Complex mental function having four distinct phases: (1) memorizing or learning, (2) retention, (3) recall, and (4) recognition. Clinically, it is usually subdivided into immediate, recent, and remote memory.
Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions.
Remembrance of information for a few seconds to hours.
The altered state of immunologic responsiveness resulting from initial contact with antigen, which enables the individual to produce antibodies more rapidly and in greater quantity in response to secondary antigenic stimulus.
Remembrance of information from 3 or more years previously.
Type of declarative memory, consisting of personal memory in contrast to general knowledge.
The process whereby a representation of past experience is elicited.
Learning the correct route through a maze to obtain reinforcement. It is used for human or animal populations. (Thesaurus of Psychological Index Terms, 6th ed)
Tests designed to assess neurological function associated with certain behaviors. They are used in diagnosing brain dysfunction or damage and central nervous system disorders or injury.
The persistence to perform a learned behavior (facts or experiences) after an interval has elapsed in which there has been no performance or practice of the behavior.
The knowledge or perception that someone or something present has been previously encountered.
A curved elevation of GRAY MATTER extending the entire length of the floor of the TEMPORAL HORN of the LATERAL VENTRICLE (see also TEMPORAL LOBE). The hippocampus proper, subiculum, and DENTATE GYRUS constitute the hippocampal formation. Sometimes authors include the ENTORHINAL CORTEX in the hippocampal formation.
Relatively permanent change in behavior that is the result of past experience or practice. The concept includes the acquisition of knowledge.
The principle that items experienced together enter into a connection, so that one tends to reinstate the other.
Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)
Learning to respond verbally to a verbal stimulus cue.
The affective response to an actual current external danger which subsides with the elimination of the threatening condition.
Reactions of an individual or groups of individuals with relation to the immediate surrounding area including the animate or inanimate objects within that area.
Intellectual or mental process whereby an organism obtains knowledge.
A response to a cue that is instrumental in avoiding a noxious experience.
A general term referring to the learning of some particular response.
The time from the onset of a stimulus until a response is observed.
A critical subpopulation of regulatory T-lymphocytes involved in MHC Class I-restricted interactions. They include both cytotoxic T-lymphocytes (T-LYMPHOCYTES, CYTOTOXIC) and CD8+ suppressor T-lymphocytes.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
Learning that takes place when a conditioned stimulus is paired with an unconditioned stimulus.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
Disturbances in mental processes related to learning, thinking, reasoning, and judgment.
The coordination of a sensory or ideational (cognitive) process and a motor activity.
The observable response an animal makes to any situation.
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Focusing on certain aspects of current experience to the exclusion of others. It is the act of heeding or taking notice or concentrating.
The rostral part of the frontal lobe, bounded by the inferior precentral fissure in humans, which receives projection fibers from the MEDIODORSAL NUCLEUS OF THE THALAMUS. The prefrontal cortex receives afferent fibers from numerous structures of the DIENCEPHALON; MESENCEPHALON; and LIMBIC SYSTEM as well as cortical afferents of visual, auditory, and somatic origin.
Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.
Signals for an action; that specific portion of a perceptual field or pattern of stimuli to which a subject has learned to respond.
Almond-shaped group of basal nuclei anterior to the INFERIOR HORN OF THE LATERAL VENTRICLE of the TEMPORAL LOBE. The amygdala is part of the limbic system.
Lower lateral part of the cerebral hemisphere responsible for auditory, olfactory, and semantic processing. It is located inferior to the lateral fissure and anterior to the OCCIPITAL LOBE.
Inbred C57BL mice are a strain of laboratory mice that have been produced by many generations of brother-sister matings, resulting in a high degree of genetic uniformity and homozygosity, making them widely used for biomedical research, including studies on genetics, immunology, cancer, and neuroscience.
The active mental process of keeping out and ejecting, banishing from consciousness, ideas or impulses that are unacceptable to it.
Investigative technique commonly used during ELECTROENCEPHALOGRAPHY in which a series of bright light flashes or visual patterns are used to elicit brain activity.
Elements of limited time intervals, contributing to particular results or situations.
Loss of the ability to recall information that had been previously encoded in memory prior to a specified or approximate point in time. This process may be organic or psychogenic in origin. Organic forms may be associated with CRANIOCEREBRAL TRAUMA; CEREBROVASCULAR ACCIDENTS; SEIZURES; DEMENTIA; and a wide variety of other conditions that impair cerebral function. (From Adams et al., Principles of Neurology, 6th ed, pp426-9)
The capacity of the NERVOUS SYSTEM to change its reactivity as the result of successive activations.
A critical subpopulation of T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the T4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes.
A persistent increase in synaptic efficacy, usually induced by appropriate activation of the same synapses. The phenomenological properties of long-term potentiation suggest that it may be a cellular mechanism of learning and memory.
The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Mental process to visually perceive a critical number of facts (the pattern), such as characters, shapes, displays, or designs.
Learning in which the subject must respond with one word or syllable when presented with another word or syllable.
The tendency to explore or investigate a novel environment. It is considered a motivation not clearly distinguishable from curiosity.
Prominent lobed neuropils found in ANNELIDA and all ARTHROPODS except crustaceans. They are thought to be involved in olfactory learning and memory.
The life of a person written by himself or herself. (Harrod's Librarians' Glossary, 7th ed)
The selecting and organizing of visual stimuli based on the individual's past experience.
A classification of T-lymphocytes, especially into helper/inducer, suppressor/effector, and cytotoxic subsets, based on structurally or functionally different populations of cells.
A set of cognitive functions that controls complex, goal-directed thought and behavior. Executive function involves multiple domains, such as CONCEPT FORMATION, goal management, cognitive flexibility, INHIBITION control, and WORKING MEMORY. Impaired executive function is seen in a range of disorders, e.g., SCHIZOPHRENIA; and ADHD.
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.
Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.
An outbred strain of rats developed in 1915 by crossing several Wistar Institute white females with a wild gray male. Inbred strains have been derived from this original outbred strain, including Long-Evans cinnamon rats (RATS, INBRED LEC) and Otsuka-Long-Evans-Tokushima Fatty rats (RATS, INBRED OLETF), which are models for Wilson's disease and non-insulin dependent diabetes mellitus, respectively.
Conditions characterized by a significant discrepancy between an individual's perceived level of intellect and their ability to acquire new language and other cognitive skills. These disorders may result from organic or psychological conditions. Relatively common subtypes include DYSLEXIA, DYSCALCULIA, and DYSGRAPHIA.
Those affective states which can be experienced and have arousing and motivational properties.
The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.
Loss of the ability to form new memories beyond a certain point in time. This condition may be organic or psychogenic in origin. Organically induced anterograde amnesia may follow CRANIOCEREBRAL TRAUMA; SEIZURES; ANOXIA; and other conditions which adversely affect neural structures associated with memory formation (e.g., the HIPPOCAMPUS; FORNIX (BRAIN); MAMMILLARY BODIES; and ANTERIOR THALAMIC NUCLEI). (From Memory 1997 Jan-Mar;5(1-2):49-71)
An alkaloid from SOLANACEAE, especially DATURA and SCOPOLIA. Scopolamine and its quaternary derivatives act as antimuscarinics like ATROPINE, but may have more central nervous system effects. Among the many uses are as an anesthetic premedication, in URINARY INCONTINENCE, in MOTION SICKNESS, as an antispasmodic, and as a mydriatic and cycloplegic.
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
The procedure of presenting the conditioned stimulus without REINFORCEMENT to an organism previously conditioned. It refers also to the diminution of a conditioned response resulting from this procedure.
Induction of a stress reaction in experimental subjects by means of an electrical shock; applies to either convulsive or non-convulsive states.
Neural tracts connecting one part of the nervous system with another.
Behavioral manifestations of cerebral dominance in which there is preferential use and superior functioning of either the left or the right side, as in the preferred use of the right hand or right foot.
A member of the tumor necrosis factor receptor superfamily found on most T-LYMPHOCYTES. Activation of the receptor by CD70 ANTIGEN results in the increased proliferation of CD4-POSITIVE T-LYMPHOCYTES and CD8-POSITIVE T-LYMPHOCYTES. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
A meshlike structure composed of interconnecting nerve cells that are separated at the synaptic junction or joined to one another by cytoplasmic processes. In invertebrates, for example, the nerve net allows nerve impulses to spread over a wide area of the net because synapses can pass information in any direction.
A functional relationship between psychological phenomena of such nature that the presence of one tends to evoke the other; also, the process by which such a relationship is established.
The ability to detect scents or odors, such as the function of OLFACTORY RECEPTOR NEURONS.
Learning that is manifested in the ability to respond differentially to various stimuli.
The detailed examination of observable activity or behavior associated with the execution or completion of a required function or unit of work.
The volatile portions of substances perceptible by the sense of smell. (Grant & Hackh's Chemical Dictionary, 5th ed)
Upper central part of the cerebral hemisphere. It is located posterior to central sulcus, anterior to the OCCIPITAL LOBE, and superior to the TEMPORAL LOBES.
The part of the cerebral hemisphere anterior to the central sulcus, and anterior and superior to the lateral sulcus.
A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.
The relationships between symbols and their meanings.
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
An antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.
Includes both producing and responding to words, either written or spoken.
The thin layer of GRAY MATTER on the surface of the CEREBRAL HEMISPHERES that develops from the TELENCEPHALON and folds into gyri and sulchi. It reaches its highest development in humans and is responsible for intellectual faculties and higher mental functions.
Theoretical representations that simulate the behavior or activity of the neurological system, processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
Tests designed to measure intellectual functioning in children and adults.
Learning to make a series of responses in exact order.
Lymphoid cells concerned with humoral immunity. They are short-lived cells resembling bursa-derived lymphocytes of birds in their production of immunoglobulin upon appropriate stimulation.
Cerebral cortex region on the medial aspect of the PARAHIPPOCAMPAL GYRUS, immediately caudal to the OLFACTORY CORTEX of the uncus. The entorhinal cortex is the origin of the major neural fiber system afferent to the HIPPOCAMPAL FORMATION, the so-called PERFORANT PATHWAY.
Recording of electric currents developed in the brain by means of electrodes applied to the scalp, to the surface of the brain, or placed within the substance of the brain.
Differential response to different stimuli.
High-molecular weight glycoproteins uniquely expressed on the surface of LEUKOCYTES and their hemopoietic progenitors. They contain a cytoplasmic protein tyrosine phosphatase activity which plays a role in intracellular signaling from the CELL SURFACE RECEPTORS. The CD45 antigens occur as multiple isoforms that result from alternative mRNA splicing and differential usage of three exons.
Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
Process of classifying cells of the immune system based on structural and functional differences. The process is commonly used to analyze and sort T-lymphocytes into subsets based on CD antigens by the technique of flow cytometry.
A new pattern of perceptual or ideational material derived from past experience.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
Drugs used to specifically facilitate learning or memory, particularly to prevent the cognitive deficits associated with dementias. These drugs act by a variety of mechanisms. While no potent nootropic drugs have yet been accepted for general use, several are being actively investigated.
The process of discovering or asserting an objective or intrinsic relation between two objects or concepts; a faculty or power that enables a person to make judgments; the process of bringing to light and asserting the implicit meaning of a concept; a critical evaluation of a person or situation.
One of four subsections of the hippocampus described by Lorente de No, located furthest from the DENTATE GYRUS.
Brain waves characterized by a frequency of 4-7 Hz, usually observed in the temporal lobes when the individual is awake, but relaxed and sleepy.
A classification of B-lymphocytes based on structurally or functionally different populations of cells.
Any immunization following a primary immunization and involving exposure to the same or a closely related antigen.
The type species of ARENAVIRUS, part of the Old World Arenaviruses (ARENAVIRUSES, OLD WORLD), producing a silent infection in house and laboratory mice. In humans, infection with LCMV can be inapparent, or can present with an influenza-like illness, a benign aseptic meningitis, or a severe meningoencephalomyelitis. The virus can also infect monkeys, dogs, field mice, guinea pigs, and hamsters, the latter an epidemiologically important host.
A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity.
A species of the genus MACACA inhabiting India, China, and other parts of Asia. The species is used extensively in biomedical research and adapts very well to living with humans.
Theoretical representations that simulate psychological processes and/or social processes. These include the use of mathematical equations, computers, and other electronic equipment.
Electrical responses recorded from nerve, muscle, SENSORY RECEPTOR, or area of the CENTRAL NERVOUS SYSTEM following stimulation. They range from less than a microvolt to several microvolts. The evoked potential can be auditory (EVOKED POTENTIALS, AUDITORY), somatosensory (EVOKED POTENTIALS, SOMATOSENSORY), visual (EVOKED POTENTIALS, VISUAL), or motor (EVOKED POTENTIALS, MOTOR), or other modalities that have been reported.
Form of passive immunization where previously sensitized immunologic agents (cells or serum) are transferred to non-immune recipients. When transfer of cells is used as a therapy for the treatment of neoplasms, it is called adoptive immunotherapy (IMMUNOTHERAPY, ADOPTIVE).
Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.
The disappearance of responsiveness to a repeated stimulation. It does not include drug habituation.
Cortical vigilance or readiness of tone, presumed to be in response to sensory stimulation via the reticular activating system.
The observable response of a man or animal to a situation.
Use of sound to elicit a response in the nervous system.
Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.
Learning situations in which the sequence responses of the subject are instrumental in producing reinforcement. When the correct response occurs, which involves the selection from among a repertoire of responses, the subject is immediately reinforced.
Lists of words to which individuals are asked to respond ascertaining the conceptual meaning held by the individual.
The physical activity of a human or an animal as a behavioral phenomenon.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
The anterior portion of the head that includes the skin, muscles, and structures of the forehead, eyes, nose, mouth, cheeks, and jaw.
A readily reversible suspension of sensorimotor interaction with the environment, usually associated with recumbency and immobility.
Conceptual functions or thinking in all its forms.
A subsection of the hippocampus, described by Lorente de No, that is located between the HIPPOCAMPUS CA2 FIELD and the DENTATE GYRUS.
A type of procedural memory manifested as a change in the ability to identify an item as a result of a previous encounter with the item or stimuli.
Awareness of oneself in relation to time, place and person.
Inbred BALB/c mice are a strain of laboratory mice that have been selectively bred to be genetically identical to each other, making them useful for scientific research and experiments due to their consistent genetic background and predictable responses to various stimuli or treatments.
Devices capable of receiving data, retaining data for an indefinite or finite period of time, and supplying data upon demand.
GRAY MATTER situated above the GYRUS HIPPOCAMPI. It is composed of three layers. The molecular layer is continuous with the HIPPOCAMPUS in the hippocampal fissure. The granular layer consists of closely arranged spherical or oval neurons, called GRANULE CELLS, whose AXONS pass through the polymorphic layer ending on the DENDRITES of PYRAMIDAL CELLS in the hippocampus.
Those psychological characteristics which differentiate individuals from one another.
The ability to learn and to deal with new situations and to deal effectively with tasks involving abstractions.
A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
A genus of dextrally coiled freshwater snails that includes some species of importance as intermediate hosts of parasitic flukes.
The interference with or prevention of a behavioral or verbal response even though the stimulus for that response is present; in psychoanalysis the unconscious restraining of an instinctual process.
An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.
Antigenic determinants recognized and bound by the T-cell receptor. Epitopes recognized by the T-cell receptor are often located in the inner, unexposed side of the antigen, and become accessible to the T-cell receptors after proteolytic processing of the antigen.
The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.
Performance of an act one or more times, with a view to its fixation or improvement; any performance of an act or behavior that leads to learning.
The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.
Cytokine that stimulates the proliferation of T-LYMPHOCYTES and shares biological activities with IL-2. IL-15 also can induce proliferation and differentiation of B-LYMPHOCYTES.
Simulation of symptoms of illness or injury with intent to deceive in order to obtain a goal, e.g., a claim of physical illness to avoid jury duty.
A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the temporal lobe, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic (i.e., related to an identified disease process or lesion). (From Adams et al., Principles of Neurology, 6th ed, p321)
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
A form of meningitis caused by LYMPHOCYTIC CHORIOMENINGITIS VIRUS. MICE and other rodents serve as the natural hosts, and infection in humans usually occurs through inhalation or ingestion of infectious particles. Clinical manifestations include an influenza-like syndrome followed by stiff neck, alterations of mentation, ATAXIA, and incontinence. Maternal infections may result in fetal malformations and injury, including neonatal HYDROCEPHALUS, aqueductal stenosis, CHORIORETINITIS, and MICROCEPHALY. (From Joynt, Clinical Neurology, 1996, Ch26, pp1-3)
A prodromal phase of cognitive decline that may precede the emergence of ALZHEIMER DISEASE and other dementias. It may include impairment of cognition, such as impairments in language, visuospatial awareness, ATTENTION and MEMORY.
The number of LYMPHOCYTES per unit volume of BLOOD.
The process by which the nature and meaning of olfactory stimuli, such as odors, are recognized and interpreted by the brain.
Standardized tests designed to measure abilities, as in intelligence, aptitude, and achievement tests, or to evaluate personality traits.
Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins.
Spiny processes on DENDRITES, each of which receives excitatory input from one nerve ending (NERVE ENDINGS). They are commonly found on PURKINJE CELLS and PYRAMIDAL CELLS.
A neurosurgical procedure that removes the anterior TEMPORAL LOBE including the medial temporal structures of CEREBRAL CORTEX; AMYGDALA; HIPPOCAMPUS; and the adjacent PARAHIPPOCAMPAL GYRUS. This procedure is generally used for the treatment of intractable temporal epilepsy (EPILEPSY, TEMPORAL LOBE).
Heavily myelinated fiber bundle of the TELENCEPHALON projecting from the hippocampal formation to the HYPOTHALAMUS. Some authorities consider the fornix part of the LIMBIC SYSTEM. The fimbria starts as a flattened band of axons arising from the subiculum and HIPPOCAMPUS, which then thickens to form the fornix.
A learning situation involving more than one alternative from which a selection is made in order to attain a specific goal.
Animal searching behavior. The variable introductory phase of an instinctive behavior pattern or sequence, e.g., looking for food, or sequential courtship patterns prior to mating.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
A verbal or nonverbal means of communicating ideas or feelings.
A group of nerve cells in the SUBSTANTIA INNOMINATA that has wide projections to the NEOCORTEX and is rich in ACETYLCHOLINE and CHOLINE ACETYLTRANSFERASE. In PARKINSON DISEASE and ALZHEIMER DISEASE the nucleus undergoes degeneration.
An acquired cognitive disorder characterized by inattentiveness and the inability to form short term memories. This disorder is frequently associated with chronic ALCOHOLISM; but it may also result from dietary deficiencies; CRANIOCEREBRAL TRAUMA; NEOPLASMS; CEREBROVASCULAR DISORDERS; ENCEPHALITIS; EPILEPSY; and other conditions. (Adams et al., Principles of Neurology, 6th ed, p1139)
Standardized tests that measure the present general ability or aptitude for intellectual performance.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Infections with bacteria of the genus LISTERIA.
Set of nerve fibers conducting impulses from olfactory receptors to the cerebral cortex. It includes the OLFACTORY NERVE; OLFACTORY BULB; OLFACTORY TRACT; OLFACTORY TUBERCLE; ANTERIOR PERFORATED SUBSTANCE; and OLFACTORY CORTEX.
'Reading' in a medical context often refers to the act or process of a person interpreting and comprehending written or printed symbols, such as letters or words, for the purpose of deriving information or meaning from them.

Physiological characteristics of capacity constraints in working memory as revealed by functional MRI. (1/8569)

A fundamental characteristic of working memory is that its capacity to handle information is limited. While there have been many brain mapping studies of working memory, the physiological basis of its capacity limitation has not been explained. We identified characteristics of working memory capacity using functional magnetic resonance imaging (fMRI) in healthy subjects. Working memory capacity was studied using a parametric 'n-back' working memory task involving increasing cognitive load and ultimately decreasing task performance. Loci within dorsolateral prefrontal cortex (DLPFC) evinced exclusively an 'inverted-U' shaped neurophysiological response from lowest to highest load, consistent with a capacity-constrained response. Regions outside of DLPFC, in contrast, were more heterogeneous in response and often showed early plateau or continuously increasing responses, which did not reflect capacity constraints. However, sporadic loci, including in the premotor cortex, thalamus and superior parietal lobule, also demonstrated putative capacity-constrained responses, perhaps arising as an upstream effect of DLPFC limitations or as part of a broader network-wide capacity limitation. These results demonstrate that regionally specific nodes within the working memory network are capacity-constrained in the physiological domain, providing a missing link in current explorations of the capacity characteristics of working memory.  (+info)

Neural changes after operant conditioning of the aerial respiratory behavior in Lymnaea stagnalis. (2/8569)

In this study, we demonstrate neural changes that occurred during operant conditioning of the aerial respiratory behavior of Lymnaea stagnalis. Aerial respiration in Lymnaea occurs at the water interface and is achieved by opening and closing movements of its respiratory orifice, the pneumostome. This behavior is controlled by a central pattern generator (CPG), the neurons of which, as well as the motoneurons innervating the pneumostome, have previously been identified and their synaptic connections well characterized. The respiratory behavior was operantly conditioned by applying a mechanical stimulus to the open pneumostome whenever the animal attempted to breathe. This negative reinforcement to the open pneumostome resulted in its immediate closure and a significant reduction in the overall respiratory activity. Electrophysiological recordings from the isolated CNSs after operant conditioning showed that the spontaneous patterned respiratory activity of the CPG neurons was significantly reduced. This included reduced spontaneous activity of the CPG interneuron involved in pneumostome opening (input 3 interneuron) and a reduced frequency of spontaneous tonic activity of the CPG interneuron [right pedal dorsal 1 (RPeD1)]. The ability to trigger the patterned respiratory activity by electrical stimulation of RPeD1 was also significantly reduced after operant conditioning. This study therefore demonstrates significant changes within a CPG that are associated with changes in a rhythmic homeostatic behavior after operant conditioning.  (+info)

Differential spatial memory impairment after right temporal lobectomy demonstrated using temporal titration. (3/8569)

In this study a temporal titration method to explore the extent to which spatial memory is differentially impaired following right temporal lobectomy was employed. The spatial and non-spatial memory of 19 left and 19 right temporal lobectomy (TL) patients was compared with that of 16 normal controls. The subjects studied an array of 16 toy objects and were subsequently tested for object recall, object recognition and memory for the location of the objects. By systematically varying the retention intervals for each group, it was possible to match all three groups on object recall at sub-ceiling levels. When memory for the position of the objects was assessed at equivalent delays, the right TL group revealed disrupted spatial memory, compared with both left TL and control groups (P < 0.05). MRI was used to quantify the extent of temporal lobe resection in the two groups and a significant correlation between hippocampal removal and both recall of spatial location and object name recall in the right TL group only was shown. These data support the notion of a selective (but not exclusive) spatial memory impairment associated with right temporal lobe damage that is related to the integrity of the hippocampal functioning.  (+info)

Object location learning and non-spatial working memory of patients with Parkinson's disease may be preserved in "real life" situations. (4/8569)

The presence of a spatial memory deficit in Parkinson's disease (PD) is still a matter of discussion. Nineteen PD patients and 16 controls were given two spatial tests and a non-spatial task. First, the subject was led into a room containing 4 objects and had 10 s to memorize their location. After being led outside, the subject had to place icons representing the objects on a map of the room. Differences between the real and estimated locations were evaluated. Afterwards, the subject had to choose a map showing the correct arrangement of objects from 4 alternatives. Locations of some objects were changed before the second test. The subject had 10 s to detect these changes. One point was given for each change or its absence detected. In the non-spatial working memory task, 8 cards of different shapes were used. The subject had to select a different card each time while the cards were shuffled between choices. Errors consisted of selecting previously chosen cards. The means of the above measures for both groups were compared. Absence of any significant differences suggests that PD patients perform well in "real life" memory tests in contrast to similar computerized tests.  (+info)

The predictive value of changes in effective connectivity for human learning. (5/8569)

During learning, neural responses decrease over repeated exposure to identical stimuli. This repetition suppression is thought to reflect a progressive optimization of neuronal responses elicited by the task. Functional magnetic resonance imaging was used to study the neural basis of associative learning of visual objects and their locations. As expected, activation in specialized cortical areas decreased with time. However, with path analysis it was shown that, in parallel to this adaptation, increases in effective connectivity occurred between distinct cortical systems specialized for spatial and object processing. The time course of these plastic changes was highly correlated with individual learning performance, suggesting that interactions between brain areas underlie associative learning.  (+info)

Crossmodal associative memory representations in rodent orbitofrontal cortex. (6/8569)

Firing patterns of neurons in the orbitofrontal cortex (OF) were analyzed in rats trained to perform a task that encouraged incidental associations between distinct odors and the places where their occurrence was detected. Many of the neurons fired differentially when the animals were at a particular location or sampled particular odors. Furthermore, a substantial fraction of the cells exhibited odor-specific firing patterns prior to odor presentation, when the animal arrived at a location associated with that odor. These findings suggest that neurons in the OF encode cross-modal associations between odors and locations within long-term memory.  (+info)

Episodic memory in transient global amnesia: encoding, storage, or retrieval deficit? (7/8569)

OBJECTIVES: To assess episodic memory (especially anterograde amnesia) during the acute phase of transient global amnesia to differentiate an encoding, a storage, or a retrieval deficit. METHODS: In three patients, whose amnestic episode fulfilled all current criteria for transient global amnesia, a neuropsychological protocol was administered which included a word learning task derived from the Grober and Buschke's procedure. RESULTS: In one patient, the results suggested an encoding deficit, and in two others, a storage deficit. CONCLUSIONS: The encoding/storage impairment concerning anterograde amnesia documented in our patients stands in clear contrast with the impairment in retrieval which must underly the retrograde amnesia that also characterises transient global amnesia. This dissociation in turn favours the idea of a functional independence among the cognitive mechanisms that subserve episodic memory.  (+info)

Executive function in depression: the role of performance strategies in aiding depressed and non-depressed participants. (8/8569)

OBJECTIVES: Depression has been found to be associated with dysfunction in executive processes, whereas relatively automatic processes are thought to remain intact. Failure to generate or implement adequate performance strategies has been postulated in depressed participants. The present study investigated spontaneous strategy usage in depressed and control participants, and the effectiveness of providing a hint about performance strategies. METHODS: Unipolar depressed participants were compared with matched healthy controls on three tasks sensitive to executive function: memory for categorised words, response suppression, and multiple scheduling. Participants in each group were randomly allocated to strategy aid and no strategy aid conditions. Those in the strategy aid condition were given a hint about the use of an appropriate performance strategy for each task, in addition to the standard instructions given to those in the no strategy aid condition. RESULTS: Depressed participants performed worse than controls on each of the three tasks, and were found to use appropriate performance strategies less often. Provision of strategy hints increased the use of performance strategies in two of the three tasks, memory for categorised words, and response suppression, but did not significantly improve overall performance for either group. CONCLUSIONS: The findings were consistent with the view that depressed participants fail to use appropriate performance strategies spontaneously to the same extent as controls. However, provision of information alone does not seem to be an adequate means of enhancing performance. The role of performance strategies in cognitive impairment in depression is discussed, both in terms of initiating use of such strategies and carrying these out efficiently.  (+info)

In the context of medical and clinical neuroscience, memory is defined as the brain's ability to encode, store, retain, and recall information or experiences. Memory is a complex cognitive process that involves several interconnected regions of the brain and can be categorized into different types based on various factors such as duration and the nature of the information being remembered.

