The age of the mother in PREGNANCY.
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Age of the biological father.
A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)
The sequence in which children are born into the family.
Pregnancy in which the mother and/or FETUS are at greater than normal risk of MORBIDITY or MORTALITY. Causes include inadequate PRENATAL CARE, previous obstetrical history (ABORTION, SPONTANEOUS), pre-existing maternal disease, pregnancy-induced disease (GESTATIONAL HYPERTENSION), and MULTIPLE PREGNANCY, as well as advanced maternal age above 35.
An infant during the first month after birth.
Percutaneous transabdominal puncture of the uterus during pregnancy to obtain amniotic fluid. It is commonly used for fetal karyotype determination in order to diagnose abnormal fetal conditions.
The number of offspring a female has borne. It is contrasted with GRAVIDITY, which refers to the number of pregnancies, regardless of outcome.
Results of conception and ensuing pregnancy, including LIVE BIRTH; STILLBIRTH; SPONTANEOUS ABORTION; INDUCED ABORTION. The outcome may follow natural or artificial insemination or any of the various ASSISTED REPRODUCTIVE TECHNIQUES, such as EMBRYO TRANSFER or FERTILIZATION IN VITRO.
The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds or kilograms.
The age of the conceptus, beginning from the time of FERTILIZATION. In clinical obstetrics, the gestational age is often estimated as the time from the last day of the last MENSTRUATION which is about 2 weeks before OVULATION and fertilization.
Determination of the nature of a pathological condition or disease in the postimplantation EMBRYO; FETUS; or pregnant female before birth.
The possession of a third chromosome of any one type in an otherwise diploid cell.
The beginning third of a human PREGNANCY, from the first day of the last normal menstrual period (MENSTRUATION) through the completion of 14 weeks (98 days) of gestation.
Conditions or pathological processes associated with pregnancy. They can occur during or after pregnancy, and range from minor discomforts to serious diseases that require medical interventions. They include diseases in pregnant females, and pregnancies in females with diseases.
Malformations of organs or body parts during development in utero.
The failure of homologous CHROMOSOMES or CHROMATIDS to segregate during MITOSIS or MEIOSIS with the result that one daughter cell has both of a pair of parental chromosomes or chromatids and the other has none.
Expulsion of the product of FERTILIZATION before completing the term of GESTATION and without deliberate interference.
Official certifications by a physician recording the individual's birth date, place of birth, parentage and other required identifying data which are filed with the local registrar of vital statistics.
In utero measurement corresponding to the sitting height (crown to rump) of the fetus. Length is considered a more accurate criterion of the age of the fetus than is the weight. The average crown-rump length of the fetus at term is 36 cm. (From Williams Obstetrics, 18th ed, p91)
A prenatal ultrasonography measurement of the soft tissue behind the fetal neck. Either the translucent area below the skin in the back of the fetal neck (nuchal translucency) or the distance between occipital bone to the outer skin line (nuchal fold) is measured.
The chromosomal constitution of cells which deviate from the normal by the addition or subtraction of CHROMOSOMES, chromosome pairs, or chromosome fragments. In a normally diploid cell (DIPLOIDY) the loss of a chromosome pair is termed nullisomy (symbol: 2N-2), the loss of a single chromosome is MONOSOMY (symbol: 2N-1), the addition of a chromosome pair is tetrasomy (symbol: 2N+2), the addition of a single chromosome is TRISOMY (symbol: 2N+1).
Clinical conditions caused by an abnormal chromosome constitution in which there is extra or missing chromosome material (either a whole chromosome or a chromosome segment). (from Thompson et al., Genetics in Medicine, 5th ed, p429)
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Extraction of the FETUS by means of abdominal HYSTEROTOMY.
The middle third of a human PREGNANCY, from the beginning of the 15th through the 28th completed week (99 to 196 days) of gestation.
An infant having a birth weight of 2500 gm. (5.5 lb.) or less but INFANT, VERY LOW BIRTH WEIGHT is available for infants having a birth weight of 1500 grams (3.3 lb.) or less.
The visualization of tissues during pregnancy through recording of the echoes of ultrasonic waves directed into the body. The procedure may be applied with reference to the mother or the fetus and with reference to organs or the detection of maternal or fetal disease.
Postnatal deaths from BIRTH to 365 days after birth in a given population. Postneonatal mortality represents deaths between 28 days and 365 days after birth (as defined by National Center for Health Statistics). Neonatal mortality represents deaths from birth to 27 days after birth.
The beta subunit of human CHORIONIC GONADOTROPIN. Its structure is similar to the beta subunit of LUTEINIZING HORMONE, except for the additional 30 amino acids at the carboxy end with the associated carbohydrate residues. HCG-beta is used as a diagnostic marker for early detection of pregnancy, spontaneous abortion (ABORTION, SPONTANEOUS); ECTOPIC PREGNANCY; HYDATIDIFORM MOLE; CHORIOCARCINOMA; or DOWN SYNDROME.
The condition of carrying two or more FETUSES simultaneously.
Death of the developing young in utero. BIRTH of a dead FETUS is STILLBIRTH.
CHILDBIRTH before 37 weeks of PREGNANCY (259 days from the first day of the mother's last menstrual period, or 245 days after FERTILIZATION).
Female parents, human or animal.
A product of the PLACENTA, and DECIDUA, secreted into the maternal circulation during PREGNANCY. It has been identified as an IGF binding protein (IGFBP)-4 protease that proteolyzes IGFBP-4 and thus increases IGF bioavailability. It is found also in human FIBROBLASTS, ovarian FOLLICULAR FLUID, and GRANULOSA CELLS. The enzyme is a heterotetramer of about 500-kDa.
A HERNIA due to an imperfect closure or weakness of the umbilical ring. It appears as a skin-covered protrusion at the UMBILICUS during crying, coughing, or straining. The hernia generally consists of OMENTUM or SMALL INTESTINE. The vast majority of umbilical hernias are congenital but can be acquired due to severe abdominal distention.
A congenital defect with major fissure in the ABDOMINAL WALL lateral to, but not at, the UMBILICUS. This results in the extrusion of VISCERA. Unlike OMPHALOCELE, herniated structures in gastroschisis are not covered by a sac or PERITONEUM.
Determination of the nature of a pathological condition or disease in the OVUM; ZYGOTE; or BLASTOCYST prior to implantation. CYTOGENETIC ANALYSIS is performed to determine the presence or absence of genetic disease.
Care provided the pregnant woman in order to prevent complications, and decrease the incidence of maternal and prenatal mortality.
An assisted reproductive technique that includes the direct handling and manipulation of oocytes and sperm to achieve fertilization in vitro.
The event that a FETUS is born alive with heartbeats or RESPIRATION regardless of GESTATIONAL AGE. Such liveborn is called a newborn infant (INFANT, NEWBORN).
The event that a FETUS is born dead or stillborn.
Deaths occurring from the 28th week of GESTATION to the 28th day after birth in a given population.
The lengths of intervals between births to women in the population.
Clinical and laboratory techniques used to enhance fertility in humans and animals.
An infant having a birth weight lower than expected for its gestational age.
Pathophysiological conditions of the FETUS in the UTERUS. Some fetal diseases may be treated with FETAL THERAPIES.
Abortion performed because of possible fetal defects.
Pregnancy in human adolescent females under the age of 19.
Abnormal number or structure of chromosomes. Chromosome aberrations may result in CHROMOSOME DISORDERS.
Minute cells produced during development of an OOCYTE as it undergoes MEIOSIS. A polar body contains one of the nuclei derived from the first or second meiotic CELL DIVISION. Polar bodies have practically no CYTOPLASM. They are eventually discarded by the oocyte. (from King & Stansfield, A Dictionary of Genetics, 4th ed)
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Delivery of the FETUS and PLACENTA under the care of an obstetrician or a health worker. Obstetric deliveries may involve physical, psychological, medical, or surgical interventions.
The number of births in a given population per year or other unit of time.
A specific pair of GROUP G CHROMOSOMES of the human chromosome classification.
A method for diagnosis of fetal diseases by sampling the cells of the placental chorionic villi for DNA analysis, presence of bacteria, concentration of metabolites, etc. The advantage over amniocentesis is that the procedure can be carried out in the first trimester.
Medical problems associated with OBSTETRIC LABOR, such as BREECH PRESENTATION; PREMATURE OBSTETRIC LABOR; HEMORRHAGE; or others. These complications can affect the well-being of the mother, the FETUS, or both.
Two individuals derived from two FETUSES that were fertilized at or about the same time, developed in the UTERUS simultaneously, and born to the same mother. Twins are either monozygotic (TWINS, MONOZYGOTIC) or dizygotic (TWINS, DIZYGOTIC).
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
A specific pair of GROUP E CHROMOSOMES of the human chromosome classification.
The short, acrocentric human chromosomes, called group G in the human chromosome classification. This group consists of chromosome pairs 21 and 22 and the Y chromosome.
A demographic parameter indicating a person's status with respect to marriage, divorce, widowhood, singleness, etc.
Mapping of the KARYOTYPE of a cell.
The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.
The part of a human or animal body connecting the HEAD to the rest of the body.
The consequences of exposing the FETUS in utero to certain factors, such as NUTRITION PHYSIOLOGICAL PHENOMENA; PHYSIOLOGICAL STRESS; DRUGS; RADIATION; and other physical or chemical factors. These consequences are observed later in the offspring after BIRTH.
Change of heartbeat induced by pressure on the eyeball, manipulation of extraocular muscles, or pressure upon the tissue remaining in the orbital apex after enucleation.
Social and economic factors that characterize the individual or group within the social structure.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
The number of males per 100 females.
The nursing of an infant at the breast.
A specific pair of GROUP D CHROMOSOMES of the human chromosome classification.
Exposure of the female parent, human or animal, to potentially harmful chemical, physical, or biological agents in the environment or to environmental factors that may include ionizing radiation, pathogenic organisms, or toxic chemicals that may affect offspring. It includes pre-conception maternal exposure.
Onset of OBSTETRIC LABOR before term (TERM BIRTH) but usually after the FETUS has become viable. In humans, it occurs sometime during the 29th through 38th week of PREGNANCY. TOCOLYSIS inhibits premature labor and can prevent the BIRTH of premature infants (INFANT, PREMATURE).
A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.
An assisted fertilization technique consisting of the microinjection of a single viable sperm into an extracted ovum. It is used principally to overcome low sperm count, low sperm motility, inability of sperm to penetrate the egg, or other conditions related to male infertility (INFERTILITY, MALE).
Either one of the two small elongated rectangular bones that together form the bridge of the nose.
Diabetes mellitus induced by PREGNANCY but resolved at the end of pregnancy. It does not include previously diagnosed diabetics who become pregnant (PREGNANCY IN DIABETICS). Gestational diabetes usually develops in late pregnancy when insulin antagonistic hormones peaks leading to INSULIN RESISTANCE; GLUCOSE INTOLERANCE; and HYPERGLYCEMIA.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Educational attainment or level of education of individuals.
The transfer of mammalian embryos from an in vivo or in vitro environment to a suitable host to improve pregnancy or gestational outcome in human or animal. In human fertility treatment programs, preimplantation embryos ranging from the 4-cell stage to the blastocyst stage are transferred to the uterine cavity between 3-5 days after FERTILIZATION IN VITRO.
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome.
Three or more consecutive spontaneous abortions.
The number of pregnancies, complete or incomplete, experienced by a female. It is different from PARITY, which is the number of offspring borne. (From Stedman, 26th ed)
I'm sorry for any confusion, but the term "Norway" is a country name and doesn't have a medical definition. If you have any medical or health-related questions, I'd be happy to help!
A condition of fetal overgrowth leading to a large-for-gestational-age FETUS. It is defined as BIRTH WEIGHT greater than 4,000 grams or above the 90th percentile for population and sex-specific growth curves. It is commonly seen in GESTATIONAL DIABETES; PROLONGED PREGNANCY; and pregnancies complicated by pre-existing diabetes mellitus.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
I'm sorry for any confusion, but "Sicily" is not a medical term that has a definition in the field of medicine. Sicily is actually the largest island in the Mediterranean Sea and it is located off the southern coast of Italy. If you have any questions related to medical terminology or health-related topics, I would be happy to help!
The last third of a human PREGNANCY, from the beginning of the 29th through the 42nd completed week (197 to 294 days) of gestation.
The condition of carrying TWINS simultaneously.
The offspring in multiple pregnancies (PREGNANCY, MULTIPLE): TWINS; TRIPLETS; QUADRUPLETS; QUINTUPLETS; etc.
A stratum of people with similar position and prestige; includes social stratification. Social class is measured by criteria such as education, occupation, and income.
A condition in pregnant women with elevated systolic (>140 mm Hg) and diastolic (>90 mm Hg) blood pressure on at least two occasions 6 h apart. HYPERTENSION complicates 8-10% of all pregnancies, generally after 20 weeks of gestation. Gestational hypertension can be divided into several broad categories according to the complexity and associated symptoms, such as EDEMA; PROTEINURIA; SEIZURES; abnormalities in BLOOD COAGULATION and liver functions.
I'm sorry for any confusion, but "Denmark" is not a medical term and does not have a medical definition. It is a country located in northern Europe. If you have any questions related to medicine or health, I would be happy to try to help answer them.
The failure of a FETUS to attain its expected FETAL GROWTH at any GESTATIONAL AGE.
A hydroxylated metabolite of ESTRADIOL or ESTRONE that has a hydroxyl group at C3, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During PREGNANCY, a large amount of estriol is produced by the PLACENTA. Isomers with inversion of the hydroxyl group or groups are called epiestriol.
A type of CELL NUCLEUS division, occurring during maturation of the GERM CELLS. Two successive cell nucleus divisions following a single chromosome duplication (S PHASE) result in daughter cells with half the number of CHROMOSOMES as the parent cells.
The care of women and a fetus or newborn given before, during, and after delivery from the 28th week of gestation through the 7th day after delivery.
A method, developed by Dr. Virginia Apgar, to evaluate a newborn's adjustment to extrauterine life. Five items - heart rate, respiratory effort, muscle tone, reflex irritability, and color - are evaluated 60 seconds after birth and again five minutes later on a scale from 0-2, 0 being the lowest, 2 being normal. The five numbers are added for the Apgar score. A score of 0-3 represents severe distress, 4-7 indicates moderate distress, and a score of 7-10 predicts an absence of difficulty in adjusting to extrauterine life.
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
Inability to reproduce after a specified period of unprotected intercourse. Reproductive sterility is permanent infertility.
Intentional removal of a fetus from the uterus by any of a number of techniques. (POPLINE, 1978)
Separase is a caspase-like cysteine protease, which plays a central role in triggering ANAPHASE by cleaving the SCC1/RAD21 subunit of the cohesin complex. Cohesin holds the sister CHROMATIDS together during METAPHASE and its cleavage results in chromosome segregation.
Three individuals derived from three FETUSES that were fertilized at or about the same time, developed in the UTERUS simultaneously, and born to the same mother.
Human females who are pregnant, as cultural, psychological, or sociological entities.
The process of giving birth to one or more offspring.
Artificially induced UTERINE CONTRACTION. Generally, LABOR, OBSTETRIC is induced with the intent to cause delivery of the fetus and termination of pregnancy.
A human infant born before 37 weeks of GESTATION.
Inhaling and exhaling the smoke of burning TOBACCO.
The capacity to conceive or to induce conception. It may refer to either the male or female.
I'm sorry for any confusion, but "Sweden" is not a medical term and does not have a medical definition. It is a country located in Northern Europe. If you have any questions related to medical topics or definitions, I would be happy to try to help answer them!
**I'm really sorry, but I can't fulfill your request.**
The pH in solutions of proteins and related compounds at which the dipolar ions are at a maximum.
A malformation of the nervous system caused by failure of the anterior neuropore to close. Infants are born with intact spinal cords, cerebellums, and brainstems, but lack formation of neural structures above this level. The skull is only partially formed but the eyes are usually normal. This condition may be associated with folate deficiency. Affected infants are only capable of primitive (brain stem) reflexes and usually do not survive for more than two weeks. (From Menkes, Textbook of Child Neurology, 5th ed, p247)
Abnormal number or structure of the SEX CHROMOSOMES. Some sex chromosome aberrations are associated with SEX CHROMOSOME DISORDERS and SEX CHROMOSOME DISORDERS OF SEX DEVELOPMENT.
The heart rate of the FETUS. The normal range at term is between 120 and 160 beats per minute.
The state of PREGNANCY in women with DIABETES MELLITUS. This does not include either symptomatic diabetes or GLUCOSE INTOLERANCE induced by pregnancy (DIABETES, GESTATIONAL) which resolves at the end of pregnancy.
Size and composition of the family.
Maternal deaths resulting from complications of pregnancy and childbirth in a given population.
The occurrence in an individual of two or more cell populations of different chromosomal constitutions, derived from a single ZYGOTE, as opposed to CHIMERISM in which the different cell populations are derived from more than one zygote.
Number of fetal deaths with stated or presumed gestation of 20 weeks or more in a given population. Late fetal mortality is death after of 28 weeks or more.
Organized efforts by communities or organizations to improve the health and well-being of infants.
The medium-sized, acrocentric human chromosomes, called group D in the human chromosome classification. This group consists of chromosome pairs 13, 14, and 15.
Female germ cells derived from OOGONIA and termed OOCYTES when they enter MEIOSIS. The primary oocytes begin meiosis but are arrested at the diplotene state until OVULATION at PUBERTY to give rise to haploid secondary oocytes or ova (OVUM).
Organized efforts by communities or organizations to improve the health and well-being of the mother.
Individuals whose ancestral origins are in the continent of Europe.
Diminished or absent ability of a female to achieve conception.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
CHILDBIRTH at the end of a normal duration of PREGNANCY, between 37 to 40 weeks of gestation or about 280 days from the first day of the mother's last menstrual period.
The behavior patterns associated with or characteristic of a mother.
I'm sorry for any confusion, but 'England' is not a medical term and does not have a medical definition. England is a country that is part of the United Kingdom, known for its rich history, cultural heritage, and contributions to medical science. However, in a medical context, it may refer to the location of a patient, healthcare provider, or research study, but it is not a term with a specific medical meaning.
I'm sorry for any confusion, but "Nepal" is not a medical term that has a definition in the field of medicine. It is actually the name of a country located in South Asia, known officially as the Federal Democratic Republic of Nepal. If you have any questions related to medicine or health, I would be happy to try and help answer those for you!
The state of birth outside of wedlock. It may refer to the offspring or the parents.
Children who have reached maturity or the legal age of majority.
Extraction of the fetus by means of obstetrical instruments.
The distance from the sole to the crown of the head with body standing on a flat surface and fully extended.
The unborn young of a viviparous mammal, in the postembryonic period, after the major structures have been outlined. In humans, the unborn young from the end of the eighth week after CONCEPTION until BIRTH, as distinguished from the earlier EMBRYO, MAMMALIAN.
Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
Morphological and physiological development of FETUSES.
An important aggregate factor in epidemiological studies of women's health. The concept usually includes the number and timing of pregnancies and their outcomes, the incidence of breast feeding, and may include age of menarche and menopause, regularity of menstruation, fertility, gynecological or obstetric problems, or contraceptive usage.
Two offspring from the same PREGNANCY. They are from two OVA, fertilized at about the same time by two SPERMATOZOA. Such twins are genetically distinct and can be of different sexes.
I'm sorry for any confusion, but "Wales" is not a medical term and does not have a medical definition. It is a country that is part of the United Kingdom, located in Europe. If you have any questions about a specific medical topic, I would be happy to help answer those!
Male parents, human or animal.
Persons or animals having at least one parent in common. (American College Dictionary, 3d ed)
The ratio of the number of conceptions (CONCEPTION) including LIVE BIRTH; STILLBIRTH; and fetal losses, to the mean number of females of reproductive age in a population during a set time period.
Groups of individuals whose putative ancestry is from native continental populations based on similarities in physical appearance.
Abnormal placentation in which the PLACENTA implants in the lower segment of the UTERUS (the zone of dilation) and may cover part or all of the opening of the CERVIX. It is often associated with serious antepartum bleeding and PREMATURE LABOR.
The term "United States" in a medical context often refers to the country where a patient or study participant resides, and is not a medical term per se, but relevant for epidemiological studies, healthcare policies, and understanding differences in disease prevalence, treatment patterns, and health outcomes across various geographic locations.
The co-occurrence of pregnancy and an INFECTION. The infection may precede or follow FERTILIZATION.
In females, the period that is shortly after giving birth (PARTURITION).
I'm sorry for any confusion, but "Brazil" is not a medical term or concept, it is a country located in South America, known officially as the Federative Republic of Brazil. If you have any questions related to health, medicine, or science, I'd be happy to help answer those!
Detection of a MUTATION; GENOTYPE; KARYOTYPE; or specific ALLELES associated with genetic traits, heritable diseases, or predisposition to a disease, or that may lead to the disease in descendants. It includes prenatal genetic testing.
The first alpha-globulins to appear in mammalian sera during FETAL DEVELOPMENT and the dominant serum proteins in early embryonic life.
Individuals whose ancestral origins are in the continent of Africa.
A range of values for a variable of interest, e.g., a rate, constructed so that this range has a specified probability of including the true value of the variable.
An indicator of body density as determined by the relationship of BODY WEIGHT to BODY HEIGHT. BMI=weight (kg)/height squared (m2). BMI correlates with body fat (ADIPOSE TISSUE). Their relationship varies with age and gender. For adults, BMI falls into these categories: below 18.5 (underweight); 18.5-24.9 (normal); 25.0-29.9 (overweight); 30.0 and above (obese). (National Center for Health Statistics, Centers for Disease Control and Prevention)

Effect of the interval between pregnancies on perinatal outcomes. (1/2227)

BACKGROUND: A short interval between pregnancies has been associated with adverse perinatal outcomes. Whether that association is due to confounding by other risk factors, such as maternal age, socioeconomic status, and reproductive history, is unknown. METHODS: We evaluated the interpregnancy interval in relation to low birth weight, preterm birth, and small size for gestational age by analyzing data from the birth certificates of 173,205 singleton infants born alive to multiparous mothers in Utah from 1989 to 1996. RESULTS: Infants conceived 18 to 23 months after a previous live birth had the lowest risks of adverse perinatal outcomes; shorter and longer interpregnancy intervals were associated with higher risks. These associations persisted when the data were stratified according to and controlled for 16 biologic, sociodemographic, and behavioral risk factors. As compared with infants conceived 18 to 23 months after a live birth, infants conceived less than 6 months after a live birth had odds ratios of 1.4 (95 percent confidence interval, 1.3 to 1.6) for low birth weight, 1.4 (95 percent confidence interval, 1.3 to 1.5) for preterm birth, and 1.3 (95 percent confidence interval, 1.2 to 1.4) for small size for gestational age; infants conceived 120 months or more after a live birth had odds ratios of 2.0 (95 percent confidence interval, 1.7 to 2.4);1.5 (95 percent confidence interval, 1.3 to 1.7), and 1.8 (95 percent confidence interval, 1.6 to 2.0) for these three adverse outcomes, respectively, when we controlled for all 16 risk factors with logistic regression. CONCLUSIONS: The optimal interpregnancy interval for preventing adverse perinatal outcomes is 18 to 23 months.  (+info)

Maternal smoking and Down syndrome: the confounding effect of maternal age. (2/2227)

Inconsistent results have been reported from studies evaluating the association of maternal smoking with birth of a Down syndrome child. Control of known risk factors, particularly maternal age, has also varied across studies. By using a population-based case-control design (775 Down syndrome cases and 7,750 normal controls) and Washington State birth record data for 1984-1994, the authors examined this hypothesized association and found a crude odds ratio of 0.80 (95% confidence interval 0.65-0.98). Controlling for broad categories of maternal age (<35 years, > or =35 years), as described in prior studies, resulted in a negative association (odds ratio = 0.87, 95% confidence interval 0.71-1.07). However, controlling for exact year of maternal age in conjunction with race and parity resulted in no association (odds ratio = 1.00, 95% confidence interval 0.82-1.24). In this study, the prevalence of Down syndrome births increased with increasing maternal age, whereas among controls the reported prevalence of smoking during pregnancy decreased with increasing maternal age. There is a substantial potential for residual confounding by maternal age in studies of maternal smoking and Down syndrome. After adequately controlling for maternal age in this study, the authors found no clear relation between maternal smoking and the risk of Down syndrome.  (+info)

Energy intake, not energy output, is a determinant of body size in infants. (3/2227)

BACKGROUND: It has been proposed that the primary determinants of body weight at 1 y of age are genetic background, as represented by parental obesity, and low total energy expenditure. OBJECTIVE: The objective was to determine the relative contributions of genetic background and energy intake and expenditure as determinants of body weight at 1 y of age. DESIGN: Forty infants of obese and 38 infants of lean mothers, half boys and half girls, were assessed at 3 mo of age for 10 risk factors for obesity: sex, risk group (obese or nonobese mothers), maternal and paternal body mass index, body weight, feeding mode (breast, bottle, or both), 3-d energy intake, nutritive sucking behavior during a test meal, total energy expenditure, sleeping energy expenditure, and interactions among them. RESULTS: The only difference between risk groups at baseline was that the high-risk group sucked more vigorously during the test meal. Four measures accounted for 62% of the variability in weight at 12 mo: 3-mo weight (41%, P = 0.0001), nutritive sucking behavior (9%, P = 0.0002), 3-d food intake (8%, P = 0.0002), and male sex (3%, P = 0.05). Food intake and sucking behavior at 3 mo accounted for similar amounts of variability in weight-for-length, body fat, fat-free mass, and skinfold thickness at 12 mo. Contrary to expectations, neither total nor sleeping energy expenditure at 3 mo nor maternal obesity contributed to measures of body size at 12 mo. CONCLUSIONS: Energy intake contributes significantly to measures of body weight and composition at 1 y of age; parental obesity and energy expenditure do not.  (+info)

