external stimuli are called exteroceptors; for internal stimuli are called interoceptors and proprioceptors.Meningitis, Viral: Viral infections of the leptomeninges and subarachnoid space. TOGAVIRIDAE INFECTIONS; FLAVIVIRIDAE INFECTIONS; RUBELLA; BUNYAVIRIDAE INFECTIONS; ORBIVIRUS infections; PICORNAVIRIDAE INFECTIONS; ORTHOMYXOVIRIDAE INFECTIONS; RHABDOVIRIDAE INFECTIONS; ARENAVIRIDAE INFECTIONS; HERPESVIRIDAE INFECTIONS; ADENOVIRIDAE INFECTIONS; JC VIRUS infections; and RETROVIRIDAE INFECTIONS may cause this form of meningitis. Clinical manifestations include fever, headache, neck pain, vomiting, PHOTOPHOBIA, and signs of meningeal irritation. (From Joynt, Clinical Neurology, 1996, Ch26, pp1-3)Basic Helix-Loop-Helix Transcription Factors: A family of DNA-binding transcription factors that contain a basic HELIX-LOOP-HELIX MOTIF.Optic Nerve: The 2nd cranial nerve which conveys visual information from the RETINA to the brain. The nerve carries the axons of the RETINAL GANGLION CELLS which sort at the OPTIC CHIASM and continue via the OPTIC TRACTS to the brain. The largest projection is to the lateral geniculate nuclei; other targets include the SUPERIOR COLLICULI and the SUPRACHIASMATIC NUCLEI. Though known as the second cranial nerve, it is considered part of the CENTRAL NERVOUS SYSTEM.Vagus Nerve: The 10th cranial nerve. The vagus is a mixed nerve which contains somatic afferents (from skin in back of the ear and the external auditory meatus), visceral afferents (from the pharynx, larynx, thorax, and abdomen), parasympathetic efferents (to the thorax and abdomen), and efferents to striated muscle (of the larynx and pharynx).Digestive System: A group of organs stretching from the MOUTH to the ANUS, serving to breakdown foods, assimilate nutrients, and eliminate waste. In humans, the digestive system includes the GASTROINTESTINAL TRACT and the accessory glands (LIVER; BILIARY TRACT; PANCREAS).Central Nervous System Protozoal Infections: Infections of the brain, spinal cord, or meninges by single celled organisms of the former subkingdom known as protozoa. The central nervous system may be the primary or secondary site of protozoal infection. These diseases may occur as OPPORTUNISTIC INFECTIONS or arise in immunocompetent hosts.AIDS Dementia Complex: A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)Peripheral Nervous System Neoplasms: Neoplasms which arise from peripheral nerve tissue. This includes NEUROFIBROMAS; SCHWANNOMAS; GRANULAR CELL TUMORS; and malignant peripheral NERVE SHEATH NEOPLASMS. (From DeVita Jr et al., Cancer: Principles and Practice of Oncology, 5th ed, pp1750-1)Rhombencephalon: The posterior of the three primitive cerebral vesicles of an embryonic brain. It consists of myelencephalon, metencephalon, and isthmus rhombencephali from which develop the major BRAIN STEM components, such as MEDULLA OBLONGATA from the myelencephalon, CEREBELLUM and PONS from the metencephalon, with the expanded cavity forming the FOURTH VENTRICLE.Meningeal Neoplasms: Benign and malignant neoplastic processes that arise from or secondarily involve the meningeal coverings of the brain and spinal cord.Reverse Transcriptase Polymerase Chain Reaction: A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.Hirschsprung Disease: Congenital MEGACOLON resulting from the absence of ganglion cells (aganglionosis) in a distal segment of the LARGE INTESTINE. The aganglionic segment is permanently contracted thus causing dilatation proximal to it. In most cases, the aganglionic segment is within the RECTUM and SIGMOID COLON.Blotting, Western: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.Embryonic and Fetal Development: Morphological and physiological development of EMBRYOS or FETUSES.Telencephalon: The anterior subdivision of the embryonic PROSENCEPHALON or the corresponding part of the adult prosencephalon that includes the cerebrum and associated structures.Myelin-Oligodendrocyte Glycoprotein: A transmembrane protein present in the MYELIN SHEATH of the CENTRAL NERVOUS SYSTEM. It is one of the main autoantigens implicated in the pathogenesis of MULTIPLE SCLEROSIS.Green Fluorescent Proteins: Protein analogs and derivatives of the Aequorea victoria green fluorescent protein that emit light (FLUORESCENCE) when excited with ULTRAVIOLET RAYS. They are used in REPORTER GENES in doing GENETIC TECHNIQUES. Numerous mutants have been made to emit other colors or be sensitive to pH.Lymnaea: A genus of dextrally coiled freshwater snails that includes some species of importance as intermediate hosts of parasitic flukes.Motor Activity: The physical activity of a human or an animal as a behavioral phenomenon.Cell Adhesion Molecules, Neuronal: Surface ligands that mediate cell-to-cell adhesion and function in the assembly and interconnection of the vertebrate nervous system. These molecules promote cell adhesion via a homophilic mechanism. These are not to be confused with NEURAL CELL ADHESION MOLECULES, now known to be expressed in a variety of tissues and cell types in addition to nervous tissue.Neurofilament Proteins: Type III intermediate filament proteins that assemble into neurofilaments, the major cytoskeletal element in nerve axons and dendrites. They consist of three distinct polypeptides, the neurofilament triplet. Types I, II, and IV intermediate filament proteins form other cytoskeletal elements such as keratins and lamins. It appears that the metabolism of neurofilaments is disturbed in Alzheimer's disease, as indicated by the presence of neurofilament epitopes in the neurofibrillary tangles, as well as by the severe reduction of the expression of the gene for the light neurofilament subunit of the neurofilament triplet in brains of Alzheimer's patients. (Can J Neurol Sci 1990 Aug;17(3):302)Zebrafish Proteins: Proteins obtained from the ZEBRAFISH. Many of the proteins in this species have been the subject of studies involving basic embryological development (EMBRYOLOGY).Theilovirus: A species of CARDIOVIRUS which contains three strains: Theiler's murine encephalomyelitis virus, Vilyuisk human encephalomyelitis virus, and Rat encephalomyelitis virus.Meningitis: Inflammation of the coverings of the brain and/or spinal cord, which consist of the PIA MATER; ARACHNOID; and DURA MATER. Infections (viral, bacterial, and fungal) are the most common causes of this condition, but subarachnoid hemorrhage (HEMORRHAGES, SUBARACHNOID), chemical irritation (chemical MENINGITIS), granulomatous conditions, neoplastic conditions (CARCINOMATOUS MENINGITIS), and other inflammatory conditions may produce this syndrome. (From Joynt, Clinical Neurology, 1994, Ch24, p6)Demyelinating Autoimmune Diseases, CNS: Conditions characterized by loss or dysfunction of myelin (see MYELIN SHEATH) in the brain, spinal cord, or optic nerves secondary to autoimmune mediated processes. This may take the form of a humoral or cellular immune response directed toward myelin or OLIGODENDROGLIA associated autoantigens.Myenteric Plexus: One of two ganglionated neural networks which together form the ENTERIC NERVOUS SYSTEM. The myenteric (Auerbach's) plexus is located between the longitudinal and circular muscle layers of the gut. Its neurons project to the circular muscle, to other myenteric ganglia, to submucosal ganglia, or directly to the epithelium, and play an important role in regulating and patterning gut motility. (From FASEB J 1989;3:127-38)Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or "seizure disorder."Ependyma: A thin membrane that lines the CEREBRAL VENTRICLES and the central canal of the SPINAL CORD.Genes, Insect: The functional hereditary units of INSECTS.Fluorescent Antibody Technique: Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.Sympathectomy: The removal or interruption of some part of the sympathetic nervous system for therapeutic or research purposes.Models, Neurological: Theoretical representations that simulate the behavior or activity of the neurological system, processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.Serotonin: A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.Grasshoppers: Plant-eating orthopterans having hindlegs adapted for jumping. There are two main families: Acrididae and Romaleidae. Some of the more common genera are: Melanoplus, the most common grasshopper; Conocephalus, the eastern meadow grasshopper; and Pterophylla, the true katydid.Ganglia, Sympathetic: Ganglia of the sympathetic nervous system including the paravertebral and the prevertebral ganglia. Among these are the sympathetic chain ganglia, the superior, middle, and inferior cervical ganglia, and the aorticorenal, celiac, and stellate ganglia.Polymerase Chain Reaction: In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.Prosencephalon: The anterior of the three primitive cerebral vesicles of the embryonic brain arising from the NEURAL TUBE. It subdivides to form DIENCEPHALON and TELENCEPHALON. (Stedmans Medical Dictionary, 27th ed)Mice, Inbred Strains: Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations, or by parent x offspring matings carried out with certain restrictions. All animals within an inbred strain trace back to a common ancestor in the twentieth generation.Central Nervous System Helminthiasis: Infections of the BRAIN; SPINAL CORD; or MENINGES caused by HELMINTHS (parasitic worms).Ganglia, Sensory: Clusters of neurons in the somatic peripheral nervous system which contain the cell bodies of sensory nerve axons. Sensory ganglia may also have intrinsic interneurons and non-neuronal supporting cells.Caenorhabditis elegans: A species of nematode that is widely used in biological, biochemical, and genetic studies.DNA-Binding Proteins: Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.Coronavirus Infections: Virus diseases caused by the CORONAVIRUS genus. Some specifics include transmissible enteritis of turkeys (ENTERITIS, TRANSMISSIBLE, OF TURKEYS); FELINE INFECTIOUS PERITONITIS; and transmissible gastroenteritis of swine (GASTROENTERITIS, TRANSMISSIBLE, OF SWINE).Neuroaspergillosis: Infections of the nervous system caused by fungi of the genus ASPERGILLUS, most commonly ASPERGILLUS FUMIGATUS. Aspergillus infections may occur in immunocompetent hosts, but are more prevalent in individuals with IMMUNOLOGIC DEFICIENCY SYNDROMES. The organism may spread to the nervous system from focal infections in the lung, mastoid region, sinuses, inner ear, bones, eyes, gastrointestinal tract, and heart. Sinus infections may be locally invasive and enter the intracranial compartment, producing MENINGITIS, FUNGAL; cranial neuropathies; and abscesses in the frontal lobes of the brain. (From Joynt, Clinical Neurology, 1998, Ch 27, pp62-3)Glutamic Acid: A non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM.Protein Isoforms: Different forms of a protein that may be produced from different GENES, or from the same gene by ALTERNATIVE SPLICING.Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.Neurosecretory Systems: A system of NEURONS that has the specialized function to produce and secrete HORMONES, and that constitutes, in whole or in part, an ENDOCRINE SYSTEM or organ.Myelin Proteolipid Protein: A myelin protein that is the major component of the organic solvent extractable lipoprotein complexes of whole brain. It has been the subject of much study because of its unusual physical properties. It remains soluble in chloroform even after essentially all of its bound lipids have been removed. (From Siegel et al., Basic Neurochemistry, 4th ed, p122)Mice, Mutant Strains: Mice bearing mutant genes which are phenotypically expressed in the animals.Brain Abscess: A circumscribed collection of purulent exudate in the brain, due to bacterial and other infections. The majority are caused by spread of infected material from a focus of suppuration elsewhere in the body, notably the PARANASAL SINUSES, middle ear (see EAR, MIDDLE); HEART (see also ENDOCARDITIS, BACTERIAL), and LUNG. Penetrating CRANIOCEREBRAL TRAUMA and NEUROSURGICAL PROCEDURES may also be associated with this condition. Clinical manifestations include HEADACHE; SEIZURES; focal neurologic deficits; and alterations of consciousness. (Adams et al., Principles of Neurology, 6th ed, pp712-6)Injections, Spinal: Introduction of therapeutic agents into the spinal region using a needle and syringe.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Neurotoxicity Syndromes: Neurologic disorders caused by exposure to toxic substances through ingestion, injection, cutaneous application, or other method. This includes conditions caused by biologic, chemical, and pharmaceutical agents.Morphogenesis: The development of anatomical structures to create the form of a single- or multi-cell organism. Morphogenesis provides form changes of a part, parts, or the whole organism.Cell Lineage: The developmental history of specific differentiated cell types as traced back to the original STEM CELLS in the embryo.Vertebrates: Animals having a vertebral column, members of the phylum Chordata, subphylum Craniata comprising mammals, birds, reptiles, amphibians, and fishes.Electrophysiology: The study of the generation and behavior of electrical charges in living organisms particularly the nervous system and the effects of electricity on living organisms.Autonomic Pathways: Nerves and plexuses of the autonomic nervous system. The central nervous system structures which regulate the autonomic nervous system are not included.Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.Choroid Plexus: A villous structure of tangled masses of BLOOD VESSELS contained within the third, lateral, and fourth ventricles of the BRAIN. It regulates part of the production and composition of CEREBROSPINAL FLUID.Growth Cones: Bulbous enlargement of the growing tip of nerve axons and dendrites. They are crucial to neuronal development because of their pathfinding ability and their role in synaptogenesis.Analysis of Variance: A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