The major types of memory include:

1. Sensory memory: The shortest form of memory, responsible for holding incoming sensory information for a brief period (less than a second to several seconds) before it is either transferred to short-term memory or discarded.
2. Short-term memory (also called working memory): A temporary storage system that allows the brain to hold and manipulate information for approximately 20-30 seconds, although this duration can be extended through rehearsal strategies. Short-term memory has a limited capacity, typically thought to be around 7±2 items.
3. Long-term memory: The memory system responsible for storing large amounts of information over extended periods, ranging from minutes to a lifetime. Long-term memory has a much larger capacity compared to short-term memory and is divided into two main categories: explicit (declarative) memory and implicit (non-declarative) memory.

Explicit (declarative) memory can be further divided into episodic memory, which involves the recollection of specific events or episodes, including their temporal and spatial contexts, and semantic memory, which refers to the storage and retrieval of general knowledge, facts, concepts, and vocabulary, independent of personal experience or context.

Implicit (non-declarative) memory encompasses various forms of learning that do not require conscious awareness or intention, such as procedural memory (skills and habits), priming (facilitated processing of related stimuli), classical conditioning (associative learning), and habituation (reduced responsiveness to repeated stimuli).

Memory is a crucial aspect of human cognition and plays a significant role in various aspects of daily life, including learning, problem-solving, decision-making, social interactions, and personal identity. Memory dysfunction can result from various neurological and psychiatric conditions, such as dementia, Alzheimer's disease, stroke, traumatic brain injury, and depression.

Memory disorders are a category of cognitive impairments that affect an individual's ability to acquire, store, retain, and retrieve memories. These disorders can be caused by various underlying medical conditions, including neurological disorders, psychiatric illnesses, substance abuse, or even normal aging processes. Some common memory disorders include:

1. Alzheimer's disease: A progressive neurodegenerative disorder that primarily affects older adults and is characterized by a decline in cognitive abilities, including memory, language, problem-solving, and decision-making skills.
2. Dementia: A broader term used to describe a group of symptoms associated with a decline in cognitive function severe enough to interfere with daily life. Alzheimer's disease is the most common cause of dementia, but other causes include vascular dementia, Lewy body dementia, and frontotemporal dementia.
3. Amnesia: A memory disorder characterized by difficulties in forming new memories or recalling previously learned information due to brain damage or disease. Amnesia can be temporary or permanent and may result from head trauma, stroke, infection, or substance abuse.
4. Mild cognitive impairment (MCI): A condition where an individual experiences mild but noticeable memory or cognitive difficulties that are greater than expected for their age and education level. While some individuals with MCI may progress to dementia, others may remain stable or even improve over time.
5. Korsakoff's syndrome: A memory disorder often caused by alcohol abuse and thiamine deficiency, characterized by severe short-term memory loss, confabulation (making up stories to fill in memory gaps), and disorientation.

It is essential to consult a healthcare professional if you or someone you know experiences persistent memory difficulties, as early diagnosis and intervention can help manage symptoms and improve quality of life.

Short-term memory, also known as primary or active memory, is the system responsible for holding and processing limited amounts of information for brief periods of time, typically on the order of seconds to minutes. It has a capacity of around 7±2 items, as suggested by George Miller's "magic number" theory. Short-term memory allows us to retain and manipulate information temporarily while we are using it, such as remembering a phone number while dialing or following a set of instructions. Information in short-term memory can be maintained through rehearsal, which is the conscious repetition of the information. Over time, if the information is not transferred to long-term memory through consolidation processes, it will be forgotten.

Immunologic memory, also known as adaptive immunity, refers to the ability of the immune system to recognize and mount a more rapid and effective response upon subsequent exposure to a pathogen or antigen that it has encountered before. This is a key feature of the vertebrate immune system and allows for long-term protection against infectious diseases.

Immunologic memory is mediated by specialized cells called memory T cells and B cells, which are produced during the initial response to an infection or immunization. These cells persist in the body after the pathogen has been cleared and can quickly respond to future encounters with the same or similar antigens. This rapid response leads to a more effective and efficient elimination of the pathogen, resulting in fewer symptoms and reduced severity of disease.

Immunologic memory is the basis for vaccines, which work by exposing the immune system to a harmless form of a pathogen or its components, inducing an initial response and generating memory cells that provide long-term protection against future infections.

Long-term memory is the cognitive system that stores information for extended periods of time, ranging from hours to a lifetime. It is responsible for the retention and retrieval of factual knowledge (semantic memory), personal experiences (episodic memory), skills (procedural memory), and other types of information. Long-term memory has a larger capacity compared to short-term or working memory, and its contents are more resistant to interference and forgetting. The formation and consolidation of long-term memories often involve the hippocampus and other medial temporal lobe structures, as well as widespread cortical networks.

Episodic memory is a type of declarative (explicit) memory that involves the ability to recall and mentally reexperience specific events or episodes, including their temporal and spatial contexts. It is the memory for particular events or episodes that are embedded in a personal autobiographical timeline, along with the details of what happened, where it happened, who was involved, and when it happened. Episodic memories are often formed through conscious effort and can be voluntarily retrieved. They are susceptible to interference and decay over time, making them less reliable than other types of memory.

"Mental recall," also known as "memory recall," refers to the ability to retrieve or bring information from your memory storage into your conscious mind, so you can think about, use, or apply it. This process involves accessing and retrieving stored memories in response to certain cues or prompts. It is a fundamental cognitive function that allows individuals to remember and recognize people, places, events, facts, and experiences.

In the context of medical terminology, mental recall may be used to assess an individual's cognitive abilities, particularly in relation to memory function. Impairments in memory recall can be indicative of various neurological or psychological conditions, such as dementia, Alzheimer's disease, or amnesia.

Maze learning is not a medical term per se, but it is a concept that is often used in the field of neuroscience and psychology. It refers to the process by which an animal or human learns to navigate through a complex environment, such as a maze, in order to find its way to a goal or target.

Maze learning involves several cognitive processes, including spatial memory, learning, and problem-solving. As animals or humans navigate through the maze, they encode information about the location of the goal and the various landmarks within the environment. This information is then used to form a cognitive map that allows them to navigate more efficiently in subsequent trials.

Maze learning has been widely used as a tool for studying learning and memory processes in both animals and humans. For example, researchers may use maze learning tasks to investigate the effects of brain damage or disease on cognitive function, or to evaluate the efficacy of various drugs or interventions for improving cognitive performance.

Neuropsychological tests are a type of psychological assessment that measures cognitive functions, such as attention, memory, language, problem-solving, and perception. These tests are used to help diagnose and understand the cognitive impact of neurological conditions, including dementia, traumatic brain injury, stroke, Parkinson's disease, and other disorders that affect the brain.

The tests are typically administered by a trained neuropsychologist and can take several hours to complete. They may involve paper-and-pencil tasks, computerized tasks, or interactive activities. The results of the tests are compared to normative data to help identify any areas of cognitive weakness or strength.

Neuropsychological testing can provide valuable information for treatment planning, rehabilitation, and assessing response to treatment. It can also be used in research to better understand the neural basis of cognition and the impact of neurological conditions on cognitive function.

The hippocampus is a complex, curved formation in the brain that resembles a seahorse (hence its name, from the Greek word "hippos" meaning horse and "kampos" meaning sea monster). It's part of the limbic system and plays crucial roles in the formation of memories, particularly long-term ones.

This region is involved in spatial navigation and cognitive maps, allowing us to recognize locations and remember how to get to them. Additionally, it's one of the first areas affected by Alzheimer's disease, which often results in memory loss as an early symptom.

Anatomically, it consists of two main parts: the Ammon's horn (or cornu ammonis) and the dentate gyrus. These structures are made up of distinct types of neurons that contribute to different aspects of learning and memory.

In the context of medicine and healthcare, learning is often discussed in relation to learning abilities or disabilities that may impact an individual's capacity to acquire, process, retain, and apply new information or skills. Learning can be defined as the process of acquiring knowledge, understanding, behaviors, and skills through experience, instruction, or observation.

Learning disorders, also known as learning disabilities, are a type of neurodevelopmental disorder that affects an individual's ability to learn and process information in one or more areas, such as reading, writing, mathematics, or reasoning. These disorders are not related to intelligence or motivation but rather result from differences in the way the brain processes information.

It is important to note that learning can also be influenced by various factors, including age, cognitive abilities, physical and mental health status, cultural background, and educational experiences. Therefore, a comprehensive assessment of an individual's learning abilities and needs should take into account these various factors to provide appropriate support and interventions.

Association learning, also known as associative learning, is a type of learning in which an individual learns to associate two stimuli or a response with a particular outcome. This can occur through classical conditioning or operant conditioning.

In classical conditioning, first described by Ivan Pavlov, an initially neutral stimulus (the conditioned stimulus) is repeatedly paired with a biologically significant stimulus (the unconditioned stimulus), until the conditioned stimulus elicits a response (the conditioned response) similar to that of the unconditioned stimulus. For example, a dog may learn to salivate at the sound of a bell if the bell is repeatedly rung just before it is fed.

In operant conditioning, described by B.F. Skinner, behavior is modified by its consequences, with desired behaviors being reinforced and undesired behaviors being punished. For example, a child may learn to put their toys away if they are given a reward for doing so.

Association learning is an important mechanism in the acquisition of many types of knowledge and skills, and it plays a key role in the development and modification of behavior.

Amnesia is a condition characterized by memory loss, which can be temporary or permanent. It may result from brain damage or disease, and it can affect various aspects of memory, such as the ability to recall past events (retrograde amnesia), the ability to form new memories (anterograde amnesia), or both. Amnesia can also affect a person's sense of identity and their ability to learn new skills.

There are several types of amnesia, including:

1. Anterograde amnesia: This type of amnesia affects the ability to form new memories after an injury or trauma. People with anterograde amnesia may have difficulty learning new information and remembering recent events.
2. Retrograde amnesia: Retrograde amnesia affects the ability to recall memories that were formed before an injury or trauma. People with retrograde amnesia may have trouble remembering events, people, or facts from their past.
3. Transient global amnesia: This is a temporary form of amnesia that usually lasts for less than 24 hours. It is often caused by a lack of blood flow to the brain, and it can be triggered by emotional stress, physical exertion, or other factors.
4. Korsakoff's syndrome: This is a type of amnesia that is caused by alcohol abuse and malnutrition. It is characterized by severe memory loss, confusion, and disorientation.
5. Dissociative amnesia: This type of amnesia is caused by psychological factors, such as trauma or stress. People with dissociative amnesia may have trouble remembering important personal information or events that are emotionally charged.

The treatment for amnesia depends on the underlying cause. In some cases, memory may improve over time, while in other cases, it may be permanent. Treatment may involve medication, therapy, or rehabilitation to help people with amnesia cope with their memory loss and develop new skills to compensate for their memory impairments.

Verbal learning is a type of learning that involves the acquisition, processing, and retrieval of information presented in a verbal or written form. It is often assessed through tasks such as list learning, where an individual is asked to remember a list of words or sentences after a single presentation or multiple repetitions. Verbal learning is an important aspect of cognitive functioning and is commonly evaluated in neuropsychological assessments to help identify any memory or learning impairments.

Fear is a basic human emotion that is typically characterized by a strong feeling of anxiety, apprehension, or distress in response to a perceived threat or danger. It is a natural and adaptive response that helps individuals identify and respond to potential dangers in their environment, and it can manifest as physical, emotional, and cognitive symptoms.

Physical symptoms of fear may include increased heart rate, rapid breathing, sweating, trembling, and muscle tension. Emotional symptoms may include feelings of anxiety, worry, or panic, while cognitive symptoms may include difficulty concentrating, racing thoughts, and intrusive thoughts about the perceived threat.

Fear can be a normal and adaptive response to real dangers, but it can also become excessive or irrational in some cases, leading to phobias, anxiety disorders, and other mental health conditions. In these cases, professional help may be necessary to manage and overcome the fear.

I'm sorry for any confusion, but "spatial behavior" is not a term that has a specific medical definition. It is a concept that is used in various fields, including psychology, neuroscience, and robotics, to refer to the way that organisms or machines navigate and interact with their environment based on spatial relationships and coordinates.

In a broader context, "spatial behavior" can sometimes be used to describe certain aspects of human behavior related to how people move and interact within spaces, such as in architecture, urban planning, or ergonomics. However, it is not a term that is typically used in medical diagnoses or treatments.

If you have any specific questions about a concept related to medicine or health, I would be happy to try to help answer them for you!

Cognition refers to the mental processes involved in acquiring, processing, and utilizing information. These processes include perception, attention, memory, language, problem-solving, and decision-making. Cognitive functions allow us to interact with our environment, understand and respond to stimuli, learn new skills, and remember experiences.

In a medical context, cognitive function is often assessed as part of a neurological or psychiatric evaluation. Impairments in cognition can be caused by various factors, such as brain injury, neurodegenerative diseases (e.g., Alzheimer's disease), infections, toxins, and mental health conditions. Assessing cognitive function helps healthcare professionals diagnose conditions, monitor disease progression, and develop treatment plans.

Avoidance learning is a type of conditioning in which an individual learns to act in a certain way to avoid experiencing an unpleasant or aversive stimulus. It is a form of learning that occurs when an organism changes its behavior to avoid a negative outcome or situation. This can be seen in both animals and humans, and it is often studied in the field of psychology and neuroscience.

In avoidance learning, the individual learns to associate a particular cue or stimulus with the unpleasant experience. Over time, they learn to perform an action to escape or avoid the cue, thereby preventing the negative outcome from occurring. For example, if a rat receives an electric shock every time it hears a certain tone, it may eventually learn to press a lever to turn off the tone and avoid the shock.

Avoidance learning can be adaptive in some situations, as it allows individuals to avoid dangerous or harmful stimuli. However, it can also become maladaptive if it leads to excessive fear or anxiety, or if it interferes with an individual's ability to function in daily life. For example, a person who has been attacked may develop a phobia of public places and avoid them altogether, even though this limits their ability to engage in social activities and live a normal life.

In summary, avoidance learning is a type of conditioning in which an individual learns to act in a certain way to avoid experiencing an unpleasant or aversive stimulus. It can be adaptive in some situations but can also become maladaptive if it leads to excessive fear or anxiety or interferes with daily functioning.

Reaction time, in the context of medicine and physiology, refers to the time period between the presentation of a stimulus and the subsequent initiation of a response. This complex process involves the central nervous system, particularly the brain, which perceives the stimulus, processes it, and then sends signals to the appropriate muscles or glands to react.

There are different types of reaction times, including simple reaction time (responding to a single, expected stimulus) and choice reaction time (choosing an appropriate response from multiple possibilities). These measures can be used in clinical settings to assess various aspects of neurological function, such as cognitive processing speed, motor control, and alertness.

However, it is important to note that reaction times can be influenced by several factors, including age, fatigue, attention, and the use of certain medications or substances.

CD8-positive T-lymphocytes, also known as CD8+ T cells or cytotoxic T cells, are a type of white blood cell that plays a crucial role in the adaptive immune system. They are named after the CD8 molecule found on their surface, which is a protein involved in cell signaling and recognition.

CD8+ T cells are primarily responsible for identifying and destroying virus-infected cells or cancerous cells. When activated, they release cytotoxic granules that contain enzymes capable of inducing apoptosis (programmed cell death) in the target cells. They also produce cytokines such as interferon-gamma, which can help coordinate the immune response and activate other immune cells.

CD8+ T cells are generated in the thymus gland and are a type of T cell, which is a lymphocyte that matures in the thymus and plays a central role in cell-mediated immunity. They recognize and respond to specific antigens presented on the surface of infected or cancerous cells in conjunction with major histocompatibility complex (MHC) class I molecules.

Overall, CD8+ T cells are an essential component of the immune system's defense against viral infections and cancer.

Medical Definition:

Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic imaging technique that uses a strong magnetic field and radio waves to create detailed cross-sectional or three-dimensional images of the internal structures of the body. The patient lies within a large, cylindrical magnet, and the scanner detects changes in the direction of the magnetic field caused by protons in the body. These changes are then converted into detailed images that help medical professionals to diagnose and monitor various medical conditions, such as tumors, injuries, or diseases affecting the brain, spinal cord, heart, blood vessels, joints, and other internal organs. MRI does not use radiation like computed tomography (CT) scans.

Classical conditioning is a type of learning process that occurs when two stimuli are repeatedly paired together, leading to an association between them. This concept was first introduced by Ivan Pavlov, a Russian physiologist, in his studies on classical conditioning in the late 19th and early 20th centuries.

In classical conditioning, there are typically two types of stimuli involved: the unconditioned stimulus (US) and the neutral stimulus (NS). The US is a stimulus that naturally triggers a response, known as the unconditioned response (UR), in an organism. For example, food is an US that triggers salivation, which is the UR, in dogs.

The NS, on the other hand, is a stimulus that does not initially trigger any response in the organism. However, when the NS is repeatedly paired with the US, it becomes a conditioned stimulus (CS) and begins to elicit a conditioned response (CR). The CR is similar to the UR but is triggered by the CS instead of the US.

For example, if Pavlov repeatedly rang a bell (NS) just before presenting food (US) to a dog, the dog would eventually start salivating (CR) in response to the bell (CS) even when food was not presented. This is an example of classical conditioning.

Classical conditioning has been widely studied and is believed to play a role in various physiological processes, such as learning, memory, and emotion regulation. It has also been used in various applications, including behavioral therapy and advertising.

Analysis of Variance (ANOVA) is a statistical technique used to compare the means of two or more groups and determine whether there are any significant differences between them. It is a way to analyze the variance in a dataset to determine whether the variability between groups is greater than the variability within groups, which can indicate that the groups are significantly different from one another.

ANOVA is based on the concept of partitioning the total variance in a dataset into two components: variance due to differences between group means (also known as "between-group variance") and variance due to differences within each group (also known as "within-group variance"). By comparing these two sources of variance, ANOVA can help researchers determine whether any observed differences between groups are statistically significant, or whether they could have occurred by chance.

ANOVA is a widely used technique in many areas of research, including biology, psychology, engineering, and business. It is often used to compare the means of two or more experimental groups, such as a treatment group and a control group, to determine whether the treatment had a significant effect. ANOVA can also be used to compare the means of different populations or subgroups within a population, to identify any differences that may exist between them.

Cognitive disorders are a category of mental health disorders that primarily affect cognitive abilities including learning, memory, perception, and problem-solving. These disorders can be caused by various factors such as brain injury, degenerative diseases, infection, substance abuse, or developmental disabilities. Examples of cognitive disorders include dementia, amnesia, delirium, and intellectual disability. It's important to note that the specific definition and diagnostic criteria for cognitive disorders may vary depending on the medical source or classification system being used.

Psychomotor performance refers to the integration and coordination of mental processes (cognitive functions) with physical movements. It involves the ability to perform complex tasks that require both cognitive skills, such as thinking, remembering, and perceiving, and motor skills, such as gross and fine motor movements. Examples of psychomotor performances include driving a car, playing a musical instrument, or performing surgical procedures.

In a medical context, psychomotor performance is often used to assess an individual's ability to perform activities of daily living (ADLs) and instrumental activities of daily living (IADLs), such as bathing, dressing, cooking, cleaning, and managing medications. Deficits in psychomotor performance can be a sign of neurological or psychiatric disorders, such as dementia, Parkinson's disease, or depression.

Assessment of psychomotor performance may involve tests that measure reaction time, coordination, speed, precision, and accuracy of movements, as well as cognitive functions such as attention, memory, and problem-solving skills. These assessments can help healthcare professionals develop appropriate treatment plans and monitor the progression of diseases or the effectiveness of interventions.

'Animal behavior' refers to the actions or responses of animals to various stimuli, including their interactions with the environment and other individuals. It is the study of the actions of animals, whether they are instinctual, learned, or a combination of both. Animal behavior includes communication, mating, foraging, predator avoidance, and social organization, among other things. The scientific study of animal behavior is called ethology. This field seeks to understand the evolutionary basis for behaviors as well as their physiological and psychological mechanisms.

The brain is the central organ of the nervous system, responsible for receiving and processing sensory information, regulating vital functions, and controlling behavior, movement, and cognition. It is divided into several distinct regions, each with specific functions:

1. Cerebrum: The largest part of the brain, responsible for higher cognitive functions such as thinking, learning, memory, language, and perception. It is divided into two hemispheres, each controlling the opposite side of the body.
2. Cerebellum: Located at the back of the brain, it is responsible for coordinating muscle movements, maintaining balance, and fine-tuning motor skills.
3. Brainstem: Connects the cerebrum and cerebellum to the spinal cord, controlling vital functions such as breathing, heart rate, and blood pressure. It also serves as a relay center for sensory information and motor commands between the brain and the rest of the body.
4. Diencephalon: A region that includes the thalamus (a major sensory relay station) and hypothalamus (regulates hormones, temperature, hunger, thirst, and sleep).
5. Limbic system: A group of structures involved in emotional processing, memory formation, and motivation, including the hippocampus, amygdala, and cingulate gyrus.

The brain is composed of billions of interconnected neurons that communicate through electrical and chemical signals. It is protected by the skull and surrounded by three layers of membranes called meninges, as well as cerebrospinal fluid that provides cushioning and nutrients.

In a medical or psychological context, attention is the cognitive process of selectively concentrating on certain aspects of the environment while ignoring other things. It involves focusing mental resources on specific stimuli, sensory inputs, or internal thoughts while blocking out irrelevant distractions. Attention can be divided into different types, including:

1. Sustained attention: The ability to maintain focus on a task or stimulus over time.
2. Selective attention: The ability to concentrate on relevant stimuli while ignoring irrelevant ones.
3. Divided attention: The capacity to pay attention to multiple tasks or stimuli simultaneously.
4. Alternating attention: The skill of shifting focus between different tasks or stimuli as needed.

Deficits in attention are common symptoms of various neurological and psychiatric conditions, such as ADHD, dementia, depression, and anxiety disorders. Assessment of attention is an essential part of neuropsychological evaluations and can be measured using various tests and tasks.

The prefrontal cortex is the anterior (frontal) part of the frontal lobe in the brain, involved in higher-order cognitive processes such as planning complex cognitive behavior, personality expression, decision making, and moderating social behavior. It also plays a significant role in working memory and executive functions. The prefrontal cortex is divided into several subregions, each associated with specific cognitive and emotional functions. Damage to the prefrontal cortex can result in various impairments, including difficulties with planning, decision making, and social behavior regulation.

