No data available that match "Models, Genetic"



*  Genetic Algorithm Based Optimization Model for Reliable Data Storage in Cloud...
... pp Genetc Algorthm Based Optmzaton Model for Relable Data Storage n Cloud Envronment Feng ... Optimization Model of Reliable Data Storage in Cloud Environment Using Genetic Algorithm ... Download "Genetic Algorithm Based Optimization Model for Reliable Data Storage in Cloud ... An MILP model for planning of batch plants operating in a campaign-mode An MILP model for ......
http://docplayer.net/2001017-Genetic-algorithm-based-optimization-model-for-reliable-data-storage-in-cloud-environment.html
*  CELLS alive! Glossary
Explore more in the Eukaryotic Cell Model.. Granulocyte Any of a type of white blood ... It contains most of the genetic material of the organism, while additional genes are ... Explore the Bacterial Cell Model.. Giardiasis A disease also called "beaver fever" caused ... Deoxyribonucleic Acid, DNA Self-replicating macromolecule containing the genetic code of ......
http://cellsalive.com/glossary_d-g.htm
*  Modeling Viral Infections and Immunity | GEN
Prenatal Genetic Testing Looks to Single-Cell Methods as the Next Frontier ... Modeling Viral Infections and Immunity May 1 - May 4, 2017 / Estes Park, CA, UNITED ......
http://genengnews.com/events/modeling-viral-infections-and-immunity/5594
*  S102 SOX2 initiates carcinogenesis in a novel organotypic model of bronchial...
Loss of TP53 and PTEN are co-operating genetic events that potentiate the dysplastic ... This model can be used to test the impact of therapeutic agents aimed at chemoprevention ... To develop a 3D in vitro model of bronchial dysplasia that recapitulates key molecular ... S102 SOX2 initiates carcinogenesis in a novel organotypic model of bronchial dysplasia ......
http://thorax.bmj.com/content/70/Suppl_3/A58.1
*  The Lethal Phenotype of Cancer: The Molecular Basis of Death Due to Malignancy ...
... a model of metastatic potential by multiple genetic programs. Cancer Detect Prev 2005; 29 ... On their inherited genetic background, cells are assaulted by a variety of gene-damaging ... Integrative molecular concept modeling of prostate cancer progression. Nat Genet 2007; 39 ... The molecular events that define the lethal phenotype of various cancers-the genetic and ......
http://onlinelibrary.wiley.com/doi/10.3322/canjclin.57.4.225/full?globalMessage=0
*  20 Stars You Forgot Appeared In Veronica Mars | Screen Rant
The Genetic Opera, The O.C., and Supernatural. She also has a career in music and as a ... that America's Next Top Model contestant Kim Stolz got to cameo in after winning a ... specifically the strange partnership with America's Next Top Model that resulted in ......
http://screenrant.com/20-stars-you-forgot-appeared-on-veronica-mars/
*  British Library EThOS: Reductionist animal models to probe protein O...
Various genetic approaches in several animal models have revealed that protein O- ... Reductionist animal models to probe protein O-GlcNAcylation Author: Selvan, Nithya ISNI: ... In a search for a reductionist model with a small proteome to dissect the general global ... Embryonic development in a genetically tractable organism is thus a model in which the ......
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.676031
*  Genetic variant associations of human SP-A and SP-D with acute and chronic lung...
... pulmonary surfactant protein A genetic variants as a model. Comp Biochem Physiol A Mol ... Disease susceptibility is influenced by a number of overlapping genetic and non genetic ... and other genetic and non-genetic factors are a necessary extension of this work, and ... Genetic variant associations of human SP-A and SP-D with acute and chronic lung injury. ......
http://pubmedcentralcanada.ca/pmcc/articles/PMC3635489/?lang=en-ca
*  British Library EThOS: Genetic control of corneal epithelial cell migration by...
... there was no genetic model 'of defective 'wound-induced currents. paxrt'l- eyes were ... Genetic control of corneal epithelial cell migration by Pax6 Author: Kucerova, Romana ... Clarifying the mechanisms guiding cell migration in an experimentally accessible model of ... cells were used as model because the cells previously showed compromised or reverse ......
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485667
*  Medical Definition of Laboratory, Jackson
Little believed that mouse models held the key to understanding the genetic basis of ... Today the scientific community recognizes the mouse as one of the most important models ... The premiere place for mouse genetics and the largest mammalian genetic research facility ... as a Basic Cancer Center dedicated to advancing the understanding of the genetic factors ......
http://emedicinehealth.com/script/main/art.asp?articlekey=16005

No data available that match "Models, Genetic"



(1/26926) A genetic model of substrate deprivation therapy for a glycosphingolipid storage disorder.