*  Central Nervous System (CNS) Therapeutics - Global Strategic Business Report... ( DUBLIN Novembe
Central Nervous System CNS Therapeutics - Global Strategic Business Report. ... Central Nervous System CNS Therapeutics - Global Strategic ... Breaking Medicine News 10 mins : Health News:Following Recent Tragedy at Oregon School, Slide To Safety, Developer of Patented 6 Second Rapid Evacuation Slide, Is Calling For Federal Government To Act 2 Health News:Abington – Jefferson Health’s Dental Care Access Program Serves Over 100 Local Residents 2 Health News:Abington – Jefferson Health’s Dental Care Access Program Serves Over 100 Local Residents 3 Health News:Registration Is Now Open for the 33rd Annual Dallas Rhinoplasty Symposium 2 Health News:Registration Is Now Open for the 33rd Annual Dallas Rhinoplasty Symposium 3 Health News:Moore Insurance Continues Community Enrichment Program by Fundraising for the Lone Survivor Foundation in Support of Local Veterans and Their Families 2 Health News:Moore Insurance Continues Community Enrichment Program by Fundraising for the Lone Survivor Foundation in Support of...
http://bio-medicine.org/medicine-technology-1/Central-Nervous-System--28CNS-29-Therapeutics---Global-Strategic-Business-Report-2013-2018-37133-1/
*  .. Tag Archives: regulatory .. Wheel weight particles a small source of lead, study says; national
Lead can damage the nervous system, … Continue reading →. Posted ... Weight Initiative , nervous system , New Jersey , particles , phase ... , reproductive system , residue , rims , roadways , sky , ... .. Wheel weight particles a small source of lead, study says; national...
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*  Organic Flax
fundamental to the nervous system as they insulate each nerve ... these good fats. A nervous system deficient in omega-3 s is as ... Flax Oil vs Fish Oil. Nicole Sundene. No comments:. Trans-fatty acids are also implicated in high cholesterol and associated diseases and should be avoided sources include partially hydrogenated oils and margarine. Omega 3 Essential Fatty Acids: cold-water fish such as salmon, tuna, mackerel, and herring are excellent sources. Flax seeds and flax seed oil, and walnuts are good plant sources of essential fatty acids. They are excellent sources of essential fatty acids. Nicole Sundene. No comments:. Nicole Sundene. No comments:. Tips About Flax Oil. Nicole Sundene. To maintain overall health, it is a good idea to keep the dietary intake of omega-3 and omega-6 fatty acids in balance. This means consuming approximately 10 times more omega-6 than omega-3 fatty acids. To achieve more of a healthy balance select nutrient-dense, whole-foods high in omega 3 fats. When substituted for ...
http://organicflaxseeds.blogspot.com/
*  Microbiology Society Journals | Prions spread via the autonomic nervous system from the gut to the c
via the autonomic nervous system from the gut to the central nervous system in cattle incubating bovine ... Journal of Systematic and Evolutionary Microbiology. ... Microbiology Society Journals. Prions spread via the autonomic nervous system from the gut to the central nervous system in cattle incubating bovine spongiform encephalopathy. Microbiology Society. Microbiology Society. Journals. Microbiology Journal of General Virology Journal of Medical Microbiology JMM Case Reports Microbial Genomics NEW International Journal of Systematic and Evolutionary Microbiology. EVENT EVENTLOG PORTALID sgm /PORTALID SESSIONID 238g8dfs8qm23.x-sgm-live-03 /SESSIONID USERAGENT CCBot/2.0 http://commoncrawl.org/faq/ /USERAGENT IDENTITYID guest /IDENTITYID IDENTITY LIST guest /IDENTITY LIST IPADDRESS 23.22.148.121 /IPADDRESS EVENTTYPE PERSONALISATION /EVENTTYPE CREATEDON 1443988802375 /CREATEDON /EVENTLOG EVENTLOGPROPERTY ITEM ID http://sgm.metastore.ingenta.com/content/journal/jgv/10.1099/vir.0.82186-0 /ITEM ID TYPE favo...
http://jgv.microbiologyresearch.org/content/journal/jgv/10.1099/vir.0.82186-0
*  Neurodevelopmental Program | Portland Neurodevelopmental Program | Child Development & Rehabilitatio
stemming from nervous system damage or dysfunction. ... brain or central nervous system which can affect emotion, ... Neurodevelopmental Program. Portland Neurodevelopmental Program. Child Development & Rehabilitation Center. OHSU. Child Development & Rehabilitation Center. Search OHSU. Search Section. Search all of OHSU Search CDRC. Search Text. Search. About CDRC. Clinics Programs. Portland Programs. Eugene Programs. Services. Referrals. Directions to CDRC. Contact CDRC OHSU Home. Find a Doctor. Donate. Jobs. Directions. Contact. Text Size A A A. OHSU Home. Healthcare. Child Development & Rehabilitation Center. Clinics & Programs. Portland Programs. Neurodevelopmental Program. Portland Neurodevelopmental Program. Portland Neurodevelopmental Program. Services & Treatment. Training. Making a Referral. Contact Us Quick Links. MyChart. Find a Doctor. Find Conditions, Treatments and Clinics. Maps and Directions. Contact OHSU. Neurodevelopmental Program The CDRC Neurodevelopmental Program is a resource for ch...
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*  Rabies - KidsHealth For Kids : Akron Children's Hospital
infection of the nervous system. The nervous system controls ... Rabies - KidsHealth For Kids : Akron Children's Hospital. That's why it's so important for someone who's been bitten by an animal to see a doctor. What Will the Doctor Do. If a rabid animal bites someone, the disease will not develop right away. If there's a chance the person was bitten by a rabid animal, the doctor can give the person several shots to prevent the disease. Protect Yourself From Rabies The best way to protect yourself from getting infected with rabies is to never approach any stray or wild animals. The vet will give them shots so they can't catch rabies and give it to you or any other people or animals. Find out how to stay safe around them in this article for kids. Find out more. Healthcare providers. Patient safety quality. Uniquely Akron Children's. Education: Medical Students. About Akron Children's Akron Children's Hospital is one of the largest pediatric hospitals in the U.S., and ranked among the best children's hospital...
https://akronchildrens.org/cms/kidshealth/5352bd23e4b4e397/index.html
*  Household Products Database - Health and Safety Information on Household Products
Spirits: Central Nervous System, Nose & Throat Irritation -- ... product: Central Nervous System, heart, kidney, respiratory ... Household Products Database - Health and Safety Information on Household Products. Product, Manufacturer etc... Advanced Search. Auto Products Inside the Home Pesticides Landscape/Yard Personal Care Home Maintenance Arts Crafts Pet Care Home Office Commercial / Institutional. Products Names Types of Products Manufacturers Ingredients. Product Category: Home maintenance multipurpose Caulk. Related Items: Products with similar usage in this database. Manufacturer. State: CT. Related Items: Products by this manufacturer. The following information Health Effects, Handling/Disposal, and Ingredients is taken from the product label and/or the Material Safety Data Sheet MSDS prepared by the manufacturer. The National Library of Medicine does not test products nor does it evaluate information from the product label or the MSDS. What is an MSDS. Health Effects. Acute Health Effects: From M...
http://hpd.nlm.nih.gov/cgi-bin/household/brands?tbl=brands&id=15005053
*  Cause & Effect Nervous System Laminated Poster
Cause Effect Nervous System Laminated Poster. Skip to Main ... cause & effect nervous system laminated poster. Enlarge / ... Cause & Effect Nervous System Laminated Poster # 573 0618 ... Cause Effect Nervous System Laminated Poster. Email Sign-Up Close. Sign-Up Receive information about new products and educational opportunities, as well as, exclusive offers only available to subscribers. Chiropractic Equipment and Supplies. Call 1.800.747.3488 Order Tracking Customer Service Blog Send Feedback. Sign Up. Shopping Cart 0 Items. Largest Selection of Equipment Supplies. Item Added to Cart Close. Analgesics. Anatomical Charts & Models. Anatomical Charts & Posters. Skeleton & Spine Models 52. Chiropractic Tables. Office Supplies/Equipment. Reconditioned Tables. Sports Chiropractic. New Items. Email Print. anatomical charts & models. anatomical charts & posters. cause & effect nervous system laminated poster. Zoom zoom reset. Cause & Effect Nervous System Laminated Poster # 573 0618 Reviews. Price:. Email:...
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*  Man o' Law: OMG! The humanity
this to the central nervous system needs to be followed up,'' said ... major central nervous system uses with it.''. Botulism ... Man o' Law: OMG. The humanity. Man o' Law. Wednesday, April 2, 2008. OMG. The humanity. Botox May Move From Face to Brain, Study in Rats Says By Elizabeth Lopatto. Bloomberg -- Botulinum neurotoxin type A, sold as Allergan Inc. 's Botox remedy for wrinkles, can move from its injection site to the brain, a study shows. Scientists injected rats' whisker muscles with botulism toxin. Tests of the rodents' brain tissue found that botulism had been transported to the brain stems, the researchers said in the Journal of Neuroscience published April 2. Food and Drug Administration is investigating whether patients contracted botulism, a muscle-weakening illness, from Botox and Myobloc, a product from Solstice Neurosciences Inc. Myobloc is botulinum neurotoxin type B, a different type of botulinum than studied, said Edgar Salazar-Grueso, chief medical officer of Solstice Neurosciences, i...
http://manolaw.blogspot.com/2008/04/omg-humanity.html
*  Oxytocin Inhalant Helps Chronic Headache - Hug the Monkey
of the central nervous system. According to the company, ... nerves and central nervous system, allowing direct access to pain ... Oxytocin Inhalant Helps Chronic Headache - Hug the Monkey. Hug the Monkey. Oxytocin Inhalant Helps Chronic Headache May 26, 2010 Trigemina announced the results of a small clinical trial of intranasal oxytocin for headache. Twenty-five patients with chronic daily headache who didn't get relief from any available remedies received either oxytocin or a placebo. While 47 percent of people treated with oxytocin reported at least a 50 percent reduction in pain, only 11 percent of those getting the placebo got relief. According to the press release, Trigemina researchers don't think it's as simple as oxytocin opening up blood vessels in the head. Instead, inhalants seem to be able to deliver medication to the trigeminal nerve and other parts of the central nervous system. exploits a newly discovered pathway that allows for targeting of the trigeminal nerves and central n...
http://hugthemonkey.com/2010/05/oxytocin-inhalant-helps-chronic-headache.html
*  Stem Cells From Whole Adult Bone Marrow Differentiated Into Central Nervous System Cells -- ScienceD
... aily. Your source for the latest research news. Mobile. Follow. Subscribe. Breaking News :. Ancient Ocean Alga Was Pre-Set for Life On Land. Volcanic Eruptions Affect Flow of Major Rivers. Ocean Bacteria: Millions of Tons of Hydrocarbons. How the Brain Recognizes Objects. Chernobyl: The Animals Have Returned. Illegal Trade Puts Cacti On Most Threatened List. World's Largest Atom Smashers: Smallest Droplets. Crucial Hurdle Overcome in Quantum Computing. Your Visual Cortex Is Making Decisions. Anorexia Nervosa and Gut Bacteria Linked: Study. Science News from research organizations. Stem Cells From Whole Adult Bone Marrow Differentiated Into Central Nervous System Cells. Date: December 20, 2002 Source: Cedars-Sinai Medical Center Summary: Researchers at Cedars-Sinai's Maxine Dunitz Neurosurgical Institute have for the first time demonstrated that stem cells from whole adult bone marrow can be differentiated into several types of cells of the central nervous system. Researchers at Cedars-Sinai's Maxine Dunit...
http://sciencedaily.com/releases/2002/12/021220074148.htm
*  AIDS 2012 Abstract - Unique regulatory mechanisms of CNS-derived HIV-1 LTRs associated with latency
... Abstract. Close. Sign In. Back to the session. TUAA0201 - Oral Abstract Session Unique regulatory mechanisms of CNS-derived HIV-1 LTRs associated with latency Presented by Lachlan Gray Australia. L Gray 1,2, D. Cowley 1,3, E. Crespan 1, C. Welsh 1,4, C. Mackenzie 1,5, P. Gorry 1,3,6, S. Wesselingh 1,7, M. Churchill 1,3,4. 1 Burnet Institute, Centre for Virology, Melbourne, Australia, 2 Monash University, Department of Biochemistry and Molecular Biology, Clayton, Australia, 3 Monash University, Department of Medicine, Clayton, Australia, 4 Monash University, Department of Microbiology, Clayton, Australia, 5 Monash University, Department of Immunology, Melbourne, Australia, 6 The University of Melbourne, Department of Microbiology and Immunology, Melbourne, Australia, 7 South Australian Health and Medical Research Institute, Adelaide, Australia. Background: HIV-1 penetrates the central nervous system CNS during early infection, establishing a viral reservoir. While macrophages and microglia represent the s...
http://pag.aids2012.org/Abstracts.aspx?AID=4029
*  NSC402783(CID 345277) - Compound BioActivity Data
NSC402783 CID 345277 - Compound BioActivity Data. BioActivity Data for Compound NSC402783 CID 345277. BioActivity Outcomes: Inactive 64. BioAssay Types: Confirmatory 58. SAR Target summary Data download. Chemical Probe Active Inactive Inconclusive Unspecified. Total Bioassays: 64 Data Row: 64 Total Pages: 4 Display: 20 50 100 Page. Sort:. # Substance Activity BioAssay Target Links Outcome. Type. Value 1. Inactive. NCI human tumor cell line growth inhibition assay. Data for the U251 Central Nervous System cell line. View X Row No. 1 Structure. Substance. SID 473326. CID 345277. Outcome Inactive. BioAssay NCI human tumor cell line growth inhibition assay. Data for the U251 Central Nervous System cell line. AID 59. BioAssay type confirmatory. Target. PubMed. Data Table. 2 Inactive. NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. View X Row No. 2 Structure. Substance. SID 473326. CID 345277. Outcome Inactive. BioAssay NCI human tumor cell line growth inhibi...
http://pubchem.ncbi.nlm.nih.gov/assay/assay.cgi?cid=345277
*  Pilot Study Switching Individuals Receiving EFV With Continuing Central Nervous System Toxicity to T
Sponsor: St Stephens Aids Trust Information provided by: St Stephens Aids Trust. Criteria Inclusion Criteria: Documented HIV-1 infection Willing to comply with the protocol requirements Has an HIV-plasma viral load at screening 50 HIV-1 RNA copies/mL Has a CD4 cell count at screening 50 cells/mm3 Has been on a stable ART, with at least 3 licensed agents, one of which being EFV, for at least 12 weeks at screening, and is willing to stay on treatment until baseline Symptomatic toxicity associated with the EFV after at least 12 weeks of therapy If subject is female of childbearing potential, she is using effective birth control methods and is willing to continue practicing these birth control methods during the trial and for at least 30 days after the end of the trial or after last intake of investigational ARV's If the subject is a heterosexually active male, he is using effective birth control methods and is willing to continue practicing these birth control methods during the trial and until 30 days after the...
https://clinicaltrials.gov/show/NCT00792324?order=295
*  'New and Important Player' Advances Understanding of ALS | MDA/ALS Newsmagazine
Researchers have identified developmental abnormalities in immature 'NG2+' nervous system cells in ALS-affected mice that appear to play a role in the ALS disease process. An MDA-supported study team has found that "NG2+" stem cells, which mature into a particular type of central nervous system support cell called oligodendrocytes, exhibit a developmental process in mice with a form of ALS that is dramatically different from the process observed in unaffected mice. A population of stem cells called NG2+ cells — which mature into central nervous system support cells called oligodendrocytes — exhibit significant developmental differences in healthy mice compared to mice with a disease resembling human ALS amyotrophic lateral sclerosis, or Lou Gehrig's disease. "These cells contribute in a very large way to metabolic survival of the motor neurons, and in as-yet-unpublished studies, we've shown this process is severely disturbed in ALS." Motor neurons are muscle-controlling nerve cells in the brain and spinal cor...
http://alsn.mda.org/news/new-and-important-player-advances-understanding-als
*  [Histonet] Question: MHC Class II Immunofluorscent Staining on CNS tissue.
question mhc class ii immunofluorscent staining on cns tissue question mhc class ii immunofluorscent staining on cns tissue from vin penaflor hi i am currently having an issue with trying to stain mhc class ii iab af clone on mouse brain tissue for confocal microscopy immunofluorescence i have been trying to use bd pharmingens biotinylated anti mouse i ab coupled with a secondary molecular probes streptavidin so far i have not been able to get the iab staining to work i get completely no staining i am curious if anyone has a successful protocol with conditions that would produce a very bright staining on confocal microscopy with minimal background for this antibody any help would be greatly appreciated i have tried different perfusion techniques freezing techniques fixations wash steps and dilutions of the antibody and so far no luck if anyone has conditions or a protocol that works well with this particular antibody on brain or spinal cord tissue i would greatly appreciate any input i have tried using the pr...
http://histosearch.com/histonet/Jun07A/HistonetQuestion.MHCClass.html
*  Ask.com - What's Your Question?
Answers. Please provide rating before submitting your feedback. Please provide feedback before submitting your response. Thanks for the feedback. Frog Organs. Frog Parts. Frog Central Nervous System. Frog Anatomy. Internal Anatomy of Frogs. The frog has a highly developed nervous system that consists of a brain, spinal cord and nerves. Many parts of the frog's brain ... Nervous System of a Frog. www.tutorvista.com/biology/nervous-system-of-a-frog. Frog has a highly developed nervous system and the nervous system of a frog is divisible into. Central nervous system ... What Organ System in Frogs Is the Most Complex. Animals - mom ... animals.mom.me/organ-system-frogs-complex-9418.html. The most complex organ system in frogs is the nervous system. Nervous system of the frog eduMedia. View of a dissection of the nervous system of the frog. Visualization of the nerve signal propagation from the sensory organs to the effector organs. ANATOMY OF THE FROG :: The Nervous System and Sense ... ANATOMY OF THE FROG, T...
http://ask.com/web?qsrc=6&o=102140&oo=102140&l=dir&gc=1&qo=contentPageRelatedSearch&ad=null&q=Nervous System of a Frog
*  Schizophrenia Forum - Print Paper
Comments on News and Primary Papers Comment by: Bryan Roth, SRF Advisor Submitted 15 July 2012 Posted 16 July 2012 I recommend the Primary Papers This is an interesting and important paper which serves as a cautionary reminder regarding the potential activity of allosteric modulators to have "functionally selective" effects on GPCR signaling Urban et al., 2007 ; Allen and Roth, 2011. Although it has been recognized for some time that allosteric modulators of GPCR activity may also have functionally selective actions Sheffler and Conn, 2008 in vitro, it was unknown if these effects of signaling bias were therapeutically relevant. Abstract View all comments by Bryan Roth. Comment by: Rick Neubig Submitted 19 July 2012 Posted 20 July 2012 This is a very useful paper, but it is worth pointing out that there is really no evidence for "ligand bias" or "functional selectivity" of these compounds. Comment by: Bryan Roth, SRF Advisor Submitted 1 August 2012 Posted 1 August 2012 Regarding the comment by Rick Neubig: wh...
http://schizophreniaforum.org/pap/annotationprint.asp?powID=161766
*  Category:Nervous system neoplasia
category nervous system neoplasia category nervous system neoplasia category types of neoplasia category neurological disorders by disease category...
https://en.wikipedia.org/wiki/Category:Nervous_system_neoplasia
*  Nervous System a system based on the ...
http://bio.net/bionet/mm/neur-sci/1997-July/029082.html
*  Study Reveals Patterns of Gene Activity in the Mouse Nervous System : National Institute of Neurolo
... gical Disorders and Stroke NINDS. Disorders A - Z. News From NINDS. Study Reveals Patterns of Gene Activity in the Mouse Nervous System. Follow NINDSnews For release: Wednesday, October 29, 2003 The first published data from a government-funded project provide remarkable new insights into where specific genes are active in the mouse nervous system during development and adulthood. Information from this project will advance researchers' understanding of how particular genes function in the brain and spinal cord, leading to insights about how the nervous system works. Data from the project, called the Gene Expression Nervous System Atlas, or GENSAT, are reported in the October 30, 2003, issue of Nature.* GENSAT is one of the first large-scale efforts to look at where specific genes are expressed, or translated into proteins, in the brain and spinal cord. The project is funded by the NIH's National Institute of Neurological Disorders and Stroke NINDS. Heintz on the project. Heintz and his colleagues use tran...
http://ninds.nih.gov/news_and_events/news_articles/pressrelease_gensat_102903.htm
*  2011 ICD-9-CM Diagnosis Code 997.00 : Nervous system complication unspecified
... Home > 2011 ICD-9-CM Diagnosis Codes > Injury And Poisoning 800-999 > Complications Of Surgical And Medical Care, Not Elsewhere Classified 996-999 > Complications affecting specified body system not elsewhere classified 997-. 2011 ICD-9-CM Diagnosis Code 997.00. For claims with a date of service on or after October 1, 2015, use an equivalent ICD-10-CM code or codes. More recent version s of ICD-9-CM 997.00 : 2012 2013 2014 2015. Convert to ICD-10-CM : 997.00 converts approximately to: 2015/16 ICD-10-CM G97.81 Other intraoperative complications of nervous system. Disease Synonyms Central nervous system complication Central nervous system complications of care Intraoperative CNS central nervous system complication Intraoperative CNS complication Intraoperative complication of central nervous system Peripheral nerve complication, after hernia repair Peripheral nerve disorder associated with repair of hernia Postprocedural peripheral nerve complication, following hernia repair. ICD-9-CM Volume 2 Index entrie...
http://icd9data.com/2011/Volume1/800-999/996-999/997/997.00.htm
*  ICD-9-CM Diagnosis Codes 668.* : Complications of the administration of anesthetic or othe
668.00 Pulmonary complications of anesthesia or other sedation in labor and delivery, unspecified as to episode of care or not applicable convert 668.00 to ICD-10-CM. 668.01 Pulmonary complications of anesthesia or other sedation in labor and delivery, delivered, with or without mention of antepartum condition convert 668.01 to ICD-10-CM. 668.10 Cardiac complications of anesthesia or other sedation in labor and delivery, unspecified as to episode of care or not applicable convert 668.10 to ICD-10-CM. 668.11 Cardiac complications of anesthesia or other sedation in labor and delivery, delivered, with or without mention of antepartum condition convert 668.11 to ICD-10-CM. 668.20 Central nervous system complications of anesthesia or other sedation in labor and delivery, unspecified as to episode of care or not applicable convert 668.20 to ICD-10-CM. 668.21 Central nervous system complications of anesthesia or other sedation in labor and delivery, delivered, with or without mention of antepartum condition convert ...
http://icd9data.com/2015/Volume1/630-679/660-669/668/default.htm
*  Absent seizures??? - Brain & Nervous System Disorders Message Board - HealthBoards
Absent seizures??. - Brain Nervous System Disorders Message Board - HealthBoards. health boards health message boards. Message Boards. Posting Policy. New Posts. Advanced Search. Search Blogs. Register FAQ Posting Policy Today's Posts Mark Boards Read Advanced Search Find A Board Site Map. Brain Nervous System Disorders Message Board. HealthBoards. Brain Nervous System. Brain Nervous System Disorders > Absent seizures??. Subscribe To Brain Nervous System Disorders. LinkBack Thread Tools Search this Thread. Absent seizures??. Join Date: Oct 2011 Location: Florida Posts: 17. Re: Absent seizures??. Similar Threads. Thread Thread Starter Board Replies Last Post. Cause of seizures unknown to doctors val058 Brain Nervous System Disorders 7 04-03-2011 08:18 AM. Vagus nerve stimulater for seizures dolejaly Brain Nervous System Disorders 0 03-15-2009 06:55 AM. I started Having Seizures at 24 StressInNewYork Brain Nervous System Disorders 1 04-26-2007 07:47 AM. Seizures?. Darlray2 Brain Nervous System Disorders 3 02-11...
http://healthboards.com/boards/brain-nervous-system-disorders/871067-absent-seizures.html
*  Nervous System Disorders,Nervous System Disease,Nervous System Disorders Treatment
... Body Disorders. Endocrine System Disorders. Hair Disorders. Male Sexual Dysfunction. Nervous System Disorders. Respiratory System Disorders. Urinary System Disorders. Weakness of Heart. General Debility. Weakness of Digestive System. A revolution in Unani system of Medicines by giving them a new shape in capsules and Syrup form....a... Ur products have shown good results in various ailments especially Dabidulward Capsules in gynaecolo... congrats Mohsin bhai and wish u good luck for ur bright future........I also believe in unani medici... Dehlvi Naturals Website contains very organised collection of unani literature & classical unani for... Cardiovascular Disorders Endocrine System Disorders Eye Disorders Gastrointestinal Tract Disorders Gynaecological Disorders Hair Disorders Male Sexual Dysfunction Musculoskeletal Disorders Nervous System Disorders Respiratory System Disorders Skin Disorders Urinary System Disorders Venereal Diseases. Description: The Nervous System is divided into: The Central Nervou...
http://dehlvi.com/disorder-Nervous_System_Disorders-view-22.html
*  Nervous System Disorders | CK-12 Foundation
Nervous System Disorders. CK-12 Foundation meta http-equiv="refresh" content="1; url=/nojavascript/". iframe src="//www.googletagmanager.com/ns.html?id=GTM-WVB47G" height="0" width="0" style="display:none;visibility:hidden" /iframe. Dismiss. See what's new this school year. Donate. Help. Join. Sign In. Search. Help. Donate. Join. Sign In. Nervous System Disorders. Circulation, infection and genetic problems can lead to serious diseases of the nervous system. Biology. Human Biology. Featured Content. READ. Nervous System Disorders. Discusses several nervous system disorders. VIDEO. Jill Bolte Taylor's Stroke of Insight. An interesting video where Neurologist Jill Bolte Taylor undergoes an incredible discovery when she wakes one morning to find herself having a stroke. Practice. Practice questions. CK-12 Content. Community Contributed. All Content. At Grade. All Levels. Basic. At Grade. Advanced. Levels are CK-12's student achievement levels. Basic Students matched to this level have a partial mastery of prereq...
http://ck12.org/biology/Nervous-System-Disorders/?by=community
*  ICD-9-CM Diagnosis Code 053.1 : Herpes zoster with other nervous system complications
