Lorazepam
Anti-Anxiety Agents
Diazepam
Alprazolam
United States Federal Trade Commission
Hypnotics and Sedatives
Benzodiazepines
Medazepam
Status Epilepticus
Fraud
Lorazepam for the prevention of recurrent seizures related to alcohol. (1/211)
BACKGROUND AND METHODS: Alcohol abuse is one of the most common causes of seizures in adults. In a randomized, double-blind study, we compared lorazepam with placebo for the prevention of recurrent seizures related to alcohol. Over a 21-month period, we studied consecutive patients with chronic alcohol abuse who were at least 21 years of age and who presented to the emergency departments of two hospitals in Boston after a witnessed, generalized seizure. The patients were randomly assigned to receive either 2 mg of lorazepam in 2 ml of normal saline or 4 ml of normal saline intravenously and then observed for six hours. The primary end point was the occurrence of a second seizure during the observation period. RESULTS: Of the 229 patients who were initially evaluated, 186 met the entry criteria. In the lorazepam group, 3 of 100 patients (3 percent) had a second seizure, as compared with 21 of 86 patients (24 percent) in the placebo group (odds ratio for seizure with the use of placebo, 10.4; 95 percent confidence interval, 3.6 to 30.2; P<0.001). Forty-two percent of the placebo group were admitted to the hospital, as compared with 29 percent of the lorazepam group (odds ratio for admission, 2.1; 95 percent confidence interval, 1.1 to 4.0; P=0.02). Seven patients in the placebo group and one in the lorazepam group were transported to an emergency department in Boston with a second seizure within 48 hours after hospital discharge. CONCLUSIONS: Treatment with intravenous lorazepam is associated with a significant reduction in the risk of recurrent seizures related to alcohol. (+info)Measuring reproducibility of regional brain metabolic responses to lorazepam using statistical parametric maps. (2/211)
Statistical parametric mapping (SPM) is a method for localizing differences in brain activation patterns without the need for anatomic predefined constraints. The purpose of this study was to assess the reproducibility of the patterns of activation obtained with SPM for baseline measures and for metabolic changes in response to lorazepam on a test-retest design. The results were compared with those we previously published using region-of-interest (ROI) methods. METHODS: Sixteen healthy right-handed men were scanned twice with PET and [18F]fluorodeoxyglucose (FDG): before placebo and before lorazepam (30 microg/kg). The same double FDG procedure was repeated 6-8 wk later to assess test-retest reproducibility. Image datasets were analyzed by using SPM95 software. Difference images between baseline and lorazepam were compared for the first and second evaluations, both for relative decreases as well as increases in metabolism. Significance level was systematically varied to P < 0.001, P < 0.01 and P < 0.05. RESULTS: There were no differences in the baseline SPM maps obtained for the first and second evaluations. SPM showed similar, although not identical, differences in response to lorazepam between the two evaluations. Both evaluations showed significant decreases in occipital cortex (9.7% and 10%) and significant relative increases in left temporal pole (6.8% and 10.4%). However, the second evaluation showed a decrease in the left frontal cortex (areas 6 and 8), which was not present in the first evaluation. The results were very similar to those we had obtained with ROI methods, except for the activation in the left temporal pole, which we had not observed with ROI analyses. CONCLUSION: Although the overall pattern of lorazepam-induced activation depicted by SPM was reproducible in pattern and magnitude, there were some differences that included a left frontal area of deactivation during the second but not the first evaluation. Results with SPM are similar to those with the ROI method, and, because it systematically analyses the whole brain, SPM can uncover patterns not seen with the ROI method. (+info)Drug discrimination analysis of partial agonists at the benzodiazepine site. I. Differential effects of U-78875 across training conditions in baboons and rats. (3/211)
The benzodiazepine receptor ligand U-78875 [3-(5-cyclopro pyl-1,2, 4-oxadiazol-3-yl)-5-(1-methylethyl)imidazol(1, 5-a)quinoxalin-4(5H)-o-ne] was studied in rats trained to discriminate i.p. 1.0 mg/kg lorazepam, 1.0 mg/kg diazepam, or 10 mg/kg pentobarbital, and baboons trained to discriminate oral 1.8 mg/kg lorazepam or 10 mg/kg pentobarbital. U-78875 doses were 0.01 to 10 mg/kg i.p. in rats and 0.32 to 56 mg/kg orally in baboons. U-78875 occasioned drug-appropriate responding in pentobarbital-trained (ED50 = 1.8 mg/kg) and diazepam-trained (ED50 = 0.056 mg/kg) rats, but it occurred in only one pentobarbital-trained baboon and not in the majority of lorazepam-trained baboons or rats. In baboons that generalized to U-78875, discriminative effects were antagonized by flumazenil. The interaction of U-78875 with pentobarbital, diazepam, and lorazepam revealed further differences in its behavioral effects. U-78875 potentiated the effects of pentobarbital, even in baboons that did not generalize to U-78875, but U-78875 had little effect in combination with diazepam. In lorazepam-trained animals that did not generalize to it, U-78875 antagonized lorazepam's effects, but U-78875 neither antagonized nor potentiated lorazepam in animals that did generalize to U-78875. Thus, although U-78875 generally functioned as a benzodiazepine agonist in pentobarbital- and diazepam-trained animals, its unique effects in lorazepam-trained animals appear to reflect its in vitro profile as a partial agonist. (+info)Effects of a benzodiazepine, lorazepam, on motion integration and segmentation: an effect on the processing of line-ends? (4/211)