Breast cancer risk in monozygotic and dizygotic female twins: a 20-year population-based cohort study in Finland from 1976 to 1995. (4/2227)

This population-based study investigated the occurrence of breast cancer over a 20-year period in a cohort of monozygotic (MZ) and dizygotic (DZ) twins in Finland. Altogether, 13,176 female twins of known zygosity who were living in Finland at the end of 1975 were identified from the Finnish Twin Cohort Study and followed-up for cancer through the Finnish Cancer Registry for the years 1976-1995. Standardized incidence ratios (SIRs) were calculated, based on national cancer incidence rates. The relative risk of breast cancer for MZ twins compared to DZ twins was decreased [SIR(MZ)/SIR(DZ) ratio = 0.78; 95% confidence interval (CI), 0.58-1.0]; the decreased risk for MZ twins (SIR = 0.76; 95% CI, 0.58-1.0) accounted for this result, whereas the risk for DZ twins did not differ from the general population risk (SIR = 0.98; 95% CI, 0.84-1.1). There was no risk decrease among MZ twins in other cancers related to reproductive behavior; i.e., number of children and age at first birth seem not to explain the decreased risk of breast cancer. Our results, which are in line with earlier studies on the same topic, suggest that prenatal influences or postnatal behavioral factors may protect MZ female twins from breast cancer.  (+info)

A family study of coarctation of the aorta. (5/2227)

Families of 100 patients with coarctation of the aorta and 50 controls for age, sex, and social status were studied to assess the influence of genetic and environmental variables in the aetiology. A tendency to familial aggregation of the condition and other congenital heart defects compatible with multifactorial inheritance was discerned. Recurrence risk for sibs is approximately 1 in 200 for coarctation of the aorta, and 1% for any form of congenital heart defect. The heritability of coarctation is estimated at 58%. The tendency for other non-cardiac defects to occur in the patients with coarctation does not appear in their sibs and is not so pronounced as in some other congenital heart conditions. Of the several environmental variables examined, there was no definitive association with any other than season of birth, which implies a possible association with maternal infection; there is also a suggestion of a paternal age effect, but these require investigation in a prospective survey.  (+info)

Fertility patterns after appendicectomy: historical cohort study. (6/2227)

OBJECTIVE: To examine fertility patterns in women who had their appendix removed in childhood. DESIGN: Historical cohort study with computerised data and fertility data for this cohort and for an age matched cohort of women from the Swedish general population. The cohorts were followed to 1994. SETTING: General population. PARTICIPANTS: 9840 women who were under 15 years when they underwent appendicectomy between 1964 and 1983; 47 590 control women. MAIN OUTCOME MEASURES: Diagnoses at discharge. Distributions of age at birth of first child among women with perforated and non-perforated appendix and women who underwent appendicectomy but were found to have a normal appendix compared with control women by using survival analysis methods. Parity distributions at the latest update of the registry were also examined. RESULTS: Women with a history of perforated appendix had a similar rate of first birth as the control women (adjusted hazard ratio 0.95; 95% confidence interval 0.88 to 1. 04) and had a similar distribution of parity at the end of follow up. Women who had had a normal appendix removed had an increased rate of first births (1.48; 1.42 to 1.54) and on average had their first child at an earlier age and reached a higher parity than control women. CONCLUSION: A history of perforated appendix in childhood does not seem to have long term negative consequences on female fertility. This may have important implications for the management of young women with suspected appendicitis as the liberal attitude to surgical explorations with a subsequently high rate of removal of a normal appendix is often justified by a perceived increased risk of infertility after perforation. Women whose appendix was found to be normal at appendicectomy in childhood seem to belong to a subgroup with a higher fertility than the general population.  (+info)

Maternal age- and gestation-specific risk for trisomy 21. (7/2227)

OBJECTIVE: To provide estimates of maternal age- and gestational age-related risks for trisomy 21. METHODS: The prevalence of trisomy 21 was examined in 57,614 women who had fetal karyotyping at 9-16 weeks of gestation for the sole indication of maternal age of 35 years or more. On the basis of the maternal age distribution and the reported maternal age-related risk for trisomy 21 at birth, the expected number of trisomy 21 cases was calculated for each gestational age subgroup (9-10 weeks, 11-14 weeks and 15-16 weeks). The ratio of the observed to expected number of cases of trisomy 21 was then calculated and regression analysis was applied to derive a smoothened curve. The formula for maternal age- and gestational age-related risk was then applied to a population of 96,127 pregnancies that were examined at 10-14 weeks to calculate the expected number of trisomy 21 pregnancies, and this number was compared to the observed number of 326. RESULTS: In the 57,614 pregnancies there were 538 cases of trisomy 21. The relative prevalences of trisomy 21, compared to a prevalence of 1.0 at 40 weeks, was 10 exp(0.2718 x log(10)(gestation)2 - 1.023 x log10(gestation) + 0.9425). On the basis of the estimated maternal age- and gestational age-related risks, the expected number of trisomy 21 cases at 10-14 weeks of gestation in the 96,127 pregnancies was 329 (95% confidence interval 291-361), which was not significantly different from the observed number of 326 cases (chi2 = 0.02). CONCLUSION: The risk for trisomy 21 increases with maternal age and decreases with gestation. The prevalence of trisomy 21 at 12 and 16 weeks of gestation is higher than the prevalence at 40 weeks by 30% and 21%, respectively.  (+info)

Is maternal age a risk factor for mental retardation among children? (8/2227)

The purpose of this study was to determine whether older or very young maternal age at delivery is associated with mental retardation in children. Ten-year-old children with mental retardation (an intelligence quotient of 70 or less) were identified in 1985-1987 from multiple sources in the metropolitan Atlanta, Georgia, area. These children were subdivided into two case groups according to whether they had concomitant developmental disabilities or birth defects affecting the central nervous system (codevelopmental retardation) or did not have such disabilities (isolated retardation). Control children were randomly chosen from the regular education files of the public school systems in the study area. Data on sociodemographic variables were gathered from birth certificates. Children of teenaged mothers were not at increased risk for either form of retardation and children of mothers aged > or =30 years were not at increased risk for isolated retardation, in comparison with children of mothers aged 20-29 years. A markedly elevated risk of codevelopmental retardation was seen among black children of mothers aged > or =30 years that was not attributable to Down syndrome. A modest increase in risk for codevelopmental retardation was observed among white children born to older mothers, but it was entirely due to Down syndrome.  (+info)

Maternal age is a term used to describe the age of a woman at the time she becomes pregnant or gives birth. It is often used in medical and epidemiological contexts to discuss the potential risks, complications, and outcomes associated with pregnancy and childbirth at different stages of a woman's reproductive years.

Advanced maternal age typically refers to women who become pregnant or give birth at 35 years of age or older. This group faces an increased risk for certain chromosomal abnormalities, such as Down syndrome, and other pregnancy-related complications, including gestational diabetes, preeclampsia, and cesarean delivery.

On the other end of the spectrum, adolescent pregnancies (those that occur in women under 20 years old) also come with their own set of potential risks and complications, such as preterm birth, low birth weight, and anemia.

It's important to note that while maternal age can influence pregnancy outcomes, many other factors – including genetics, lifestyle choices, and access to quality healthcare – can also play a significant role in determining the health of both mother and baby during pregnancy and childbirth.

Pregnancy is a physiological state or condition where a fertilized egg (zygote) successfully implants and grows in the uterus of a woman, leading to the development of an embryo and finally a fetus. This process typically spans approximately 40 weeks, divided into three trimesters, and culminates in childbirth. Throughout this period, numerous hormonal and physical changes occur to support the growing offspring, including uterine enlargement, breast development, and various maternal adaptations to ensure the fetus's optimal growth and well-being.

"Paternal age" is a term used to describe the age of a father at the time of conception. It is often considered in relation to the potential impact on genetic health and the risk of certain genetic conditions in offspring. As a father's age increases, there is a higher chance of mutations occurring during the formation of sperm cells, which can potentially lead to an increased risk of certain genetic disorders such as Apert syndrome, Crouzon syndrome, and Schinzel-Giedion midface retraction syndrome. However, it is important to note that while the risk does increase with paternal age, the overall likelihood remains relatively low.

Down syndrome is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. It is characterized by intellectual and developmental disabilities, distinctive facial features, and sometimes physical growth delays and health problems. The condition affects approximately one in every 700 babies born in the United States.

Individuals with Down syndrome have varying degrees of cognitive impairment, ranging from mild to moderate or severe. They may also have delayed development, including late walking and talking, and may require additional support and education services throughout their lives.

People with Down syndrome are at increased risk for certain health conditions, such as congenital heart defects, respiratory infections, hearing loss, vision problems, gastrointestinal issues, and thyroid disorders. However, many individuals with Down syndrome live healthy and fulfilling lives with appropriate medical care and support.

The condition is named after John Langdon Down, an English physician who first described the syndrome in 1866.

Birth order is a term that refers to the sequence in which a person is born in their family, specifically in relation to their siblings. It is used in psychology and sociology to describe the various personality traits, behaviors, and developmental milestones that have been associated with being the firstborn, middle child, youngest child, or an only child.

For example, some studies suggest that firstborn children tend to be more responsible, achievement-oriented, and socially dominant than their younger siblings, while later-born children may be more easygoing, adventurous, and rebellious. However, it's important to note that these patterns are not universal and can be influenced by a variety of factors, including family size, spacing between siblings, gender, parenting style, and individual temperament.

Overall, birth order is just one factor among many that contribute to a person's development and identity, and should not be used as a definitive predictor of their traits or behaviors.

High-risk pregnancy is a term used to describe a situation where the mother or the fetus has an increased risk of developing complications during pregnancy, labor, delivery, or in the postpartum period. These risks may be due to pre-existing medical conditions in the mother, such as diabetes, hypertension, heart disease, kidney disease, autoimmune disorders, or infectious diseases like HIV/AIDS. Other factors that can contribute to a high-risk pregnancy include advanced maternal age (35 years and older), obesity, multiple gestations (twins, triplets, etc.), fetal growth restriction, placental issues, and a history of previous pregnancy complications or preterm labor.

High-risk pregnancies require specialized care and monitoring by healthcare professionals, often involving maternal-fetal medicine specialists, obstetricians, perinatologists, and neonatologists. Regular prenatal care, frequent checkups, ultrasound monitoring, and sometimes additional testing and interventions may be necessary to ensure the best possible outcomes for both the mother and the baby.

A newborn infant is a baby who is within the first 28 days of life. This period is also referred to as the neonatal period. Newborns require specialized care and attention due to their immature bodily systems and increased vulnerability to various health issues. They are closely monitored for signs of well-being, growth, and development during this critical time.

Amniocentesis is a medical procedure in which a small amount of amniotic fluid, which contains fetal cells, is withdrawn from the uterus through a hollow needle inserted into the abdomen of a pregnant woman. This procedure is typically performed between the 16th and 20th weeks of pregnancy.

The main purpose of amniocentesis is to diagnose genetic disorders and chromosomal abnormalities in the developing fetus, such as Down syndrome, Edwards syndrome, and neural tube defects. The fetal cells obtained from the amniotic fluid can be cultured and analyzed for various genetic characteristics, including chromosomal structure and number, as well as specific gene mutations.

Amniocentesis carries a small risk of complications, such as miscarriage, infection, or injury to the fetus. Therefore, it is generally offered to women who have an increased risk of having a baby with a genetic disorder or chromosomal abnormality, such as those over the age of 35, those with a family history of genetic disorders, or those who have had a previous pregnancy affected by a genetic condition.

It's important to note that while amniocentesis can provide valuable information about the health of the fetus, it does not guarantee a completely normal baby, and there are some risks associated with the procedure. Therefore, the decision to undergo amniocentesis should be made carefully, in consultation with a healthcare provider, taking into account the individual circumstances and preferences of each woman.

In medical terms, parity refers to the number of times a woman has given birth to a viable fetus, usually defined as a pregnancy that reaches at least 20 weeks' gestation. It is often used in obstetrics and gynecology to describe a woman's childbearing history and to assess potential risks associated with childbirth.

Parity is typically categorized as follows:

* Nulliparous: A woman who has never given birth to a viable fetus.
* Primiparous: A woman who has given birth to one viable fetus.
* Multiparous: A woman who has given birth to more than one viable fetus.

In some cases, parity may also consider the number of pregnancies that resulted in stillbirths or miscarriages, although this is not always the case. It's important to note that parity does not necessarily reflect the total number of pregnancies a woman has had, only those that resulted in viable births.

Pregnancy outcome refers to the final result or status of a pregnancy, including both the health of the mother and the newborn baby. It can be categorized into various types such as:

1. Live birth: The delivery of one or more babies who show signs of life after separation from their mother.
2. Stillbirth: The delivery of a baby who has died in the womb after 20 weeks of pregnancy.
3. Miscarriage: The spontaneous loss of a pregnancy before the 20th week.
4. Abortion: The intentional termination of a pregnancy before the fetus can survive outside the uterus.
5. Ectopic pregnancy: A pregnancy that develops outside the uterus, usually in the fallopian tube, which is not viable and requires medical attention.
6. Preterm birth: The delivery of a baby before 37 weeks of gestation, which can lead to various health issues for the newborn.
7. Full-term birth: The delivery of a baby between 37 and 42 weeks of gestation.
8. Post-term pregnancy: The delivery of a baby after 42 weeks of gestation, which may increase the risk of complications for both mother and baby.

The pregnancy outcome is influenced by various factors such as maternal age, health status, lifestyle habits, genetic factors, and access to quality prenatal care.

Birth weight refers to the first weight of a newborn infant, usually taken immediately after birth. It is a critical vital sign that indicates the baby's health status and is used as a predictor for various short-term and long-term health outcomes.

Typically, a full-term newborn's weight ranges from 5.5 to 8.8 pounds (2.5 to 4 kg), although normal birth weights can vary significantly based on factors such as gestational age, genetics, maternal health, and nutrition. Low birth weight is defined as less than 5.5 pounds (2.5 kg), while high birth weight is greater than 8.8 pounds (4 kg).

Low birth weight babies are at a higher risk for various medical complications, including respiratory distress syndrome, jaundice, infections, and developmental delays. High birth weight babies may face challenges with delivery, increased risk of obesity, and potential metabolic issues later in life. Regular prenatal care is essential to monitor fetal growth and ensure a healthy pregnancy and optimal birth weight for the baby.

Gestational age is the length of time that has passed since the first day of the last menstrual period (LMP) in pregnant women. It is the standard unit used to estimate the age of a pregnancy and is typically expressed in weeks. This measure is used because the exact date of conception is often not known, but the start of the last menstrual period is usually easier to recall.

It's important to note that since ovulation typically occurs around two weeks after the start of the LMP, gestational age is approximately two weeks longer than fetal age, which is the actual time elapsed since conception. Medical professionals use both gestational and fetal age to track the development and growth of the fetus during pregnancy.

Prenatal diagnosis is the medical testing of fetuses, embryos, or pregnant women to detect the presence or absence of certain genetic disorders or birth defects. These tests can be performed through various methods such as chorionic villus sampling (CVS), amniocentesis, or ultrasound. The goal of prenatal diagnosis is to provide early information about the health of the fetus so that parents and healthcare providers can make informed decisions about pregnancy management and newborn care. It allows for early intervention, treatment, or planning for the child's needs after birth.

Trisomy is a genetic condition where there is an extra copy of a particular chromosome, resulting in 47 chromosomes instead of the typical 46 in a cell. This usually occurs due to an error in cell division during the development of the egg, sperm, or embryo.

Instead of the normal pair, there are three copies (trisomy) of that chromosome. The most common form of trisomy is Trisomy 21, also known as Down syndrome, where there is an extra copy of chromosome 21. Other forms include Trisomy 13 (Patau syndrome) and Trisomy 18 (Edwards syndrome), which are associated with more severe developmental issues and shorter lifespans.

Trisomy can also occur in a mosaic form, where some cells have the extra chromosome while others do not, leading to varying degrees of symptoms depending on the proportion of affected cells.

The first trimester of pregnancy is defined as the period of gestational development that extends from conception (fertilization of the egg by sperm) to the end of the 13th week. This critical phase marks significant transformations in both the mother's body and the growing embryo/fetus.

During the first trimester, the fertilized egg implants into the uterine lining (implantation), initiating a series of complex interactions leading to the formation of the placenta - an organ essential for providing nutrients and oxygen to the developing fetus while removing waste products. Simultaneously, the embryo undergoes rapid cell division and differentiation, giving rise to various organs and systems. By the end of the first trimester, most major structures are present, although they continue to mature and grow throughout pregnancy.

The mother may experience several physiological changes during this time, including:
- Morning sickness (nausea and vomiting)
- Fatigue
- Breast tenderness
- Frequent urination
- Food aversions or cravings
- Mood swings

Additionally, hormonal shifts can cause various symptoms and prepare the body for potential changes in lactation, posture, and pelvic alignment as pregnancy progresses. Regular prenatal care is crucial during this period to monitor both maternal and fetal wellbeing, identify any potential complications early on, and provide appropriate guidance and support throughout the pregnancy.

Pregnancy complications refer to any health problems that arise during pregnancy which can put both the mother and the baby at risk. These complications may occur at any point during the pregnancy, from conception until childbirth. Some common pregnancy complications include:

1. Gestational diabetes: a type of diabetes that develops during pregnancy in women who did not have diabetes before becoming pregnant.
2. Preeclampsia: a pregnancy complication characterized by high blood pressure and damage to organs such as the liver or kidneys.
3. Placenta previa: a condition where the placenta covers the cervix, which can cause bleeding and may require delivery via cesarean section.
4. Preterm labor: when labor begins before 37 weeks of gestation, which can lead to premature birth and other complications.
5. Intrauterine growth restriction (IUGR): a condition where the fetus does not grow at a normal rate inside the womb.
6. Multiple pregnancies: carrying more than one baby, such as twins or triplets, which can increase the risk of premature labor and other complications.
7. Rh incompatibility: a condition where the mother's blood type is different from the baby's, which can cause anemia and jaundice in the newborn.
8. Pregnancy loss: including miscarriage, stillbirth, or ectopic pregnancy, which can be emotionally devastating for the parents.

It is important to monitor pregnancy closely and seek medical attention promptly if any concerning symptoms arise. With proper care and management, many pregnancy complications can be treated effectively, reducing the risk of harm to both the mother and the baby.

Congenital abnormalities, also known as birth defects, are structural or functional anomalies that are present at birth. These abnormalities can develop at any point during fetal development, and they can affect any part of the body. They can be caused by genetic factors, environmental influences, or a combination of both.

Congenital abnormalities can range from mild to severe and may include structural defects such as heart defects, neural tube defects, and cleft lip and palate, as well as functional defects such as intellectual disabilities and sensory impairments. Some congenital abnormalities may be visible at birth, while others may not become apparent until later in life.

In some cases, congenital abnormalities may be detected through prenatal testing, such as ultrasound or amniocentesis. In other cases, they may not be diagnosed until after the baby is born. Treatment for congenital abnormalities varies depending on the type and severity of the defect, and may include surgery, therapy, medication, or a combination of these approaches.

Nondisjunction is a genetic term that refers to the failure of homologous chromosomes or sister chromatids to properly separate during cell division, resulting in an abnormal number of chromosomes in the daughter cells. This can occur during either mitosis (resulting in somatic mutations) or meiosis (leading to gametes with an incorrect number of chromosomes).

In humans, nondisjunction of chromosome 21 during meiosis is the most common cause of Down syndrome, resulting in three copies of chromosome 21 (trisomy 21) in the affected individual. Nondisjunction can also result in other aneuploidies, such as Turner syndrome (X monosomy), Klinefelter syndrome (XXY), and Edwards syndrome (trisomy 18).

Nondisjunction is typically a random event, although maternal age has been identified as a risk factor for nondisjunction during meiosis. In some cases, structural chromosomal abnormalities or genetic factors may predispose an individual to nondisjunction events.

Spontaneous abortion, also known as miscarriage, is the unintentional expulsion of a nonviable fetus from the uterus before the 20th week of gestation. It is a common complication of early pregnancy, with most miscarriages occurring during the first trimester. Spontaneous abortion can have various causes, including chromosomal abnormalities, maternal health conditions, infections, hormonal imbalances, and structural issues of the uterus or cervix. In many cases, the exact cause may remain unknown.

The symptoms of spontaneous abortion can vary but often include vaginal bleeding, which may range from light spotting to heavy bleeding; abdominal pain or cramping; and the passing of tissue or clots from the vagina. While some miscarriages occur suddenly and are immediately noticeable, others may progress slowly over several days or even weeks.

In medical practice, healthcare providers often use specific terminology to describe different stages and types of spontaneous abortion. For example:

* Threatened abortion: Vaginal bleeding during early pregnancy, but the cervix remains closed, and there is no evidence of fetal demise or passing of tissue.
* Inevitable abortion: Vaginal bleeding with an open cervix, indicating that a miscarriage is imminent or already in progress.
* Incomplete abortion: The expulsion of some but not all products of conception from the uterus, requiring medical intervention to remove any remaining tissue.
* Complete abortion: The successful passage of all products of conception from the uterus, often confirmed through an ultrasound or pelvic examination.
* Missed abortion: The death of a fetus in the uterus without any expulsion of the products of conception, which may be discovered during routine prenatal care.
* Septic abortion: A rare and life-threatening complication of spontaneous abortion characterized by infection of the products of conception and the surrounding tissues, requiring prompt medical attention and antibiotic treatment.

Healthcare providers typically monitor patients who experience a spontaneous abortion to ensure that all products of conception have been expelled and that there are no complications, such as infection or excessive bleeding. In some cases, medication or surgical intervention may be necessary to remove any remaining tissue or address other issues related to the miscarriage. Counseling and support services are often available for individuals and couples who experience a spontaneous abortion, as they may face emotional challenges and concerns about future pregnancies.

A birth certificate is an official document that serves as legal proof of a person's birth and provides important information about the individual, including their full name, date and place of birth, sex, parents' names, and other identifying details. In medical terms, a birth certificate may be used to establish a patient's identity, age, and other relevant demographic information.

Birth certificates are typically issued by the government agency responsible for vital records in the jurisdiction where the individual was born, such as a state or county health department. They are considered legal documents and are often required for various purposes, such as enrolling in school, applying for a passport, or obtaining government benefits.

It is important to note that birth certificates may be amended or corrected if there are errors or discrepancies in the information they contain. In some cases, individuals may also need to obtain certified copies of their birth certificate from the appropriate government agency in order to provide proof of their identity or other personal information.

Crown-rump length (CRL) is a medical measurement used in obstetrics to estimate the age of a developing fetus. It refers to the length from the top of the head (crown) to the bottom of the buttocks (rump). This measurement is typically taken during an ultrasound examination in the first trimester of pregnancy, between 8 and 13 weeks of gestation.

The CRL is used to calculate the estimated due date and to monitor fetal growth and development. It can also help identify potential issues or abnormalities in fetal development. As the pregnancy progresses, other measurements such as head circumference, abdominal circumference, and femur length are used to assess fetal growth and development.

Nuchal translucency measurement (NT) is a prenatal ultrasound assessment used to screen for chromosomal abnormalities, particularly Down syndrome (Trisomy 21), and other fetal abnormalities. The nuchal translucency refers to the sonolucent space or fluid-filled area at the back of the neck of a developing fetus. During the first trimester of pregnancy, an increased nuchal translucency measurement may indicate an increased risk for certain genetic disorders and structural defects.

The procedure involves measuring the thickness of this fluid-filled space using ultrasound imaging, typically between 11 and 14 weeks of gestation. A larger nuchal translucency measurement (usually greater than 3 mm) may suggest an increased risk for chromosomal abnormalities or structural issues in the fetus. The NT measurement is often combined with maternal age, biochemical markers (such as PAPP-A and free beta-hCG), and sometimes first-trimester fetal heart rate assessment to calculate the overall risk of chromosomal abnormalities in the fetus.

It's important to note that while an increased nuchal translucency measurement can indicate a higher risk for genetic disorders, it does not confirm their presence. Further diagnostic testing, such as chorionic villus sampling (CVS) or amniocentesis, may be recommended to obtain a definitive diagnosis.

Aneuploidy is a medical term that refers to an abnormal number of chromosomes in a cell. Chromosomes are thread-like structures located inside the nucleus of cells that contain genetic information in the form of genes.

In humans, the normal number of chromosomes in a cell is 46, arranged in 23 pairs. Aneuploidy occurs when there is an extra or missing chromosome in one or more of these pairs. For example, Down syndrome is a condition that results from an extra copy of chromosome 21, also known as trisomy 21.

Aneuploidy can arise during the formation of gametes (sperm or egg cells) due to errors in the process of cell division called meiosis. These errors can result in eggs or sperm with an abnormal number of chromosomes, which can then lead to aneuploidy in the resulting embryo.

Aneuploidy is a significant cause of birth defects and miscarriages. The severity of the condition depends on which chromosomes are affected and the extent of the abnormality. In some cases, aneuploidy may have no noticeable effects, while in others it can lead to serious health problems or developmental delays.

Chromosome disorders are a group of genetic conditions caused by abnormalities in the number or structure of chromosomes. Chromosomes are thread-like structures located in the nucleus of cells that contain most of the body's genetic material, which is composed of DNA and proteins. Normally, humans have 23 pairs of chromosomes, for a total of 46 chromosomes.

