Collections of facts, assumptions, beliefs, and heuristics that are used in combination with databases to achieve desired results, such as a diagnosis, an interpretation, or a solution to a problem (From McGraw Hill Dictionary of Scientific and Technical Terms, 6th ed).
Computer programs based on knowledge developed from consultation with experts on a problem, and the processing and/or formalizing of this knowledge using these programs in such a manner that the problems may be solved.
Theory and development of COMPUTER SYSTEMS which perform tasks that normally require human intelligence. Such tasks may include speech recognition, LEARNING; VISUAL PERCEPTION; MATHEMATICAL COMPUTING; reasoning, PROBLEM SOLVING, DECISION-MAKING, and translation of language.
Adjunctive computer programs in providing drug treatment to patients.
A system of record keeping in which a list of the patient's problems is made and all history, physical findings, laboratory data, etc. pertinent to each problem are placed under that heading.
A specified list of terms with a fixed and unalterable meaning, and from which a selection is made when CATALOGING; ABSTRACTING AND INDEXING; or searching BOOKS; JOURNALS AS TOPIC; and other documents. The control is intended to avoid the scattering of related subjects under different headings (SUBJECT HEADINGS). The list may be altered or extended only by the publisher or issuing agency. (From Harrod's Librarians' Glossary, 7th ed, p163)
A branch of biology dealing with the structure of organisms.
The body of truths or facts accumulated in the course of time, the cumulated sum of information, its volume and nature, in any civilization, period, or country.
Organized activities related to the storage, location, search, and retrieval of information.
Computer-based information systems used to integrate clinical and patient information and provide support for decision-making in patient care.
Software designed to store, manipulate, manage, and control data for specific uses.
A research and development program initiated by the NATIONAL LIBRARY OF MEDICINE to build knowledge sources for the purpose of aiding the development of systems that help health professionals retrieve and integrate biomedical information. The knowledge sources can be used to link disparate information systems to overcome retrieval problems caused by differences in terminology and the scattering of relevant information across many databases. The three knowledge sources are the Metathesaurus, the Semantic Network, and the Specialist Lexicon.
The procedures involved in combining separately developed modules, components, or subsystems so that they work together as a complete system. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The portion of an interactive computer program that issues messages to and receives commands from a user.
Books used in the study of a subject that contain a systematic presentation of the principles and vocabulary of a subject.
Social media model for enabling public involvement and recruitment in participation. Use of social media to collect feedback and recruit volunteer subjects.
Knowledge, attitudes, and associated behaviors which pertain to health-related topics such as PATHOLOGIC PROCESSES or diseases, their prevention, and treatment. This term refers to non-health workers and health workers (HEALTH PERSONNEL).
Pairing of purine and pyrimidine bases by HYDROGEN BONDING in double-stranded DNA or RNA.
A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.
Use of an interactive computer system designed to assist the physician or other health professional in choosing between certain relationships or variables for the purpose of making a diagnostic or therapeutic decision.
Extensive collections, reputedly complete, of facts and data garnered from material of a specialized subject area and made available for analysis and application. The collection can be automated by various contemporary methods for retrieval. The concept should be differentiated from DATABASES, BIBLIOGRAPHIC which is restricted to collections of bibliographic references.
Sequential operating programs and data which instruct the functioning of a digital computer.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
Specific languages used to prepare computer programs.
The relationships between symbols and their meanings.
The terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area.
Computerized compilations of information units (text, sound, graphics, and/or video) interconnected by logical nonlinear linkages that enable users to follow optimal paths through the material and also the systems used to create and display this information. (From Thesaurus of ERIC Descriptors, 1994)
Use of sophisticated analysis tools to sort through, organize, examine, and combine large sets of information.
The deliberate and methodical practice of finding new applications for existing drugs.
Computer processing of a language with rules that reflect and describe current usage rather than prescribed usage.
Application of computer programs designed to assist the physician in solving a diagnostic problem.
Books in the field of medicine intended primarily for consultation.
Integrated set of files, procedures, and equipment for the storage, manipulation, and retrieval of information.
The premier bibliographic database of the NATIONAL LIBRARY OF MEDICINE. MEDLINE® (MEDLARS Online) is the primary subset of PUBMED and can be searched on NLM's Web site in PubMed or the NLM Gateway. MEDLINE references are indexed with MEDICAL SUBJECT HEADINGS (MeSH).
An American National Standards Institute-accredited organization working on specifications to support development and advancement of clinical and administrative standards for healthcare.
Computer-based systems for input, storage, display, retrieval, and printing of information contained in a patient's medical record.
Organized collections of computer records, standardized in format and content, that are stored in any of a variety of computer-readable modes. They are the basic sets of data from which computer-readable files are created. (from ALA Glossary of Library and Information Science, 1983)
A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.
Terms or expressions which provide the major means of access by subject to the bibliographic unit.
A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.
Small computers using LSI (large-scale integration) microprocessor chips as the CPU (central processing unit) and semiconductor memories for compact, inexpensive storage of program instructions and data. They are smaller and less expensive than minicomputers and are usually built into a dedicated system where they are optimized for a particular application. "Microprocessor" may refer to just the CPU or the entire microcomputer.
A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.
Databases containing information about PROTEINS such as AMINO ACID SEQUENCE; PROTEIN CONFORMATION; and other properties.
Activities performed to identify concepts and aspects of published information and research reports.
Media that facilitate transportability of pertinent information concerning patient's illness across varied providers and geographic locations. Some versions include direct linkages to online consumer health information that is relevant to the health conditions and treatments related to a specific patient.
Drugs intended for human or veterinary use, presented in their finished dosage form. Included here are materials used in the preparation and/or formulation of the finished dosage form.
Databases devoted to knowledge about specific genes and gene products.
A branch of genetics which deals with the genetic variability in individual responses to drugs and drug metabolism (BIOTRANSFORMATION).
Systems composed of a computer or computers, peripheral equipment, such as disks, printers, and terminals, and telecommunications capabilities.
Mathematical or statistical procedures used as aids in making a decision. They are frequently used in medical decision-making.
Specifications and instructions applied to the software.
Information systems, usually computer-assisted, that enable providers to initiate medical procedures, prescribe medications, etc. These systems support medical decision-making and error-reduction during patient care.
Integrated, computer-assisted systems designed to store, manipulate, and retrieve information concerned with the administrative and clinical aspects of providing medical services within the hospital.
Systematic organization, storage, retrieval, and dissemination of specialized information, especially of a scientific or technical nature (From ALA Glossary of Library and Information Science, 1983). It often involves authenticating or validating information.
A self-learning technique, usually online, involving interaction of the student with programmed instructional materials.
The field of information science concerned with the analysis and dissemination of medical data through the application of computers to various aspects of health care and medicine.
A definite pathologic process with a characteristic set of signs and symptoms. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown.
The process of pictorial communication, between human and computers, in which the computer input and output have the form of charts, drawings, or other appropriate pictorial representation.
A system containing any combination of computers, computer terminals, printers, audio or visual display devices, or telephones interconnected by telecommunications equipment or cables: used to transmit or receive information. (Random House Unabridged Dictionary, 2d ed)
Three-dimensional representation to show anatomic structures. Models may be used in place of intact animals or organisms for teaching, practice, and study.
The inferior region of the skull consisting of an internal (cerebral), and an external (basilar) surface.
The systematic study of the complete DNA sequences (GENOME) of organisms.
Systems where the input data enter the computer directly from the point of origin (usually a terminal or workstation) and/or in which output data are transmitted directly to that terminal point of origin. (Sippl, Computer Dictionary, 4th ed)
The capability to perform acceptably those duties directly related to patient care.
The relative amounts of the PURINES and PYRIMIDINES in a nucleic acid.
Condensation products of aromatic amines and aldehydes forming azomethines substituted on the N atom, containing the general formula R-N:CHR. (From Grant & Hackh's Chemical Dictionary, 5th ed)
Directions or principles presenting current or future rules of policy for assisting health care practitioners in patient care decisions regarding diagnosis, therapy, or related clinical circumstances. The guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by the convening of expert panels. The guidelines form a basis for the evaluation of all aspects of health care and delivery.
A medical specialty concerned with the diagnosis and treatment of diseases of the internal organ systems of adults.
A course of study offered by an educational institution.
The term "United States" in a medical context often refers to the country where a patient or study participant resides, and is not a medical term per se, but relevant for epidemiological studies, healthcare policies, and understanding differences in disease prevalence, treatment patterns, and health outcomes across various geographic locations.
Complex sets of enzymatic reactions connected to each other via their product and substrate metabolites.
The assessing of academic or educational achievement. It includes all aspects of testing and test construction.
In INFORMATION RETRIEVAL, machine-sensing or identification of visible patterns (shapes, forms, and configurations). (Harrod's Librarians' Glossary, 7th ed)
Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.
Introduction of changes which are new to the organization and are created by management.
The teaching or training of patients concerning their own health needs.
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
Studies determining the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies. For drugs and devices, CLINICAL TRIALS AS TOPIC; DRUG EVALUATION; and DRUG EVALUATION, PRECLINICAL are available.
Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)
Comprehensive, methodical analysis of complex biological systems by monitoring responses to perturbations of biological processes. Large scale, computerized collection and analysis of the data are used to develop and test models of biological systems.
Interacting DNA-encoded regulatory subsystems in the GENOME that coordinate input from activator and repressor TRANSCRIPTION FACTORS during development, cell differentiation, or in response to environmental cues. The networks function to ultimately specify expression of particular sets of GENES for specific conditions, times, or locations.
Systematic gathering of data for a particular purpose from various sources, including questionnaires, interviews, observation, existing records, and electronic devices. The process is usually preliminary to statistical analysis of the data.
The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.
Computer-based representation of physical systems and phenomena such as chemical processes.
A plan for collecting and utilizing data so that desired information can be obtained with sufficient precision or so that an hypothesis can be tested properly.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The complete genetic complement contained in the DNA of a set of CHROMOSOMES in a HUMAN. The length of the human genome is about 3 billion base pairs.
The protein complement of an organism coded for by its genome.
The systematic study of the complete complement of proteins (PROTEOME) of organisms.
The leveraging of collective wisdom within an organization as a catalyst to increase responsiveness and innovation.
Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.
Theoretical representations that simulate the behavior or activity of systems, processes, or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.
The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.
Studies designed to assess the efficacy of programs. They may include the evaluation of cost-effectiveness, the extent to which objectives are met, or impact.

PROTEOME-3D: an interactive bioinformatics tool for large-scale data exploration and knowledge discovery. (1/335)

Comprehensive understanding of biological systems requires efficient and systematic assimilation of high-throughput datasets in the context of the existing knowledge base. A major limitation in the field of proteomics is the lack of an appropriate software platform that can synthesize a large number of experimental datasets in the context of the existing knowledge base. Here, we describe a software platform, termed PROTEOME-3D, that utilizes three essential features for systematic analysis of proteomics data: creation of a scalable, queryable, customized database for identified proteins from published literature; graphical tools for displaying proteome landscapes and trends from multiple large-scale experiments; and interactive data analysis that facilitates identification of crucial networks and pathways. Thus, PROTEOME-3D offers a standardized platform to analyze high-throughput experimental datasets for the identification of crucial players in co-regulated pathways and cellular processes.  (+info)

Generic, simple risk stratification model for heart valve surgery. (2/335)

BACKGROUND: Heart valve surgery has an associated in-hospital mortality rate of 4% to 8%. This study aims to develop a simple risk model to predict the risk of in-hospital mortality for patients undergoing heart valve surgery to provide information to patients and clinicians and to facilitate institutional comparisons. METHODS AND RESULTS: Data on 32,839 patients were obtained from the Society of Cardiothoracic Surgeons of Great Britain and Ireland on patients who underwent heart valve surgery between April 1995 and March 2003. Data from the first 5 years (n=16,679) were used to develop the model; its performance was evaluated on the remaining data (n=16,160). The risk model presented here is based on the combined data. The overall in-hospital mortality was 6.4%. The risk model included, in order of importance (all P<0.01), operative priority, age, renal failure, operation sequence, ejection fraction, concomitant tricuspid valve surgery, type of valve operation, concomitant CABG surgery, body mass index, preoperative arrhythmias, diabetes, gender, and hypertension. The risk model exhibited good predictive ability (Hosmer-Lemeshow test, P=0.78) and discriminated between high- and low-risk patients reasonably well (receiver-operating characteristics curve area, 0.77). CONCLUSIONS: This is the first risk model that predicts in-hospital mortality for aortic and/or mitral heart valve patients with or without concomitant CABG. Based on a large national database of heart valve patients, this model has been evaluated successfully on patients who had valve surgery during a subsequent time period. It is simple to use, includes routinely collected variables, and provides a useful tool for patient advice and institutional comparisons.  (+info)

An audit of lamotrigine, levetiracetam and topiramate usage for epilepsy in a district general hospital. (3/335)

The aim of this audit was to ascertain outcomes for people who had taken or who were still taking three "new generation" broad-spectrum antiepileptic drugs (AEDs), namely lamotrigine, levetiracetam and topiramate. Thirteen percent of people became seizure free and approximately, one-third had a reduction of greater than 50% in their seizures. Two-thirds of people were still taking their audit AED. In addition, approximately one-third of people with a learning disability derived substantial benefit, although the rate of seizure freedom was lower. All three AEDs were most successful at treating primary generalised epilepsy and least successful with symptomatic generalised epilepsy. With some reservations the data suggests that levetiracetam and topiramate are the most efficacious AEDs, but topiramate is the least well tolerated. These results mean consideration of a "general prescribing policy" is important when using and choosing these AEDs. We conclude that lamotrigine, levetiracetam and topiramate are useful additions to the armamentarium of AEDs.  (+info)

Incorporating biological knowledge into distance-based clustering analysis of microarray gene expression data. (4/335)

MOTIVATION: Because co-expressed genes are likely to share the same biological function, cluster analysis of gene expression profiles has been applied for gene function discovery. Most existing clustering methods ignore known gene functions in the process of clustering. RESULTS: To take advantage of accumulating gene functional annotations, we propose incorporating known gene functions into a new distance metric, which shrinks a gene expression-based distance towards 0 if and only if the two genes share a common gene function. A two-step procedure is used. First, the shrinkage distance metric is used in any distance-based clustering method, e.g. K-medoids or hierarchical clustering, to cluster the genes with known functions. Second, while keeping the clustering results from the first step for the genes with known functions, the expression-based distance metric is used to cluster the remaining genes of unknown function, assigning each of them to either one of the clusters obtained in the first step or some new clusters. A simulation study and an application to gene function prediction for the yeast demonstrate the advantage of our proposal over the standard method.  (+info)