Brain mapping is a broad term that refers to the techniques used to understand the structure and function of the brain. It involves creating maps of the various cognitive, emotional, and behavioral processes in the brain by correlating these processes with physical locations or activities within the nervous system. Brain mapping can be accomplished through a variety of methods, including functional magnetic resonance imaging (fMRI), positron emission tomography (PET) scans, electroencephalography (EEG), and others. These techniques allow researchers to observe which areas of the brain are active during different tasks or thoughts, helping to shed light on how the brain processes information and contributes to our experiences and behaviors. Brain mapping is an important area of research in neuroscience, with potential applications in the diagnosis and treatment of neurological and psychiatric disorders.

In the context of medicine, "cues" generally refer to specific pieces of information or signals that can help healthcare professionals recognize and respond to a particular situation or condition. These cues can come in various forms, such as:

1. Physical examination findings: For example, a patient's abnormal heart rate or blood pressure reading during a physical exam may serve as a cue for the healthcare professional to investigate further.
2. Patient symptoms: A patient reporting chest pain, shortness of breath, or other concerning symptoms can act as a cue for a healthcare provider to consider potential diagnoses and develop an appropriate treatment plan.
3. Laboratory test results: Abnormal findings on laboratory tests, such as elevated blood glucose levels or abnormal liver function tests, may serve as cues for further evaluation and diagnosis.
4. Medical history information: A patient's medical history can provide valuable cues for healthcare professionals when assessing their current health status. For example, a history of smoking may increase the suspicion for chronic obstructive pulmonary disease (COPD) in a patient presenting with respiratory symptoms.
5. Behavioral or environmental cues: In some cases, behavioral or environmental factors can serve as cues for healthcare professionals to consider potential health risks. For instance, exposure to secondhand smoke or living in an area with high air pollution levels may increase the risk of developing respiratory conditions.

Overall, "cues" in a medical context are essential pieces of information that help healthcare professionals make informed decisions about patient care and treatment.

The amygdala is an almond-shaped group of nuclei located deep within the temporal lobe of the brain, specifically in the anterior portion of the temporal lobes and near the hippocampus. It forms a key component of the limbic system and plays a crucial role in processing emotions, particularly fear and anxiety. The amygdala is involved in the integration of sensory information with emotional responses, memory formation, and decision-making processes.

In response to emotionally charged stimuli, the amygdala can modulate various physiological functions, such as heart rate, blood pressure, and stress hormone release, via its connections to the hypothalamus and brainstem. Additionally, it contributes to social behaviors, including recognizing emotional facial expressions and responding appropriately to social cues. Dysfunctions in amygdala function have been implicated in several psychiatric and neurological conditions, such as anxiety disorders, depression, post-traumatic stress disorder (PTSD), and autism spectrum disorder (ASD).

The temporal lobe is one of the four main lobes of the cerebral cortex in the brain, located on each side of the head roughly level with the ears. It plays a major role in auditory processing, memory, and emotion. The temporal lobe contains several key structures including the primary auditory cortex, which is responsible for analyzing sounds, and the hippocampus, which is crucial for forming new memories. Damage to the temporal lobe can result in various neurological symptoms such as hearing loss, memory impairment, and changes in emotional behavior.

C57BL/6 (C57 Black 6) is an inbred strain of laboratory mouse that is widely used in biomedical research. The term "inbred" refers to a strain of animals where matings have been carried out between siblings or other closely related individuals for many generations, resulting in a population that is highly homozygous at most genetic loci.

The C57BL/6 strain was established in 1920 by crossing a female mouse from the dilute brown (DBA) strain with a male mouse from the black strain. The resulting offspring were then interbred for many generations to create the inbred C57BL/6 strain.

C57BL/6 mice are known for their robust health, longevity, and ease of handling, making them a popular choice for researchers. They have been used in a wide range of biomedical research areas, including studies of cancer, immunology, neuroscience, cardiovascular disease, and metabolism.

One of the most notable features of the C57BL/6 strain is its sensitivity to certain genetic modifications, such as the introduction of mutations that lead to obesity or impaired glucose tolerance. This has made it a valuable tool for studying the genetic basis of complex diseases and traits.

Overall, the C57BL/6 inbred mouse strain is an important model organism in biomedical research, providing a valuable resource for understanding the genetic and molecular mechanisms underlying human health and disease.

Repression in psychology is a defense mechanism that involves pushing unacceptable thoughts, feelings, or memories into the unconscious mind to avoid conscious awareness of them. This process occurs automatically and unconsciously as a way for individuals to cope with anxiety-provoking or distressing material. Repressed experiences may still influence behavior and emotions but are not directly accessible to consciousness. It's important to note that repression is different from suppression, which is a conscious and intentional effort to push away unwanted thoughts or feelings.

Photic stimulation is a medical term that refers to the exposure of the eyes to light, specifically repetitive pulses of light, which is used as a method in various research and clinical settings. In neuroscience, it's often used in studies related to vision, circadian rhythms, and brain function.

In a clinical context, photic stimulation is sometimes used in the diagnosis of certain medical conditions such as seizure disorders (like epilepsy). By observing the response of the brain to this light stimulus, doctors can gain valuable insights into the functioning of the brain and the presence of any neurological disorders.

However, it's important to note that photic stimulation should be conducted under the supervision of a trained healthcare professional, as improper use can potentially trigger seizures in individuals who are susceptible to them.

In the field of medicine, "time factors" refer to the duration of symptoms or time elapsed since the onset of a medical condition, which can have significant implications for diagnosis and treatment. Understanding time factors is crucial in determining the progression of a disease, evaluating the effectiveness of treatments, and making critical decisions regarding patient care.

For example, in stroke management, "time is brain," meaning that rapid intervention within a specific time frame (usually within 4.5 hours) is essential to administering tissue plasminogen activator (tPA), a clot-busting drug that can minimize brain damage and improve patient outcomes. Similarly, in trauma care, the "golden hour" concept emphasizes the importance of providing definitive care within the first 60 minutes after injury to increase survival rates and reduce morbidity.

Time factors also play a role in monitoring the progression of chronic conditions like diabetes or heart disease, where regular follow-ups and assessments help determine appropriate treatment adjustments and prevent complications. In infectious diseases, time factors are crucial for initiating antibiotic therapy and identifying potential outbreaks to control their spread.

Overall, "time factors" encompass the significance of recognizing and acting promptly in various medical scenarios to optimize patient outcomes and provide effective care.

Retrograde amnesia is a form of memory loss where an individual cannot recall information, events, or facts from their personal past before a specific point in time. This type of amnesia is caused by damage to the brain, often as a result of head injury, stroke, infection, or certain medical conditions. The extent and duration of retrograde amnesia can vary widely, depending on the severity and location of the brain injury. In some cases, memory function may return over time as the brain heals, while in other cases the memory loss may be permanent.

Neuronal plasticity, also known as neuroplasticity or neural plasticity, refers to the ability of the brain and nervous system to change and adapt as a result of experience, learning, injury, or disease. This can involve changes in the structure, organization, and function of neurons (nerve cells) and their connections (synapses) in the central and peripheral nervous systems.

Neuronal plasticity can take many forms, including:

* Synaptic plasticity: Changes in the strength or efficiency of synaptic connections between neurons. This can involve the formation, elimination, or modification of synapses.
* Neural circuit plasticity: Changes in the organization and connectivity of neural circuits, which are networks of interconnected neurons that process information.
* Structural plasticity: Changes in the physical structure of neurons, such as the growth or retraction of dendrites (branches that receive input from other neurons) or axons (projections that transmit signals to other neurons).
* Functional plasticity: Changes in the physiological properties of neurons, such as their excitability, responsiveness, or sensitivity to stimuli.

Neuronal plasticity is a fundamental property of the nervous system and plays a crucial role in many aspects of brain function, including learning, memory, perception, and cognition. It also contributes to the brain's ability to recover from injury or disease, such as stroke or traumatic brain injury.

CD4-positive T-lymphocytes, also known as CD4+ T cells or helper T cells, are a type of white blood cell that plays a crucial role in the immune response. They express the CD4 receptor on their surface and help coordinate the immune system's response to infectious agents such as viruses and bacteria.

CD4+ T cells recognize and bind to specific antigens presented by antigen-presenting cells, such as dendritic cells or macrophages. Once activated, they can differentiate into various subsets of effector cells, including Th1, Th2, Th17, and Treg cells, each with distinct functions in the immune response.

CD4+ T cells are particularly important in the immune response to HIV (human immunodeficiency virus), which targets and destroys these cells, leading to a weakened immune system and increased susceptibility to opportunistic infections. The number of CD4+ T cells is often used as a marker of disease progression in HIV infection, with lower counts indicating more advanced disease.

Long-term potentiation (LTP) is a persistent strengthening of synapses following high-frequency stimulation of their afferents. It is a cellular mechanism for learning and memory, where the efficacy of neurotransmission is increased at synapses in the hippocampus and other regions of the brain. LTP can last from hours to days or even weeks, depending on the type and strength of stimulation. It involves complex biochemical processes, including changes in the number and sensitivity of receptors for neurotransmitters, as well as alterations in the structure and function of synaptic connections between neurons. LTP is widely studied as a model for understanding the molecular basis of learning and memory.

Aging is a complex, progressive and inevitable process of bodily changes over time, characterized by the accumulation of cellular damage and degenerative changes that eventually lead to increased vulnerability to disease and death. It involves various biological, genetic, environmental, and lifestyle factors that contribute to the decline in physical and mental functions. The medical field studies aging through the discipline of gerontology, which aims to understand the underlying mechanisms of aging and develop interventions to promote healthy aging and extend the human healthspan.

Visual pattern recognition is the ability to identify and interpret patterns in visual information. In a medical context, it often refers to the process by which healthcare professionals recognize and diagnose medical conditions based on visible signs or symptoms. This can involve recognizing the characteristic appearance of a rash, wound, or other physical feature associated with a particular disease or condition. It may also involve recognizing patterns in medical images such as X-rays, CT scans, or MRIs.

In the field of radiology, for example, visual pattern recognition is a critical skill. Radiologists are trained to recognize the typical appearances of various diseases and conditions in medical images. This allows them to make accurate diagnoses based on the patterns they see. Similarly, dermatologists use visual pattern recognition to identify skin abnormalities and diseases based on the appearance of rashes, lesions, or other skin changes.

Overall, visual pattern recognition is an essential skill in many areas of medicine, allowing healthcare professionals to quickly and accurately diagnose medical conditions based on visible signs and symptoms.

Paired-associate learning is a form of implicit or non-declarative memory task that involves learning and remembering the association between two unrelated items, such as a word and an object, or a taste and a sound. In this type of learning, the individual learns to respond appropriately when presented with one member of the pair, due to its association with the other member. This process is often used in various fields including cognitive psychology, neuroscience, and education to study memory, learning, and brain function.

Exploratory behavior refers to the actions taken by an individual to investigate and gather information about their environment. This type of behavior is often driven by curiosity and a desire to understand new or unfamiliar situations, objects, or concepts. In a medical context, exploratory behavior may refer to a patient's willingness to learn more about their health condition, try new treatments, or engage in self-care activities. It can also refer to the behaviors exhibited by young children as they explore their world and develop their cognitive and motor skills. Exploratory behavior is an important aspect of learning and development, and it can have a positive impact on overall health and well-being.

"Mushroom bodies" is a term that is primarily used in the field of insect neuroanatomy, rather than human or mammalian medicine. They are a pair of prominent structures in the insect brain, located in the olfactory processing center and involved in sensory integration, learning, and memory.

These structures have a distinctive morphology, resembling a mushroom with a large cap-like structure (the calyx) sitting atop a stalk (the peduncle). The calyx receives input from various sensory neurons, while the peduncle and its downstream processes are involved in information processing and output.

While not directly relevant to human medicine, understanding the organization and function of insect nervous systems can provide valuable insights into the evolution of neural circuits and behaviors across species.

An autobiography is a type of literature that describes the personal life experiences of an individual, written by that individual. It typically includes details about their upbringing, education, career, relationships, and other significant events in their life. The author may also reflect on their thoughts, feelings, and motivations during these experiences, providing insight into their personality and character.

Autobiographies can serve various purposes, such as sharing one's story with others, leaving a legacy for future generations, or exploring one's personal growth and development. They can be written in different styles, from straightforward and factual to introspective and reflective.

It is important to note that autobiographies are not always entirely accurate, as memory can be selective or distorted. Additionally, some individuals may choose to embellish or exaggerate certain aspects of their lives for dramatic effect or to protect the privacy of others. Nonetheless, autobiographies remain a valuable source of information about an individual's life and experiences.

Visual perception refers to the ability to interpret and organize information that comes from our eyes to recognize and understand what we are seeing. It involves several cognitive processes such as pattern recognition, size estimation, movement detection, and depth perception. Visual perception allows us to identify objects, navigate through space, and interact with our environment. Deficits in visual perception can lead to learning difficulties and disabilities.

T-lymphocyte subsets refer to distinct populations of T-cells, which are a type of white blood cell that plays a central role in cell-mediated immunity. The two main types of T-lymphocytes are CD4+ and CD8+ cells, which are defined by the presence or absence of specific proteins called cluster differentiation (CD) molecules on their surface.

CD4+ T-cells, also known as helper T-cells, play a crucial role in activating other immune cells, such as B-lymphocytes and macrophages, to mount an immune response against pathogens. They also produce cytokines that help regulate the immune response.

CD8+ T-cells, also known as cytotoxic T-cells, directly kill infected cells or tumor cells by releasing toxic substances such as perforins and granzymes.

The balance between these two subsets of T-cells is critical for maintaining immune homeostasis and mounting effective immune responses against pathogens while avoiding excessive inflammation and autoimmunity. Therefore, the measurement of T-lymphocyte subsets is essential in diagnosing and monitoring various immunological disorders, including HIV infection, cancer, and autoimmune diseases.

Executive function is a term used to describe a set of cognitive processes that are necessary for the control and regulation of thought and behavior. These functions include:

1. Working memory: The ability to hold and manipulate information in mind over short periods of time.
2. Cognitive flexibility: The ability to switch between tasks or mental sets, and to adapt to new rules and situations.
3. Inhibitory control: The ability to inhibit or delay automatic responses, and to resist impulses and distractions.
4. Planning and organization: The ability to plan and organize actions, and to manage time and resources effectively.
5. Problem-solving: The ability to analyze problems, generate solutions, and evaluate the outcomes of actions.
6. Decision-making: The ability to weigh risks and benefits, and to make informed choices based on available information.
7. Emotional regulation: The ability to manage and regulate emotions, and to respond appropriately to social cues and situations.

Executive functions are primarily controlled by the frontal lobes of the brain, and they play a critical role in goal-directed behavior, problem-solving, decision-making, and self-regulation. Deficits in executive function can have significant impacts on daily life, including difficulties with academic performance, work productivity, social relationships, and mental health.

Lymphocyte activation is the process by which B-cells and T-cells (types of lymphocytes) become activated to perform effector functions in an immune response. This process involves the recognition of specific antigens presented on the surface of antigen-presenting cells, such as dendritic cells or macrophages.

The activation of B-cells leads to their differentiation into plasma cells that produce antibodies, while the activation of T-cells results in the production of cytotoxic T-cells (CD8+ T-cells) that can directly kill infected cells or helper T-cells (CD4+ T-cells) that assist other immune cells.

Lymphocyte activation involves a series of intracellular signaling events, including the binding of co-stimulatory molecules and the release of cytokines, which ultimately result in the expression of genes involved in cell proliferation, differentiation, and effector functions. The activation process is tightly regulated to prevent excessive or inappropriate immune responses that can lead to autoimmunity or chronic inflammation.

Transgenic mice are genetically modified rodents that have incorporated foreign DNA (exogenous DNA) into their own genome. This is typically done through the use of recombinant DNA technology, where a specific gene or genetic sequence of interest is isolated and then introduced into the mouse embryo. The resulting transgenic mice can then express the protein encoded by the foreign gene, allowing researchers to study its function in a living organism.

The process of creating transgenic mice usually involves microinjecting the exogenous DNA into the pronucleus of a fertilized egg, which is then implanted into a surrogate mother. The offspring that result from this procedure are screened for the presence of the foreign DNA, and those that carry the desired genetic modification are used to establish a transgenic mouse line.

Transgenic mice have been widely used in biomedical research to model human diseases, study gene function, and test new therapies. They provide a valuable tool for understanding complex biological processes and developing new treatments for a variety of medical conditions.

"Long-Evans" is a strain of laboratory rats commonly used in scientific research. They are named after their developers, the scientists Long and Evans. This strain is albino, with a brownish-black hood over their eyes and ears, and they have an agouti (salt-and-pepper) color on their backs. They are often used as a model organism due to their size, ease of handling, and genetic similarity to humans. However, I couldn't find any specific medical definition related to "Long-Evans rats" as they are not a medical condition or disease.

A learning disorder is a neurodevelopmental disorder that affects an individual's ability to acquire, process, and use information in one or more academic areas despite normal intelligence and adequate instruction. It can manifest as difficulties with reading (dyslexia), writing (dysgraphia), mathematics (dyscalculia), or other academic skills. Learning disorders are not the result of low intelligence, lack of motivation, or environmental factors alone, but rather reflect a significant discrepancy between an individual's cognitive abilities and their academic achievement. They can significantly impact a person's ability to perform in school, at work, and in daily life, making it important to diagnose and manage these disorders effectively.

Emotions are complex psychological states that involve three distinct components: a subjective experience, a physiological response, and a behavioral or expressive response. Emotions can be short-lived, such as a flash of anger, or more long-lasting, such as enduring sadness. They can also vary in intensity, from mild irritation to intense joy or fear.

Emotions are often distinguished from other psychological states, such as moods and temperament, which may be less specific and more enduring. Emotions are typically thought to have a clear cause or object, such as feeling happy when you receive good news or feeling anxious before a job interview.

There are many different emotions that people can experience, including happiness, sadness, anger, fear, surprise, disgust, and shame. These emotions are often thought to serve important adaptive functions, helping individuals respond to challenges and opportunities in their environment.

In medical contexts, emotions may be relevant to the diagnosis and treatment of various mental health conditions, such as depression, anxiety disorders, and bipolar disorder. Abnormalities in emotional processing and regulation have been implicated in many psychiatric illnesses, and therapies that target these processes may be effective in treating these conditions.

Neurons, also known as nerve cells or neurocytes, are specialized cells that constitute the basic unit of the nervous system. They are responsible for receiving, processing, and transmitting information and signals within the body. Neurons have three main parts: the dendrites, the cell body (soma), and the axon. The dendrites receive signals from other neurons or sensory receptors, while the axon transmits these signals to other neurons, muscles, or glands. The junction between two neurons is called a synapse, where neurotransmitters are released to transmit the signal across the gap (synaptic cleft) to the next neuron. Neurons vary in size, shape, and structure depending on their function and location within the nervous system.

Anterograde amnesia is a specific type of memory loss where a person has difficulty forming new memories or learning and retaining new information after the onset of the amnesia. It is often caused by damage to certain parts of the brain, such as the hippocampus and surrounding structures, which play a crucial role in the formation of new memories.

In anterograde amnesia, people may have trouble remembering events that occurred after the onset of their memory impairment, while their ability to recall remote memories or those that were formed before the onset of the amnesia is typically preserved. The severity of anterograde amnesia can vary widely, from mild difficulty with learning new information to a complete inability to form any new memories.

Anterograde amnesia can be caused by various factors, including brain injury, infection, stroke, alcohol or drug abuse, seizures, and certain medical conditions such as Wernicke-Korsakoff syndrome, which is often associated with chronic alcoholism. Treatment for anterograde amnesia depends on the underlying cause and may involve medication, rehabilitation, or other interventions to help improve memory function.

Scopolamine hydrobromide is a synthetic anticholinergic drug, which means it blocks the action of acetylcholine, a neurotransmitter in the nervous system. It is primarily used for its anti-motion sickness and anti-nausea effects. It can also be used to help with symptoms of Parkinson's disease, such as muscle stiffness and tremors.

In medical settings, scopolamine hydrobromide may be administered as a transdermal patch, which is placed behind the ear to allow for slow release into the body over several days. It can also be given as an injection or taken orally in the form of tablets or liquid solutions.

It's important to note that scopolamine hydrobromide can have various side effects, including dry mouth, blurred vision, dizziness, and drowsiness. It may also cause confusion, especially in older adults, and should be used with caution in patients with glaucoma, enlarged prostate, or certain heart conditions.

Alzheimer's disease is a progressive disorder that causes brain cells to waste away (degenerate) and die. It's the most common cause of dementia — a continuous decline in thinking, behavioral and social skills that disrupts a person's ability to function independently.

The early signs of the disease include forgetting recent events or conversations. As the disease progresses, a person with Alzheimer's disease will develop severe memory impairment and lose the ability to carry out everyday tasks.

Currently, there's no cure for Alzheimer's disease. However, treatments can temporarily slow the worsening of dementia symptoms and improve quality of life.

"Extinction, Psychological" refers to the process by which a conditioned response or behavior becomes weakened and eventually disappears when the behavior is no longer reinforced or rewarded. It is a fundamental concept in learning theory and conditioning.

In classical conditioning, extinction occurs when the conditioned stimulus (CS) is repeatedly presented without the unconditioned stimulus (US), leading to the gradual weakening and eventual disappearance of the conditioned response (CR). For example, if a person learns to associate a tone (CS) with a puff of air to the eye (US), causing blinking (CR), but then the tone is presented several times without the puff of air, the blinking response will become weaker and eventually disappear.

In operant conditioning, extinction occurs when a reinforcer is no longer provided following a behavior, leading to the gradual weakening and eventual disappearance of that behavior. For example, if a child receives candy every time they clean their room (reinforcement), but then the candy is withheld, the child may eventually stop cleaning their room (extinction).

It's important to note that extinction can be a slow process and may require multiple trials or repetitions. Additionally, behaviors that have been extinguished can sometimes reappear in certain circumstances, a phenomenon known as spontaneous recovery.

Electroshock, also known as electroconvulsive therapy (ECT), is a medical procedure in which electric currents are passed through the brain to treat certain mental health conditions. It is primarily used to treat severe forms of depression that have not responded to other treatments, and it may also be used to treat bipolar disorder and schizophrenia.

During an ECT procedure, electrodes are placed on the patient's head, and a carefully controlled electric current is passed through the brain, intentionally triggering a seizure. The patient is under general anesthesia and given muscle relaxants to prevent physical injury from the seizure.

ECT is typically administered in a series of treatments, usually two or three times a week for several weeks. While the exact mechanism of action is not fully understood, ECT is thought to affect brain chemistry and help regulate mood and other symptoms. It is generally considered a safe and effective treatment option for certain mental health conditions when other treatments have failed. However, it can have side effects, including short-term memory loss and confusion, and it may not be appropriate for everyone.

Neural pathways, also known as nerve tracts or fasciculi, refer to the highly organized and specialized routes through which nerve impulses travel within the nervous system. These pathways are formed by groups of neurons (nerve cells) that are connected in a series, creating a continuous communication network for electrical signals to transmit information between different regions of the brain, spinal cord, and peripheral nerves.

Neural pathways can be classified into two main types: sensory (afferent) and motor (efferent). Sensory neural pathways carry sensory information from various receptors in the body (such as those for touch, temperature, pain, and vision) to the brain for processing. Motor neural pathways, on the other hand, transmit signals from the brain to the muscles and glands, controlling movements and other effector functions.

The formation of these neural pathways is crucial for normal nervous system function, as it enables efficient communication between different parts of the body and allows for complex behaviors, cognitive processes, and adaptive responses to internal and external stimuli.

Functional laterality, in a medical context, refers to the preferential use or performance of one side of the body over the other for specific functions. This is often demonstrated in hand dominance, where an individual may be right-handed or left-handed, meaning they primarily use their right or left hand for tasks such as writing, eating, or throwing.

However, functional laterality can also apply to other bodily functions and structures, including the eyes (ocular dominance), ears (auditory dominance), or legs. It's important to note that functional laterality is not a strict binary concept; some individuals may exhibit mixed dominance or no strong preference for one side over the other.

In clinical settings, assessing functional laterality can be useful in diagnosing and treating various neurological conditions, such as stroke or traumatic brain injury, where understanding any resulting lateralized impairments can inform rehabilitation strategies.

CD27 is a protein that is found on the surface of certain immune cells, including T cells and B cells. It is a type of molecule known as a cell-surface antigen, which can be recognized by other immune cells and used to target those cells for activation or destruction. CD27 plays a role in the regulation of the immune response, particularly in the activation and differentiation of T cells.

CD27 is also a member of the tumor necrosis factor receptor (TNFR) superfamily, which means that it has a specific structure and function that allows it to interact with other molecules called ligands. The interaction between CD27 and its ligand, CD70, helps to activate T cells and promote their survival and proliferation.

In addition to its role in the immune response, CD27 has also been studied as a potential target for cancer immunotherapy. Because CD27 is expressed on certain types of tumor cells, it may be possible to use therapies that target CD27 to stimulate an immune response against the tumor and help to destroy it. However, more research is needed to determine the safety and effectiveness of these approaches.