Chromosome disorders can result from changes in the number of chromosomes (aneuploidy) or structural abnormalities in one or more chromosomes. Some common examples of chromosome disorders include:

1. Down syndrome: a condition caused by an extra copy of chromosome 21, resulting in intellectual disability, developmental delays, and distinctive physical features.
2. Turner syndrome: a condition that affects only females and is caused by the absence of all or part of one X chromosome, resulting in short stature, lack of sexual development, and other symptoms.
3. Klinefelter syndrome: a condition that affects only males and is caused by an extra copy of the X chromosome, resulting in tall stature, infertility, and other symptoms.
4. Cri-du-chat syndrome: a condition caused by a deletion of part of the short arm of chromosome 5, resulting in intellectual disability, developmental delays, and a distinctive cat-like cry.
5. Fragile X syndrome: a condition caused by a mutation in the FMR1 gene on the X chromosome, resulting in intellectual disability, behavioral problems, and physical symptoms.

Chromosome disorders can be diagnosed through various genetic tests, such as karyotyping, chromosomal microarray analysis (CMA), or fluorescence in situ hybridization (FISH). Treatment for these conditions depends on the specific disorder and its associated symptoms and may include medical interventions, therapies, and educational support.

Medical Definition:

"Risk factors" are any attribute, characteristic or exposure of an individual that increases the likelihood of developing a disease or injury. They can be divided into modifiable and non-modifiable risk factors. Modifiable risk factors are those that can be changed through lifestyle choices or medical treatment, while non-modifiable risk factors are inherent traits such as age, gender, or genetic predisposition. Examples of modifiable risk factors include smoking, alcohol consumption, physical inactivity, and unhealthy diet, while non-modifiable risk factors include age, sex, and family history. It is important to note that having a risk factor does not guarantee that a person will develop the disease, but rather indicates an increased susceptibility.

A Cesarean section, often referred to as a C-section, is a surgical procedure used to deliver a baby. It involves making an incision through the mother's abdomen and uterus to remove the baby. This procedure may be necessary when a vaginal delivery would put the mother or the baby at risk.

There are several reasons why a C-section might be recommended, including:

* The baby is in a breech position (feet first) or a transverse position (sideways) and cannot be turned to a normal head-down position.
* The baby is too large to safely pass through the mother's birth canal.
* The mother has a medical condition, such as heart disease or high blood pressure, that could make vaginal delivery risky.
* The mother has an infection, such as HIV or herpes, that could be passed to the baby during a vaginal delivery.
* The labor is not progressing and there are concerns about the health of the mother or the baby.

C-sections are generally safe for both the mother and the baby, but like any surgery, they do carry some risks. These can include infection, bleeding, blood clots, and injury to nearby organs. In addition, women who have a C-section are more likely to experience complications in future pregnancies, such as placenta previa or uterine rupture.

If you have questions about whether a C-section is necessary for your delivery, it's important to discuss your options with your healthcare provider.

The second trimester of pregnancy is the period between the completion of 12 weeks (the end of the first trimester) and 26 weeks (the beginning of the third trimester) of gestational age. It is often considered the most comfortable period for many pregnant women as the risk of miscarriage decreases significantly, and the symptoms experienced during the first trimester, such as nausea and fatigue, typically improve.

During this time, the uterus expands above the pubic bone, allowing more space for the growing fetus. The fetal development in the second trimester includes significant growth in size and weight, formation of all major organs, and the beginning of movement sensations that the mother can feel. Additionally, the fetus starts to hear, swallow and kick, and the skin is covered with a protective coating called vernix.

Prenatal care during this period typically includes regular prenatal appointments to monitor the mother's health and the baby's growth and development. These appointments may include measurements of the uterus, fetal heart rate monitoring, and screening tests for genetic disorders or other potential issues.

Low birth weight is a term used to describe babies who are born weighing less than 5 pounds, 8 ounces (2,500 grams). It's often defined as a birth weight of 2,499 grams or less. This can be further categorized into very low birth weight (less than 1,500 grams) and extremely low birth weight (less than 1,000 grams). Low birth weight is most commonly caused by premature birth, but it can also be caused by growth restriction in the womb. These babies are at risk for numerous health complications, both in the short and long term.

Prenatal ultrasonography, also known as obstetric ultrasound, is a medical diagnostic procedure that uses high-frequency sound waves to create images of the developing fetus, placenta, and amniotic fluid inside the uterus. It is a non-invasive and painless test that is widely used during pregnancy to monitor the growth and development of the fetus, detect any potential abnormalities or complications, and determine the due date.

During the procedure, a transducer (a small handheld device) is placed on the mother's abdomen and moved around to capture images from different angles. The sound waves travel through the mother's body and bounce back off the fetus, producing echoes that are then converted into electrical signals and displayed as images on a screen.

Prenatal ultrasonography can be performed at various stages of pregnancy, including early pregnancy to confirm the pregnancy and detect the number of fetuses, mid-pregnancy to assess the growth and development of the fetus, and late pregnancy to evaluate the position of the fetus and determine if it is head down or breech. It can also be used to guide invasive procedures such as amniocentesis or chorionic villus sampling.

Overall, prenatal ultrasonography is a valuable tool in modern obstetrics that helps ensure the health and well-being of both the mother and the developing fetus.

Infant Mortality is the death of a baby before their first birthday. The infant mortality rate is typically expressed as the number of deaths per 1,000 live births. This is a key indicator of the overall health of a population and is often used to measure the well-being of children in a society.

Infant mortality can be further categorized into neonatal mortality (death within the first 28 days of life) and postneonatal mortality (death after 28 days of life but before one year). The main causes of infant mortality vary by country and region, but generally include premature birth, low birth weight, congenital anomalies, sudden infant death syndrome (SIDS), and infectious diseases.

Reducing infant mortality is a major public health goal for many countries, and efforts to improve maternal and child health, access to quality healthcare, and socioeconomic conditions are crucial in achieving this goal.

Chorionic Gonadotropin, beta Subunit, Human (β-hCG) is a protein that is produced by the placenta during pregnancy. It is a component of human chorionic gonadotropin (hCG), which is a hormone that is composed of two subunits: alpha and beta. The β-hCG subunit is specific to hCG and is not found in other hormones, making it a useful marker for pregnancy and certain medical conditions.

During early pregnancy, the levels of β-hCG increase rapidly and can be detected in the blood and urine. This has led to the development of pregnancy tests that detect the presence of β-hCG to confirm pregnancy. In addition to its role in pregnancy, β-hCG is also used as a tumor marker for certain types of cancer, such as germ cell tumors and choriocarcinoma.

Elevated levels of β-hCG may indicate the presence of a molar pregnancy, a condition in which a fertilized egg implants in the uterus but does not develop properly. In some cases, a molar pregnancy can become cancerous and require treatment. Therefore, monitoring β-hCG levels during pregnancy is important for detecting any potential complications.

Multiple pregnancy is a type of gestation where more than one fetus is carried simultaneously in the uterus. The most common forms of multiple pregnancies are twins (two fetuses), triplets (three fetuses), and quadruplets (four fetuses). Multiple pregnancies can occur when a single fertilized egg splits into two or more embryos (monozygotic) or when more than one egg is released and gets fertilized during ovulation (dizygotic). The risk of multiple pregnancies increases with the use of assisted reproductive technologies, such as in vitro fertilization. Multiple pregnancies are associated with higher risks for both the mother and the fetuses, including preterm labor, low birth weight, and other complications.

Fetal death, also known as stillbirth or intrauterine fetal demise, is defined as the death of a fetus at 20 weeks of gestation or later. The criteria for defining fetal death may vary slightly by country and jurisdiction, but in general, it refers to the loss of a pregnancy after the point at which the fetus is considered viable outside the womb.

Fetal death can occur for a variety of reasons, including chromosomal abnormalities, placental problems, maternal health conditions, infections, and umbilical cord accidents. In some cases, the cause of fetal death may remain unknown.

The diagnosis of fetal death is typically made through ultrasound or other imaging tests, which can confirm the absence of a heartbeat or movement in the fetus. Once fetal death has been diagnosed, medical professionals will work with the parents to determine the best course of action for managing the pregnancy and delivering the fetus. This may involve waiting for labor to begin naturally, inducing labor, or performing a cesarean delivery.

Experiencing a fetal death can be a very difficult and emotional experience for parents, and it is important for them to receive supportive care from their healthcare providers, family members, and friends. Grief counseling and support groups may also be helpful in coping with the loss.

A premature birth is defined as the delivery of a baby before 37 weeks of gestation. This can occur spontaneously or as a result of medical intervention due to maternal or fetal complications. Premature babies, also known as preemies, may face various health challenges depending on how early they are born and their weight at birth. These challenges can include respiratory distress syndrome, jaundice, anemia, issues with feeding and digestion, developmental delays, and vision problems. With advancements in medical care and neonatal intensive care units (NICUs), many premature babies survive and go on to lead healthy lives.

I believe there may be a misunderstanding in your question. "Mothers" is a term that refers to individuals who have given birth to and raised children. It is not a medical term with a specific definition. If you are referring to a different word or term, please clarify so I can provide a more accurate response.

Pregnancy-associated plasma protein-A (PAPP-A) is a protease that is often used as a biomarker in early pregnancy. It is a protein that is produced by the placenta and can be detected in the mother's bloodstream during pregnancy.

In early pregnancy, low levels of PAPP-A may indicate an increased risk for certain complications, such as preeclampsia or fetal growth restriction. High levels of PAPP-A, on the other hand, may be associated with an increased risk of chromosomal abnormalities, such as Down syndrome.

It is important to note that while PAPP-A levels can provide valuable information about the health of a pregnancy, they are just one piece of the puzzle and should be considered in conjunction with other factors, such as maternal age, medical history, and ultrasound results. Your healthcare provider will use this information along with other tests to assess your risk for certain complications and develop an appropriate plan of care.

An umbilical hernia is a type of hernia that occurs at the umbilicus, or belly button. It results from a protrusion of abdominal contents through a weakened area in the abdominal wall surrounding the navel. This condition is common in newborns and infants, especially premature babies, due to incomplete closure of the abdominal muscles during development.

In most cases, umbilical hernias in children close on their own by age 3-4 or by the time they reach school age. However, if the hernia is still present after this age, surgical intervention may be required to prevent potential complications such as incarceration (where the herniated tissue becomes trapped and cannot be pushed back in) or strangulation (where the blood supply to the herniated tissue is cut off, leading to tissue death).

Adults can also develop umbilical hernias, often as a result of increased pressure in the abdomen due to obesity, pregnancy, heavy lifting, or persistent coughing. Umbilical hernias in adults are generally more likely to require surgical repair due to the higher risk of complications.

Gastroschisis is a congenital abdominal wall defect, characterized by an opening, usually to the right of the umbilical cord, through which the abdominal organs such as the intestines protrude. It's typically not covered by a sac or membrane. The exact cause of gastroschisis is unknown, but it's thought to be related to disrupted blood flow in the area where the abdominal wall develops during pregnancy. This condition is usually detected prenatally through ultrasound and requires surgical repair shortly after birth.

Preimplantation Diagnosis (PID) is a genetic testing procedure performed on embryos created through in vitro fertilization (IVF), before they are implanted in the uterus. The purpose of PID is to identify genetic disorders or chromosomal abnormalities in the embryos, allowing only those free of such issues to be transferred to the uterus, thereby reducing the risk of passing on genetic diseases to offspring. It involves biopsying one or more cells from an embryo and analyzing its DNA for specific genetic disorders or chromosomal abnormalities. PID is often recommended for couples with a known history of genetic disorders or those who have experienced multiple miscarriages or failed IVF cycles.

Prenatal care is a type of preventive healthcare that focuses on providing regular check-ups and medical care to pregnant women, with the aim of ensuring the best possible health outcomes for both the mother and the developing fetus. It involves routine prenatal screenings and tests, such as blood pressure monitoring, urine analysis, weight checks, and ultrasounds, to assess the progress of the pregnancy and identify any potential health issues or complications early on.

Prenatal care also includes education and counseling on topics such as nutrition, exercise, and lifestyle choices that can affect pregnancy outcomes. It may involve referrals to specialists, such as obstetricians, perinatologists, or maternal-fetal medicine specialists, for high-risk pregnancies.

Overall, prenatal care is an essential component of ensuring a healthy pregnancy and reducing the risk of complications during childbirth and beyond.

Fertilization in vitro, also known as in-vitro fertilization (IVF), is a medical procedure where an egg (oocyte) and sperm are combined in a laboratory dish to facilitate fertilization. The fertilized egg (embryo) is then transferred to a uterus with the hope of establishing a successful pregnancy. This procedure is often used when other assisted reproductive technologies have been unsuccessful or are not applicable, such as in cases of blocked fallopian tubes, severe male factor infertility, and unexplained infertility. The process involves ovarian stimulation, egg retrieval, fertilization, embryo culture, and embryo transfer. In some cases, additional techniques such as intracytoplasmic sperm injection (ICSI) or preimplantation genetic testing (PGT) may be used to increase the chances of success.

A live birth is the complete expulsion or extraction from its mother of a product of human conception, irrespective of the duration of the pregnancy, that, after such separation, breathes or shows any other evidence of life - such as beating of the heart, pulsation of the umbilical cord, or definite movement of voluntary muscles - whether or not the umbilical cord has been cut or the placenta is attached.

This definition is used by the World Health Organization (WHO) and most national statistical agencies to distinguish live births from stillbirths. It's important to note that in some medical contexts, a different definition of live birth may be used.

A stillbirth is defined as the delivery of a baby who has died in the womb after 20 weeks of pregnancy. The baby may die at any time during the pregnancy, but death must occur after 20 weeks to be classified as a stillbirth. Stillbirths can have many different causes, including problems with the placenta or umbilical cord, chromosomal abnormalities, infections, and birth defects. In some cases, the cause of a stillbirth may not be able to be determined.

Stillbirth is a tragic event that can have significant emotional and psychological impacts on the parents and other family members. It is important for healthcare providers to offer support and resources to help families cope with their loss. This may include counseling, support groups, and information about memorializing their baby.

Perinatal mortality is the death of a baby around the time of birth. It specifically refers to stillbirths (fetal deaths at 28 weeks of gestation or more) and deaths in the first week of life (early neonatal deaths). The perinatal period is defined as beginning at 22 weeks (154 days) of gestation and ending 7 completed days after birth. Perinatal mortality rate is the number of perinatal deaths during this period, expressed per 1000 total births (live births + stillbirths). High perinatal mortality rates can indicate poor quality of care during pregnancy and childbirth.

Birth intervals refer to the length of time between the birth of one child and the conception of the next child. It is the duration from the delivery of one baby to the initiation of the pregnancy that results in another birth. This interval is an essential measure in reproductive health, as it can impact the health and well-being of both the mother and the children.

The World Health Organization (WHO) recommends a minimum birth interval of 24 months between pregnancies to reduce the risk of adverse maternal and perinatal outcomes. Shorter birth intervals are associated with increased risks for preterm birth, low birth weight, small for gestational age, and neonatal mortality. Additionally, short birth intervals can also negatively affect the mother's health, increasing the risk of maternal depletion syndrome, which may lead to nutritional deficiencies, anemia, and fatigue.

Birth intervals are influenced by various factors, including cultural norms, socioeconomic status, access to family planning services, and individual preferences. Encouraging longer birth intervals through improved access to family planning resources and education can contribute to better maternal and child health outcomes.

Assisted reproductive techniques (ART) are medical procedures that involve the handling of human sperm and ova to establish a pregnancy. These techniques are used when other methods of achieving pregnancy have failed or are not available. Examples of ART include in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), gamete intrafallopian transfer (GIFT), and zygote intrafallopian transfer (ZIFT). These procedures may be used to treat infertility, prevent genetic disorders, or to help same-sex couples or single people have children. It is important to note that the use of ART can involve significant physical, emotional, and financial costs, and it may not always result in a successful pregnancy.

Small for Gestational Age (SGA) is a term used in pediatrics to describe newborn infants who are smaller in size than expected for the number of weeks they have been in the womb. It is typically defined as a baby whose weight is below the 10th percentile for its gestational age. SGA can be further classified into two categories: constitutionally small (also known as physiologically small) and pathologically small. Constitutionally small infants are those who are genetically predisposed to being smaller, while pathologically small infants have a growth restriction due to factors such as placental insufficiency, maternal hypertension, or chromosomal abnormalities.

It is important to note that SGA is not the same as premature birth. Premature babies are those born before 37 weeks of gestation, regardless of their size. However, a baby can be both premature and SGA.

Fetal diseases are medical conditions or abnormalities that affect a fetus during pregnancy. These diseases can be caused by genetic factors, environmental influences, or a combination of both. They can range from mild to severe and may impact various organ systems in the developing fetus. Examples of fetal diseases include congenital heart defects, neural tube defects, chromosomal abnormalities such as Down syndrome, and infectious diseases such as toxoplasmosis or rubella. Fetal diseases can be diagnosed through prenatal testing, including ultrasound, amniocentesis, and chorionic villus sampling. Treatment options may include medication, surgery, or delivery of the fetus, depending on the nature and severity of the disease.

An "eugenic abortion" is not a medical term, but rather a descriptive phrase that combines two concepts: eugenics and abortion.

Eugenics refers to the belief and practice of improving the human species by encouraging reproduction of individuals with desired traits and preventing reproduction of those with undesired traits. This concept has been widely criticized for its potential to be used as a tool for discrimination and oppression.

Abortion, on the other hand, is the medical procedure to end a pregnancy before the fetus can survive outside the womb.

A "eugenic abortion," therefore, generally refers to the practice of terminating a pregnancy based on the perceived genetic traits or characteristics of the fetus, such as disability, race, or sex. This phrase is often used in discussions about the ethics and morality of selective abortions, and it raises important questions about discrimination, reproductive rights, and medical ethics. It's worth noting that the vast majority of abortions are not performed for eugenic reasons, but rather due to a variety of personal, medical, and socioeconomic factors.

Pregnancy in adolescence, also known as teenage pregnancy, refers to a pregnancy that occurs in females under the age of 20. This can be further categorized into early adolescent pregnancy (occurring between ages 10-14), middle adolescent pregnancy (occurring between ages 15-17), and late adolescent pregnancy (occurring between ages 18-19). Teenage pregnancy is associated with higher risks of complications for both the mother and the baby, including preterm birth, low birth weight, and increased risk of neonatal mortality. Additionally, teenage mothers are more likely to drop out of school and face socioeconomic challenges.

Chromosome aberrations refer to structural and numerical changes in the chromosomes that can occur spontaneously or as a result of exposure to mutagenic agents. These changes can affect the genetic material encoded in the chromosomes, leading to various consequences such as developmental abnormalities, cancer, or infertility.

Structural aberrations include deletions, duplications, inversions, translocations, and rings, which result from breaks and rearrangements of chromosome segments. Numerical aberrations involve changes in the number of chromosomes, such as aneuploidy (extra or missing chromosomes) or polyploidy (multiples of a complete set of chromosomes).

Chromosome aberrations can be detected and analyzed using various cytogenetic techniques, including karyotyping, fluorescence in situ hybridization (FISH), and comparative genomic hybridization (CGH). These methods allow for the identification and characterization of chromosomal changes at the molecular level, providing valuable information for genetic counseling, diagnosis, and research.

Polar bodies are small, non-functional cells that are produced during the process of female meiosis, which results in the formation of an egg cell. They are formed when cytoplasmic divisions occur without subsequent cytokinesis, resulting in the separation of a small amount of cytoplasm and organelles from the main cell.

In the first meiotic division, a primary oocyte divides into a larger secondary oocyte and a smaller polar body, which contains half the number of chromosomes as the original cell. During the second meiotic division, the secondary oocyte divides into a larger ovum (egg) and another smaller polar body, again with half the number of chromosomes.

Polar bodies are typically extruded from the main cell and eventually disintegrate or are absorbed by surrounding cells. They do not contribute to the genetic makeup of the resulting egg or any offspring that may be produced from it. The formation of polar bodies helps ensure that the egg contains the correct number of chromosomes for normal development.

A cohort study is a type of observational study in which a group of individuals who share a common characteristic or exposure are followed up over time to determine the incidence of a specific outcome or outcomes. The cohort, or group, is defined based on the exposure status (e.g., exposed vs. unexposed) and then monitored prospectively to assess for the development of new health events or conditions.

Cohort studies can be either prospective or retrospective in design. In a prospective cohort study, participants are enrolled and followed forward in time from the beginning of the study. In contrast, in a retrospective cohort study, researchers identify a cohort that has already been assembled through medical records, insurance claims, or other sources and then look back in time to assess exposure status and health outcomes.

Cohort studies are useful for establishing causality between an exposure and an outcome because they allow researchers to observe the temporal relationship between the two. They can also provide information on the incidence of a disease or condition in different populations, which can be used to inform public health policy and interventions. However, cohort studies can be expensive and time-consuming to conduct, and they may be subject to bias if participants are not representative of the population or if there is loss to follow-up.

"Delivery, Obstetric" is a medical term that refers to the process of giving birth to a baby. It involves the passage of the fetus through the mother's vagina or via Caesarean section (C-section), which is a surgical procedure.

The obstetric delivery process typically includes three stages:

1. The first stage begins with the onset of labor and ends when the cervix is fully dilated.
2. The second stage starts with full dilation of the cervix and ends with the birth of the baby.
3. The third stage involves the delivery of the placenta, which is the organ that provides oxygen and nutrients to the developing fetus during pregnancy.

Obstetric delivery requires careful monitoring and management by healthcare professionals to ensure the safety and well-being of both the mother and the baby. Various interventions and techniques may be used during the delivery process to facilitate a safe and successful outcome, including the use of medications, assisted delivery with forceps or vacuum extraction, and C-section.

The birth rate is the number of live births that occur in a population during a specific period, usually calculated as the number of live births per 1,000 people per year. It is an important demographic indicator used to measure the growth or decline of a population over time. A higher birth rate indicates a younger population and faster population growth, while a lower birth rate suggests an older population and slower growth.

The birth rate can be affected by various factors, including socioeconomic conditions, cultural attitudes towards childbearing, access to healthcare services, and government policies related to family planning and reproductive health. It is also influenced by the age structure of the population, as women in their reproductive years (typically ages 15-49) are more likely to give birth.

It's worth noting that while the birth rate is an important indicator of population growth, it does not provide a complete picture of fertility rates or demographic trends. Other measures, such as the total fertility rate (TFR), which estimates the average number of children a woman would have during her reproductive years, are also used to analyze fertility patterns and population dynamics.

Human chromosome pair 21 consists of two rod-shaped structures present in the nucleus of each cell in the human body. Each member of the pair is a single chromosome, and they are identical to each other. Chromosomes are made up of DNA, which contains genetic information that determines many of an individual's traits and characteristics.

Chromosome pair 21 is one of the 23 pairs of human autosomal chromosomes, meaning they are not sex chromosomes (X or Y). Chromosome pair 21 is the smallest of the human chromosomes, and it contains approximately 48 million base pairs of DNA. It contains around 200-300 genes that provide instructions for making proteins and regulating various cellular processes.

Down syndrome, a genetic disorder characterized by intellectual disability, developmental delays, distinct facial features, and sometimes heart defects, is caused by an extra copy of chromosome pair 21 or a part of it. This additional genetic material can lead to abnormalities in brain development and function, resulting in the characteristic symptoms of Down syndrome.

Chorionic villi sampling (CVS) is a prenatal testing procedure that involves taking a small sample of the chorionic villi, which are finger-like projections of the placenta that contain fetal cells. The sample is then tested for genetic disorders and chromosomal abnormalities, such as Down syndrome.

CVS is typically performed between the 10th and 12th weeks of pregnancy and carries a small risk of miscarriage (about 1 in 100 to 1 in 200 procedures). The results of CVS can provide important information about the health of the fetus, allowing parents to make informed decisions about their pregnancy. However, it is important to note that CVS does not detect all genetic disorders and may produce false positive or false negative results in some cases. Therefore, follow-up testing may be necessary.

Obstetric labor complications refer to any physical or physiological difficulties that arise during the process of childbirth (labor) and can pose risks to the health of the mother, baby, or both. These complications may result from various factors such as pre-existing medical conditions, fetal distress, prolonged labor, abnormal positioning of the fetus, or issues related to the size or weight of the baby.

Some examples of obstetric labor complications include:

1. Fetal distress: This occurs when the fetus is not receiving adequate oxygen supply or is in danger during labor. It can be caused by various factors such as umbilical cord compression, placental abruption, or maternal anemia.
2. Prolonged labor: When labor lasts for more than 20 hours in first-time mothers or more than 14 hours in subsequent pregnancies, it is considered prolonged labor. This can lead to fatigue, infection, and other complications for both the mother and baby.
3. Abnormal positioning of the fetus: Normally, the fetus should be positioned head-down (vertex) before delivery. However, if the fetus is in a breech or transverse position, it can lead to difficult labor and increased risk of complications during delivery.
4. Shoulder dystocia: This occurs when the baby's shoulders get stuck behind the mother's pubic bone during delivery, making it challenging to deliver the baby. It can cause injuries to both the mother and the baby.
5. Placental abruption: This is a serious complication where the placenta separates from the uterus before delivery, leading to bleeding and potential oxygen deprivation for the fetus.
6. Uterine rupture: A rare but life-threatening complication where the uterus tears during labor, causing severe bleeding and potentially endangering both the mother and baby's lives.
7. Preeclampsia/eclampsia: This is a pregnancy-related hypertensive disorder that can lead to complications such as seizures, organ failure, or even maternal death if left untreated.
8. Postpartum hemorrhage: Excessive bleeding after delivery can be life-threatening and requires immediate medical attention.
9. Infections: Maternal infections during pregnancy or childbirth can lead to complications for both the mother and baby, including preterm labor, low birth weight, and even fetal death.
10. Anesthesia complications: Adverse reactions to anesthesia during delivery can cause respiratory depression, allergic reactions, or other complications that may endanger the mother's life.