icd cm diagnosis code herpes zoster with other nervous system complications home icd cm diagnosis codes infectious and parasitic diseases viral diseases accompanied by exanthem herpes zoster icd cm diagnosis code herpes zoster with other nervous system complications non billable code there are icd cm codes below that define this diagnosis in greater detail do not use this code on a reimbursement claim icd data com icd cm codes are used in medical billing and coding to describe diseases injuries symptoms and conditions icd cm is one of thousands of icd cm codes used in healthcare although icd cm and cpt codes are largely numeric they differ in that cpt codes describe medical procedures and services can t find a code start at the root of icd cm check the icd cm index or use the search engine at the top of this page to lookup any code free icd cm codes ...
http://icd9data.com/2015/Volume1/001-139/050-059/053/053.1.htm
*  NPH and pressure headaches - Brain & Nervous System Disorders Message Board - HealthBoards
NPH and pressure headaches - Brain Nervous System Disorders Message Board - HealthBoards. It appears you have not yet Signed Up with our community. To Sign Up for free, please click here.... health boards health message boards. -->. Home. Health Centers. Anxiety More Coming Soon. Message Boards. Posting Policy. New Posts. Advanced Search. FAQ. Find a Board. Drug Talk. Blogs. Sign Up. login. User Name. Password. Remember Me. Register Forget Password. Blogs. Recent Entries. Best Entries. Best Blogs. Blog List. Search Blogs. Register FAQ Posting Policy Today's Posts Mark Boards Read Advanced Search Find A Board Site Map. Brain Nervous System Disorders Message Board. HealthBoards. Brain Nervous System. Brain Nervous System Disorders > NPH and pressure headaches. Subscribe To Brain Nervous System Disorders. LinkBack Thread Tools Search this Thread. 07-09-2012, 08:25 AM # 1. MomHead. Newbie female. Join Date: Jul 2012 Location: Newnan, Georgia USA Posts: 1. NPH and pressure headaches We are aggressively seeking inf...
http://healthboards.com/boards/brain-nervous-system-disorders/908651-nph-pressure-headaches.html
*  feeling unreal and anxious - Brain & Nervous System Disorders Message Board - HealthBoards
feeling unreal and anxious - Brain Nervous System Disorders Message Board - HealthBoards. It appears you have not yet Signed Up with our community. To Sign Up for free, please click here.... health boards health message boards. -->. Home. Health Centers. Anxiety More Coming Soon. Message Boards. Posting Policy. New Posts. Advanced Search. FAQ. Find a Board. Drug Talk. Blogs. Sign Up. login. User Name. Password. Remember Me. Register Forget Password. Blogs. Recent Entries. Best Entries. Best Blogs. Blog List. Search Blogs. Register FAQ Posting Policy Today's Posts Mark Boards Read Advanced Search Find A Board Site Map. Brain Nervous System Disorders Message Board. HealthBoards. Brain Nervous System. Brain Nervous System Disorders > feeling unreal and anxious. Subscribe To Brain Nervous System Disorders. LinkBack Thread Tools Search this Thread. 02-22-2012, 01:32 AM # 1. mchk. Junior Member male. Join Date: Feb 2012 Location: Hong Kong Posts: 12. feeling unreal and anxious 6 years ago, I got a fever and felt un...
http://healthboards.com/boards/brain-nervous-system-disorders/890459-feeling-unreal-anxious.html
*  Overview of Nervous System Disorders - Diseases and Conditions - NewYork-Presbyterian Hospital
... Diseases and Conditions Overview of Nervous System Disorders What is the nervous system. In addition to the brain and spinal cord, principal organs of the nervous system include the following: Eyes Ears Sensory organs of taste Sensory organs of smell Sensory receptors located in the skin, joints, muscles, and other parts of the body What are some disorders of the nervous system. It can be damaged by the following: Trauma Infections Degeneration Structural defects Tumors Blood flow disruption Autoimmune disorders Disorders of the nervous system Disorders of the nervous system may involve the following: Vascular disorders, such as stroke, transient ischemic attack TIA, subarachnoid hemorrhage, subdural hemorrhage and hematoma, and extradural hemorrhage Infections, such as meningitis, encephalitis, polio, and epidural abscess Structural disorders, such as brain or spinal cord injury, Bell's palsy, cervical spondylosis, carpal tunnel syndrome, brain or spinal cord tumors, peripheral neuropathy, and Guillain-...
http://nyp.org/diseasesconditions/showDocument.php?contentTypeId=85&contentId=P00799&subtopicId=Nervous System Disorders&heading=Overview of Nervous System Disorders
*  Regeneron Us Jobs in Basking Ridge, NJ - BusinessWeek
Director Market Access Dupilumab Marketing Atopic Dermatitis US. diseases and central nervous system disorders. • Working closely with the Regeneron US and Sanofi global market access teams to identify opportunities,... 3 days ago from Sanofi. Director US Consumer Marketing Dupilumab Atopic Dermatitis AD. Director US Consumer Marketing, Dupilumab/Atopic Dermatitis AD -75025800-62575 Description At Sanofi US, we are committ ... diseases and central nervous system disorders. 3 days ago from Sanofi. Director Market Development Dupilumab Marketing Atopic Dermatitis US. hybrid organization, including Global/ US Sanofi, and Regeneron Alliance Partners to accomplish transversal... 3 days ago from Sanofi. Director, Market Access, Dupilumab Marketing Atopic Dermatitis - US. diseases and central nervous system disorders. • Working closely with the Regeneron US and Sanofi global market access teams to identify opportunities,... Director Market Access Dupilumab Marketing Atopic Dermatitis US. Sanofi Genzyme - Bridgewater...
http://jobs.businessweek.com/a/all-jobs/list/q-Regeneron US/l-Basking Ridge, NJ
*  Nervous System Diseases
... Spinal Disease. Multiple Sclerosis. Search / Site Map. Share This Site. Nervous System Diseases. Whether you or a loved one has recently been diagnosed with a neurological disease or you are just looking to learn more about neurology and neurosurgery, this site is an introduction to both the diseases that afflict the nervous system as well as the types of procedures and testing that these pathologies often require. Share Your Story Have you or a loved one suffered from a nervous system disease. Share your story with our readers here. Search This Site:. Nervous System Diseases - New Articles Here are new pages and articles which have been added to Nervous System Diseases recently. Learn about the various forms of stroke here. Learn more about epilepsy, its causes and its forms here. This page contains information about various types of tumors of the central nervous system. Learn more about the different forms of this nervous system disease here. Multiple Sclerosis Multiple Sclerosis MS is a diseases of th...
http://nervous-system-diseases.com/
*  Dizzy / Pressure on Top of my Head! HELP! - Brain & Nervous System Disorders Message Board - Health
Dizzy / Pressure on Top of my Head. - Brain Nervous System Disorders Message Board - HealthBoards. health boards health message boards. Message Boards. Posting Policy. New Posts. Advanced Search. Search Blogs. Register FAQ Posting Policy Today's Posts Mark Boards Read Advanced Search Find A Board Site Map. Brain Nervous System Disorders Message Board. HealthBoards. Brain Nervous System. Brain Nervous System Disorders > Dizzy / Pressure on Top of my Head. Subscribe To Brain Nervous System Disorders. LinkBack Thread Tools Search this Thread. 11-02-2004, 02:36 PM # 1. Dizzy / Pressure on Top of my Head. For the last week i have been feeling a pressure on top of my head, like a tingling, or like someone pushing down on my head, I dont get headaches and think im a pretty healthy 31yr old guy. Re: Dizzy / Pressure on Top of my Head. you could be describing high blood pressure. Join Date: Aug 2004 Posts: 1,477. Re: Dizzy / Pressure on Top of my Head. Anyway to spare you all the details of my health issues please che...
http://healthboards.com/boards/brain-nervous-system-disorders/221450-dizzy-pressure-top-my-head-help.html
*  Health Library Overview of Nervous System Disorders Visión General de los Trastornos del Sistem
Cancer Services Cardiovascular Services Diagnostic Imaging Emergency Services Neurosurgery Orthopaedics Rehabilitation Services Sleep Care Stroke Care Weight Loss Women's Services Wound Care Center. View all our services > Health Care Specialties Cancer Services Neurosurgery Stroke Care. Cardiovascular Services Orthopaedics Weight Loss. Maps Directions Medical Services. Maps Directions Medical Services. Maps Directions Medical Services. Maps Directions Medical Services. Maps Directions Medical Services. Maps Directions Medical Services. Maps Directions Medical Services. Maps Directions Medical Services. Maps Directions Medical Services. Home Page - Nervous System Disorders. The branch of medicine that manages nervous system disorders is called neurology. The medical doctors who treat nervous system disorders are called neurologists. The branch of medicine that provides surgical intervention for nervous system disorders is called neurosurgery, or neurological surgery. The branch of medicine that provides rehab...
http://bayhealth.org/health-library/health-library-home?type=2&parm1=p00799&parm2=85&doc=true
*  Nervous system disorders - Psychology Wiki
... Wikia. Skip to Content Skip to Wiki Navigation Skip to Site Navigation. Search this wikia Search all of Wikia. Psychology Wiki Navigation On the Wiki. Nervous system disorders Revision as of 07:43, April 5, 2009 by Dr Joe Kiff. Nervous system disorders or Neurological disorders are disorders that affect the central nervous system brain, brainstem and cerebellum, the peripheral nervous system peripheral nerves - cranial nerves included, or the autonomic nervous system parts of which are located in both central and peripheral nervous system. Nervous system neoplasms Neuromuscular disorders Peripheral nerve disorders Somatosensory disorders. Convulsions demyelinating diseases of the central nervous system, such as multiple sclerosis, and of the peripheral nervous system, such as Guillain-Barré syndrome and chronic inflammatory demyelinating polyneuropathy CIDP. headache disorders such as migraine, cluster headache and tension headache. Extrapyramidal symptoms Hemianopia Hyperkinesia Infections of the periph...
http://psychology.wikia.com/wiki/Nervous_system_disorders?direction=prev&oldid=141241
*  Phys.org - nervous system disorders
... Home nervous system disorders. News tagged with nervous system disorders. 1 day. Last day. 1 week. 1 month. Last day. 1 week. 1 month. Last day. 1 week. 1 month. Fipronil and imidacloprid reduce honeybee mitochondrial activity. New research published in Environmental Toxicology and Chemistry addresses the effects of two broad-spectrum systemic insecticides, fipornil and imidacloprid, on honeybees. Feb 07, 2014 in Cell & Microbiology. Study suggests antioxidant treatment may help NF1-linked behavioral issues. New research in mouse models suggests that treatment with antioxidants may help reduce behavioral issues linked to the genetic nervous system disorder Neurofibromatosis 1 NF1 and an associated condition called Costello ... Sep 12, 2013 in Cell & Microbiology. Over the last half decade, it has become increasingly clear that the normal gastrointestinal GI bacteria play a variety of very important roles in the biology of human and animals. Dec 19, 2012 in Cell & Microbiology. Phys.org —By analyzing the ...
http://phys.org/tags/nervous system disorders/
*  Could I have a seizure in my sleep? - Brain & Nervous System Disorders Message Board - HealthBoards
Could I have a seizure in my sleep. - Brain Nervous System Disorders Message Board - HealthBoards. health boards health message boards. Message Boards. Posting Policy. Advanced Search. Find a Board. Best Entries. Best Blogs. Search Blogs. Register FAQ Posting Policy Today's Posts Mark Boards Read Advanced Search Find A Board Site Map. Brain Nervous System Disorders Message Board. HealthBoards. Brain Nervous System. Brain Nervous System Disorders > Could I have a seizure in my sleep. Subscribe To Brain Nervous System Disorders. LinkBack Thread Tools Search this Thread. Could I have a seizure in my sleep. I really wouldn't have given this ant attention but about two months ago I was hit by a car where I rolled up on the hood and broke the windshield with my head, then I blacked out but I was told that when I rolled off I hit my head really hard again and that's when I chipped my teeth. After I rolled of I had a seizure for like 5 minutes and was unconscious for 15. Join Date: Dec 2004 Posts: 73. Re: Could I hav...
http://healthboards.com/boards/brain-nervous-system-disorders/957017-could-i-have-seizure-my-sleep.html
*  Brain & Nervous System Disorders Board Index: what is a lesion
Brain Nervous System Disorders Board Index: what is a lesion. health boards health message boards. Message Boards. Posting Policy. Advanced Search. FAQ. Find a Board. Best Entries. Best Blogs. Search Blogs. Register FAQ Posting Policy Today's Posts Mark Boards Read Advanced Search Find A Board Site Map. Message Board. HealthBoards. Board Index. Brain Nervous System Disorders. W > what is a lesion. Brain Nervous System Disorders Board Index Board Index > Brain Nervous System Disorders. What is a brain lesion. Jan 4, 2004. My husband was diagnosed with Acute Disseminated Encephamylitis Disease after they found lesions on his brain. 9 replies What is a brain lesion. Dec 18, 2003. A brain lesion is just a tissue injury. 9 replies What is a brain lesion. Dec 8, 2003. Also remember that there are a lot of benign tumors. 9 replies. What is a brain lesion. Dec 7, 2003. I've just been told that I have a brain lesion on the back of my brain. What is a brain lesion. 9 replies What is a brain lesion. Jan 22, 2004. jb 9 r...
http://index.healthboards.com/braindisorders/what-is-a-lesion/1/
*  numbness in left cheek and lips - Brain & Nervous System Disorders Message Board - HealthBoards
numbness in left cheek and lips - Brain Nervous System Disorders Message Board - HealthBoards. To Sign Up for free, please click here.... health boards health message boards. Anxiety More Coming Soon. Message Boards. Posting Policy. New Posts. Advanced Search. FAQ. Find a Board. Best Entries. Best Blogs. Search Blogs. Register FAQ Posting Policy Today's Posts Mark Boards Read Advanced Search Find A Board Site Map. Brain Nervous System Disorders Message Board. HealthBoards. Brain Nervous System. Brain Nervous System Disorders > numbness in left cheek and lips. Subscribe To Brain Nervous System Disorders. LinkBack Thread Tools Search this Thread. numbness in left cheek and lips been seizure free since my 2nd ones 15 years ago but i have been getting a tinglying and numbness with pain in the side of my head and face left side. so bad that i gave myself full on panic attacks so my DR told me today that its actually migraines heres the discription Migraine sufferers may experience: Numb fingers Numb face Arm numbn...
http://healthboards.com/boards/brain-nervous-system-disorders/882612-numbness-left-cheek-lips.html
*  Healthy guy with scalp & forehead tightness/numbness! - Brain & Nervous System Disorders Message Bo
Healthy guy with scalp forehead tightness/numbness. - Brain Nervous System Disorders Message Board - HealthBoards. It appears you have not yet Signed Up with our community. To Sign Up for free, please click here.... health boards health message boards. -->. Home. Health Centers. Anxiety More Coming Soon. Message Boards. Posting Policy. New Posts. Advanced Search. FAQ. Find a Board. Drug Talk. Blogs. Sign Up. login. User Name. Password. Remember Me. Register Forget Password. Blogs. Recent Entries. Best Entries. Best Blogs. Blog List. Search Blogs. Register FAQ Posting Policy Today's Posts Mark Boards Read Advanced Search Find A Board Site Map. Brain Nervous System Disorders Message Board. HealthBoards. Brain Nervous System. Brain Nervous System Disorders > Healthy guy with scalp forehead tightness/numbness. Subscribe To Brain Nervous System Disorders. LinkBack Thread Tools Search this Thread. 07-17-2007, 06:40 PM # 1. sdaris. Newbie male. Join Date: Jul 2007 Location: New York, NY, USA Posts: 1. Healthy guy wi...
http://healthboards.com/boards/brain-nervous-system-disorders/517268-healthy-guy-scalp-forehead-tightness-numbness.html
*  Brain & Nervous System Disorders Board Index: brain calcium deposit
Brain Nervous System Disorders Board Index: brain calcium deposit. It appears you have not yet Signed Up with our community. To Sign Up for free, please click here.... health boards health message boards. -->. Home. Health Centers. Anxiety More Coming Soon. Message Boards. Posting Policy. New Posts. Advanced Search. FAQ. Find a Board. Drug Talk. Blogs. Sign Up. login. User Name. Password. Remember Me. Register Forget Password. Blogs. Recent Entries. Best Entries. Best Blogs. Blog List. Search Blogs. Register FAQ Posting Policy Today's Posts Mark Boards Read Advanced Search Find A Board Site Map. Message Board. HealthBoards. Board Index. Brain Nervous System Disorders. B > brain calcium deposit. Brain Nervous System Disorders Board Index Board Index > Brain Nervous System Disorders. 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z. Pages: 1 Showing 1 - 4 of 4 for brain calcium deposit. 0.008 seconds. What does it mean if a MRI shows you have spots on your Brain Apr 13, 2009. ... My grandson began having...
http://index.healthboards.com/braindisorders/brain-calcium-deposit/1/
*  Brain & Nervous System Disorders Board Index: ear pain nausea
Brain Nervous System Disorders Board Index: ear pain nausea. health boards health message boards. Message Boards. Search Blogs. Register FAQ Posting Policy Today's Posts Mark Boards Read Advanced Search Find A Board Site Map. Message Board. HealthBoards. Brain Nervous System Disorders. E > ear pain nausea. Brain Nervous System Disorders Board Index Board Index > Brain Nervous System Disorders. Pages: 1 Showing 1 - 20 of 23 for ear pain nausea. They were an dull aching occipital headache on my right side and ear pain on my left. 8 replies Tingling in Scalp, headaches, dizziness, and nausea Oct 1, 2009. 6 replies Does this sound like Chiari Malformation. severe pain in my left ear, pain along the left side of my face and down my neck on that side. 2 replies. Over the past couple of years or so, i've been having this localized head pain at the top of my head, on my left side. 5 replies Ear/head pain and fullness Oct 17, 2003. in left ear. I am still getting the awful headache on that side and inside that ear. 5 ...
http://index.healthboards.com/braindisorders/ear-pain-nausea/1/
*  Brain & Nervous System Disorders Board Index: blackout seizures
Brain Nervous System Disorders Board Index: blackout seizures. It appears you have not yet Signed Up with our community. To Sign Up for free, please click here.... health boards health message boards. Health Centers. Message Boards. Posting Policy. New Posts. Advanced Search. FAQ. Find a Board. Blogs. Password. Register Forget Password. Blogs. Recent Entries. Best Entries. Best Blogs. Search Blogs. Register FAQ Posting Policy Today's Posts Mark Boards Read Advanced Search Find A Board Site Map. Message Board. HealthBoards. Board Index. Brain Nervous System Disorders. B > blackout seizures. Brain Nervous System Disorders Board Index Board Index > Brain Nervous System Disorders. Pages: 1 Showing 1 - 5 of 5 for blackout seizures. Seizures. Jul 3, 2003. The slowing could be due to seizures but no other evidence came up on my EEG. 2 replies What is your prognosis and treatment for pineal cyst Nov 29, 2007. I also had both blackout 's & seizures along with other symptoms. I had a few doctors tell me that the cyst w...
http://index.healthboards.com/braindisorders/blackout-seizures/1/
*  Health Library Overview of Nervous System Disorders in ChildrenDescripción General de los Trast
Cancer Services Cardiovascular Services Diagnostic Imaging Emergency Services Neurosurgery Orthopaedics Rehabilitation Services Sleep Care Stroke Care Weight Loss Women's Services Wound Care Center. View all our services > Health Care Specialties Cancer Services Neurosurgery Stroke Care. Select Specialty Addiction Medicine Allergy Anesthesia Cardiology Cardiothoracic Surgery Colorectal Surgery Critical Care Medicine Dermatology Electrophysiology Emergency Medicine Endocrinology Family Medicine Gastroenterology General Surgery General/Vascular General/Vascular/Thoracic Geriatric Medicine Hematology Hospitalist Infectious Disease Internal Medicine Interventional Cardiology Maternal Fetal Medicine Medical Oncology Neonatology Nephrology Neurology Neuroradiology Neurosurgery Nuclear Medicine OB/GYN Occupational Medicine Ophthalmology Oral Maxillofacial Surgery Orthopedic Surgery Otolaryngology Pain Management Pathology Pediatric Cardiology Pediatric Dentistry Pediatric Neurology Pediatrics Physical Medicine Rehab...
http://bayhealth.org/health-library/health-library-home?type=2&parm1=p02618&parm2=90&doc=true
*  Brain & Nervous System Disorders Board Index: head twitch causes
Brain Nervous System Disorders Board Index: head twitch causes. It appears you have not yet Signed Up with our community. To Sign Up for free, please click here.... health boards health message boards. Health Centers. Message Boards. Posting Policy. New Posts. Advanced Search. FAQ. Find a Board. Blogs. Sign Up. Password. Register Forget Password. Blogs. Recent Entries. Best Entries. Best Blogs. Search Blogs. Register FAQ Posting Policy Today's Posts Mark Boards Read Advanced Search Find A Board Site Map. Message Board. HealthBoards. Board Index. Brain Nervous System Disorders. H > head twitch causes. Brain Nervous System Disorders Board Index Board Index > Brain Nervous System Disorders. Pages: 1 Showing 1 - 6 of 6 for head twitch causes. 0.025 seconds. Head tics and twitching causes Apr 30, 2007. What do you mean when you say twitch. Describe what happens if you can. 3 replies Head tics and twitching causes Apr 26, 2007. what causes ur head to twitch. 3 replies Twitching causes Mar 15, 2007. For the past cou...
http://index.healthboards.com/braindisorders/head-twitch-causes/1/
*  Genetic biomarkers has potential to diagnose psychiatric disorders - RightDiagnosis.com
... HOME SYMPTOMS DISEASES DIAGNOSIS VIDEOS TOOLS COMMUNITY MISDIAGNOSIS DOCTORS HOSPITALS DRUGS. News Genetic biomarkers has potential to diagnose psychiatric disorders. Genetic biomarkers has potential to diagnose psychiatric disorders. Measurement of gene blood biomarkers was used by researchers to diagnose and discriminate between schizophrenia and bipolar disorder and those with no psychological disorder. More research is being done in this area with cancer, central nervous system disorders, cardiovascular disease and arthritis receiving particular attention. Source: summary of medical news story as reported by PR Newswire Related Disease Topics:. Psychiatric disorder Psychological disorder Schizophrenia Bipolar disorder Cancer Central nervous system disorder Cardiovascular disease Arthritis Article Source Details. About: Genetic biomarkers has potential to diagnose psychiatric disorders Date: 19 January 2005 Source: PR Newswire URL: http:/ / biz.yahoo.com/ prnews/ 050119/ to246 1.html Related Medical T...
http://rightdiagnosis.com/news/genetic_biomarkers_has_potential_to_diagnose_psychiatric_disorders.htm
*  www.dirtdoctor.com • View topic - Dryer Sheets
View unanswered posts. View active topics Board index. Natural Organic Blogs. Dryer Sheets. Joined: Sat Mar 08, 2003 9:01 am Posts: 961 Location: Dallas, TX You know if you are one of those sensitive to dryer sheets and fabric softeners. Ethanol: On the EPA’s Hazardous Waste list and can cause central nervous system disorders. Limonene: Suspected Gastrointestinal or Liver Toxicant, Immunotoxicant, Kidney Toxicant, Neurotoxicant, Respiratory Toxicant, and Skin or Sense Organ Toxicant. Camphor: Causes central nervous system disorders. Linalool: A narcotic that causes central nervous system disorders. Some of the symptoms experienced from prolonged exposure to the chemicals in dryer sheets include headaches, nausea, vomiting, dizziness, central nervous system disorders, blood pressure reduction, fatigue, difficulty breathing, skin irritation, difficulty concentrating and remembering, cancer, irritation to skin, mucus membranes and respiratory tract, and liver damage. Natural Organic Blogs. Users browsing this ...
http://dirtdoctor.com/efl/dirtdoctor/root/viewtopic.php?f=36&t=15414
*  Central Nervous System Disorders Therapeutics Market to 2017 - Multiple Sclerosis, Major Depressive
Global Market Drivers and Barriers, 2010-2017 61 Figure 33: CNS Disorder Therapeutic Market, Bipolar Disorder, Treatment Algorithm 63 Figure 34: CNS Disorder Therapeutic Market, Diabetic Neuropathy, Global Revenue Forecast $m , 2002-2017 64 Figure 35: CNS Disorder Therapeutic Market, Diabetic Neuropathy, Revenue by Country $m , 2002-2017 65 Figure 36: CNS Disorder Therapeutic Market, Diabetic Neuropathy, Generic Share in Diabetic Neuropathy Market $m , 2010 and 2017 66 Figure 37: CNS Disorder Therapeutic Market, Diabetic Neuropathy, Annual Cost of Treatment $ , 2002-2017 67 Figure 38: CNS Disorder Therapeutic Market, Diabetic Neuropathy, Global Treatment Usage Pattern Thousand , 2002-2017 68 Figure 39: CNS Disorder Therapeutic Market, Diabetic Neuropathy, Global Market Drivers and Restraints, 2010-2017 70 Figure 40: CNS Disorder Therapeutic Market, Epilepsy, Treatment Algorithm 71 Figure 41: CNS Disorder Therapeutic Market, Epilepsy, Global Revenue Forecast $m , 2002-2017 72 Figure 42: CNS Disorder Therapeuti...
http://bio-medicine.org/medicine-technology-1/Central-Nervous-System-Disorders-Therapeutics-Market-to-2017---Multiple-Sclerosis--Major-Depressive-Disorder-and-Schizophrenia-Accounted-for-Half-the--21408-16/
*  NewYork-Presbyterian/Queens - Home Page - Nervous System Disorders
... 網站地圖 English |. NewYork-Presbyterian/Queens Goes Green. My Medical Records. Paying For Your Care. Emergency Care. HealthOutreach: A Program for Older Adults. About Nursing at NYP/Queens. Video Library. Audio Library. HealthOutreach 讀書會. Nervous System Disorders Topic Index Overview of Nervous System Disorders Anatomy of the Brain Diagnostic Tests for Neurological Disorders Neurological Examination Neurological Disorders Glossary Online Resources. The nervous system is a complex, sophisticated system that regulates and coordinates the body's basic functions and activities. It is made up of two major divisions, including the central nervous system consisting of the brain and spinal cord and the peripheral nervous system consisting of all other neural elements. The central nervous system controls vision, thought, speech, behavior, and movement. The peripheral nervous system relays information to the central nervous system about sensation from the body and the special senses such as vision, taste, and hearin...
http://nyhq.org/diw/Content.asp?PageID=DIW000788&language=Chinese
*  Home Page - Nervous System Disorders
... Conditions Treatments. Adult Health Library. Health Library Explorer. Adult Health Library. Conditions & Treatments. Adult Health Library. Allergy and Asthma. Breast Health. Diabetes. Gynecological Health. Home Health, Hospice, and Elder Care. Men's Health. Mental Health Disorders. Nervous System Disorders. Oral Health. Pregnancy and Childbirth. Prostate Health. Skin Cancer. Women's Health. Pediatric Health Library. Blood Disorders. Child and Adolescent Mental Health. Common Childhood Injuries and Poisonings. Dental and Oral Health. Diabetes Endocrinology. High-Risk Pregnancy. Neurological Disorders. Pregnancy. Test and Procedures. Neurological. Pulmonary. Children Ages 0-2. Children Ages 2-18. Men Ages 18-39. Library Index Click a letter to see a list of conditions beginning with that letter. Topic Index Overview of Nervous System Disorders Anatomy of the Brain Diagnostic Tests for Neurological Disorders Neurological Examination Neurological Disorders. The nervous system is a complex, sophisticated syst...
http://healthlibrary.nebraskamed.com/library/diseasesconditions/adult/85,P00788
*  Nervous System Disorders ( Video ) | Biology | CK-12 Foundation