A nerve net, also known as a neural net or neuronal network, is not a medical term per se, but rather a concept in neuroscience and artificial intelligence (AI). It refers to a complex network of interconnected neurons that process and transmit information. In the context of the human body, the nervous system can be thought of as a type of nerve net, with the brain and spinal cord serving as the central processing unit and peripheral nerves carrying signals to and from various parts of the body.

In the field of AI, artificial neural networks are computational models inspired by the structure and function of biological nerve nets. These models consist of interconnected nodes or "neurons" that process information and learn patterns through a process of training and adaptation. They have been used in a variety of applications, including image recognition, natural language processing, and machine learning.

In medical terms, "association" is a relationship between two or more variables, conditions, or factors in which they consistently occur together more often than would be expected by chance. This does not necessarily mean that one causes the other, but simply that they are connected in some way. The association can be positive (meaning that as one variable increases, so does the other) or negative (meaning that as one variable increases, the other decreases).

For example, there is a well-known association between smoking and lung cancer, meaning that people who smoke are more likely to develop lung cancer than those who do not. However, this does not mean that smoking causes lung cancer, only that the two are linked in some way. Further research is needed to establish causality.

In medical terms, the sense of smell is referred to as olfaction. It is the ability to detect and identify different types of chemicals in the air through the use of the olfactory system. The olfactory system includes the nose, nasal passages, and the olfactory bulbs located in the brain.

When a person inhales air containing volatile substances, these substances bind to specialized receptor cells in the nasal passage called olfactory receptors. These receptors then transmit signals to the olfactory bulbs, which process the information and send it to the brain's limbic system, including the hippocampus and amygdala, as well as to the cortex. The brain interprets these signals and identifies the various scents or smells.

Impairment of the sense of smell can occur due to various reasons such as upper respiratory infections, sinusitis, nasal polyps, head trauma, or neurodegenerative disorders like Parkinson's disease and Alzheimer's disease. Loss of smell can significantly impact a person's quality of life, including their ability to taste food, detect dangers such as smoke or gas leaks, and experience emotions associated with certain smells.

Discrimination learning is a type of learning in which an individual learns to distinguish between two or more stimuli and respond differently to each. It involves the ability to recognize the differences between similar stimuli and to respond appropriately based on the specific characteristics of each stimulus. This type of learning is important for many aspects of cognition, including perception, language, and problem-solving.

In discrimination learning, an individual may be presented with two or more stimuli and reinforced for responding differently to each. For example, a person might be trained to press a button in response to the color red and to do nothing in response to the color green. Through this process of differential reinforcement, the individual learns to discriminate between the two colors and to respond appropriately to each.

Discrimination learning is often studied in animals as well as humans, and it is thought to involve a range of cognitive processes, including attention, memory, and perception. It is an important aspect of many forms of learning and plays a role in a wide variety of behaviors.

'Task Performance and Analysis' is not a commonly used medical term, but it can be found in the field of rehabilitation medicine and ergonomics. It refers to the process of evaluating and understanding how a specific task is performed, in order to identify any physical or cognitive demands placed on an individual during the performance of that task. This information can then be used to inform the design of interventions, such as workplace modifications or rehabilitation programs, aimed at improving task performance or reducing the risk of injury.

In a medical context, task performance and analysis may be used in the assessment and treatment of individuals with disabilities or injuries, to help them return to work or other activities of daily living. The analysis involves breaking down the task into its component parts, observing and measuring the physical and cognitive demands of each part, and evaluating the individual's ability to perform those demands. Based on this analysis, recommendations may be made for modifications to the task or the environment, training or education, or assistive devices that can help the individual perform the task more safely and efficiently.

Overall, task performance and analysis is a valuable tool in promoting safe and effective task performance, reducing the risk of injury, and improving functional outcomes for individuals with disabilities or injuries.

In the context of medicine, "odors" refer to smells or scents that are produced by certain medical conditions, substances, or bodily functions. These odors can sometimes provide clues about underlying health issues. For example, sweet-smelling urine could indicate diabetes, while foul-smelling breath might suggest a dental problem or gastrointestinal issue. However, it's important to note that while odors can sometimes be indicative of certain medical conditions, they are not always reliable diagnostic tools and should be considered in conjunction with other symptoms and medical tests.

The parietal lobe is a region of the brain that is located in the posterior part of the cerebral cortex, covering the upper and rear portions of the brain. It is involved in processing sensory information from the body, such as touch, temperature, and pain, as well as spatial awareness and perception, visual-spatial cognition, and the integration of different senses.

The parietal lobe can be divided into several functional areas, including the primary somatosensory cortex (which receives tactile information from the body), the secondary somatosensory cortex (which processes more complex tactile information), and the posterior parietal cortex (which is involved in spatial attention, perception, and motor planning).

Damage to the parietal lobe can result in various neurological symptoms, such as neglect of one side of the body, difficulty with spatial orientation, problems with hand-eye coordination, and impaired mathematical and language abilities.

The frontal lobe is the largest lobes of the human brain, located at the front part of each cerebral hemisphere and situated in front of the parietal and temporal lobes. It plays a crucial role in higher cognitive functions such as decision making, problem solving, planning, parts of social behavior, emotional expressions, physical reactions, and motor function. The frontal lobe is also responsible for what's known as "executive functions," which include the ability to focus attention, understand rules, switch focus, plan actions, and inhibit inappropriate behaviors. It is divided into five areas, each with its own specific functions: the primary motor cortex, premotor cortex, Broca's area, prefrontal cortex, and orbitofrontal cortex. Damage to the frontal lobe can result in a wide range of impairments, depending on the location and extent of the injury.

Computer-assisted image processing is a medical term that refers to the use of computer systems and specialized software to improve, analyze, and interpret medical images obtained through various imaging techniques such as X-ray, CT (computed tomography), MRI (magnetic resonance imaging), ultrasound, and others.

The process typically involves several steps, including image acquisition, enhancement, segmentation, restoration, and analysis. Image processing algorithms can be used to enhance the quality of medical images by adjusting contrast, brightness, and sharpness, as well as removing noise and artifacts that may interfere with accurate diagnosis. Segmentation techniques can be used to isolate specific regions or structures of interest within an image, allowing for more detailed analysis.

Computer-assisted image processing has numerous applications in medical imaging, including detection and characterization of lesions, tumors, and other abnormalities; assessment of organ function and morphology; and guidance of interventional procedures such as biopsies and surgeries. By automating and standardizing image analysis tasks, computer-assisted image processing can help to improve diagnostic accuracy, efficiency, and consistency, while reducing the potential for human error.

I'm sorry for any confusion, but "semantics" is not a term that has a specific medical definition. Semantics is actually a branch of linguistics that deals with the study of meaning, reference, and the interpretation of signs and symbols, either individually or in combination. It is used in various fields including computer science, anthropology, psychology, and philosophy.

However, if you have any medical terms or concepts that you would like me to explain, I'd be happy to help!

A "knockout" mouse is a genetically engineered mouse in which one or more genes have been deleted or "knocked out" using molecular biology techniques. This allows researchers to study the function of specific genes and their role in various biological processes, as well as potential associations with human diseases. The mice are generated by introducing targeted DNA modifications into embryonic stem cells, which are then used to create a live animal. Knockout mice have been widely used in biomedical research to investigate gene function, disease mechanisms, and potential therapeutic targets.

Anisomycin is an antibiotic derived from the bacterium Streptomyces griseolus. It is a potent inhibitor of protein synthesis and has been found to have antitumor, antiviral, and immunosuppressive properties. In medicine, it has been used experimentally in the treatment of some types of cancer, but its use is limited due to its significant side effects, including neurotoxicity.

In a medical or scientific context, 'anisomycin' refers specifically to this antibiotic compound and not to any general concept related to aniso- (meaning "unequal" or "asymmetrical") or -mycin (suffix indicating a bacterial antibiotic).

In the context of medical and clinical psychology, particularly in the field of applied behavior analysis (ABA), "verbal behavior" is a term used to describe the various functions or purposes of spoken language. It was first introduced by the psychologist B.F. Skinner in his 1957 book "Verbal Behavior."

Skinner proposed that verbal behavior could be classified into several categories based on its function, including:

1. Mand: A verbal operant in which a person requests or demands something from another person. For example, saying "I would like a glass of water" is a mand.
2. Tact: A verbal operant in which a person describes or labels something in their environment. For example, saying "That's a red apple" is a tact.
3. Echoic: A verbal operant in which a person repeats or imitates what they have heard. For example, saying "Hello" after someone says hello to you is an echoic.
4. Intraverbal: A verbal operant in which a person responds to another person's verbal behavior with their own verbal behavior, without simply repeating or imitating what they have heard. For example, answering a question like "What's the capital of France?" is an intraverbal.
5. Textual: A verbal operant in which a person reads or writes text. For example, reading a book or writing a letter are textual.

Understanding the function of verbal behavior can be helpful in assessing and treating communication disorders, such as those seen in autism spectrum disorder (ASD). By identifying the specific functions of a child's verbal behavior, therapists can develop targeted interventions to help them communicate more effectively.

The cerebral cortex is the outermost layer of the brain, characterized by its intricate folded structure and wrinkled appearance. It is a region of great importance as it plays a key role in higher cognitive functions such as perception, consciousness, thought, memory, language, and attention. The cerebral cortex is divided into two hemispheres, each containing four lobes: the frontal, parietal, temporal, and occipital lobes. These areas are responsible for different functions, with some regions specializing in sensory processing while others are involved in motor control or associative functions. The cerebral cortex is composed of gray matter, which contains neuronal cell bodies, and is covered by a layer of white matter that consists mainly of myelinated nerve fibers.

Neurological models are simplified representations or simulations of various aspects of the nervous system, including its structure, function, and processes. These models can be theoretical, computational, or physical and are used to understand, explain, and predict neurological phenomena. They may focus on specific neurological diseases, disorders, or functions, such as memory, learning, or movement. The goal of these models is to provide insights into the complex workings of the nervous system that cannot be easily observed or understood through direct examination alone.

The Wechsler Scales are a series of intelligence and neuropsychological tests used to assess various aspects of cognitive functioning in individuals across the lifespan. The scales include:

1. Wechsler Preschool and Primary Scale of Intelligence (WPPSI): Designed for children aged 2 years 6 months to 7 years 3 months, it measures verbal (e.g., vocabulary, comprehension) and performance (e.g., visual-motor integration, spatial reasoning) abilities.
2. Wechsler Intelligence Scale for Children (WISC): Developed for children aged 6 to 16 years, it evaluates verbal comprehension, perceptual reasoning, working memory, and processing speed.
3. Wechsler Adult Intelligence Scale (WAIS): Created for adults aged 16 to 90 years, it assesses similar domains as the WISC but with more complex tasks.
4. Wechsler Memory Scale (WMS): Designed to measure various aspects of memory functioning in individuals aged 16 to 89 years, including visual and auditory immediate and delayed recall, working memory, and attention.
5. Wechsler Abbreviated Scale of Intelligence (WASI): A brief version of the WAIS used for quicker intelligence screening in individuals aged 6 to 89 years.

These scales are widely used in clinical, educational, and research settings to identify strengths and weaknesses in cognitive abilities, diagnose learning disabilities and other neurodevelopmental disorders, monitor treatment progress, and provide recommendations for interventions and accommodations.

Serial learning is a form of learning in which new information or skills are acquired and organized in a sequential manner, with each piece of information building on the previous one. In other words, it involves learning items or concepts one at a time, in a specific order, rather than all at once. This type of learning is often used in situations where the material to be learned has a clear sequence, such as learning the alphabet, numbers, or days of the week.

In a medical context, serial learning may be used to teach complex medical procedures or concepts that have multiple steps or components. For example, a medical student may learn how to perform a physical examination by first learning how to take a patient's vital signs, then moving on to inspecting various parts of the body in a specific order. Through repeated practice and reinforcement, the student gradually builds up a sequence of skills and knowledge that becomes integrated into their long-term memory.

It is worth noting that some individuals may find serial learning more challenging than other forms of learning, particularly if they have difficulty with sequential processing or working memory limitations. Therefore, individualized instruction and accommodations may be necessary to support learners who struggle with serial learning tasks.

B-lymphocytes, also known as B-cells, are a type of white blood cell that plays a key role in the immune system's response to infection. They are responsible for producing antibodies, which are proteins that help to neutralize or destroy pathogens such as bacteria and viruses.

When a B-lymphocyte encounters a pathogen, it becomes activated and begins to divide and differentiate into plasma cells, which produce and secrete large amounts of antibodies specific to the antigens on the surface of the pathogen. These antibodies bind to the pathogen, marking it for destruction by other immune cells such as neutrophils and macrophages.

B-lymphocytes also have a role in presenting antigens to T-lymphocytes, another type of white blood cell involved in the immune response. This helps to stimulate the activation and proliferation of T-lymphocytes, which can then go on to destroy infected cells or help to coordinate the overall immune response.

Overall, B-lymphocytes are an essential part of the adaptive immune system, providing long-lasting immunity to previously encountered pathogens and helping to protect against future infections.

The entorhinal cortex is a region in the brain that is located in the medial temporal lobe and is part of the limbic system. It plays a crucial role in memory, navigation, and the processing of sensory information. The entorhinal cortex is closely connected to the hippocampus, which is another important structure for memory and spatial cognition.

The entorhinal cortex can be divided into several subregions, including the lateral, medial, and posterior sections. These subregions have distinct connectivity patterns and may contribute differently to various cognitive functions. One of the most well-known features of the entorhinal cortex is the presence of "grid cells," which are neurons that fire in response to specific spatial locations and help to form a cognitive map of the environment.

Damage to the entorhinal cortex has been linked to several neurological and psychiatric conditions, including Alzheimer's disease, epilepsy, and schizophrenia.

Electroencephalography (EEG) is a medical procedure that records electrical activity in the brain. It uses small, metal discs called electrodes, which are attached to the scalp with paste or a specialized cap. These electrodes detect tiny electrical charges that result from the activity of brain cells, and the EEG machine then amplifies and records these signals.

EEG is used to diagnose various conditions related to the brain, such as seizures, sleep disorders, head injuries, infections, and degenerative diseases like Alzheimer's or Parkinson's. It can also be used during surgery to monitor brain activity and ensure that surgical procedures do not interfere with vital functions.

EEG is a safe and non-invasive procedure that typically takes about 30 minutes to an hour to complete, although longer recordings may be necessary in some cases. Patients are usually asked to relax and remain still during the test, as movement can affect the quality of the recording.

CD45 is a protein that is found on the surface of many types of white blood cells, including T-cells, B-cells, and natural killer (NK) cells. It is also known as leukocyte common antigen because it is present on almost all leukocytes. CD45 is a tyrosine phosphatase that plays a role in regulating the activity of various proteins involved in cell signaling pathways.

As an antigen, CD45 is used as a marker to identify and distinguish different types of white blood cells. It has several isoforms that are generated by alternative splicing of its mRNA, resulting in different molecular weights. The size of the CD45 isoform can be used to distinguish between different subsets of T-cells and B-cells.

CD45 is an important molecule in the immune system, and abnormalities in its expression or function have been implicated in various diseases, including autoimmune disorders and cancer.

A synapse is a structure in the nervous system that allows for the transmission of signals from one neuron (nerve cell) to another. It is the point where the axon terminal of one neuron meets the dendrite or cell body of another, and it is here that neurotransmitters are released and received. The synapse includes both the presynaptic and postsynaptic elements, as well as the cleft between them.

At the presynaptic side, an action potential travels down the axon and triggers the release of neurotransmitters into the synaptic cleft through exocytosis. These neurotransmitters then bind to receptors on the postsynaptic side, which can either excite or inhibit the receiving neuron. The strength of the signal between two neurons is determined by the number and efficiency of these synapses.

Synapses play a crucial role in the functioning of the nervous system, allowing for the integration and processing of information from various sources. They are also dynamic structures that can undergo changes in response to experience or injury, which has important implications for learning, memory, and recovery from neurological disorders.

Immunophenotyping is a medical laboratory technique used to identify and classify cells, usually in the context of hematologic (blood) disorders and malignancies (cancers), based on their surface or intracellular expression of various proteins and antigens. This technique utilizes specific antibodies tagged with fluorochromes, which bind to the target antigens on the cell surface or within the cells. The labeled cells are then analyzed using flow cytometry, allowing for the detection and quantification of multiple antigenic markers simultaneously.

Immunophenotyping helps in understanding the distribution of different cell types, their subsets, and activation status, which can be crucial in diagnosing various hematological disorders, immunodeficiencies, and distinguishing between different types of leukemias, lymphomas, and other malignancies. Additionally, it can also be used to monitor the progression of diseases, evaluate the effectiveness of treatments, and detect minimal residual disease (MRD) during follow-up care.

I'm sorry for any confusion, but "imagnation" is not a term typically used in medical definitions. Imagination generally refers to the ability to form mental images or concepts of things that are not present or have never been experienced. It involves the cognitive process of creating new ideas, scenarios, or concepts from existing knowledge and experiences.

However, if you meant to ask for a medical term related to imagination, one possibility could be "**productive thinking**" or **"generative cognitive processes"**. These terms are used in neuropsychology and cognitive science to describe the mental activities involved in creating new ideas, problem-solving, and generating novel responses.

If you had something specific in mind or if there's a different context you'd like me to consider, please provide more information, and I will do my best to help.

Sprague-Dawley rats are a strain of albino laboratory rats that are widely used in scientific research. They were first developed by researchers H.H. Sprague and R.C. Dawley in the early 20th century, and have since become one of the most commonly used rat strains in biomedical research due to their relatively large size, ease of handling, and consistent genetic background.

Sprague-Dawley rats are outbred, which means that they are genetically diverse and do not suffer from the same limitations as inbred strains, which can have reduced fertility and increased susceptibility to certain diseases. They are also characterized by their docile nature and low levels of aggression, making them easier to handle and study than some other rat strains.

These rats are used in a wide variety of research areas, including toxicology, pharmacology, nutrition, cancer, and behavioral studies. Because they are genetically diverse, Sprague-Dawley rats can be used to model a range of human diseases and conditions, making them an important tool in the development of new drugs and therapies.

Nootropic agents, also known as cognition enhancers or smart drugs, are substances that are believed to improve cognitive functions such as memory, motivation, creativity, and executive functions. The term "nootropic" is derived from the Greek words "nous," meaning mind, and "tropos," meaning a turn or bend.

Nootropics can be divided into several categories, including dietary supplements, prescription medications, and illicit substances. Some examples of nootropics include:

* Piracetam and other racetams
* Caffeine and other stimulants
* Nicotine and other cholinergic compounds
* Modafinil and other wakefulness-promoting agents
* Certain antidepressants, such as fluoxetine and bupropion
* Illicit substances, such as methylphenidate (Ritalin) and amphetamines (Adderall), which are sometimes used off-label for cognitive enhancement.

It is important to note that while some nootropic agents have been shown to have cognitive benefits in certain studies, their effectiveness and safety are not fully understood. Additionally, the long-term use of some nootropics can have potential risks and side effects. Therefore, it is recommended to consult with a healthcare professional before starting any new supplement or medication regimen for cognitive enhancement.

In the context of medical definitions, "judgment" generally refers to the ability to make decisions or form opinions regarding a patient's condition or treatment. It involves critical thinking, clinical reasoning, and knowledge of medical principles and practices. In some cases, it may also refer to a medical professional's assessment or evaluation of a patient's health status or response to treatment.

However, it is important to note that "judgment" is not a term with a specific medical definition, and its meaning can vary depending on the context in which it is used. In general, it refers to the ability to make sound decisions based on evidence, experience, and expertise.

The CA1 region, also known as the cornu ammonis 1 region, is a subfield located in the hippocampus, a complex brain structure that plays a crucial role in learning and memory. The hippocampus is divided into several subregions, including the CA fields (CA1, CA2, CA3, and CA4).

The CA1 region is situated in the hippocampal formation's hippocampus proper and is characterized by its distinct neuronal architecture. It contains densely packed pyramidal cells, which are the primary excitatory neurons in this area. These pyramidal cells receive input from various sources, including the entorhinal cortex, another crucial region for memory functions.

The CA1 region plays a significant role in spatial memory and contextual learning. It is particularly vulnerable to damage and degeneration in several neurological conditions, such as Alzheimer's disease, epilepsy, and ischemic injuries. The selective loss of CA1 pyramidal cells is one of the earliest signs of Alzheimer's disease, which contributes to memory impairments observed in this disorder.

Theta rhythm is a type of electrical brain activity that can be detected through an electroencephalogram (EEG), which measures the electrical impulses generated by the brain's neurons. Theta waves have a frequency range of 4-8 Hz and are typically observed in the EEG readings of children, as well as adults during states of drowsiness, light sleep, or deep meditation.

Theta rhythm is thought to be involved in several cognitive processes, including memory consolidation, spatial navigation, and emotional regulation. It has also been associated with various mental states, such as creativity, intuition, and heightened suggestibility. However, more research is needed to fully understand the functional significance of theta rhythm and its role in brain function.

B-lymphocytes, also known as B-cells, are a type of white blood cell that plays a central role in the humoral immune response. They are responsible for producing antibodies, which are proteins that help to neutralize or destroy pathogens such as viruses and bacteria.

B-lymphocyte subsets refer to distinct populations of B-cells that can be identified based on their surface receptors and functional characteristics. Some common B-lymphocyte subsets include:

1. Naive B-cells: These are mature B-cells that have not yet been exposed to an antigen. They express surface receptors called immunoglobulin M (IgM) and immunoglobulin D (IgD).
2. Memory B-cells: These are B-cells that have previously encountered an antigen and mounted an immune response. They express high levels of surface immunoglobulins and can quickly differentiate into antibody-secreting plasma cells upon re-exposure to the same antigen.
3. Plasma cells: These are fully differentiated B-cells that secrete large amounts of antibodies in response to an antigen. They lack surface immunoglobulins and do not undergo further division.
4. Regulatory B-cells: These are a subset of B-cells that modulate the immune response by producing anti-inflammatory cytokines and suppressing the activation of other immune cells.
5. B-1 cells: These are a population of B-cells that are primarily found in the peripheral blood and mucosal tissues. They produce natural antibodies that provide early protection against pathogens and help to maintain tissue homeostasis.

Understanding the different B-lymphocyte subsets and their functions is important for diagnosing and treating immune-related disorders, including autoimmune diseases, infections, and cancer.

Secondary immunization, also known as "anamnestic response" or "booster," refers to the enhanced immune response that occurs upon re-exposure to an antigen, having previously been immunized or infected with the same pathogen. This response is characterized by a more rapid and robust production of antibodies and memory cells compared to the primary immune response. The secondary immunization aims to maintain long-term immunity against infectious diseases and improve vaccine effectiveness. It usually involves administering additional doses of a vaccine or booster shots after the initial series of immunizations, which helps reinforce the immune system's ability to recognize and combat specific pathogens.

Lymphocytic choriomeningitis virus (LCMV) is an Old World arenavirus that primarily infects rodents, particularly the house mouse (Mus musculus). The virus is harbored in these mice without causing any apparent disease, but they can shed the virus in their urine, droppings, and saliva.

Humans can contract LCMV through close contact with infected rodents or their excreta, inhalation of aerosolized virus, or ingestion of contaminated food or water. In humans, LCMV infection can cause a mild to severe illness called lymphocytic choriomeningitis (LCM), which primarily affects the meninges (the membranes surrounding the brain and spinal cord) and, less frequently, the brain and spinal cord itself.

The incubation period for LCMV infection is typically 1-2 weeks, after which symptoms may appear. Initial symptoms include fever, malaise, headache, muscle aches, and nausea. In some cases, the illness may progress to involve the meninges (meningitis), resulting in neck stiffness, light sensitivity, and altered mental status. In rare instances, LCMV infection can lead to encephalitis (inflammation of the brain) or myelitis (inflammation of the spinal cord), causing more severe neurological symptoms such as seizures, paralysis, or long-term neurological damage.

Most individuals who contract LCMV recover completely within a few weeks to months; however, immunocompromised individuals are at risk for developing severe and potentially fatal complications from the infection. Pregnant women infected with LCMV may also face an increased risk of miscarriage or fetal abnormalities.

Prevention measures include avoiding contact with rodents, especially house mice, and their excreta, maintaining good hygiene, and using appropriate personal protective equipment when handling potentially contaminated materials. There is no specific treatment for LCMV infection; management typically involves supportive care to alleviate symptoms and address complications as they arise.

N-Methyl-D-Aspartate (NMDA) receptors are a type of ionotropic glutamate receptor, which are found in the membranes of excitatory neurons in the central nervous system. They play a crucial role in synaptic plasticity, learning, and memory processes. NMDA receptors are ligand-gated channels that are permeable to calcium ions (Ca2+) and other cations.

NMDA receptors are composed of four subunits, which can be a combination of NR1, NR2A-D, and NR3A-B subunits. The binding of the neurotransmitter glutamate to the NR2 subunit and glycine to the NR1 subunit leads to the opening of the ion channel and the influx of Ca2+ ions.