In the field of medicine, twins are defined as two offspring produced by the same pregnancy. They can be either monozygotic (identical) or dizygotic (fraternal). Monozygotic twins develop from a single fertilized egg that splits into two separate embryos, resulting in individuals who share identical genetic material. Dizygotic twins, on the other hand, result from the fertilization of two separate eggs by two different sperm cells, leading to siblings who share about 50% of their genetic material, similar to non-twin siblings.

Logistic models, specifically logistic regression models, are a type of statistical analysis used in medical and epidemiological research to identify the relationship between the risk of a certain health outcome or disease (dependent variable) and one or more independent variables, such as demographic factors, exposure variables, or other clinical measurements.

In contrast to linear regression models, logistic regression models are used when the dependent variable is binary or dichotomous in nature, meaning it can only take on two values, such as "disease present" or "disease absent." The model uses a logistic function to estimate the probability of the outcome based on the independent variables.

Logistic regression models are useful for identifying risk factors and estimating the strength of associations between exposures and health outcomes, adjusting for potential confounders, and predicting the probability of an outcome given certain values of the independent variables. They can also be used to develop clinical prediction rules or scores that can aid in decision-making and patient care.

Human chromosome pair 18 consists of two rod-shaped structures present in the nucleus of each cell of the human body. Chromosomes are made up of DNA, protein, and RNA, and they carry genetic information that determines an individual's physical characteristics, biochemical processes, and susceptibility to disease.

Chromosome pair 18 is one of the 23 pairs of chromosomes that make up the human genome. Each member of chromosome pair 18 has a length of about 75 million base pairs and contains around 600 genes. Chromosome pair 18 is also known as the "smart chromosome" because it contains many genes involved in brain development, function, and cognition.

Abnormalities in chromosome pair 18 can lead to genetic disorders such as Edwards syndrome (trisomy 18), in which there is an extra copy of chromosome 18, or deletion of a portion of the chromosome, leading to various developmental and cognitive impairments.

Human chromosomes are thread-like structures that contain genetic material, composed of DNA and proteins, present in the nucleus of human cells. Each chromosome is a single, long DNA molecule that carries hundreds to thousands of genes.

Chromosomes 21, 22, and Y are three of the 23 pairs of human chromosomes. Here's what you need to know about each:

* Chromosome 21 is the smallest human autosomal chromosome, with a total length of about 47 million base pairs. It contains an estimated 200-300 genes and is associated with several genetic disorders, most notably Down syndrome, which occurs when there is an extra copy of this chromosome (trisomy 21).
* Chromosome 22 is the second smallest human autosomal chromosome, with a total length of about 50 million base pairs. It contains an estimated 500-600 genes and is associated with several genetic disorders, including DiGeorge syndrome and cat-eye syndrome.
* The Y chromosome is one of the two sex chromosomes (the other being the X chromosome) and is found only in males. It is much smaller than the X chromosome, with a total length of about 59 million base pairs and an estimated 70-200 genes. The Y chromosome determines maleness by carrying the gene for the testis-determining factor (TDF), which triggers male development in the embryo.

It's worth noting that while we have a standard set of 23 pairs of chromosomes, there can be variations and abnormalities in the number or structure of these chromosomes that can lead to genetic disorders.

"Marital status" is not a medical term, but it is often used in medical records and forms to indicate whether a person is single, married, divorced, widowed, or in a civil union. It is a social determinant of health that can have an impact on a person's access to healthcare, health behaviors, and health outcomes. For example, research has shown that people who are unmarried, divorced, or widowed may have worse health outcomes than those who are married. However, it is important to note that this relationship is complex and influenced by many other factors, including socioeconomic status, age, and overall health.

Karyotyping is a medical laboratory test used to study the chromosomes in a cell. It involves obtaining a sample of cells from a patient, usually from blood or bone marrow, and then staining the chromosomes so they can be easily seen under a microscope. The chromosomes are then arranged in pairs based on their size, shape, and other features to create a karyotype. This visual representation allows for the identification and analysis of any chromosomal abnormalities, such as extra or missing chromosomes, or structural changes like translocations or inversions. These abnormalities can provide important information about genetic disorders, diseases, and developmental problems.

The odds ratio (OR) is a statistical measure used in epidemiology and research to estimate the association between an exposure and an outcome. It represents the odds that an event will occur in one group versus the odds that it will occur in another group, assuming that all other factors are held constant.

In medical research, the odds ratio is often used to quantify the strength of the relationship between a risk factor (exposure) and a disease outcome. An OR of 1 indicates no association between the exposure and the outcome, while an OR greater than 1 suggests that there is a positive association between the two. Conversely, an OR less than 1 implies a negative association.

It's important to note that the odds ratio is not the same as the relative risk (RR), which compares the incidence rates of an outcome in two groups. While the OR can approximate the RR when the outcome is rare, they are not interchangeable and can lead to different conclusions about the association between an exposure and an outcome.

In medical terms, the "neck" is defined as the portion of the body that extends from the skull/head to the thorax or chest region. It contains 7 cervical vertebrae, muscles, nerves, blood vessels, lymphatic vessels, and glands (such as the thyroid gland). The neck is responsible for supporting the head, allowing its movement in various directions, and housing vital structures that enable functions like respiration and circulation.

"Prenatal exposure delayed effects" refer to the adverse health outcomes or symptoms that become apparent in an individual during their development or later in life, which are caused by exposure to certain environmental factors or substances while they were still in the womb. These effects may not be immediately observable at birth and can take weeks, months, years, or even decades to manifest. They can result from maternal exposure to various agents such as infectious diseases, medications, illicit drugs, tobacco smoke, alcohol, or environmental pollutants during pregnancy. The delayed effects can impact multiple organ systems and may include physical, cognitive, behavioral, and developmental abnormalities. It is important to note that the risk and severity of these effects can depend on several factors, including the timing, duration, and intensity of the exposure, as well as the individual's genetic susceptibility.

An oculocardiac reflex is a medical term that refers to a reflexive response that involves the eye and the heart. This reflex is elicited when there is pressure or traction applied to the eye or its surrounding structures, which can result in a decrease in heart rate.

The oculocardiac reflex is mediated by the ophthalmic division of the trigeminal nerve (cranial nerve V) and the vagus nerve (cranial nerve X). When the eye or its surrounding structures are stimulated, the impulses travel through the ophthalmic branch of the trigeminal nerve to the brainstem, where they synapse with neurons in the vagus nerve. The vagus nerve then carries these impulses to the sinoatrial node of the heart, which results in a decrease in heart rate.

The oculocardiac reflex is commonly seen during ophthalmic surgical procedures, particularly those that involve manipulation of the eye or its surrounding structures. It can also occur in response to other forms of stimulation, such as coughing, sneezing, or vomiting. In some cases, the oculocardiac reflex can lead to a significant decrease in heart rate, which may require medical intervention to prevent serious complications.

Socioeconomic factors are a range of interconnected conditions and influences that affect the opportunities and resources a person or group has to maintain and improve their health and well-being. These factors include:

1. Economic stability: This includes employment status, job security, income level, and poverty status. Lower income and lack of employment are associated with poorer health outcomes.
2. Education: Higher levels of education are generally associated with better health outcomes. Education can affect a person's ability to access and understand health information, as well as their ability to navigate the healthcare system.
3. Social and community context: This includes factors such as social support networks, discrimination, and community safety. Strong social supports and positive community connections are associated with better health outcomes, while discrimination and lack of safety can negatively impact health.
4. Healthcare access and quality: Access to affordable, high-quality healthcare is an important socioeconomic factor that can significantly impact a person's health. Factors such as insurance status, availability of providers, and cultural competency of healthcare systems can all affect healthcare access and quality.
5. Neighborhood and built environment: The physical conditions in which people live, work, and play can also impact their health. Factors such as housing quality, transportation options, availability of healthy foods, and exposure to environmental hazards can all influence health outcomes.

Socioeconomic factors are often interrelated and can have a cumulative effect on health outcomes. For example, someone who lives in a low-income neighborhood with limited access to healthy foods and safe parks may also face challenges related to employment, education, and healthcare access that further impact their health. Addressing socioeconomic factors is an important part of promoting health equity and reducing health disparities.

Retrospective studies, also known as retrospective research or looking back studies, are a type of observational study that examines data from the past to draw conclusions about possible causal relationships between risk factors and outcomes. In these studies, researchers analyze existing records, medical charts, or previously collected data to test a hypothesis or answer a specific research question.

Retrospective studies can be useful for generating hypotheses and identifying trends, but they have limitations compared to prospective studies, which follow participants forward in time from exposure to outcome. Retrospective studies are subject to biases such as recall bias, selection bias, and information bias, which can affect the validity of the results. Therefore, retrospective studies should be interpreted with caution and used primarily to generate hypotheses for further testing in prospective studies.

A case-control study is an observational research design used to identify risk factors or causes of a disease or health outcome. In this type of study, individuals with the disease or condition (cases) are compared with similar individuals who do not have the disease or condition (controls). The exposure history or other characteristics of interest are then compared between the two groups to determine if there is an association between the exposure and the disease.

Case-control studies are often used when it is not feasible or ethical to conduct a randomized controlled trial, as they can provide valuable insights into potential causes of diseases or health outcomes in a relatively short period of time and at a lower cost than other study designs. However, because case-control studies rely on retrospective data collection, they are subject to biases such as recall bias and selection bias, which can affect the validity of the results. Therefore, it is important to carefully design and conduct case-control studies to minimize these potential sources of bias.

The sex ratio is not a medical term per se, but it is a term used in demography and population health. The sex ratio is the ratio of males to females in a given population. It is typically expressed as the number of males for every 100 females. A sex ratio of 100 would indicate an equal number of males and females.

In the context of human populations, the sex ratio at birth is usually around 103-107 males per 100 females, reflecting a slightly higher likelihood of male births. However, due to biological factors such as higher male mortality rates in infancy and childhood, as well as social and behavioral factors, the sex ratio tends to equalize over time and can even shift in favor of women in older age groups.

It's worth noting that significant deviations from the expected sex ratio at birth or in a population can indicate underlying health issues or societal problems. For example, skewed sex ratios may be associated with gender discrimination, selective abortion of female fetuses, or exposure to environmental toxins that affect male reproductive health.

Breastfeeding is the process of providing nutrition to an infant or young child by feeding them breast milk directly from the mother's breast. It is also known as nursing. Breast milk is the natural food for newborns and infants, and it provides all the nutrients they need to grow and develop during the first six months of life.

Breastfeeding has many benefits for both the mother and the baby. For the baby, breast milk contains antibodies that help protect against infections and diseases, and it can also reduce the risk of sudden infant death syndrome (SIDS), allergies, and obesity. For the mother, breastfeeding can help her lose weight after pregnancy, reduce the risk of certain types of cancer, and promote bonding with her baby.

Breastfeeding is recommended exclusively for the first six months of an infant's life, and then continued along with appropriate complementary foods until the child is at least two years old or beyond. However, it is important to note that every mother and baby pair is unique, and what works best for one may not work as well for another. It is recommended that mothers consult with their healthcare provider to determine the best feeding plan for themselves and their baby.

Human chromosome pair 13 consists of two rod-shaped structures present in the nucleus of each cell in the human body. Each chromosome is made up of DNA tightly coiled around histone proteins, forming a complex structure called a chromatin.

Chromosomes carry genetic information in the form of genes, which are sequences of DNA that code for specific traits and functions. Human cells typically have 23 pairs of chromosomes, for a total of 46 chromosomes. Chromosome pair 13 is one of the autosomal pairs, meaning it is not a sex chromosome (X or Y).

Chromosome pair 13 contains several important genes that are associated with various genetic disorders, such as cri-du-chat syndrome and Phelan-McDermid syndrome. Cri-du-chat syndrome is caused by a deletion of the short arm of chromosome 13 (13p), resulting in distinctive cat-like crying sounds in infants, developmental delays, and intellectual disabilities. Phelan-McDermid syndrome is caused by a deletion or mutation of the terminal end of the long arm of chromosome 13 (13q), leading to developmental delays, intellectual disability, absent or delayed speech, and autistic behaviors.

It's important to note that while some genetic disorders are associated with specific chromosomal abnormalities, many factors can contribute to the development and expression of these conditions, including environmental influences and interactions between multiple genes.

"Maternal exposure" is a medical term that refers to the contact or interaction of a pregnant woman with various environmental factors, such as chemicals, radiation, infectious agents, or physical environments, which could potentially have an impact on the developing fetus. This exposure can occur through different routes, including inhalation, ingestion, dermal contact, or even transplacentally. The effects of maternal exposure on the fetus can vary widely depending on the type, duration, and intensity of the exposure, as well as the stage of pregnancy at which it occurs. It is important to monitor and minimize maternal exposure to potentially harmful substances or environments during pregnancy to ensure the best possible outcomes for both the mother and developing fetus.

Premature obstetric labor, also known as preterm labor, is defined as regular contractions leading to cervical changes that begin before 37 weeks of gestation. This condition can result in premature birth and potentially complications for the newborn, depending on how early the delivery occurs. It's important to note that premature labor requires medical attention and intervention to try to stop or delay it, if possible, to allow for further fetal development.

Pre-eclampsia is a pregnancy-related disorder, typically characterized by the onset of high blood pressure (hypertension) and damage to organs, such as the kidneys, after the 20th week of pregnancy. It is often accompanied by proteinuria, which is the presence of excess protein in the urine. Pre-eclampsia can lead to serious complications for both the mother and the baby if left untreated or unmanaged.

The exact causes of pre-eclampsia are not fully understood, but it is believed that placental issues, genetic factors, and immune system problems may contribute to its development. Risk factors include first-time pregnancies, history of pre-eclampsia in previous pregnancies, chronic hypertension, obesity, older age (35 or older), and assisted reproductive technology (ART) pregnancies.

Pre-eclampsia can progress to a more severe form called eclampsia, which is characterized by the onset of seizures. HELLP syndrome, another severe complication, involves hemolysis (breaking down of red blood cells), elevated liver enzymes, and low platelet count.

Early detection and management of pre-eclampsia are crucial to prevent severe complications. Regular prenatal care, including frequent blood pressure checks and urine tests, can help identify early signs of the condition. Treatment typically involves close monitoring, medication to lower blood pressure, corticosteroids to promote fetal lung maturity, and, in some cases, delivery of the baby if the mother's or baby's health is at risk.

Intracytoplasmic Sperm Injection (ICSI) is a specialized form of assisted reproductive technology (ART), specifically used in the context of in vitro fertilization (IVF). It involves the direct injection of a single sperm into the cytoplasm of a mature egg (oocyte) to facilitate fertilization. This technique is often used when there are issues with male infertility, such as low sperm count or poor sperm motility, to increase the chances of successful fertilization. The resulting embryos can then be transferred to the uterus in hopes of achieving a pregnancy.

The nasal bones are a pair of small, thin bones located in the upper part of the face, specifically in the middle of the nose. They articulate with each other at the nasal bridge and with the frontal bone above, the maxillae (upper jaw bones) on either side, and the septal cartilage inside the nose. The main function of the nasal bones is to form the bridge of the nose and protect the nasal cavity. Any damage to these bones can result in a fracture or broken nose.

Gestational diabetes is a type of diabetes that occurs during pregnancy. It is characterized by an increase in blood sugar levels that begins or is first recognized during pregnancy. The condition usually develops around the 24th week of gestation and is caused by the body's inability to produce enough insulin to meet the increased demands of pregnancy.

Gestational diabetes typically resolves after delivery, but women who have had gestational diabetes are at an increased risk of developing type 2 diabetes later in life. It is important for women with gestational diabetes to manage their blood sugar levels during pregnancy to reduce the risk of complications for both the mother and the baby.

Management of gestational diabetes may include lifestyle modifications such as dietary changes and exercise, as well as monitoring blood sugar levels and potentially using insulin or other medications to control blood sugar levels. Regular prenatal care is essential for women with gestational diabetes to ensure that their blood sugar levels are properly managed and to monitor the growth and development of the fetus.

Prospective studies, also known as longitudinal studies, are a type of cohort study in which data is collected forward in time, following a group of individuals who share a common characteristic or exposure over a period of time. The researchers clearly define the study population and exposure of interest at the beginning of the study and follow up with the participants to determine the outcomes that develop over time. This type of study design allows for the investigation of causal relationships between exposures and outcomes, as well as the identification of risk factors and the estimation of disease incidence rates. Prospective studies are particularly useful in epidemiology and medical research when studying diseases with long latency periods or rare outcomes.

Educational status refers to the level or stage of education that a person has reached. It can be used to describe an individual's educational background, achievements, and qualifications. Educational status can be categorized in various ways, including by level (e.g., elementary school, high school, college, graduate school), years of schooling completed, or type of degree earned (e.g., bachelor's, master's, doctoral).

In medical settings, educational status may be used as a demographic variable to describe the characteristics of a patient population or to identify potential disparities in health outcomes based on education level. Research has shown that higher levels of education are often associated with better health outcomes, including lower rates of chronic diseases and improved mental health. Therefore, understanding a patient's educational status can help healthcare providers tailor their care and education strategies to meet the unique needs and challenges of each individual.

Embryo transfer is a medical procedure that involves the transfer of an embryo, which is typically created through in vitro fertilization (IVF), into the uterus of a woman with the aim of establishing a pregnancy. The embryo may be created using the intended parent's own sperm and eggs or those from donors. After fertilization and early cell division, the resulting embryo is transferred into the uterus of the recipient mother through a thin catheter that is inserted through the cervix. This procedure is typically performed under ultrasound guidance to ensure proper placement of the embryo. Embryo transfer is a key step in assisted reproductive technology (ART) and is often used as a treatment for infertility.

Regression analysis is a statistical technique used in medicine, as well as in other fields, to examine the relationship between one or more independent variables (predictors) and a dependent variable (outcome). It allows for the estimation of the average change in the outcome variable associated with a one-unit change in an independent variable, while controlling for the effects of other independent variables. This technique is often used to identify risk factors for diseases or to evaluate the effectiveness of medical interventions. In medical research, regression analysis can be used to adjust for potential confounding variables and to quantify the relationship between exposures and health outcomes. It can also be used in predictive modeling to estimate the probability of a particular outcome based on multiple predictors.

In the context of medicine, risk is the probability or likelihood of an adverse health effect or the occurrence of a negative event related to treatment or exposure to certain hazards. It is usually expressed as a ratio or percentage and can be influenced by various factors such as age, gender, lifestyle, genetics, and environmental conditions. Risk assessment involves identifying, quantifying, and prioritizing risks to make informed decisions about prevention, mitigation, or treatment strategies.

The medical definition of "Habitual Abortion" refers to a woman who has three or more consecutive pregnancies that end in spontaneous miscarriages before 20 weeks of gestation. The cause of habitual abortions can be difficult to determine and may involve genetic, anatomical, hormonal, or immune system factors. Treatment is often aimed at addressing any underlying issues that may be contributing to the recurrent miscarriages. It's important to note that the terminology has changed over time and the term "recurrent pregnancy loss" is now more commonly used in place of "habitual abortion".

Gravidity is a medical term that refers to the number of times a woman has been pregnant, regardless of the outcome of the pregnancies. It's a way to quantify a woman's childbearing experience and is often used in obstetrics and gynecology to assess potential risks and complications during pregnancy and childbirth.

For example, a woman who has been pregnant once before would have a gravidity of 1, while a woman who has been pregnant twice would have a gravidity of 2. This term is distinct from parity, which refers to the number of pregnancies that have reached a viable gestational age and resulted in a live birth.

I'm sorry for any confusion, but "Norway" is not a medical term or concept. It is a country in Northern Europe, known officially as the Kingdom of Norway. If you have any questions about medical topics or definitions, I would be happy to help!

Fetal macrosomia is a medical condition where the fetus in the womb is significantly larger than normal. While there is no consensus on an exact weight that defines macrosomia, it is generally defined as a fetus with an estimated weight of 4,000 grams (8 pounds 13 ounces) or more at birth.

Fetal macrosomia can be caused by several factors, including maternal diabetes, post-term pregnancy, excessive weight gain during pregnancy, and prior history of macrosomic infants. Macrosomic infants are at an increased risk for complications during labor and delivery, such as shoulder dystocia, birth injuries, and hypoglycemia.

It is important for healthcare providers to monitor fetal growth carefully during pregnancy, particularly in women who have risk factors for macrosomia. Regular prenatal care, including ultrasound measurements of the fetus, can help identify cases of fetal macrosomia and allow for appropriate management and delivery planning.

"Age factors" refer to the effects, changes, or differences that age can have on various aspects of health, disease, and medical care. These factors can encompass a wide range of issues, including:

1. Physiological changes: As people age, their bodies undergo numerous physical changes that can affect how they respond to medications, illnesses, and medical procedures. For example, older adults may be more sensitive to certain drugs or have weaker immune systems, making them more susceptible to infections.
2. Chronic conditions: Age is a significant risk factor for many chronic diseases, such as heart disease, diabetes, cancer, and arthritis. As a result, age-related medical issues are common and can impact treatment decisions and outcomes.
3. Cognitive decline: Aging can also lead to cognitive changes, including memory loss and decreased decision-making abilities. These changes can affect a person's ability to understand and comply with medical instructions, leading to potential complications in their care.
4. Functional limitations: Older adults may experience physical limitations that impact their mobility, strength, and balance, increasing the risk of falls and other injuries. These limitations can also make it more challenging for them to perform daily activities, such as bathing, dressing, or cooking.
5. Social determinants: Age-related factors, such as social isolation, poverty, and lack of access to transportation, can impact a person's ability to obtain necessary medical care and affect their overall health outcomes.

Understanding age factors is critical for healthcare providers to deliver high-quality, patient-centered care that addresses the unique needs and challenges of older adults. By taking these factors into account, healthcare providers can develop personalized treatment plans that consider a person's age, physical condition, cognitive abilities, and social circumstances.

I'm sorry for any confusion, but "Sicily" is not a medical term. It is actually a large island located in the Mediterranean Sea, south of the Italian Peninsula, and it is one of the five autonomous regions of Italy. If you have any questions about medical terminology or health-related topics, I would be happy to help!

The third trimester of pregnancy is the final stage of pregnancy that lasts from week 29 until birth, which typically occurs around the 40th week. During this period, the fetus continues to grow and mature, gaining weight rapidly. The mother's body also prepares for childbirth by dilating the cervix and producing milk in preparation for breastfeeding. Regular prenatal care is crucial during this time to monitor the health of both the mother and the developing fetus, as well as to prepare for delivery.

Twin pregnancy refers to a type of multiple pregnancy where a woman is carrying two fetuses simultaneously. There are two types of twin pregnancies: monozygotic (identical) and dizygotic (fraternal). Monoygotic twins occur when a single fertilized egg (zygote) splits and develops into two separate embryos, resulting in identical twins who share the same genetic material. Dizygotic twins, on the other hand, result from the fertilization of two separate eggs by two different sperm cells, leading to non-identical twins who have their own unique genetic material.

Twin pregnancies are associated with higher risks of complications compared to singleton pregnancies, including preterm labor, low birth weight, gestational diabetes, and preeclampsia. Close monitoring by healthcare providers is essential to ensure the best possible outcomes for both the mother and the twins.

Medical definitions of "Multiple Birth Offspring" refer to two or more children born to the same mother during one single pregnancy and childbirth. The most common forms of multiple birth offspring are twins (two babies), triplets (three babies), quadruplets (four babies), and so on.

The occurrence of multiple birth offspring is influenced by several factors, including genetics, maternal age, the use of fertility treatments, and other medical conditions. Multiple birth offspring may be identical (monozygotic) or fraternal (dizygotic), depending on whether they developed from a single fertilized egg or from separate eggs.

Multiple birth offspring often face unique health challenges, such as preterm birth, low birth weight, and developmental delays, due to the limited space and resources available in the womb. As a result, they may require specialized medical care and attention both during and after pregnancy.

I'm sorry for any confusion, but "social class" is not a term that has a medical definition. It is a sociological concept that refers to the grouping of individuals in a society based on their shared economic and social positions. This can include factors such as income, education, occupation, and wealth.

However, social class can have an impact on health outcomes and access to healthcare. For example, people in lower socioeconomic groups are more likely to experience chronic diseases, mental health disorders, and have limited access to quality healthcare services compared to those in higher socioeconomic groups. This relationship is often referred to as the "social determinants of health."

Pregnancy-induced hypertension (PIH), also known as gestational hypertension, is a condition characterized by the new onset of high blood pressure (≥140 mm Hg systolic or ≥90 mm Hg diastolic) after 20 weeks of pregnancy in a woman who was normotensive before. It can sometimes progress to more severe conditions like preeclampsia and eclampsia, which are associated with damage to other organ systems such as the liver and kidneys.

PIH is typically classified into two types:

1. Gestational hypertension: This is when a woman develops high blood pressure after 20 weeks of pregnancy without any protein in the urine or evidence of damage to other organ systems. Women with gestational hypertension are at increased risk for preeclampsia and may require closer monitoring.

2. Preeclampsia: This is a more severe form of PIH, characterized by high blood pressure and proteinuria (≥0.3 g in a 24-hour urine collection) after 20 weeks of pregnancy. Preeclampsia can also involve damage to other organ systems, such as the liver, kidneys, or brain, and may progress to eclampsia, a life-threatening condition characterized by seizures.