Previous studies have shown that the perceptual integration of component motions distributed across space is inhibited whenever segmentation cues, such as line-ends, are salient. Herein, we investigate to what extent enhanced inhibition induced by lorazepam, a benzodiazepine facilitating the fixation of GABA on GABAA receptors, modifies the balance between motion integration and motion segmentation at the behavioural level. Motion integration was tested in 16 healthy volunteers taking a single and oral dose of either placebo or lorazepam (0.038 mg kg-1). The stimulus consisted of an outlined diamond presented behind four, otherwise invisible, apertures and translating along a circular trajectory (Lorenceau & Shiffrar (1992). Vision Research, 32, 263-273). Under these conditions, recovering the global diamond direction requires the integration of the component motions available within each aperture. The observers were asked to discriminate the global, clockwise or counter-clockwise, diamond direction under difficult--at high luminance contrasts--or easy--at low luminance contrasts--conditions. Overall, reaction times and error rates increased in the lorazepam group as compared to the placebo group, suggesting strong non-specific effects. However, the changes in performance in the lorazepam group are not homogeneous across conditions, suggesting that lorazepam also induces specific effects that modulate the integration/segmentation balance. Additional experiments performed with visible apertures or visible diamond vertices indicate that the effects of lorazepam are unlikely to reflect a deficit of motion processing or motion integration mechanisms since performance is only slightly impaired in the lorazepam as compared to the placebo group under these conditions. These results suggest that lorazepam might specifically modulate the saliency of line-ends, presumably because processing these features involves inhibitory mechanisms using GABA as a neuromediator, and in turn modify the balance between motion integration and segmentation. (+info)Modification of the pharmacokinetics of high-dose cyclophosphamide and cisplatin by antiemetics. (5/211)
Interpatient variability in exposure to certain chemotherapy agents can influence patient outcome, particularly with high-dose chemotherapy. We evaluated the possibility of a pharmacokinetic (PK) drug-drug interaction between the antiemetic agents and high-dose cyclophosphamide, cisplatin and BCNU (CPA/cDDP/BCNU). Twenty-three self-selected patients treated with high-dose CPA/cDDP/BCNU followed by autologous hematopoietic progenitor cell support (AHPCS) received ondansetron, lorazepam and diphenhydramine as antiemetics. PK parameters for each chemotherapeutic drug in the regimen were compared with those of 129 patients who received exactly the same chemotherapy but an antiemetic regimen substituting prochlorperazine for ondansetron. In addition, we performed a review of the English literature for reported drug-drug interactions between antiemetics and chemotherapy agents that led to modifications in any PK parameters of the chemotherapy agent. Our retrospective study showed that the mean area under the curve (AUC) for both cyclophosphamide (76,600 vs 90,600 microg/ml/min, P=0.001) and cisplatin (525 vs 648 microg/ml/min, P = 0.01) were significantly lower in the ondansetron group when compared with the prochlorperazine group. The AUC for BCNU was not significantly different in both groups (544 vs 677, P = 0.43). We found only one report of modifications of the PK parameters of high-dose chemotherapy agents due to drug-drug interactions with the most commonly used antiemetics in a review of the English literature between 1966 and 1995. We concluded that the AUC of high-dose cyclophosphamide and cisplatin are significantly lower when ondansetron, as opposed to prochlorperazine, is used as the antiemetic. The small sample size and heterogeneity of this group of patients precludes any outcome analysis of pharmacodynamic endpoints such as toxicity or antitumor effect. Nevertheless, the potential for interactions between antiemetics and chemotherapy agents should be taken into account when using different high-dose chemotherapy regimens. (+info)Safety and efficacy of a continuous infusion, patient controlled anti-emetic pump to facilitate outpatient administration of high-dose chemotherapy. (6/211)
We evaluated the combination of diphenhydramine, lorazepam, and dexamethasone delivered as a continuous i.v. infusion via an ambulatory infusion pump with patient-activated intermittent dosing (BAD pump) for prevention of acute and delayed nausea/vomiting in patients receiving high-dose chemotherapy (HDC) for peripheral blood progenitor cell (PBPC) mobilization (MOB) or prior to autologous PBPC rescue. The BAD pump was titrated to patient response and tolerance, and continued until the patient could tolerate oral anti-emetics. Forty-four patients utilized the BAD pump during 66 chemotherapy courses, 34 (52%) for MOB and 32 (48%) for HDC with autologous PBPC rescue. The median number of days on the BAD pump during MOB and HDC was 3 (1-6) and 9 (2-19) days, respectively. Complete overall or complete emesis control occurred on 94% of MOB and 89% of HDC treatment days during chemotherapy administration and 72% and 43%, respectively, following chemotherapy administration. Eighty-three percent of MOB and 55% of HDC treatment days were associated with no nausea. While on the BAD pump, no patient experienced severe toxicity or required hospitalization for management of nausea/vomiting. The BAD pump was safe and effective in minimizing nausea and vomiting associated with HDC, and thus, eliminated the need for hospitalization for management of chemotherapy-induced nausea and vomiting. (+info)Outpatient detoxification of the addicted or alcoholic patient. (7/211)
Outpatient detoxification of patients with alcohol or other drug addiction is being increasingly undertaken. This type of management is appropriate for patients in stage I or stage II of withdrawal who have no significant comorbid conditions and have a support person willing to monitor their progress. Adequate dosages of appropriate substitute medications are important for successful detoxification. In addition, comorbid psychiatric, personality and medical disorders must be managed, and social and environmental concerns need to be addressed. By providing supportive, nonjudgmental, yet assertive care, the family physician can facilitate the best possible chance for a patient's successful recovery. (+info)Effect of potential confounding factors on the thrombolysis in myocardial infarction (TIMI) trial frame count and its reproducibility. (8/211)