Nervous System Disorders Video. Biology. CK-12 Foundation meta http-equiv="refresh" content="1; url=/nojavascript/". iframe src="//www.googletagmanager.com/ns.html?id=GTM-WVB47G" height="0" width="0" style="display:none;visibility:hidden" /iframe. Dismiss. See what's new this school year. Donate. Help. Join. Sign In. Dashboard. My Class. Library. Browse. Search. Help. Donate. Join. Sign In. Nervous System Disorders. . Circulation, infection and genetic problems can lead to serious diseases of the nervous system. 0 %. Progress. Practice Nervous System Disorders Practice. Progress. 0% Practice Now. Biology. Human Biology. ... ... All. 12. Read. 1. Video. 3. Activities. 1. Study Aids. 1. Assessments. 2. Web Links. 2. Real World. 2. More. All Modalities. Share to Groups. Add to Library. Share to Groups Details. Resources. Alzheimer's: Is the Cure in the Genes. By 2050, as our population ages, 15 million Americans will suffer from Alzheimer's disease– triple today's number. Researchers at San Francisco's Gladstone...
http://ck12.org/biology/Nervous-System-Disorders/enrichment/Alzheimers:-Is-the-Cure-in-the-Genes/
*  About Acorda Therapies for Cardiovascular and Nervous System Disorders | Acorda.com
About Acorda Therapies for Cardiovascular and Nervous System Disorders. Acorda.com. About Acorda. About Acorda. Message From Our CEO. Company Leadership. Company Leadership. Partnering With Acorda. Grant Program. Scientific Award. Contact Us. Compliance. For Patients. For Patients. Focus On Therapies. Resources. Products & Research. Products & Research. Pipeline. Products. Products. AMPYRA ® dalfampridine. Research & Development. Research & Development. Dalfampridine. Cimaglermin Alfa GGF2. Chondroitinase. Clinical Trials. Investors. Investors. Investor Events. Investor News. Financial Information. Financial Information. Quarterly Reports. Annual Reports. Investor Resources. Investor Resources. Investor Kit. IR Contact. News & Events. News & Events. In the News. Company Events. Careers. Careers. Our Employees. Benefits. Job Openings. Application. Privacy Policy. Terms of Use. Site Map. Contact Us. About Acorda Therapeutics. Of the millions of people with nervous system disorders who are in need of new therape...
http://acorda.com/about
*  Congenital & Pediatric Hand Surgery
Congenital Pediatric Hand Surgery. Specialties & Services Specialties & Services Deciding on Care. Specialty Centers & Programs. Quick Links Give to Children's. Specialties & Services. Specialties & Services. Specialty Centers & Programs. Specialty Centers & Programs. Pediatric Surgery. Plastic & Craniofacial Surgery. When your patients suffer a traumatic hand or wrist injury, chances are that they are being treated by the Congenital and Pediatric Hand Surgery Service in the Department of Plastic Surgery at Children’s Health℠. Our Congenital and Pediatric Hand Surgery Service accepts referrals for traumatic hand injuries evaluated at outside clinics and hospital emergency departments. Both surgeons are board certified plastic and hand surgeons who specialize in hand and upper extremity care. Our philosophy is to treat every hand condition, whether traumatic or congenital, as an extension of the patient as a whole. What We Treat Sports Injuries Central Nervous System Disorders Providers What We Treat. What We ...
https://childrens.com/specialties-services/specialty-centers-and-programs/plastic-craniofacial-surgery/programs-and-services/hand-peripheral-nerve-surgery-clinic/conditions-and-treatments/congenital-and-pediatric-hand-surgery
*  Home Page - Nervous System Disorders - NewYork-Presbyterian Hospital
... NewYork-Presbyterian. The University Hospital of Columbia and Cornell. Access medical records from your hospital visits online with myNYP.org Find A Doctor. Clinical Services. Health Library. Research and Clinical Trials. For Patients and Visitors. For Professionals. Request an Appointment. Maps & Directions. Important Telephone Numbers. Glossary of Medical Terms. Diseases and Conditions. Enfermedades y Afecciones. Tests and Procedures. More top doctors than any other hospital in the NY Metro area, according to New York Magazine. More top doctors than any hospital in the US. Health Library Topic Index Overview of Nervous System Disorders Anatomy of the Brain Diagnostic Tests for Neurological Disorders Neurological Examination Neurological Disorders The nervous system is a complex, sophisticated system that regulates and coordinates the body's basic functions and activities. It is made up of two major divisions, including the central nervous system consisting of the brain and spinal cord and the periphera...
http://nyp.org/library/showDocument.php?contentTypeId=85&contentId=P00788&subtopicId=Neurology&heading=Home Page - Nervous System Disorders
*  Nervous system disease
... infobox disease name nervous system disease image caption field neurology diseasesdb icd icd g g icd icd icd icdo omim medlineplus emedicinesubj emedicinetopic meshid d nervous system disease refers to a general class of medical condition s affecting the nervous system they can be divided into central nervous system disease in the cns peripheral neuropathy in the pns reference category nervous system...
https://en.wikipedia.org/wiki/Nervous_system_disease
*  Protein holds promise for drug therapy for central nervous system diseases
... UC Davis Health System. Center for Virtual Care. Center for Virtual Care. Protein holds promise for drug therapy for central ... Center for Virtual Care About Us. Protein holds promise for drug therapy for central nervous system diseases. Researchers at UC Davis have identified previously unrecognized properties of a naturally occurring protein, finding that it enhances brain cell formation and survival and helps regenerate the protective covering around nerve cells, making it a "strong candidate" for drug development for people with diseases such as multiple sclerosis. "That makes PEDF a strong drug-therapy candidate, because it appears to encourage the regeneration of a type of brain cell called oligodendocyte and is able to repair the damage caused by demyelinative diseases, including MS." Pleasure and his colleagues identified PEDF's functions on the adult central nervous system under both normal and pathological conditions in mouse-model research. "What's unique about our findings is that we demonst...
http://ucdmc.ucdavis.edu/publish/news/cvc/6985
*  gms | 77. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Ha
Jahresversammlung der Deutschen Gesellschaft f r Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e. V Application of Auditory Brainstem and Cognitive Responses in Differential Diagnosis of Central Nervous System Diseases. Jahresversammlung der Deutschen Gesellschaft f r Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e. V Deutsche Gesellschaft f r Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e. Application of Auditory Brainstem and Cognitive Responses in Differential Diagnosis of Central Nervous System Diseases Meeting Abstract. The greater the frequency of the stimuli the most valuable changes of the characteristics of the BAEP could be found. We performed a systematic series of measurements in order to specify how the values of latencies and amplitudes change at the stimulus rates above 10 Hz in case of healthy patients. And other hand what differences could be found between the healthy and the patients suffered from central nervous system diseases in the same measuring circumstances. We r...
http://egms.de/static/de/meetings/hno2006/06hno011.shtml
*  .. .. Health Library .. Neurological Disorders in the Newborn .. Centers, Programs & Services .. R
U of U Health Care. Find a Doctor. Services. Locations. University Hospital. Clinical Trials. U of U Health Sciences. U of U Health Care. U of U Health Sciences. Search. Search. Find a Doctor. Services. Locations. University Hospital. Clinical Trials. Health Care Home / Health Information / Related Content /. Health Library. Neurological Disorders in the Newborn. There are several neurological disorders affecting newborns that require clinical care by a doctor or other health care professional. Listed in the directory below are some, for which we have provided a brief overview. Centers, Programs Services. Clinical Neurosciences Center. Diseases and Conditions. Diagnostic Tests for Neurological Disorders. Home Page - Nervous System Disorders. Neurological Conditions. Neurological Disorders. Online Resources - Nervous System Disorders. Overview of Nervous System Disorders. Topic Index - Nervous System Disorders. Neurological Rehabilitation. Rehabilitation for Neurological Disorders. Vision, Hearing ...
http://healthcare.utah.edu/healthlibrary/related/doc.php?type=90&id=P02615
*  .. The IPOs taking the 'ice bucket challenge' .. Markets .. Related News .. Biotech .. Tech ..
But companies are part of the movement, too, in helping to cure central nervous system diseases. Several new companies are in the movement, too, in a somewhat tangential way by working on treatments for the central nervous system diseases in the same broad classification as amyotrophic lateral sclerosis. There are six companies, including Auspex Pharmaceuticals ASPX, Minerva Neurosciences NERV and Adamas Pharmaceuticals ADMS, that have either recently started trading or have filed plans for initial public offerings and are working on treatments for central nervous system diseases, says Renaissance Capital. None of these address amyotrophic lateral sclerosis per se, but they’re all developing treatments to end other central nervous system diseases. Such deals are a big deal on Wall Street since biotech continues to be the engine pushing the initial public offering machine. One of the six companies in the IPO pipeline expected to address central nervous system diseases could be the biggest biotech deal of the ...
http://americasmarkets.usatoday.com/2014/08/27/the-ipos-taking-the-ice-bucket-challenge/
*  Non-Infectious Reproductive System Disorders ( Read ) | Life Science | CK-12 Foundation
Non-Infectious Reproductive System Disorders Read. Non-Infectious Reproductive System Disorders. Practice Non-Infectious Reproductive System Disorders Practice. Resources. Non-Infectious Reproductive System Disorders. Disorders in Males Most common disorders of the male reproductive system involve the testes. For example, injuries to the testes are very common. Another disorder of the testes is cancer. Cancer of the testes is most common in males aged 15 to 35. If found early, cancer of the testes usually can be easily cured with surgery. Disorders in Females Disorders of the female reproductive system may affect the vagina, uterus, or ovaries. One of the most common disorders is vaginitis. This is redness and itching of the vagina. Another possible cause of vaginitis is a yeast infection. Yeast normally grow in the vagina. A common disorder of the ovaries is an ovarian cyst. A cyst is a sac filled with fluid or other material. An ovarian cyst is usually harmless, but it may cause pain. Very large or painful ...
http://ck12.org/life-science/Non-Infectious-Reproductive-System-Disorders-in-Life-Science/lesson/Non-Infectious-Reproductive-System-Disorders/r22/
*  OTC Case Studies | Page 1
OTC Case Studies. Cardiovascular Health. Cough and Cold. Pain Management. Women's Health. OTC Case Studies. Herbal Supplements for Disease Management and Prevention September 2015 Specialty Pharmacy. Pain Awareness August 2015 Pain Awareness. Self-Care for Digestive Health July 2015 Digestive Health. Self-Care for Women's Health June 2015 Women's Health. OTC Case Studies May 2015. May 2015 Skin & Eye Health. Self-Care for Respiratory Health April 2015 Respiratory Health. Self-Care for Central Nervous System Disorders March 2015 Central Nervous System. Herbal Supplements for Autoimmune Conditions February 2015 Autoimmune Disorders. Self-Care for the Aging Population January 2015 The Aging Population. Herbal Supplements for Cardiovascular Diseases December 2014 Heart Health. Self-Care for Cough and Cold November 2014 Cough & Cold. Self-Care for Diabetes October 2014 Diabetes. Self-Care for Oncology Patients September 2014 Oncology. Self-Care for Pain Awareness August 2014 Pain Awareness. Self-Care for Digestive...
http://pharmacytimes.com/publications/issue/departments/otc-case-studies/P-1
*  BioSpace - Forest News, Search Jobs, Events
... Post Jobs. Search Life Sciences Jobs. Profile Search. Company Profile. Forest Laboratories, Inc. At Forest Laboratories, we believe in the power of potential. Our products, including Lexapro®, Namenda® and Benicar®, help treat a range of conditions such as depression, anxiety, Alzheimer’s disease and hypertension. For career opportunities on Long Island, New Jersey and NYC please visit: www.frx.com Last Updated: 06-01-2006 Key Statistics. Forest Employees: 4,300 Symbol: FRX. Collaborations Recordati S.p.A Licensing agreement for the development of lercanidipine, a long-acting dihydropyridine calcium channel blocker for the treatment of hypertension. for central nervous system disorders, including Lexapro. KGaA Licensing agreement for the development and marketing in the U.S. of memantine for the treatment of Alzheimer's Disease and neuropathic pain. Licensing agreement for neramexane, a patented novel NMDA receptor antagonist that is being investigated for a broad range of possible indications related ce...
http://biospace.com/company_profile.aspx?CompanyId=3023
*  ACADIA Pharmaceuticals Announces Completion of Enrollment in Phase III Pimavanserin Trial in Parkins
... on s Disease Psychosis. ACADIA Pharmaceuticals Announces Completion of Enrollment in Phase III Pimavanserin Trial in Parkinson s Disease Psychosis. NASDAQ: ACAD, a biopharmaceutical company focused on innovative treatments that address unmet medical needs in neurological and related central nervous system disorders, today announced the completion of enrollment in its ongoing pivotal Phase III trial with pimavanserin in patients with Parkinson’s disease psychosis PDP. About Pimavanserin Pimavanserin is ACADIA’s proprietary small molecule that acts selectively as an antagonist/inverse agonist on serotonin 5-HT 2A receptors and is in Phase III development as a potential first-in-class treatment for Parkinson’s disease psychosis. About ACADIA Pharmaceuticals ACADIA is a biopharmaceutical company focused on innovative treatments that address unmet medical needs in neurological and related central nervous system disorders. ACADIA has a pipeline of product candidates led by pimavanserin, which is in Phase III de...
http://thenumbers.marketplace.org/publicradio/news/read/22181162/acadia_pharmaceuticals_announces_completion_of_enrollment_in_phase_iii_pimavanserin_trial_in_parkinson’s_disease_psychosis
*  Dr Lal PathLabs - Diagnostic Center, Blood test & Health CheckUps
Corporate Health Enquiry. Find a Lab - Click Here Search by Disease Abortions Acid Base Imbalance Acute Phase Reactant AIDS Allergy Anemia Angioedema Arthritis Autoimmune Disorders Bad Obstetric History Benign Malignant Lesions Bone Mineral Metabolism Breast Cancer Cancer CNS Inflammation Trauma Diabetes Diabetes Insipidus Diptheria Disease Association Disorders of Adrenal Gland Disorders of Bone Disorders of Bone Liver Disorders of Bone Marrow Disorders of Central Nervous System Disorders of CNS Disorders of Coagulation Disorders of Complement Pathway Disorders of Endocrine System Disorders of Gastroenterological Tract Disorders of Gastrointestinal System Disorders of Gastrointestinal Tract Disorders of growth Disorders of Heart Muscle Disorders of Hemopoiesis Disorders of Immunity Disorders of Kidney Disorders of Lipid Disorders of Liver Disorders of Liver Kidney Disorders of Muscle Disorders of Nervous System Disorders of Nutrition Disorders of Ovary Disorders of Pancreas Disorders of Pituitary gland Disor...
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*  Search › diseases nervous system viruses | Quizlet
Search diseases nervous system viruses. Quizlet. . Quizlet. . .  Create a Study Set. Log In .  Log In with Google.  Log In with Facebook. Keep me logged in. Forgot password. Forgot password. Sign Up.  Google Sign In Give us Feedback. diseases nervous system viruses.  500+ Study Sets 500+ Sets. Infectious Diseases of the Nervous Systems: Viruses Bird Wk 5. 9 terms Preview . Nervous System Diseases. 10 terms Preview . Nervous System and Disease. 20 terms Preview . Ch.15 Nervous system: diseases disorder from word parts. 25 terms By marypietrowski Teacher. 25 terms Preview . 42 terms Preview . adaptive immunity, vaccination, immune system disorders, urinary and reproductive system diseases, n…. 149 terms Preview . Small Animal diseases - Nervous system. 43 terms Preview . Nervous System Viruses. 38 terms Preview . Basics of Health and Disease- Nervous System Disease and Mental I...
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*  Viral Vectors as Tools to Investigate the Role of Dysregulated Proteins in Nervous System Pathologie
... s: the Case of Acquired Motor Neuropathies - Author Details. InTechOpen. InTech ‚Äö Open Access Publisher Open Access Books & Journals. Author Panel Login. Subjects. Physical Sciences, Engineering and Technology Chemistry Computer and Information Science. Earth and Planetary Sciences Engineering Materials Science Mathematics Nanotechnology and Nanomaterials Physics Robotics Technology. Life Sciences Agricultural and Biological Sciences Biochemistry, Genetics and Molecular Biology Environmental Sciences. Immunology and Microbiology Neuroscience Health Sciences Medicine Pharmacology, Toxicology and Pharmaceutical Science Veterinary Medicine and Science. Social Sciences and Humanities Business, Management and Economics Psychology Social Sciences All Books All Journals. Books. Journals. About Open Access. News. Publish with Us. Medicine » Medical Genetics » Viral Gene Therapy, book edited by Ke Xu, ISBN 978-953-307-539-6, Published: July 20, 2011 under CC BY-NC-SA 3.0 license. The Author s. Chapter 12. Vi...
http://intechopen.com/books/authors/viral-gene-therapy/viral-vectors-as-tools-to-investigate-the-role-of-dysregulated-proteins-in-nervous-system-pathologie
*  Herbs and Supplements for immune system disordersHerbs and Supplements for immune system disorders
 Herbs and Supplements for immune system disorders. Herbs and Supplements for immune system disorders. Emergency Dept: 314-205-6990. Patient Billing: 888-924-9200. Services. Health Tools. Classes & Events. Donate & Volunteer. Physicians & Employees. Careers. Contact Us History Mission Locations & Directions Quality Reports Annual Reports Honors & Awards Community Health Needs Assessment Newsroom Brain & Spine Cancer Heart Maternity Orthopedics Pulmonary Sleep Medicine Urgent Care Women's Services All Services Locations & Directions Find a Physician Tour St. Spirit of Women Health Information & Tools Clinical Trials Health Risk Assessments Employer Programs - Passport to Wellness Classes & Events Spirit of Women Giving Opportunities Volunteer For Physicians Remote Access Medical Residency Information Pharmacy Residency Information Physician CPOE Training. Health Information. Complementary and Alternative Medicine Herbs and Supplements for immune system disorders. Herbs and Supplements for immune system disord...
http://stlukes-stl.com/health-content/medicine/33/002517.htm
*  Nervous System Diseases And Disorders List
... This autoimmune disorder can occur with as much. The symptoms of lupus. Research in Women's Health ORWH and the fatigue and no disease worsening in various organs after one year. Some say that she had lupus when I woke stem cell therapy autoimmune disease up today with hand pain. For years he has type 2 diabetes in Australia as part of the body that leads to poor nutrient absorption. Lupus in men with Lupus have mild or no islet cells have been growing pains, resistance, temper-tantrums, and no known mechanism whereby stress causes an autoimmune disease is by improving your spiritual life. Systemic Lupus Erythematosis SLE, celiac disease. Patients who did not want anyone to help him. Although it is not good for you to get a ratio of 20:1 if they had higher levels of emitted UV radiation, and myocarditis in the body. This autoimmune disorder the doctor with four years of UV radiation intensity showed the same disease. A companion study has major consequences, such as MS, rheumatoid arthritis, asthma, arth...
http://autoimmunediseaseaid.com/nervous-system-diseases-and-disorders-list
*  .. Stem Cell Tech Gets Boost from Academic–Industry Partnership ..
Roche and the Innovative Medicines Initiative IMI launched StemBANCC, a new academic industry partnership that unites ten pharmaceutical companies and 23 academic institutions. Initiated and coordinated by Roche and managed by Oxford University, StemBANCC aims to use human induced pluripotent stem cells as research tools for drug discovery with the goal of using this new technology to develop human disease models and enhance drug development. The aim of StemBANCC is to generate and characterize 1,500 high quality human induced pluripotent stem cell lines derived from 500 patients that can be used by researchers to study a range of diseases including diabetes and dementia," explained Martin Graf, head of the stem cell platform and coordinator of the project. The cell lines will help implement patient models that will facilitate the drug development process thanks to the possibility of reproducing the disease mechanism in vitro. For example, skin cells can only make other skin cells, and liver cells can only ma...
http://genengnews.com/keywordsandtools/print/4/29712/
*  Healthy Viewpoints
Paul H. Resnik, MD. The shingles virus often emerges to affect the face. Painful Shingles There is Help Paul H. Resnik, MD Pain Management Pain Clinic of Northwestern Wisconsin, Eau Claire We have only a vague idea of what shingles is, or the amount of misery that can potentially result when an individual suffers an outbreak. Shingles is caused by the same virus that causes chickenpox, called the Varicella-Zoster virus, or VZV. Most people have chickenpox when they are children and rarely suffer severe complications. The virus runs its course as a childhood disease, and then goes into hiding, in cells that make up the nerves of the nervous system. It may appear as a rash, confined to a fairly well defined painful strip of skin, which follows the path of the nerve. How the virus emerges is quite variable and a rash is not always present. The most common area for shingles to appear is the chest wall. Unrecognized shingles can progress to nervous system complications, including blindness and/or chronic painful n...
http://oakleafmedical.com/hv/2006_win/win2006_shingles.htm
*  Tykerb and Palmar-Plantar Erythrodysaesthesia Syndrome - Suspected Cause - Reports of Side Effects
Reported by a health professional non-physician/pharmacist from Australia on 2012-08-03 Patient: female Reactions: Central Nervous System Lesion, Palmar-Plantar Erythrodysaesthesia Syndrome, Hypoaesthesia, Nail Infection, Diarrhoea, Oral Pain, Skin Lesion, Eye Disorder, Brain Neoplasm Adverse event resulted in: hospitalization Drug s suspected as cause: Tykerb Administration route: Oral Indication: Breast Cancer Metastatic Start date: 2011-10-14 Xeloda Indication: Product Used FOR Unknown Indication Start date: 2011-10-14 Possible Tykerb side effects in. Reported by a health professional non-physician/pharmacist from Australia on 2012-07-05 Patient: female Reactions: Central Nervous System Lesion, Palmar-Plantar Erythrodysaesthesia Syndrome, Hypoaesthesia, Nail Infection, Diarrhoea, Oral Pain, Skin Lesion, Eye Disorder, Brain Neoplasm Drug s suspected as cause: Tykerb Administration route: Oral Indication: Breast Cancer Metastatic Start date: 2011-10-14 Xeloda Indication: Product Used FOR Unknown Indication S...
http://druglib.com/reported-side-effects/tykerb/reaction_palmar-plantar_erythrodysaesthesia_syndrome/
*  Reproductive system disorders
... redirect reproductive system disease...
https://en.wikipedia.org/wiki/Reproductive_system_disorders
*  Category:Demyelinating diseases of CNS
category demyelinating diseases of cns category demyelinating diseases of cns category neurological disorders by disease category category central nervous system disorders category central nervous system...
https://en.wikipedia.org/wiki/Category:Demyelinating_diseases_of_CNS
*  Afluria 2012-2013 intramuscular : Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - We
Afluria 2012-2013 intramuscular : Uses, Side Effects, Interactions, Pictures, Warnings Dosing - WebMD. Taking Medications During Pregnancy. WebMD My Medicine Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more. Sign up to receive WebMD's award-winning content delivered to your inbox. Family Pregnancy. Sign up to receive WebMD's award-winning content delivered to your inbox. Children under 9 years of age may receive a second dose depending on when the first dose was given. List Afluria 2012-2013 intramuscular side effects by likelihood and severity. Before receiving this vaccination, tell your health care professional if you are allergic to it; or to any other vaccines; or if you have any other allergies. Before receiving this vaccine, tell your health care professional your medical history, especially of: any fever, uncontrolled seizures or other nervous system disorder such as encephalopathy, bleeding disorders such as hemophilia, thrombocytopenia, history of Guill...
http://webmd.com/drugs/2/drug-161713/afluria-2012-2013-im/details
*  Fluvirin 2012-2013 (PF) intramuscular : Uses, Side Effects, Interactions, Pictures, Warnings & Dosin
Fluvirin 2012-2013 PF intramuscular : Uses, Side Effects, Interactions, Pictures, Warnings Dosing - WebMD. Taking Medications During Pregnancy. WebMD My Medicine Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more. Sign up to receive WebMD's award-winning content delivered to your inbox. Sign up to receive WebMD's award-winning content delivered to your inbox. Children under 9 years of age may receive a second dose depending on when the first dose was given. List Fluvirin 2012-2013 PF intramuscular side effects by likelihood and severity. Before receiving this vaccination, tell your health care professional if you are allergic to it; or to any other vaccines; or if you have any other allergies. Before you receive this vaccine, tell your health care professional your medical history, especially of: any fever, uncontrolled seizures or other nervous system disorder such as encephalopathy, bleeding disorders such as hemophilia, thrombocytopenia, history of Guillain-Barr...
http://webmd.com/drugs/2/drug-161715/fluvirin-2012-2013-pf-im/details
*  CranioSacral Therapy for Babies & Children (Pregnancy, Birth and Beyond)
CranioSacral Therapy for Babies Children Pregnancy, Birth and Beyond. Pregnancy, Birth and Beyond. Baby products. Breastfeeding products. Midwifery Supplies. Baby Massage. Massage Therapists. Homebirth Stories. Hospital Birth Stories. Pregnancy Stories. Teenage Stories. Twin Birth Stories. VBAC Stories. Waterbirth Stories Book DVD reviews. News in 2010 Our forum. Teenage Pregnancy Teenage Pregnancy Articles. Teenage Pregnancy Links. Teenage Pregnancy Stories. Teenage Pregnancy Support. Labour and Birth. Breastfeeding. Parenting. Twin Videos What To Eat in Pregnancy Midwifery How to become a midwife. CranioSacral Therapy is a light-touch therapy shown to be effective in supporting the central nervous system so that your child’s body can self-correct and heal naturally. By supporting the central nervous system and releasing restrictions throughout the body, CranioSacral Therapy has shown to bring about profound healing. Autism Spectrum and Sensory Processing Disorders Abnormal Muscle Tone Seizures Strabismus, N...
http://pregnancy.com.au/parenting/baby-health/craniosacral-therapy-for-babies-and-children.shtml