The exact causes of PIH are not fully understood, but it is thought to be related to problems with the development and function of the blood vessels that supply the placenta. Risk factors for developing PIH include first-time pregnancies, obesity, older age, a history of chronic hypertension or kidney disease, and carrying multiples (twins, triplets, etc.).

Treatment for PIH depends on the severity of the condition and the gestational age of the pregnancy. In mild cases, close monitoring of blood pressure, urine protein levels, and fetal growth may be sufficient. More severe cases may require medication to lower blood pressure, corticosteroids to promote fetal lung maturity, or early delivery of the baby to prevent further complications.

I'm not sure I understand your question. "Denmark" is a country located in Northern Europe, and it is not a medical term or concept. It is the southernmost of the Nordic countries, and it consists of the Jutland peninsula and several islands in the Baltic Sea. The capital city of Denmark is Copenhagen.

If you are looking for information about a medical condition that may be associated with Denmark, could you please provide more context or clarify your question? I would be happy to help you with more specific information if I can.

Fetal growth retardation, also known as intrauterine growth restriction (IUGR), is a condition in which a fetus fails to grow at the expected rate during pregnancy. This can be caused by various factors such as maternal health problems, placental insufficiency, chromosomal abnormalities, and genetic disorders. The fetus may be smaller than expected for its gestational age, have reduced movement, and may be at risk for complications during labor and delivery. It is important to monitor fetal growth and development closely throughout pregnancy to detect any potential issues early on and provide appropriate medical interventions.

Estriol is a type of estrogen, which is a female sex hormone. It is produced in the placenta during pregnancy and is used as a marker for fetal growth and development. Estriol levels can be measured in the mother's urine or blood to assess fetal well-being during pregnancy. Additionally, synthetic forms of estriol are sometimes used in hormone replacement therapy to treat symptoms of menopause.

Meiosis is a type of cell division that results in the formation of four daughter cells, each with half the number of chromosomes as the parent cell. It is a key process in sexual reproduction, where it generates gametes or sex cells (sperm and eggs).

The process of meiosis involves one round of DNA replication followed by two successive nuclear divisions, meiosis I and meiosis II. In meiosis I, homologous chromosomes pair, form chiasma and exchange genetic material through crossing over, then separate from each other. In meiosis II, sister chromatids separate, leading to the formation of four haploid cells. This process ensures genetic diversity in offspring by shuffling and recombining genetic information during the formation of gametes.

Perinatal care refers to the health care provided to pregnant individuals, fetuses, and newborn infants during the time immediately before and after birth. This period is defined as beginning at approximately 20 weeks of gestation and ending 4 weeks after birth. Perinatal care includes preventative measures, medical and supportive services, and treatment for complications during pregnancy, childbirth, and in the newborn period. It encompasses a wide range of services including prenatal care, labor and delivery management, postpartum care, and neonatal care. The goal of perinatal care is to ensure the best possible outcomes for both the mother and the baby by preventing, diagnosing, and treating any potential health issues that may arise during this critical period.

The Apgar score is a quick assessment of the physical condition of a newborn infant, assessed by measuring heart rate, respiratory effort, muscle tone, reflex irritability, and skin color. It is named after Virginia Apgar, an American anesthesiologist who developed it in 1952. The score is usually given at one minute and five minutes after birth, with a possible range of 0 to 10. Scores of 7 and above are considered normal, while scores of 4-6 indicate moderate distress, and scores below 4 indicate severe distress. The Apgar score can provide important information for making decisions about the need for resuscitation or other medical interventions after birth.

Prevalence, in medical terms, refers to the total number of people in a given population who have a particular disease or condition at a specific point in time, or over a specified period. It is typically expressed as a percentage or a ratio of the number of cases to the size of the population. Prevalence differs from incidence, which measures the number of new cases that develop during a certain period.

Infertility is a reproductive health disorder defined as the failure to achieve a clinical pregnancy after 12 months or more of regular, unprotected sexual intercourse or due to an impairment of a person's capacity to reproduce either as an individual or with their partner. It can be caused by various factors in both men and women, including hormonal imbalances, structural abnormalities, genetic issues, infections, age, lifestyle factors, and others. Infertility can have significant emotional and psychological impacts on individuals and couples experiencing it, and medical intervention may be necessary to help them conceive.

Induced abortion is a medical procedure that intentionally terminates a pregnancy before the fetus can survive outside the womb. It can be performed either surgically or medically through the use of medications. The timing of an induced abortion is typically based on the gestational age of the pregnancy, with different methods used at different stages.

The most common surgical procedure for induced abortion is vacuum aspiration, which is usually performed during the first trimester (up to 12-13 weeks of gestation). This procedure involves dilating the cervix and using a vacuum device to remove the pregnancy tissue from the uterus. Other surgical procedures, such as dilation and evacuation (D&E), may be used in later stages of pregnancy.

Medical abortion involves the use of medications to induce the termination of a pregnancy. The most common regimen involves the use of two drugs: mifepristone and misoprostol. Mifepristone works by blocking the action of progesterone, a hormone necessary for maintaining pregnancy. Misoprostol causes the uterus to contract and expel the pregnancy tissue. This method is typically used during the first 10 weeks of gestation.

Induced abortion is a safe and common medical procedure, with low rates of complications when performed by trained healthcare providers in appropriate settings. Access to induced abortion varies widely around the world, with some countries restricting or prohibiting the practice entirely.

Separase is not a medical term itself, but it is a biological term used in the field of cell biology and genetics. Separase is an enzyme that plays a crucial role in the separation of chromosomes during cell division (mitosis and meiosis).

In more detail, separase is a protease enzyme that contributes to the breakdown of cohesin complexes, which are protein structures that hold sister chromatids together after DNA replication. Separase's function is essential for the proper separation of chromosomes during anaphase, the stage of mitosis where sister chromatids are pulled apart and moved to opposite poles of the cell.

While not a medical term per se, understanding separase and its role in cell division can help researchers better understand certain genetic disorders or diseases that may be caused by errors in cell division.

In medical terms, triplets are a type of multiple pregnancy, where three offsprings (fetuses) develop simultaneously in the uterus of a single pregnant woman. This occurs when a woman releases more than one egg during ovulation, and all three eggs get fertilized by separate sperm cells. Triplets can also occur through the use of assisted reproductive technologies such as in vitro fertilization (IVF) where multiple embryos are transferred into the uterus.

Triplet pregnancies carry a higher risk of complications for both the mother and the offsprings compared to singleton or twin pregnancies, including preterm labor, low birth weight, and developmental issues. As such, they often require close monitoring and specialized care throughout the pregnancy.

'Pregnant women' refers to female individuals who have conceived and are in the process of carrying a developing fetus inside their womb (uterus) until childbirth. This state is typically marked by various physiological changes, including hormonal fluctuations, weight gain, and growth of the uterus and breasts, among others. Pregnancy usually lasts for about 40 weeks, starting from the first day of the woman's last menstrual period (LMP) and is divided into three trimesters. Each trimester is characterized by different developmental milestones in the fetus. Regular prenatal care is essential to monitor the health and wellbeing of both the mother and the developing fetus, and to address any potential complications that may arise during pregnancy.

Parturition is the process of giving birth, or the act of delivering newborn offspring. In medical terms, it refers to the expulsion of the products of conception (such as the fetus, placenta, and membranes) from the uterus of a pregnant woman during childbirth. This process is regulated by hormonal changes and involves complex interactions between the mother's body and the developing fetus. Parturition typically occurs after a full-term pregnancy, which is approximately 40 weeks in humans.

Induced labor refers to the initiation of labor before it begins spontaneously, which is usually achieved through medical intervention. This process is initiated when there is a medically indicated reason to deliver the baby, such as maternal or fetal compromise, prolonged pregnancy, or reduced fetal movement. The most common methods used to induce labor include membrane stripping, prostaglandin administration, and oxytocin infusion. It's important to note that induced labor carries certain risks, including a higher chance of uterine hyperstimulation, infection, and the need for assisted vaginal delivery or cesarean section. Therefore, it should only be performed under the close supervision of a healthcare provider in a clinical setting.

A premature infant is a baby born before 37 weeks of gestation. They may face various health challenges because their organs are not fully developed. The earlier a baby is born, the higher the risk of complications. Prematurity can lead to short-term and long-term health issues, such as respiratory distress syndrome, jaundice, anemia, infections, hearing problems, vision problems, developmental delays, and cerebral palsy. Intensive medical care and support are often necessary for premature infants to ensure their survival and optimal growth and development.

Smoking is not a medical condition, but it's a significant health risk behavior. Here is the definition from a public health perspective:

Smoking is the act of inhaling and exhaling the smoke of burning tobacco that is commonly consumed through cigarettes, pipes, and cigars. The smoke contains over 7,000 chemicals, including nicotine, tar, carbon monoxide, and numerous toxic and carcinogenic substances. These toxins contribute to a wide range of diseases and health conditions, such as lung cancer, heart disease, stroke, chronic obstructive pulmonary disease (COPD), and various other cancers, as well as adverse reproductive outcomes and negative impacts on the developing fetus during pregnancy. Smoking is highly addictive due to the nicotine content, which makes quitting smoking a significant challenge for many individuals.

Fertility is the natural ability to conceive or to cause conception of offspring. In humans, it is the capacity of a woman and a man to reproduce through sexual reproduction. For women, fertility usually takes place during their reproductive years, which is from adolescence until menopause. A woman's fertility depends on various factors including her age, overall health, and the health of her reproductive system.

For men, fertility can be affected by a variety of factors such as age, genetics, general health, sexual function, and environmental factors that may affect sperm production or quality. Factors that can negatively impact male fertility include exposure to certain chemicals, radiation, smoking, alcohol consumption, drug use, and sexually transmitted infections (STIs).

Infertility is a common medical condition affecting about 10-15% of couples trying to conceive. Infertility can be primary or secondary. Primary infertility refers to the inability to conceive after one year of unprotected sexual intercourse, while secondary infertility refers to the inability to conceive following a previous pregnancy.

Infertility can be treated with various medical and surgical interventions depending on the underlying cause. These may include medications to stimulate ovulation, intrauterine insemination (IUI), in vitro fertilization (IVF), or surgery to correct anatomical abnormalities.

I'm sorry for any confusion, but "Sweden" is not a medical term. It is a country located in northern Europe. If you have any questions about medical terminology or concepts, I would be happy to help answer those!

I'm sorry for any confusion, but "New York" is not a medical term or concept. New York refers to a state in the United States, as well as its largest city. If you have any questions about medical terminology or concepts, I would be happy to help with those!

The isoelectric point (pI) is a term used in biochemistry and molecular biology to describe the pH at which a molecule, such as a protein or peptide, carries no net electrical charge. At this pH, the positive and negative charges on the molecule are equal and balanced. The pI of a protein can be calculated based on its amino acid sequence and is an important property that affects its behavior in various chemical and biological environments. Proteins with different pIs may have different solubilities, stabilities, and interactions with other molecules, which can impact their function and role in the body.

Anencephaly is a serious birth defect that affects the neural tube, which is the structure that develops into the brain and spinal cord. In anencephaly, the neural tube fails to close properly during fetal development, resulting in the absence of a major portion of the brain, skull, and scalp.

Anencephaly is typically diagnosed through prenatal ultrasound or other imaging tests. Unfortunately, it is a fatal condition, and most babies with anencephaly do not survive birth or live for more than a few hours or days after birth.

The exact cause of anencephaly is not fully understood, but it is believed to be related to genetic factors as well as environmental influences such as folic acid deficiency and exposure to certain medications or chemicals during pregnancy. Pregnant women are often advised to take folic acid supplements to reduce the risk of neural tube defects, including anencephaly.

Sex chromosome aberrations refer to structural and numerical abnormalities in the sex chromosomes, which are typically represented as X and Y chromosomes in humans. These aberrations can result in variations in the number of sex chromosomes, such as Klinefelter syndrome (47,XXY), Turner syndrome (45,X), and Jacobs/XYY syndrome (47,XYY). They can also include structural changes, such as deletions, duplications, or translocations of sex chromosome material.

Sex chromosome aberrations may lead to a range of phenotypic effects, including differences in physical characteristics, cognitive development, fertility, and susceptibility to certain health conditions. The manifestation and severity of these impacts can vary widely depending on the specific type and extent of the aberration, as well as individual genetic factors and environmental influences.

It is important to note that while sex chromosome aberrations may pose challenges and require medical management, they do not inherently define or limit a person's potential, identity, or worth. Comprehensive care, support, and education can help individuals with sex chromosome aberrations lead fulfilling lives and reach their full potential.

Fetal heart rate (FHR) is the number of times a fetus's heart beats in one minute. It is measured through the use of a fetoscope, Doppler ultrasound device, or cardiotocograph (CTG). A normal FHR ranges from 120 to 160 beats per minute (bpm), although it can vary throughout pregnancy and is usually faster than an adult's heart rate. Changes in the FHR pattern may indicate fetal distress, hypoxia, or other conditions that require medical attention. Regular monitoring of FHR during pregnancy, labor, and delivery helps healthcare providers assess fetal well-being and ensure a safe outcome for both the mother and the baby.

'Pregnancy in Diabetics' refers to the condition where an individual with pre-existing diabetes mellitus becomes pregnant. This can be further categorized into two types:

1. Pre-gestational diabetes: This is when a woman is diagnosed with diabetes before she becomes pregnant. It includes both Type 1 and Type 2 diabetes. Proper control of blood sugar levels prior to conception and during pregnancy is crucial to reduce the risk of complications for both the mother and the baby.

2. Gestational diabetes: This is when a woman develops high blood sugar levels during pregnancy, typically in the second or third trimester. While it usually resolves after delivery, women with gestational diabetes have a higher risk of developing Type 2 diabetes later in life. Proper management of gestational diabetes is essential to ensure a healthy pregnancy and reduce the risk of complications for both the mother and the baby.

"Family characteristics" is a broad term that can refer to various attributes, dynamics, and structures of a family unit. These characteristics can include:

1. Family structure: This refers to the composition of the family, such as whether it is a nuclear family (two parents and their children), single-parent family, extended family, blended family, or same-sex parent family.
2. Family roles: The responsibilities and expectations assigned to each family member, such as caregiver, provider, or decision-maker.
3. Communication patterns: How family members communicate with one another, including frequency, tone, and level of openness.
4. Problem-solving styles: How the family approaches and resolves conflicts and challenges.
5. Cultural and religious practices: The values, traditions, and beliefs that shape the family's identity and worldview.
6. Family functioning: The overall health and effectiveness of the family system, including its ability to adapt to change and support individual members' needs.
7. Attachment styles: The quality and nature of the emotional bonds between family members, which can impact attachment security and relationships throughout life.
8. Parenting style: The approach that parents take in raising their children, such as authoritative, authoritarian, permissive, or uninvolved.
9. Family history: Past experiences and events that have shaped the family's development and dynamics.
10. Genetic factors: Inherited traits and predispositions that can influence family members' health, behavior, and personality.

Understanding family characteristics is essential in fields such as medicine, psychology, social work, and counseling, as these factors can significantly impact individual and family well-being.

Maternal mortality is defined by the World Health Organization (WHO) as "the death of a woman while pregnant or within 42 days of termination of pregnancy, irrespective of the duration and site of the pregnancy, from any cause related to or aggravated by the pregnancy or its management but not from accidental or incidental causes."

This definition highlights that maternal mortality is a preventable death that occurs during pregnancy, childbirth, or in the postpartum period, and it can be caused by various factors related to or worsened by the pregnancy or its management. The WHO also collects data on maternal deaths due to direct obstetric causes (such as hemorrhage, hypertensive disorders, sepsis, and unsafe abortion) and indirect causes (such as malaria, anemia, and HIV/AIDS).

Maternal mortality is a significant public health issue worldwide, particularly in low- and middle-income countries. Reducing maternal mortality is one of the Sustainable Development Goals (SDGs) set by the United Nations, with a target to reduce the global maternal mortality ratio to less than 70 per 100,000 live births by 2030.

Mosaicism, in the context of genetics and medicine, refers to the presence of two or more cell lines with different genetic compositions in an individual who has developed from a single fertilized egg. This means that some cells have one genetic makeup, while others have a different genetic makeup. This condition can occur due to various reasons such as errors during cell division after fertilization.

Mosaicism can involve chromosomes (where whole or parts of chromosomes are present in some cells but not in others) or it can involve single genes (where a particular gene is present in one form in some cells and a different form in others). The symptoms and severity of mosaicism can vary widely, depending on the type and location of the genetic difference and the proportion of cells that are affected. Some individuals with mosaicism may not experience any noticeable effects, while others may have significant health problems.

Fetal mortality refers to the death of a fetus after reaching viability, typically defined as 20 weeks of gestation or greater. The term "stillbirth" is often used interchangeably with fetal mortality and is generally defined as the birth of a baby who has died in the womb after 20 weeks of pregnancy.

Fetal mortality can be caused by a variety of factors, including chromosomal abnormalities, maternal health conditions, placental problems, infections, and complications during labor and delivery. In some cases, the cause of fetal mortality may remain unknown.

The rate of fetal mortality is an important public health indicator and is closely monitored by healthcare providers and researchers. Reducing fetal mortality requires a multifaceted approach that includes prenatal care, identification and management of risk factors, and access to high-quality obstetric care.

'Infant welfare' is not a medical term per se, but it is a term used to describe the overall health and well-being of infants. It encompasses various aspects of infant care, including physical, mental, emotional, and social development. Infant welfare aims to promote healthy growth and development, prevent illness and injury, and provide early intervention and treatment for any health issues that may arise.

Infant welfare programs often include services such as well-child visits, immunizations, developmental screenings, nutrition counseling, and parent education on topics such as safe sleep practices, feeding, and child safety. These programs are typically provided through healthcare systems, public health departments, and community organizations. The ultimate goal of infant welfare is to ensure that infants have the best possible start in life and are equipped with the necessary foundation for a healthy and successful future.

Human chromosomes 13-15 are part of a set of 23 pairs of chromosomes found in the cells of the human body. Chromosomes are thread-like structures that contain genetic material, or DNA, that is inherited from each parent. They are responsible for the development and function of all the body's organs and systems.

Chromosome 13 is a medium-sized chromosome and contains an estimated 114 million base pairs of DNA. It is associated with several genetic disorders, including cri du chat syndrome, which is caused by a deletion on the short arm of the chromosome. Chromosome 13 also contains several important genes, such as those involved in the production of enzymes and proteins that help regulate growth and development.

Chromosome 14 is a medium-sized chromosome and contains an estimated 107 million base pairs of DNA. It is known to contain many genes that are important for the normal functioning of the brain and nervous system, as well as genes involved in the production of immune system proteins. Chromosome 14 is also associated with a number of genetic disorders, including Wolf-Hirschhorn syndrome, which is caused by a deletion on the short arm of the chromosome.

Chromosome 15 is a medium-sized chromosome and contains an estimated 102 million base pairs of DNA. It is associated with several genetic disorders, including Prader-Willi syndrome and Angelman syndrome, which are caused by abnormalities in the expression of genes on the chromosome. Chromosome 15 also contains important genes involved in the regulation of growth and development, as well as genes that play a role in the production of neurotransmitters, the chemical messengers of the brain.

It is worth noting that while chromosomes 13-15 are important for normal human development and function, abnormalities in these chromosomes can lead to a variety of genetic disorders and developmental issues.

An oocyte, also known as an egg cell or female gamete, is a large specialized cell found in the ovary of female organisms. It contains half the number of chromosomes as a normal diploid cell, as it is the product of meiotic division. Oocytes are surrounded by follicle cells and are responsible for the production of female offspring upon fertilization with sperm. The term "oocyte" specifically refers to the immature egg cell before it reaches full maturity and is ready for fertilization, at which point it is referred to as an ovum or egg.

Maternal welfare is not a term that has a specific medical definition. However, in a general sense, it refers to the physical, mental, and social well-being of a woman during pregnancy, childbirth, and the postpartum period. It encompasses various factors such as access to quality healthcare services, nutrition, emotional support, and a safe and healthy environment.

Maternal welfare is an essential component of maternal health, which aims to ensure that women have a positive and safe pregnancy and childbirth experience, free from complications and harm. It involves addressing issues related to maternal mortality and morbidity, prenatal care, family planning, and reproductive rights.

Promoting maternal welfare requires a multidisciplinary approach that includes healthcare providers, policymakers, community leaders, and families working together to ensure that women have access to the resources and support they need to maintain their health and well-being during pregnancy and beyond.

The term "European Continental Ancestry Group" is a medical/ethnic classification that refers to individuals who trace their genetic ancestry to the continent of Europe. This group includes people from various ethnic backgrounds and nationalities, such as Northern, Southern, Eastern, and Western European descent. It is often used in research and medical settings for population studies or to identify genetic patterns and predispositions to certain diseases that may be more common in specific ancestral groups. However, it's important to note that this classification can oversimplify the complex genetic diversity within and between populations, and should be used with caution.

Female infertility is a condition characterized by the inability to conceive after 12 months or more of regular, unprotected sexual intercourse or the inability to carry a pregnancy to a live birth. The causes of female infertility can be multifactorial and may include issues with ovulation, damage to the fallopian tubes or uterus, endometriosis, hormonal imbalances, age-related factors, and other medical conditions.

Some common causes of female infertility include:

1. Ovulation disorders: Conditions such as polycystic ovary syndrome (PCOS), thyroid disorders, premature ovarian failure, and hyperprolactinemia can affect ovulation and lead to infertility.
2. Damage to the fallopian tubes: Pelvic inflammatory disease, endometriosis, or previous surgeries can cause scarring and blockages in the fallopian tubes, preventing the egg and sperm from meeting.
3. Uterine abnormalities: Structural issues with the uterus, such as fibroids, polyps, or congenital defects, can interfere with implantation and pregnancy.
4. Age-related factors: As women age, their fertility declines due to a decrease in the number and quality of eggs.
5. Other medical conditions: Certain medical conditions, such as diabetes, celiac disease, and autoimmune disorders, can contribute to infertility.

In some cases, female infertility can be treated with medications, surgery, or assisted reproductive technologies (ART) like in vitro fertilization (IVF). A thorough evaluation by a healthcare professional is necessary to determine the underlying cause and develop an appropriate treatment plan.

In epidemiology, the incidence of a disease is defined as the number of new cases of that disease within a specific population over a certain period of time. It is typically expressed as a rate, with the number of new cases in the numerator and the size of the population at risk in the denominator. Incidence provides information about the risk of developing a disease during a given time period and can be used to compare disease rates between different populations or to monitor trends in disease occurrence over time.

A "term birth" is a medical term that refers to a delivery or pregnancy that has reached 37 weeks or more. It is the normal length of a full-term pregnancy and is considered a healthy and low-risk period for childbirth. Babies born at term have the best chance of being healthy and not experiencing any significant medical issues, compared to those born preterm (before 37 weeks) or postterm (after 42 weeks). The different types of term births are:

* Early Term: Between 37 weeks and 38 weeks, 6 days.
* Full Term: Between 39 weeks and 40 weeks, 6 days.
* Late Term: Between 41 weeks and 41 weeks, 6 days.
* Postterm: 42 weeks or later.

It is important to note that while a term birth is generally considered low-risk, there can still be variations in the health of babies born at different points within this range. For example, research has shown that babies born at 39 weeks have better outcomes than those born at 37 or 38 weeks. Therefore, it is always best to consult with a healthcare provider for individualized guidance and recommendations regarding pregnancy and childbirth.

Maternal behavior refers to the nurturing and protective behaviors exhibited by a female animal towards its offspring. In humans, this term is often used to describe the natural instincts and actions of a woman during pregnancy, childbirth, and early child-rearing. It encompasses a broad range of activities such as feeding, grooming, protecting, and teaching the young.

In the context of medical and psychological research, maternal behavior is often studied to understand the factors that influence its development, expression, and outcomes for both the mother and offspring. Factors that can affect maternal behavior include hormonal changes during pregnancy and childbirth, as well as social, cultural, and environmental influences.

Abnormal or atypical maternal behavior may indicate underlying mental health issues, such as postpartum depression or anxiety, and can have negative consequences for both the mother and the child's development and well-being. Therefore, it is important to monitor and support healthy maternal behaviors in new mothers to promote positive outcomes for both parties.

I'm sorry for any confusion, but "England" is not a medical term or concept. It is one of the four constituent countries that make up the United Kingdom, along with Wales, Scotland, and Northern Ireland. England is located in the southern part of Great Britain, which is the largest island of the British Isles.

If you have any questions related to medicine or healthcare, I would be happy to try to help answer them for you!

I'm sorry for any confusion, but "Nepal" is not a medical term. It is a country located in South Asia, between China and India. If you have any questions about medical terminology or health-related topics, I would be happy to try and help answer those for you.

In medical or legal terms, "illegitimacy" refers to the status of a child who is born to parents who are not married to each other. This concept is more commonly used in sociology and law rather than medicine. In some societies and historical periods, illegitimate children may have faced social stigma and discrimination, but this is less common in modern times. It's important to note that the concept of illegitimacy has been largely abandoned in many legal systems, and children are now recognized as having equal rights and status regardless of their parents' marital status.

"Adult children" is a term used to describe individuals who are typically adults in age, but who still have developmental or psychological dependencies on their parents or caregivers. This term is often used in the context of adult children of alcoholics or other dysfunctional families, where the adult child may exhibit behaviors such as:

* Difficulty setting boundaries
* Low self-esteem
* Fear of abandonment
* Difficulty with intimacy and commitment
* A tendency to assume responsibility for others' feelings and actions

These patterns often stem from childhood experiences in which the adult child took on a caretaking role or felt responsible for their parents' emotions. While "adult children" is not a formal medical term, it is widely used in psychology and social work to describe this population.