BACKGROUND: The potential factors that introduce variability into TIMI frame count (TFC) have not been systematically investigated. The goal of this study was to determine if nitrate use, dye injection rate, catheter size, the phase of the cardiac cycle in which dye is injected, or heart rate affect the TFC and to investigate the reproducibility of the TFC. METHODS AND RESULTS: The dye injection rate was increased 1 mL/s, and angiography was repeated. A coronary angiogram was taken first with an 8F catheter and then with a 6F catheter. After taking angiograms, intracoronary nitrate was given to the patient, and the second angiography was performed. Basal heart rate was increased 20 beats/min, and angiography was repeated. Dye injection was performed at the beginning of systole and diastole. The TFC was not significantly changed by increasing the dye injection rate (P=0.467) or by changing catheter size (P=0.693). Nitrate administration significantly increased the TFC from 26.4+/-11.9 to 32.8+/-13.3 frames (P<0.001). Dye injection at the beginning of diastole significantly decreased the TFC from 30.1+/-8.8 to 24.4+/-7.9 frames (P<0.001) for the left coronary artery and from 24.16+/-4.49 to 21. 24+/-4.45 frames (P<0.001) for the right coronary artery. Increasing heart rate significantly decreased the TFC from 30.4+/-6.1 to 25. 3+/-7.2 frames (P<0.001). Intraobserver and interobserver reproducibility of the TFC was good (mean difference, 1.33+/-1.24 and 2.57+/-1.72 frames, respectively). CONCLUSIONS: Nitrate use, heart rate, and the phase of the cardiac cycle in which dye is injected had significant effects on the TFC. Therefore, studies comparing TFC need to consider these factors, and the use of nitrates should be either standardized or randomized. (+info)Lorazepam is a medication that belongs to a class of drugs known as benzodiazepines. Medically, it is defined as a prescription drug used for the treatment of anxiety disorders, short-term relief of symptoms of anxiety or anxiety associated with depressive symptoms. It can also be used for the treatment of insomnia, seizure disorders, and alcohol withdrawal. Lorazepam works by affecting chemicals in the brain that may become unbalanced and cause anxiety or other symptoms.
It is important to note that lorazepam can be habit-forming and should only be used under the supervision of a healthcare provider. Misuse of this medication can lead to serious risks, including addiction, overdose, or death.
Anti-anxiety agents, also known as anxiolytics, are a class of medications used to manage symptoms of anxiety disorders. These drugs work by reducing the abnormal excitement in the brain and promoting relaxation and calmness. They include several types of medications such as benzodiazepines, azapirone, antihistamines, and beta-blockers.
Benzodiazepines are the most commonly prescribed anti-anxiety agents. They work by enhancing the inhibitory effects of a neurotransmitter called gamma-aminobutyric acid (GABA) in the brain, which results in sedative, hypnotic, anxiolytic, anticonvulsant, and muscle relaxant properties. Examples of benzodiazepines include diazepam (Valium), alprazolam (Xanax), lorazepam (Ativan), and clonazepam (Klonopin).
Azapirones are a newer class of anti-anxiety agents that act on serotonin receptors in the brain. Buspirone (Buspar) is an example of this type of medication, which has fewer side effects and less potential for abuse compared to benzodiazepines.
Antihistamines are medications that are primarily used to treat allergies but can also have anti-anxiety effects due to their sedative properties. Examples include hydroxyzine (Vistaril, Atarax) and diphenhydramine (Benadryl).
Beta-blockers are mainly used to treat high blood pressure and heart conditions but can also help manage symptoms of anxiety such as rapid heartbeat, tremors, and sweating. Propranolol (Inderal) is an example of a beta-blocker used for this purpose.
It's important to note that anti-anxiety agents should be used under the guidance of a healthcare professional, as they can have side effects and potential for dependence or addiction. Additionally, these medications are often used in combination with psychotherapy and lifestyle modifications to manage anxiety disorders effectively.
Diazepam is a medication from the benzodiazepine class, which typically has calming, sedative, muscle relaxant, and anticonvulsant properties. Its medical uses include the treatment of anxiety disorders, alcohol withdrawal syndrome, end-of-life sedation, seizures, muscle spasms, and as a premedication for medical procedures. Diazepam is available in various forms, such as tablets, oral solution, rectal gel, and injectable solutions. It works by enhancing the effects of a neurotransmitter called gamma-aminobutyric acid (GABA) in the brain, which results in the modulation of nerve impulses in the brain, producing a sedative effect.
It is important to note that diazepam can be habit-forming and has several potential side effects, including drowsiness, dizziness, weakness, and impaired coordination. It should only be used under the supervision of a healthcare professional and according to the prescribed dosage to minimize the risk of adverse effects and dependence.
Alprazolam is a medication that belongs to a class of drugs called benzodiazepines. It works by increasing the activity of gamma-aminobutyric acid (GABA), a neurotransmitter in the brain that has a calming effect. Alprazolam is used to treat anxiety disorders, panic disorder, and anxiety associated with depression.
The medical definition of Alprazolam is:
"A triazolo analog of the benzodiazepine class of central nervous system-active compounds. It has antianxiety, anticonvulsant, muscle relaxant, and sedative properties. Alprazolam is used in the management of anxiety disorders, panic disorder, and anxiety associated with depression."
It's important to note that Alprazolam can be habit-forming and should only be taken under the supervision of a healthcare provider. It can also cause side effects such as drowsiness, dizziness, and impaired coordination. If you have any questions about Alprazolam or are considering taking it, it's important to speak with your doctor first.