A case study in pathway knowledgebase verification. (5/335)

BACKGROUND: Biological databases and pathway knowledge-bases are proliferating rapidly. We are developing software tools for computer-aided hypothesis design and evaluation, and we would like our tools to take advantage of the information stored in these repositories. But before we can reliably use a pathway knowledge-base as a data source, we need to proofread it to ensure that it can fully support computer-aided information integration and inference. RESULTS: We design a series of logical tests to detect potential problems we might encounter using a particular knowledge-base, the Reactome database, with a particular computer-aided hypothesis evaluation tool, HyBrow. We develop an explicit formal language from the language implicit in the Reactome data format and specify a logic to evaluate models expressed using this language. We use the formalism of finite model theory in this work. We then use this logic to formulate tests for desirable properties (such as completeness, consistency, and well-formedness) for pathways stored in Reactome. We apply these tests to the publicly available Reactome releases (releases 10 through 14) and compare the results, which highlight Reactome's steady improvement in terms of decreasing inconsistencies. We also investigate and discuss Reactome's potential for supporting computer-aided inference tools. CONCLUSION: The case study described in this work demonstrates that it is possible to use our model theory based approach to identify problems one might encounter using a knowledge-base to support hypothesis evaluation tools. The methodology we use is general and is in no way restricted to the specific knowledge-base employed in this case study. Future application of this methodology will enable us to compare pathway resources with respect to the generic properties such resources will need to possess if they are to support automated reasoning.  (+info)

First multi-centre evaluation of a knowledge-based implant-assistant for implantable cardioverter-defibrillators. (6/335)

AIMS: Modern implantable cardioverter-defibrillators (ICDs) place increasing demands on the physician, as their complexity requires more and more knowledge and effort in handling them. To overcome this problem an implant-assistant has been developed, which transfers clinical data entered by the physician into a complete set of parameters for programming a dual-chamber ICD (Tachos-DR, Biotronik, Berlin, Germany) at DFT testing (DFT-Prog) and first permanent programming (Perm-Prog) after implant. METHODS AND RESULTS: Routine ICD implantations were initially evaluated by clinical experts at 19 centres in USA and Europe from 178 patient files. The rating of parameters was related to the number of parameters available in each patient. For DFT-Prog, 98.4% of parameter suggestions were identical to experts' expectations, an additional 1.0% were accepted, 0.5% were rejected, and none was considered harmful. This resulted in an overall acceptance of 94.4% of the DFT-Prog. For Perm-Prog, 96.1% of parameters were identical to those advised by experts, an additional 2.4% were accepted, 1.5% rejected, and seven parameters (0.04%) were considered potentially harmful by experts with an overall acceptance of 86.5%. Adaptation of the implant-assistant increased the overall acceptance to 100% for DFT-Prog and 90.6% for first Perm-Prog without any potentially harmful suggestions. CONCLUSION: The ICD implant-assistant, which allows the physician to programme ICDs directly from clinical data, is a promising method to simplify the programming of modern ICDs.  (+info)

Qualitative pharmacokinetic modeling of drugs. (7/335)

We hypothesize that a representation of drug-drug interactions (DDIs) based on physiologic, pharmacokinetic (PK) and pharmacodynamic (PD) mechanisms will provide more accurate and useful information to clinicians than current approaches that simply tabulate and index pairwise interactions of drugs. This paper explores the strengths, weaknesses, and difficulties of modeling drug mechanisms and reports on our initial work designing and implementing a drug KB based on qualitative pharmacokinetic mechanisms.  (+info)

Mining a clinical data warehouse to discover disease-finding associations using co-occurrence statistics. (8/335)

This paper applies co-occurrence statistics to discover disease-finding associations in a clinical data warehouse. We used two methods, chi2 statistics and the proportion confidence interval (PCI) method, to measure the dependence of pairs of diseases and findings, and then used heuristic cutoff values for association selection. An intrinsic evaluation showed that 94 percent of disease-finding associations obtained by chi2 statistics and 76.8 percent obtained by the PCI method were true associations. The selected associations were used to construct knowledge bases of disease-finding relations (KB-chi2, KB-PCI). An extrinsic evaluation showed that both KB-chi2 and KB-PCI could assist in eliminating clinically non-informative and redundant findings from problem lists generated by our automated problem list summarization system.  (+info)

I'm sorry for any confusion, but "knowledge bases" is a general term that refers to structured collections of knowledge in a specific field or area, and it is not a medical term with a defined meaning in the medical field. Knowledge bases can be found in many fields, including medicine, and they typically take the form of databases or repositories of information that are used to store, organize, and retrieve knowledge. In the medical field, knowledge bases might include information about diseases, treatments, medications, and other medical topics. They can be used by healthcare professionals, researchers, and patients to access accurate and reliable information.

An Expert System is a type of artificial intelligence (AI) program that emulates the decision-making ability of a human expert in a specific field or domain. It is designed to solve complex problems by using a set of rules, heuristics, and knowledge base derived from human expertise. The system can simulate the problem-solving process of a human expert, allowing it to provide advice, make recommendations, or diagnose problems in a similar manner. Expert systems are often used in fields such as medicine, engineering, finance, and law where specialized knowledge and experience are critical for making informed decisions.

The medical definition of 'Expert Systems' refers to AI programs that assist healthcare professionals in diagnosing and treating medical conditions, based on a large database of medical knowledge and clinical expertise. These systems can help doctors and other healthcare providers make more accurate diagnoses, recommend appropriate treatments, and provide patient education. They may also be used for research, training, and quality improvement purposes.

Expert systems in medicine typically use a combination of artificial intelligence techniques such as rule-based reasoning, machine learning, natural language processing, and pattern recognition to analyze medical data and provide expert advice. Examples of medical expert systems include MYCIN, which was developed to diagnose infectious diseases, and Internist-1, which assists in the diagnosis and management of internal medicine cases.

Artificial Intelligence (AI) in the medical context refers to the simulation of human intelligence processes by machines, particularly computer systems. These processes include learning (the acquisition of information and rules for using the information), reasoning (using the rules to reach approximate or definite conclusions), and self-correction.

In healthcare, AI is increasingly being used to analyze large amounts of data, identify patterns, make decisions, and perform tasks that would normally require human intelligence. This can include tasks such as diagnosing diseases, recommending treatments, personalizing patient care, and improving clinical workflows.

Examples of AI in medicine include machine learning algorithms that analyze medical images to detect signs of disease, natural language processing tools that extract relevant information from electronic health records, and robot-assisted surgery systems that enable more precise and minimally invasive procedures.

Computer-assisted drug therapy refers to the use of computer systems and technology to support and enhance medication management and administration. This can include a variety of applications such as:

1. Medication ordering and prescribing systems that help reduce errors by providing alerts for potential drug interactions, dosage issues, and allergies.
2. Computerized physician order entry (CPOE) systems that allow healthcare providers to enter, review, and modify medication orders electronically.
3. Electronic medication administration records (eMARs) that track the administration of medications to patients in real-time, reducing errors and improving patient safety.
4. Clinical decision support systems (CDSS) that provide evidence-based recommendations for medication therapy based on patient-specific data.
5. Medication reconciliation systems that help ensure accurate and up-to-date medication lists for patients during transitions of care.

Overall, computer-assisted drug therapy aims to improve the safety, efficacy, and efficiency of medication management by reducing errors, enhancing communication, and providing timely access to relevant patient information.

Problem-Oriented Medical Records (PMR) is a system for organizing and documenting patient information in a structured and standardized format. It was introduced in the 1960s by Dr. Lawrence Weed as a way to improve the quality and efficiency of medical care.

The core component of PMR is the problem list, which is a comprehensive and prioritized list of the patient's current and past medical problems. Each problem is assigned a unique identifier, and all subsequent documentation related to that problem is linked to it. This allows for easy access to relevant information and facilitates continuity of care.

PMR also includes other sections such as the database, which contains information about the patient's history, physical examination findings, laboratory results, and other diagnostic tests; the progress notes, which document the assessment and management of the patient's problems over time; and the discharge summary, which summarizes the patient's hospital course and provides recommendations for follow-up care.

PMR is designed to promote clear communication, evidence-based decision making, and effective coordination of care among healthcare providers. It has been widely adopted in various settings, including hospitals, clinics, and electronic health records (EHR) systems.

A controlled vocabulary in a medical context refers to a specific set of standardized terms and phrases that are used in clinical documentation and communication. These vocabularies are often created and maintained by professional organizations or governmental bodies to ensure consistency, accuracy, and interoperability in the sharing and retrieval of health information.

Controlled vocabularies can include terminologies such as Systematized Nomenclature of Medicine (SNOMED), International Classification of Diseases (ICD), Logical Observation Identifiers Names and Codes (LOINC), and RxNorm, among others. By using a controlled vocabulary, healthcare providers can more easily share and analyze health data, support clinical decision-making, and facilitate accurate coding and billing.

Anatomy is the branch of biology that deals with the study of the structure of organisms and their parts. In medicine, anatomy is the detailed study of the structures of the human body and its organs. It can be divided into several subfields, including:

1. Gross anatomy: Also known as macroscopic anatomy, this is the study of the larger structures of the body, such as the organs and organ systems, using techniques such as dissection and observation.
2. Histology: This is the study of tissues at the microscopic level, including their structure, composition, and function.
3. Embryology: This is the study of the development of the embryo and fetus from conception to birth.
4. Neuroanatomy: This is the study of the structure and organization of the nervous system, including the brain and spinal cord.
5. Comparative anatomy: This is the study of the structures of different species and how they have evolved over time.

Anatomy is a fundamental subject in medical education, as it provides the basis for understanding the function of the human body and the underlying causes of disease.

In the context of medicine, 'knowledge' refers to the understanding and comprehension of medical facts, principles, theories, and practices that are acquired through education, training, research, and experience. This encompasses a deep familiarity with anatomy, physiology, pathophysiology, pharmacology, clinical guidelines, and evidence-based practices. It also includes awareness of current research developments, emerging trends, and best practices in the field. Medical knowledge is constantly evolving and requires healthcare professionals to engage in lifelong learning to maintain their expertise and provide high-quality care to patients.

'Information Storage and Retrieval' in the context of medical informatics refers to the processes and systems used for the recording, storing, organizing, protecting, and retrieving electronic health information (e.g., patient records, clinical data, medical images) for various purposes such as diagnosis, treatment planning, research, and education. This may involve the use of electronic health record (EHR) systems, databases, data warehouses, and other digital technologies that enable healthcare providers to access and share accurate, up-to-date, and relevant information about a patient's health status, medical history, and care plan. The goal is to improve the quality, safety, efficiency, and coordination of healthcare delivery by providing timely and evidence-based information to support clinical decision-making and patient engagement.

Decision Support Systems (DSS), Clinical are interactive computer-based information systems that help health care professionals and patients make informed clinical decisions. These systems use patient-specific data and clinical knowledge to generate patient-centered recommendations. They are designed to augment the decision-making abilities of clinicians, providing evidence-based suggestions while allowing for the integration of professional expertise, patient preferences, and values. Clinical DSS can support various aspects of healthcare delivery, including diagnosis, treatment planning, resource allocation, and quality improvement. They may incorporate a range of technologies, such as artificial intelligence, machine learning, and data analytics, to facilitate the processing and interpretation of complex clinical information.

A Database Management System (DBMS) is a software application that enables users to define, create, maintain, and manipulate databases. It provides a structured way to organize, store, retrieve, and manage data in a digital format. The DBMS serves as an interface between the database and the applications or users that access it, allowing for standardized interactions and data access methods. Common functions of a DBMS include data definition, data manipulation, data security, data recovery, and concurrent data access control. Examples of DBMS include MySQL, Oracle, Microsoft SQL Server, and MongoDB.

The Unified Medical Language System (UMLS) is a set of files and software developed by the U.S. National Library of Medicine (NLM). It provides a comprehensive source of biomedical and health-related terms aimed at unifying and standardizing the language used in various areas of the medical field, such as clinical care, research, and education.

The UMLS includes many different vocabularies, classifications, and coding systems, including but not limited to:

* Systematized Nomenclature of Medicine--Clinical Terms (SNOMED CT)
* International Classification of Diseases (ICD)
* Current Procedural Terminology (CPT)
* Logical Observation Identifiers Names and Codes (LOINC)

By integrating these various terminologies, the UMLS enables more effective searching, information retrieval, and data analysis across different systems and databases. It also supports natural language processing (NLP) applications, such as text mining and clinical decision support systems.

I'm sorry for any confusion, but "Systems Integration" is not a medical term per se. It is a term more commonly used in the fields of engineering, computer science, and information technology. However, I can provide you with a general definition:

Systems Integration refers to the process of combining different sub-systems or components into a single, cohesive system to allow seamless communication and data exchange between them. This integration aims to improve efficiency, performance, and overall functionality by unifying various standalone systems into an interconnected network that behaves as a unified whole.

In the context of healthcare, systems integration can be applied to merge different electronic health record (EHR) systems, medical devices, or other healthcare technologies to create a comprehensive, interoperable healthcare information system. This facilitates better care coordination, data sharing, and decision-making among healthcare providers, ultimately enhancing patient outcomes and satisfaction.

A User-Computer Interface (also known as Human-Computer Interaction) refers to the point at which a person (user) interacts with a computer system. This can include both hardware and software components, such as keyboards, mice, touchscreens, and graphical user interfaces (GUIs). The design of the user-computer interface is crucial in determining the usability and accessibility of a computer system for the user. A well-designed interface should be intuitive, efficient, and easy to use, minimizing the cognitive load on the user and allowing them to effectively accomplish their tasks.

"Textbooks as Topic" is a medical subject heading (MeSH) used in the National Library of Medicine's cataloging system to describe works that are about textbooks as a genre or medium, rather than a specific subject. This can include discussions on the history of medical textbooks, their role in medical education, comparisons between different types of textbooks, and analysis of their content and effectiveness. It may also cover issues related to the production, distribution, and accessibility of medical textbooks.

Crowdsourcing is not a medical term, but rather a general term used to describe the process of obtaining ideas, services, or content by soliciting contributions from a large number of people, typically via the internet. In a medical context, crowdsourcing may be used in research, clinical trials, or patient care to gather data, opinions, or solutions from a diverse group of individuals. For example, researchers may use crowdsourcing to gather data on the symptoms and experiences of patients with a particular condition, or clinicians may use it to get input on challenging diagnostic cases.