*  Go For The Glory Quiz: Persistent Oral Lesions, Nevus or Melanoma?, Altered Mental Status in Middle
... Age, An Itchy, Scaly Rash, Painful Blisters of the Hand. ConsultantLive. ConsultantLive SearchMedica. Topics: Atrial Fibrillation. Cardiovascular Diseases. Diabetes Type 2. HIV AIDS. Nervous System Diseases. Respiratory Diseases. Browse All Topics All Topics Atrial Fibrillation Cardiovascular Diseases COPD Men's Health Diabetes Type 2 Pain HIV AIDS Nervous System Diseases Obesity Respiratory Diseases. MAIN MENU Home Topics Dermatology Cardiovascular Diabetes GI HIV/AIDS Conferences Quizzes Photoclinic Image IQ Pediatrics. Connect to other sites within the UBM Medica Network. ConsultantLive SearchMedica. Topics: Atrial Fibrillation. Cardiovascular Diseases. Diabetes Type 2. HIV AIDS. Nervous System Diseases. Respiratory Diseases. Browse All Topics All Topics Atrial Fibrillation Cardiovascular Diseases COPD Men's Health Diabetes Type 2 Pain HIV AIDS Nervous System Diseases Obesity Respiratory Diseases. Main menu Home. Topics. MAIN MENU Home Topics Dermatology Cardiovascular Diabetes GI HIV/AIDS Conferences...
http://consultantlive.com/skin-diseases/go-glory-quiz-persistent-oral-lesions-nevus-or-melanoma-altered-mental-status-middle-age-itchy-scaly
*  Headache | ConsultantLive
ConsultantLive SearchMedica. Topics: Atrial Fibrillation. Cardiovascular Diseases. Diabetes Type 2. HIV AIDS. Nervous System Diseases. Respiratory Diseases. Browse All Topics All Topics Atrial Fibrillation Cardiovascular Diseases COPD Men's Health Diabetes Type 2 Pain HIV AIDS Nervous System Diseases Obesity Respiratory Diseases. MAIN MENU Home Topics Dermatology Cardiovascular Diabetes GI HIV/AIDS Conferences Quizzes Photoclinic Image IQ Pediatrics. Login or Register Welcome My Account. Connect to other sites within the UBM Medica Network. ConsultantLive SearchMedica. Topics: Atrial Fibrillation. Cardiovascular Diseases. Diabetes Type 2. HIV AIDS. Nervous System Diseases. Respiratory Diseases. Browse All Topics All Topics Atrial Fibrillation Cardiovascular Diseases COPD Men's Health Diabetes Type 2 Pain HIV AIDS Nervous System Diseases Obesity Respiratory Diseases. Topics. MAIN MENU Home Topics Dermatology Cardiovascular Diabetes GI HIV/AIDS Conferences Quizzes Photoclinic Image IQ Pediatrics. Topics ADHD As...
http://consultantlive.com/headache?p_p_id=EXT_4&p_p_action=0&p_p_state=normal&p_p_mode=view&p_p_col_id=column-3&p_p_col_pos=3&p_p_col_count=8&_EXT_4_struts_action=/articles_display/view&_EXT_4_keywords=&_EXT_4_advancedSearch=false&_EXT_4_andOperator=true&cur=51
*  Phosphodiesterase-4 inhibitor
... A 'phosphodiesterase type 4 inhibitor', commonly referred to as a 'PDE4 inhibitor', is a drug used to block the degradative action of phosphodiesterase 4 PDE4 on cyclic adenosine monophosphate cAMP. The PDE4 family of enzymes are the most prevalent PDE in immune cells. They are predominantly responsible for hydrolyzing cAMP within both immune cells and cells in the central nervous system. 1 Therapeutic utility Adverse reactions Examples {{anchor|PDA4 inhibitor}} Mode of action See also References. The prototypical PDE4 inhibitor is rolipram. 6 Consequently, PDE4 inhibitors have been investigated as treatments for a diverse group of different diseases, including central nervous system disorders such as major depressive disorder clinical depression, anxiety disorders, schizophrenia,. PDE4D inhibition, along with PDE4A inhibition also appears to be responsible for the antidepressant effects of PDE4 inhibitors. Similarly PDE4B inhibition appears to be required for the antipsychotic effects of PDE4 inhibitors...
https://en.wikipedia.org/wiki/Phosphodiesterase-4_inhibitor
*  Circulatory System Diseases | CK-12 Foundation
Circulatory System Diseases. CK-12 Foundation meta http-equiv="refresh" content="1; url=/nojavascript/". Help. Help. Circulatory System Diseases. READ. Circulatory System Diseases. An overview of cardiovascular diseases and their risk factors. Practice. Practice questions. CK-12 Content. All Content. At Grade. All Levels. At Grade. Levels are CK-12's student achievement levels. At Grade Proficient Students matched to this level have demonstrated competency over challenging subject matter, including subject matter knowledge, application of such knowledge to real-world situations, and analytical skills appropriate to subject matter. Read. Real World. Read. Circulatory System Diseases. by CK-12. // at grade. An overview of cardiovascular diseases and their risk factors. Twitter. Facebook. Email. 3 Lesson Plan. The Circulatory System. by CK-12. // at grade. "In this activity, students explore the interrelationship of structure and function in the circulatory system." - Teachers' Domain. Twitter. Facebook. Email. ...
http://ck12.org/biology/Circulatory-System-Diseases/
*  Eternal Springs | ConsultantLive
Eternal Springs. ConsultantLive. Skip to main content. Search For... Search. ConsultantLive SearchMedica. Topics: Atrial Fibrillation. Cardiovascular Diseases. COPD. Men s Health. Diabetes Type 2. Pain. HIV AIDS. Nervous System Diseases. Obesity. Respiratory Diseases. Browse All Topics All Topics Atrial Fibrillation Cardiovascular Diseases COPD Men's Health Diabetes Type 2 Pain HIV AIDS Nervous System Diseases Obesity Respiratory Diseases. MAIN MENU Home Topics Dermatology Cardiovascular Diabetes GI HIV/AIDS Conferences Quizzes Photoclinic Image IQ Pediatrics. Welcome Guest. Login or Register Welcome My Account. My Account or Logout. Connect to other sites within the UBM Medica Network. Search For... Search. ConsultantLive SearchMedica. Topics: Atrial Fibrillation. Cardiovascular Diseases. COPD. Men s Health. Diabetes Type 2. Pain. HIV AIDS. Nervous System Diseases. Obesity. Respiratory Diseases. Browse All Topics All Topics Atrial Fibrillation Cardiovascular Diseases COPD Men's Health Diabetes Type 2 Pain HI...
http://consultantlive.com/nervous-system-diseases/eternal-springs
*  USDA Probe Finds Big Holes In US Mad Cow Testing
... Department of Agriculture poor marks in testing cattle for mad cow disease, saying the agency was neglecting to test the majority of cattle most at risk. A draft report was provided by the House of Representatives Government Reform Committee. The report said that despite a much-advertised expanded surveillance program the USDA was not testing adult cattle that died on the farm and had failed to test hundreds of cattle condemned due to possible central nervous system disorder -- a symptom of mad cow disease and many other diseases. A process for obtaining samples from animals that died on the farm has not been developed, the report said. The report also said the USDA failed to test 518 of the 680 cattle condemned at slaughter for central nervous system symptoms between fiscal 2002 and 2004. Those symptoms indicate an animal could be suffering from one of several illnesses, including mad cow disease. Investigators said the department's failure to test these animals raised questions about the credibility of...
http://rense.com/general54/madco.htm
*  Clinical Trials Resource Center - Hepatitis Foundation International
... . News. News Archive. Clinical Trials. Centers for Disease Control and Prevention. National Institutes of Health. AASLD Drug Alerts. Clinical Trials Resource Center. About Research. Trials. NIH Trials. Email Notifications. FDA Approvals. Research Centers Research Headlines. NMT Results. Bookstore. Research Center Profile: CNS Research of RI, Inc. Center Information. Patricia J. Epple, RN, BSN, CCRC, Sr. CRA Research Director and President CNS Research of RI, Inc. P.O. Box 4563 Providence, RI 02906 USA 1-800-707-6013 Ext. 101 1-800-847-4332 fax info@cns-research.com www.cns-research.com Contact Center. Currently Enrolling Trials TTP488-301: Randomized, Double-Blind, Placebo Controlled, Multi-Center Registration Trial to Evaluate the Efficacy and Safety of TTP488 in Patients with Mild Alzheimer's Disease Receiving Acetylcholinesterase Inhibitors and/or Memantine. Therapeutic Areas Neurology. Center Overview CNS Research Inc. was founded in 1997 and is a multi-site PPPN, Private Practice Physician's Network...
http://centerwatch.com/news-resources/research-centers/profile/198/cns-research-of-ri-inc/?mp=HEPFI
*  GEN Podcasts Related To | GEN
GEN Podcasts Related To. GEN. Transitioning from Traditional Assay Formats to HTRF Technology. Linking Phenotypes and Modes of Action Through High-Content Screen Fingerprints. Jobs Report: Data, Business, and Regulatory Savvy Driving New Hiring. FDA Nominee Driven by "Data, Data, Data". More GEN Exclusives ». The Pons Asinorum of Diagnostic Genomics. Transitioning from Traditional Assay Formats to HTRF Technology. Linking Phenotypes and Modes of Action Through High-Content Screen Fingerprints. Jobs Report: Data, Business, and Regulatory Savvy Driving New Hiring. FDA Nominee Driven by "Data, Data, Data". Standardization of High Content Imaging and Informatics. More GEN Exclusives ». MORE GEN. Market & Tech Analysis. Jobs. GEN Exclusives More. Transitioning from Traditional Assay Formats to HTRF Technology Sensitivity of Fluorescence Coupled to Low... GEN Podcasts Related to PsychoGenics to Assess AstraZeneca Candidates for Treating Central Nervous System Disorders DISCOVERY OF A CHEMICAL SIGNATURE IN THE BRAIN...
http://genengnews.com/more/related/gen-podcasts/5/9603/
*  Peptide Therapeutics Market (by Applications, by Route of Administration, and by Marketing Status) -
Peptide Therapeutics Market by Applications, by Route of Administration, and by Marketing Status - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020, Trends, Share, Size Research Report. 866-997-4948 US-Canada Toll Free. Home Latest Report Category Publisher Country Niche Market Articles Press Release Contact. Home. Transparency. Pharmaceutical Peptide Therapeutics Market by Applications, by Route of Administration, and by Marketing Status - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020. Peptide Therapeutics Market by Applications, by Route of Administration, and by Marketing Status - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020. Published By : Transparency. Published Date : Apr 2015. Category : Pharmaceutical. No. of Pages : 104. Description Table of Content Related Reports Check Discount. The global peptide therapeutics market report provides detailed analysis, market size, and forecast for therapeutic peptides a...
http://researchmoz.us/peptide-therapeutics-market-global-industry-analysis-market-size-market-share-and-forecasts-2012-2018-report.html
*  Thalamocortical dysrhythmia
... 'Thalamocortical Dysrhythmia TCD ' is a theoretical framework in which neuroscientists try to explain the positive and negative symptoms induced by neurological disorders like Parkinson's Disease, neurogenic pain, Tinnitus, Epilepsy as well as neuropsychiatric disorders like depression. In TCD, normal thalamocortical resonance is disrupted by changes in the behaviour of neurons in the thalamus. TCD can be treated with neurosurgical methods like the central lateral thalamotomy, which due to its invasiveness is only used on patients that have proven resistant to conventional therapies. Background Evidence Therapy External links. Background. This leads to a switch of the thalamocortical neurons from tonic to burst firing and subsequently entrains thalamic and cortical areas with pathological oscillations at around 5 Hz. Evidence. Evidence for TCD comes from Magnetoencephalography MEG, and Electroencephalography EEG recordings on the scalp as well as local field potential LFP recordings in the patients' thal...
https://en.wikipedia.org/wiki/Thalamocortical_dysrhythmia
*  Abbott Pays Reata $400M in Expanded Antioxidant Inflammation Modulator Deal | GEN News Highlights
Abbott Pays Reata $400M in Expanded Antioxidant Inflammation Modulator Deal. FDA Nominee Driven by "Data, Data, Data". Linking Phenotypes and Modes of Action Through High-Content Screen Fingerprints. Jobs Report: Data, Business, and Regulatory Savvy Driving New Hiring. FDA Nominee Driven by "Data, Data, Data". Linking Phenotypes and Modes of Action Through High-Content Screen Fingerprints. Jobs Report: Data, Business, and Regulatory Savvy Driving New Hiring. Top 10 Pharma Firms of 2015. Market & Tech An... Top 10 Pharma Firms of 2015 Which Traditional Drug Developers Generated the... Linking Phenotypes and Modes of Action Through High-Content Screen Fingerprints The Use of High-Content Screening as... GEN News Highlights More » Dec 12, 2011 Abbott Pays Reata $400M in Expanded Antioxidant Inflammation Modulator Deal Page 1 of 1 Abbott is paying Reata Pharmaceuticals $400 million up front as part of a worldwide collaboration to jointly develop and commercialize the latter s second-generation oral antioxidant in...
http://genengnews.com/gen-news-highlights/abbott-pays-reata-400m-in-expanded-antioxidant-inflammation-modulator-deal/81246056/?kwrd=Bardoxolone Methyl
*  UGA Center for Drug Discovery Faculty
... Center for Drug Discovery "...knowledge belongs to humanity and is the torch which illuminates the world..." Louis Pasteur. Home. Giving to the CDD. Message from the Director. Historical Background. Objectives, Goals, Core Values. Conference Archives. Organizational Chart. Faculty. Staff. Related Programs. Location Map. Contact Us. Faculty: Biography. Shelley Hooks, Ph.D. CDD Associate Director, Associate Professor Pharmaceutical and Biomedical Sciences Address: Pharmacy South Building University of Georgia Athens, GA 30602. Office: Room 338. Phone: 706 542-2189. Email: shooks@uga.edu. Biosketch B.S. Biochemistry Clemson University Clemson, SC 1996. Ph.D. Biochemistry University of Virginia Charlottesville, VA 2000. Post-doctoral Experience Postdoctoral Fellow, University of North Carolina-Chapel Hill, Chapel Hill, NC, 2001-2004 Honors and Awards Awarded individual postdoctoral F32 NRSA grant NIGMS, 2002 Founded and organized UNC Women in Science and Research, 2001-2004 Won oral communication award at th...
http://uga-cdd.org/facultydetail.php?id=20
*  ACADIA Pharmaceuticals Announces Election of Stephen R. Biggar to Its Board of Directors | EON: Enha
ACADIA Pharmaceuticals Announces Election of Stephen R. Biggar to Its Board of Directors. EON: Enhanced Online News. News. Resources. . ACADIA Pharmaceuticals Announces Election of Stephen R. Biggar to Its Board of Directors. January 22, 2013 09:00 AM Eastern Daylight Time SAN DIEGO--. BUSINESS WIRE --ACADIA Pharmaceuticals Inc. NASDAQ: ACAD, a biopharmaceutical company focused on innovative treatments that address unmet medical needs in neurological and related central nervous system disorders, today announced the election of Stephen R. Biggar, M.D., Ph.D., to its board of directors. Dr. Biggar will fill a vacancy on ACADIA’s board and serve as a Class II director. The terms of the Class II directors will expire at the annual meeting of stockholders in 2015. His extensive experience as an investor in a wide range of biotechnology companies together with his medical and scientific training will provide our board with a unique perspective and enhance our collective experience. “This is a particularly exciting ...
http://enhancedonlinenews.com/portal/site/eon/permalink/?ndmViewId=news_view&newsId=20130122005572&newsLang=en&permalinkExtra=ACADIA-Pharmaceuticals-Announces-Election-Stephen-R.-Biggar
*  Baytril Injection - Treating Bacterial Infections in Pets | PetCareRx
Baytril Injection - Treating Bacterial Infections in Pets. PetCareRx Points 0. My PetCareRx Points. Flea Tick. Arthritis Pain. Vitamins Supplements. Prescription Food. Food Nutrition. Vitamins Supplements. Flea Tick. Arthritis Pain. Vitamins Supplements. Prescription Food. Food Nutrition. Vitamins Supplements. Shop By Pet Flea & Tick. Arthritis & Pain. Vitamins & Supplements. Prescription Food. Flea & Tick. Arthritis & Pain. Vitamins & Supplements. Prescription Food. Flea Tick. Food & Nutrition. Arthritis & Joint Pain. Flea & Tick. Food & Nutrition. Arthritis & Joint Pain. Medication guides breed guides product guides. Medication Guides. Using Baytril Injection for Dog and Cat Infections About this Antiinfective Antibiotic that Treats Bacterial Infections in Dogs, Cats, Pigs, Cattle, and Poultry By Team PetCareRx. indications for Baytril Injection Baytril Injection belongs to the category of antiinfectives and is used in the treatment of bacterial diseases of dogs, cats, pigs, cattle and poultry. coli, Salmon...
http://petcarerx.com/medication-guides/using-baytril-injection-for-dog-and-cat-infections/1032
*  StemCells Inc Discontinues Batten Disease Program
These statements include, but are not limited to, statements regarding the prospect of conducting future clinical research in NCL; the potential of the Company's HuCNS-SC cells to treat a broad range of central nervous system disorders; and the future business operations of the Company, including its ability to conduct clinical trials as well as its other research and product development efforts. The Company's actual results may vary materially from those contemplated in such forward-looking statements due to risks and uncertainties to which the Company is subject, including the fact that additional trials will be required to demonstrate the safety and efficacy of the Company's HuCNS-SC cells for the treatment of any disease or disorder; uncertainty as to whether the FDA or other applicable regulatory agencies will permit the Company to continue clinical testing in spinal cord injury, PMD or in future clinical trials of proposed therapies for other diseases or conditions given the novel and unproven nature of...
http://biospace.com/News/stemcells-inc-discontinues-batten-disease-program/216596
*  BioSpace - Merck & Co. News, Search Jobs, Events
... Post Jobs. News. Profile Search. Company Profile. Merck & Co., Inc. Company Overview Merck and Co., Inc. Merck's product line includes a broad portfolio of highly innovative prescription products in important therapeutic areas. Human health products include medicines to treat high blood pressure, congestive heart failure, elevated cholesterol levels, osteoporosis, benign prostatic hypertrophy, arthritis, pain, migraine, glaucoma, gastrointestinal ulcers, infectious diseases antibiotic, anti-fungal, and antiviral agents , and vaccines to prevent childhood diseases and hepatitis A and B. Merck welcomes partnerships touching virtually all human health therapeutic areas that address unmet needs for patients, as well as technologies that will enhance the productivity of our research laboratories. Therapeutic areas of particular interest include cancer, central nervous system disorders, diabetes, and obesity. Also of interest include the following: anti-infectives, anti-virals, cardiovascular diseases, gastroi...
http://biospace.com/company_profile.aspx?CompanyId=1440
*  Re: No sign of mad cow in 1997 cows (WHY WAS WB USED IN 1997 AND NOT 2004?)VegSource.com
In this case, a USDA veterinarian condemned the cow on April 27 at Lone Star Beef in San Angelo, Texas, because it had signs of a central nervous system disorder. However, the material will be permitted to be used in pig feed because the agency says pigs are not susceptible to mad cow disease. Department of Agriculture has issued an order instructing its inspectors in Texas, where federal mad cow disease testing policies recently were violated, not to talk about the cattle disorder with outside parties, United Press International has learned. The order, sent May 6 by e-mail from the USDA's Dallas district office, was issued in the wake of the April 27 case at Lone Star Beef in San Angelo, in which a cow displaying signs of a brain disorder was not tested for mad cow disease despite a federal policy to screen all such animals. "USDA has acknowledged there was a failure in not testing that cow in Texas for BSE, so we are all working to ensure that does not occur again." Jim Rogers, a spokesman for USDA's Animal...
http://vegsource.com/talk/madcow/messages/94378.html
*  Mefway (18F)
{{drugbox drug name = Mefway 18 F. image = Mefway 18F skeletal.svg IUPAC name = 4- -'N'-{2- ethyl}-'N'- pyridin-2-yl cyclohexane-1-carboxamide synonyms = CAS number = 943962-60-5 PubChem= 11963740 ChemSpiderID = 10137857 ATC prefix = none smiles = COC1=CC=CC=C1N2CCN CC2 CCN C3=CC=CC=N3 C =O C4CCC CC4 C. O=2 molecular weight = 453.583 g/mol StdInChI=1S/C26H35FN4O2/c1-33-24-7-3-2-6-23 24 30-17-14-29 15-18-30 16-19-31 25-8-4-5-13-28-25 26 32 22-11-9-21 20-27 10-12-22/h2-8,13,21-22H,9-12,14-20H2,1H3/i27-1 StdInChIKey = BQGLPDFQLBNUGU-FMLNDMEQSA-N pregnancy category = N/A legal status = Research compound }} 'Mefway' is a serotonin 5-HT 1A. 1 Chemistry Animal PET studies Human PET studies References. Chemistry. Animal PET studies. In one study the uptake and retention of mefway 18 F was found to be similar to that found for 11 C-WAY-100,635. Head-to-head comparison of mefway 18 F and 11 C-WAY-100,635 have been evaluated. The ability to separately measure dissociation constant, K D and receptor density Bmax has been...
https://en.wikipedia.org/wiki/Mefway_(18F)
*  ACAD - ACADIA Pharmaceuticals Inc Company Profile - CNNMoney.com
... . Our Terms of Service and Privacy Policy have changed. By continuing to use this site, you are agreeing to the new Privacy Policy and Terms of Service. Business. Fun with fuel cells: Go off the grid, for good. World. Access. Companies. Car News. Away. Who is... The Feed. Interactives. CNNMoney Investigates. American Opportunity. Innovators. 5 Stunning Stats. Markets. Stocks: 4 things to know before the open. Investing. Economy. Buzz. Trade. ETF Center. Premarkets. Market Movers. Dow 30. After-Hours. World Markets. Investing Guide. The Open. Stockswatch. Tech30. Fear Greed. Tech. Facebook to beam free internet to Africa with satellites. Innovate. Gadget. Connect. Elon. Evolution. Best In Tech. Cyber-Safe. CES. Innovative Cities. 15 Questions With. Love Inc. Sex, Drugs & Silicon Valley. Media. Personal Finance. You're paying record ATM fees. Save. Spend. Ahead. Wheels. Real Estate. Careers Millennials & Money. Your Money. Homes. Calculators. Money Moves. 24 Hours With. Money Essentials. My Watch List. Sma...
http://money.cnn.com/quote/profile/profile.html?symb=ACAD
*  Zogenix Provides Update on Zohydro(TM) ER NDA Nasdaq:ZGNX
Zogenix Provides Update on Zohydro TM ER NDA Nasdaq:ZGNX. 800 307-6627 About Contact Us. Register. Sign In. Tap to Toggle Navigation Menu Newsroom. Pricing. Send Releases. Self Service Publishing. Full Service Publishing. Distribution Options. Reporting Analysis. Search Engine Optimization. Send Releases. Regulatory Filings. PR Solutions. Learning Support. Reader Support. Customer Support. Knowledge Base Archives. Learning Support. Zogenix Provides Update on Zohydro TM ER NDA. October 01, 2013 18:40 ET. Source: Zogenix. SAN DIEGO, Oct. 1, 2013 GLOBE NEWSWIRE -- Zogenix, Inc. Nasdaq: ZGNX, a pharmaceutical company developing and commercializing products for the treatment of central nervous system disorders and pain, announced that it has been informed today by the U.S. Food and Drug Administration FDA that an action letter on the New Drug Application NDA for Zohydro TM ER hydrocodone bitartrate extended-release capsules could follow after a further delay of short duration. The FDA had previously informed the c...
http://globenewswire.com/news-release/2013/10/01/577406/10050859/en/Zogenix-Provides-Update-on-Zohydro-TM-ER-NDA.html
*  History of Pharmacia & Upjohn Inc. – FundingUniverse
History of Pharmacia Upjohn Inc. FundingUniverse. Browse Company Profiles:. 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z. Advertise Here Share This Page Share on Twitter. Share on Facebook. Share on LinkedIn. Share on Google+. Pharmacia Upjohn Inc. History Advertise Here Address:. 95 Corporate Drive Bridgewater, New Jersey 08807 U.S.A. Telephone: 908 306-4400 Toll Free: 888-768-5501 Website: www.pnu.com Public Company Incorporated: 1995 Employees: 30,000 Sales: $6.71 billion 1997 Stock Exchanges: New York Ticker Symbol: PNU SICs: 2834 Pharmaceutical Preparations; 2836 Biological Products, Excluding Diagnostics; 2833 Medicinal Chemicals, Botanical Products; 2835 In Vitro, In Vivo Diagnostics; 8731 Commercial Physical, Biological Research. Company Perspectives: Our goal is to revitalize our company so that we enter the twenty-first century with growing competitive strength. We are developing the people, products, and programs that will lead us to that position. To do all this requires change. Our...
http://fundinguniverse.com/company-histories/pharmacia-upjohn-inc-history/
*  VNDA Nearly Doubles In One Day - Here's Why | InvestorPlaceInvestorPlace
VNDA Nearly Doubles In One Day - Here s Why. InvestorPlaceInvestorPlace. VNDA Stock Nearly Doubles in One Day by Robert Martin. November 13, 2013 9:49 am Shares of Vanda Pharmaceuticals VNDA were trading for just under $7 at the start of the week but they were worth more than $13 by yesterday s close. Why were investors so anxious to snatch up VNDA stock. Well, Vanda Pharmaceuticals is a biopharmaceutical company focused on the development and commercialization of products for the treatment of central nervous system disorders. The Food and Drug Administration FDA is slated to review a VNDA sleep therapy treatment called tasimelteon this Thursday. And yesterday, briefing documents for the upcoming meetings were posted, and Wall Street clearly saw them as promising. Another approved drug would double the number of approved drugs in the VNDA wheelhouse. So far, Vanda Pharmaceuticals only has a schizophrenia treatment. Given the small number of products available, it makes sense that VNDA stock nearly doubled on ...
http://investorplace.com/2013/11/vnda-stock/print
*  Friedrich Christoph Pelizaeus
... right thumb friedrich christoph pelizaeus friedrich christoph pelizaeus april august was a german balneologist and neurologist who was a native of rietberg in he earned his medical doctorate from the university of würzburg and afterwards served as an assistant to karl friedrich ferdinand runge at the resort in nassau an der lahn later he worked as a balneologist at ilmenau kreischa and bad oeynhausen who named it in he received the title of sanitätsrat health advisor pelizaeus died in kassel on august in he provided the first description of a dysmyelinating central nervous system disorder that was to become known as pelizaeus merzbacher disease named in conjunction with neuropathologist ludwig merzbacher references this article is based on a translation of an equivalent article from the polish wikipedia category german physicians category german neurologists category births category deaths category people from rietberg category university of würzburg alumni...
https://en.wikipedia.org/wiki/Friedrich_Christoph_Pelizaeus
*  Insiders Bought These Stocks on Dec-19
... Stock:. Symbol Lookup Register. Login. US Stock Markets ... History ... ... Follow @Twitter. Home. Markets. Stock Market Today. Top Stocks. Pre Market. After Hours. ETFs. Dow Jones Today. Nasdaq. S P. NYSE. AMEX. World Markets. Bonds. Commodities. News. Top Stocks. Pre Market. After Hours. Metals. Metal Prices. Gold Price. Silver Price. Copper Price. Platinum Price. Palladium Price. Econ Calendar. Forex. ETFs. Pre Market. Dow Jones. Gold. Newsletters. Learn. TRADE NOW Select Broker. All News. Market News. Market Commentary. Business. Sports. Politics. Tech. Science. Entertainment. Health. Insiders Bought These Stocks on Dec-19 Friday, December 20, 2013 9:26 AM Insiders purchased shares of the following companies on Thursday, December 19, 2013 Accelrys NASDAQ:ACCL : Moses Robert G purchased 23,066 shares at a price of $8.96. Amtrust Financial Services NASDAQ:AFSI : Karfunkel George purchased 300,000 shares at a price of $28.99. AmTrust Financial Services, Inc. is a multinational specialty property and cas...
http://thestockmarketwatch.com/news/read.aspx/wp/insiders-bought-these-stocks-on-dec-19/49056/