Inherited defects in the degradation of glycosphingolipids (GSLs) cause a group of severe diseases known as GSL storage disorders. There are currently no effective treatments for the majority of these disorders. We have explored a new treatment paradigm, substrate deprivation therapy, by constructing a genetic model in mice. Sandhoff's disease mice, which abnormally accumulate GSLs, were bred with mice that were blocked in their synthesis of GSLs. The mice with simultaneous defects in GSL synthesis and degradation no longer accumulated GSLs, had improved neurologic function, and had a much longer life span. However, these mice eventually developed a late-onset neurologic disease because of accumulation of another class of substrate, oligosaccharides. The results support the validity of the substrate deprivation therapy and also highlight some limitations.  (+info)

(2/26926) A computational screen for methylation guide snoRNAs in yeast.

Small nucleolar RNAs (snoRNAs) are required for ribose 2'-O-methylation of eukaryotic ribosomal RNA. Many of the genes for this snoRNA family have remained unidentified in Saccharomyces cerevisiae, despite the availability of a complete genome sequence. Probabilistic modeling methods akin to those used in speech recognition and computational linguistics were used to computationally screen the yeast genome and identify 22 methylation guide snoRNAs, snR50 to snR71. Gene disruptions and other experimental characterization confirmed their methylation guide function. In total, 51 of the 55 ribose methylated sites in yeast ribosomal RNA were assigned to 41 different guide snoRNAs.  (+info)

(3/26926) Familial antiphospholipid antibody syndrome: criteria for disease and evidence for autosomal dominant inheritance.

OBJECTIVE: To develop diagnostic criteria for a familial form of antiphospholipid antibody syndrome (APS), identify families with >1 affected member, examine possible modes of inheritance, and determine linkage to potential candidate genes. METHODS: Family members of probands with primary APS were analyzed for clinical and laboratory abnormalities associated with APS. Families with > or =2 affected members were analyzed by segregation analysis and typed for candidate genetic markers. RESULTS: Seven families were identified. Thirty of 101 family members met diagnostic criteria for APS. Segregation studies rejected both environmental and autosomal recessive models, and the data were best fit by either a dominant or codominant model. Linkage analysis showed independent segregation of APS and several candidate genes. CONCLUSION: Clinical and laboratory criteria are essential to identify the spectrum of disease associated with APS. We believe a set of criteria was developed that can precisely define affected family members with APS. Modeling studies utilizing these criteria strongly support a genetic basis for disease in families with APS and suggest that a susceptibility gene is inherited in an autosomal dominant pattern. However, in these families, APS was not linked with HLA, Fas, or other candidate genes, including beta2-glycoprotein 1, HLA, T cell receptor beta chain, Ig heavy chain, antithrombin III, Fas ligand, factor V, complement factor H, IgK, and Fas.  (+info)

(4/26926) Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice.

To study the effect of continued telomere shortening on chromosome stability, we have analyzed the telomere length of two individual chromosomes (chromosomes 2 and 11) in fibroblasts derived from wild-type mice and from mice lacking the mouse telomerase RNA (mTER) gene using quantitative fluorescence in situ hybridization. Telomere length at both chromosomes decreased with increasing generations of mTER-/- mice. At the 6th mouse generation, this telomere shortening resulted in significantly shorter chromosome 2 telomeres than the average telomere length of all chromosomes. Interestingly, the most frequent fusions found in mTER-/- cells were homologous fusions involving chromosome 2. Immortal cultures derived from the primary mTER-/- cells showed a dramatic accumulation of fusions and translocations, revealing that continued growth in the absence of telomerase is a potent inducer of chromosomal instability. Chromosomes 2 and 11 were frequently involved in these abnormalities suggesting that, in the absence of telomerase, chromosomal instability is determined in part by chromosome-specific telomere length. At various points during the growth of the immortal mTER-/- cells, telomere length was stabilized in a chromosome-specific man-ner. This telomere-maintenance in the absence of telomerase could provide the basis for the ability of mTER-/- cells to grow indefinitely and form tumors.  (+info)

