*  Arthritis Research & Therapy | Full text | Expression of tumor necrosis factor-like weak inducer of
arthritis research therapy full text expression of tumor necrosis factor like weak inducer of apoptosis and fibroblast growth factor inducible in patients with polymyositis and dermatomyositis arthritis research com article ar bottom top biomed central journals gateways search this journal biomed central for go advanced search home articles authors reviewers about this journal my arthritis research therapy top abstract introduction methods results discussion conclusions abbreviations competing interests authors contributions acknowledgements references arthritis research therapy volume issue viewing options abstract full text pdf mb associated material pubmed record article metrics open badges readers comments related literature cited by google blog search other articles by authors on google scholar peng ql shu xm tian xl lu x wang gc on pubmed peng ql shu xm tian xl lu x wang gc related articles pages on google on google scholar on pubmed tools download references download xml order reprints post a comment d...
http://arthritis-research.com/content/16/1/R26
*  Fn14 (Fibroblast Growth Factor Inducible 14, TWEAK Receptor) antibody (ABIN1002330)
Fn14 Fibroblast Growth Factor Inducible 14, TWEAK Receptor antibody ABIN1002330. Shipping to United States. Comparison list. No Products on your Comparison List. Antibodies. ELISA Kits. Secondary Antibodies. Antibodies Primary antibodies Secondary antibodies Kits ELISA Kits Assay Kits Reagents Protein Peptide Lysate Isotype Control Accessory Reagent Suppliers Pathways. Antibodies Primary antibodies Secondary antibodies Kits ELISA Kits Assay Kits Reagents Protein Peptide Lysate Isotype Control Accessory Reagent Suppliers Pathways. Comparison list. Shipping to United States. Search, Find and Buy Antibodies, ELISA Kits and Proteins. Antibodies. Secondary Antibodies. Kits. ELISA Kits. Antibodies. anti-Fn14 Fibroblast Growth Factor Inducible 14, TWEAK Receptor antibody. Fn14 Fibroblast Growth Factor Inducible 14, TWEAK Receptor antibody. Details for Product No. Fn14 Fibroblast Growth Factor Inducible 14, TWEAK Receptor. Application. 4 references available. Product details. References. Handling. Application Details...
http://antibodies-online.com/antibody/1002330/anti-Fn14 Fibroblast Growth Factor Inducible 14 TWEAK Receptor/
*  www.arthritis-research.com - Table
www arthritis research com table table correlations between scd stweak and scd stweak ratio and clinical and laboratory parameters of patients with systemic sclerosis parameter number of subjects r spearman p value scd stweak scd stweak disease duration p p p duration of raynaud s phenomenon p p p mrss p p p fvc p p p dlco p p p pasp p p p esr p p p stweak soluble tumour necrosis factor like weak inducer of apoptosis dlco diffusing capacity of the lungs for carbon monoxide esr erythrocyte sedimentation rate fvc forced vital capacity mrss modified rodnan skin score pasp pulmonary artery systolic pressure kowal bielecka et al arthritis research therapy r doi ar...
http://arthritis-research.com/content/15/3/R69/table/T3
*  “Pimp My ROM” script makes its way to rooted users for easy access to tweaks and hacks | TalkAnd
Pimp My ROM script makes its way to rooted users for easy access to tweaks and hacks. TalkAndroid.com. TalkAndroid. TalkAndroid. Privacy Policy. Get the TalkAndroid App. Pimp My ROM script makes its way to rooted users for easy access to tweaks and hacks Macky Evangelista October 5, 2012. hack pimp my rom ROM Root XDA. With a name like Pimp My ROM, how can one not give it a try. Faster internet browsing Better Battery consumption Miscellanous kernel tweaks Ondemand governor tweaks Dalvik VM tweaks Defragmentation of sqlite3 databases at each boot Disable android-logger Disable kernel Normalize Sleeper Use strict minfree handlers Flags blocks as non-rotational Enable data writeback for ext4 partitions for better i/o Force GPU rendering on 2D operations Improve multitasking by tweaking system task-killer run Vacuum Reindex at each boot to optimize sqlite Use Adblock hosts to block in-app advertising Improve External sdcard I/O performances Zipalign all apk at each boot Install Thunderbolt s s98system tweaks Twe...