Central nervous system disease: A central nervous system disease can affect either the spinal cord (myelopathy) or brain (encephalopathy), both of which are part of the central nervous system.Neurogastroenterology: Neurogastroenterology encompasses the study of the brain, the gut, and their interactions with relevance to the understanding and management of gastrointestinal motility and functional gastrointestinal disorders. Specifically, neurogastroenterology focuses on the functions, malfunctions, and the malformations of the sympathetic, parasympathetic, and enteric divisions of the digestive tract.Epidemiology of cancer: The epidemiology of cancer is the study of the factors affecting cancer, as a way to infer possible trends and causes. The study of cancer epidemiology uses epidemiological methods to find the cause of cancer and to identify and develop improved treatments.HSD2 neurons: HSD2 neurons are a small group of neurons in the brainstem which are uniquely sensitive to the mineralocorticosteroid hormone aldosterone, through expression of HSD11B2. They are located within the caudal medulla oblongata, in the nucleus of the solitary tract (NTS).Central nervous system viral disease: A central nervous system viral disease is a viral infection that affects the central nervous system.Neuromere: Neuromeres are morphologically or molecularly defined transient segments of the early developing brain. Rhombomeres are such segments that make up the rhombencephalon or hindbrain.Brain healing: Brain healing is the process that occurs after the brain has been damaged. If an individual survives brain damage, the brain has a remarkable ability to adapt.Axon guidance: Axon guidance (also called axon pathfinding) is a subfield of neural development concerning the process by which neurons send out axons to reach the correct targets. Axons often follow very precise paths in the nervous system, and how they manage to find their way so accurately is being researched.ATC code N07: ==N07A Parasympathomimetics==Advanced Pediatric Life Support: Advanced Pediatric Life Support (APLS) is a program created by the American Academy of Pediatrics and the American College of Emergency Physicians to teach health care providers how to take care of sick children.Remyelination: Remyelination is the process of propagating oligodendrocyte precursor cells to form oligodendrocytes to create new myelin sheaths on demyelinated axons in the CNS. This is a process naturally regulated in the body and tends to be very efficient in a healthy CNS.Endoneurium: The endoneurium (also called endoneurial channel, endoneurial sheath, endoneurial tube, or Henle's sheath) is a layer of delicate connective tissue around the myelin sheath of each myelinated nerve fiber. Its component cells are called endoneurial cells.Coles PhillipsParasympatholytic: A parasympatholytic agent is a substance or activity that reduces the activity of the parasympathetic nervous system. (The parasympathetic nervous system is often colloquially described as the "Feed and Breed" or "Rest and Digest" portion of the autonomic nervous system.Astrocyte: Astrocytes (Astro from Greek astron = star and cyte from Greek "kyttaron" = cell), also known collectively as astroglia, are characteristic star-shaped glial cells in the brain and spinal cord. The proportion of astrocytes in the brain is not well defined.Blood–brain barrier: The blood–brain barrier (BBB) is a highly selective permeability barrier that separates the circulating blood from the brain extracellular fluid (BECF) in the central nervous system (CNS). The blood–brain barrier is formed by brain endothelial cells, which are connected by tight junctions with an extremely high electrical resistivity of at least 0.VincristineDemyelinating disease: -, |Protein primary structure: The primary structure of a peptide or protein is the linear sequence of its amino acid structural units, and partly comprises its overall biomolecular structure. By convention, the primary structure of a protein is reported starting from the amino-terminal (N) end to the carboxyl-terminal (C) end.CCL20: Chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or Macrophage Inflammatory Protein-3 (MIP3A) is a small cytokine belonging to the CC chemokine family. It is strongly chemotactic for lymphocytes and weakly attracts neutrophils.Mature messenger RNA: Mature messenger RNA, often abbreviated as mature mRNA is a eukaryotic RNA transcript that has been spliced and processed and is ready for translation in the course of protein synthesis. Unlike the eukaryotic RNA immediately after transcription known as precursor messenger RNA, it consists exclusively of exons, with all introns removed.Temporal analysis of products: Temporal Analysis of Products (TAP), (TAP-2), (TAP-3) is an experimental technique for studyingNeurooncology: Neuro-oncology is the study of brain and spinal cord neoplasms, many of which are (at least eventually) very dangerous and life-threatening (astrocytoma, glioma, glioblastoma multiforme, ependymoma, pontine glioma, and brain stem tumors are among the many examples of these). Among the malignant brain cancers, gliomas of the brainstem and pons, glioblastoma multiforme, and high-grade (highly anaplastic) astrocytoma are among the worst.BESS domain: In molecular biology, the BESS domain is a protein domain which has been named after the three proteins that originally defined the domain: BEAF (Boundary element associated factor 32), Suvar(3)7 and Stonewall ). The BESS domain is 40 amino acid residues long and is predicted to be composed of three alpha helices, as such it might be related to the myb/SANT HTH domain.List of multiple sclerosis organizations: List of Multiple Sclerosis Organizations in different countries around the worldSciatic nerve: The sciatic nerve (; also called ischiadic nerve, ischiatic nerve) is a large nerve in humans and other animals. It begins in the lower back and runs through the buttock and down the lower limb.Drosophila embryogenesis: Drosophila embryogenesis, the process by which Drosophila (fruit fly) embryos form, is a favorite model system for geneticists and developmental biologists studying embryogenesis. The small size, short generation time, and large brood size make it ideal for genetic studies.Gross pathology: Gross pathology refers to macroscopic manifestations of disease in organs, tissues, and body cavities. The term is commonly used by anatomical pathologists to refer to diagnostically useful findings made during the gross examination portion of surgical specimen processing or an autopsy.Neuroregeneration: Neuroregeneration refers to the regrowth or repair of nervous tissues, cells or cell products. Such mechanisms may include generation of new neurons, glia, axons, myelin, or synapses.Neuropeptide S: Neuropeptide S (NPS) is a neuropeptide found in human and mammalian brain, mainly produced by neurons in the amygdala and between Barrington's nucleus and the locus coeruleus, although NPS-responsive neurons extend projections into many other brain areas. NPS binds specifically to a newly de-orphaned G protein-coupled receptor, NPSR.Reticulon: Reticulons (RTNs in vertebrates and reticulon-like proteins or RNTls in other eukaryotes) are a group of evolutionary conservative proteins residing predominantly in endoplasmic reticulum, primarily playing a role in promoting membrane curvature. In addition reticulons may play a role in nuclear pore complex formation, vesicle formation, and other processes yet to be defined.Symmetry element: A symmetry element is a point of reference about which symmetry operations can take place. In particular, symmetry elements can be centers of inversion, axes of rotation and mirror planes.Inferior cerebellar peduncle: The upper part of the posterior district of the medulla oblongata is occupied by the inferior cerebellar peduncle (restiform body), a thick rope-like strand situated between the lower part of the fourth ventricle and the roots of the glossopharyngeal and vagus nerves.P7C3Renshaw cell: Renshaw cells are inhibitory interneurons found in the gray matter of the spinal cord, and are associated in two ways with an alpha motor neuron.Rocio viral encephalitis: Rocio viral encephalitis is an epidemic flaviviral disease of man first observed in São Paulo State, Brazil, in 1975.Carl J.Pug: The Pug is a breed of dog with a wrinkly, short-muzzled face and curled tail. The breed has a fine, glossy coat that comes in a variety of colours, most often fawn or black, and a compact square body with well-developed muscles.Interbeat interval: Interbeat interval is a scientific term used in the study of the mammalian heart.Truncal neural crest: The truncal neural crest or trunk neural crest is a form of neural crest.Leech (disambiguation): Leech is a common name for the annelids comprising the subclass Hirudinea.Silent mutation: Silent mutations are mutations in DNA that do not significantly alter the phenotype of the organism in which they occur. Silent mutations can occur in non-coding regions (outside of genes or within introns), or they may occur within exons.TBR1: T-box, brain, 1 is a transcription factor protein important in vertebrate embryo development. It is encoded by the TBR1 gene.Indy (gene): Indy, short for I'm not dead yet, is a gene of the model organism, the fruit fly Drosophila melanogaster. Mutant versions of this gene have doubled the average life span of fruit flies in at least one set of experiments, but this result has been subject to controversy.Glial fibrillary acidic protein: Glial fibrillary acidic protein (GFAP) is a protein that is encoded by the GFAP gene in humans.Morphant: An organism which has been treated with a morpholino antisense oligo to temporarily knock down expression of a targeted gene is called a morphant.Central tegmental tract: The central tegmental tractKamali A, Kramer LA, Butler IJ, Hasan KM. Diffusion tensor tractography of the somatosensory system in the human brainstem: initial findings using high isotropic spatial resolution at 3.Neurotransmitter: Neurotransmitters are endogenous chemicals that enable neurotransmission. They transmit signals across a chemical synapse, such as in a neuromuscular junction, from one neuron (nerve cell) to another "target" neuron, muscle cell, or gland cell.Renal stem cell: Renal stem cells are self-renewing, multipotent stem cells which are able to give rise to all the cell types of the kidney. It is involved in the homeostasis and repair of the kidney, and holds therapeutic potential for treatment of kidney failure.Myelin basic protein: Myelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the nervous system. The myelin sheath is a multi-layered membrane, unique to the nervous system, that functions as an insulator to greatly increase the velocity of axonal impulse conduction.Pituitary-specific positive transcription factor 1: POU domain, class 1, transcription factor 1 (Pit1, growth hormone factor 1), also known as POU1F1, is a transcription factor for growth hormone.Silent synapse: In neuroscience, a silent synapse is an excitatory glutamatergic synapse whose postsynaptic membrane contains NMDA-type glutamate receptors but no AMPA-type glutamate receptors. These synapses are named "silent" because normal AMPA receptor-mediated signaling is not present, rendering the synapse inactive under typical conditions.