The Federal Trade Commission (FTC) is not a medical organization or agency, but rather it is a consumer protection agency in the United States government. The FTC is responsible for protecting consumers and promoting competition by preventing anticompetitive, deceptive, and unfair business practices. While the FTC does not provide medical definitions, it may be involved in investigating and taking enforcement actions related to false or misleading health claims made by businesses.
Hypnotics and sedatives are classes of medications that have depressant effects on the central nervous system, leading to sedation (calming or inducing sleep), reduction in anxiety, and in some cases, decreased awareness or memory. These agents work by affecting the neurotransmitter GABA (gamma-aminobutyric acid) in the brain, which results in inhibitory effects on neuronal activity.
Hypnotics are primarily used for the treatment of insomnia and other sleep disorders, while sedatives are often prescribed to manage anxiety or to produce a calming effect before medical procedures. Some medications can function as both hypnotics and sedatives, depending on the dosage and specific formulation. Common examples of these medications include benzodiazepines (such as diazepam and lorazepam), non-benzodiazepine hypnotics (such as zolpidem and eszopiclone), barbiturates, and certain antihistamines.
It is essential to use these medications under the guidance of a healthcare professional, as they can have potential side effects, such as drowsiness, dizziness, confusion, and impaired coordination. Additionally, long-term use or high doses may lead to tolerance, dependence, and withdrawal symptoms upon discontinuation.
Temazepam is a benzodiazepine medication that is primarily used for the treatment of insomnia. It has a depressant effect on the central nervous system and helps to slow down brain activity, allowing for relaxation and promoting sleep. Temazepam works by binding to specific receptors in the brain called GABA-A receptors, which are involved in regulating nerve impulses in the brain. This action increases the activity of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), resulting in sedative, hypnotic, anxiolytic, anticonvulsant, and muscle relaxant effects.
Temazepam is available in immediate-release and controlled-release formulations, with the former typically taken just before bedtime and the latter taken at bedtime to help people stay asleep throughout the night. It is important to note that temazepam can be habit-forming and should only be used under the supervision of a healthcare provider. Common side effects include drowsiness, dizziness, weakness, and coordination problems.
Benzodiazepines are a class of psychoactive drugs that have been widely used for their sedative, hypnotic, anxiolytic, anticonvulsant, and muscle relaxant properties. They act by enhancing the inhibitory effects of gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the central nervous system.
Benzodiazepines are commonly prescribed for the treatment of anxiety disorders, insomnia, seizures, and muscle spasms. They can also be used as premedication before medical procedures to produce sedation, amnesia, and anxiolysis. Some examples of benzodiazepines include diazepam (Valium), alprazolam (Xanax), clonazepam (Klonopin), lorazepam (Ativan), and temazepam (Restoril).
While benzodiazepines are effective in treating various medical conditions, they can also cause physical dependence and withdrawal symptoms. Long-term use of benzodiazepines can lead to tolerance, meaning that higher doses are needed to achieve the same effect. Abrupt discontinuation of benzodiazepines can result in severe withdrawal symptoms, including seizures, hallucinations, and anxiety. Therefore, it is important to taper off benzodiazepines gradually under medical supervision.
Benzodiazepines are classified as Schedule IV controlled substances in the United States due to their potential for abuse and dependence. It is essential to use them only as directed by a healthcare provider and to be aware of their potential risks and benefits.
Medazepam is a benzodiazepine medication that is primarily used for the treatment of anxiety disorders. It works by enhancing the activity of gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits the activity of certain neurons in the brain, resulting in sedative, hypnotic, anxiolytic, anticonvulsant, and muscle relaxant properties.
Medazepam is available in various forms, including tablets and injectable solutions, and is typically prescribed for short-term use due to the risk of dependence and tolerance. Common side effects include drowsiness, dizziness, weakness, and unsteadiness. It may also cause cognitive impairment, memory problems, and behavioral changes in some individuals.
Like all benzodiazepines, medazepam should be used with caution and only under the supervision of a healthcare provider. It is contraindicated in patients with acute narrow-angle glaucoma, severe respiratory depression, sleep apnea, and known sensitivity to benzodiazepines. Elderly patients and those with liver or kidney disease may require lower doses due to altered drug metabolism and elimination.
It is important to note that medazepam and other benzodiazepines can be habit-forming and should not be stopped abruptly, as this can lead to withdrawal symptoms such as seizures, tremors, and anxiety. Instead, doses should be gradually tapered under the guidance of a healthcare provider.
Status epilepticus is a serious and life-threatening medical condition characterized by an ongoing seizure activity or a series of seizures without full recovery of consciousness between them, lasting for 30 minutes or more. It is a neurological emergency that requires immediate medical attention to prevent potential complications such as brain damage, respiratory failure, or even death.
The condition can occur in people with a history of epilepsy or seizure disorders, as well as those without any prior history of seizures. The underlying causes of status epilepticus can vary and may include infection, trauma, stroke, metabolic imbalances, toxins, or other medical conditions that affect the brain's normal functioning. Prompt diagnosis and treatment are crucial to prevent long-term neurological damage and improve outcomes in patients with this condition.
In the context of medical law and ethics, fraud refers to a deliberate and intentional deception or misrepresentation of facts, motivated by personal gain, which is made by a person or entity in a position of trust, such as a healthcare professional or organization. This deception can occur through various means, including the provision of false information, the concealment of important facts, or the manipulation of data.
Medical fraud can take many forms, including:
1. Billing fraud: This occurs when healthcare providers submit false claims to insurance companies or government programs like Medicare and Medicaid for services that were not provided, were unnecessary, or were more expensive than the services actually rendered.