"Health Knowledge, Attitudes, and Practices" (HKAP) is a term used in public health to refer to the knowledge, beliefs, assumptions, and behaviors that individuals possess or engage in that are related to health. Here's a brief definition of each component:

1. Health Knowledge: Refers to the factual information and understanding that individuals have about various health-related topics, such as anatomy, physiology, disease processes, and healthy behaviors.
2. Attitudes: Represent the positive or negative evaluations, feelings, or dispositions that people hold towards certain health issues, practices, or services. These attitudes can influence their willingness to adopt and maintain healthy behaviors.
3. Practices: Encompass the specific actions or habits that individuals engage in related to their health, such as dietary choices, exercise routines, hygiene practices, and use of healthcare services.

HKAP is a multidimensional concept that helps public health professionals understand and address various factors influencing individual and community health outcomes. By assessing and addressing knowledge gaps, negative attitudes, or unhealthy practices, interventions can be designed to promote positive behavior change and improve overall health status.

Base pairing is a specific type of chemical bonding that occurs between complementary base pairs in the nucleic acid molecules DNA and RNA. In DNA, these bases are adenine (A), thymine (T), guanine (G), and cytosine (C). Adenine always pairs with thymine via two hydrogen bonds, while guanine always pairs with cytosine via three hydrogen bonds. This precise base pairing is crucial for the stability of the double helix structure of DNA and for the accurate replication and transcription of genetic information. In RNA, uracil (U) takes the place of thymine and pairs with adenine.

I'm sorry for any confusion, but "Internet" is a term that pertains to the global network of interconnected computers and servers that enable the transmission and reception of data via the internet protocol (IP). It is not a medical term and does not have a specific medical definition. If you have any questions related to medicine or health, I'd be happy to try to help answer them for you!

Computer-assisted decision making in a medical context refers to the use of computer systems and software to support and enhance the clinical decision-making process. These systems can analyze patient data, such as medical history, laboratory results, and imaging studies, and provide healthcare providers with evidence-based recommendations for diagnosis and treatment.

Computer-assisted decision making tools may include:

1. Clinical Decision Support Systems (CDSS): CDSS are interactive software programs that analyze patient data and provide healthcare providers with real-time clinical guidance based on established best practices and guidelines.
2. Artificial Intelligence (AI) and Machine Learning (ML) algorithms: AI and ML can be used to analyze large datasets of medical information, identify patterns and trends, and make predictions about individual patients' health outcomes.
3. Telemedicine platforms: Telemedicine platforms enable remote consultations between healthcare providers and patients, allowing for real-time decision making based on shared data and clinical expertise.
4. Electronic Health Records (EHRs): EHRs provide a centralized repository of patient information that can be accessed and analyzed by healthcare providers to inform clinical decision making.

Overall, computer-assisted decision making has the potential to improve the quality and safety of medical care by providing healthcare providers with timely and accurate information to support their clinical judgments. However, it is important to note that these tools should always be used in conjunction with clinical expertise and human judgment, as they are not a substitute for the knowledge and experience of trained healthcare professionals.

A factual database in the medical context is a collection of organized and structured data that contains verified and accurate information related to medicine, healthcare, or health sciences. These databases serve as reliable resources for various stakeholders, including healthcare professionals, researchers, students, and patients, to access evidence-based information for making informed decisions and enhancing knowledge.

Examples of factual medical databases include:

1. PubMed: A comprehensive database of biomedical literature maintained by the US National Library of Medicine (NLM). It contains citations and abstracts from life sciences journals, books, and conference proceedings.
2. MEDLINE: A subset of PubMed, MEDLINE focuses on high-quality, peer-reviewed articles related to biomedicine and health. It is the primary component of the NLM's database and serves as a critical resource for healthcare professionals and researchers worldwide.
3. Cochrane Library: A collection of systematic reviews and meta-analyses focused on evidence-based medicine. The library aims to provide unbiased, high-quality information to support clinical decision-making and improve patient outcomes.
4. OVID: A platform that offers access to various medical and healthcare databases, including MEDLINE, Embase, and PsycINFO. It facilitates the search and retrieval of relevant literature for researchers, clinicians, and students.
5. ClinicalTrials.gov: A registry and results database of publicly and privately supported clinical studies conducted around the world. The platform aims to increase transparency and accessibility of clinical trial data for healthcare professionals, researchers, and patients.
6. UpToDate: An evidence-based, physician-authored clinical decision support resource that provides information on diagnosis, treatment, and prevention of medical conditions. It serves as a point-of-care tool for healthcare professionals to make informed decisions and improve patient care.
7. TRIP Database: A search engine designed to facilitate evidence-based medicine by providing quick access to high-quality resources, including systematic reviews, clinical guidelines, and practice recommendations.
8. National Guideline Clearinghouse (NGC): A database of evidence-based clinical practice guidelines and related documents developed through a rigorous review process. The NGC aims to provide clinicians, healthcare providers, and policymakers with reliable guidance for patient care.
9. DrugBank: A comprehensive, freely accessible online database containing detailed information about drugs, their mechanisms, interactions, and targets. It serves as a valuable resource for researchers, healthcare professionals, and students in the field of pharmacology and drug discovery.
10. Genetic Testing Registry (GTR): A database that provides centralized information about genetic tests, test developers, laboratories offering tests, and clinical validity and utility of genetic tests. It serves as a resource for healthcare professionals, researchers, and patients to make informed decisions regarding genetic testing.

I am not aware of a widely accepted medical definition for the term "software," as it is more commonly used in the context of computer science and technology. Software refers to programs, data, and instructions that are used by computers to perform various tasks. It does not have direct relevance to medical fields such as anatomy, physiology, or clinical practice. If you have any questions related to medicine or healthcare, I would be happy to try to help with those instead!

A base sequence in the context of molecular biology refers to the specific order of nucleotides in a DNA or RNA molecule. In DNA, these nucleotides are adenine (A), guanine (G), cytosine (C), and thymine (T). In RNA, uracil (U) takes the place of thymine. The base sequence contains genetic information that is transcribed into RNA and ultimately translated into proteins. It is the exact order of these bases that determines the genetic code and thus the function of the DNA or RNA molecule.

I'm afraid there seems to be a misunderstanding. Programming languages are a field of study in computer science and are not related to medicine. They are used to create computer programs, through the composition of symbols and words. Some popular programming languages include Python, Java, C++, and JavaScript. If you have any questions about programming or computer science, I'd be happy to try and help answer them!

I'm sorry for any confusion, but "semantics" is not a term that has a specific medical definition. Semantics is actually a branch of linguistics that deals with the study of meaning, reference, and the interpretation of signs and symbols, either individually or in combination. It is used in various fields including computer science, anthropology, psychology, and philosophy.

However, if you have any medical terms or concepts that you would like me to explain, I'd be happy to help!

"Terminology as a topic" in the context of medical education and practice refers to the study and use of specialized language and terms within the field of medicine. This includes understanding the meaning, origins, and appropriate usage of medical terminology in order to effectively communicate among healthcare professionals and with patients. It may also involve studying the evolution and cultural significance of medical terminology. The importance of "terminology as a topic" lies in promoting clear and accurate communication, which is essential for providing safe and effective patient care.

I'm sorry for any confusion, but "hypermedia" is not a term that has a specific medical definition. Hypermedia is a general term used in information technology and computing to describe a non-linear medium of information that includes graphics, audio, video, text, and hyperlinks. It allows users to navigate through the information in a flexible, non-sequential manner by clicking on hyperlinks that connect related pieces of information.

If you have any questions about medical terminology or concepts, I would be happy to help!

Data mining, in the context of health informatics and medical research, refers to the process of discovering patterns, correlations, and insights within large sets of patient or clinical data. It involves the use of advanced analytical techniques such as machine learning algorithms, statistical models, and artificial intelligence to identify and extract useful information from complex datasets.

The goal of data mining in healthcare is to support evidence-based decision making, improve patient outcomes, and optimize resource utilization. Applications of data mining in healthcare include predicting disease outbreaks, identifying high-risk patients, personalizing treatment plans, improving clinical workflows, and detecting fraud and abuse in healthcare systems.

Data mining can be performed on various types of healthcare data, including electronic health records (EHRs), medical claims databases, genomic data, imaging data, and sensor data from wearable devices. However, it is important to ensure that data mining techniques are used ethically and responsibly, with appropriate safeguards in place to protect patient privacy and confidentiality.

Drug repositioning, also known as drug repurposing or therapeutic switching, refers to the process of discovering new uses for approved or investigational drugs that are outside the scope of their original medical indication. This strategy leverages existing knowledge about a drug's safety, efficacy, and pharmacological properties to expedite development and reduce costs compared to de novo drug discovery. By finding new therapeutic applications for existing drugs, drug repositioning can provide faster and more cost-effective treatment options for various diseases, including neglected and rare disorders.

I'm sorry for any confusion, but "Natural Language Processing" (NLP) is actually a subfield of artificial intelligence that focuses on the interaction between computers and human language. It involves developing algorithms and software to understand, interpret, and generate human language in a valuable way.

In a medical context, NLP can be used to analyze electronic health records, clinical notes, and other forms of medical documentation to extract meaningful information, support clinical decision-making, and improve patient care. For example, NLP can help identify patients at risk for certain conditions, monitor treatment responses, and detect adverse drug events.

However, NLP is not a medical term or concept itself, so it doesn't have a specific medical definition.

Computer-assisted diagnosis (CAD) is the use of computer systems to aid in the diagnostic process. It involves the use of advanced algorithms and data analysis techniques to analyze medical images, laboratory results, and other patient data to help healthcare professionals make more accurate and timely diagnoses. CAD systems can help identify patterns and anomalies that may be difficult for humans to detect, and they can provide second opinions and flag potential errors or uncertainties in the diagnostic process.

CAD systems are often used in conjunction with traditional diagnostic methods, such as physical examinations and patient interviews, to provide a more comprehensive assessment of a patient's health. They are commonly used in radiology, pathology, cardiology, and other medical specialties where imaging or laboratory tests play a key role in the diagnostic process.

While CAD systems can be very helpful in the diagnostic process, they are not infallible and should always be used as a tool to support, rather than replace, the expertise of trained healthcare professionals. It's important for medical professionals to use their clinical judgment and experience when interpreting CAD results and making final diagnoses.

Medical reference books are comprehensive and authoritative resources that provide detailed information about various aspects of medical science, diagnosis, treatment, and patient care. These books serve as a crucial source of knowledge for healthcare professionals, students, researchers, and educators in the medical field. They cover a wide range of topics including anatomy, physiology, pathology, pharmacology, clinical procedures, medical ethics, and public health issues.

Some common types of medical reference books are:

1. Textbooks: These are extensive resources that offer in-depth knowledge on specific medical subjects or general medical principles. They often contain illustrations, diagrams, and case studies to facilitate learning and understanding. Examples include Gray's Anatomy for detailed human anatomy or Harrison's Principles of Internal Medicine for internal medicine.

2. Handbooks: These are compact and concise guides that focus on practical applications of medical knowledge. They are designed to be easily accessible and quickly referenced during patient care. Examples include the Merck Manual, which provides information on various diseases and their management, or the Oxford Handbook of Clinical Medicine for quick reference during clinical practice.

3. Formularies: These books contain detailed information about medications, including dosages, side effects, drug interactions, and contraindications. They help healthcare professionals make informed decisions when prescribing medications to patients. Examples include the British National Formulary (BNF) or the American Hospital Formulary Service (AHFS).

4. Atlases: These are visual resources that provide detailed illustrations or photographs of human anatomy, pathology, or medical procedures. They serve as valuable tools for learning and teaching medical concepts. Examples include Netter's Atlas of Human Anatomy or Sabiston Textbook of Surgery.

5. Dictionaries: These reference books provide definitions and explanations of medical terms, abbreviations, and jargon. They help healthcare professionals and students understand complex medical language. Examples include Dorland's Illustrated Medical Dictionary or Stedman's Medical Dictionary.

6. Directories: These resources list contact information for healthcare facilities, organizations, and professionals. They are useful for locating specific services or individuals within the medical community. Examples include the American Medical Association (AMA) Directory of Physicians or the National Provider Identifier (NPI) Registry.

7. Guidelines: These books provide evidence-based recommendations for clinical practice in various medical specialties. They help healthcare professionals make informed decisions when managing patient care. Examples include the Infectious Diseases Society of America (IDSA) guidelines or the American College of Cardiology (ACC)/American Heart Association (AHA) guidelines.

8. Research compendiums: These resources compile research articles, reviews, and meta-analyses on specific medical topics. They help healthcare professionals stay up-to-date with the latest scientific findings and advancements in their field. Examples include the Cochrane Library or the Journal of the American Medical Association (JAMA).

9. Case reports: These books present detailed accounts of individual patient cases, including symptoms, diagnoses, treatments, and outcomes. They serve as valuable learning tools for healthcare professionals and students. Examples include the Archives of Internal Medicine or the New England Journal of Medicine.

10. Ethics manuals: These resources provide guidance on ethical issues in medicine, such as informed consent, patient autonomy, and confidentiality. They help healthcare professionals navigate complex moral dilemmas in their practice. Examples include the American Medical Association (AMA) Code of Medical Ethics or the World Medical Association (WMA) Declaration of Geneva.

In the context of healthcare, an Information System (IS) is a set of components that work together to collect, process, store, and distribute health information. This can include hardware, software, data, people, and procedures that are used to create, process, and communicate information.

Healthcare IS support various functions within a healthcare organization, such as:

1. Clinical information systems: These systems support clinical workflows and decision-making by providing access to patient records, order entry, results reporting, and medication administration records.
2. Financial information systems: These systems manage financial transactions, including billing, claims processing, and revenue cycle management.
3. Administrative information systems: These systems support administrative functions, such as scheduling appointments, managing patient registration, and tracking patient flow.
4. Public health information systems: These systems collect, analyze, and disseminate public health data to support disease surveillance, outbreak investigation, and population health management.

Healthcare IS must comply with various regulations, including the Health Insurance Portability and Accountability Act (HIPAA), which governs the privacy and security of protected health information (PHI). Effective implementation and use of healthcare IS can improve patient care, reduce errors, and increase efficiency within healthcare organizations.

Medline is not a medical condition or term, but rather a biomedical bibliographic database, which is a component of the U.S. National Library of Medicine (NLM)'s PubMed system. It contains citations and abstracts from scientific literature in the fields of life sciences, biomedicine, and clinical medicine, with a focus on articles published in peer-reviewed journals. Medline covers a wide range of topics, including research articles, reviews, clinical trials, and case reports. The database is updated daily and provides access to over 26 million references from the years 1946 to the present. It's an essential resource for healthcare professionals, researchers, and students in the biomedical field.

Health Level Seven (HL7) is a set of international standards for the transfer of clinical and administrative data between software applications used by various healthcare providers. The standards are developed and maintained by Health Level Seven International, an organization accredited by the American National Standards Institute.