NMDA receptors have a unique property in that they require both agonist binding and membrane depolarization for full activation, making them sensitive to changes in the electrical activity of the neuron. This property allows NMDA receptors to act as coincidence detectors, playing a critical role in synaptic plasticity and learning.

Abnormal functioning of NMDA receptors has been implicated in various neurological disorders, including Alzheimer's disease, Parkinson's disease, epilepsy, and chronic pain. Therefore, NMDA receptors are a common target for drug development in the treatment of these conditions.

"Macaca mulatta" is the scientific name for the Rhesus macaque, a species of monkey that is native to South, Central, and Southeast Asia. They are often used in biomedical research due to their genetic similarity to humans.

Psychological models are theoretical frameworks used in psychology to explain and predict mental processes and behaviors. They are simplified representations of complex phenomena, consisting of interrelated concepts, assumptions, and hypotheses that describe how various factors interact to produce specific outcomes. These models can be quantitative (e.g., mathematical equations) or qualitative (e.g., conceptual diagrams) in nature and may draw upon empirical data, theoretical insights, or both.

Psychological models serve several purposes:

1. They provide a systematic and organized way to understand and describe psychological phenomena.
2. They generate hypotheses and predictions that can be tested through empirical research.
3. They integrate findings from different studies and help synthesize knowledge across various domains of psychology.
4. They inform the development of interventions and treatments for mental health disorders.

Examples of psychological models include:

1. The Five Factor Model (FFM) of personality, which posits that individual differences in personality can be described along five broad dimensions: Openness, Conscientiousness, Extraversion, Agreeableness, and Neuroticism.
2. The Cognitive-Behavioral Therapy (CBT) model, which suggests that maladaptive thoughts, feelings, and behaviors are interconnected and can be changed through targeted interventions.
3. The Dual Process Theory of Attitudes, which proposes that attitudes are formed and influenced by two distinct processes: a rapid, intuitive process (heuristic) and a slower, deliberative process (systematic).
4. The Social Cognitive Theory, which emphasizes the role of observational learning, self-efficacy, and outcome expectations in shaping behavior.
5. The Attachment Theory, which describes the dynamics of long-term relationships between humans, particularly the parent-child relationship.

It is important to note that psychological models are provisional and subject to revision or replacement as new evidence emerges. They should be considered as useful tools for understanding and explaining psychological phenomena rather than definitive truths.

Evoked potentials (EPs) are medical tests that measure the electrical activity in the brain or spinal cord in response to specific sensory stimuli, such as sight, sound, or touch. These tests are often used to help diagnose and monitor conditions that affect the nervous system, such as multiple sclerosis, brainstem tumors, and spinal cord injuries.

There are several types of EPs, including:

1. Visual Evoked Potentials (VEPs): These are used to assess the function of the visual pathway from the eyes to the back of the brain. A patient is typically asked to look at a patterned image or flashing light while electrodes placed on the scalp record the electrical responses.
2. Brainstem Auditory Evoked Potentials (BAEPs): These are used to evaluate the function of the auditory nerve and brainstem. Clicking sounds are presented to one or both ears, and electrodes placed on the scalp measure the response.
3. Somatosensory Evoked Potentials (SSEPs): These are used to assess the function of the peripheral nerves and spinal cord. Small electrical shocks are applied to a nerve at the wrist or ankle, and electrodes placed on the scalp record the response as it travels up the spinal cord to the brain.
4. Motor Evoked Potentials (MEPs): These are used to assess the function of the motor pathways in the brain and spinal cord. A magnetic or electrical stimulus is applied to the brain or spinal cord, and electrodes placed on a muscle measure the response as it travels down the motor pathway.

EPs can help identify abnormalities in the nervous system that may not be apparent through other diagnostic tests, such as imaging studies or clinical examinations. They are generally safe, non-invasive procedures with few risks or side effects.

Adoptive transfer is a medical procedure in which immune cells are transferred from a donor to a recipient with the aim of providing immunity or treating a disease, such as cancer. This technique is often used in the field of immunotherapy and involves isolating specific immune cells (like T-cells) from the donor, expanding their numbers in the laboratory, and then infusing them into the patient. The transferred cells are expected to recognize and attack the target cells, such as malignant or infected cells, leading to a therapeutic effect. This process requires careful matching of donor and recipient to minimize the risk of rejection and graft-versus-host disease.

Flow cytometry is a medical and research technique used to measure physical and chemical characteristics of cells or particles, one cell at a time, as they flow in a fluid stream through a beam of light. The properties measured include:

* Cell size (light scatter)
* Cell internal complexity (granularity, also light scatter)
* Presence or absence of specific proteins or other molecules on the cell surface or inside the cell (using fluorescent antibodies or other fluorescent probes)

The technique is widely used in cell counting, cell sorting, protein engineering, biomarker discovery and monitoring disease progression, particularly in hematology, immunology, and cancer research.

Habituation, psychophysiologic, refers to the decrease in autonomic nervous system response to repeated exposure to a stimulus. It is a form of learning that occurs when an individual is exposed to a stimulus repeatedly over time, leading to a reduced reaction or no reaction at all. This process involves the decreased responsiveness of both the sympathetic and parasympathetic branches of the autonomic nervous system.

Examples of psychophysiologic habituation include the decreased heart rate and skin conductance response that occurs with repeated exposure to a startling stimulus, such as a loud noise. This form of habituation is thought to be an adaptive mechanism that allows individuals to respond appropriately to novel or important stimuli while reducing the response to non-significant or irrelevant stimuli.

It's worth noting that habituation can also occur in other systems and contexts, such as sensory habituation (decreased response to repeated sensory stimulation) or cognitive habituation (reduced attention or memory for repeated exposure to a stimulus). However, the term "psychophysiologic habituation" specifically refers to the decreased autonomic nervous system response that occurs with repeated exposure to a stimulus.

In a medical or physiological context, "arousal" refers to the state of being awake and responsive to stimuli. It involves the activation of the nervous system, particularly the autonomic nervous system, which prepares the body for action. Arousal levels can vary from low (such as during sleep) to high (such as during states of excitement or stress). In clinical settings, changes in arousal may be assessed to help diagnose conditions such as coma, brain injury, or sleep disorders. It is also used in the context of sexual response, where it refers to the level of physical and mental awareness and readiness for sexual activity.

'Behavior' is a term used in the medical and scientific community to describe the actions or reactions of an individual in response to internal or external stimuli. It can be observed and measured, and it involves all the responses of a person, including motor responses, emotional responses, and cognitive responses. Behaviors can be voluntary or involuntary, adaptive or maladaptive, and normal or abnormal. They can also be influenced by genetic, physiological, environmental, and social factors. In a medical context, the study of behavior is often relevant to understanding and treating various mental health conditions, such as anxiety disorders, mood disorders, and personality disorders.

Acoustic stimulation refers to the use of sound waves or vibrations to elicit a response in an individual, typically for the purpose of assessing or treating hearing, balance, or neurological disorders. In a medical context, acoustic stimulation may involve presenting pure tones, speech sounds, or other types of auditory signals through headphones, speakers, or specialized devices such as bone conduction transducers.

The response to acoustic stimulation can be measured using various techniques, including electrophysiological tests like auditory brainstem responses (ABRs) or otoacoustic emissions (OAEs), behavioral observations, or functional imaging methods like fMRI. Acoustic stimulation is also used in therapeutic settings, such as auditory training programs for hearing impairment or vestibular rehabilitation for balance disorders.

It's important to note that acoustic stimulation should be administered under the guidance of a qualified healthcare professional to ensure safety and effectiveness.

T-lymphocytes, also known as T-cells, are a type of white blood cell that plays a key role in the adaptive immune system's response to infection. They are produced in the bone marrow and mature in the thymus gland. There are several different types of T-cells, including CD4+ helper T-cells, CD8+ cytotoxic T-cells, and regulatory T-cells (Tregs).

CD4+ helper T-cells assist in activating other immune cells, such as B-lymphocytes and macrophages. They also produce cytokines, which are signaling molecules that help coordinate the immune response. CD8+ cytotoxic T-cells directly kill infected cells by releasing toxic substances. Regulatory T-cells help maintain immune tolerance and prevent autoimmune diseases by suppressing the activity of other immune cells.

T-lymphocytes are important in the immune response to viral infections, cancer, and other diseases. Dysfunction or depletion of T-cells can lead to immunodeficiency and increased susceptibility to infections. On the other hand, an overactive T-cell response can contribute to autoimmune diseases and chronic inflammation.

Operant conditioning is a type of learning in which behavior is modified by its consequences, either reinforcing or punishing the behavior. It was first described by B.F. Skinner and involves an association between a response (behavior) and a consequence (either reward or punishment). There are two types of operant conditioning: positive reinforcement, in which a desirable consequence follows a desired behavior, increasing the likelihood that the behavior will occur again; and negative reinforcement, in which a undesirable consequence is removed following a desired behavior, also increasing the likelihood that the behavior will occur again.

For example, if a child cleans their room (response) and their parent gives them praise or a treat (positive reinforcement), the child is more likely to clean their room again in the future. If a child is buckling their seatbelt in the car (response) and the annoying buzzer stops (negative reinforcement), the child is more likely to buckle their seatbelt in the future.

It's important to note that operant conditioning is a form of learning, not motivation. The behavior is modified by its consequences, regardless of the individual's internal state or intentions.

A Word Association Test is not a medical term per se, but it is a psychological and neuropsychological testing procedure. It is used to assess various aspects of cognitive functioning, particularly language, memory, and executive functions. In this test, the examiner provides a word, and the person being tested is asked to quickly respond with the first word that comes to mind. The responses are then analyzed for any patterns or inconsistencies, which can provide insights into the person's cognitive processes and psychological state.

Word Association Tests have been used in various forms and contexts, including clinical evaluations, research settings, and even in some employment screenings. They can help identify language disorders, memory impairments, thought disorders, and other cognitive or emotional disturbances. However, it's important to note that these tests should be administered and interpreted by trained professionals, as they require a solid understanding of the underlying psychological principles and potential confounding factors.

"Motor activity" is a general term used in the field of medicine and neuroscience to refer to any kind of physical movement or action that is generated by the body's motor system. The motor system includes the brain, spinal cord, nerves, and muscles that work together to produce movements such as walking, talking, reaching for an object, or even subtle actions like moving your eyes.

Motor activity can be voluntary, meaning it is initiated intentionally by the individual, or involuntary, meaning it is triggered automatically by the nervous system without conscious control. Examples of voluntary motor activity include deliberately lifting your arm or kicking a ball, while examples of involuntary motor activity include heartbeat, digestion, and reflex actions like jerking your hand away from a hot stove.

Abnormalities in motor activity can be a sign of neurological or muscular disorders, such as Parkinson's disease, cerebral palsy, or multiple sclerosis. Assessment of motor activity is often used in the diagnosis and treatment of these conditions.

Animal disease models are specialized animals, typically rodents such as mice or rats, that have been genetically engineered or exposed to certain conditions to develop symptoms and physiological changes similar to those seen in human diseases. These models are used in medical research to study the pathophysiology of diseases, identify potential therapeutic targets, test drug efficacy and safety, and understand disease mechanisms.

The genetic modifications can include knockout or knock-in mutations, transgenic expression of specific genes, or RNA interference techniques. The animals may also be exposed to environmental factors such as chemicals, radiation, or infectious agents to induce the disease state.

Examples of animal disease models include:

1. Mouse models of cancer: Genetically engineered mice that develop various types of tumors, allowing researchers to study cancer initiation, progression, and metastasis.
2. Alzheimer's disease models: Transgenic mice expressing mutant human genes associated with Alzheimer's disease, which exhibit amyloid plaque formation and cognitive decline.
3. Diabetes models: Obese and diabetic mouse strains like the NOD (non-obese diabetic) or db/db mice, used to study the development of type 1 and type 2 diabetes, respectively.
4. Cardiovascular disease models: Atherosclerosis-prone mice, such as ApoE-deficient or LDLR-deficient mice, that develop plaque buildup in their arteries when fed a high-fat diet.
5. Inflammatory bowel disease models: Mice with genetic mutations affecting intestinal barrier function and immune response, such as IL-10 knockout or SAMP1/YitFc mice, which develop colitis.

Animal disease models are essential tools in preclinical research, but it is important to recognize their limitations. Differences between species can affect the translatability of results from animal studies to human patients. Therefore, researchers must carefully consider the choice of model and interpret findings cautiously when applying them to human diseases.

In medical terms, the face refers to the front part of the head that is distinguished by the presence of the eyes, nose, and mouth. It includes the bones of the skull (frontal bone, maxilla, zygoma, nasal bones, lacrimal bones, palatine bones, inferior nasal conchae, and mandible), muscles, nerves, blood vessels, skin, and other soft tissues. The face plays a crucial role in various functions such as breathing, eating, drinking, speaking, seeing, smelling, and expressing emotions. It also serves as an important identifier for individuals, allowing them to be recognized by others.

Sleep is a complex physiological process characterized by altered consciousness, relatively inhibited sensory activity, reduced voluntary muscle activity, and decreased interaction with the environment. It's typically associated with specific stages that can be identified through electroencephalography (EEG) patterns. These stages include rapid eye movement (REM) sleep, associated with dreaming, and non-rapid eye movement (NREM) sleep, which is further divided into three stages.

Sleep serves a variety of functions, including restoration and strengthening of the immune system, support for growth and development in children and adolescents, consolidation of memory, learning, and emotional regulation. The lack of sufficient sleep or poor quality sleep can lead to significant health problems, such as obesity, diabetes, cardiovascular disease, and even cognitive decline.

The American Academy of Sleep Medicine (AASM) defines sleep as "a period of daily recurring natural rest during which consciousness is suspended and metabolic processes are reduced." However, it's important to note that the exact mechanisms and purposes of sleep are still being researched and debated among scientists.

Mental processes, also referred to as cognitive processes, are the ways in which our minds perceive, process, and understand information from the world around us. These processes include:

1. Attention: The ability to focus on specific stimuli while ignoring others.
2. Perception: The way in which we interpret and organize sensory information.
3. Memory: The storage and retrieval of information.
4. Learning: The process of acquiring new knowledge or skills.
5. Language: The ability to understand, produce and communicate using words and symbols.
6. Thinking: The process of processing information, reasoning, problem-solving, and decision making.
7. Intelligence: The capacity to understand, learn, and adapt to new situations.
8. Emotion: The ability to experience and respond to different feelings.
9. Consciousness: The state of being aware of and able to think and perceive one's surroundings, thoughts, and feelings.

These mental processes are interconnected and influence each other in complex ways. They allow us to interact with our environment, make decisions, and communicate with others. Disorders in these mental processes can lead to various neurological and psychiatric conditions.

The CA3 region, also known as the field CA3 or regio CA3, is a subfield in the hippocampus, a complex brain structure that plays a crucial role in learning and memory. The hippocampus is divided into several subfields, including the dentate gyrus, CA3, CA2, CA1, and the subiculum.

The CA3 region is located in the cornu ammonis (Latin for "ammon's horn") and is characterized by its distinctive appearance with a high density of small, tightly packed pyramidal neurons. These neurons have extensive branching dendrites that receive inputs from various brain regions, including the entorhinal cortex, other hippocampal subfields, and the septum.

The CA3 region is particularly noteworthy for its involvement in pattern completion, a process by which the brain can recognize and recall complete memories based on partial or degraded inputs. This function is mediated by the recurrent collateral connections between the pyramidal neurons in the CA3 region, forming an autoassociative network that allows for the storage and retrieval of memory patterns.

Deficits in the CA3 region have been implicated in several neurological and psychiatric disorders, including Alzheimer's disease, epilepsy, and schizophrenia.

Repetition priming is a phenomenon in cognitive psychology and neuroscience that refers to the improvement in an individual's ability to recognize or produce a stimulus as a result of having previously encountered it. In other words, repetition priming is the facilitated processing of a stimulus due to its prior presentation.

In the context of medical research and clinical practice, repetition priming has been studied as a potential mechanism underlying various cognitive processes, such as memory, attention, perception, and language. For example, in the field of neuropsychology, researchers have used repetition priming paradigms to investigate the nature of implicit memory in patients with amnesia or other forms of memory impairment.

Repetition priming is typically measured using reaction time or accuracy measures in experimental tasks that involve presenting participants with a series of stimuli, some of which are repeated from earlier in the task. The effect of repetition priming is usually observed as a decrease in reaction time or an increase in accuracy for repeated stimuli compared to new stimuli.

Overall, repetition priming is an important concept in cognitive neuroscience and has implications for our understanding of various aspects of human cognition and behavior.

In a medical context, "orientation" typically refers to an individual's awareness and understanding of their personal identity, place, time, and situation. It is a critical component of cognitive functioning and mental status. Healthcare professionals often assess a person's orientation during clinical evaluations, using tests that inquire about their name, location, the current date, and the circumstances of their hospitalization or visit.

There are different levels of orientation:

1. Person (or self): The individual knows their own identity, including their name, age, and other personal details.
2. Place: The individual is aware of where they are, such as the name of the city, hospital, or healthcare facility.
3. Time: The individual can accurately state the current date, day of the week, month, and year.
4. Situation or event: The individual understands why they are in the healthcare setting, what happened leading to their hospitalization or visit, and the nature of any treatments or procedures they are undergoing.

Impairments in orientation can be indicative of various neurological or psychiatric conditions, such as delirium, dementia, or substance intoxication or withdrawal. It is essential for healthcare providers to monitor and address orientation issues to ensure appropriate diagnosis, treatment, and patient safety.

BALB/c is an inbred strain of laboratory mouse that is widely used in biomedical research. The strain was developed at the Institute of Cancer Research in London by Henry Baldwin and his colleagues in the 1920s, and it has since become one of the most commonly used inbred strains in the world.

BALB/c mice are characterized by their black coat color, which is determined by a recessive allele at the tyrosinase locus. They are also known for their docile and friendly temperament, making them easy to handle and work with in the laboratory.

One of the key features of BALB/c mice that makes them useful for research is their susceptibility to certain types of tumors and immune responses. For example, they are highly susceptible to developing mammary tumors, which can be induced by chemical carcinogens or viral infection. They also have a strong Th2-biased immune response, which makes them useful models for studying allergic diseases and asthma.

BALB/c mice are also commonly used in studies of genetics, neuroscience, behavior, and infectious diseases. Because they are an inbred strain, they have a uniform genetic background, which makes it easier to control for genetic factors in experiments. Additionally, because they have been bred in the laboratory for many generations, they are highly standardized and reproducible, making them ideal subjects for scientific research.

Computer storage devices are hardware components or digital media that store, retain, and retrieve digital data or information. These devices can be classified into two main categories: volatile and non-volatile. Volatile storage devices require power to maintain the stored information and lose the data once power is removed, while non-volatile storage devices can retain data even when not powered.

Some common examples of computer storage devices include:

1. Random Access Memory (RAM): A volatile memory type used as a temporary workspace for a computer to process data. It is faster than other storage devices but loses its content when the system power is turned off.
2. Read-Only Memory (ROM): A non-volatile memory type that stores firmware or low-level software, such as BIOS, which is not intended to be modified or written to by users.
3. Hard Disk Drive (HDD): A non-volatile storage device that uses magnetic recording to store and retrieve digital information on one or more rotating platters. HDDs are relatively inexpensive but have moving parts, making them less durable than solid-state drives.
4. Solid-State Drive (SSD): A non-volatile storage device that uses flash memory to store data electronically without any mechanical components. SSDs offer faster access times and higher reliability than HDDs but are more expensive per gigabyte of storage capacity.
5. Optical Disks: These include CDs, DVDs, and Blu-ray disks, which use laser technology to read or write data on a reflective surface. They have lower storage capacities compared to other modern storage devices but offer a cost-effective solution for long-term archival purposes.
6. External Storage Devices: These are portable or stationary storage solutions that can be connected to a computer via various interfaces, such as USB, FireWire, or Thunderbolt. Examples include external hard drives, solid-state drives, and flash drives.
7. Cloud Storage: A remote network of servers hosted by a third-party service provider that stores data online, allowing users to access their files from any device with an internet connection. This storage solution offers scalability, redundancy, and offsite backup capabilities.

The dentate gyrus is a region of the brain that is located in the hippocampal formation, which is a part of the limbic system and plays a crucial role in learning, memory, and spatial navigation. It is characterized by the presence of densely packed granule cells, which are a type of neuron. The dentate gyrus is involved in the formation of new memories and the integration of information from different brain regions. It is also one of the few areas of the adult brain where new neurons can be generated throughout life, a process known as neurogenesis. Damage to the dentate gyrus has been linked to memory impairments, cognitive decline, and neurological disorders such as Alzheimer's disease and epilepsy.

In the context of medicine and healthcare, "individuality" refers to the unique characteristics, traits, and needs that distinguish one person from another. This concept recognizes that each patient is a distinct individual with their own genetic makeup, lifestyle factors, personal history, and social circumstances, all of which can influence their health status and response to medical interventions.

Individuality in healthcare emphasizes the importance of tailoring medical treatments and care plans to meet the specific needs and preferences of each patient, rather than relying on a one-size-fits-all approach. This personalized approach can lead to better outcomes, improved patient satisfaction, and reduced healthcare costs.

Factors that contribute to an individual's medical individuality include their genetic makeup, epigenetic factors, environmental exposures, lifestyle choices (such as diet, exercise, and substance use), and social determinants of health (such as income, education, and access to care). All of these factors can interact in complex ways to influence a person's health status and risk for disease.

Recognizing and respecting individuality is essential for providing high-quality, patient-centered care. Healthcare providers who take the time to understand their patients' unique needs and preferences are better able to build trust, promote adherence to treatment plans, and achieve positive outcomes.

I must clarify that I cannot provide a "medical definition" of intelligence, as intelligence is not a concept that is typically defined within the field of medicine. Intelligence is a term used to describe the ability to learn, understand, and make judgments or decisions based on reason, experience, and information. It is often measured through various cognitive abilities such as problem-solving, critical thinking, creativity, and knowledge acquisition.

The concept of intelligence is studied in many fields, including psychology, neuroscience, and education. In medicine, healthcare professionals may assess a person's cognitive abilities to better understand their health status or develop treatment plans. However, there is no specific "medical definition" for intelligence. Instead, it is a multifaceted concept that can be influenced by various genetic, environmental, and experiential factors.

Schizophrenia is a severe mental disorder characterized by disturbances in thought, perception, emotion, and behavior. It often includes hallucinations (usually hearing voices), delusions, paranoia, and disorganized speech and behavior. The onset of symptoms typically occurs in late adolescence or early adulthood. Schizophrenia is a complex, chronic condition that requires ongoing treatment and management. It significantly impairs social and occupational functioning, and it's often associated with reduced life expectancy due to comorbid medical conditions. The exact causes of schizophrenia are not fully understood, but research suggests that genetic, environmental, and neurodevelopmental factors play a role in its development.

"Lymnaea" is a genus of freshwater snails, specifically aquatic pulmonate gastropod mollusks. These snails are commonly known as pond snails or ram's horn snails due to their spiral shell shape that resembles a ram's horn. They have a wide global distribution and can be found in various freshwater habitats, such as ponds, lakes, streams, and wetlands.

Some Lymnaea species are known for their use in scientific research, particularly in the fields of neurobiology and malacology (the study of mollusks). For instance, Lymnaea stagnalis is a well-studied model organism used to investigate learning and memory processes at the molecular, cellular, and behavioral levels.

However, it's important to note that "Lymnaea" itself does not have a direct medical definition as it refers to a genus of snails rather than a specific medical condition or disease.

Dementia is a broad term that describes a decline in cognitive functioning, including memory, language, problem-solving, and judgment, severe enough to interfere with daily life. It is not a specific disease but rather a group of symptoms that may be caused by various underlying diseases or conditions. Alzheimer's disease is the most common cause of dementia, accounting for 60-80% of cases. Other causes include vascular dementia, Lewy body dementia, frontotemporal dementia, and Huntington's disease.

The symptoms of dementia can vary widely depending on the cause and the specific areas of the brain that are affected. However, common early signs of dementia may include:

* Memory loss that affects daily life
* Difficulty with familiar tasks
* Problems with language or communication
* Difficulty with visual and spatial abilities
* Misplacing things and unable to retrace steps
* Decreased or poor judgment
* Withdrawal from work or social activities
* Changes in mood or behavior

Dementia is a progressive condition, meaning that symptoms will gradually worsen over time. While there is currently no cure for dementia, early diagnosis and treatment can help slow the progression of the disease and improve quality of life for those affected.

Cell differentiation is the process by which a less specialized cell, or stem cell, becomes a more specialized cell type with specific functions and structures. This process involves changes in gene expression, which are regulated by various intracellular signaling pathways and transcription factors. Differentiation results in the development of distinct cell types that make up tissues and organs in multicellular organisms. It is a crucial aspect of embryonic development, tissue repair, and maintenance of homeostasis in the body.