2. Prescription fraud: Healthcare professionals may engage in prescription fraud by writing unnecessary prescriptions for controlled substances, such as opioids, for their own use or to sell on the black market. They may also alter prescriptions or use stolen identities to obtain these drugs.
3. Research fraud: Scientists and researchers can commit fraud by manipulating or falsifying data in clinical trials, experiments, or studies to support predetermined outcomes or to secure funding and recognition.
4. Credentialing fraud: Healthcare professionals may misrepresent their qualifications, licenses, or certifications to gain employment or admitting privileges at healthcare facilities.
5. Identity theft: Stealing someone's personal information to obtain medical services, prescription medications, or insurance benefits is another form of medical fraud.
Medical fraud not only has severe legal consequences for those found guilty but also undermines the trust between patients and healthcare providers, jeopardizes patient safety, and contributes to rising healthcare costs.
Oxazepam is a benzodiazepine medication that is primarily used to treat anxiety disorders and symptoms such as sleeplessness and irritability. It works by enhancing the activity of gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits the activity of certain neurons in the brain, producing a calming effect.
In medical terms, oxazepam can be defined as follows:
Oxazepam is a Schedule IV controlled substance, indicating that it has a potential for abuse and dependence. It is available in tablet form and is typically taken two to four times per day. Common side effects of oxazepam include drowsiness, dizziness, and weakness. More serious side effects can include memory problems, confusion, and difficulty breathing.
It's important to note that oxazepam should only be used under the supervision of a healthcare provider, as it can have significant risks and interactions with other medications. It is not recommended for use in pregnant women or those with a history of substance abuse.
Psychomotor agitation is a state of increased physical activity and purposeless or semi-purposeful voluntary movements, usually associated with restlessness, irritability, and cognitive impairment. It can be a manifestation of various medical and neurological conditions such as delirium, dementia, bipolar disorder, schizophrenia, and substance withdrawal. Psychomotor agitation may also increase the risk of aggressive behavior and physical harm to oneself or others. Appropriate evaluation and management are necessary to address the underlying cause and alleviate symptoms.
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Ativan18
- Lorazepam, sold under the brand name Ativan among others, is a benzodiazepine medication. (wikipedia.org)
- Lorazepam oral tablets are also available as a brand-name version called Ativan . (medicalnewstoday.com)
- Lorazepam injection also has a brand-name version called Ativan. (medicalnewstoday.com)
- Ativan tablet is the brand-name medication that lorazepam oral tablet is based on. (medicalnewstoday.com)
- If you're interested in using Ativan tablet instead of lorazepam oral tablet, talk with your doctor. (medicalnewstoday.com)
- Lorazepam , sold under the brand name Ativan among others, is a benzodiazepine medication often used to treat anxiety disorders . (wn.com)
- With shortest-acting being Lorazepam ( ativan ), then Alprazolam ( xanax ) , then Clonazepam ( klonopin ), then diazepam ( valium ) which can have half-life of up to 100 hours. (healthtap.com)
- Is it ok to take ativan (lorazepam) in place of my klonopin/xanax until i can get my regular prescription filled?I hope you can see all the meds i take on here. (healthtap.com)
- Has anybody successfully tapered off of lorazepam (Ativan)? (mayoclinic.org)
- Lorazepam (trade name Ativan or Tavor ) is a depressant substance of the benzodiazepine class. (psychonautwiki.org)
- The generic name of ativan is Lorazepam. (opioidsmedshop.com)
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- Lorazepam, often endorsed as Ativan, exerts its influence as a central nervous system drug. (ivchost3.com)
- Ativan (Lorazepam) 1mg relieves symptoms of anxiety such as nervousness, rapid breathing, increased heart rate, excessive sweating, trembling, weakness or lack of concentration. (rxdirectmeds.com)
Benzodiazepines8
- In the US, the FDA advises against use of benzodiazepines such as lorazepam for longer than four weeks. (wikipedia.org)
- because of gradual tolerance to their anti-seizure effects, benzodiazepines such as lorazepam are not considered first-line therapies. (wikipedia.org)
- Among benzodiazepines, lorazepam has possible physical addiction potential. (wn.com)
- Study looked at anxiety medications taken during cancer treatment Highlights Benzodiazepines can relieve symptoms of anxiety, insomnia and seizures Lorazepam use showed shorter progression-free survival May activate protein that boosts cytokine response, promotes inflammation. (wn.com)
- Lorazepam is thought to have a relatively high affinity for GABA receptors compared to other benzodiazepines, which may also explain its marked amnesic effects. (psychonautwiki.org)
- Lorazepam belongs to a family of medications known as benzodiazepines. (lifemedspharmacy.uk)
- Lorazepam is from the class of meds which is called as benzodiazepines. (buyprescriptionz.com)
- With wide safety margins and few contraindications, the benzodiazepines most commonly used by dentists are diazepam, as a mild sedation-inducing anxiolytic, midazolam, to induce sleep and amnesia, and alprazolam, lorazepam, and triazolam, each with their appropriate properties and preferred dosages. (bvsalud.org)
Dosage4
- The cognitive effects of lorazepam can be broken down into several components which progressively intensify proportional to dosage. (psychonautwiki.org)