http://talkandroid.com/135227-pimp-my-rom-script-makes-its-way-to-rooted-users-for-easy-access-to-tweaks-and-hacks/
*  How Can I Tweak My Alfa 1000mW WIFI Card
... BackTrack Linux - Penetration Testing Distribution. COMMUNITY. FORUMS. BT Swag. Forum. Forum Home. Mark Forums Read. Forum. BackTrack 4 Forums. Beginners Forum. How Can I Tweak My Alfa 1000mW WIFI Card. Thread: How Can I Tweak My Alfa 1000mW WIFI Card. View Forum Posts. Just burned his ISO. Join Date Mar 2011 Posts 1. How Can I Tweak My Alfa 1000mW WIFI Card. It's suppose to run at 1000mW but when I first installed the software it had two choices one for 1 mW another one for the european 100mW setting. How can I find out if it's running at 1000mW and if not how can I tweak it to get the full potential out of this card i'm running xp pro. View Forum Posts. Good friend of the forums. Join Date Feb 2010 Location Paris, France Posts 338. Re: How Can I Tweak My Alfa 1000mW WIFI Card Hi, You can do it by setting you regulatory file to another region which I won't tell you since it's easy to find both on google and those forums. You do not have to install anything on Backtrack, driver rtl8187 does a great job a...
http://backtrack-linux.org/forums/showthread.php?t=38942&p=192385&viewfull=1
*  TNFRSF1B - Tumor necrosis factor receptor superfamily member 1B - human protein
... Proteomics. TNFRSF1B - Tumor necrosis factor receptor superfamily member 1B - human protein Proteomics. Login or Sign up now. Oooops, an error occured. TNFRSF1B - Tumor necrosis factor receptor superfamily member 1B - human protein Proteomics. Downloads Login or Sign up. Login Or Sign up Now. Protein. Sequence. Proteomics. Identifiers. Gene. Identifiers. TNFRSF1B Tumor necrosis factor receptor superfamily member 1B. Login or Sign up now. x Protein also known as:. Tumor necrosis factor receptor type II TNFR-II ; CD antigen CD120b; International Nonproprietary Name Etanercept. Cleaved into:. Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2. Gene name: TNFRSF1B Entry whose protein s existence is based on evidence at protein level. Protein Recommended name Tumor necrosis factor receptor superfamily member 1B. Alternative names Tumor necrosis factor receptor 2 Short : TNF-R2. Tumor necrosis factor receptor type II Short : TNFR-II, TNF-RII. p80 TNF-al...
http://nextprot.org/db/entry/NX_P20333/proteomics
*  NM 001066 TaqMan SNP Genotyping Assays
C 166922933 10 details, C 166922933 10 search Human tumor necrosis factor receptor superfamily, member 1B CD120b;TBPII;TNF-R-II;TNF-R75;TNFBR;TNFR1B;TNFR2;TNFR80;p75;p75TNFR NM 001066.2 rs149512902. C 8861229 10 details, C 8861229 10 search Human tumor necrosis factor receptor superfamily, member 1B CD120b;TBPII;TNF-R-II;TNF-R75;TNFBR;TNFR1B;TNFR2;TNFR80;p75;p75TNFR NM 001066.2 rs1061624. C 30915044 10 details, C 30915044 10 search Human tumor necrosis factor receptor superfamily, member 1B CD120b;TBPII;TNF-R-II;TNF-R75;TNFBR;TNFR1B;TNFR2;TNFR80;p75;p75TNFR NM 001066.2 rs12062134. C 30915071 10 details, C 30915071 10 search Human tumor necrosis factor receptor superfamily, member 1B CD120b;TBPII;TNF-R-II;TNF-R75;TNFBR;TNFR1B;TNFR2;TNFR80;p75;p75TNFR NM 001066.2 rs5745981. C 30915125 10 details, C 30915125 10 search Human tumor necrosis factor receptor superfamily, member 1B CD120b;TBPII;TNF-R-II;TNF-R75;TNFBR;TNFR1B;TNFR2;TNFR80;p75;p75TNFR NM 001066.2 rs5746040. C 956664 10 details, C 956664 ...
