Effect of prolonged thiazide treatment on renal lithium clearance. (1/2)
Renal lithium clearances were determined after the administration of a small test dose of lithium carbonate in 22 patients when they were on long-term treatment with thiazides and when they were not on such treatment. Thiazide administration led to a 24% reduction in the lithium clearance. Diuretic drugs should be used with caution in patients given lithium treatment, and lithium should be used with caution in patients receiving diuretic treatment. (+info)Treatment of benign intracranial hypertension by dehydrating agents with particular reference to the measurement of the blind spot area as a means of recording improvement. (2/2)
A series of 30 patients (28 females : 2 males) presenting with benign intracranial hypertension is reported. It is shown that the papilloedema may be resolved in as little as six weeks by the use of dehydration therapy. Evidence is presented that this method can restore to normal a visual acuity which is as low as 6/24 or even 6/36. It is concluded that surgery is never required in the management of this condition. It is strongly recommended that serial blind-spot measurements should be used routinely to assess the effectiveness of therapy. Fluorescein angiography has a place in diagnosis among a small proportion of these patients. (+info)Hydroflumethiazide is a diuretic medication, which means it helps the body get rid of excess salt and water by increasing urine production. It is a type of thiazide diuretic, which works by preventing your body from absorbing too much salt and allowing it to be passed out in your urine.
Here's the medical definition:
Hydroflumethiazide is a synthetic sulfonamide-based diuretic with a thiazide-like action, chemically designated as 6-chloro-3-(2E)-2-[2,3-dihydro-1(4H)-fluorobenzothiazin-1-ylidene]ethylideneamino-5-(trifluoromethyl)pyrimidin-4-one. It has a potent natriuretic and diuretic effect by inhibiting the reabsorption of sodium and chloride ions in the distal convoluted tubule of the nephron, thereby increasing water excretion and reducing blood volume and pressure. Hydroflumethiazide is used in the management of hypertension and edema associated with congestive heart failure, cirrhosis, and renal disease.