Obstetrical extraction refers to a medical procedure in obstetrics, where a fetus or a dead fetus is removed from the uterus through surgical means. This is typically performed when a vaginal delivery is not possible or safe due to various reasons such as obstructed labor, maternal or fetal distress, or prolonged pregnancy. The procedure may involve dilation and evacuation (D&E) or instrumental delivery using forceps or vacuum extractor. It is usually done under anesthesia in a hospital setting.

"Body height" is a measure of the vertical length of a person's body from the top of their head to the bottom of their feet. It is typically measured in units such as centimeters (cm) or inches (in). In medical settings, body height is often used as a basic anthropometric measurement to assess overall health status, growth and development, nutritional status, and aging-related changes.

There are different methods for measuring body height, but the most common one involves having the person stand upright against a vertical surface (such as a wall or a stadiometer) with their heels, buttocks, shoulders, and head touching the surface. The measurement is taken at the point where the top of the person's head meets the surface.

Body height can be influenced by various factors, including genetics, nutrition, health status, and environmental conditions. Changes in body height over time can provide important insights into a person's health trajectory and potential health risks. For example, a significant decrease in body height may indicate bone loss or spinal compression, while a rapid increase in height during childhood or adolescence may suggest optimal growth and development.

A fetus is the developing offspring in a mammal, from the end of the embryonic period (approximately 8 weeks after fertilization in humans) until birth. In humans, the fetal stage of development starts from the eleventh week of pregnancy and continues until childbirth, which is termed as full-term pregnancy at around 37 to 40 weeks of gestation. During this time, the organ systems become fully developed and the body grows in size. The fetus is surrounded by the amniotic fluid within the amniotic sac and is connected to the placenta via the umbilical cord, through which it receives nutrients and oxygen from the mother. Regular prenatal care is essential during this period to monitor the growth and development of the fetus and ensure a healthy pregnancy and delivery.

"Drug-induced abnormalities" refer to physical or physiological changes that occur as a result of taking medication or drugs. These abnormalities can affect various organs and systems in the body and can range from minor symptoms, such as nausea or dizziness, to more serious conditions, such as liver damage or heart rhythm disturbances.

Drug-induced abnormalities can occur for several reasons, including:

1. Direct toxicity: Some drugs can directly damage cells and tissues in the body, leading to abnormalities.
2. Altered metabolism: Drugs can interfere with normal metabolic processes in the body, leading to the accumulation of harmful substances or the depletion of essential nutrients.
3. Hormonal imbalances: Some drugs can affect hormone levels in the body, leading to abnormalities.
4. Allergic reactions: Some people may have allergic reactions to certain drugs, which can cause a range of symptoms, including rashes, swelling, and difficulty breathing.
5. Interactions with other drugs: Taking multiple medications or drugs at the same time can increase the risk of drug-induced abnormalities.

It is important for healthcare providers to monitor patients closely for signs of drug-induced abnormalities and to adjust medication dosages or switch to alternative treatments as necessary. Patients should also inform their healthcare providers of any symptoms they experience while taking medication, as these may be related to drug-induced abnormalities.

Fetal development is the process in which a fertilized egg grows and develops into a fetus, which is a developing human being from the end of the eighth week after conception until birth. This complex process involves many different stages, including:

1. Fertilization: The union of a sperm and an egg to form a zygote.
2. Implantation: The movement of the zygote into the lining of the uterus, where it will begin to grow and develop.
3. Formation of the embryo: The development of the basic structures of the body, including the neural tube (which becomes the brain and spinal cord), heart, gastrointestinal tract, and sensory organs.
4. Differentiation of tissues and organs: The process by which different cells and tissues become specialized to perform specific functions.
5. Growth and maturation: The continued growth and development of the fetus, including the formation of bones, muscles, and other tissues.

Fetal development is a complex and highly regulated process that involves the interaction of genetic and environmental factors. Proper nutrition, prenatal care, and avoidance of harmful substances such as tobacco, alcohol, and drugs are important for ensuring healthy fetal development.

Reproductive history is a term used in medicine to describe the past experiences related to reproduction for an individual. This can include information about pregnancies, including the number of pregnancies, outcomes (such as live births, miscarriages, or stillbirths), and any complications that arose during pregnancy or childbirth. It may also include details about contraceptive use, menstrual history, sexually transmitted infections, and any reproductive health issues or surgeries.

This information is often collected by healthcare providers to help assess fertility, plan for future pregnancies, identify potential risks, and provide appropriate care and management of reproductive health conditions. It's also used in research and public health to understand trends and disparities in reproductive outcomes.

Dizygotic twins, also known as fraternal twins, are a result of two separate sperm fertilizing two separate eggs during conception. These twins share about 50% of their genes, similar to any non-twin siblings. They may be of the same sex or different sexes and can vary in appearance, personality, and interests. Dizygotic twins typically do not share a placenta or a sac in the womb, but they may share a chorion (outer fetal membrane).

I'm sorry for any confusion, but "Wales" is not a medical term. It is a country that is part of the United Kingdom, located in Western Europe. If you have any questions about medical terms or concepts, I would be happy to help answer those!

The term "Fathers" is a general term used to describe male parents or parental figures. It does not have a specific medical definition. In the context of genetics and reproduction, the father is the biological male who contributes his sperm to fertilize an egg, resulting in conception and pregnancy. However, it's important to note that there are many different types of families and parental relationships, and not all fathers are biological parents or male.

I'm sorry for any confusion, but "siblings" is not a medical term. It is a term used in genealogy and sociology to refer to the brothers and sisters that someone has. Sibling relationships can have medical implications, such as when inherited genetic disorders are present in a family, but the term "siblings" itself does not have a specific medical definition.

The pregnancy rate is a measure used in reproductive medicine to determine the frequency or efficiency of conception following certain treatments, interventions, or under specific conditions. It is typically defined as the number of pregnancies per 100 women exposed to the condition being studied over a specified period of time. A pregnancy is confirmed when a woman has a positive result on a pregnancy test or through the detection of a gestational sac on an ultrasound exam.

In clinical trials and research, the pregnancy rate helps healthcare professionals evaluate the effectiveness of various fertility treatments such as in vitro fertilization (IVF), intrauterine insemination (IUI), or ovulation induction medications. The pregnancy rate can also be used to assess the impact of lifestyle factors, environmental exposures, or medical conditions on fertility and conception.

It is important to note that pregnancy rates may vary depending on several factors, including age, the cause of infertility, the type and quality of treatment provided, and individual patient characteristics. Therefore, comparing pregnancy rates between different studies should be done cautiously, considering these potential confounding variables.

I'm not aware of a specific medical definition for "Continental Population Groups." However, in the context of genetics and population health, continental population groups often refer to the major population divisions based on genetic ancestry and geographical origin. These groups typically include:

1. African: Individuals with recent ancestry primarily from Africa, particularly sub-Saharan Africa.
2. European: Individuals with recent ancestry primarily from Europe.
3. Asian: Individuals with recent ancestry primarily from Asia, including East Asia, South Asia, and Central Asia.
4. Native American: Individuals with recent ancestry primarily from the indigenous populations of North, Central, and South America.
5. Oceanian: Individuals with recent ancestry primarily from Australia, New Guinea, and neighboring islands in the Pacific region.

It is important to note that these categories are not exhaustive or mutually exclusive, as human migration and admixture have led to a complex web of genetic ancestries. Furthermore, using continental population labels can oversimplify the rich diversity within each group and may perpetuate harmful stereotypes or misunderstandings about racial and ethnic identities.

Placenta previa is a medical condition that occurs during pregnancy where the placenta partially or fully covers the cervix, which is the lower part of the uterus that opens into the birth canal. This condition can cause severe bleeding during pregnancy and delivery, and it may lead to other complications such as preterm labor and delivery. Placenta previa is typically diagnosed through an ultrasound exam and managed with close monitoring, bed rest, and sometimes cesarean delivery.

I'm sorry for any confusion, but "United States" is a geopolitical entity, specifically the name of the country consisting of 50 states, and it is not a medical term or concept. Therefore, I can't provide a medical definition for it. If you have any questions related to health, medicine, or biology, I would be happy to try to help answer those!

Infectious pregnancy complications refer to infections that occur during pregnancy and can affect the mother, fetus, or both. These infections can lead to serious consequences such as preterm labor, low birth weight, birth defects, stillbirth, or even death. Some common infectious agents that can cause pregnancy complications include:

1. Bacteria: Examples include group B streptococcus, Escherichia coli, and Listeria monocytogenes, which can cause sepsis, meningitis, or pneumonia in the mother and lead to preterm labor or stillbirth.
2. Viruses: Examples include cytomegalovirus, rubella, varicella-zoster, and HIV, which can cause congenital anomalies, developmental delays, or transmission of the virus to the fetus.
3. Parasites: Examples include Toxoplasma gondii, which can cause severe neurological damage in the fetus if transmitted during pregnancy.
4. Fungi: Examples include Candida albicans, which can cause fungal infections in the mother and lead to preterm labor or stillbirth.

Preventive measures such as vaccination, good hygiene practices, and avoiding high-risk behaviors can help reduce the risk of infectious pregnancy complications. Prompt diagnosis and treatment of infections during pregnancy are also crucial to prevent adverse outcomes.

The postpartum period refers to the time frame immediately following childbirth, typically defined as the first 6-12 weeks. During this time, significant physical and emotional changes occur as the body recovers from pregnancy and delivery. Hormone levels fluctuate dramatically, leading to various symptoms such as mood swings, fatigue, and breast engorgement. The reproductive system also undergoes significant changes, with the uterus returning to its pre-pregnancy size and shape, and the cervix closing.

It is essential to monitor physical and emotional health during this period, as complications such as postpartum depression, infection, or difficulty breastfeeding may arise. Regular check-ups with healthcare providers are recommended to ensure a healthy recovery and address any concerns. Additionally, proper rest, nutrition, and support from family and friends can help facilitate a smooth transition into this new phase of life.

I apologize, but "Brazil" is not a medical term or condition. It is the largest country in both South America and Latin America by land area and population. If you have any questions related to medical terminology or health concerns, please provide more information and I will do my best to help.

Genetic testing is a type of medical test that identifies changes in chromosomes, genes, or proteins. The results of a genetic test can confirm or rule out a suspected genetic condition or help determine a person's chance of developing or passing on a genetic disorder. Genetic tests are performed on a sample of blood, hair, skin, amniotic fluid (the fluid that surrounds a fetus during pregnancy), or other tissue. For example, a physician may recommend genetic testing to help diagnose a genetic condition, confirm the presence of a gene mutation known to increase the risk of developing certain cancers, or determine the chance for a couple to have a child with a genetic disorder.

There are several types of genetic tests, including:

* Diagnostic testing: This type of test is used to identify or confirm a suspected genetic condition in an individual. It may be performed before birth (prenatal testing) or at any time during a person's life.
* Predictive testing: This type of test is used to determine the likelihood that a person will develop a genetic disorder. It is typically offered to individuals who have a family history of a genetic condition but do not show any symptoms themselves.
* Carrier testing: This type of test is used to determine whether a person carries a gene mutation for a genetic disorder. It is often offered to couples who are planning to have children and have a family history of a genetic condition or belong to a population that has an increased risk of certain genetic disorders.
* Preimplantation genetic testing: This type of test is used in conjunction with in vitro fertilization (IVF) to identify genetic changes in embryos before they are implanted in the uterus. It can help couples who have a family history of a genetic disorder or who are at risk of having a child with a genetic condition to conceive a child who is free of the genetic change in question.
* Pharmacogenetic testing: This type of test is used to determine how an individual's genes may affect their response to certain medications. It can help healthcare providers choose the most effective medication and dosage for a patient, reducing the risk of adverse drug reactions.

It is important to note that genetic testing should be performed under the guidance of a qualified healthcare professional who can interpret the results and provide appropriate counseling and support.

Alpha-fetoprotein (AFP) is a protein produced by the yolk sac and the liver during fetal development. In adults, AFP is normally present in very low levels in the blood. However, abnormal production of AFP can occur in certain medical conditions, such as:

* Liver cancer or hepatocellular carcinoma (HCC)
* Germ cell tumors, including non-seminomatous testicular cancer and ovarian cancer
* Hepatitis or liver inflammation
* Certain types of benign liver disease, such as cirrhosis or hepatic adenomas

Elevated levels of AFP in the blood can be detected through a simple blood test. This test is often used as a tumor marker to help diagnose and monitor certain types of cancer, particularly HCC. However, it's important to note that an elevated AFP level alone is not enough to diagnose cancer, and further testing is usually needed to confirm the diagnosis. Additionally, some non-cancerous conditions can also cause elevated AFP levels, so it's important to interpret the test results in the context of the individual's medical history and other diagnostic tests.

The term "African Continental Ancestry Group" is a racial category used in the field of genetics and population health to describe individuals who have ancestral origins in the African continent. This group includes people from diverse ethnic backgrounds, cultures, and languages across the African continent. It's important to note that this term is used for genetic and epidemiological research purposes and should not be used to make assumptions about an individual's personal identity, culture, or experiences.

It's also worth noting that there is significant genetic diversity within Africa, and using a single category to describe all individuals with African ancestry can oversimplify this diversity. Therefore, it's more accurate and informative to specify the particular population or region of African ancestry when discussing genetic research or health outcomes.

A confidence interval (CI) is a range of values that is likely to contain the true value of a population parameter with a certain level of confidence. It is commonly used in statistical analysis to express the uncertainty associated with estimates derived from sample data.

For example, if we calculate a 95% confidence interval for the mean height of a population based on a sample of individuals, we can say that we are 95% confident that the true population mean height falls within the calculated range. The width of the confidence interval gives us an idea of how precise our estimate is - narrower intervals indicate more precise estimates, while wider intervals suggest greater uncertainty.

Confidence intervals are typically calculated using statistical formulas that take into account the sample size, standard deviation, and level of confidence desired. They can be used to compare different groups or to evaluate the effectiveness of interventions in medical research.

Body Mass Index (BMI) is a measure used to assess whether a person has a healthy weight for their height. It's calculated by dividing a person's weight in kilograms by the square of their height in meters. Here is the medical definition:

Body Mass Index (BMI) = weight(kg) / [height(m)]^2

According to the World Health Organization, BMI categories are defined as follows:

* Less than 18.5: Underweight
* 18.5-24.9: Normal or healthy weight
* 25.0-29.9: Overweight
* 30.0 and above: Obese

It is important to note that while BMI can be a useful tool for identifying weight issues in populations, it does have limitations when applied to individuals. For example, it may not accurately reflect body fat distribution or muscle mass, which can affect health risks associated with excess weight. Therefore, BMI should be used as one of several factors when evaluating an individual's health status and risk for chronic diseases.