The HL7 standards define the structure and format of the messages that are exchanged between different systems, such as electronic health records (EHRs), laboratory information systems, and radiology information systems. The messages contain clinical data, such as patient demographics, medication orders, and test results, as well as administrative data, such as billing information.

The HL7 standards are designed to be flexible and extensible, allowing for the integration of new data elements and message types as needed. They support a wide range of communication protocols, including file-based exchange, messaging using TCP/IP, and web services.

By providing a standardized way of exchanging healthcare data, HL7 helps to improve the efficiency and accuracy of care delivery, reduce costs, and enhance patient safety. It also facilitates the integration of disparate systems and enables the sharing of clinical data across different healthcare organizations.

A Computerized Medical Record System (CMRS) is a digital version of a patient's paper chart. It contains all of the patient's medical history from multiple providers and can be shared securely between healthcare professionals. A CMRS includes a range of data such as demographics, progress notes, problems, medications, vital signs, past medical history, immunizations, laboratory data, and radiology reports. The system facilitates the storage, retrieval, and exchange of this information in an efficient manner, and can also provide decision support, alerts, reminders, and tools for performing data analysis and creating reports. It is designed to improve the quality, safety, and efficiency of healthcare delivery by providing accurate, up-to-date, and comprehensive information about patients at the point of care.

A database, in the context of medical informatics, is a structured set of data organized in a way that allows for efficient storage, retrieval, and analysis. Databases are used extensively in healthcare to store and manage various types of information, including patient records, clinical trials data, research findings, and genetic data.

As a topic, "Databases" in medicine can refer to the design, implementation, management, and use of these databases. It may also encompass issues related to data security, privacy, and interoperability between different healthcare systems and databases. Additionally, it can involve the development and application of database technologies for specific medical purposes, such as clinical decision support, outcomes research, and personalized medicine.

Overall, databases play a critical role in modern healthcare by enabling evidence-based practice, improving patient care, advancing medical research, and informing health policy decisions.

PubMed is not a medical condition or term, but rather a biomedical literature search engine and database maintained by the National Center for Biotechnology Information (NCBI), a division of the U.S. National Library of Medicine (NLM). It provides access to life sciences literature, including journal articles in medicine, nursing, dentistry, veterinary medicine, health care systems, and preclinical sciences.

PubMed contains more than 30 million citations and abstracts from MEDLINE, life science journals, and online books. Many of the citations include links to full-text articles on publishers' websites or through NCBI's DocSumo service. Researchers, healthcare professionals, students, and the general public use PubMed to find relevant and reliable information in the biomedical literature for research, education, and patient care purposes.

"Subject Headings" is not a medical term per se, but rather a term used in the field of library science and information management. Subject headings are standardized terms or phrases used to describe the subject or content of a document, such as a book, article, or research paper, in a consistent and controlled way. They help organize and retrieve information by providing a uniform vocabulary for indexing and searching.

In the medical field, subject headings may be used in databases like PubMed, Medline, and CINAHL to categorize and search for medical literature. For example, the National Library of Medicine's MeSH (Medical Subject Headings) is a controlled vocabulary used for indexing and searching biomedical literature. It includes headings for various medical concepts, such as diseases, treatments, anatomical structures, and procedures, which can be used to search for relevant articles in PubMed and other databases.

An algorithm is not a medical term, but rather a concept from computer science and mathematics. In the context of medicine, algorithms are often used to describe step-by-step procedures for diagnosing or managing medical conditions. These procedures typically involve a series of rules or decision points that help healthcare professionals make informed decisions about patient care.

For example, an algorithm for diagnosing a particular type of heart disease might involve taking a patient's medical history, performing a physical exam, ordering certain diagnostic tests, and interpreting the results in a specific way. By following this algorithm, healthcare professionals can ensure that they are using a consistent and evidence-based approach to making a diagnosis.

Algorithms can also be used to guide treatment decisions. For instance, an algorithm for managing diabetes might involve setting target blood sugar levels, recommending certain medications or lifestyle changes based on the patient's individual needs, and monitoring the patient's response to treatment over time.

Overall, algorithms are valuable tools in medicine because they help standardize clinical decision-making and ensure that patients receive high-quality care based on the latest scientific evidence.

I'm sorry for any confusion, but "Microcomputers" is not a term commonly used in medical definitions. Microcomputers are small computers with a microprocessor as the central processing unit. They are widely used in various settings, including healthcare, to perform tasks such as data management, analysis, and patient record keeping. However, the term itself does not have a specific medical connotation. If you have any questions related to technology use in healthcare, I'd be happy to try to help with those!

Computational biology is a branch of biology that uses mathematical and computational methods to study biological data, models, and processes. It involves the development and application of algorithms, statistical models, and computational approaches to analyze and interpret large-scale molecular and phenotypic data from genomics, transcriptomics, proteomics, metabolomics, and other high-throughput technologies. The goal is to gain insights into biological systems and processes, develop predictive models, and inform experimental design and hypothesis testing in the life sciences. Computational biology encompasses a wide range of disciplines, including bioinformatics, systems biology, computational genomics, network biology, and mathematical modeling of biological systems.

A protein database is a type of biological database that contains information about proteins and their structures, functions, sequences, and interactions with other molecules. These databases can include experimentally determined data, such as protein sequences derived from DNA sequencing or mass spectrometry, as well as predicted data based on computational methods.

Some examples of protein databases include:

1. UniProtKB: a comprehensive protein database that provides information about protein sequences, functions, and structures, as well as literature references and links to other resources.
2. PDB (Protein Data Bank): a database of three-dimensional protein structures determined by experimental methods such as X-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy.
3. BLAST (Basic Local Alignment Search Tool): a web-based tool that allows users to compare a query protein sequence against a protein database to identify similar sequences and potential functional relationships.
4. InterPro: a database of protein families, domains, and functional sites that provides information about protein function based on sequence analysis and other data.
5. STRING (Search Tool for the Retrieval of Interacting Genes/Proteins): a database of known and predicted protein-protein interactions, including physical and functional associations.

Protein databases are essential tools in proteomics research, enabling researchers to study protein function, evolution, and interaction networks on a large scale.

Abstracting and indexing are processes used in the field of information science to organize, summarize, and categorize published literature, making it easier for researchers and other interested individuals to find and access relevant information.

Abstracting involves creating a brief summary of a publication, typically no longer than a few hundred words, that captures its key points and findings. This summary is known as an abstract and provides readers with a quick overview of the publication's content, allowing them to determine whether it is worth reading in full.

Indexing, on the other hand, involves categorizing publications according to their subject matter, using a controlled vocabulary or set of keywords. This makes it easier for users to search for and find publications on specific topics, as they can simply look up the relevant keyword or subject heading in the index.

Together, abstracting and indexing are essential tools for managing the vast and growing amount of published literature in any given field. They help ensure that important research findings and other information are easily discoverable and accessible to those who need them, thereby facilitating the dissemination of knowledge and advancing scientific progress.

An Electronic Health Record (EHR) is a digital version of a patient's medical history that is stored and maintained electronically rather than on paper. It contains comprehensive information about a patient's health status, including their medical history, medications, allergies, test results, immunization records, and other relevant health information. EHRs can be shared among authorized healthcare providers, which enables better coordination of care, improved patient safety, and more efficient delivery of healthcare services.

EHRs are designed to provide real-time, patient-centered records that make it easier for healthcare providers to access up-to-date and accurate information about their patients. They can also help reduce errors, prevent duplicative tests and procedures, and improve communication among healthcare providers. EHRs may include features such as clinical decision support tools, which can alert healthcare providers to potential drug interactions or other health risks based on a patient's medical history.

EHRs are subject to various regulations and standards to ensure the privacy and security of patients' health information. In the United States, for example, EHRs must comply with the Health Insurance Portability and Accountability Act (HIPAA) Privacy Rule, which sets national standards for the protection of personal health information.

Pharmaceutical preparations refer to the various forms of medicines that are produced by pharmaceutical companies, which are intended for therapeutic or prophylactic use. These preparations consist of an active ingredient (the drug) combined with excipients (inactive ingredients) in a specific formulation and dosage form.

The active ingredient is the substance that has a therapeutic effect on the body, while the excipients are added to improve the stability, palatability, bioavailability, or administration of the drug. Examples of pharmaceutical preparations include tablets, capsules, solutions, suspensions, emulsions, ointments, creams, and injections.

The production of pharmaceutical preparations involves a series of steps that ensure the quality, safety, and efficacy of the final product. These steps include the selection and testing of raw materials, formulation development, manufacturing, packaging, labeling, and storage. Each step is governed by strict regulations and guidelines to ensure that the final product meets the required standards for use in medical practice.

A genetic database is a type of biomedical or health informatics database that stores and organizes genetic data, such as DNA sequences, gene maps, genotypes, haplotypes, and phenotype information. These databases can be used for various purposes, including research, clinical diagnosis, and personalized medicine.

There are different types of genetic databases, including:

1. Genomic databases: These databases store whole genome sequences, gene expression data, and other genomic information. Examples include the National Center for Biotechnology Information's (NCBI) GenBank, the European Nucleotide Archive (ENA), and the DNA Data Bank of Japan (DDBJ).
2. Gene databases: These databases contain information about specific genes, including their location, function, regulation, and evolution. Examples include the Online Mendelian Inheritance in Man (OMIM) database, the Universal Protein Resource (UniProt), and the Gene Ontology (GO) database.
3. Variant databases: These databases store information about genetic variants, such as single nucleotide polymorphisms (SNPs), insertions/deletions (INDELs), and copy number variations (CNVs). Examples include the Database of Single Nucleotide Polymorphisms (dbSNP), the Catalogue of Somatic Mutations in Cancer (COSMIC), and the International HapMap Project.
4. Clinical databases: These databases contain genetic and clinical information about patients, such as their genotype, phenotype, family history, and response to treatments. Examples include the ClinVar database, the Pharmacogenomics Knowledgebase (PharmGKB), and the Genetic Testing Registry (GTR).
5. Population databases: These databases store genetic information about different populations, including their ancestry, demographics, and genetic diversity. Examples include the 1000 Genomes Project, the Human Genome Diversity Project (HGDP), and the Allele Frequency Net Database (AFND).

Genetic databases can be publicly accessible or restricted to authorized users, depending on their purpose and content. They play a crucial role in advancing our understanding of genetics and genomics, as well as improving healthcare and personalized medicine.

Pharmacogenetics is a branch of pharmacology that deals with the study of genetic factors that influence an individual's response to drugs. It involves the examination of how variations in genes encoding drug-metabolizing enzymes, transporters, receptors, and other targets affect drug absorption, distribution, metabolism, excretion, and efficacy, as well as the incidence and severity of adverse reactions.

The goal of pharmacogenetics is to optimize drug therapy by tailoring it to an individual's genetic makeup, thereby improving treatment outcomes, reducing adverse effects, and minimizing healthcare costs. This field has significant implications for personalized medicine, as it may help identify patients who are more likely to benefit from certain medications or who are at increased risk of toxicity, allowing for more informed prescribing decisions.

A computer system is a collection of hardware and software components that work together to perform specific tasks. This includes the physical components such as the central processing unit (CPU), memory, storage devices, and input/output devices, as well as the operating system and application software that run on the hardware. Computer systems can range from small, embedded systems found in appliances and devices, to large, complex networks of interconnected computers used for enterprise-level operations.

In a medical context, computer systems are often used for tasks such as storing and retrieving electronic health records (EHRs), managing patient scheduling and billing, performing diagnostic imaging and analysis, and delivering telemedicine services. These systems must adhere to strict regulatory standards, such as the Health Insurance Portability and Accountability Act (HIPAA) in the United States, to ensure the privacy and security of sensitive medical information.

Decision support techniques are methods used to help individuals or groups make informed and effective decisions in a medical context. These techniques can involve various approaches, such as:

1. **Clinical Decision Support Systems (CDSS):** Computerized systems that provide clinicians with patient-specific information and evidence-based recommendations to assist in decision-making. CDSS can be integrated into electronic health records (EHRs) or standalone applications.

2. **Evidence-Based Medicine (EBM):** A systematic approach to clinical decision-making that involves the integration of best available research evidence, clinician expertise, and patient values and preferences. EBM emphasizes the importance of using high-quality scientific studies to inform medical decisions.

3. **Diagnostic Reasoning:** The process of formulating a diagnosis based on history, physical examination, and diagnostic tests. Diagnostic reasoning techniques may include pattern recognition, hypothetico-deductive reasoning, or a combination of both.

4. **Predictive Modeling:** The use of statistical models to predict patient outcomes based on historical data and clinical variables. These models can help clinicians identify high-risk patients and inform treatment decisions.

5. **Cost-Effectiveness Analysis (CEA):** An economic evaluation technique that compares the costs and benefits of different medical interventions to determine which option provides the most value for money. CEA can assist decision-makers in allocating resources efficiently.

6. **Multicriteria Decision Analysis (MCDA):** A structured approach to decision-making that involves identifying, evaluating, and comparing multiple criteria or objectives. MCDA can help clinicians and patients make complex decisions by accounting for various factors, such as efficacy, safety, cost, and patient preferences.

7. **Shared Decision-Making (SDM):** A collaborative approach to decision-making that involves the clinician and patient working together to choose the best course of action based on the available evidence, clinical expertise, and patient values and preferences. SDM aims to empower patients to participate actively in their care.

These techniques can be used individually or in combination to support medical decision-making and improve patient outcomes.

I must clarify that there is no specific medical definition for "Software Design." Software design is a term used in the field of software engineering and development, which includes the creation of detailed plans, schemas, and models that describe how a software system or application should be constructed and implemented. This process involves various activities such as defining the architecture, components, modules, interfaces, data structures, and algorithms required to build the software system.

However, in the context of medical software or healthcare applications, software design would still refer to the planning and structuring of the software system but with a focus on addressing specific needs and challenges within the medical domain. This might include considerations for data privacy and security, regulatory compliance (such as HIPAA or GDPR), integration with existing health IT systems, user experience (UX) design for healthcare professionals and patients, and evidence-based decision support features.

A Medical Order Entry System (MOES) is a computer-based tool that allows healthcare professionals to enter, modify, review, and communicate orders for patients' medications, tests, or other treatments in a structured and standardized electronic format. MOES are designed to improve the safety, efficiency, and legibility of medical orders, reducing the risk of medication errors and improving overall patient care. These systems can be integrated with other healthcare information systems, such as electronic health records (EHRs), to provide a seamless and coordinated approach to patient care.