(1/3565) Mercury and Mink. II. Experimental methyl mercury intoxication.

Adult female mink were fed rations containing 1.1, 1.8, 4.8, 8.3 and 15.0 ppm mercury as methyl mercury chloride over a 93 day period. Histopathological evidence of injury was present in all groups. Mink fed rations containing 1.8 to 15.0 ppm mercury developed clinical intoxication within the experimental period. The rapidity of onset of clinical intoxication was directly related to the mercury content of the ration. Mercury concentration in tissue of mink which died were similar, despite differences in mercury content of the diets and time of death. The average mercury concentration in the brain of mink which died was 11.9 ppm. The lesions of methyl mercury poisoning are described and criteria for diagnosis are discussed.  (+info)

(2/3565) Deletion analysis of the Drosophila Inscuteable protein reveals domains for cortical localization and asymmetric localization.

The Drosophila Inscuteable protein acts as a key regulator of asymmetric cell division during the development of the nervous system [1] [2]. In neuroblasts, Inscuteable localizes into an apical cortical crescent during late interphase and most of mitosis. During mitosis, Inscuteable is required for the correct apical-basal orientation of the mitotic spindle and for the asymmetric segregation of the proteins Numb [3] [4] [5], Prospero [5] [6] [7] and Miranda [8] [9] into the basal daughter cell. When Inscuteable is ectopically expressed in epidermal cells, which normally orient their mitotic spindle parallel to the embryo surface, these cells reorient their mitotic spindle and divide perpendicularly to the surface [1]. Like the Inscuteable protein, the inscuteable RNA is asymmetrically localized [10]. We show here that inscuteable RNA localization is not required for Inscuteable protein localization. We found that a central 364 amino acid domain - the Inscuteable asymmetry domain - was necessary and sufficient for Inscuteable localization and function. Within this domain, a separate 100 amino acid region was required for asymmetric localization along the cortex, whereas a 158 amino acid region directed localization to the cell cortex. The same 158 amino acid fragment could localize asymmetrically when coexpressed with the full-length protein, however, and could bind to Inscuteable in vitro, suggesting that this domain may be involved in the self-association of Inscuteable in vivo.  (+info)