- What is the dosage of Lorazepam? (lifemedspharmacy.uk)
- The Apo Lorazepam dosage of this medication depends on what it is used for. (apomio.es)
- Embrace the prescribed dosage and instructions offered by healthcare mavens to tread the path of responsible Lorazepam consumption. (ivchost3.com)
Interactions3
- Are they any interactions with lorazepam and domperidone? (infantrisk.com)
- No interactions with lorazepam and domperidone that I am aware of. (infantrisk.com)
- RESULTS: The clinical preference for lorazepam can be attributed to its simpler metabolism with no active metabolites, better suitability for patients with less severe hepatic and renal impairment, less risk of adverse reactions, fewer drug-drug interactions, and greater desirability for special populations. (bvsalud.org)
Tablets11
- Lorazepam oral tablets can be used in adults and children ages 12 years and older. (medicalnewstoday.com)
- This article addresses only lorazepam oral tablets. (medicalnewstoday.com)
- Yes, lorazepam oral tablets are classified as a Schedule IV controlled substance. (medicalnewstoday.com)
- For information about the effectiveness of lorazepam oral tablets, see the " Lorazepam oral tablet uses " section below. (medicalnewstoday.com)
- Lorazepam oral tablets can cause mild or serious side effects. (medicalnewstoday.com)
- The following lists contain some of the key side effects that may occur while taking lorazepam oral tablets. (medicalnewstoday.com)
- For more information about the possible side effects of lorazepam oral tablets, talk with your doctor or pharmacist. (medicalnewstoday.com)
- If you would like to notify the FDA about a side effect you've had with lorazepam oral tablets, you can do so through MedWatch . (medicalnewstoday.com)
- Serious side effects from lorazepam oral tablets can occur. (medicalnewstoday.com)
- Store lorazepam tablets at room temperature, protect from light and moisture, and keep them out of the reach of children. (medbroadcast.com)
- It is important to note that you should never chew, break, or crush Lorazepam tablets as this can affect how the medication is absorbed into the body. (lifemedspharmacy.uk)
Sedation5
- Lorazepam is sometimes used as an alternative to midazolam in palliative sedation. (wikipedia.org)
- Lorazepam is sometimes used as an alternative to haloperidol when there is the need for rapid sedation of violent or agitated individuals, but haloperidol plus promethazine is preferred due to better effectiveness and due to lorazepam's adverse effects on respiratory function. (wikipedia.org)
- Lorazepam is used for the short-term treatment of anxiety , trouble sleeping , acute seizures including status epilepticus , sedation of people in hospital, as well as sedation of aggressive patients. (wn.com)
- Lorazepam is used for the short-term treatment of anxiety , insomnia , acute seizures , and the sedation of hospitalized patients. (psychonautwiki.org)
- They often are combined in the same syringe with a benzodiazepine (eg, lorazepam, diazepam) for better sedation and anxiolysis and less dystonia or akathisia. (medscape.com)
Intensol1
- Lorazepam Intensol Oral is medication that used to treat anxiety. (anxietymedication.org)
Injectable lorazepam4
- Injectable lorazepam can be used as an initial treatment for the control of prolonged seizures ( status epilepticus ). (medbroadcast.com)
- The dose of injectable lorazepam for seizures is based on body weight and given by a trained health care provider in a hospital. (medbroadcast.com)
- For delayed seizures, the injectable Lorazepam can be spent as an underlying treatment. (buyprescriptionz.com)
- CONCLUSIONS: Our goal is to aid clinicians in safely and effectively prescribing midazolam during the shortage of injectable lorazepam so that patients are provided the same effects and benefits. (bvsalud.org)
Seizures2
- Lorazepam is more effective than diazepam and intravenous phenytoin in the treatment of status epilepticus and has a lower risk of continuing seizures that might require additional medication. (wikipedia.org)
- Lorazepam reduces anxiety , interferes with new memory formation , reduces agitation , induces sleep , treats seizures , treats nausea and vomiting , and relaxes muscles . (wn.com)
Anxiety disorders4
- Lorazepam is FDA-approved for the short-term relief of anxiety symptoms related to anxiety disorders and anxiety associated with depressive symptoms such as anxiety-associated insomnia. (itopmeds.com)
- Lorazepam is used to treat anxiety disorders. (opioidsmedshop.com)
- Lorazepam finds its function in undertaking anxiety disorders, about generalized anxiety disorder (GAD), social anxiety disorder, and panic disorder. (ivchost3.com)
- Lorazepam is a prescription medicine used to treat anxiety disorders such as generalized anxiety disorder (excessive worry or restlessness), obsessive compulsive disorder (OCD), panic attacks and social phobias. (rxdirectmeds.com)
Medication8
- Lorazepam oral tablet is a prescription medication used to relieve anxiety . (medicalnewstoday.com)
- The Cornell family alleged in the lawsuit filed in 2018 in Los Angeles Superior Court that medication, especially the anti-anxiety drug lorazepam, prescribed by Dr ... According to TMZ , the lawsuit alleged that Koblin prescribed 940 doses of lorazepam in the 20 months leading up to Cornell's death. (wn.com)
- Lorazepam is a medication that is used to treat anxiety, sleeping problems that can be attributed to anxiety, and severe agitation. (lifemedspharmacy.uk)
- As a prescription-only medication, the only way to purchase Lorazepam is with a valid prescription. (lifemedspharmacy.uk)
- Lorazepam is a prescription-only medication used to treat people suffering from anxiety, sleeping disorders linked to anxiety, and severe agitation. (lifemedspharmacy.uk)