A Hospital Information System (HIS) is a comprehensive, integrated set of software solutions that support the management and operation of a hospital or healthcare facility. It typically includes various modules such as:

1. Electronic Health Record (EHR): A digital version of a patient's paper chart that contains all of their medical history from one or multiple providers.
2. Computerized Physician Order Entry (CPOE): A system that allows physicians to enter, modify, review, and communicate orders for tests, medications, and other treatments electronically.
3. Pharmacy Information System: A system that manages the medication use process, including ordering, dispensing, administering, and monitoring of medications.
4. Laboratory Information System (LIS): A system that automates and manages the laboratory testing process, from order entry to result reporting.
5. Radiology Information System (RIS): A system that manages medical imaging data, including scheduling, image acquisition, storage, and retrieval.
6. Picture Archiving and Communication System (PACS): A system that stores, distributes, and displays medical images from various modalities such as X-ray, CT, MRI, etc.
7. Admission, Discharge, and Transfer (ADT) system: A system that manages patient registration, scheduling, and tracking of their progress through the hospital.
8. Financial Management System: A system that handles billing, coding, and reimbursement processes.
9. Materials Management System: A system that tracks inventory, supply chain, and logistics operations within a healthcare facility.
10. Nursing Documentation System: A system that supports the documentation of nursing care, including assessments, interventions, and outcomes.

These systems are designed to improve the efficiency, quality, and safety of patient care by facilitating communication, coordination, and data sharing among healthcare providers and departments.

In a medical context, documentation refers to the process of recording and maintaining written or electronic records of a patient's health status, medical history, treatment plans, medications, and other relevant information. The purpose of medical documentation is to provide clear and accurate communication among healthcare providers, to support clinical decision-making, to ensure continuity of care, to meet legal and regulatory requirements, and to facilitate research and quality improvement initiatives.

Medical documentation typically includes various types of records such as:

1. Patient's demographic information, including name, date of birth, gender, and contact details.
2. Medical history, including past illnesses, surgeries, allergies, and family medical history.
3. Physical examination findings, laboratory and diagnostic test results, and diagnoses.
4. Treatment plans, including medications, therapies, procedures, and follow-up care.
5. Progress notes, which document the patient's response to treatment and any changes in their condition over time.
6. Consultation notes, which record communication between healthcare providers regarding a patient's care.
7. Discharge summaries, which provide an overview of the patient's hospital stay, including diagnoses, treatments, and follow-up plans.

Medical documentation must be clear, concise, accurate, and timely, and it should adhere to legal and ethical standards. Healthcare providers are responsible for maintaining the confidentiality of patients' medical records and ensuring that they are accessible only to authorized personnel.

Computer-Assisted Instruction (CAI) is a type of educational technology that involves the use of computers to deliver, support, and enhance learning experiences. In a medical context, CAI can be used to teach a variety of topics, including anatomy, physiology, pharmacology, and clinical skills.

CAI typically involves interactive multimedia presentations, simulations, quizzes, and other activities that engage learners and provide feedback on their performance. It may also include adaptive learning systems that adjust the content and pace of instruction based on the learner's abilities and progress.

CAI has been shown to be effective in improving knowledge retention, critical thinking skills, and learner satisfaction in medical education. It can be used as a standalone teaching method or in combination with traditional classroom instruction or clinical experiences.

Medical Informatics, also known as Healthcare Informatics, is the scientific discipline that deals with the systematic processing and analysis of data, information, and knowledge in healthcare and biomedicine. It involves the development and application of theories, methods, and tools to create, acquire, store, retrieve, share, use, and reuse health-related data and knowledge for clinical, educational, research, and administrative purposes. Medical Informatics encompasses various areas such as bioinformatics, clinical informatics, consumer health informatics, public health informatics, and translational bioinformatics. It aims to improve healthcare delivery, patient outcomes, and biomedical research through the effective use of information technology and data management strategies.

A disease is a condition that impairs normal functioning and causes harm to the body. It is typically characterized by a specific set of symptoms and may be caused by genetic, environmental, or infectious agents. A disease can also be described as a disorder of structure or function in an organism that produces specific signs or symptoms. Diseases can range from minor ones, like the common cold, to serious illnesses, such as heart disease or cancer. They can also be acute, with a sudden onset and short duration, or chronic, lasting for a long period of time. Ultimately, a disease is any deviation from normal homeostasis that causes harm to an organism.

Computer graphics is the field of study and practice related to creating images and visual content using computer technology. It involves various techniques, algorithms, and tools for generating, manipulating, and rendering digital images and models. These can include 2D and 3D modeling, animation, rendering, visualization, and image processing. Computer graphics is used in a wide range of applications, including video games, movies, scientific simulations, medical imaging, architectural design, and data visualization.

Computer communication networks (CCN) refer to the interconnected systems or groups of computers that are able to communicate and share resources and information with each other. These networks may be composed of multiple interconnected devices, including computers, servers, switches, routers, and other hardware components. The connections between these devices can be established through various types of media, such as wired Ethernet cables or wireless Wi-Fi signals.

CCNs enable the sharing of data, applications, and services among users and devices, and they are essential for supporting modern digital communication and collaboration. Some common examples of CCNs include local area networks (LANs), wide area networks (WANs), and the Internet. These networks can be designed and implemented in various topologies, such as star, ring, bus, mesh, and tree configurations, to meet the specific needs and requirements of different organizations and applications.

Anatomic models are three-dimensional representations of body structures used for educational, training, or demonstration purposes. They can be made from various materials such as plastic, wax, or rubber and may depict the entire body or specific regions, organs, or systems. These models can be used to provide a visual aid for understanding anatomy, physiology, and pathology, and can be particularly useful in situations where actual human specimens are not available or practical to use. They may also be used for surgical planning and rehearsal, as well as in medical research and product development.

The skull base is the lower part of the skull that forms the floor of the cranial cavity and the roof of the facial skeleton. It is a complex anatomical region composed of several bones, including the frontal, sphenoid, temporal, occipital, and ethmoid bones. The skull base supports the brain and contains openings for blood vessels and nerves that travel between the brain and the face or neck. The skull base can be divided into three regions: the anterior cranial fossa, middle cranial fossa, and posterior cranial fossa, which house different parts of the brain.

Genomics is the scientific study of genes and their functions. It involves the sequencing and analysis of an organism's genome, which is its complete set of DNA, including all of its genes. Genomics also includes the study of how genes interact with each other and with the environment. This field of study can provide important insights into the genetic basis of diseases and can lead to the development of new diagnostic tools and treatments.

I'm sorry for any confusion, but "Online Systems" is not a medical term. It generally refers to computer systems or networks that are connected to the internet and can be accessed remotely. In a medical context, it could refer to various online tools and platforms used in healthcare, such as electronic health records, telemedicine systems, or medical research databases. However, without more specific context, it's difficult to provide an accurate medical definition.

Clinical competence is the ability of a healthcare professional to provide safe and effective patient care, demonstrating the knowledge, skills, and attitudes required for the job. It involves the integration of theoretical knowledge with practical skills, judgment, and decision-making abilities in real-world clinical situations. Clinical competence is typically evaluated through various methods such as direct observation, case studies, simulations, and feedback from peers and supervisors.

A clinically competent healthcare professional should be able to:

1. Demonstrate a solid understanding of the relevant medical knowledge and its application in clinical practice.
2. Perform essential clinical skills proficiently and safely.
3. Communicate effectively with patients, families, and other healthcare professionals.
4. Make informed decisions based on critical thinking and problem-solving abilities.
5. Exhibit professionalism, ethical behavior, and cultural sensitivity in patient care.
6. Continuously evaluate and improve their performance through self-reflection and ongoing learning.

Maintaining clinical competence is essential for healthcare professionals to ensure the best possible outcomes for their patients and stay current with advances in medical science and technology.

Base composition in genetics refers to the relative proportion of the four nucleotide bases (adenine, thymine, guanine, and cytosine) in a DNA or RNA molecule. In DNA, adenine pairs with thymine, and guanine pairs with cytosine, so the base composition is often expressed in terms of the ratio of adenine + thymine (A-T) to guanine + cytosine (G-C). This ratio can vary between species and even between different regions of the same genome. The base composition can provide important clues about the function, evolution, and structure of genetic material.

A Schiff base is not a medical term per se, but rather a chemical concept that can be relevant in various scientific and medical fields. A Schiff base is a chemical compound that contains a carbon-nitrogen double bond with the nitrogen atom connected to an aryl or alkyl group, excluding hydrogen. This structure is also known as an azomethine.

The general formula for a Schiff base is R1R2C=NR3, where R1 and R2 are organic groups (aryl or alkyl), and R3 is a hydrogen atom or an organic group. These compounds can be synthesized by the condensation of a primary amine with a carbonyl compound, such as an aldehyde or ketone.

Schiff bases have been studied in various medical and biological contexts due to their potential bioactivities. Some Schiff bases exhibit antimicrobial, antifungal, anti-inflammatory, and anticancer properties. They can also serve as ligands for metal ions, forming complexes with potential applications in medicinal chemistry, such as in the development of new drugs or diagnostic agents.

Practice guidelines, also known as clinical practice guidelines, are systematically developed statements that aim to assist healthcare professionals and patients in making informed decisions about appropriate health care for specific clinical circumstances. They are based on a thorough evaluation of the available scientific evidence, consensus of expert opinion, and consideration of patient preferences. Practice guidelines can cover a wide range of topics, including diagnosis, management, prevention, and treatment options for various medical conditions. They are intended to improve the quality and consistency of care, reduce unnecessary variations in practice, and promote evidence-based medicine. However, they should not replace clinical judgment or individualized patient care.

Internal Medicine is a medical specialty that deals with the prevention, diagnosis, and treatment of internal diseases affecting adults. It encompasses a wide range of medical conditions, including those related to the cardiovascular, respiratory, gastrointestinal, hematological, endocrine, infectious, and immune systems. Internists, or general internists, are trained to provide comprehensive care for adult patients, managing both simple and complex diseases, and often serving as primary care physicians. They may also subspecialize in various fields such as cardiology, gastroenterology, nephrology, or infectious disease, among others.

In the context of medical education, a curriculum refers to the planned and organized sequence of experiences and learning opportunities designed to achieve specific educational goals and objectives. It outlines the knowledge, skills, and attitudes that medical students or trainees are expected to acquire during their training program. The curriculum may include various components such as lectures, small group discussions, clinical rotations, simulations, and other experiential learning activities. It is typically developed and implemented by medical education experts and faculty members in consultation with stakeholders, including learners, practitioners, and patients.

I'm sorry for any confusion, but "United States" is a geopolitical entity, specifically the name of the country consisting of 50 states, and it is not a medical term or concept. Therefore, I can't provide a medical definition for it. If you have any questions related to health, medicine, or biology, I would be happy to try to help answer those!

Metabolic networks and pathways refer to the complex interconnected series of biochemical reactions that occur within cells to maintain life. These reactions are catalyzed by enzymes and are responsible for the conversion of nutrients into energy, as well as the synthesis and breakdown of various molecules required for cellular function.

A metabolic pathway is a series of chemical reactions that occur in a specific order, with each reaction being catalyzed by a different enzyme. These pathways are often interconnected, forming a larger network of interactions known as a metabolic network.

Metabolic networks can be represented as complex diagrams or models, which show the relationships between different pathways and the flow of matter and energy through the system. These networks can help researchers to understand how cells regulate their metabolism in response to changes in their environment, and how disruptions to these networks can lead to disease.

Some common examples of metabolic pathways include glycolysis, the citric acid cycle (also known as the Krebs cycle), and the pentose phosphate pathway. Each of these pathways plays a critical role in maintaining cellular homeostasis and providing energy for cellular functions.

Educational measurement is a field of study concerned with the development, administration, and interpretation of tests, questionnaires, and other assessments for the purpose of measuring learning outcomes, abilities, knowledge, skills, and attitudes in an educational context. The goal of educational measurement is to provide valid, reliable, and fair measures of student achievement and growth that can inform instructional decisions, guide curriculum development, and support accountability efforts.

Educational measurement involves a variety of statistical and psychometric methods for analyzing assessment data, including classical test theory, item response theory, and generalizability theory. These methods are used to establish the reliability and validity of assessments, as well as to score and interpret student performance. Additionally, educational measurement is concerned with issues related to test fairness, accessibility, and bias, and seeks to ensure that assessments are equitable and inclusive for all students.

Overall, educational measurement plays a critical role in ensuring the quality and effectiveness of educational programs and policies, and helps to promote student learning and achievement.

Automated Pattern Recognition in a medical context refers to the use of computer algorithms and artificial intelligence techniques to identify, classify, and analyze specific patterns or trends in medical data. This can include recognizing visual patterns in medical images, such as X-rays or MRIs, or identifying patterns in large datasets of physiological measurements or electronic health records.

The goal of automated pattern recognition is to assist healthcare professionals in making more accurate diagnoses, monitoring disease progression, and developing personalized treatment plans. By automating the process of pattern recognition, it can help reduce human error, increase efficiency, and improve patient outcomes.

Examples of automated pattern recognition in medicine include using machine learning algorithms to identify early signs of diabetic retinopathy in eye scans or detecting abnormal heart rhythms in electrocardiograms (ECGs). These techniques can also be used to predict patient risk based on patterns in their medical history, such as identifying patients who are at high risk for readmission to the hospital.

A questionnaire in the medical context is a standardized, systematic, and structured tool used to gather information from individuals regarding their symptoms, medical history, lifestyle, or other health-related factors. It typically consists of a series of written questions that can be either self-administered or administered by an interviewer. Questionnaires are widely used in various areas of healthcare, including clinical research, epidemiological studies, patient care, and health services evaluation to collect data that can inform diagnosis, treatment planning, and population health management. They provide a consistent and organized method for obtaining information from large groups or individual patients, helping to ensure accurate and comprehensive data collection while minimizing bias and variability in the information gathered.

I'm sorry for any confusion, but "organizational innovation" is not a term that has a specific medical definition. It is a concept that is more commonly used in the fields of business and management, where it refers to the introduction of new methods, ideas, or products within an organization. This can include things like new processes, structures, or technologies that are designed to improve efficiency, effectiveness, or competitive advantage.

In healthcare organizations, for example, organizational innovation might involve the implementation of new electronic health records systems, the creation of multidisciplinary care teams, or the adoption of novel approaches to patient engagement and empowerment. These types of innovations can help to improve patient outcomes, reduce costs, and enhance the overall quality of care.