An epitope is a specific region on an antigen (a substance that triggers an immune response) that is recognized and bound by an antibody or a T-cell receptor. In the case of T-lymphocytes, which are a type of white blood cell that plays a central role in cell-mediated immunity, epitopes are typically presented on the surface of infected cells in association with major histocompatibility complex (MHC) molecules.

T-lymphocytes recognize and respond to epitopes through their T-cell receptors (TCRs), which are membrane-bound proteins that can bind to specific epitopes presented on the surface of infected cells. There are two main types of T-lymphocytes: CD4+ T-cells, also known as helper T-cells, and CD8+ T-cells, also known as cytotoxic T-cells.

CD4+ T-cells recognize epitopes presented in the context of MHC class II molecules, which are typically expressed on the surface of professional antigen-presenting cells such as dendritic cells, macrophages, and B-cells. CD4+ T-cells help to coordinate the immune response by producing cytokines that activate other immune cells.

CD8+ T-cells recognize epitopes presented in the context of MHC class I molecules, which are expressed on the surface of almost all nucleated cells. CD8+ T-cells are able to directly kill infected cells by releasing cytotoxic granules that contain enzymes that can induce apoptosis (programmed cell death) in the target cell.

In summary, epitopes are specific regions on antigens that are recognized and bound by T-lymphocytes through their T-cell receptors. CD4+ T-cells recognize epitopes presented in the context of MHC class II molecules, while CD8+ T-cells recognize epitopes presented in the context of MHC class I molecules.

Interferon-gamma (IFN-γ) is a soluble cytokine that is primarily produced by the activation of natural killer (NK) cells and T lymphocytes, especially CD4+ Th1 cells and CD8+ cytotoxic T cells. It plays a crucial role in the regulation of the immune response against viral and intracellular bacterial infections, as well as tumor cells. IFN-γ has several functions, including activating macrophages to enhance their microbicidal activity, increasing the presentation of major histocompatibility complex (MHC) class I and II molecules on antigen-presenting cells, stimulating the proliferation and differentiation of T cells and NK cells, and inducing the production of other cytokines and chemokines. Additionally, IFN-γ has direct antiproliferative effects on certain types of tumor cells and can enhance the cytotoxic activity of immune cells against infected or malignant cells.

Synaptic transmission is the process by which a neuron communicates with another cell, such as another neuron or a muscle cell, across a junction called a synapse. It involves the release of neurotransmitters from the presynaptic terminal of the neuron, which then cross the synaptic cleft and bind to receptors on the postsynaptic cell, leading to changes in the electrical or chemical properties of the target cell. This process is critical for the transmission of signals within the nervous system and for controlling various physiological functions in the body.

Interleukin-15 (IL-15) is a small protein with a molecular weight of approximately 14 to 15 kilodaltons. It belongs to the class of cytokines known as the four-alpha-helix bundle family, which also includes IL-2, IL-4, and IL-7.

IL-15 is primarily produced by monocytes, macrophages, and dendritic cells, but it can also be produced by other cell types such as fibroblasts, epithelial cells, and endothelial cells. It plays a crucial role in the immune system by regulating the activation, proliferation, and survival of various immune cells, including T cells, natural killer (NK) cells, and dendritic cells.

IL-15 binds to its receptor complex, which consists of three components: IL-15Rα, IL-2/IL-15Rβ, and the common γ-chain (γc). The binding of IL-15 to this receptor complex leads to the activation of several signaling pathways, including the JAK-STAT, MAPK, and PI3K pathways.

IL-15 has a wide range of biological activities, including promoting the survival and proliferation of T cells and NK cells, enhancing their cytotoxic activity, and regulating their differentiation and maturation. It also plays a role in the development and maintenance of memory T cells, which are critical for long-term immunity to pathogens.

Dysregulation of IL-15 signaling has been implicated in various diseases, including autoimmune disorders, chronic inflammation, and cancer. Therefore, IL-15 is a potential target for therapeutic intervention in these conditions.

Malingering is a psychological concept that refers to the deliberate and intentional production or exaggeration of physical or psychological symptoms, motivated by external incentives such as avoiding work or military duty, obtaining financial compensation, or evading criminal prosecution. It's important to note that malingering should be distinguished from other conditions where individuals may experience genuine symptoms but have limited insight into their illness, such as in certain psychiatric disorders.

Malingering is not a mental disorder itself, and it requires careful clinical evaluation to distinguish it from legitimate medical or psychological conditions. It's also worth mentioning that malingering is considered uncommon, and its diagnosis should be made with caution, as it can have significant legal and ethical implications.

Temporal lobe epilepsy (TLE) is a type of focal (localized) epilepsy that originates from the temporal lobes of the brain. The temporal lobes are located on each side of the brain and are involved in processing sensory information, memory, and emotion. TLE is characterized by recurrent seizures that originate from one or both temporal lobes.

The symptoms of TLE can vary depending on the specific area of the temporal lobe that is affected. However, common symptoms include auras (sensory or emotional experiences that occur before a seizure), strange smells or tastes, lip-smacking or chewing movements, and memory problems. Some people with TLE may also experience automatisms (involuntary movements such as picking at clothes or fumbling with objects) during their seizures.

Treatment for TLE typically involves medication to control seizures, although surgery may be recommended in some cases. The goal of treatment is to reduce the frequency and severity of seizures and improve quality of life.

"Cells, cultured" is a medical term that refers to cells that have been removed from an organism and grown in controlled laboratory conditions outside of the body. This process is called cell culture and it allows scientists to study cells in a more controlled and accessible environment than they would have inside the body. Cultured cells can be derived from a variety of sources, including tissues, organs, or fluids from humans, animals, or cell lines that have been previously established in the laboratory.

Cell culture involves several steps, including isolation of the cells from the tissue, purification and characterization of the cells, and maintenance of the cells in appropriate growth conditions. The cells are typically grown in specialized media that contain nutrients, growth factors, and other components necessary for their survival and proliferation. Cultured cells can be used for a variety of purposes, including basic research, drug development and testing, and production of biological products such as vaccines and gene therapies.

It is important to note that cultured cells may behave differently than they do in the body, and results obtained from cell culture studies may not always translate directly to human physiology or disease. Therefore, it is essential to validate findings from cell culture experiments using additional models and ultimately in clinical trials involving human subjects.

Lymphocytic choriomeningitis (LCM) is a viral infectious disease caused by the lymphocytic choriomeningitis virus (LCMV). The infection primarily affects the membranes surrounding the brain and spinal cord (meninges), as well as the cerebrospinal fluid, brain, and spinal cord tissue. It is transmitted to humans through close contact with infected rodents, particularly the house mouse (Mus musculus) or its urine, feces, saliva, or nesting materials.

The symptoms of LCM can vary widely but often include fever, severe headache, stiff neck, sensitivity to light, and sometimes vomiting. In some cases, it may also cause muscle aches, joint pain, and rash. A more severe form of the disease can affect the brain and spinal cord, causing confusion, seizures, or even long-term neurological damage.

LCM is typically diagnosed based on symptoms, laboratory tests, and detection of LCMV in cerebrospinal fluid or blood. Treatment usually involves supportive care to manage symptoms, as there is no specific antiviral therapy available for this infection. Most people with LCM recover completely within a few weeks, but severe cases may require hospitalization and intensive care support.

Preventive measures include avoiding contact with rodents, especially their urine, feces, and saliva, and maintaining good hygiene practices such as washing hands thoroughly after handling animals or being in areas where rodents might be present.

Mild Cognitive Impairment (MCI) is a medical term used to describe a stage between the cognitive changes seen in normal aging and the more serious decline of dementia. It's characterized by a slight but noticeable decline in cognitive abilities, such as memory or thinking skills, that are greater than expected for an individual's age and education level, but not significant enough to interfere with daily life.

People with MCI have an increased risk of developing dementia, particularly Alzheimer's disease, compared to those without MCI. However, it's important to note that not everyone with MCI will develop dementia; some may remain stable, and others may even improve over time.

The diagnosis of MCI is typically made through a comprehensive medical evaluation, including a detailed medical history, cognitive testing, and sometimes brain imaging or laboratory tests.

A lymphocyte count is a laboratory test that measures the number of white blood cells called lymphocytes in a sample of blood. Lymphocytes are a vital part of the immune system and help fight off infections and diseases. A normal lymphocyte count ranges from 1,000 to 4,800 cells per microliter (µL) of blood for adults.

An abnormal lymphocyte count can indicate an infection, immune disorder, or blood cancer. A low lymphocyte count is called lymphopenia, while a high lymphocyte count is called lymphocytosis. The cause of an abnormal lymphocyte count should be investigated through further testing and clinical evaluation.

Olfactory perception refers to the ability to perceive and recognize odors or smells, which is mediated by olfactory receptor neurons located in the nasal cavity. These neurons detect and transmit information about chemical compounds present in the inhaled air to the brain, specifically to the primary olfactory cortex, where the perception of smell is processed and integrated with other sensory inputs. Olfactory perception plays a crucial role in various aspects of human behavior, including food selection, safety, and emotional responses.

Psychological tests are standardized procedures or measures used to assess various aspects of an individual's cognitive functioning, personality traits, emotional status, and behavior. These tests are designed to be reliable and valid tools for evaluating specific psychological constructs such as intelligence, memory, attention, achievement, aptitude, interests, and values. They can be in the form of questionnaires, interviews, observational scales, or performance-based tasks. The results obtained from these tests help mental health professionals make informed decisions about diagnosis, treatment planning, and educational or vocational guidance for their clients. It is important to note that psychological tests should only be administered, scored, and interpreted by trained and qualified professionals to ensure accurate and meaningful results.

Protein synthesis inhibitors are a class of medications or chemical substances that interfere with the process of protein synthesis in cells. Protein synthesis is the biological process by which cells create proteins, essential components for the structure, function, and regulation of tissues and organs. This process involves two main stages: transcription and translation.

Translation is the stage where the genetic information encoded in messenger RNA (mRNA) is translated into a specific sequence of amino acids, resulting in a protein molecule. Protein synthesis inhibitors work by targeting various components of the translation machinery, such as ribosomes, transfer RNAs (tRNAs), or translation factors, thereby preventing or disrupting the formation of new proteins.

These inhibitors have clinical applications in treating various conditions, including bacterial and viral infections, cancer, and autoimmune disorders. Some examples of protein synthesis inhibitors include:

1. Antibiotics: Certain antibiotics, like tetracyclines, macrolides, aminoglycosides, and chloramphenicol, target bacterial ribosomes and inhibit their ability to synthesize proteins, thereby killing or inhibiting the growth of bacteria.
2. Antiviral drugs: Protein synthesis inhibitors are used to treat viral infections by targeting various stages of the viral replication cycle, including protein synthesis. For example, ribavirin is an antiviral drug that can inhibit viral RNA-dependent RNA polymerase and mRNA capping, which are essential for viral protein synthesis.
3. Cancer therapeutics: Some chemotherapeutic agents target rapidly dividing cancer cells by interfering with their protein synthesis machinery. For instance, puromycin is an aminonucleoside antibiotic that can be incorporated into elongating polypeptide chains during translation, causing premature termination and inhibiting overall protein synthesis in cancer cells.
4. Immunosuppressive drugs: Protein synthesis inhibitors are also used as immunosuppressants to treat autoimmune disorders and prevent organ rejection after transplantation. For example, tacrolimus and cyclosporine bind to and inhibit the activity of calcineurin, a protein phosphatase that plays a crucial role in T-cell activation and cytokine production.

In summary, protein synthesis inhibitors are valuable tools for treating various diseases, including bacterial and viral infections, cancer, and autoimmune disorders. By targeting the protein synthesis machinery of pathogens or abnormal cells, these drugs can selectively inhibit their growth and proliferation while minimizing harm to normal cells.

Dendritic spines are small, specialized protrusions found on the dendrites of neurons, which are cells that transmit information in the nervous system. These structures receive and process signals from other neurons. Dendritic spines have a small head connected to the dendrite by a thin neck, and they vary in shape, size, and number depending on the type of neuron and its function. They are dynamic structures that can change their morphology and strength of connections with other neurons in response to various stimuli, such as learning and memory processes.

Anterior Temporal Lobectomy is a surgical procedure that involves the removal of a portion of the anterior (front) part of the temporal lobe of the brain. This procedure is often performed to treat certain types of epilepsy that are resistant to medication, as well as other conditions such as tumors or degenerative diseases that affect this area of the brain.

The temporal lobe is located on each side of the brain and is involved in several important functions, including hearing, memory, emotion, and language comprehension. The anterior portion of the temporal lobe contains structures such as the amygdala and hippocampus, which are critical for the formation and retrieval of memories.

During an anterior temporal lobectomy, a neurosurgeon will make an incision in the skull and remove a portion of the brain tissue that is causing seizures or other symptoms. The size and location of the resection will depend on the specific condition being treated and the individual patient's needs. After the surgery, patients may require rehabilitation to help them recover from any cognitive or physical deficits caused by the procedure.

The fornix, in the context of brain anatomy, is a bundle of nerve fibers that arises from the hippocampus, a major component of the limbic system associated with memory and spatial navigation. The fornix plays a crucial role in conveying information between different parts of the brain.

The fornix has two primary divisions: the precommissural fornix and the postcommissural fornix. The precommissural fornix contains fibers that originate from the hippocampus and the subiculum, while the postcommissural fornix consists of fibers that originate from the septal nuclei and other structures in the limbic system.

The two divisions of the fornix join together to form a structure called the body of the fornix, which then curves around the thalamus and continues as the crura (plural of crus) of the fornix. The crura split into two columns that pass through the interventricular foramen and terminate in the hypothalamus, specifically at the mammillary bodies.

The fornix is an essential structure for memory function, particularly episodic memory (memory of specific events or episodes). Damage to the fornix can result in various cognitive impairments, including memory loss and difficulties with spatial navigation.

In the context of medicine, problem-solving refers to the cognitive process by which healthcare professionals identify, analyze, and address clinical issues or challenges in order to provide optimal care for their patients. This may involve gathering relevant information, generating potential solutions, evaluating their feasibility and risks, selecting the most appropriate course of action, and implementing and monitoring the chosen intervention. Effective problem-solving skills are essential for making informed decisions, improving patient outcomes, and reducing medical errors.

Appetitive behavior is a term used in the field of psychology and neuroscience to refer to actions or behaviors that are performed in order to obtain a reward or positive reinforcement. These behaviors are often driven by basic biological needs, such as hunger, thirst, or the need for social interaction. They can also be influenced by learned associations and past experiences.

In the context of medical terminology, appetitive behavior may be used to describe a patient's level of interest in food or their desire to eat. For example, a patient with a good appetite may have a strong desire to eat and may seek out food regularly, while a patient with a poor appetite may have little interest in food and may need to be encouraged to eat.

Appetitive behavior is regulated by a complex interplay of hormonal, neural, and psychological factors. Disruptions in these systems can lead to changes in appetitive behavior, such as increased or decreased hunger and eating. Appetitive behavior is an important area of study in the field of obesity research, as it is thought that understanding the underlying mechanisms that drive appetitive behavior may help to develop more effective treatments for weight management.

"Wistar rats" are a strain of albino rats that are widely used in laboratory research. They were developed at the Wistar Institute in Philadelphia, USA, and were first introduced in 1906. Wistar rats are outbred, which means that they are genetically diverse and do not have a fixed set of genetic characteristics like inbred strains.

Wistar rats are commonly used as animal models in biomedical research because of their size, ease of handling, and relatively low cost. They are used in a wide range of research areas, including toxicology, pharmacology, nutrition, cancer, cardiovascular disease, and behavioral studies. Wistar rats are also used in safety testing of drugs, medical devices, and other products.

Wistar rats are typically larger than many other rat strains, with males weighing between 500-700 grams and females weighing between 250-350 grams. They have a lifespan of approximately 2-3 years. Wistar rats are also known for their docile and friendly nature, making them easy to handle and work with in the laboratory setting.

In the context of medicine, particularly in neurolinguistics and speech-language pathology, language is defined as a complex system of communication that involves the use of symbols (such as words, signs, or gestures) to express and exchange information. It includes various components such as phonology (sound systems), morphology (word structures), syntax (sentence structure), semantics (meaning), and pragmatics (social rules of use). Language allows individuals to convey their thoughts, feelings, and intentions, and to understand the communication of others. Disorders of language can result from damage to specific areas of the brain, leading to impairments in comprehension, production, or both.

The basal nucleus of Meynert is a collection of neurons located in the substantia innominata, which is a part of the forebrain. These neurons are primarily cholinergic, meaning they release the neurotransmitter acetylcholine. The basal nucleus of Meynert projects to various regions of the cerebral cortex and plays an important role in modulating cognitive functions such as attention, memory, and arousal. Degeneration of these neurons has been implicated in several neurological disorders, including Alzheimer's disease and Parkinson's disease dementia.

Korsakoff syndrome is a neuropsychiatric disorder typically caused by alcohol abuse, specifically thiamine (vitamin B1) deficiency in the brain. It's often associated with Wernicke encephalopathy, and the two together are referred to as Wernicke-Korsakoff syndrome.

The main features of Korsakoff syndrome include severe memory impairment, particularly anterograde amnesia (inability to form new memories), confabulation (making up stories due to gaps in memory), and a lack of insight into their condition. Other cognitive functions like intelligence and perception are usually preserved.

The syndrome is believed to result from damage to the mammillary bodies and other structures in the diencephalon, particularly the thalamus. Treatment involves abstinence from alcohol, thiamine replacement, and a balanced diet. The prognosis varies but often includes some degree of permanent memory impairment.

Intelligence tests are standardized procedures used to assess various aspects of an individual's cognitive abilities, such as their problem-solving skills, logical reasoning, verbal comprehension, and spatial relations. These tests provide a quantitative measurement of intelligence, often reported as an Intelligence Quotient (IQ) score. It is important to note that intelligence is a multifaceted concept, and intelligence tests measure only certain aspects of it. They should not be considered the sole determinant of an individual's overall intellectual capabilities or potential.

"Age factors" refer to the effects, changes, or differences that age can have on various aspects of health, disease, and medical care. These factors can encompass a wide range of issues, including:

1. Physiological changes: As people age, their bodies undergo numerous physical changes that can affect how they respond to medications, illnesses, and medical procedures. For example, older adults may be more sensitive to certain drugs or have weaker immune systems, making them more susceptible to infections.
2. Chronic conditions: Age is a significant risk factor for many chronic diseases, such as heart disease, diabetes, cancer, and arthritis. As a result, age-related medical issues are common and can impact treatment decisions and outcomes.
3. Cognitive decline: Aging can also lead to cognitive changes, including memory loss and decreased decision-making abilities. These changes can affect a person's ability to understand and comply with medical instructions, leading to potential complications in their care.
4. Functional limitations: Older adults may experience physical limitations that impact their mobility, strength, and balance, increasing the risk of falls and other injuries. These limitations can also make it more challenging for them to perform daily activities, such as bathing, dressing, or cooking.
5. Social determinants: Age-related factors, such as social isolation, poverty, and lack of access to transportation, can impact a person's ability to obtain necessary medical care and affect their overall health outcomes.

Understanding age factors is critical for healthcare providers to deliver high-quality, patient-centered care that addresses the unique needs and challenges of older adults. By taking these factors into account, healthcare providers can develop personalized treatment plans that consider a person's age, physical condition, cognitive abilities, and social circumstances.

Listeriosis is an infection caused by the bacterium Listeria monocytogenes. It primarily affects older adults, individuals with weakened immune systems, pregnant women, and newborns. The bacteria can be found in contaminated food, water, or soil. Symptoms of listeriosis may include fever, muscle aches, headache, stiff neck, confusion, loss of balance, and convulsions. In severe cases, it can lead to meningitis (inflammation of the membranes surrounding the brain and spinal cord) or bacteremia (bacterial infection in the bloodstream). Pregnant women may experience only mild flu-like symptoms, but listeriosis can lead to miscarriage, stillbirth, premature delivery, or serious illness in newborns.

It's important to note that listeriosis is a foodborne illness, and proper food handling, cooking, and storage practices can help prevent infection. High-risk individuals should avoid consuming unpasteurized dairy products, raw or undercooked meat, poultry, and seafood, as well as soft cheeses made from unpasteurized milk.

The olfactory pathways refer to the neural connections and structures involved in the sense of smell. The process begins with odor molecules that are inhaled through the nostrils, where they bind to specialized receptor cells located in the upper part of the nasal cavity, known as the olfactory epithelium.

These receptor cells then transmit signals via the olfactory nerve (cranial nerve I) to the olfactory bulb, a structure at the base of the brain. Within the olfactory bulb, the signals are processed and relayed through several additional structures, including the olfactory tract, lateral olfactory striae, and the primary olfactory cortex (located within the piriform cortex).

From there, information about odors is further integrated with other sensory systems and cognitive functions in higher-order brain regions, such as the limbic system, thalamus, and hippocampus. This complex network of olfactory pathways allows us to perceive and recognize various scents and plays a role in emotional responses, memory formation, and feeding behaviors.

I'm sorry for any confusion, but "reading" is not a term that has a specific medical definition. Reading is the activity or process of deciphering and understanding written words or text. It is a fundamental skill in language acquisition and communication, and is not typically used in a medical context unless there is a concern related to reading difficulties or disorders, such as dyslexia. If you have any questions related to medical terminology or health concerns, I'd be happy to try to help answer those for you!