- It is also possible to become reliant on Lorazepam, to make sure this does not happen you should only take the medication as advised by your prescriber. (lifemedspharmacy.uk)
- A few people have encountered accommodating measure of progress in the uneasiness, which is for about 30 minutes and is in the wake of taking the medication Lorazepam. (buyprescriptionz.com)
- Lorazepam, a prominent member of the benzodiazepine family, stands as a widely prescribed medication with its impressive calming and sedative effects. (ivchost3.com)
Intravenous lorazepam1
- Lorazepam by mouth is given 90 to 120 minutes before procedures, and intravenous lorazepam as late as 10 minutes before procedures. (wikipedia.org)
Benzodiazepine receptors1
- Lorazepam allosterically binds on the benzodiazepine receptors in the post-synaptic GABA-A ligand-gated chloride channel in different sites of the central nervous system (CNS). (itopmeds.com)
Injection5
- Lorazepam also comes as an oral solution and a solution given by injection. (medicalnewstoday.com)
- The lorazepam injection is stored in the fridge. (medbroadcast.com)
- Appropriate studies have not been performed on the relationship of age to the effects of lorazepam injection in the pediatric population. (opioidsmedshop.com)
- Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of lorazepam injection in the elderly. (opioidsmedshop.com)
- However, elderly patients are more likely to have severe drowsiness, or age-related heart, liver, or kidney problems, which may require an adjustment in the dose in patients receiving lorazepam injection. (opioidsmedshop.com)
Status epilepticus2
- Intravenous diazepam or lorazepam are first-line treatments for convulsive status epilepticus. (wikipedia.org)
- BACKGROUND: Lorazepam is a widely prescribed benzodiazepine that is used to manage anxiety, insomnia, and status epilepticus and is used for pre-anesthetic care as well as several off-label indications including aggression, alcohol withdrawal, panic disorder, chemotherapy-associated anticipatory nausea, and catatonia. (bvsalud.org)
Adverse effects1
- The risk or severity of adverse effects can be increased when Lorazepam is combined with Venlafaxine. (druginteractionchecker.com)
Alprazolam2
- Whats are the differences between diazepam, lorazepam, alprazolam and clonazepam? (healthtap.com)
- o alprazolam, o lorazepam e o triazolam, cada qual com suas devidas propriedades e posologias de eleição. (bvsalud.org)
Tablet9
- Lorazepam oral tablet is a pill that people take by mouth. (medicalnewstoday.com)
- Is lorazepam oral tablet a controlled substance? (medicalnewstoday.com)
- Lorazepam oral tablet has a boxed warning from the Food and Drug Administration (FDA) for misuse and dependence. (medicalnewstoday.com)
- See the " Lorazepam oral tablet side effects " section below to learn more. (medicalnewstoday.com)
- Lorazepam oral tablet is a generic drug. (medicalnewstoday.com)
- This is a partial list of mild side effects from lorazepam oral tablet. (medicalnewstoday.com)
- Lorazepam 2mg, A prescribe Lorazepam 2 mg tablet is categorize as a benzodiazepine, which means that it depresses the central nervous system. (trinexpharmacy.com)
- The ladies who want pregnancy or pregnant ladies ought not take this tablet or else they ought to counsel wellbeing counselor before taking Lorazepam. (buyprescriptionz.com)
- Drug1 (rxcui = 197901, name = Lorazepam 1 MG Oral Tablet, tty = SCD). (druginteractionchecker.com)
Kopen6
- lorazepam kopen bevindt zich in de benzodiazepine-geneesmiddelengemeenschap. (shortkro.com)
- Behandel angst- en epilepsiestoornissen met Lorazepam kopen. (shortkro.com)
- Lorazepam kopen wordt als geneesmiddel aangeduid als benzodiazepine. (shortkro.com)
- Lorazepam kopen is alleen op recept verkrijgbaar. (shortkro.com)
- U kunt Lorazepam kopen en Lorazepam voor krijgen verkoop online. (shortkro.com)
- Ik zal dit blijven kopen en gebruiken. (buyprescriptionz.com)
Long does lorazepam last1
- How long does lorazepam last? (addictionblog.org)
Dose9
- Lorazepam can effectively reduce agitation and induce sleep, and the duration of effects from a single dose makes it an appropriate choice for the short-term treatment of insomnia, especially in the presence of severe anxiety or night terrors. (wikipedia.org)
- Lorazepam, an anxiolytic drug, was evaluated in a 2-mg dose using a 16-night protocol including 7 nights of drug trial. (karger.com)
- The recommended starting dose of lorazepam for adults is 2 mg per day, given in divided doses. (medbroadcast.com)
- The primary objective was to evaluate the relationship between high-dose lorazepam and serum propylene glycol concentrations. (nih.gov)
- Cumulative lorazepam dose (mg/kg) and the rate of infusion (mg.kg(-1).hr(-1)) were monitored from initiation of lorazepam infusion until 24 hrs after discontinuation of the high-dose lorazepam infusion. (nih.gov)
- Serum osmolarity was collected at 48 hrs into the high-dose lorazepam infusion and daily thereafter. (nih.gov)
- The mean cumulative high-dose lorazepam received and mean high-dose lorazepam infusion rate were 8.1 mg/kg (range, 5.1-11.7) and 0.16 mg.kg(-1).hr (-1)(range, 0.11-0.22), respectively. (nih.gov)
- A significant correlation between high-dose lorazepam infusion rate and serum propylene glycol concentrations was observed (r =.557, p =.021). (nih.gov)
- Study findings suggest that in critically ill adults with normal renal function, serum propylene glycol concentrations may be predicted by the high-dose lorazepam infusion rate and osmol gap. (nih.gov)
Doctor or pharmacist1
- To learn about other mild side effects, talk with your doctor or pharmacist, or view lorazepam oral tablet's prescribing information . (medicalnewstoday.com)
Agitation1
- Its relative effectiveness in preventing new memory formation, along with its ability to reduce agitation and anxiety, makes lorazepam useful as premedication. (wikipedia.org)
Dizziness1