Patient education, as defined by the US National Library of Medicine's Medical Subject Headings (MeSH), is "the teaching or training of patients concerning their own health needs. It includes the patient's understanding of his or her condition and the necessary procedures for self, assisted, or professional care." This encompasses a wide range of activities and interventions aimed at helping patients and their families understand their medical conditions, treatment options, self-care skills, and overall health management. Effective patient education can lead to improved health outcomes, increased patient satisfaction, and better use of healthcare resources.

Biological models, also known as physiological models or organismal models, are simplified representations of biological systems, processes, or mechanisms that are used to understand and explain the underlying principles and relationships. These models can be theoretical (conceptual or mathematical) or physical (such as anatomical models, cell cultures, or animal models). They are widely used in biomedical research to study various phenomena, including disease pathophysiology, drug action, and therapeutic interventions.

Examples of biological models include:

1. Mathematical models: These use mathematical equations and formulas to describe complex biological systems or processes, such as population dynamics, metabolic pathways, or gene regulation networks. They can help predict the behavior of these systems under different conditions and test hypotheses about their underlying mechanisms.
2. Cell cultures: These are collections of cells grown in a controlled environment, typically in a laboratory dish or flask. They can be used to study cellular processes, such as signal transduction, gene expression, or metabolism, and to test the effects of drugs or other treatments on these processes.
3. Animal models: These are living organisms, usually vertebrates like mice, rats, or non-human primates, that are used to study various aspects of human biology and disease. They can provide valuable insights into the pathophysiology of diseases, the mechanisms of drug action, and the safety and efficacy of new therapies.
4. Anatomical models: These are physical representations of biological structures or systems, such as plastic models of organs or tissues, that can be used for educational purposes or to plan surgical procedures. They can also serve as a basis for developing more sophisticated models, such as computer simulations or 3D-printed replicas.

Overall, biological models play a crucial role in advancing our understanding of biology and medicine, helping to identify new targets for therapeutic intervention, develop novel drugs and treatments, and improve human health.

"Evaluation studies" is a broad term that refers to the systematic assessment or examination of a program, project, policy, intervention, or product. The goal of an evaluation study is to determine its merits, worth, and value by measuring its effects, efficiency, and impact. There are different types of evaluation studies, including formative evaluations (conducted during the development or implementation of a program to provide feedback for improvement), summative evaluations (conducted at the end of a program to determine its overall effectiveness), process evaluations (focusing on how a program is implemented and delivered), outcome evaluations (assessing the short-term and intermediate effects of a program), and impact evaluations (measuring the long-term and broad consequences of a program).

In medical contexts, evaluation studies are often used to assess the safety, efficacy, and cost-effectiveness of new treatments, interventions, or technologies. These studies can help healthcare providers make informed decisions about patient care, guide policymakers in developing evidence-based policies, and promote accountability and transparency in healthcare systems. Examples of evaluation studies in medicine include randomized controlled trials (RCTs) that compare the outcomes of a new treatment to those of a standard or placebo treatment, observational studies that examine the real-world effectiveness and safety of interventions, and economic evaluations that assess the costs and benefits of different healthcare options.

Research, in the context of medicine, is a systematic and rigorous process of collecting, analyzing, and interpreting information in order to increase our understanding, develop new knowledge, or evaluate current practices and interventions. It can involve various methodologies such as observational studies, experiments, surveys, or literature reviews. The goal of medical research is to advance health care by identifying new treatments, improving diagnostic techniques, and developing prevention strategies. Medical research is typically conducted by teams of researchers including clinicians, scientists, and other healthcare professionals. It is subject to ethical guidelines and regulations to ensure that it is conducted responsibly and with the best interests of patients in mind.

Systems Biology is a multidisciplinary approach to studying biological systems that involves the integration of various scientific disciplines such as biology, mathematics, physics, computer science, and engineering. It aims to understand how biological components, including genes, proteins, metabolites, cells, and organs, interact with each other within the context of the whole system. This approach emphasizes the emergent properties of biological systems that cannot be explained by studying individual components alone. Systems biology often involves the use of computational models to simulate and predict the behavior of complex biological systems and to design experiments for testing hypotheses about their functioning. The ultimate goal of systems biology is to develop a more comprehensive understanding of how biological systems function, with applications in fields such as medicine, agriculture, and bioengineering.

Gene Regulatory Networks (GRNs) are complex systems of molecular interactions that regulate the expression of genes within an organism. These networks consist of various types of regulatory elements, including transcription factors, enhancers, promoters, and silencers, which work together to control when, where, and to what extent a gene is expressed.

In GRNs, transcription factors bind to specific DNA sequences in the regulatory regions of target genes, either activating or repressing their transcription into messenger RNA (mRNA). This process is influenced by various intracellular and extracellular signals that modulate the activity of transcription factors, allowing for precise regulation of gene expression in response to changing environmental conditions.

The structure and behavior of GRNs can be represented as a network of nodes (genes) and edges (regulatory interactions), with the strength and directionality of these interactions determined by the specific molecular mechanisms involved. Understanding the organization and dynamics of GRNs is crucial for elucidating the underlying causes of various biological processes, including development, differentiation, homeostasis, and disease.

Data collection in the medical context refers to the systematic gathering of information relevant to a specific research question or clinical situation. This process involves identifying and recording data elements, such as demographic characteristics, medical history, physical examination findings, laboratory results, and imaging studies, from various sources including patient interviews, medical records, and diagnostic tests. The data collected is used to support clinical decision-making, inform research hypotheses, and evaluate the effectiveness of treatments or interventions. It is essential that data collection is performed in a standardized and unbiased manner to ensure the validity and reliability of the results.

A phenotype is the physical or biochemical expression of an organism's genes, or the observable traits and characteristics resulting from the interaction of its genetic constitution (genotype) with environmental factors. These characteristics can include appearance, development, behavior, and resistance to disease, among others. Phenotypes can vary widely, even among individuals with identical genotypes, due to differences in environmental influences, gene expression, and genetic interactions.

A computer simulation is a process that involves creating a model of a real-world system or phenomenon on a computer and then using that model to run experiments and make predictions about how the system will behave under different conditions. In the medical field, computer simulations are used for a variety of purposes, including:

1. Training and education: Computer simulations can be used to create realistic virtual environments where medical students and professionals can practice their skills and learn new procedures without risk to actual patients. For example, surgeons may use simulation software to practice complex surgical techniques before performing them on real patients.
2. Research and development: Computer simulations can help medical researchers study the behavior of biological systems at a level of detail that would be difficult or impossible to achieve through experimental methods alone. By creating detailed models of cells, tissues, organs, or even entire organisms, researchers can use simulation software to explore how these systems function and how they respond to different stimuli.
3. Drug discovery and development: Computer simulations are an essential tool in modern drug discovery and development. By modeling the behavior of drugs at a molecular level, researchers can predict how they will interact with their targets in the body and identify potential side effects or toxicities. This information can help guide the design of new drugs and reduce the need for expensive and time-consuming clinical trials.
4. Personalized medicine: Computer simulations can be used to create personalized models of individual patients based on their unique genetic, physiological, and environmental characteristics. These models can then be used to predict how a patient will respond to different treatments and identify the most effective therapy for their specific condition.

Overall, computer simulations are a powerful tool in modern medicine, enabling researchers and clinicians to study complex systems and make predictions about how they will behave under a wide range of conditions. By providing insights into the behavior of biological systems at a level of detail that would be difficult or impossible to achieve through experimental methods alone, computer simulations are helping to advance our understanding of human health and disease.

A research design in medical or healthcare research is a systematic plan that guides the execution and reporting of research to address a specific research question or objective. It outlines the overall strategy for collecting, analyzing, and interpreting data to draw valid conclusions. The design includes details about the type of study (e.g., experimental, observational), sampling methods, data collection techniques, data analysis approaches, and any potential sources of bias or confounding that need to be controlled for. A well-defined research design helps ensure that the results are reliable, generalizable, and relevant to the research question, ultimately contributing to evidence-based practice in medicine and healthcare.

Reproducibility of results in a medical context refers to the ability to obtain consistent and comparable findings when a particular experiment or study is repeated, either by the same researcher or by different researchers, following the same experimental protocol. It is an essential principle in scientific research that helps to ensure the validity and reliability of research findings.

In medical research, reproducibility of results is crucial for establishing the effectiveness and safety of new treatments, interventions, or diagnostic tools. It involves conducting well-designed studies with adequate sample sizes, appropriate statistical analyses, and transparent reporting of methods and findings to allow other researchers to replicate the study and confirm or refute the results.

The lack of reproducibility in medical research has become a significant concern in recent years, as several high-profile studies have failed to produce consistent findings when replicated by other researchers. This has led to increased scrutiny of research practices and a call for greater transparency, rigor, and standardization in the conduct and reporting of medical research.

Molecular sequence data refers to the specific arrangement of molecules, most commonly nucleotides in DNA or RNA, or amino acids in proteins, that make up a biological macromolecule. This data is generated through laboratory techniques such as sequencing, and provides information about the exact order of the constituent molecules. This data is crucial in various fields of biology, including genetics, evolution, and molecular biology, allowing for comparisons between different organisms, identification of genetic variations, and studies of gene function and regulation.

A human genome is the complete set of genetic information contained within the 23 pairs of chromosomes found in the nucleus of most human cells. It includes all of the genes, which are segments of DNA that contain the instructions for making proteins, as well as non-coding regions of DNA that regulate gene expression and provide structural support to the chromosomes.

The human genome contains approximately 3 billion base pairs of DNA and is estimated to contain around 20,000-25,000 protein-coding genes. The sequencing of the human genome was completed in 2003 as part of the Human Genome Project, which has had a profound impact on our understanding of human biology, disease, and evolution.

The proteome is the entire set of proteins produced or present in an organism, system, organ, or cell at a certain time under specific conditions. It is a dynamic collection of protein species that changes over time, responding to various internal and external stimuli such as disease, stress, or environmental factors. The study of the proteome, known as proteomics, involves the identification and quantification of these protein components and their post-translational modifications, providing valuable insights into biological processes, functional pathways, and disease mechanisms.

Proteomics is the large-scale study and analysis of proteins, including their structures, functions, interactions, modifications, and abundance, in a given cell, tissue, or organism. It involves the identification and quantification of all expressed proteins in a biological sample, as well as the characterization of post-translational modifications, protein-protein interactions, and functional pathways. Proteomics can provide valuable insights into various biological processes, diseases, and drug responses, and has applications in basic research, biomedicine, and clinical diagnostics. The field combines various techniques from molecular biology, chemistry, physics, and bioinformatics to study proteins at a systems level.

I'm sorry for any confusion, but "Knowledge Management" is not a term that has a specific medical definition. Knowledge Management is a broader business and academic concept that refers to the process of creating, sharing, using, and managing the knowledge and information within an organization. It involves the strategies and practices used by organizations to identify, create, represent, distribute, and enable the adoption of insights and experiences. These principles can be applied in various fields, including healthcare, to improve decision-making, efficiency, and patient care. However, there is no unique medical definition for this term.

Proteins are complex, large molecules that play critical roles in the body's functions. They are made up of amino acids, which are organic compounds that are the building blocks of proteins. Proteins are required for the structure, function, and regulation of the body's tissues and organs. They are essential for the growth, repair, and maintenance of body tissues, and they play a crucial role in many biological processes, including metabolism, immune response, and cellular signaling. Proteins can be classified into different types based on their structure and function, such as enzymes, hormones, antibodies, and structural proteins. They are found in various foods, especially animal-derived products like meat, dairy, and eggs, as well as plant-based sources like beans, nuts, and grains.

The term "Theoretical Models" is used in various scientific fields, including medicine, to describe a representation of a complex system or phenomenon. It is a simplified framework that explains how different components of the system interact with each other and how they contribute to the overall behavior of the system. Theoretical models are often used in medical research to understand and predict the outcomes of diseases, treatments, or public health interventions.

A theoretical model can take many forms, such as mathematical equations, computer simulations, or conceptual diagrams. It is based on a set of assumptions and hypotheses about the underlying mechanisms that drive the system. By manipulating these variables and observing the effects on the model's output, researchers can test their assumptions and generate new insights into the system's behavior.

Theoretical models are useful for medical research because they allow scientists to explore complex systems in a controlled and systematic way. They can help identify key drivers of disease or treatment outcomes, inform the design of clinical trials, and guide the development of new interventions. However, it is important to recognize that theoretical models are simplifications of reality and may not capture all the nuances and complexities of real-world systems. Therefore, they should be used in conjunction with other forms of evidence, such as experimental data and observational studies, to inform medical decision-making.

Gene expression profiling is a laboratory technique used to measure the activity (expression) of thousands of genes at once. This technique allows researchers and clinicians to identify which genes are turned on or off in a particular cell, tissue, or organism under specific conditions, such as during health, disease, development, or in response to various treatments.

The process typically involves isolating RNA from the cells or tissues of interest, converting it into complementary DNA (cDNA), and then using microarray or high-throughput sequencing technologies to determine which genes are expressed and at what levels. The resulting data can be used to identify patterns of gene expression that are associated with specific biological states or processes, providing valuable insights into the underlying molecular mechanisms of diseases and potential targets for therapeutic intervention.

In recent years, gene expression profiling has become an essential tool in various fields, including cancer research, drug discovery, and personalized medicine, where it is used to identify biomarkers of disease, predict patient outcomes, and guide treatment decisions.

Program Evaluation is a systematic and objective assessment of a healthcare program's design, implementation, and outcomes. It is a medical term used to describe the process of determining the relevance, effectiveness, and efficiency of a program in achieving its goals and objectives. Program evaluation involves collecting and analyzing data related to various aspects of the program, such as its reach, impact, cost-effectiveness, and quality. The results of program evaluation can be used to improve the design and implementation of existing programs or to inform the development of new ones. It is a critical tool for ensuring that healthcare programs are meeting the needs of their intended audiences and delivering high-quality care in an efficient and effective manner.