(5/26926) Plasmid replication initiator protein RepD increases the processivity of PcrA DNA helicase.

The replication initiator protein RepD encoded by the Staphylococcus chloramphenicol resistance plasmid pC221 stimulates the helicase activity of the Bacillus stearothermophilus PcrA DNA helicase in vitro. This stimulatory effect seems to be specific for PcrA and differs from the stimulatory effect of the Escherichia coli ribosomal protein L3. Whereas L3 stimulates the PcrA helicase activity by promoting co-operative PcrA binding onto its DNA substrate, RepD stimulates the PcrA helicase activity by increasing the processivity of the enzyme and enables PcrA to displace DNA from a nicked substrate. The implication of these results is that PcrA is the helicase recruited into the replisome by RepD during rolling circle replication of plasmids of the pT181 family.  (+info)

(6/26926) Transplacement mutagenesis: a novel in situ mutagenesis system using phage-plasmid recombination.

Site-specific mutagenesis provides the ability to alter DNA with precision so that the function of any given gene can be more fully understood. Several methods of in vitro mutagenesis are time-consuming and imprecise, requiring the subcloning and sequencing of products. Here we describe a rapid, high fidelity method of in situ mutagenesis in bacteriophage lambda using transplacement. Using this method, mutations are transferred from oligonucleotides to target phages using a plasmid interface. A small (50 bp) homology region bearing a centred point mutation is generated from oligonucleotides and subcloned into a transplacement plasmid bearing positive and negative phage selectable markers. Following a positive/negative selection cycle of integrative recombination and excision, the point mutation is transferred precisely from plasmid to phage in a subset ( approximately 25-50%) of recombinants. As the fidelity of both oligonucleotide synthesis and phage-plasmid recombination is great, this approach is extremely reliable. Using transplacement, point mutations can be accurately deposited within large phage clones and we demonstrate the utility of this technique in the construction of gene targeting vectors in bacteriophages.  (+info)

(7/26926) Rapid modification of bacterial artificial chromosomes by ET-recombination.

We present a method to modify bacterial artificial chromosomes (BACs) resident in their host strain. The method is based on homologous recombination by ET-cloning. We have successfully modified BACs at two distinct loci by recombination with a PCR product containing homology arms of 50 nt. The procedure we describe here is rapid, was found to work with high efficiency and should be applicable to any BAC modification desired.  (+info)

(8/26926) Amplification of cDNA ends based on template-switching effect and step-out PCR.

A new method for amplifying cDNA ends is described which requires only first-strand cDNA synthesis and a single PCR to generate a correct product with very low or no background. The method can be successfully applied to total RNA as well as poly A+ RNA. The same first-strand cDNA can be used to amplify flanking sequences of any cDNA species present in the sample.  (+info)


What kind of modeling agencies accept glamour models?


What I mean is, when I look at playboy models and video models, they don't look like fashion models.  What kind of agency accepts glamour models that are shorter than the high fashion model?
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From what ive seen there isnt a particular big glam agency, you more so try to make direct contact with a publication and send them pics.  Glam models arent your usual fashion models like you said they are shorter then most models.  Start off by finding a photographer you are comfortable with and get a portofolio together.  Once you have a variety of poses you are willing to take use that to shop yourself around with any magazines in the area.


What is modeling,who is a model and how do models make money?What do modeling agents do?