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Trimble, Benjamin, K.; Patricia A. Baird; John M. Opitz (1978). "Maternal age and down syndrome: Age-specific incidence rates ... Maternal age has been shown to be related to intelligence with younger mothers tending have children of lower intelligence than ... However, another study found that when influences such as maternal age, mother's personality and home environment, there was no ... Zybert, P; Stein Z; Belmont L. (1978). "Maternal age and children's ability". Perceptual and Motor Skills. 47 (3): 815-818. doi ...
"Mitochondria, maternal inheritance, and male aging." Current Biology 22.18 (2012): 1717-1721. Dowling, Damian K., A. Larkeson ... Because of maternal inheritance, mtDNA has no selection in males. Instead, mutations only deleterious to males could be ... They demonstrated that mtDNA polymorphism is responsible for male aging, while there is no significant effect on female ... 4 relative to maternal inheritance in mice. Hence, selection can act on male-specific deleterious mutations when they are ...
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Starting around age 35-37, pregnant women are considered to be of advanced maternal age, and declines in fertility begin to ... Middle age is the age range of the years halfway between childhood and old age. The exact range is subject to medical debate, ... When is middle age? We define middle age as "the period of human life between youth and old age, sometimes considered as the ... In general, our age range of "45 to 65" is around the age range generally used to say when middle age supposedly occurs. ...
Camus MF, Clancy DJ, Dowling DK (September 2012). "Mitochondria, maternal inheritance, and male aging". Current Biology. 22 (18 ... The asymmetry of maternal and paternal expression suggests that some kind of conflict between these two genomes might be ... Why inheritance ended up being maternal, rather than paternal, is also much debated, but one key hypothesis is that the ... Due to differences in methylation status of gametes, there is an inherent asymmetry to the maternal and paternal genomes that ...
This tendency increases with maternal age. Fertilization of two different oocytes by two different spermatozoa results in ... Geirsson RT (May 1991). "Ultrasound instead of last menstrual period as the basis of gestational age assignment". Ultrasound in ...
"Attention-deficit/hyperactivity disorder in school-aged children: association with maternal mental health and use of health ... The continuity of maternal stress from during, to after, pregnancy is a progression of maternal-foetal stress transfer which is ... leading to physiological manifestations of stress such as increased maternal blood pressure (MBP) and maternal heart rate (MHR ... This is that maternal-foetal stress transfer occurs through the mechanism of cortisol moving from mother to baby through the ...
Nondisjunction is related to advanced maternal age, although due to its rarity, the maternal age effect in pentasomy X is ... Dey, Subrata Kumar; Ghosh, Sujoy (29 August 2011). "Etiology of Down Syndrome: Risk of Advanced Maternal Age and Altered ... Mikwar M, MacFarlane AJ, Marchetti F (4 July 2020). "Mechanisms of oocyte aneuploidy associated with advanced maternal age". ... Chiang T, Schultz RM, Lampson MA (1 January 2012). "Meiotic Origins of Maternal Age-Related Aneuploidy". Biology of ...
Young maternal age and increases the risk. Studies differ whether the risk is different in different trimesters. Limited data ... The risk of severe malaria by Plasmodium falciparum is three times as high in pregnant women, with a median maternal mortality ... Maternal physiological changes including a decrease in respiratory volumes and urinary stasis due to an enlarging uterus. The ...
Frick AP (January 2021). "Advanced maternal age and adverse pregnancy outcomes". Best Practice & Research. Clinical Obstetrics ... Age Older age - Pregnancies in women over the age of 35 are considered "advanced age". First-time pregnant women in this age ... Frick AP (January 2021). "Advanced maternal age and adverse pregnancy outcomes". Best Practice & Research. Clinical Obstetrics ... Younger age - Pregnant teenagers are more likely to develop anemia, have preterm births, and have low birth weight babies. ...
Hassold T, Jacobs P, Kline J, Stein Z, Warburton D (July 1980). "Effect of maternal age on autosomal trisomies". Annals of ... The probability of nondisjunction in human oocytes increases with increasing maternal age, presumably due to loss of cohesin ... Tsutsumi M, Fujiwara R, Nishizawa H, Ito M, Kogo H, Inagaki H, Ohye T, Kato T, Fujii T, Kurahashi H (May 2014). "Age-related ... Because of recombination, an individual chromatid can consist of a new combination of maternal and paternal genetic information ...
Another risk factor for developing any pregnancy complications is maternal age. Advanced maternal age, considered to be when a ... Risk factors such as hypertensive medical conditions, maternal age, and substance use are just some of the things that can put ... "Meiotic Origins of Maternal Age-Related Aneuploidy". Biology of Reproduction. 86 (1): 3. doi:10.1095/biolreprod.111.094367. ... of maternal deaths from 2011 to 2015. High blood pressure during pregnancy can potentially damage maternal organ systems such ...
The relation between number of older brothers and male homosexuality is not an artifact of higher maternal or paternal age at ... Slater E (13 January 1962). "Birth order and maternal age of homosexuals". The Lancet. 1 (7220): 69-71. doi:10.1016/S0140-6736( ... It has generally been thought that this maternal response would not apply to first born gay sons and that they may owe their ... This implies that the birth order phenomenon cannot be explained by increased mutation rates in the ova or sperm cells of aging ...
... incidence increases substantially as maternal age rises. Less is understood about the role of maternal age in sex chromosome ... Dey, Subrata Kumar; Ghosh, Sujoy (29 August 2011). "Etiology of Down Syndrome: Risk of Advanced Maternal Age and Altered ... Nondisjunction is related to advanced maternal age. In common aneuploidies such as Down syndrome, the relationship with ... Mikwar M, MacFarlane AJ, Marchetti F (4 July 2020). "Mechanisms of oocyte aneuploidy associated with advanced maternal age". ...
Campbell CL, Furlotte NA, Eriksson N, Hinds D, Auton A (2015). "Escape from crossover interference increases with maternal age ... In humans, recombination rate increases with maternal age. Furthermore, placement of female recombination events appears to ... become increasingly deregulated with maternal age, with a larger fraction of events occurring within closer proximity to each ...
Maternal age and its negative effects on oocytes plays a key role in the reduction of fertility in women over 35 years of age. ... A high maternal age is associated with increased chromosome segregation errors during meiosis as well, which leads to oocyte ... Moreover, ageing is associated with oocyte abnormalities since higher maternal age is associated with oocytes with a reduced ... The principal oocyte abnormality associated with increased maternal age is aneuploidy, in which chromosome segregation errors ...
Maternal age is the only known risk factor. Women at 40 years have a four-times-higher risk of a child with Klinefelter ... The extra chromosome is retained because of a nondisjunction event during paternal meiosis I, maternal meiosis I, or maternal ... They may have less muscle control and coordination than other boys of their age. During puberty, the physical traits of the ...
The risk of Trisomy 21 increases with maternal age with the risk being 1/2000 (0.05%) at age 20 increasing to 1/100 (1%) at age ... Hassold T, Hunt P (December 2009). "Maternal age and chromosomally abnormal pregnancies: what we know and what we wish we knew ... Hook, EB (September 1981). "Rates of chromosome abnormalities at different maternal ages". Obstetrics and Gynecology. 27 (1): ... "New observations on maternal age effect on germline de novo mutations". Nature Communications. 7: 10486. Bibcode:2016NatCo... ...
Still, advanced maternal age causes decreased success rates; women aged 38-39 years appear to have reasonable success during ... maternal age, follicle count at hCG administration day, follicle rupture, and the number of uterine contractions observed after ... Women whose age is becoming a major factor in fertility may not want to spend that extra time. The number of samples ( ... However, for women aged over 40 years, there appears to be no benefit after a single cycle of COH/IUI. Medical experts ...
It is more likely with advanced maternal age. Some oocytes have multiple nuclei, although it is thought they never mature. ... Maternal cells also synthesize and contribute a store of ribosomes that are required for the translation of proteins before the ... Sundaram N, Tao Q, Wylie C, Heasman J (September 2003). "The role of maternal CREB in early embryogenesis of Xenopus laevis". ... Ogushi S, Palmieri C, Fulka H, Saitou M, Miyano T, Fulka J (February 2008). "The maternal nucleolus is essential for early ...
As maternal age increases so does egg size. At the beginning of the breeding season females lay smaller eggs compared to the ... It has been suggested that the two species diverged during Pleistocene ice age. Both have the same number of chromosomes (2n=17 ... Eggs laid in the last part of the breeding season are smaller in size due to deteriorating maternal health. Research suggests ... depending on the female's age and its origins". Comparative Biochemistry and Physiology C. 154 (3): 172-179. doi:10.1016/j.cbpc ...
Maternal age effect Pregnancy over age 50 "paternal age effect". Retrieved 28 May 2015. Amaral, David; Dawson, Geraldine; ... which found that maternal age began to correlate with lower intelligence at a younger age than paternal age, however two other ... There is no similar relationship with maternal age. A second study also found a risk of schizophrenia in both fathers above age ... Weinberg "made no distinction between paternal age, maternal age and birth order" in his hypothesis. In 1953, Krooth used the ...
Full maternal inheritance is present within DM1, repeat expansion length is linked to maternal age and the earliest instance of ... "Increased trinucleotide repeat instability with advanced maternal age". Human Molecular Genetics. 6 (12): 2135-2139. doi: ... Maternal transmission has been observed to only consist of an increase in repeat units of 1 while the paternal transmission is ... Typical age at symptom onset is 5-15, with symptoms progressively getting worse over time. Friedreich's ataxia is an autosomal ...
The leaders of the maternal feminist movement were middle-aged and the maternal feminist movement was in decline. There was ... However, the WCTU saw women purely as wives and mothers, accepting the constraints of maternal feminism. Maternal feminism ... Diniejko, Dr Andrzej (2014). "Maternal feminism". Frances Trollope: a Maternal Feminist and Social Reformer. Retrieved 2014-08- ... The concept of maternal feminism is resilient. In January 1993 CBS debuted a "soft" drama for family viewing called Dr. Quinn, ...
Paternal age effect Advanced maternal age Pregnancy over age 50 "Having a Baby After Age 35: How Aging Affects Fertility and ... At age 20, 1 in 2000 At age 24, 1 in 1300 At age 25, 1 in 1200 At age 29, 1 in 950 At age 30, 1 in 900 At age 34, 1 in 450 At ... age 35, 1 in 350 At age 39, 1 in 150 At age 40, 1 in 100 At age 44, 1 in 40 At age 45, 1 in 30 At age 49, 1 in 10 In addition ... While many women in advanced age may opt for IVF treatment in order to have children, patients with higher maternal age (>40 ...
December 2021). "Prenatal maternal posttraumatic stress disorder as a risk factor for adverse birth weight and gestational age ... Small for gestational age is defined as below the 10th percentile for gestational age and sex. Low birth weight can also be ... Low birth weight can also vary by maternal age. In 2008 the rate of low birth weight was the highest in babies born to women ... A low birth weight can be caused either by a preterm birth (low gestational age at birth) or the infant being small for ...
Proportion of maternal deaths among deaths of women of reproductive age (PM) is the number of maternal deaths in a given time ... The four measures of maternal death are the maternal mortality ratio (MMR), maternal mortality rate, lifetime risk of maternal ... These are the maternal mortality ratio and maternal mortality rate, both abbreviated as "MMR". By 2017, the world maternal ... The adult lifetime risk of maternal mortality can be derived using either the maternal mortality ratio (MMR), or the maternal ...
Advanced maternal age, in a broad sense, is the instance of a woman being of an older age at a stage of reproduction, although ... Finally, although older maternal age doesnt necessarily imply older paternal age, researchers have suggested links between ... In the U.S., the average age of first childbirth was 26.9 in 2018. Advanced maternal age is associated with adverse ... The above table is not to be confused with maternal mortality. Advanced maternal age continues to be associated with a range of ...
Preterm birth rates declined for all age groups and overall from 10.41% to 9.54% of live births. ... Preterm birth rates declined for all age groups and overall from 10.41% to 9.54% of live births. ... by maternal age - United States, 2007 and 2014. Maternal. age (yrs). All births. Preterm births. Rate change components*. ... Mean maternal age increased from 27.4 years to 28.3 years. The contribution of fewer births to teens and to women aged 20−24 ...
Action - GNPR 2009-2010: Maternal, infant and young child nutrition - Management of severe acute malnutrition - Preschool-age ... GNPR 2009-2010: Maternal, infant and young child nutrition - Promotion and implementation of properly timed cord clamping - ... Module 2 on Maternal, infant and young child nutrition. Please note that for simplicity, all interventions in a thematic module ...
GNPR 2009-2010: Maternal, infant and young child nutrition - Preventive malaria treatment - Women of reproductive age (WRA) ... GNPR 2009-2010: Maternal, infant and young child nutrition - Management of severe acute malnutrition - Preschool-age children ( ... Action - GNPR 2009-2010: Maternal, infant and young child nutrition - Management of moderate malnutrition - Preschool-age ... GNPR 2009-2010: Maternal, infant and young child nutrition - Counselling on nutritional support&care for people living with HIV ...
GNPR 2009-2010: Maternal, infant and young child nutrition - Management of severe acute malnutrition - Preschool-age children ( ... Action - GNPR 2009-2010: Maternal, infant and young child nutrition - Preventive malaria treatment - Women of reproductive age ... GNPR 2009-2010: Maternal, infant and young child nutrition - Counselling on nutritional support&care for people living with HIV ... GNPR 2009-2010: Maternal, infant and young child nutrition - Breastfeeding promotion and/or counselling - Infants (up to 1 year ...
GNPR 2009-2010: Maternal, infant and young child nutrition - Preventive malaria treatment - Women of reproductive age (WRA) ... GNPR 2009-2010: Maternal, infant and young child nutrition - Management of moderate malnutrition - Preschool-age children (Pre- ... Action - GNPR 2009-2010: Maternal, infant and young child nutrition - Management of severe acute malnutrition - Preschool-age ... GNPR 2009-2010: Maternal, infant and young child nutrition - Counselling on nutritional support&care for people living with HIV ...
... an estimated 1,205 women died due to maternal causes in the United States. ... Maternal hepatitis C infection rate in the U.S. 2016-2021. *Maternal hepatitis C infection rate in the U.S. in 2021, by age of ... Number of maternal deaths in the United States from 2018 to 2021, by age table column chart ... Number of maternal deaths in the U.S. from 2018 to 2021, by age Published by John Elflein, ...
A 755% increase in reported cases since 2012 highlights the need for timely testing and treatment to prevent maternal and ... A 755% increase in reported cases since 2012 highlights the need for timely testing and treatment to prevent maternal and ...
This report describes maternal mRNA vaccine effectiveness against COVID-19 hospitalizations among infants under 6 months of age ... This report describes maternal mRNA vaccine effectiveness against COVID-19 hospitalizations among infants under 6 months of age ... TABLE 2. Clinical outcomes and severity among case-infants aged ,6 months hospitalized with COVID-19, by maternal vaccination ... Effectiveness of maternal vaccination during pregnancy against COVID-19 hospitalization in infants aged ,6 months was 61% (95% ...
Older maternal age accounts for about one-third of the rise, and two-thirds is due to the increased use of fertility treatments ... Home Pregnancy News High maternal age and fertility treatments lead to twins: Study ... Notably, women aged 30 and older appeared to face more twin births, though the results were consistent across females of all ... ages. According to the team, multiple births may have certain health implications in terms of death and morbidity risks. ...
Preterm birth data helps connect the story between gestational age and birth outcomes. ... Maternal age is a risk factor for preterm birth, with higher preterm birth rates found among the youngest and oldest mothers in ... followed by women ages 40 and older (9.7%), ages 30-39 (9.4%) and ages 20-29 (8.8%). ... During 2019-2021 (average) in Maine, preterm birth rates were highest for women under age 20 (9.9%), ...
We hypothesize that BM antioxidants are adapted to gestational age and are negatively influenced by maternal age. Fifty ... Regression models evidenced a negative association between maternal age and BM melatonin levels (β = −7.4 ± 2.5; p-value = ... Mixed random-effects linear regression models were used to study the influence of maternal and gestational ages on BM ... BM antioxidants are adapted to gestational age providing higher levels to infants with lower degree of maturation; maternal ...
Maternal education and household income at birth can increase a childs chances of overweight and obesity at age 10, according ... Read the cited paper: "Household income and maternal education in early childhood and risk of overweight and obesity in late ... Although the trends between maternal education and household income to childhood overweight/obesity were present across all ... as measured by maternal education levels and household income - and later development of childhood overweight and obesity in ...
November 2021): Theory of Mind in Pre-school Aged Children: Influence of Maternal Depression and Infants Self-Comforting ... to evaluate maternal psychopathological status according to DSM-IV. At the age of M = 4.0 years, childrens ToM abilities were ... Theory of mind; maternal depression; infant self-comforting behaviors; Face-to-Face Still-Face paradigm; gender differences in ... The present study investigated the relation of self-regulatory abilities in infancy and later ToM in pre-school aged children ...
Maternal Links: Genetic risk maternal age , Placenta - Maternal Decidua , maternal diabetes , maternal hyperthermia , maternal ... Age Table. Genetic Risk Maternal Age Age of Mother. Risk of Trisomy 21. Risk of Any Chromosomal Abnormality. ... maternal diabetes , maternal hypertension , maternal hyperthermia , Maternal Inflammation , Maternal Obesity , hypoxia , ... and higher in the middle age group (3.6). Lastly, we found no effect of grand-maternal age on the risk for maternal ...
The sample consisted of fourth-grade students aged 10 y recruited from nine elementary schools in Korean urban areas in 2008 (n ... maternal education is important in reducing the risk of anemia and iron deficiency and in increasing childrens consumption of ... Logistic regression analysis revealed a significant inverse relationship between maternal education and the prevalence of ... and iron deficiency among school-aged children in Korea. ... From: Effects of maternal education on diet, anemia, and iron ...
Corrections: Maternal seafood intake and the risk of small for gestational age newborns: a case-control study in Spanish women ... Corrections: Maternal seafood intake and the risk of small for gestational age newborns: a case-control study in Spanish women ... Maternal seafood intake and the risk of small for gestational age newborns: a case-control study in Spanish women - August 01, ... Corrections: Maternal seafood intake and the risk of small for gestational age newborns: a case-control study in Spanish women ...
This study investigated the effect of paternal and maternal silent coeliac disease on birthweight and gestational age in ... The Evaluation of the Effects of Paternal and Maternal Silent Coeliac Disease on Birthweight and Gestational Age in Newborns ... This study investigated the effect of paternal and maternal silent coeliac disease on birthweight and gestational age in ... premature small gestational age and term small gestational age infants (p , 0.05), but statistically significant in mothers (p ...
Advanced maternal age, gestational age and intrauterine growth restriction were independently associated with milk protein ... Gestational age negatively correlated with protein (rho: −0.307, p < 0.001) and energy (r: −0.193, p = 0.003). ... Maternal age. Some differences have been reported regarding fat content in relation to maternal age [11, 36,37,38], but not ... Maternal conditions. Advanced maternal age was related to higher milk protein concentration (Table 2), without differences in ...
Inequalities in mortality of infants under one year of age according to foetal causes and maternal age in rural and urban areas ... Analysis of mortality in Poland from foetal and maternal causes (length of gestation, birth weight, maternal age) in the ... and maternal age. Trend analysis and comparison of mortality between rural and urban areas were performed using the Poisson ... The mortality rate was also higher in rural areas in children born to women aged 20-34 years, and children born after 37 weeks ...
Models were adjusted for potential maternal, socioeconomic, and child confounders such as maternal education, deprivation, and ... and child development outcomes at age 5, using cord blood markers as candidate mediators. Maternal cardiometabolic markers ... After adjusting for maternal, child, and environmental covariates, maternal metabolic syndrome classification during pregnancy ... that maternal metabolic syndrome classification during pregnancy is associated with some child developmental outcomes at age 5 ...
There was a strong association between young maternal age and high infant mortality and between young maternal age and a high ... Young maternal age and infant mortality: the role of low birth weight.. 102(2). Friede, Andrew et al. "Young maternal age and ... association between young maternal age and postneonatal mortality persisted after birth weight adjustment in all maternal age ... Adolescent Adult Birth Weight Black People Child Health Surveys Humans Infant Infant, Newborn Infant Mortality Maternal Age ...
Maternal participants in the Interactive Autism Network (IAN) with at least one teen/young adult aged 15-29 were recruited to ... Greater maternal perceived stress (PSS) + presence of another teen/young adult (15-29 years) in the home with ASD/disability ... Greater maternal perceived stress + presence of another teen/young adult (15-29 years) in the home with ASD/disability + male ... Previous studies have focused primarily on the well-being of mothers of young, school-aged children; however, little is known ...
Maternal age. In women aged 13-15 years, the rate of preterm birth is 5.9%. [13] This rate declines to 1.7% in women aged 18-19 ... Maternal fever (,38ºC [,100.4ºF]), fetal tachycardia, maternal leukocytosis (,15,000-18,000/mm3 [15-18 × 109/L]), and uterine ... These complications are gestational age dependent. Complications are inversely proportionate to gestational age. [20] These ... Changes in neurodevelopmental outcome at age eight in geographic cohorts of children born at 22-27 weeks gestational age ...
... adversely affecting maternal health and child undernutrition. This study investigated the association between maternal age at ... Young Maternal Age at first birth and Child Undernutrition in Bangladesh: Evidence from the Bangladesh Demographic Health ... Young Maternal Age at first birth and Child Undernutrition in Bangladesh: Evidence from the Bangladesh Demographic Health ... Young Maternal Age at first birth and Child Undernutrition in Bangladesh: Evidence from the Bangladesh Demographic Health ...
Identification of potential molecular pathways involved in prostate carcinogenesis in offspring exposed to maternal ...
... with the most significant influences being gestational age at delivery, maternal prepregnancy body mass index (BMI), maternal ... Maternal-Fetal Metabolism in Diabetes. If the maternal pancreatic insulin response is inadequate, maternal and, then, fetal ... Maternal Morbidity. Diabetic retinopathy. Diabetic retinopathy is the leading cause of blindness in women aged 24-64 years. ... Maternal obesity has a strong and independent effect on fetal macrosomia. Birth weight is largely determined by maternal ...
  • The paper, published in Nature's International Journal of Obesity , looks at the relation between early childhood socioeconomic status (SES) - as measured by maternal education levels and household income - and later development of childhood overweight and obesity in seven cohorts of children from high-income countries. (concordia.ca)
  • Social inequalities were evident across all cohorts, with greater risk of overweight and obesity linked to lower levels of maternal education in early childhood. (concordia.ca)
  • Although the trends between maternal education and household income to childhood overweight/obesity were present across all seven cohorts, the strength of the association differed between jurisdictions. (concordia.ca)
  • Altered early growth likely influences the metabolic syndrome pathway, with obesity and T2D both occurring at a younger age [ 7 ]. (nature.com)
  • Poor maternal health, including obesity and high-stress levels. (mana.org)
  • Dr. Carter is well published in her field of medicine with interests in maternal obesity and diabetes and understanding the risks associated with preterm delivery. (huntsvillehospital.org)
  • We used a Japanese macaque model to investigate whether maternal obesity combined with a Western-style diet (WSD) impairs offspring muscle insulin action. (diabetesjournals.org)
  • This study uses a cohort sample of 12,644 to 13,832 mother-child pairs from the UK Born in Bradford Study to examine the associations between maternal metabolic syndrome classification (MetS) and child development outcomes at age 5, using cord blood markers as candidate mediators. (biomedcentral.com)
  • Our primary objective was to examine the associations between maternal age and severe maternal morbidities. (giuliamuraca.com)
  • This study aims to reveal the associations between maternal hemoglobin concentrations in different trimesters of pregnancy and neonatal birth weight, LBW, and SGA. (lstmed.ac.uk)
  • Among the 1 336 356 women who delivered between 2003 and 2007, the rate of severe maternal morbidity was 13.8 per 1000 deliveries. (nih.gov)
  • The rate of severe maternal morbidity among women over 49 y was higher than the rate of mortality/serious morbidity of their offspring. (giuliamuraca.com)
  • Down syndrome is the most common chromosomal birth defect, and a woman's risk of having a baby with Down syndrome is: Risk of having a baby with Down syndrome Advanced maternal age is associated with adverse outcomes in the perinatal period, which may be caused by detrimental effects on decidual and placental development. (wikipedia.org)
  • Advanced maternal age continues to be associated with a range of adverse pregnancy outcomes including low birth weight, pre-term birth, stillbirth, unexplained fetal death, and increased rates of Caesarean section. (wikipedia.org)
  • Interestingly, recent studies suggest that increasing paternal age (father's age) can also have affects on childhood mortality [4] and neurodevelopmental outcomes. (edu.au)
  • There is limited evidence on how the classification of maternal metabolic syndrome during pregnancy affects children's developmental outcomes and the possible mediators of this association. (biomedcentral.com)
  • The results support the hypothesis that maternal metabolic syndrome classification during pregnancy is associated with some child developmental outcomes at age 5. (biomedcentral.com)
  • It is alarming that the CDC's new report shows that maternal mortality rates continued to rise in the U.S. in 2021, with persistent racial disparities in maternal health outcomes," AAFP President Tochi Iroku-Malize, MD, MPH, said in a statement. (medpagetoday.com)
  • In this prospective cohort study following 426 mother-child dyads from pregnancy to middle childhood, women reported stressful life events (SLEs) experienced during the 12 months before delivery and AD outcomes in children aged approximately 4-6 years, including current- and location-specific AD and ever AD. (washington.edu)
  • We compared age-specific rates of maternal mortality/severe morbidity (e.g., obstetric shock) and adverse fetal/infant outcomes (e.g., perinatal death). (giuliamuraca.com)
  • Adverse birth outcomes, such as early gestational age and low birth weight, can have lasting effects on morbidity and mortality, with impacts that persist into adulthood. (biomedcentral.com)
  • Identifying the maternal factors that contribute to adverse birth outcomes in the next generation is thus a priority. (biomedcentral.com)
  • Epigenetic clocks, which have emerged as powerful tools for quantifying biological aging and various dimensions of physiological dysregulation, hold promise for clarifying relationships between maternal biology and infant health, including the maternal factors or states that predict birth outcomes. (biomedcentral.com)
  • Nevertheless, studies exploring the relationship between maternal epigenetic age and birth outcomes remain few. (biomedcentral.com)
  • Birth outcomes like birth weight, length, and gestational age predict both short- and long-term health. (biomedcentral.com)
  • There is limited large-scale evidence of the relationship between maternal age and child outcomes beyond the perinatal period. (edu.au)
  • Birth weight and related outcomes have profound influences on life cycle health, but the effect of maternal hemoglobin concentration during pregnancy on birth weight is still unclear. (lstmed.ac.uk)
  • Information on maternal socio-demographic status, health-related factors, antenatal visits, and neonatal birth outcomes were collected. (lstmed.ac.uk)
  • Previous studies indicated a range of risk factors associated with these poor outcomes, including maternal psychosocial and economic wellbeing. (springer.com)
  • The team looked at data on maternal milk dose (volume of maternal milk infants received each day) and maternal milk duration (how long parents continued breastfeeding) predicted several neurodevelopmental outcomes. (globalwomenshealthacademy.org)
  • The study's strengths include its large size, the range of outcomes examined, and that the researchers could assess school-age outcomes. (globalwomenshealthacademy.org)
  • Other studies have only followed children through preschool age, making it difficult to assess the full range of neurodevelopmental outcomes. (globalwomenshealthacademy.org)
  • Harris D, Aboueissa A, Baugh N, Sarton C. Impact of rurality on maternal and infant health indicators and outcomes in Maine. (rrh.org.au)
  • this approach tends to result in the best balance of maternal and fetal outcomes. (msdmanuals.com)
  • The risk of the mother dying before the child becomes an adult increases by more advanced maternal age, such as can be demonstrated by the following data from France in 2007: The above table is not to be confused with maternal mortality. (wikipedia.org)
  • Young maternal age and infant mortality: the role of low birth weight. (cdc.gov)
  • Irrespective of definition, birth defects can cause spontaneous abortions and stillbirths and are a significant but underrecognized cause of mortality and disability among infants and children under five years of age. (who.int)
  • However, existing figures indicate that work on reducing the incidence of and mortality associated with congenital anomalies needs to be linked to efforts to achieve the Millennium Development Goal 4 target of a two thirds reduction in the mortality rate of children under five years of age between 1990 and 2015. (who.int)
  • Maternal mortality in the U.S. significantly increased in 2021 compared with the previous year, the CDC reported Thursday. (medpagetoday.com)
  • The maternal mortality rate for 2021 was 32.9 deaths per 100,000 live births, compared with a rate of 23.8 in 2020 and 20.1 in 2019. (medpagetoday.com)
  • Death rates varied by racial/ethnic groups, with the maternal mortality rate for non-Hispanic Black patients at 69.9 per 100,000 live births, which was 2.6 times the death rate for non-Hispanic white women (26.6 per 100,000). (medpagetoday.com)
  • we cannot let that fact obscure that there was -- and still is -- already a maternal mortality crisis to compound," Hoskins continued. (medpagetoday.com)
  • The maternal mortality increases will likely be impacted by another factor: the Supreme Court's overturning of Roe v. Wade , wrote Jen Villavicencio, MD, MPP, ACOG's lead for equity transformation, in an email to MedPage Today . (medpagetoday.com)
  • In the wake of that decision, "we've seen abortion bans and restrictions take effect in various states across the country and, as a result, we can expect to see the U.S. maternal mortality crisis exacerbated," she added. (medpagetoday.com)
  • To be clear, the worsening U.S. maternal mortality rate cannot be addressed without addressing how each American can access safe abortion care if and when they need it," Villavicencio noted. (medpagetoday.com)
  • Detailed data on Afghan mothers' characteristics, morbidity and mortality from 2017 to 2019 were extracted from the electronic registration system of the Ministry of Health and Medical Education's Maternal Health Office. (who.int)
  • The Afghan mothers' maternal mortality ratio was 43 per 100 000 for these three years. (who.int)
  • According to the WHO report, Maternal mortality: Levels and trends 2000 to 2017, Afghanistan is among the countries with a high (500-999) maternal mortality ratio (MMR). (who.int)
  • This information is also useful for preventive strategies to lower maternal mortality and severe maternal morbidity in developed countries. (giuliamuraca.com)
  • Objectives Preterm birth (PTB) and small for gestational age (SGA) are major causes of perinatal mortality and morbidity. (springer.com)
  • The contribution of fewer births to teens and to women aged 20−24 years to the overall decline in preterm births was offset by increases in births to older mothers. (cdc.gov)
  • Rates of preterm births vary by maternal age, being higher among the youngest and oldest mothers. (cdc.gov)
  • The effects of age distribution changes on the preterm birth rate decrease were different in younger and older mothers. (cdc.gov)
  • The decrease in the proportion of births to mothers aged ≤19 and 20−24 years and reductions in age-specific preterm rates in all age groups contributed to the overall decline in the preterm birth rate. (cdc.gov)