CDC Public Health Genomics and Precision Health Knowledge Base (PHGKB) is an online, continuously updated, searchable database ... The Knowledge Base is curated by CDC staff and is regularly updated to reflect ongoing developments in the field. This ... A knowledge base for tracking the impact of genomics on population health Genet Med.2016 Dec;18(12):1312-1314 ... We will continue to add additional features to the knowledge base and are interested in your feedback via email. ...
Knowledge Bases. Knowledge Acquisition, Capture, and Integration. *. Knowledge Refinement in a Reflective Architecture. Yolanda ... The Acquisition, Analysis and Evaluation of Imprecise Requirements for Knowledge-Based Systems. John Yen, Xiaoqing Liu, Swee ... Building Non-Brittle Knowledge-Acquisition Tools. Jay T. Runkel, William P. Birmingham ... Knowledge Bases. *. Extracting Viewpoints from Knowledge Bases. Liane Acker, Bruce Porter. 547 ...
Tags database, knowledge base, MyPHGKB, PHGKB Dealing with the Genomics and Health Information Overload: Introducing the CDC ... Public Health Genomics Knowledge Base. Understanding genetic information is increasingly becoming important for health decision ... knowledge base - Genomics and Precision Health Blog ...
A knowledge base KB is consistent iff its negation is not a tautology. I.e., a knowledge base KB is inconsistent (not ... Example of an inconsistent knowledge base: KB := { a, ¬a } Consistency in terms of knowledge bases is mostly the same as the ... v t e v t e (Knowledge representation, All stub articles, Logic stubs, Database stubs). ...
... and revise knowledge within a neurocomputing system.Neurocomputing methods are loosely base... ... Looking at ways to encode prior knowledge and to extract, refine, ... The focus of knowledge-based computing is on methods to encode prior knowledge and to extract, refine, and revise knowledge ... In knowledge-based neurocomputing, the emphasis is on the use and representation of knowledge about an application. Explicit ...
Slade Knowledge Base is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License, 2018 ... Product Knowledge, Rubber Surfaces, Sakura, Stone Masonry, Uk Importer, Walters And Walters, Welders. ...
Session 7: Roundtable: Policy Design for Knowledge-based Capital Knowledge is acclaimed as a resource in many policy contexts, ... How should intangibles fit into jurisdiction-based tax systems? *Should varieties of knowledge-based assets be exempted or ... but the breadth and complex nature of knowledge makes it difficult to deal with knowledge-based capital as a coherent policy ... The deliberations will feed into the conclusions of a wide-ranging two-year OECD project on knowledge-based capital and growth. ...
A new report from the UN Environment Programme, UNOPS and the University of Oxford highlights the contributions of nature-based ... community and beyond on the PreventionWeb knowledge. ...
Bases Fundamentales de la Biotecnología y Bioseguridad (Cursos para Profesores). 26 - 28 August 2004, Lima, Peru ...
Contribution to the Preparation for the Forthcoming International Technical Conference on the Conservation and Utilization of Plant Genetic Resources for Food and Agriculture in 1996. ...
New content is monitored and added on a daily basis. ... Find here the latest additions to the knowledge base platform ... Explore the Knowledge Base. PreventionWebs knowledge base contains more than 75,000 entries and is updated daily. ... The DRR Knowledge Base. Explore the latest on disaster risk and resilience from around the world: news, research, policies and ... The Knowledge Base is a collaborative effort of the DRR community, updated and reviewed daily by PreventionWeb editors. ...
Remote participants will have the best experience in a Teams meeting using the Teams app on a computer or mobile device. However, some situations may prevent colleagues from attending online meetings via the Teams app (lack of high-speed internet, available computing device, etc.). A Teams Audio Conference License is part of the Office 365 A3 license provisioned to current students, staff, and faculty. Any online meetings created by someone who has this license will automatically include a telephone number that can be called to join the audio portion of the meeting.. ...
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As a science-based organisation, Wetlands International constantly seeks to develop new and innovative research that can help ... We openly publish our knowledge, decision support tools and publications for the benefit of the international community, with ...
Formalizing and Compiling Background Knowledge and Its Applications to Knowledge Representation and Question Answering ... Formalizing and Compiling Background Knowledge and Its Applications to Knowledge Representation and Question Answering ... allowing a natural exchange of results and knowledge between them. ...
Liver Toxicity Knowledge Base (LTKB) Publications - Top 15 Citations from Google Scholar on Aug. 24, 2022 ... Liver Toxicity Knowledge Base (LTKB) Liver Toxicity Knowledge Base Publications - Top 15 Citations. Top 15 Citations of LTKB ... In this section: Liver Toxicity Knowledge Base (LTKB) * Liver Toxicity Knowledge Base (LTKB) *LTKB Benchmark Dataset ... Liver Toxicity Knowledge Base (LTKB) - A Systems Approach to a Complex Endpoint.. 2013. ...
... review and share the information they need in this Knowledge Base app. Maximize collaboration and knowledge sharing efforts ... Essential Support Knowledge Base Create a library of articles and frequently asked questions to allow your community to quickly ... review and share the information they need in this Knowledgebase app. Maximize collaboration and knowledge sharing efforts… ...
Internet as a knowledge base edit The next evolution for the term "knowledge-base" was the Internet. With the rise of the ... A knowledge-based system consists of a knowledge-base representing facts about the world and ways of reasoning about those ... The volume requirements were also different for a knowledge-base compared to a conventional database. The knowledge-base needed ... "knowledge-base" to describe their repositories but the meaning had a big difference. In the case of previous knowledge-based ...
Source citations and attribution for Wolfram Knowledgebase curated data, including required attribution content for third-party ... Wolfram Language Revolutionary knowledge-based programming language. Wolfram Cloud Central infrastructure for Wolframs cloud ... Knowledge-based broadly deployed natural language. Wolfram Data Framework Semantic framework for real-world data. Wolfram ... The inclusion of an item in this list does not necessarily mean that its content was used as the basis for any specific Wolfram ...
knowledge baseknowledge-based system ♦ knowledge level ♦ Knowledge Management System Try this search on Wikipedia, ... KBS) A program for extending and/or querying a knowledge base. The related term expert system is normally used to refer to a ...
A knowledge base lets you educate customers, proactively provide support, and improve customer success and understanding across ... 2. Keep your knowledge base on brand.. Your knowledge base is yet another reflection of your branding. Failing to keep your ... Developing your knowledge base is only half the battle. A remarkable knowledge base is a living document that needs to be ... 5. Share your knowledge base everywhere.. A great knowledge base isnt only accessed when needed; its also used to support ...
Investment and growth in OECD economies is increasingly driven by knowledge-based capital (KBC). Three types of KBC can be ... OECD Home Industry and entrepreneurshipGrowth, Innovation And Competitiveness: Maximising The Benefits Of Knowledge-Based ... researchers and policy analysts will examine the policy implications of growing business investment in knowledge-based capital ... business leaders will also be invited to help better understand how OECD economies can harness investments in knowledge-based ...
Evaluating the Quality of a Knowledge Base Populated from Text, InProceedings, Joint Workshop on Automatic Knowledge Base ... Joint Workshop on Automatic Knowledge Base Construction and Web-scale Knowledge Extraction, June 2012, 2783 downloads. ... T. Wolfe, M. Dredze, J. Mayfield, P. McNamee, C. Harmon, T. Finin, and B. Van Durme, Interactive Knowledge Base Population, ... M. Dredze, P. McNamee, D. Rao, A. Gerber, and T. Finin, Entity Disambiguation for Knowledge Base Population, InProceedings, ...
Hughes, J. M. (2004). The Impressive and Rapidly Expanding Knowledge Base on SARS. Emerging Infectious Diseases, 10(2), 171-172 ... The Impressive and Rapidly Expanding Knowledge Base on SARS. Emerging Infectious Diseases. 2004;10(2):171-172. doi:10.3201/ ... This diversity also illustrates the substantial contributions of many disciplines to the growing knowledge base on SARS. The ... The Impressive and Rapidly Expanding Knowledge Base on SARS On This Page ...
Organize knowledge and lighten the load of your support team with knowledge base from ServiceDesk Plus MSP. Get the free 30-day ... What is a knowledge base for MSPs?. A knowledge base (kbase) is an organized repository of relevant data, structured with IT ... Why is a knowledge base important?. Technicians commonly receive requests to log tickets from clients. Managing such requests ... For MSPs, knowledge base management includes classifying and personalizing topics for each account, setting up restrictions on ...
Knowledge Base WordPress Theme, TechDesk - Responsive Knowledge Base/FAQ Theme ... faq WordPress theme website templates on ThemeForest such as Knowledge Base , Helpdesk , Wiki , FAQ WordPress Theme, ... Knowledge. Base. and Q/A WordPress. Theme. by Fluent-Themes in Miscellaneous ... Knowledge. base. & LMS WordPress. Theme. with Forum by spider-themes in Software ...
Your degree certificate is produced based on the approved list of courses. Therefore always check your list of courses to see ... Your degree certificate (diploma) will be based on your approved list of courses. Therefore check your list of courses to see ... we work together with third parties to offer you personalized content based on your visit. ...
In this paper, we explore if and how a specific type of Linked Open Data, namely hierarchical knowledge, may be utilized for ... In this paper, we explore if and how a specific type of Linked Open Data, namely hierarchical knowledge, may be utilized for ... We propose a content-based recommendation approaches that adapts a spreading activation algorithm over the DBpedia category ... We propose a content-based recommendation approaches that adapts a spreading activation algorithm over the DBpedia category ...
Geograph Britain and Ireland is a web-based project to collect and reference geographically representative images of every ... The answers given by Barry have been on the site for a long time, and they form the basis of what the site is about. Yet many ... decisions might fall another side of the border but such decisions are initially based on their interpretation of the ...
  • One easy first step up the ladder is to build an online knowledge base, which is a centralized repository of information about how to get online, add a new app, or navigate the thousands of tech-enabled processes that are unique to each school or district. (eschoolnews.com)
  • By creating a repository of articles and FAQs in the knowledge management system , customers can find their own answers without waiting for an agent. (zoho.com)
  • MAKRS: a knowledge and belief representation system for multiple agents. (uni-trier.de)
  • His primary focus recently has been the integration of natural language processing, knowledge representation, machine learning and advanced visualization techniques to address challenges in interpreting data generated by high throughput molecular biology. (nih.gov)
  • This note describes work on the design of a Knowledge Base Server - a distributed architecture for delivering knowledge representation and reasoning services to applications. (umbc.edu)
  • Yuta Nakashima KnowIT VQA: Answering Knowledge-Based Questions about Videos Proceedings of the AAAI Conference on Artificial Intelligence, 34 (2020) 10826-10834. (aaai.org)
  • Yuta Nakashima KnowIT VQA: Answering Knowledge-Based Questions about Videos AAAI 2020, 10826-10834. (aaai.org)
  • The QIAGEN Biomedical Knowledge Base is built with manually-curated and comprehensive proprietary ontologies. (qiagen.com)
  • This paper presents some issues in visualizing and navigating biomedical ontologies and knowledge bases through case studies of two applications developed at the U.S. National Library of Medicine. (nih.gov)
  • The importance of knowledge management has been recognized both in academia and in practice. (igi-global.com)
  • Several contributions to medical practice might have arisen from anatomical knowledge emerging from human sacrifice and decapitation techniques. (medscape.com)
  • International conferences on community-based adaptation (CBA) enable practitioners, governments and donors to share latest developments and best practice. (iied.org)
  • We studied physicians' knowledge of the occurrence, frequency and causes of medical errors and their actual practice toward reporting them. (who.int)
  • The questionnaire had 6 sections covering demographic data, knowledge, attitudes and practice towards reporting medical errors, perceived causes of and frequency of medical errors in their hospital and personal experiences of medical error reporting. (who.int)
  • QIAGEN Biomedical Knowledge Base is the leading knowledge about biomedical relationships, manually structured and integrated from thousands of sources by experts. (qiagen.com)
  • The QIAGEN Biomedical Knowledge Base is intended for molecular biology applications. (qiagen.com)
  • Access the leading source of biomedical relationships knowledge to accelerate data- and analytics-driven drug discovery. (qiagen.com)
  • Use it to power biomedical knowledge graph analysis, artificial intelligence (AI)-driven target identification and many more innovative applications. (qiagen.com)
  • Learn more about QIAGEN Biomedical Knowledge Base . (qiagen.com)
  • Our integrated knowledge enables you to automatically identify and prioritize hypotheses within minutes using biomedical knowledge graph analysis, AI and more. (qiagen.com)
  • QIAGEN Biomedical Knowledge Base powers biomedical knowledge graph construction and analysis, AI-driven target identification and drug repositioning, target, disease and drug intelligence portals, as well as disease subtype and biomarker identification. (qiagen.com)
  • The primary exposure was LCS guideline knowledge (US Preventive Services Task Force/Centers for Medicare & Medicaid Services). (nih.gov)
  • Introducing a new product can lead to a steep learning curve that a knowledge base can soften. (ringcentral.com)
  • Archaeological evidence suggests that all of these practices required specialized knowledge of skull base and upper cervical anatomy. (medscape.com)
  • A detailed exposition of these results is presented, along with some interesting information extracted from historical documents and pictorial codices to provide a better understanding of skull base surgical practices among these cultures. (medscape.com)
  • PIARC (World Road Association), founded in 1909 and comprising 125 member governments from all over the world, is the global forum for exchange of knowledge and experience on roads, road transport policies and practices. (piarc.org)
  • A cross-sectional survey was performed in a large academic medical center and affiliated Veterans Health Administration in the Mid-South United States that comprises hospital and community-based practices. (nih.gov)
  • The intervention presented a variety of interactive exercises, multimedia clips, quizzes, and other materials that provided information about safer sex practices and tested participants' knowledge of HIV risk factors. (nih.gov)
  • The Firefox Knowledge Base (also known as SUMO, or support.mozilla.com) launched as alpha , with all content licensed under CC Attribution-ShareAlike . (creativecommons.org)
  • Second, we propose a video understanding model by combining the visual and textual video content with specific knowledge about the show. (aaai.org)
  • Should the knowledge content not address the issue, a quick click through the service-request catalog will create a ticket and route it to the appropriate resource. (eschoolnews.com)
  • In addition to the optimal functioning of the website, we work together with third parties to offer you personalized content based on your visit. (rug.nl)
  • Nonetheless, these 4 models are believed to be able to reflect the current level of web-based knowledge management, which can be basically described as content-based information retrieval and topic-oriented information association and organization. (igi-global.com)
  • We cut back on producing daily content - a decision based on analysis of the cost effectiveness and impact of certain activities in the previous year. (iied.org)
  • Any kind of information will look good in your Bitrix24 Knowledge Base: how-tos, articles, check-lists, documentation, or any other type of content. (bitrix24.com)
  • Anyone can create a knowledge base in Bitrix24 - just pick a template and start filling it up with articles, images, videos, or other types of content. (bitrix24.com)
  • Everyone who's participating in the project will get access to this knowledge base and can edit, share and discuss the content inside it. (bitrix24.com)
  • The content on this page is provided for historical reference purposes only and may not reflect current knowledge or information. (nih.gov)
  • But when it comes to managing 75,000 K-12 students with brand new school-issued iPads or their own devices, there is often no knowledge base or even an adequate tech-support system in place to adequately assist them. (eschoolnews.com)