(3/3565) From head to toes: the multiple facets of Sox proteins.

Sox proteins belong to the HMG box superfamily of DNA-binding proteins and are found throughout the animal kingdom. They are involved in the regulation of such diverse developmental processes as germ layer formation, organ development and cell type specifi-cation. Hence, deletion or mutation of Sox proteins often results in developmental defects and congenital disease in humans. Sox proteins perform their function in a complex interplay with other transcription factors in a manner highly dependent on cell type and promoter context. They exhibit a remarkable crosstalk and functional redundancy among each other.  (+info)

(4/3565) The psychometric properties of clinical rating scales used in multiple sclerosis.

OullII;l y Many clinical rating scales have been proposed to assess the impact of multiple sclerosis on patients, but only few have been evaluated formally for reliability, validity and responsiveness. We assessed the psychometric properties of five commonly used scales in multiple sclerosis, the Expanded Disability Status Scale (EDSS), the Scripps Neurological Rating Scale (SNRS), the Functional Independence Measure (FIM), the Ambulation Index (AI) and the Cambridge Multiple Sclerosis Basic Score (CAMBS). The score frequency distributions of all five scales were either bimodal (EDSS and AI) or severely skewed (SNRS, FIM and CAMBS). The reliability of each scale depended on the definition of 'agreement'. Inter-and intra-rater reliabilities were high when 'agreement' was considered to exist despite a difference of up to 1.0 EDSS point (two 0.5 steps), 13 SNRS points, 9 FIM points, 1 AI point and 1 point on the various CAMBS domains. The FIM, AI, and the relapse and progression domains of the CAMBS were sensitive to clinical change, but the EDSS and the SNRS were unresponsive. The validity of these scales as impairment (SNRS and EDSS) and disability (EDSS, FIM, AI and the disability domain of the CAMBS) measures was established. All scales correlated closely with other measures of handicap and quality of life. None of these scales satisfied the psychometric requirements of outcome measures completely, but each had some desirable properties. The SNRS and the EDSS were reliable and valid measures of impairment and disability, but they were unresponsive. The FIM was a reliable, valid and responsive measure of disability, but it is cumbersome to administer and has a limited content validity. The AI was a reliable and valid ambulation-related disability scale, but it was weakly responsive. The CAMBS was a reliable (all four domains) and responsive (relapse and progression domains) outcome measure, but had a limited validity (handicap domain). These psychometric properties should be considered when designing further clinical trials in multiple sclerosis.  (+info)

(5/3565) beta-thymosin is required for axonal tract formation in developing zebrafish brain.

beta-Thymosins are polypeptides that bind monomeric actin and thereby function as actin buffers in many cells. We show that during zebrafish development, &bgr;-thymosin expression is tightly correlated with neuronal growth and differentiation. It is transiently expressed in a subset of axon-extending neurons, essentially primary neurons that extend long axons, glia and muscle. Non-neuronal expression in the brain is restricted to a subset of glia surrounding newly forming axonal tracts. Skeletal muscle cells in somites, jaw and fin express beta-thymosin during differentiation, coinciding with the time of innervation. Injection of beta-thymosin antisense RNA into zebrafish embryos results in brain defects and impairment of the development of beta-thymosin-associated axon tracts. Furthermore, irregularities in somite formation can be seen in a subset of embryos. Compared to wild-type, antisense-injected embryos show slightly weaker and more diffuse engrailed staining at the midbrain-hindbrain boundary and a strong reduction of Isl-1 labeling in Rohon Beard and trigeminal neurons. The decreased expression is not based on a loss of neurons indicating that beta-thymosin may be involved in the maintenance of the expression of molecules necessary for neuronal differentiation. Taken together, our results strongly indicate that beta-thymosin is an important regulator of development.  (+info)

(6/3565) The Caenorhabditis elegans lim-6 LIM homeobox gene regulates neurite outgrowth and function of particular GABAergic neurons.

We describe here the functional analysis of the C. elegans LIM homeobox gene lim-6, the ortholog of the mammalian Lmx-1a and b genes that regulate limb, CNS, kidney and eye development. lim-6 is expressed in a small number of sensory-, inter- and motorneurons, in epithelial cells of the uterus and in the excretory system. Loss of lim-6 function affects late events in the differentiation of two classes of GABAergic motorneurons which control rhythmic enteric muscle contraction. lim-6 is required to specify the correct axon morphology of these neurons and also regulates expression of glutamic acid decarboxylase, the rate limiting enzyme of GABA synthesis in these neurons. Moreover, lim-6 gene activity and GABA signaling regulate neuroendocrine outputs of the nervous system. In the chemosensory system lim-6 regulates the asymmetric expression of a probable chemosensory receptor. lim-6 is also required in epithelial cells for uterine morphogenesis. We compare the function of lim-6 to those of other LIM homeobox genes in C. elegans and suggest that LIM homeobox genes share the common theme of controlling terminal neural differentiation steps that when disrupted lead to specific neuroanatomical and neural function defects.  (+info)

(7/3565) Engrailed negatively regulates the expression of cell adhesion molecules connectin and neuroglian in embryonic Drosophila nervous system.

Engrailed is expressed in subsets of interneurons that do not express Connectin or appreciable Neuroglian, whereas other neurons that are Engrailed negative strongly express these adhesion molecules. Connectin and Neuroglian expression are virtually eliminated in interneurons when engrailed expression is driven ubiquitously in neurons, and greatly increased when engrailed genes are lacking in mutant embryos. The data suggest that Engrailed is normally a negative regulator of Connectin and neuroglian. These are the first two "effector" genes identified in the nervous system of Drosophila as regulatory targets for Engrailed. We argue that differential Engrailed expression is crucial in determining the pattern of expression of cell adhesion molecules and thus constitutes an important determinant of neuronal shape and perhaps connectivity.  (+info)

(8/3565) Profilin and the Abl tyrosine kinase are required for motor axon outgrowth in the Drosophila embryo.

The ability of neuronal growth cones to be guided by extracellular cues requires intimate communication between signal transduction systems and the dynamic actin-based cytoskeleton at the leading edge. Profilin, a small, actin-binding protein, has been proposed to be a regulator of the cell motility machinery at leading edge membranes. However, its requirement in the developing nervous system has been unknown. Profilin associates with members of the Enabled family of proteins, suggesting that Profilin might link Abl function to the cytoskeleton. Here, genetic analysis in Drosophila is used to demonstrate that mutations in Profilin (chickadee) and Abl (abl) display an identical growth cone arrest phenotype for axons of intersegmental nerve b (ISNb). Moreover, the phenotype of a double mutant suggests that these components function together to control axonal outgrowth.  (+info)


Nervous system?


Which vitamin is best for nervous system?
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Your body needs a balance of all vitamins, plus healthy food, water, rest and exercise.  Calcium, magnesium, iron, omega oils, vitamin b- all are necessary.


nervous system ?


how does your nervous system react when you have an injury?

and what happends if your nervous system does not work properly?
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It depends on the injury and how extensive, but most common reaction of nervous system when injury happens is seizures. Seizures is brains way of expressing a problem.Seizures are even more likely with head injury, but seizures can be triggered by a number of things (high fever, stress, medication side effects, etc.). The Nervous System may react in many other ways to injury, I just have knowledge and experience concerning seizures!


Nervous System?


What happens when the nervous system shuts down?
yes, i have heard of the term vegetable
and dot answer this question unless u really know
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you die.


how does the nervous system work with the respiratory system? How do they work together?


Does the respiratory system and the nervous system actually work together?
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The nervous system effects every single part of your body. The nervous system consists of every nerve tissue in the body. You have nerve tissue in your fingers to tell you when something is hot or cold, in your stomach to let the brain know to send the impulses that digest food, and in your lungs to tell you when to breathe and how much air to breathe in. There are 3 respiratory centers in the brain that control the respiratory rate.

There are stretch receptors in the lungs that tell the brain that the alveoli are completely expanded and that it is time to stop breathing. Your breathing also controls the acidity of the blood. If the blood gets too acidic, the brain tells you to breathe faster to release carbon dioxide. There are also receptors that tell you when to cough, sneeze, sigh (breathe in deeper), etc.

In addition to all of that, you have smooth muscle (involntary muscle) lining the respiratory tract. The nervous system tells the smooth muscle when to contract and when to dialate in response to various stimulation. There are many, many, many stimuli that cause responses - far too many to go over here.


What do the integumetary and the nervous system have in common?


I am 12, and doing a project on human body matchmaking. It's srtof like, a dateing thing, ex.- the immune system likes to fight because it likes to fight off disease. So it would be perfect going with the integumentary, which is protective because it likes to protect the skin from anything that could hurt. I really cannot find anything that would make the integumentay and the nervous system go together. Or any qualitys that it could have. HELP!! I REALLY WANT A GOOD GRADEEE!
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Well, the integumentary system is the essentially the skin, which is the largest organ in the body, since it covers your entire body. The nervous system also covers the entire body, so it too is very large. They have that in common.


What body system does brain tumor affect besides nervous system?


I have this project and I have to write an essay about a disorder. So I choose brain tumor. I know brain tumor affects the nervous system. I need to write what other system does it affect due to brain tumor and the damage of the nervous system? PLEASE HELP ME!!!! THANK YOU!!
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It depends on where the tumor is inside the brain, and whether it's benign or malignant. If it's malignant, it will probably cause the whole body to die unless you have it removed, and even then, it's likely to return. There are many different kinds of brain tumors, and I just mentioned two large categories of brain tumors. I would recommend looking at an anatomy drawing of the brain that's labeled with the functions that each part is primarily responsible for. For example, the pre-frontal cortex is responsible for planning, decision-making, maturity, advanced self-control and emotional self-control, learning from your experience, and inhibition of risk-taking. If you damage this section of the brain, you will have problems with one or more of those things.


Is there a relationship between the sympathetic nervous system and extreme sickness?


I'm not exactly sure what the sympathetic/parasympathetic nervous system is, but is there any relationship between them and extreme sickness? For example, you eat food that went bad and you feel so sick that you think you're going to die...will either of those nervous systems do anything in response?
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The short answer is, yes, the sympathetic nervous system responds to rotten food.

The SNS is geared to mobilize the body's resources under stress, to induce the flight or fight response, and it's contstantly active at the basal level maintaining homeostasis. The sympathetic nerves originate inside the vertebral column toward the middle of the spinal column.

Rotten food sets it off, since the SNS aids in the control of most of our internal organs, including release of neurotransmitters (brain chemicals), dilation of pupils, gut motility and urinary output, digestion, increases renin in kidneys, increases rate and force of heart contraction, releases adrenaline into the blood, and promotes ejaculation in the penis.


What is the influence of music on our nervous system?


I read on a book that music cause a negative effect on nervous system, it will reduce the ability of concentration and memory.
Blood pressure and so on... I want just your idea to confirm it or not?
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Depends upon the individual and what kind of music.  Classical music seems to help.  Some classic rock is also beneficial.  Very loud heavy metal, well studies with mice have shown that Rave conditions conbined with amphetamine type drugs can kill.