  • The increase in births to mothers aged ≥30 years had no effect on the overall preterm birth rate decrease. (cdc.gov)
  • A decrease in the percentage of births to mothers aged ≤24 years was observed, which included a 39.5% decrease in births to teens and an increase in births to women aged ≥25 years ( Table ). (cdc.gov)
  • Maternal age is a risk factor for preterm birth, with higher preterm birth rates found among the youngest and oldest mothers in the U.S. (marchofdimes.org)
  • However, differences were more apparent when comparing the relative and absolute risk: For relative risk, Quebec children of mothers with low educational attainment relative to those with higher education attainment at birth were about three times more likely to be obese at age 10, compared to only 1.5 times for Canadian children. (concordia.ca)
  • Yet, when accounting for distribution of socioeconomic status across the population, Canadian children of mothers with low educational attainment or household income at birth had a higher absolute risk of being either overweight or obese at age 10. (concordia.ca)
  • The present study investigated the relation of self-regulatory abilities in infancy and later ToM in pre-school aged children of clinically depressed mothers and healthy controls. (uni-muenchen.de)
  • At 3 and 42 months postpartum mothers were interviewed with the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) to evaluate maternal psychopathological status according to DSM-IV. (uni-muenchen.de)
  • Silent coeliac disease may occur in parents, especially in mothers of preterm and small for gestational age infants, even in the absence of apparent clinical indications. (uwi.edu)
  • This combination of child, maternal and social factors is similar to that reported for mothers of younger children with ASD. (confex.com)
  • Total prevalence for all CHD combined was increased for younger mothers (≤24 years) and for mothers 35-44 years of age when compared with mothers aged 25-29 years (reference group) (IRR 1.05, 95% CI 1.02, 1.07). (bvsalud.org)
  • The total prevalence was increased for severity group I (very severe) only for younger mothers compared to those aged 25-29 years (IRR 1.14, 95% CI 1.04, 1.23). (bvsalud.org)
  • Based on data for cases of CHD from 24 European population -based registries , evidence of a positive association between maternal age and the total prevalence of CHD for younger (≤24 years old) and older (35-44 years old) mothers was observed. (bvsalud.org)
  • This cross-sectional study included 98 adolescents (up to 18 year-old) and 33 advanced maternal age (more than 35 year-old) mothers admitted at the maternity of Presidente Prudente Regional Hospital, Brazil. (bvsalud.org)
  • The median age adolescents and advanced maternal age mothers were 20 years (12-24) 37 years (35-45), respectively. (bvsalud.org)
  • The majority of the adolescents (66.3%) were primiparous and C-section delivery had occurred in 66.7% of advanced age mothers. (bvsalud.org)
  • Sociodemographic and gestational characteristics of adolescents and advanced age mothers showed population heterogeneity, thus, specific follow up and orientations should be applied at each one. (bvsalud.org)
  • Background: The health care system of the Islamic Republic of Iran provides special maternal health services for mothers, regardless of their nationality. (who.int)
  • Evidence suggests that parents within an older age bracket [7] - mothers 40-49 years and fathers above 50 years - are more likely to have a child with an ASD diagnosis later down the line. (mana.org)
  • Severe maternal morbidity was significantly higher among teenage mothers than among those 25-29 y (crude OR = 1.5, 95% CI 1.5-1.6) and increased exponentially with maternal age over 39 y, from OR = 1.2 (95% CI 1.2-1.3) among women aged 35-39 y to OR = 5.4 (95% CI 2.4-12.5) among women aged ≥50 y. (giuliamuraca.com)
  • The elevated risk of severe morbidity among teen mothers disappeared after adjustment for confounders, except for maternal sepsis (AOR = 1.2, 95% CI 1.1-1.4). (giuliamuraca.com)
  • 20 years and 20,026 children (20.1%) born to mothers aged ≥35 years. (edu.au)
  • Adjustment for sociodemographic characteristics significantly attenuated vulnerability risk in children born to younger mothers, while adjustment for potentially modifiable factors, such as antenatal visits, had little additional impact across all ages. (edu.au)
  • Conclusions: Increasing maternal age was associated with a lesser risk of developmental vulnerability for children born to mothers aged 15 years to about 30 years. (edu.au)
  • In contrast, increasing maternal age beyond 35 years was generally associated with increasing vulnerability, broadly equivalent to the risk for children born to mothers in their early twenties, which is highly relevant in the international context of later childbearing. (edu.au)
  • Children of clinically depressed mothers were exposed to more risk factors associated with maternal mental health. (cambridge.org)
  • Children of clinically depressed mothers are exposed to both maternal psychopathology and risks that are associated with maternal mental health. (cambridge.org)
  • Maternal depression is a significant public health concern because of its negative impact on both the mothers and their children. (cambridge.org)
  • In maternal and child health, these disparities may be evidenced by the health risks and behaviors of new mothers, the health of infants born to these mothers, and the care received by both mothers and infants. (rrh.org.au)
  • Compared to mothers from more urban areas, rural mothers were not sure they were pregnant until a later gestational age but received prenatal care just as early and were just as likely to receive prenatal care as early as they wished. (rrh.org.au)
  • Seven hundred and fifty-six mothers with at least one child aged 0-23 months took part in this study. (nih.gov)
  • The article analyzes data from a large electronic database of births to draw conclusions about pregnancy over age 35. (howardisms.com)
  • Conclusions Maternal age-specific incidence of severe morbidity varied by outcome. (giuliamuraca.com)
  • To examine the feasibility of using routine labour and delivery hospitalization data and international classification of diseases (ICD-10CA) codes for carrying out surveillance of severe maternal morbidity in Canada. (nih.gov)
  • Severe maternal morbidity rates in Canada (excluding Quebec) for the period 2003 to 2007 were estimated using the Discharge Abstract Database of the Canadian Institute for Health Information. (nih.gov)
  • Rates of severe maternal morbidity were higher among deliveries to older and nulliparous women and to those delivering twins or triplets. (nih.gov)
  • Disease frequency, case fatality, and length of hospitalization patterns suggest that comprehensive and timely surveillance of severe maternal morbidity in Canada is feasible using the Canadian Institute for Health Information hospitalization data and ICD-10CA/CCI codes. (nih.gov)
  • As average maternal age continues to rise in these countries, associated potentially life-threatening severe maternal morbidity has been understudied. (giuliamuraca.com)
  • Recent trends in placenta accreta in the United States and its impact on maternal-fetal morbidity and healthcare-associated costs, 1998-2011. (msdmanuals.com)
  • These programmes and actions were reported by countries for the WHO Global Nutrition Policy Review 2009-2010, Module 2 on Maternal, infant and young child nutrition. (who.int)
  • Information on the impact of maternal, gestational or neonatal characteristics on milk macronutrient composition could help identify mother-infant pairs at higher risk of extrauterine growth restriction and move towards a more individualized nutritional support [ 24 ]. (nature.com)
  • 2 Maternal and Infant Health Section, Public Health Agency of Canada, Ottawa ON. (nih.gov)
  • Maternal smoking during pregnancy is an established risk factor for low infant birth weight, but evidence on critical exposure windows and timing of fetal growth restriction is limited. (plos.org)
  • Maternal smoking during pregnancy is an established risk factor for low infant birth weight. (plos.org)
  • On the other hand, advanced maternal age is associated with a more stable family environment, higher socio-economic position, higher income and better living conditions, as well as better parenting practices (including better disciplinary methods). (wikipedia.org)
  • Using rate decomposition methods, the change in preterm birth rates from 2007 to 2014 was divided into two components: 1) changes in the maternal age distribution, and 2) changes in the age-specific preterm birth rates ( 4 ). (cdc.gov)
  • Using novel applications of brain-age prediction methods, we found that a higher number of previous childbirths were linked to less apparent brain aging in striatal and limbic regions. (ox.ac.uk)
  • METHODS: This total-population register-based cohort study consisted of 628 312 singleton women born in Sweden between 1973 and 1987, who were followed for diagnosed endometriosis from age 15 years until the end of 2012. (lu.se)
  • Evidence from other vaccine-preventable diseases suggests that maternal immunization can provide protection to infants, especially during the high-risk first 6 months of life, through passive transplacental antibody transfer ( 2 ). (cdc.gov)
  • however, no epidemiologic evidence currently exists for the protective benefits of maternal immunization during pregnancy against COVID-19 in infants. (cdc.gov)
  • The Overcoming COVID-19 network conducted a test-negative, case-control study at 20 pediatric hospitals in 17 states during July 1, 2021-January 17, 2022, to assess effectiveness of maternal completion of a 2-dose primary mRNA COVID-19 vaccination series during pregnancy against COVID-19 hospitalization in infants. (cdc.gov)
  • Maternal Longstanding Physical Disability and Increased Risk for Small for Gestational Age Infants: Is Prescription Opioid Use on the Causal Pathway? (sc.edu)
  • For example, early gestational age at birth predicts the two largest causes of death in premature infants: underdevelopment of mature organs and bronchopulmonary dysplasia, a chronic lung disease that damages alveolar tissue [ 1 , 2 ]. (biomedcentral.com)
  • In a study that followed preterm infants for seven years, investigators from Brigham and Women's Hospital together with collaborators at the South Australian Health and Medical Research Institute found that children who received greater quantities of maternal milk both during and after time in the neonatal intensive care unit (NICU) had greater academic achievement, higher IQs and reduced ADHD symptoms. (globalwomenshealthacademy.org)
  • Our study finds that there may be long-term neurodevelopmental benefits to providing maternal milk to preterm infants," said corresponding author Mandy Brown Belfort, MD, MPH, of the Department of Pediatric Newborn Medicine. (globalwomenshealthacademy.org)
  • These beneficial associations were stronger for infants born at the lowest gestational ages, particularly those born below 30 weeks of gestation. (globalwomenshealthacademy.org)
  • Overall, Belfort sees the team's findings as an affirmation of guidance from the American Academy of Pediatrics and World Health Organization, both of which recommend maternal milk for infants. (globalwomenshealthacademy.org)
  • Our study confirms recommended strategies for supporting parents to provide maternal milk for preterm infants," said Belfort. (globalwomenshealthacademy.org)
  • Due to the benefits of breastfeeding, the World Health Organization (WHO) in association with the United Nations Foundation (UNICEF) advocates that all women should be empowered to practice exclusive breastfeeding, and all infants should be exclusively breastfed from birth up to six months of age. (bvsalud.org)
  • If maternal diabetes is longstanding or associated with known microvascular disease, obtain a baseline maternal electrocardiogram (ECG) and echocardiogram. (medscape.com)
  • Maternal illnesses like diabetes mellitus, conditions such as iodine and folic acid deficiency, and exposure to medicines and recreational drugs including alcohol and tobacco, certain environmental chemicals, and high doses of radiation are other factors that cause birth defects. (who.int)
  • A maternal-fetal medicine (MFM) specialist is specially trained to treat women with diabetes during pregnancy. (pediatrix.com)
  • In-utero hyperglycemia exposure influences later cardiometabolic risk, although few studies include women with pre-existing type 2 diabetes (T2D) or assess maternal body mass index (BMI) as a potential confounder. (nature.com)
  • To explore the association of maternal T2D and gestational diabetes mellitus (GDM) with childhood anthropometry, and the influence of maternal BMI on these associations. (nature.com)
  • In 2021, an estimated 1,205 women died due to maternal causes in the United States. (statista.com)
  • A total of 1,205 women died of maternal causes in 2021, compared with 861 in 2020 and 754 in 2019, according to the report from Donna Hoyert, PhD, of the CDC's National Center for Health Statistics. (medpagetoday.com)
  • There are many factors that may influence childbearing age in women, although they are mostly correlations without certain causations. (wikipedia.org)
  • A variety of risk factors can make a pregnancy high-risk, including advanced maternal age, chronic health conditions, problems with a previous pregnancy and problems that develop during pregnancy. (pediatrix.com)
  • Regional security problems, low access to maternal health services, gender inequality, cultural barriers, inadequate numbers of female health staff, unequipped medical centres, adolescent pregnancy and a high illiteracy rate are factors that may threaten Afghan maternal health (1). (who.int)
  • The purpose of the study was to identify maternal HLA class Ib genetic factors associated with anti-HLA allo-immunization in pregnancy and the degree of tolerance estimated by IgG4 expression. (frontiersin.org)
  • The prevalence of atopic dermatitis (AD) in children has steadily increased over time, yet it remains largely unknown how maternal factors during pregnancy are associated with child AD. (washington.edu)
  • The detection of risk factors by a good prenatal follow-up and the regular training of the care providers for adequate and multidisciplinary care (obstetrician, intensive care nephrologist and pediatrician) of hypertensive pregnant women and their newborns can improve the maternal prognosis and fetal. (scirp.org)
  • To test whether the exposure of a child to risk factors associated with mental health adds to the prediction of child psychopathology beyond exposure to maternal depression. (cambridge.org)
  • A number of risk factors have been identified for small for gestational age and preterm birth. (springer.com)
  • One of the most common risk factors for a high-risk pregnancy is the age of the mother-to-be. (webmd.com)
  • The authors note that their study is observational - they cannot determine causality as there may be other, unaccounted factors that influence both the ability to provide maternal milk and academic achievement. (globalwomenshealthacademy.org)
  • The objectives of this study were to clarify the nutritional status of children aged 0-23 months and to identify the associated factors in rural Nicaragua. (nih.gov)
  • Specialized centers with a maternal-fetal medicine specialist can play a significant role in managing high risk pregnancies. (medscape.com)
  • Since 1995, Maternal-Fetal Medicine of Texas has provided high quality, specialized care to pregnant women by educating, counseling and managing complicated pregnancies to maximize maternal and fetal health. (pediatrix.com)
  • The care of a maternal-fetal medicine specialist can significantly contribute to the baby's health before and after birth. (pediatrix.com)
  • Our board-certified maternal-fetal medicine (MFM) specialists provide prenatal care for expectant patients with complicated or high-risk pregnancies. (pediatrix.com)
  • Women having a high-risk pregnancy should be seen more frequently for close monitoring by a maternal-fetal medicine specialist, a physician specially trained to treat high-risk pregnancies. (pediatrix.com)
  • Maternal-fetal medicine specialists are available to provide additional monitoring and comprehensive care to women with high-risk pregnancies who are hospitalized prior to delivery. (pediatrix.com)
  • Dr. Yevgeniya Pozharny, MD is a Maternal-Fetal Medicine Specialist in Brooklyn, NY. (sharecare.com)
  • Dr. Pozharny is board certified in Maternal & Fetal Medicine and accepts multiple insurance plans. (sharecare.com)
  • Dr. Liza Kunz, MD is a Maternal-Fetal Medicine Specialist in Mountain View, CA. (sharecare.com)
  • Dr. Margaret F. Carter, as a physician for Huntsville Hospital Maternal Fetal Medicine, provides medical evaluation and treatment for women whose pregnancies may have an increased risk of complications. (huntsvillehospital.org)
  • Dr. Carter is double-board certified in Maternal Fetal Medicine and OB/GYN. (huntsvillehospital.org)
  • She completed her medical school and residency training in New Orleans and her Maternal Fetal Medicine Fellowship training at the University of Texas Health Science Center in San Antonio. (huntsvillehospital.org)
  • Services provided by Huntsville Hospital Maternal Fetal Medicine are covered by most insurance plans. (huntsvillehospital.org)
  • Data regarding maternal socio-demographic and mental health were recorded. (springer.com)
  • Pregnancy involves maternal brain adaptations, but little is known about how parity influences women's brain aging trajectories later in life. (ox.ac.uk)
  • In this study, we replicated previous findings showing less apparent brain aging in women with a history of childbirths, and identified regional brain aging patterns linked to parity in 19,787 middle- and older-aged women. (ox.ac.uk)
  • A U-shaped relationship between maternal age and preterm birth was present in both years with the lowest preterm birth rate occurring among women aged 25−29 years (Table) (Figure). (cdc.gov)
  • This was an increase from 861 reported cases of maternal deaths in 2020. (statista.com)
  • As with differences by race and ethnicity, the differences in the rates between age groups were statistically significant, as were the increases in the rates between 2020 and 2021 for each age group. (medpagetoday.com)
  • In the fall semester of 2020, the MCH Catalyst Program announced its inaugural Maternal and Child Health Graduate Scholars . (sc.edu)
  • The table below shows the correlation of maternal age (mother's age) and the potential risk of human genetic abnormalities in children. (edu.au)
  • We analysed data from 8,621 European liveborn singletons in 2 population-based pregnancy cohorts (the Generation R Study, the Netherlands 2002-2006 [ n = 4,682]) and the Born in Bradford study, United Kingdom 2007-2010 [ n = 3,939]) with fetal ultrasound and birth anthropometric measures, parental smoking during pregnancy, and maternal genetic data. (plos.org)
  • The risk of miscarriage and genetic defects further increases after age 40. (webmd.com)
  • This section consists of multiple reports that the Perinatal Data Center has created in order to use data to tell a story about maternal and child health in your state. (marchofdimes.org)
  • At the same time, these risk exposures significantly increased the odds of both externalising and internalising diagnoses, over and above the influence of maternal depression. (cambridge.org)
  • Greater maternal antenatal BMI was associated with increased anthropometric measures in offspring independent of maternal glycemic status. (nature.com)
  • More attractive health education or antenatal care programmes might lead to substantial improvements in maternal and child health in this small, poor community. (nih.gov)
  • The results suggest that young maternal age (≤24 years old) is a factor associated with severe CHD phenotypes while a positive association between advanced maternal age (35-44 years old) and mild CHD phenotypes was observed. (bvsalud.org)
  • We identified ICD-10CA diagnosis codes and Canadian Classification of Interventions (CCI) procedure codes associated with severe maternal illness. (nih.gov)
  • Despite the large sample size, statistical power was insufficient to examine the association between maternal age and maternal death or very rare severe morbidities. (giuliamuraca.com)
  • National Vital Statistics System data for all live births to U.S. residents in 2007 and 2014 were analyzed for the effects of maternal age on the decline in preterm birth rates. (cdc.gov)
  • After adjusting for maternal, child, and environmental covariates, maternal metabolic syndrome classification during pregnancy was associated with children's LIT domain through direct effects of maternal metabolic health and indirect effects of cord blood markers (total effects), and COM and PSE domains via changes only in a child's cord blood markers (total indirect effects). (biomedcentral.com)
  • Relative impact of maternal depression and associated. (cambridge.org)
  • A consistent linear dose-dependent association of maternal smoking with fetal growth was observed from the early second trimester onwards, while no major growth deficit was found in women who quit smoking early in pregnancy except for a shorter FL during late gestation. (plos.org)
  • Having children later was not exceptional in the past, when families were larger and women often continued bearing children until the end of their reproductive age. (wikipedia.org)
  • Fewer than 50% of the migrant population is female and about one-third of them are of reproductive age (2-4). (who.int)
  • We investigated the associations of maternal and birth characteristics with risk of endometriosis among Swedish women of reproductive age. (lu.se)
  • The objective of this study is to quantify a child's risk of developmental vulnerability at age five, according to their mother's age at childbirth. (edu.au)
  • This statistic presents the number of maternal deaths in the United States from 2018 to 2021, by age group. (statista.com)
  • The Arnold School's Maternal and Child Health (MCH) Catalyst Program partnered with Discover UofSC 2021 to host two MCH-focused contests for participants in the annual university-wide research event. (sc.edu)
  • However, one surprising finding of the same autism research is that the younger maternal age - below 20 years - is also associated with autism spectrum disorders in the child in the future. (mana.org)
  • Advanced maternal age is associated with adverse reproductive effects such as increased risk of infertility, and that the children have chromosomal abnormalities. (wikipedia.org)
  • According to Henri Leridon, PhD, an epidemiologist with the French Institute of Health and Medical Research, of women trying to get pregnant, without using fertility drugs or in vitro fertilization: A woman's risk of having a baby with chromosomal abnormalities increases with her age. (wikipedia.org)
  • The first column shows maternal age, the second column shows the most common human chromosomal abnormality, trisomy 21 (Down syndrome), the third column shows all chromosomal abnormalities. (edu.au)
  • Advanced maternal age and risk of non-chromosomal anomalies: data from a tertiary referral hospital in Turkey [8] "The purpose of this study is to determine if there is a relationship between non-chromosomal fetal anomalies of various organ systems and advanced maternal age. (edu.au)
  • It enables the timely deployment of primary prevention interventions which aim to prevent teratogen-induced birth defects (including those caused by congenital syphilis and rubella), defects caused by iodine deficiency disorder, neural tube defects (and possibly other malformations), and maternal-age-related chromosomal disorders (e.g. (who.int)
  • Before we go on, I will say that it is absolutely true that the risk of Down Syndrome (and other chromosomal abnormalities) increases each year a woman ages as her eggs age. (howardisms.com)
  • The figure above shows birth rates among women aged 15-44 years, by maternal age group, in the United States during 1961, 2007, and 2011. (cdc.gov)
  • The maternal HLA-E*01:06 allele was significantly associated with a higher fraction of anti-HLA I immunization (20.0% vs. 4.8%, p = 0.048). (frontiersin.org)
  • Using a suite of 15 epigenetic clocks, we only found one significant relationship: advanced age on the epigenetic clock trained on leptin predicted a significantly earlier gestational age at delivery ( β = − 0.15, p = 0.009). (biomedcentral.com)
  • Maternal blood serum was screened for HLA class I and II antibodies, identification of Donor Specific Antibody (DSA), activation of complement measured by C1q and IgG4 concentrations. (frontiersin.org)
  • Detectable COVID-19 antibodies were also present in breast milk, indicating a transfer of maternal antibodies to the baby. (edu.au)
  • Infections begin once transferred maternal immunoglobulin G (IgG) antibodies have been catabolized, typically at about 6 months of age. (medscape.com)
  • Models were adjusted for potential maternal, socioeconomic, and child confounders such as maternal education, deprivation, and gestational age. (biomedcentral.com)
  • A woman's fertility peaks lasts during the twenties and first half of thirties, after which it starts to decline, with advanced maternal age causing an increased risk of female infertility. (wikipedia.org)
  • For most people, it implies that at the age of 35 or greater, the ability to have a child becomes dangerous and risky - and women who dare such a feat will need special care and special "high-risk" interventions. (howardisms.com)
  • What literature is available almost routinely refers to the age of 35 as being the time of an abrupt change in obstetric risk. (howardisms.com)
  • The concept of the arbitrary age (35 years) at which maternal risk increases should be abandoned as a myth, and the more logical concept of a sliding scale of difficulty should replace it. (howardisms.com)
  • When you look at the risk of Down Syndrome for a given age, you will find different risks depending on how far along the pregnancy is. (howardisms.com)
  • For example, many internet websites and calculators list the risk of Down Syndrome at age 35 as 1 in 350, but this is the risk at birth for a woman that age. (howardisms.com)
  • The age of the father and pregnant woman also appears to affect the child's risk of developing autism. (mana.org)
  • Maternal depression increased diagnoses of externalising and internalising disorders, but a substantial portion of these associations was explained by increased risk factor exposure (41% for externalising and 37% for internalising disorders). (cambridge.org)
  • This paper finds an association between maternal financial strain and risk of preterm birth that is as high as that for smoking. (springer.com)
  • Women who will be under age 17 or over age 35 when their baby is due are at greater risk of complications than those between their late teens and early 30s. (webmd.com)
  • To determine the impact of rurality on maternal and child health in Maine, USA, 11 years of data (2000-2010) for the state of Maine from the Pregnancy Risk Assessment Monitoring System (PRAMS) project were analyzed. (rrh.org.au)
  • There was variation in risk by age and race/ethnicity and differences by age within ethnic groups. (elsevierpure.com)
  • Average age at first childbirth has been increasing, especially in OECD countries, among which the highest average age is 32.6 years (South Korea) followed by 32.1 years (Ireland and Spain). (wikipedia.org)
  • In a number of European countries (Spain), the mean age of women at first childbirth has crossed the 30 year threshold. (wikipedia.org)
  • In the U.S., the average age of first childbirth was 26.9 in 2018. (wikipedia.org)
  • For instance, older maternal age at first childbirth is associated with higher educational attainment and income. (wikipedia.org)
  • The maternal brain: Region-specific patterns of brain aging are traceable decades after childbirth. (ox.ac.uk)
  • Effective public health strategies for further reducing preterm birth rates need to be tailored to different age groups. (cdc.gov)
  • A maternal death is defined by the World Health Organization as, "the death of a woman while pregnant or within 42 days of termination of pregnancy, irrespective of the duration and the site of the pregnancy, from any cause related to or aggravated by the pregnancy or its management, but not from accidental or incidental causes. (statista.com)
  • There is limited evidence from human studies on how maternal cardiometabolic health during pregnancy affects a child's cognitive and behavioural development. (biomedcentral.com)
  • Giving birth at a young age is common, adversely affecting maternal health and child undernutrition. (medrxiv.org)
  • The data in the report "send a resounding message that maternal health and evidence‐based efforts to eliminate racial health inequities need to be, and remain, a top public health priority," said Iffath Abbasi Hoskins, MD, president of the American College of Obstetricians and Gynecologists (ACOG), in a statement. (medpagetoday.com)
  • Just as concerning are worsening racial health inequities and the fact that pregnant and postpartum Black people continue to make up a disproportionate number of maternal deaths at growing and alarming rates. (medpagetoday.com)
  • Nonetheless, the CDC's latest report confirms that additional action is needed to stem the rise in maternal deaths and mitigate maternal health disparities. (medpagetoday.com)
  • Led by epidemiology professor Jihong Liu , with support from epidemiology clinical associate professor Linda Hazlett , this program works with approximately 40 maternal and child health experts from across the Arnold School to bolster programming and training opportunities in this area. (sc.edu)
  • 130 g/L in the third trimester should be paid great attention to in the practice of maternal and child health care. (lstmed.ac.uk)
  • These results highlight areas where focused pre-pregnancy and prenatal education may improve maternal and child health in rural Maine. (rrh.org.au)
  • The corresponding paternal age effect is less pronounced. (wikipedia.org)
  • This study investigated the effect of paternal and maternal silent coeliac disease on birthweight and gestational age in newborns. (uwi.edu)
  • In other words, each year a woman ages, pregnancy risks go up slightly but there is no vast cliff waiting for her at age 35. (howardisms.com)
  • In the third trimester, maternal hemoglobin concentration was associated with birth weight in an inverted U-shaped curve and with the risks of LBW and SGA in extended U-shaped curves. (lstmed.ac.uk)
  • We hypothesize that BM antioxidants are adapted to gestational age and are negatively influenced by maternal age. (mdpi.com)
  • Contrary to expectation, maternal distress in Pakistani women was negatively associated with SGA (OR 0.65: CI 0.48-0.88). (springer.com)
  • The parents of premature and/or small for gestational age babies born with coeliac disease-specific antigens were investigated. (uwi.edu)
  • In this context, we aimed to measure macronutrient content of very preterm milk and to identify changes associated with time and maternal, gestational and neonatal characteristics. (nature.com)
  • We also found that an estimated 26% of the association between maternal smoking and early-onset endometriosis could be explained by birthweight-for-gestational age. (lu.se)
  • Preterm birth rates declined for all age groups and overall from 10.41% to 9.54% of live births. (cdc.gov)
  • For women under 25, the rate was 20.4 deaths per 100,000 live births, compared with 31.3 for women ages 25-39 and 138.5 for those ages 40 and over. (medpagetoday.com)
  • The rate for women ages 40 and over was 6.8 times higher than the rate for those under age 25. (medpagetoday.com)
  • In the USA, the average age at which women bore their first child advanced from 21.4 years old in 1970 to 26.9 in 2018. (wikipedia.org)
  • Mean maternal age increased from 27.4 years to 28.3 years. (cdc.gov)
  • From 2007 to 2014, the birth rate for females aged 15-19 years declined 42%, from 41.5 to 24.2 per 1,000 females. (cdc.gov)
  • At the age of M = 4.0 years, children's ToM abilities were assessed using content-false-belief and location-false-belief tasks. (uni-muenchen.de)
  • Given the increase in maternal age over recent years, it is important to study the CHD prevalence by maternal age . (bvsalud.org)
  • Further subgroup analyses were undertaken within four maternal age -bands ≤24, 25-29, 30-34 and 35-44 years. (bvsalud.org)
  • During 1961-2011, birth rates decreased for all women aged 15-44 years. (cdc.gov)
  • 35 years, with rates for women aged 20-24 years (85.3 per 1,000 population) and those aged 15-19 years (31.3) reaching historic lows. (cdc.gov)
  • The birth rate for women aged 25-29 years decreased 9% (to 107.2), and the rate for women aged 30-34 years decreased 6% (to 96.5). (cdc.gov)
  • The birth rate for women aged 35-39 years was unchanged (47.2), and the rate for women aged 40-44 years increased 10% (to 10.3). (cdc.gov)
  • Wave 1 follow-up included 423 children, aged 1.5-5 years (median follow-up age 2.5 years). (nature.com)
  • Findings from this study suggest no association between prenatal SLEs and AD in children aged approximately 4-6 years, although larger longitudinal studies with enhanced case definition and higher variability of SLE experience may more fully inform this question. (washington.edu)
  • and DSM-IV-based externalising and internalising diagnoses were evaluated when the children were 7.5 years of age. (cambridge.org)
  • Our findings emphasize the importance of providing support for initiating and sustaining lactation because maternal milk at this early age can provide benefits years later. (globalwomenshealthacademy.org)
  • This study describes the prevalence of clinical conditions that are associated with pregnancy, stratified at age 35 years, and by ethnicity (black, white, Hispanic, other). (elsevierpure.com)
  • After this period, the children should continue to be breastfed along with complementary foods up to the age of two years or more [4]. (bvsalud.org)
  • Confirmation of gestational age is based on physical and neurologic characteristics. (medscape.com)
  • It is unknown how changes in the maternal age distribution in the United States have affected preterm birth rates. (cdc.gov)
  • CDC used birth data to assess the relative contributions of changes in the maternal age distribution and in age-specific preterm birth rates to the overall decrease in preterm birth rates. (cdc.gov)
  • The preterm birth rate declined in all age groups. (cdc.gov)
  • The sum of the two components across the age groups equaled the total preterm birth rate difference ( 4 ). (cdc.gov)
  • The current study is in line with this important scientific theme by investigating a role of maternal HLA class Ib polymorphisms in pregnancy allo-immunization. (frontiersin.org)
  • The strongest effect was found in the accumbens-a key region in the mesolimbic reward system, which plays an important role in maternal behavior. (ox.ac.uk)
  • Maternal WSD reduced insulin-stimulated glucose uptake and impaired insulin signaling at the level of Akt phosphorylation in fetal muscle. (diabetesjournals.org)
  • In juvenile offspring, insulin-stimulated glucose uptake was similarly reduced by both maternal and postweaning WSD and corresponded to modest reductions in insulin-stimulated Akt phosphorylation relative to controls. (diabetesjournals.org)