  • Customize your Help Center completely for each brand you support, and set up different Knowledge Base Articles for every brand. (zoho.com)
  • Support documentation is automatically embedded into IT workflows, and agents can reference and write knowledge base articles from their service management project. (atlassian.com)
  • Meanwhile, the web technology is being used as a new and common medium to support the collective nature of knowledge management. (igi-global.com)
  • The MAPGenKB will provide logistical and informatics support for the research across all RCs in the MAPGen consortium and synthesize the knowledge from the datasets of the RCs and other sources that are relevant to the goals of the MAPGen consortium. (nih.gov)
  • I ndividuals with the skills, knowledge, and resources necessary to carry out the proposed research are invited to work with their institution/organization to develop an application for support. (nih.gov)
  • This funding opportunity announcement (FOA) offers support for a high impact pharmacogenomics knowledge base as a research resource available to the entire scientific community. (nih.gov)
  • This FOA solicits applications to maintain and enhance the PSI:Biology Knowledgebase in support of NIGMS PSI:Biology projects. (nih.gov)
  • To brainstorm ideas for your knowledge base articles, talk to your customer support team to find out what questions are coming up most often. (hubspot.com)
  • Once you've tackled writing articles from a support perspective, if you have an implementation team, ask them what their most successful customers do in the first 30 days and write knowledge base articles in reference to on-boarding. (hubspot.com)
  • The Knowledge Base contains numerous support references, created by our support professionals who have resolved issues for our customers. (nih.gov)
  • Lifelong learning allows us to continuously expand our knowledge base, adapt to new challenges, and enhance personal fulfillment. (johnnyholland.org)
  • As you continue on this lifelong learning journey, remember that growth doesn't stop at acquiring new knowledge - it also involves continuous improvement and keeping skills current. (johnnyholland.org)
  • Machine-readable knowledge bases store data that can only be analyzed by artificial intelligence systems. (hubspot.com)
  • The goals of the conference are to evaluate the efficacy and safety of vitamin D, identify gaps in knowledge on the efficacy and safety of vitamin D, inform NIH and other Federal agencies on vitamin D and health research priorities, and to disseminate the conference findings to the broad scientific nutrition community. (nih.gov)
  • Strategies to advance evidence-based LCS should incorporate provider education and system-level interventions to address gaps in provider knowledge. (nih.gov)
  • Having extensive and relevant knowledge base tools providing those answers is crucial to providing and maintaining a better customer experience. (ringcentral.com)
  • As a hub for all of your important information, knowledge bases are crucial for the success of your business. (callcentrehelper.com)
  • Developing energy skills and knowledge is crucial for Africa's long-term economic and sustainable development, said the World Energy Council on 3 September at a workshop on energy statistics skills training and capacity building, organised by the African Energy Commission (AFREC). (worldenergy.org)
  • Explore DRR on a country and regional basis. (preventionweb.net)
  • Explore and analyze integrated knowledge about causal relationships that are enriched with full context between genes, diseases, drugs, targets, functions, toxicological processes and more to produce novel discoveries otherwise hidden among siloed and diverse data. (qiagen.com)
  • Whether you want to enhance your career prospects, explore new hobbies, or simply satisfy your thirst for knowledge, lifelong learning is the key that unlocks endless possibilities. (johnnyholland.org)
  • Let's go over some key reasons why knowledge bases are important. (hubspot.com)
  • A good knowledge base is important for your staff to provide that reference point and act as a teaching and learning tool. (ringcentral.com)
  • A knowledge base is important to your organisation. (ringcentral.com)
  • Create a knowledge base with its own rules, algorithms, and other important information inside a workgroup. (bitrix24.com)
  • The knowledge base has been an important contributor of highly curated, trustworthy information for the field. (nih.gov)
  • In addition, it has catalyzed the formation of very successful important community-driven activities based upon pharmacogenomics knowledge, such as the Clinical Implementation Pharmacogenetics Consortium ( CPIC ) and the Drug-specific Consortia in Pharmacogenomics (e.g. (nih.gov)
  • In a fast-paced and ever-evolving society, expanding your knowledge base has become more important than ever before. (johnnyholland.org)
  • Internet-based delivery also allows high-risk individuals to access the intervention privately, at their convenience, and possibly at important "teaching opportunities," such as when they are actively seeking new partners online. (nih.gov)
  • January 2017 Thanks to its diversified resources and high growth potential, the African continent is called to address its huge development challenges by STI and to take advantage of the raise of the knowledge based Economy (KBE) to have a bigger weight in the global economy. (slideshare.net)
  • In D. White (Ed.), Knowledge Mapping and Management (pp. 131-143). (igi-global.com)
  • A knowledge base doesn't simply have to be a reservoir of help center articles. (hubspot.com)
  • It pulls up relevant articles from the KB based on keywords in the ticket. (zoho.com)
  • However, agent productivity can be further streamlined by providing employees with immediate access to knowledge base articles right from an issue or request. (atlassian.com)
  • Our knowledge base has hundreds of articles that answer common questions a user might run into while using HubSpot products. (hubspot.com)
  • We'll walk through these tips and tricks by dissecting one of HubSpot's own knowledge base articles . (hubspot.com)
  • Example of an inconsistent knowledge base: KB := { a, ¬a } Consistency in terms of knowledge bases is mostly the same as the natural understanding of consistency. (wikipedia.org)
  • We propose a novel video understanding task by fusing knowledge-based and video question answering. (aaai.org)
  • Transitioning or blending should be done by a roofing contractor based on the architectural style of the roof. (airvent.com)
  • During the centuries following the establishment of the first agricultural settlements, several common social and cultural features evolved among Mesoamerican societies, such as complex calendar and numeral systems, rich and colorful mythological traditions, advanced astronomical knowledge, and a distinct architectural style, whose vestiges still remain. (medscape.com)
  • Offer a wealth of information at your customers' fingertips-along with features like smart search, knowledge reports and scoring, template suggestions, etc.-by leveraging the power of Confluence and Jira Service Management . (atlassian.com)
  • The beauty of the Bitrix24 Knowledge Base is in its simplicity and template-based approach. (bitrix24.com)
  • The findings show that Internet-based interventions can affect HIV risk behavior. (nih.gov)
  • And without a knowledge base, your employees could waste even more time searching for the answers in emails and other databases. (ringcentral.com)
  • is simple: knowledge bases are like databases and their services should be provided in a similar manner - in a client-server relationship. (umbc.edu)
  • The knowledge base is a place for your team to organize all customer-facing (or employee-facing) FAQs and documentation. (atlassian.com)
  • A single place for you to store all your corporate knowledge and wisdom, Bitrix24 Knowledge Base can be easily edited and expanded by all your team members. (bitrix24.com)
  • Contact our KnowledgeBase Admin team at [email protected] . (wisc.edu)
  • The National Heart, Lung, and Blood Institute (NHLBI) encourages grant applications under this Funding Opportunity Announcement (FOA) to develop and implement a Knowledge Base (KB) and Coordinating Center for the Consortium of Cross Organ Mechanism-Associated Phenotypes for Genetic Analyses of Heart, Lung, Blood, and Sleep Diseases (MAPGen for HLBS). (nih.gov)
  • The visualization of complex and extensive knowledge structures poses specific challenges, namely to represent enough significant information while limiting the cognitive load. (nih.gov)
  • A promising solution to fill this gap is to develop an intelligent genetic test recommendation system that not only can provide a comprehensive view of genetic tests as education resources, but also can recommend the most appropriate genetic tests to patients based on clinical evidence. (nih.gov)
  • In this study, we developed an EHR based Genetic Testing Knowledge Base for Individualized Medicine (iGTKB). (nih.gov)
  • A knowledge base is a collection of information that answers a range of common questions likely to be asked. (ringcentral.com)
  • Making this clear is the common basis for success in China. (hannovermesse.de)
  • Below are some of the most common knowledge base issues, because we understand that the struggle is real. (callcentrehelper.com)
  • Onboard and train new employees by allowing them to search for the most common questions in your knowledge base. (bitrix24.com)
  • One of the most common forms of self-service that an organization can offer is a knowledge base. (hubspot.com)
  • In a knowledge base article, the title serves multiple purposes. (hubspot.com)
  • The Knowledgebase will be one component of the PSI:Biology network. (nih.gov)
  • Knowledge bases may seem simple, but let's step back and put the idea in context. (hubspot.com)
  • [ 10 ] In the context of a world of perpetual war among tribes and hand-to-hand combat, [ 3 ] considerable surgical applications might have emerged from this anatomical knowledge, such as the use of gold and silver to perform cranioplasties, refined surgical techniques to treat combat wounds, and the development of head protection devices. (medscape.com)
  • Our main findings are: (i) the incorporation of knowledge produces outstanding improvements for VQA in video, and (ii) the performance on KnowIT VQA still lags well behind human accuracy, indicating its usefulness for studying current video modelling limitations. (aaai.org)
  • Now that you have a basis of what to write about, let's dive into the article, starting from the top: the title. (hubspot.com)
  • All knowledge bases share valuable information with customers and prospects, but the type of data and information you include in it depends on your business' purpose for creating one. (hubspot.com)
  • ProcedureFlow share some all-too-familiar knowledge base frustrations and how to overcome them. (callcentrehelper.com)
  • Under the leadership of WHO, members of normally competitive groups worked together, often communicating several times a day, to acquire and share knowledge to stop the spread of disease. (cdc.gov)
  • What type of data is included in a knowledge base? (hubspot.com)
  • Knowledge-based clustering approach for data abstraction. (uni-trier.de)
  • Integration of scientific data and formulae in an object-oriented knowledge-based system. (uni-trier.de)
  • This chapter provides an overview and general guidelines on the potential use of new data and computational methods to enhance tourism's knowledge base, encourage their institutional adoption and, ultimately, foster a more sustainable tourism. (springer.com)
  • Research was carried out in order to develop a database of protein knowledge containing structure and sequence information and extend the database to include information on inferred 3-dimensional structures of proteins for which only sequence data are available. (europa.eu)
  • Based on the combined data of two trials, the decreased risk of fractures was seen primarily in the subgroup of elderly women (average age 85 years) living in nursing homes. (nih.gov)
  • A knowledge base helps them deal with customer inquiries quickly and efficiently without seeking another employee to answer a query. (ringcentral.com)
  • These techniques are used by various UMLS-based applications, including SemNav. (nih.gov)
  • There are two main forms of knowledge bases: machine-readable and human-readable. (hubspot.com)
  • In today's rapidly changing world, the knowledge and skills we acquire may become obsolete sooner than we expect. (johnnyholland.org)
  • 8 2.4 The Healthcare sector as a knowledge based industry. (slideshare.net)
  • The answers given by Barry have been on the site for a long time, and they form the basis of what the site is about. (geograph.org.uk)
  • It would be a misconception to hope that high technology could be sold to innovative customers and at the same time encapsulate one's knowledge from the markets even today. (hannovermesse.de)
  • Your knowledge base can't read your mind, and having to take time out of work to pull up the necessary article feels slow and archaic. (callcentrehelper.com)
  • When customers would rather search their questions and get an immediate solution than pick up the phone, you need to speak to their desire, and the best way to do so is through a knowledge base . (hubspot.com)
  • A knowledge base is a self-serve customer service library that includes information about a product, service, or topic that helps customers find answers so they can solve problems on their own. (hubspot.com)
  • By providing a helpful knowledge base, your customers can get the answers they need on their own. (hubspot.com)
  • Many of our customers have seen a 50- to 70-percent drop in call volume by implementing a knowledge base and portal in their school or district. (eschoolnews.com)
  • Your knowledge base may be stored on your systems where staff can access the information or publish it on your website or portals where customers can easily access it. (ringcentral.com)
  • Knowledge Base Software for faster answers, fewer tickets, and happier customers. (zoho.com)
  • Setting your company up with a knowledge management solution that understands your struggles, and is designed specifically with you in mind, can make a world of difference in not only your employees' lives, but the satisfaction of your customers as well. (callcentrehelper.com)
  • You can also create an internal knowledge base , where you provide helpful information to your employees, like benefits information, company holidays, etc. (hubspot.com)
  • Whether you have an existing knowledge base or you're about to create your first, the process of building a library of self-serve knowledge is rather intuitive. (atlassian.com)
  • Create a knowledge base space in Confluence and link it to your service desk right from Jira Service Management. (atlassian.com)
  • You can create a separate chat for every knowledge base to discuss various matters related to it. (bitrix24.com)
  • Diagnostic expert system inference engine based on the certainty factors model. (uni-trier.de)
  • Feasibility study and impact assessment for a knowledge-based information-technology planning system. (uni-trier.de)
  • "Establishing and implementing comprehensive energy information systems and database is critical for energy system planning, long-term investment plans, sound energy policies and sustainable development," said Dr Latsoucabé Fall, WEC Regional Manager for Africa and a proponent of boosting Africa's energy skills base. (worldenergy.org)
  • I.e., a knowledge base KB is inconsistent (not consistent) iff there is no interpretation which entails KB. (wikipedia.org)
  • Do we expect them to retain large amounts of knowledge across a range of topics? (ringcentral.com)
  • Human-readable knowledge bases store documents and physical texts that humans can access. (hubspot.com)
  • You can restrict access to certain information by configuring permission settings - for a specific knowledge base or for all of them at once. (bitrix24.com)
  • You can access your Bitrix24 Knowledge Base from any device and any place - whether you're in the office, at home, or on the road. (bitrix24.com)
  • For example, the Knowledge Base article on managing the Firefox search bar , which includes CC Search in its default list of available search engines. (creativecommons.org)
  • If you haven't yet added Confluence to your service management solution, you can choose which Confluence plan (free, standard, premium, enterprise) to add to your site based on your knowledge base needs. (atlassian.com)
  • Web-Based Knowledge Management. (igi-global.com)
  • In this chapter, 4 types of web-based knowledge management models are identified and discussed. (igi-global.com)
  • This chapter concludes that the current web-based knowledge management is at a lower level, and, the potential of the web technology based knowledge management has just started to be realized. (igi-global.com)
  • However, knowledge management does not have to be so difficult. (callcentrehelper.com)
  • The importance of an easy-to-use knowledge management tool has never been more apparent. (callcentrehelper.com)
  • People come and go, but knowledge must stay inside your company. (bitrix24.com)
  • The basis of our positioning in Japan was connection technology, which Japanese companies need for the international market. (hannovermesse.de)
  • Development of a generalized knowledge source structure for blackboard systems. (uni-trier.de)
  • Evidence-based information for guiding the development of workplace health promotion programs is particularly lacking in Western Australia, the state with the highest prevalence (63%) of overweight/obesity in Australia (10). (cdc.gov)
  • We show that these two approaches are equivalent for propositional knowledge base updates, and the second method is also appropriate for first order knowledge base updates. (aaai.org)

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