Under declarative memory resides semantic and episodic memory. Semantic memory refers to memory that is encoded with specific ... recover memories Method of loci Mnemonic major system Photographic memory Politics of memory Prenatal memory Procedural memory ... memory that is shared, passed on, and constructed by a group Explicit memory False memory Immunological memory, a ... memory systems that have evolved to help retain survival-and-fitness information Animal memory Body memory, hypothetical memory ...
"SUDAAK - Sudan Memory". www.sudanmemory.org. Retrieved 2022-04-02. "Sudan Memory Team - Sudan Memory". www.sudanmemory.org. ... Khartoum: SFDAS Sudan Memory website Sudan Memory on Facebook Sudan Open Archive by Rift Valley Institute Sudan Archive at ... "Sudan Memory: The project digitising a country's history". Middle East Eye. Retrieved 2023-02-25. "Sudan Memory: Conserving and ... "Mahdia - Sudan Memory". www.sudanmemory.org. Retrieved 2022-04-02. "Sharhabil Ahmed - Sudan's King of Jazz - Sudan Memory". www ...
... may refer to: Atkinson-Shiffrin memory model Baddeley's model of working memory Memory-prediction model Memory ... addressing scheme for computer memory address space Flat memory model Paged memory model Segmented memory One of the x86 memory ... describes how threads interact through memory Java memory model Consistency model Memory model (addressing scheme), an ... models This disambiguation page lists articles associated with the title Memory model. If an internal link led you here, you ...
An automatic channel memory system (ACMS) is a system in which a digitally controlled radio tuner such as a TV set or VCR could ... While early sets often lost their memory in a power outage or by otherwise being disconnected from mains electricity, all of ... without affecting memory. A typical TV device allows an automatic channel scan to be performed from a menu accessed by a button ...
... is accessed when a touch probe comes into contact with a memory button. Read and/or write operations between the ... Touch Memory (or contact memory) is an electronic identification device packaged in a coin-shaped stainless steel container. ... Communication rate, and product breadth, of touch memory goes well beyond the simple memory products typically available with ... Touch memory is used in such areas as Access control Asset management eCash Gaming systems Thermochron applications Time and ...
In computing, memory ballooning is a technique used to eliminate the need to overprovision host memory used by a virtual ... which allocates unused memory within the VM's address space into a reserved memory pool (the "balloon") so that it is ... However, rather than being reserved for other uses within the VM, the physical memory mapped to those pages within the VM is ... Depending on the amount of memory required by the VM, the size of the "balloon" may be increased or decreased dynamically, ...
World Memory Championships website World Memory Olympics website USA National Memory Championships Memory Ladder - for Android ... International Association of Memory". www.iam-memory.org. Retrieved 2017-12-07. "World Memory Championships , World Memory ... Eidetic memory Exceptional memory Haraguchi's mnemonic system Interference theory Linkword Memory Memory League Mentalism ... Memory sport, sometimes referred to as competitive memory or the mind sport of memory, refers to competitions in which ...
... and episodic memory are both types of explicit memory (or declarative memory), or memory of facts or events ... Semantic memory is distinct from episodic memory-the memory of experiences and specific events that occur in one's life that ... Other research suggests that both semantic memory and episodic memory are part of a singular declarative memory system, yet ... The use of semantic memory differs from episodic memory: semantic memory refers to general facts and meanings one shares with ...
... is the act of enhancing one's memory. Research on improving memory is driven by amnesia, age-related memory ... Cognitive enhancer Effect of caffeine on memory Emotion and memory Music-related memory Sleep and Memory Spaced repetition ... A memory clamp (also called a "reality clamp") is a generic name for a type of physical memory aid designed be worn on the ... Typical memory aids for people with Alzheimer's includes sticky notes and color-coded memory aids. Tying a string around one's ...
... s work by monitoring memory access, allocations, and deallocation of memory. Many memory debuggers require ... A memory debugger is a debugger for finding software memory problems such as memory leaks and buffer overflows. These are due ... Some memory debuggers (e.g. Valgrind) work by running the executable in a virtual machine-like environment, monitoring memory ... As abnormally high memory utilization can be a contributing factor in software aging, memory debuggers can help programmers to ...
... , also known as folklore or myths, refers to past events that have been passed orally from generation to generation ... The events described by the memories may date back hundreds, thousands, or even tens of thousands of years and often have a ... Bruemmer, Fred (1993). Arctic memories: living with the Inuit. Key Porter Books. p. 37. ISBN 1550134612. Retrieved 2015-06-24. ... suggesting the memory of the proboscideans had become conflated with that of other megafauna, such as bears and sabertooths. ...
... s, also called fixed-size blocks allocation, is the use of pools for memory management that allows dynamic memory ... Free list Object pool Slab allocation Fast Efficient Fixed-Sized Memory Pool PJLIB Reference: Fast Memory Pool A Memory ... Benefits Memory pools allow memory allocation with constant execution time. The memory release for thousands of objects in a ... This is also known as a region; see region-based memory management. A simple memory pool module can allocate, for example, ...
... see external memory (psychology) For the use of the term in computing, see auxiliary memory For the use of the term in computer ... see external memory algorithm This disambiguation page lists articles associated with the title External memory. If an internal ... The term external memory is used with different meanings in different fields: For the use of the term in psychology, ...
... can also be divided into egocentric and allocentric spatial memory. A person's spatial memory is required to ... Spatial memory has representations within working, short-term memory and long-term memory. Research indicates that there are ... The evidence for the spatial memory of some species of animals, such as rats, indicates that they do use spatial memory to ... Sleep deprivation hinders memory performance improvement due to an active disruption of spatial memory consolidation. As a ...
For a memory technology to be considered a universal memory, it would need to have best characteristics of several memory ... resistive random-access memory (RRAM) nano-RAM memristor-based memory Since each memory has its limitations, none of these have ... bubble memory (1970-1980, obsolete) racetrack memory (currently experimental) ferroelectric random-access memory (FRAM) (in ... Many types of memory technologies have been explored with the goal of creating a practical universal memory. These include: low ...
... a type of computer memory used in certain very high speed searching applications Autoassociative memory, all computer memories ... Associative memory may refer to: Associative memory (psychology), the ability to learn and remember the relationship between ... that enable one to retrieve a piece of data from only a tiny sample of itself Bidirectional associative memory, a type of ... for a fuzzy match across a broad field This disambiguation page lists articles associated with the title Associative memory. If ...
... is Nevermore's only EP. It was recorded in April and May 1996 and released on July 23, 1996. It features a Bauhaus ... In Memory at AllMusic Albrecht, Frank. "Rock Hard". issue 110. Retrieved 20 May 2013. v t e (Articles with short description, ...
... constitute a central element to the politics of memory and impact on the culture of historical memory and culture ... Memory laws can be either punitive or non-punitive. A non-punitive memory law does not imply a criminal sanction. It has a ... A punitive memory law includes a sanction, often of a criminal nature. Nikolai Koposov refers to "memory laws per se" as "laws ... Scholars of memory laws have pointed to the proliferation and promulgation of memory laws in the past decade within the member ...
Physical Address Extension (PAE) Virtual Memory I: the problem High Memory Virtual Memory I: the problem (Articles with short ... of virtual memory to use. On computers with a lot of physical memory, this can mean that there exists memory that the kernel ... High memory is the part of physical memory in a computer which is not directly mapped by the page tables of its operating ... When the kernel wishes to address high memory, it creates a mapping on the fly and destroys the mapping when done, which incurs ...
"Loving Memory - Blu-ray Tony Scott". www.dvdbeaver.com. Loving Memory at IMDb Loving Memory at Rotten Tomatoes v t e (Use dmy ... Loving Memory is a 1970 black and white psychological drama film written and directed by Tony Scott, credited as Anthony Scott ... "Loving Memory (1970)". Archived from the original on 2 January 2018. Baxter, Brian (24 August 2012). "How Tony Scott ... "Pete's Peek - The BFI unearths Tony Scott's debut, Loving Memory - Movie Talk - What's on TV". 28 August 2010. "BFI ...
Adding complexity slows down the memory hierarchy. CMOx memory technology stretches the Flash space in the memory hierarchy One ... cache Cache hierarchy in a modern processor Memory wall Computer memory Hierarchical storage management Cloud storage Memory ... main memory to disk). Modern programming languages mainly assume two levels of memory, main memory and disk storage, though in ... The type of memory or storage components also change historically. For example, the memory hierarchy of an Intel Haswell Mobile ...
The term memory is also often used to refer to non-volatile memory including read-only memory (ROM) through modern flash memory ... NMOS memory was commercialized by IBM in the early 1970s. MOS memory overtook magnetic core memory as the dominant memory ... Memory geometry Memory hierarchy Memory organization Processor registers store data but normally are not considered as memory, ... Examples of non-volatile memory are flash memory and ROM, PROM, EPROM and EEPROM memory. Examples of volatile memory are ...
Official website History & Memory at JSTOR History & Memory at Project MUSE (Articles with short description, Short description ... "Collective Memory and Historical Consciousness." History and Memory 1.1 (1989): 5-26. He, Yinan. "Remembering and Forgetting ... "Transcultural Memory and the Troostmeisjes/Comfort Women Photographic Project." History and Memory 30.1 (2018): 116-150. Myers ... Maier, Charles S. "A Surfeit of Memory? Reflections on History, Melancholy and Denial." History and Memory 5.2 (1993): 136-152 ...
... is the recording of memories outside the brain. The earliest forms of symbolic behavior-scratching marks on ... However it was the invention of writing that allowed complex memories to be recorded. A more narrow meaning of exosomatic ... Brain-computer interface "INLS 302: Newby on Cognitive Space". (Memory). ... memory is a computerized information system that interfaces directly with the brain and functions as an extension of the user ...
A digital computer's main memory consists of many memory locations. Each memory location has a physical address which is a code ... Base address Endianness Low-level programming language Memory address register Memory allocation Memory management unit (MMU) ... shared memory and memory mapped files. Some parts of address space may be not mapped at all. Some systems have a "split" memory ... number of physical memory connectors or amount of soldered-on memory). Each memory location in a stored-program computer holds ...
... may refer to: A computer memory component or device. Xbox 360 memory units, flash-based memory devices Memory cards ... in video game consoles This disambiguation page lists articles associated with the title Memory unit. If an internal link led ...
Many early computers, called drum computers or drum machines, used drum memory as the main working memory of the computer. Some ... CAB500 Carousel memory (magnetic rolls) Karlqvist gap Manchester Mark 1 Random-access memory Wisconsin Integrally Synchronized ... Drums were displaced as primary computer memory by magnetic core memory, which offered a better balance of size, speed, cost, ... deriving from the use of drum secondary-storage devices as backup storage for pages in virtual memory. Magnetic drum memory ...
"Black Memory". "» Movie Review: BLACK MEMORY (1947)". Black Memory at IMDb v t e (Use dmy dates from May 2016, Use British ... Black Memory is a 1947 British crime film directed by Oswald Mitchell and starring Michael Atkinson, Myra O'Connell and Michael ... Also making her film acting debut in Black Memory was the Welsh-born actor, playwright, screenwriter and film director Jane ... "Black Memory (1947)". Archived from the original on 17 August 2016. "Arden, Jane (1927-82)". Screen Online. " ...
Semantic memory Declarative memory Sensory memory Visual memory Spatial memory A. Jansen, A.; Sehlmeyer, C.; Pfleiderer, B.; ... Verbal memory is a term used in cognitive psychology which refers to memory of words and other abstractions involving language ... Articles with short description, Short description matches Wikidata, Memory). ... Sommer, J.; Konrad, C.; Zwitserlood, P.; Knecht S. "Assessment of Verbal Memory by fMRI: Lateralization and Functional ...
... is a Los Angeles Historic-Cultural Monument (HCM #155) located in the Wilmington section of Los Angeles, ... "Plaque Ceremonies At Memory Chapel". Wilmington Daily Press Journal. April 4, 1946. p. 4 - via Newspapers.com. "Wilmington". LA ... 155 - Memory Chapel". Big Orange Landmarks. 2008-06-19. (Articles with short description, Short description matches Wikidata, ... English services are held in the adjacent Calvary Presbyterian Church-which replaced the Memory Chapel. List of Los Angeles ...
Remote memory techniques for datacenter applications have recently gained a great deal of popularity. Existing remote memory ... Canvas is a redesigned swap system that fully isolates swap paths for remote-memory applications. Canvas allows each ... However, when multiple applications co-run on a remote-memory system, significant interference could occur, resulting in ... title = {Canvas: Isolated and Adaptive Swapping for {Multi-Applications} on Remote Memory},. booktitle = {20th USENIX Symposium ...
Occurs when a block of memory is allocated but not deallocated within a specific time segment during application execution. ... Invalid Memory Access Invalid Partial Memory Access Lock Hierarchy Violation Memory Growth Memory Leak Memory Not Deallocated ... Intel Inspector distinguishes among Memory leak, Memory not deallocated, and Memory growth problem types in the following ... Memory Growth. Occurs when a block of memory is allocated but not deallocated within a specific time segment during application ...
... memory bandwidth and system memory allocation/de-allocation, identify high bandwidth issues and NUMA issues in your memory- ... Memory Usage View. Use the Intel® VTune™ Profiler to analyze cache misses (L1/L2/LLC), memory loads/stores, memory bandwidth ... For memory objects data, click the Bottom-up tab and select a grouping level containing Memory Object or Memory Object ... Memory Usage View Analyze Topology, Memory, and Cross-Socket Bandwidth View Performance Metrics by Memory Objects (Linux* ...
Memory by Lois McMaster Bujold Review by Wendy Kosak If youre already a Miles Vorkosigan fan, I suspect that wild horses could ... Illyan falls victim to sabotage to his bio memory chip. At this point, the novel becomes a murder mystery. While it is ...
While state-dependent memory may seem rather similar to context-dependent memory, context-dependent memory involves an ... It can affect your memory for where you left your car keys. However, the power of state-dependent memory can also be harnessed ... Alcoholism can enhance state-dependent memory as well. In a study comparing the state-dependent memory effects of alcohol on ... State-dependent memory has widespread effects that can play roles in our everyday lives.[9][10][11][12][18] For example, state- ...
... memory." But memory modification didnt work that way. If you knew a rosy memory was rosy, you wouldnt buy it. The memory had ... Manipulations of memory were "assaults on its very essence," she wrote. "We should worry about whose memory is next. Memory, ... childhood memories in the case of Disney, college memories in the case of beer. They noted that since memory was fallible and ... The memory doctors I had speculated about in 1980 were supposed to use their talents to help people. The memory doctors of the ...
Memory corruption involving scrolling. Announced. September 17, 2013. Reporter. Nils. Impact. Critical. Products. Firefox, ... Security researcher Nils reported two potentially exploitable memory corruption bugs involving scrolling. The first was a use- ...
Under declarative memory resides semantic and episodic memory. Semantic memory refers to memory that is encoded with specific ... recover memories Method of loci Mnemonic major system Photographic memory Politics of memory Prenatal memory Procedural memory ... memory that is shared, passed on, and constructed by a group Explicit memory False memory Immunological memory, a ... memory systems that have evolved to help retain survival-and-fitness information Animal memory Body memory, hypothetical memory ...
5.2 introduces a persistent memory feature that can "remember" script-defined variables and functions across executions; pass ... This supplementary manual provides an in-depth look at persistent-memory gawk. . ... variables between unrelated scripts without serializing/parsing text files; and handle data sets larger than available memory ...
... you can increase the maximum virtual memory on your Windows system. ... To ensure that you have sufficient memory to deploy models and perform other processes like sending and receiving events, ... To prevent out-of-memory errors, the paging file on your Windows system must be at maximum size. To increase the virtual memory ... Tuning your Windows virtual memory settings. To ensure that you have sufficient memory to deploy models and perform other ...
The cache augments, and is an extension of, a computers main memory. ... supplementary memory system that temporarily stores frequently used instructions and data for quicker processing by the central ... The cache augments, and is an extension of, a computers main memory. Both main memory and cache are internal random-access ... If the information is not in the cache, the CPU retrieves it from the main memory. Disk cache memory operates similarly, but ...
Memory analysis is the decisive victory on the battlefield between offense and defense, giving the upper hand to incident ... Memory analysis is the decisive victory on the battlefield between offense and defense, giving the upper hand to incident ...
Brain HSE Memory RAM Safe for Work?. Yes. Download. SVG (Vector) PNG (Bitmap) Small Medium Large ... Working Memory. by gcastano - uploaded on July 3, 2014, 7:11 pm ... Graphic representing the working memory as a RAM section inside ...
The Memory Division provides comprehensive diagnostic and treatment services for Alzheimers disease and other types of ... Memory Disorders Coordinator Phone: 617-726-1728. Mailing Address. Department of Neurology. Memory Disorders Unit. Mail code: ... Memory Disorders Division. The Memory Division provides comprehensive diagnostic and treatment services for Alzheimers disease ... Treating the Whole Family - Memory Disorders Care at Mass General Hospital Memory Disorders Unit Director Teresa Gomez-Isla, MD ...
... wants to increase the memory in workstations and servers without driving up system costs. ... Instead of the memory chips communicating directly to the memory controller, that communication is now routed through the chip ... He said that as the use of virtualization and "in-memory" databases increase, the burden to add more memory into each system ... "CPUs had continued to scale over the last 10 years, but what we both saw was that the memory system had not kept pace with the ...
... a Nobel Prize winner and neuroscience rock star whose study of memorys synaptic manifestation revolutioni ... Biology and psychology collide thanks to Eric Kandel, a Nobel Prize winner and neuroscience rock star whose study of memorys ...
Memory keeps a record of what has made someone uneasy or upset, what undercut a persons sense of self-worth, what brought ... Memories can be immensely powerful, and for people struggling with mental health conditions, that power can be a burden. ... Trauma and Memory Memory extends the reach of traumatic experiences-shocks to the system such as acts of violence or abuse or a ... Memories can be immensely powerful, and for people struggling with mental health conditions, that power can be a burden. Memory ...
Re: Memory corruption (?) I dont understand BERTRAND Joël Tue, 22 Jun 2021 10:40:08 -0700 ... If there is a memory corruption somewhere, I could understand that a debug trace _before_ the line that triggers the bug can ...
Memory Walk is a series of sponsored walks for all ages and abilities to unite together and raise money to support anyone ... What is Memory Walk?. Memory Walk is a series of sponsored walks held in September and October across the UK. Its free to sign ... Feel it all at Memory Walk. The buzz of the crowd, quiet moments of remembrance, the hug of a stranger who gets it - whatever ... Find your nearest Memory Walk to walk for anyone affected by dementia. ...
Zend Memory Manager. The solution to memory leaks during request bailout is the Zend Memory Management (ZendMM) layer. This ... memory_limit. . If a script attempts to ask for more memory than is available to the system as a whole, or more than is ... would leak some memory every time it was called. Eventually the web server process would own all the system memory, but not be ... This is no great feat as the OS knows which program it gave that memory to, and it can be certain that the memory is no longer ...
Find the best memory foam mattresses from top brands like Beautyrest only at JCPenney. Shop for the mattresses at discounted ... Memory Foam Pillows for A Good Nights Sleep. Now that youve picked out your new memory foam mattress or topper, its time to ... A memory foam pillow with the right density will support your neck and head, helping with spinal alignment. We have a fantastic ... Shop Comfortable Memory Foam Mattresses Only at JCPenney. Youve probably heard the phrase, "a good nights sleep." In todays ...
A practical guide to enhancing your digital investigations with cutting-edge memory forensics techniques ... Find me in memory. Lets start with malware that works exclusively in memory. The concept itself is not new. When talking about ... Discovering the challenges of memory forensics. We hope you have already realized the importance of memory analysis. Now it is ... Memory is a great source of forensic artifacts in the hands of an experienced investigator. Memory analysis provides ...
var_dump(memory_get_peak_usage());. $a = str_repeat("Hello", 424242);. var_dump(memory_get_peak_usage());. unset($a);. memory_ ... Resets the peak memory usage returned by the memory_get_peak_usage() function. ... memory_get_peak_usage() - Returns the peak of memory allocated by PHP ... Example #1 memory_reset_peak_usage() example. ,?php. ... memory_reset_peak_usage. (PHP 8 ,= 8.2.0). memory_reset_peak_ ...
Memory loss associated with marijuana use is caused by the drugs interference with the brains natural protein synthesis ... How Marijuana Causes Memory Deficits. Date:. August 4, 2009. Source:. Nature Medicine. Summary:. Memory loss associated with ... Though it has been documented that marijuana impairs memory, the precise mechanism for this memory impairment was previously ... "How Marijuana Causes Memory Deficits." ScienceDaily. www.sciencedaily.com. /. releases. /. 2009. /. 08. /. 090803123240.htm ( ...
Memory Management¶. Linux memory management subsystem is responsible, as the name implies, for managing the memory in the ... This includes implementation of virtual memory and demand paging, memory allocation both for kernel internal structures and ... Linux memory management has its own jargon and if you are not yet familiar with it, consider reading Concepts overview. ... Linux memory management is a complex system with many configurable settings. Most of these settings are available via /proc. ...
ol, ,li,Random Access Memory (RAM) is a type of computer memory that can be accessed randomly. This means any byte of memory ... Q: What is Random Access Memory (RAM)?A: Random Access Memory, usually shortened to RAM, is a type of computer memory that can ... Random Access Memory, often abbreviated as RAM, refers to a type of computer memory that can be accessed randomly, meaning any ... 1. Personal Computers: The laptops and desktops we use everyday have Random Access Memory (RAM). Its the short-term memory ...
Im running RH9 with KDE 3.1 and the system monitor is showing that 240 megs of memory is being used after a fresh reboot I ... It works differently (and better) than the popular OS memory management.. # Memory and swap information. free. An article: Tips ... red hat 9 is a memory hog, can i put it on a diet? set235. Red Hat. 14. 10-17-2003 04:26 AM. ... What am I missing? Are there other processes that I am not aware of that take up huge ammounts of memory or is this just part ...
0.5 percent for SDRAM memory controllers or other non-memory chip components, and 1 percent for DDR SDRAM memory controllers ... The announcement followed allegations that Rambus convinced industry groups to declare a standard technology for the memory ... "is designed to remedy the effects of the unlawful monopoly Rambus established in the markets for four computer memory ...
Get great deals on Medium Memory Foam Mattresses when you shop the huge selection at eBay.com. See why eBay is the best place ... Ssecretland 8 Inch Queen Size Memory Foam Mattress More Breathable Bed Comfortable Mattress ...
  • Explicit knowledge of the world is a form of declarative memory , which can be broken down further into semantic memory , and episodic memory , which encompasses both autobiographical memory and event memory. (wikipedia.org)
  • Under declarative memory resides semantic and episodic memory. (wikipedia.org)
  • Meanwhile, episodic memory refers to information that is encoded along a spatial and temporal plane. (wikipedia.org)
  • Each kind of memory has distinct uses-from the vivid recollections of episodic memory to the functional know-how of procedural memory. (psychologytoday.com)
  • Declarative memory provides the critical substrate for relational representations-i.e., for spatial, temporal, and other contextual relations among items, contributing to representations of events (episodic memory) and the integration and organization of factual knowledge (semantic memory). (nih.gov)
  • The type of knowledge that is stored in implicit memory is called implicit knowledge , implicit memory's counterpart is known as explicit memory or declarative memory, which refers to the conscious , intentional recollection of factual information, previous experiences and concepts. (wikipedia.org)
  • Declarative memory is usually the primary process thought of when referencing memory. (wikipedia.org)
  • Declarative memory is the acquisition or encoding, storage and consolidation, and retrieval of representations of facts and events. (nih.gov)
  • Memory loss is usually described as forgetfulness or amnesia. (wikipedia.org)
  • Memory disorders also include multiple types of amnesia that result not from diseases such as Alzheimer's, but from brain injury or other causes. (psychologytoday.com)
  • In some cases the memory loss is permanent, but there are also temporary forms of amnesia that resolve on their own. (psychologytoday.com)
  • Amnesia, or abnormal memory loss, can also result from a range of other medical conditions, sudden brain injury, substance use, or in reaction to a traumatic event. (psychologytoday.com)
  • Amnesia is a substantial loss of memory, including diminished ability to remember the past, to create new memories, or both. (psychologytoday.com)
  • Amnesia can have many possible causes and encompasses various manifestations of memory loss, including sudden and temporary forms as well as gradual and permanent losses, as in dementia. (psychologytoday.com)
  • Amnesia can include problems with both the retrieval of previously formed memories and the formation of new ones. (psychologytoday.com)
  • You may have heard about a memory problem called amnesia (say: am-NEE-zhuh). (kidshealth.org)
  • Complete amnesia, often spanning hours, is known as an "en bloc" blackout. (nih.gov)
  • Also, the storage process can become corrupted by physical damage to areas of the brain that are associated with memory storage, such as the hippocampus. (wikipedia.org)
  • Yet there are commonalities in how memory works overall, and key brain structures, such as the hippocampus, that are integral to different kinds of memory. (psychologytoday.com)
  • Dementia involves damage to parts of the brain that are important for memory, including the hippocampus and the frontal lobes . (psychologytoday.com)
  • The hippocampus (say: hih-puh-KAM-pus) is one of the more important parts of the brain that processes memories. (kidshealth.org)
  • The brain's hippocampus region is critical for creating a memory, but long-term storage of a memory-called memory consolidation-is thought to involve interactions between the hippocampus and parts of the brain's cortex. (nih.gov)
  • These results strongly suggest that the hippocampus and a portion of the lateral occipital complex coordinate to replay recent experiences during periods of rest in order to consolidate memories. (nih.gov)
  • These gaps happen when a person drinks enough alcohol to temporarily block the transfer of memories from short-term to long-term storage-known as memory consolidation-in a brain area called the hippocampus. (nih.gov)
  • An example of a non-declarative process would be the unconscious learning or retrieval of information by way of procedural memory, or a priming phenomenon. (wikipedia.org)
  • Priming is the process of subliminally arousing specific responses from memory and shows that not all memory is consciously activated, whereas procedural memory is the slow and gradual learning of skills that often occurs without conscious attention to learning. (wikipedia.org)
  • However, early memories are notoriously sparse from the perspective of an adult trying to recall his or her childhood in depth. (wikipedia.org)
  • Contrary to previous research, newer research has shown that children can recall specific episodic memories for up to two years prior to the onset of the earliest autobiographical memories reported by adults. (wikipedia.org)
  • Tests of very young children and adults show that in all age groups, memory recall shows the same sequential cause-and-effect pattern. (wikipedia.org)
  • [ 1 ] Memory loss, especially delayed recall, [ 2 ] can signal the onset of dementia and often leads to institutionalization and a decrease in the quality of life. (medscape.com)
  • Short-term memory, not to be confused with working memory, allows recall for a period of several seconds to a minute without rehearsal. (wikipedia.org)
  • Those receiving the high soya diet showed significant improvements in short-term (immediate recall of prose and 4-s delayed matching to sample of patterns) and long-term memory (picture recall after 20 min) and in mental flexibility (rule shifting and reversal). (researchgate.net)
  • Preliminary research shows that daily intake of 300 mg of Nutrilite's standardized Cistanche tubulosa may improve memory, focus, and recall in healthy people over a longer period of time, sustained over a period of weeks. (prnewswire.com)