- The effect of lorazepam seems to be very compartmental which was observed with a different generation of sleepiness and a dizziness effect. (itopmeds.com)
Anticonvulsant1
- The anticonvulsant properties of lorazepam are thought to be related to the binding to voltage-dependent sodium channels in which the sustained repetitive firing gets limited by the slow recovery of sodium channels due to the benzodiazepine effect. (itopmeds.com)
Nausea1
- Some off-label indications of lorazepam include rapid tranquilization of an agitated patient, alcohol withdrawal delirium, alcohol withdrawal syndrome, muscle spasms, insomnia, panic disorder, delirium, chemotherapy-associated anticipatory nausea and vomiting, and psychogenic catatonia. (itopmeds.com)
Doses2
- Single doses of lorazepam usually last for 6-8 hours. (addictionblog.org)
- And NO. Lorazepam can get you high when you take higher doses than prescribed. (addictionblog.org)
Amnesia2
- In intensive care units lorazepam is sometimes used to produce anxiolysis, hypnosis, and amnesia. (wikipedia.org)
- Collaborating with anesthesia, Lorazepam plays its part in bountiful amnesia and mitigating pre-surgical anxiety. (ivchost3.com)
Alcohol4
- Alcohol can increase both the sedative and the intoxifying effects of Lorazepam. (naturalnews.com)
- Mixing lorazepam and alcohol can cause memory loss, loss of inhibition and irritability. (addictionblog.org)
- A cream for alcohol withdrawal symptoms, Lorazepam steps in to alleviate distress and avert complications. (ivchost3.com)
- Resist the allure of alcohol and other central nervous system depressants while entwined with Lorazepam, lest drowsiness and respiratory depression enchant. (ivchost3.com)
Switch to lorazepam2
- I know that both trazodone and domperidone can prolong QT intervals so best not taken together but mother says she can switch to lorazepam instead of trazodone. (infantrisk.com)
- Mother could switch to Lorazepam instead of trazadone. (infantrisk.com)
Side effects3
- I think most people who take lorazepam are familiar with side effects like any other script, however we also know what w. (medschat.com)
- What are the side effects of Lorazepam? (lifemedspharmacy.uk)
- Lorazepam Side Effects are usually mild and wash out within a few days, and in case any side effects worsen, seek immediate medical attention. (msnho.com)
Effects2
- Tobacco may reduce the calming effects of Lorazepam and should be avoided. (naturalnews.com)
- [7] As this site is the most prolific inhibitory receptor set within the brain, its modulation results in the sedating (or calming effects ) of lorazepam on the nervous system. (psychonautwiki.org)
Orally1
- Is snorting lorazepam effective vs taking lorazepam orally? (addictionblog.org)
Wean1
- Has anybody successfully managed to successfully wean off of Lorazepam? (mayoclinic.org)
Anxiolytic1
- Lorazepam is a short-acting and rapidly cleared benzodiazepine used commonly as a sedative and anxiolytic. (itopmeds.com)
Depression1
- The emotional tide surges with Lorazepam, inviting mood swings, including bouts of depression or euphoria, to make their appearance. (ivchost3.com)
Weakness1
- Venture into the realm of rare phenomena, where Lorazepam may summon forth muscle weakness and fatigue, tugging at daily activities. (ivchost3.com)
Midazolam1
- PROCEDURES: This article examines the significant pharmacologic differences between lorazepam and midazolam. (bvsalud.org)
Dependence2
- Due to tolerance and dependence, lorazepam is recommended for short-term use, up to two to four weeks only. (wn.com)
- Enter the realm of caution with prolonged Lorazepam usage, where physical and psychological dependence may loom. (ivchost3.com)
Indications1
- Lorazepam can be utilized for transient alleviation, which is for the indications of a great deal of tension. (buyprescriptionz.com)
Toxicity1
- Risk of environmental impact of lorazepam cannot be excluded, due to the lack of environmental toxicity data. (janusinfo.se)
Content1
- The journal Evidencias en Pediatría (Evidences in Pediatrics) recognizes as inalienable the intellectual and moral rights of the authors concerning the content of their published manuscripts. (evidenciasenpediatria.es)
Drugs1
- However, phenobarbital has a superior success rate compared to lorazepam and other drugs, at least in the elderly. (wikipedia.org)
Symptoms4
- Withdrawal symptoms, including rebound insomnia and rebound anxiety, may occur after seven days' use of lorazepam. (wikipedia.org)
- Lorazepam is a benzodiazepine that works in the brain to relieve symptoms of anxiety. (opioidsmedshop.com)
- Lorazepam reduces the symptoms of excessive anxiety and worry that may arise in stressful conditions such as an exam or job interview. (rxdirectmeds.com)
- Lorazepam was initiated but did not control the catatonic symptoms. (bvsalud.org)
Effectively1
- In the monarchy of anticonvulsants, Lorazepam triumphs, effectively managing and preventing captures, particularly during emergencies. (ivchost3.com)
Overdose2
- Consider the possibility that ONE overdose OR MISSES TAKING LORAZEPAM. (buyprescriptionz.com)
- Lorazepam can probably get mishandled and it is therefore that there is much possibility of overdose. (buyprescriptionz.com)
Metabolism1
- In this setting, impaired liver function is not a hazard with lorazepam, since lorazepam does not require oxidation, in the liver or otherwise, for its metabolism. (wikipedia.org)
Additionally1
- Additionally, Lorazepam contains a hydroxy (OH-) group substituted at R 3 . (psychonautwiki.org)
Insomnia1
- Well-known for efficiently managing anxiety, insomnia, and many medical conditions, this article lean-tos light on the multi-layered aspects of Lorazepam. (ivchost3.com)
Cognitive1
- Delving deeper, cognitive impairment surfaces as a consequence of Lorazepam, especially with escalated dosages or prolonged use. (ivchost3.com)