What is modeling,who is a model and how do models make money?What do modeling agents do?
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A model is a person who appears in magazines, ad campaigns, catalogues, fashion shows, billboards, etc often selling a product or representing a designer. The agent is the one who finds the work for models. Models get paid by the clients who book them and the agent takes a 10-15% commission

So Vogue magazine needs models to wear the clothes on the page, They call various agencies and have a bunch of models come to the office and decide which one they want for the shoot. Then they pay the agency, and the agency takes their commission and pays the model


What is the link between atheletes/models/etc and binge-eating disorders?


I read somewhere that atheletes and models- or any other professionals whose bodies are on "public display on a frequent basis"- notably struggle with binge-eating disorders where they rapidly and excessively consume foods at certain periods of time, usually due to depression, anxiety, boredom, etc. 

It seems sort of odd to me that this is the case, considering atheletes and models are usually very slender. 

What do you guys think are some of the links?
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You are asking about two very different groups of people. 

When it comes to elite level athletes, yes, there are certain sports where eating disorders are a big problem. It has less to do with "bodies on display" than with "if I lose 5 kg I'll shave 5 seconds off my time" or similar. You can, for example, look into ski jumping, where a minimum BMI has been set due to  jumpers losing as much weight as they can - to unhealthy low lovels - to be able to fly further on their jumps. 

Models are on public display, but they also have to maintain a certain body type as their role is a living hanger for the clothes. Unlike with (most) athletes, models can and do use illicit drugs to keep their weight down.

Now there will be binging and purging in both groups, but I do not know to what extent it exists.


What are the names of the abercrombie and fitch models in Hawaii?


Recently while shopping, I saw some male models at the front of both the womens and mens store at the Ala Moana Shopping centre in Hawaii. Are they workers or models?
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models


What do modeling agencies look at in models?


When a model applies to a modeling agency, do they care about the colour of the eyes and hair? I've noticed that the majority of models are either blonde with blue eyes or brown hair with blue or green eyes. Also, for runway models, is the body more important than the looks?
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No, however say an agency has mainly blonde/blue eyed models, then they will likely be looking for brown/black eyed/hair models to expand their selection. In general, the modeling industry doesn't really favor a specific eye or hair color. (Eastern Europeans are very popular, they have light eyes and hair but to balance that Brazilians are also very popular who mainly have dark eyes and hair)!


What do modeling agencies look for in aspiring fashion models?


I'm talking about models who end up in shows such as fashion week. I would particularly like to know how much the models are supposed to weigh. Do modeling agencies really care about how much they weigh, or is it just as long as they're skinny?
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Agencies look for, firstly, a girl who has the right measurements; ideally 32-24-24 and 5'10". Weight doesn't matter so long as they fit these parameters. If you are looking for specific weight, I would say most runway models are weighing between 55-65kg. Model scouts also look for interesting faces— models such as Kelly Mittendorf and Marie Piovesan are successful newcomers who have features outside of the norm. 

Celebrities and socialites sometimes are able to break into modelling because of their "connections" and wealth, which is why they're able to get away with being heavier/curvier or shorter. For an average model, it's all about measurements.


What is the difference between centerfolds and fashion models?


Are centerfolds considered to be models? I say no because they model for lust, whereas fashion models are used to sell or market clothes through campaigns, runways, and magazines. Can anyone provide a clear explanation between these professions?
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They are both considered models.

One models for the fashion industry to sell clothes. The other models for the adult entertainment industry to sell its products.They both model to sell some sort of product. Although the fashion model usually has clothes on, and the other models nude usually, but sometimes the roles are reversed and the fashion model can sometimes model nude, but they are still selling some sort of fashion item. 

I think the main different is the fashion model, models to sell a fashion item. While the centerfold model, models to sell nude images of themselves which is the actual product, and not usually an item outside of that (at least most of the time).


What kind of a diet do male models and actors have?


I'm talking about male movie stars, male models, and male adult film stars.  I know they spend a lot of time in the gym, but what about their diet?

Can they never eat any fatty foods or just limit the bad food they eat?

Or do they only work out a lot when they have an upcoming movie or photoshoot and just kind of let themselves go a little when they are not working?
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Sex, Alchol and Parties. I have a male model friend - he's all about that. I keep annoying him with "stop, you are harming yourself" comments! ==>>Don't do it!