  • There is some evidence that listening to music from one's youth and exposure to visual reminders may help a person with dementia recall and talk about memories of the past that would otherwise not arise in conversation. (psychologytoday.com)
  • Hallucinogens (like LSD or PCP) can alter certain chemicals in the brain that actually make memories harder to recall. (kidshealth.org)
  • Semantic memory refers to memory that is encoded with specific meaning. (wikipedia.org)
  • The working memory also retrieves information from previously stored material. (wikipedia.org)
  • Memory is the faculty by which the brain encodes, stores, and retrieves information. (psychologytoday.com)
  • If retrieves the memory usage either in percent (without the percent sign) or in bytes by returning an array with free and overall memory of your system. (php.net)
  • Until relatively recently, it was thought that children have only a very general memory and that "overwrite mechanisms" prevented the later retrieval of early memories. (wikipedia.org)
  • Working memory serves as an encoding and retrieval processor. (wikipedia.org)
  • Finally, the retrieval of information from long-term memory can be disrupted because of decay within long-term memory. (wikipedia.org)
  • The team ran a second experiment in which caffeine wasn't administered until one hour before the memory test, to check for any effects on memory retrieval. (newscientist.com)
  • Nonvolatile memory can hold information without any electrical current. (informit.com)
  • Nonvolatile memory, because it is not volatile, stays the same without any need for electricity. (informit.com)
  • This is why more permanent data is stored in nonvolatile memory such as magnetic hard disks in computers and Flash memory in cell phones. (technologyreview.com)
  • Neurophysiological mechanisms of implicit and explicit memory in the process of consciousness. (nih.gov)
  • Evidence for implicit memory arises in priming , a process whereby subjects are measured by how they have improved their performance on tasks for which they have been subconsciously prepared. (wikipedia.org)
  • [3] [4] Implicit memory also leads to the illusory truth effect , which suggests that subjects are more likely to rate as true those statements that they have already heard, regardless of their truthfulness. (wikipedia.org)
  • Advanced studies of implicit memory began only in the 1980s. (wikipedia.org)
  • The effect of implicit memory was tested employing priming procedures. (wikipedia.org)
  • [1] Several studies confirm implicit memory as a separate entity. (wikipedia.org)
  • Some clues as to the anatomical basis of implicit memory have emanated from recent studies comparing different forms of dementia. (wikipedia.org)
  • 1988). This possible double dissociation involving HD and DAT patients suggests that different implicit memory tasks are mediated by distinct neural systems and that these tasks can be used to differentiate some of the so-called "cortical" (e.g. (wikipedia.org)
  • Memory is often understood as an informational processing system with explicit and implicit functioning that is made up of a sensory processor, short-term (or working) memory, and long-term memory. (wikipedia.org)
  • Information in the form of stimuli is encoded in accordance with explicit or implicit functions by the working memory processor. (wikipedia.org)
  • Non-declarative, or implicit, memory is the unconscious storage and recollection of information. (wikipedia.org)
  • 10/28/2022 Memory devices combining fast read performance up to 133MHz with fast program and erase times. (mouser.com)
  • People with dementia experience a progressive loss of function, such that memory loss may begin with minor forgetfulness (about having recently shared a story, for example) and gradually progress to difficulty with retaining new information, recognizing familiar individuals, and other important memory functions. (psychologytoday.com)
  • Alliance Memory features a SRAM line-up that includes densities ranging from 64k to 16M Fast SRAM and 64k to 32M low-power (LP) SRAM, in both x8 and x16 configurations. (mouser.com)
  • The Monkey Head Mushroom and Memory Enhancement in Alzheimer's Disease. (nih.gov)
  • In addition to Alzheimer's disease, frontotemporal dementia, vascular dementia, and other conditions cause memory loss. (psychologytoday.com)
  • But some memory problems are serious, such as when a person has Alzheimer's disease . (kidshealth.org)
  • More significant problems with memory, such as in Alzheimer's disease, might make it hard to remember what happened days, weeks, months, or even years ago, and it can be difficult to learn and remember new things. (kidshealth.org)
  • For example, if a thread holds a pointer to the heap, and another thread releases the memory back to the heap, then all future accesses to this memory are invalid. (intel.com)
  • The heap typically uses operating system functions to manage its memory. (oreilly.com)
  • Memory Analysis is a QNX tool that uses the debug version of the memory allocation library ( librcheck.so ) to track heap memory, validate pointer arguments to C library functions, and detect memory corruption. (qnx.com)
  • Memories grow stronger when people take a break to rest, according to a new study. (nih.gov)
  • Researchers have discovered the active compound from an edible mushroom that boosts nerve growth and enhances memory. (sciencedaily.com)
  • Researchers strongly suspected that caffeine enhances memory, but studies that tried to show this in people weren't conclusive, as any apparent benefits in memory could have been due to increased attention, a known benefit of caffeine. (newscientist.com)
  • Studies in animals such as rats, meanwhile, suggested that it enhances memory consolidation - the process of strengthening memories between acquiring them and retrieving them - which should affect long-term memory. (newscientist.com)
  • What role, if any, should physicians play in helping bridge potential gaps of communication, taking into consideration how some patients re-live their own personal memories of mistreatment within spaces of healthcare? (nih.gov)
  • Scientists believe that memories are "replayed," with the brain reactivating the same patterns of activity as during the experience itself. (nih.gov)
  • Most neuroscientists believe that memories occur when you change the strength of synaptic connections," Sossin told LiveScience . (livescience.com)
  • Most people have no memory prior to three years of age, and few memories between three and six years of age, as verified by analysis of the forgetting curve in adults recalling childhood memories. (wikipedia.org)
  • Forgetting may seem to move backward in time , beginning with recent events and ultimately affecting memories from many years earlier. (psychologytoday.com)
  • Much memory study focuses on associative memory , or memories formed between two entities, linking them together in the brain. (wikipedia.org)
  • The experimental psychologist and cognitive neuroscientist Endel Tulving refers to memory as "mental time travel", a process unique to humans. (wikipedia.org)
  • Long-term memory stores it for a longer period of time. (medlineplus.gov)
  • Normal functioning, decay over time, and brain damage all affect the accuracy and capacity of the memory. (wikipedia.org)
  • Size of the largest contiguous free memory block, which is an upper bound on the size of the largest array MATLAB can create at this time. (mathworks.com)
  • Short-term memory tricks include mnemonic devices (such as acronyms and categorization), spacing apart study time, and self-testing for the sake of recalling information. (psychologytoday.com)
  • While the degree of memory loss depends on the progression of the underlying disease, there may be striking examples of memories that are preserved for some time even as other are lost. (psychologytoday.com)
  • Memory for skills (such as playing piano) may also persist for a relatively long time. (psychologytoday.com)
  • Fast analytic computations are optimized for a distributed, multithreaded and scalable in-memory environment for high-value, real-time decision making. (sas.com)
  • Now that you've picked out your new memory foam mattress or topper, it's time to get memory foam pillows to match. (jcpenney.com)
  • Both registers and memory cells have memory addresses, and every time a bit of data goes somewhere, it crosses a bus of some kind. (informit.com)
  • Someone who has a memory problem will be unable to remember important things for varying lengths of time. (kidshealth.org)
  • Sleep is unlikely to be the only time memories can be consolidated. (nih.gov)
  • vi If I vi a file it uses 50mb of memory the 1st time I open it. (linuxquestions.org)
  • Describe your chosen location and share a memory of your time there. (icaboston.org)
  • For the first time, an image of a memory being made at the cellular level has been captured by scientists. (livescience.com)
  • RESEARCH OBJECTIVES Background The success of common vaccines that are given in childhood, such as measles and diphtheria, as well as those used for adults, such as hepatitis B, depends on the ability of the immune system to generate and maintain immunological memory for long periods of time, sometimes throughout life. (nih.gov)
  • For each of the following time periods, comment on NTP's synthesis of the scientific evidence for learning, memory, and intelligence effects across studies and identify any information that should be added or deleted. (nih.gov)
  • The most common type is called a "fragmentary blackout" and is characterized by spotty memories for events, with "islands" of memories separated by missing periods of time in between. (nih.gov)
  • Sensory memory holds information, derived from the senses, less than one second after an item is perceived. (wikipedia.org)
  • The ability to look at an item and remember what it looked like with just a split second of observation, or memorization, is an example of sensory memory. (wikipedia.org)
  • The first precise experiments exploring this form of sensory memory were conducted by George Sperling (1963) using the "partial report paradigm. (wikipedia.org)
  • Based on these partial report experiments, Sperling was able to show that the capacity of sensory memory was approximately 12 items, but that it degraded very quickly (within a few hundred milliseconds). (wikipedia.org)
  • Iconic memory is a fast decaying store of visual information, a type of sensory memory that briefly stores an image that has been perceived for a small duration. (wikipedia.org)
  • Echoic memory is a fast decaying store of auditory information, also a sensory memory that briefly stores sounds that have been perceived for short durations. (wikipedia.org)
  • Haptic memory is a type of sensory memory that represents a database for touch stimuli. (wikipedia.org)
  • Childhood memories have several unique qualities. (wikipedia.org)
  • [1] One interpretation is that childhood memories differ from adult memories mainly in what is noticed: an adult and a child experiencing an event both notice different aspects of the event, and will have different memories of the same event. (wikipedia.org)
  • Layers of childhood memories blend with historical events to form the rich imagery of his large mixed media paintings and installations. (cdc.gov)
  • Memory encompasses the facts and experiential details that people consciously call to mind as well as ingrained knowledge that surface without effort or even awareness. (psychologytoday.com)
  • Run another memory error analysis with enhanced dangling pointer check enabled to potentially report allocation and deallocation information. (intel.com)
  • Researchers have identified two types of cells in our brains that are involved in organizing discrete memories based on when they occurred. (nih.gov)
  • Scientists still want to understand more about how our brains translate memories made on the go into long-term storage. (livescience.com)
  • Elizabeth Loftus , an experimental psychologist, has been tampering with memories in her laboratory for nearly 40 years. (slate.com)
  • The human brain regions responsible for working memory content are also used to gauge the quality, or uncertainty, of memories, a team of scientists has found. (nih.gov)
  • Researchers have discovered lion's mane mushrooms improve brain cell growth and memory in pre-clinical trials. (sciencedaily.com)
  • The researchers conducted a pair of experiments to better understand how the brain stores working memory information and how, simultaneously, the brain represents the uncertainty-or, how good the memory is-of remembered items. (nih.gov)
  • The researchers exposed the neurons to the chemical serotonin, which has been shown to stimulate memory formation (this discovery won Eric Kandel and collaborators the Nobel Prize in 2000). (livescience.com)
  • The researchers also saw that both sides of the synapse (called the pre- and post- sides) are involved in forming the memory, rather than just one, as some experts thought. (livescience.com)
  • Understanding the mechanisms by which memories in childhood are encoded and later retrieved has important implications in many areas. (wikipedia.org)
  • [1] Several hypotheses have been proposed to explain the mechanisms underpinning childhood memory. (wikipedia.org)
  • The NIH Office of Behavioral and Social Science Research presents the lecture Epigenetic mechanisms in memory formation by Dr. J. David Sweatt, University of Alabama at Birmingham. (nih.gov)
  • This presentation will address the idea that conservation of epigenetic mechanisms for information storage represents a unifying model in biology, with epigenetic mechanisms being utilized for cellular memory at levels from behavioral memory to development to cellular differentiation. (nih.gov)
  • Do epigenetic mechanisms operate in behavioral memory formation, including reward-based learning? (nih.gov)
  • What mechanisms regulate innate immune memory which impact HIV acquisition? (nih.gov)
  • Allocate a block of size bytes with alignment suitable for all memory accesses (including vectors if available on the CPU). (ffmpeg.org)
  • Allocate or reallocate a block of memory. (ffmpeg.org)
  • When an application terminates, it is the operating system's responsibility to reallocate this memory for other applications. (oreilly.com)
  • In such cases, dementia gradually grows more severe and memory worsens to a much greater extent than is typical in the general population. (psychologytoday.com)
  • Memory loss is a major part of this functional decline, typically emerging as a mild impairment and growing more severe as dementia worsens. (psychologytoday.com)
  • How severe is memory loss in dementia? (psychologytoday.com)
  • But dementia can ultimately involve severe memory problems such as being unable to retain new information or recognize loved ones. (psychologytoday.com)
  • But even these various preserved memories may be lost as dementia becomes more severe. (psychologytoday.com)
  • The more severe the illness or injury, the longer the memory loss is likely to last. (kidshealth.org)
  • With this severe form of blackout, memories of events do not form and typically cannot be recovered. (nih.gov)
  • MCI -a condition in which people have more memory problems than normal for their age-often, but not always, leads to memory loss and other signs of dementia. (nih.gov)
  • The study provides evidence that a behavioral intervention can slow memory decline in older African Americans at risk for dementia. (nih.gov)
  • How does dementia affect memory? (psychologytoday.com)
  • Consequently, memory problems are among the core symptoms of dementia. (psychologytoday.com)
  • People with dementia may quickly forget personal experiences, frequently repeat themselves , experience distorted memories, not recognize family members, or get lost in a place they once knew well, along with other forms of memory breakdown. (psychologytoday.com)
  • Is memory loss the same in all forms of dementia? (psychologytoday.com)
  • While dementia generally involves memory impairments, there are differences with regard to when that dysfunction begins. (psychologytoday.com)
  • In Alzheimer's, memory problems are often an early symptom, but in frontotemporal dementia and vascular dementia they may appear after other symptoms, such as difficulty completing complex tasks. (psychologytoday.com)
  • Our idea was to identify bioactive compounds from natural sources that could reach the brain and regulate the growth of neurons, resulting in improved memory formation," Dr Martinez-Marmol said. (sciencedaily.com)
  • Kelsey Martin, a biochemist at the University of California, Los Angeles, and colleagues investigated memory formation in neurons from the sea slug Aplysia californica , a good model for brain cells in other organisms, including humans. (livescience.com)
  • The memory for object-face pairs proved to be significantly better than for scene-face pairs. (nih.gov)
  • The memory for object-face pairs was much better than for scene-face pairs. (nih.gov)
  • And with advancing age, some decline in memory ability is typical. (psychologytoday.com)
  • AMCI is characterized by a decline in memory capacity with retention of mostly intact executive functions. (medicalnewstoday.com)
  • Finally, the function of long-term memory is to store through various categorical models or systems. (wikipedia.org)
  • The science of memory also highlights ways anyone can improve their memory , whether the goal is sharpening memory ability for the long term or just passing exams this semester. (psychologytoday.com)
  • Dec. 27, 2018 Long-term memory (LTM) is formed by repetitive training trials with rest intervals and LTM formation requires transcription factors, including CREB and c-Fos. (sciencedaily.com)
  • A study provides the first convincing evidence that caffeine enhances long-term memory in people - provided the dose is right. (newscientist.com)
  • He concludes that caffeine enhances long-term memory by improving the process of memory consolidation. (newscientist.com)
  • The results have impressed Geraldine Wright of Newcastle University, UK, who last year showed the link between caffeine and long-term memory in honeybees. (newscientist.com)
  • The image shows that proteins are created at connections between brain cells when a long-term memory is formed . (livescience.com)
  • One distinction between short-term and long-term memory is this requirement for making new proteins," said co-investigator Wayne Sossin, a neuroscientist at McGill University in Montreal. (livescience.com)
  • Although functional long-term T cell memory has been repeatedly demonstrated for both CD4 and CD8 T cells, a number of important questions regarding T cell memory remain to be answered. (nih.gov)
  • 4. Histone acetylation increases in memory formation, and histone deacetylase (HDAC) inhibitors enhance both memory formation and hippocampal long-term potentiation. (nih.gov)
  • 5. Histone subunit exchange controls long-term and remote memory stabilization for threat learning. (nih.gov)
  • Comment on whether the approach to search for and select animal studies relevant to evaluating potential long-term effects of acute sarin exposure on learning, memory and intelligence as described in the methods was objectively applied and clearly presented. (nih.gov)
  • When the tool is active, it displays data received from this library about memory events and problems that occur in the application being analyzed. (qnx.com)
  • B cell memory induction is known to occur within the germinal centers of secondary lymphoid organs. (nih.gov)
  • Declarative, or explicit, memory is the conscious storage and recollection of data. (wikipedia.org)
  • [1] The same research argues against the Freudian theory that early memories are repressed because of negative affective content. (wikipedia.org)
  • When reading, working memory allows us to store the content we just read a few seconds ago while our eyes keep scanning through the new sentences. (nih.gov)
  • Our research is the first to reveal that the neural populations that encode the content of working memory also represent the uncertainty of memory. (nih.gov)
  • In addition to supplementation, there are other ways to support memory, including exercising regularly, getting more sleep and eating a diet rich in foods containing phytonutrients that support brain health, like apples, grapes, and oranges, and beverages such as tea. (prnewswire.com)
  • Research suggests it may help support communication between brain cells by maintaining levels of important brain chemicals The Cistanche extract in NUTRILITE MEMORY BUILDER Supplement helps protect and nourish the brain by supporting optimal blood flow. (prnewswire.com)
  • It's your memory - and it's part of your complex and multitalented brain. (kidshealth.org)
  • If your brain judges the information important, it places it in your memory "files. (kidshealth.org)
  • Old information and new information, or memories, are thought to be processed and stored away in different areas of the cerebral cortex , or the "gray matter" of the brain - the largest, outermost part of the brain. (kidshealth.org)
  • At any age, an injury to the head and brain can cause trouble with somebody's memory. (kidshealth.org)
  • Abusing alcohol or using illegal drugs is another way to injure the brain and cause memory problems. (kidshealth.org)
  • Your brain is working for you when you're resting, so rest is important for memory and cognitive function," Davachi explains. (nih.gov)
  • Pre-clinical testing found the lion's mane mushroom had a significant impact on the growth of brain cells and improving memory. (sciencedaily.com)
  • This important research is unravelling the molecular mechanism of lion's mane mushroom compounds and their effects on brain function, particularly memory," Dr Lee said. (sciencedaily.com)
  • It is not only crucial for the brain to remember things, but also to weigh how good the memory is: How certain are we that a specific memory is accurate? (nih.gov)
  • While studies on human behaviors have shown that people are able to evaluate the quality of their memory, less clear is how the brain achieves this. (nih.gov)
  • More specifically, it had previously been unknown whether the brain regions that hold the memorized item also register the quality of that memory. (nih.gov)
  • Scientists believe that the brain "replays" memories, reactivating the same activity patterns as during the experience itself. (nih.gov)
  • These results suggest that these brain regions coordinate to replay recent experiences during periods of rest in order to consolidate memories. (nih.gov)
  • During a blackout, a person is still awake but their brain is not creating new memories. (nih.gov)
  • However, I am currently encountering serious memory leaks as described below. (google.com)
  • The memory leaks happened when I use NSOperationQueue with ASIHTTPRequest to download a website and its linked html files. (google.com)
  • 1. All experiments experienced memory leaks. (google.com)
  • 4. Only experiment 3 for site C showed steady memory leaks. (google.com)
  • If you use a tool to detect memory leaks or similar problems, then deallocating memory will clean up the output of such tools. (oreilly.com)
  • Devuelve el máximo de memoria, en bytes, que se ha asignado a su script PHP. (php.net)
  • Devuelve el máximo de memoria en bytes. (php.net)
  • Unconscious influences of memory were found to alter the subjective experiences of participants. (wikipedia.org)
  • Professional assessment can help determine whether an individual's mild memory loss is a function of normal aging or a sign of a serious condition. (psychologytoday.com)
  • Relatively mild memory symptoms may include not remembering that one completed a task or recently told someone something. (psychologytoday.com)
  • The deallocation makes the access to the offending memory address logically invalid. (intel.com)
  • Thus, when a program allocates and then frees up memory, the deallocation of memory is not normally reflected in the application's memory usage as seen from the operating system perspective. (oreilly.com)
  • Subjective cognitive decline (SCD) is defined as self-reported memory problems that have been getting worse over the past year. (cdc.gov)
  • Although memory loss can be considered a natural part of the aging process, it is a major contributor to mild cognitive decline, and it is listed as one of the greatest fears among individuals older than 65 years of age. (medscape.com)
  • As with many health concerns, ethnic groups experience memory loss and cognitive decline differently. (medscape.com)
  • A review of current research on memory loss and culture, social determinants, and ethnicity confirms existing knowledge about negative correlations between socioeconomic status, education level, mental activity, and memory loss and reveals few conclusive correlations between health risk factors and memory loss or cognitive decline. (medscape.com)
  • This fourth essay on "Nutrition, Culture, and Women's Health" describes some of the ethnic differences related to memory loss and cognitive decline. (medscape.com)
  • The result is tens of thousands of people are reporting signs that their memory is getting worse. (cdc.gov)
  • [9] This study shows that people are even implicitly making connections amongst their memories. (wikipedia.org)
  • Though memory naturally declines with age, many people are able to stay mentally sharp. (psychologytoday.com)
  • Through committed practice with memory-enhancing techniques, some people train themselves to remember amazing quantities of information, such as lengthy sequences of words or digits. (psychologytoday.com)
  • People with MCI may experience memory problems that are noticeable to themselves or others while still maintaining normal daily function. (psychologytoday.com)
  • Computers use many different microchips and processors, with perhaps the most familiar being the CPU and the main memory what people commonly refer to as the computer's RAM. (informit.com)
  • Strokes , which also affect older people, are another medical problem that can affect someone's memory. (kidshealth.org)
  • A fast, in-memory analytical programming language allows multiple users to analyze big data simultaneously and interactively. (sas.com)
  • Freescale Semiconductor , a Motorola spinoff, released today the first commercial semiconductor memory that uses magnetic properties to store data. (technologyreview.com)
  • This new type of chip will compete with other established forms of semiconductor memory, such as Flash and random-access memory (RAM). (technologyreview.com)
  • Freescale Semiconductor has developed a new type of semiconductor memory, called magnetoresistive random-access memory (MRAM), that uses the magnetic properties of electrons to store information. (technologyreview.com)
  • The fundamental feature that makes MRAM an alluring alternative to other forms of semiconductor memory is the way it stores data. (technologyreview.com)
  • Memory is a semiconductor device that is used as data storage device on an integrated circuit . (digikey.com)
  • Memory is the faculty of the mind by which data or information is encoded, stored, and retrieved when needed. (wikipedia.org)
  • Total memory available to hold data. (mathworks.com)
  • In-memory analytics and interactive, analytical data preparation, exploration, modeling and deployment deliver precise answers instantly. (sas.com)
  • Our in-memory infrastructure eliminates costly data movement and persists data in memory for the entire analytic session. (sas.com)
  • Data is held in memory to boost speed and reduce latency. (sas.com)
  • After it's dealt with these data bits to its satisfaction, the CPU works together with a memory controller to move the results out to memory cells (storage places on a memory chip). (informit.com)
  • However, we may need to be concerned with issues such as how we handle sensitive data and whether we need to even worry about freeing memory if the application is about to terminate. (oreilly.com)
  • It is a good idea to overwrite sensitive data in memory once it is no longer needed. (oreilly.com)
  • It should be noted that for many operating systems, certified to handle classified data, memory is automatically cleared when the program is no longer using it. (oreilly.com)
  • Moving data via samba If I move data to and from the file server via Samba / explorer all of the systems memory is used, this is not dropped off after the move has completed. (linuxquestions.org)
  • The only way the memory usage drops off is if the data is deleted from the fileserver. (linuxquestions.org)
  • Because this form of memory degrades so quickly, participants would see the display but be unable to report all of the items (12 in the "whole report" procedure) before they decayed. (wikipedia.org)
  • That's because the process of consolidation is likely to begin as soon as new memories form. (newscientist.com)
  • But when the scientists induced the cells to form memories, they saw new green proteins appear under the microscope. (livescience.com)
  • Since synapses are connections between cells, experts think that fortifying these connections, or perhaps even making new ones, helps our minds associate different ideas and form memories of connected events. (livescience.com)
  • Antigen persistence, in the form of immune complexes concentrated on follicular dendritic cells within germinal centers, is thought to be important for the persistence of B cell memory. (nih.gov)
  • Maximum possible array: 60021 MB (6.294e+10 bytes) * Memory available for all arrays: 60021 MB (6.294e+10 bytes) * Memory used by MATLAB: 3337 MB (3.499e+09 bytes) Physical Memory (RAM): 65189 MB (6.836e+10 bytes) * Limited by System Memory (physical + swap file) available. (mathworks.com)
  • Size in bytes for the memory block to be allocated. (ffmpeg.org)
  • John Davies shows a Spring work-flow consuming 7.4kB XML messages, binding them to 25kB Java but storing them in just 450 bytes each, 10 million derivative contracts in-memory on a laptop. (infoq.com)
  • Memory is the process of storing and then remembering this information. (medlineplus.gov)
  • Use the structure to display the amount of memory reserved for the MATLAB process. (mathworks.com)
  • Total system memory reserved for the MATLAB process. (mathworks.com)
  • field is the amount of available virtual memory for the MATLAB process. (mathworks.com)
  • then there is insufficient system memory to allow for the mapping of all virtual addresses in the largest available block of the MATLAB process. (mathworks.com)
  • The experiment also revealed some surprising aspects of memory formation, which remains a somewhat mysterious process. (livescience.com)
  • Right now we are only able to allocate a max of 2GB of memory to a single AFNI process, but it is our understanding that this may be operating system-imposed. (nih.gov)
  • To examine the effects of supervised high versus low soya diets on attention, memory and frontal lobe function in young healthy adults of both sexes. (researchgate.net)
  • While most memory-supporting supplements contain Ginkgo biloba, NUTRILITE MEMORY BUILDER contains a unique and complementary combination of standardized extracts of Ginkgo biloba and the herb Cistanche tubulosa. (prnewswire.com)
  • Immunity that protects the individual against subsequent exposure to the pathogen depends upon the generation of memory T and B cells during initial exposure. (nih.gov)
  • One controversial, but very important, issue is whether T cell memory, like B cell memory, depends on antigen persistence. (nih.gov)
  • Memory lymphocytes must then persist in sufficient numbers, and be readily induced to efficiently eliminate the pathogen upon re-exposure in order to prevent disease. (nih.gov)
  • Does HIV exposure or infection induce innate immune memory? (nih.gov)
  • Both groups had memory decline, measured by performance on a standard memory test, but the behavioral-activation group declined by just 1.2 percent, compared with 9.3 percent for the control group. (nih.gov)