https://thermofisher.com/order/genome-database/browse/genotyping/keyword/NM_001066?CID=AF_NCBI_NUCLEOTIDE
*  MLS000702159(CID 56642938) - Compound BioActivity Data
SID 22401928. Outcome Active. AID 588342. PubMed. Data Table. SID 22401928. Outcome Active. AID 1814. BioAssay type screening. PubMed. Data Table. A qHTS for Small Molecule Inhibitors of Shiga Toxin shiga toxin 1 variant A subunit View X Row No. Outcome Active. BioAssay type screening. Data Table. Outcome Active. BioAssay type screening. PubMed. Data Table. Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin shiga toxin 1 B subunit View X Row No. Outcome Active. BioAssay type screening. Data Table. A qHTS for Small Molecule Inhibitors of Shiga Toxin shiga toxin 1 B subunit View X Row No. Target tumor necrosis factor receptor superfamily member 10B isoform 1 precursor. Single concentration confirmation of Caspase-8 TRAIL sensitizer hits in a luminesence panel assay tumor necrosis factor receptor superfamily member 10B isoform 1 precursor View X Row No. Target tumor necrosis factor receptor superfamily member 10B isoform 1 precursor. Single concentration confirmation of Caspase-8 TRAIL sens...
http://pubchem.ncbi.nlm.nih.gov/assay/assay.cgi?cid=56642938
*  Rabbit anti-Human TNFRSF17 antibody (ABIN150438)
Rabbit anti-Human TNFRSF17 antibody ABIN150438. No Products on your Comparison List. ELISA Kits. Antibodies Primary antibodies Secondary antibodies Kits ELISA Kits Assay Kits Reagents Protein Peptide Lysate Isotype Control Accessory Reagent Suppliers Pathways. Antibodies Primary antibodies Secondary antibodies Kits ELISA Kits Assay Kits Reagents Protein Peptide Lysate Isotype Control Accessory Reagent Suppliers Pathways. ELISA Kits. anti-Tumor Necrosis Factor Receptor Superfamily, Member 17 TNFRSF17 antibody. Tumor Necrosis Factor Receptor Superfamily, Member 17 TNFRSF17 antibody. Details for Product No. Tumor Necrosis Factor Receptor Superfamily, Member 17 TNFRSF17. Application. Western Blotting WB 72, ELISA 46, Immunohistochemistry IHC 16, Flow Cytometry FACS 15, Immunohistochemistry Paraffin-embedded Sections IHC p 11, Immunofluorescence Paraffin-embedded Sections IF p 10, Immunoprecipitation IP 7, Immunocytochemistry ICC 5, Immunofluorescence IF 5, Enzyme Immunoassay EIA 3, FLISA 3, Immunoassay IA 3, Immu...
http://antibodies-online.com/antibody/150438/anti-Tumor Necrosis Factor Receptor Superfamily Member 17 TNFRSF17/
*  Tumor necrosis factor receptor 2
tumor necrosis factor receptor tumor necrosis factor receptor tumor necrosis factor receptor tnfr also known as tumor necrosis factor receptor superfamily member b tnfrsf b and cd b is a membrane receptor that binds tumor necrosis factor alpha tnfα function interactions references further reading external links function the protein encoded by this gene is a member of the tumor necrosis factor receptor superfamily which also contains tnfrsf a this protein and tnf receptor form a heterocomplex that mediates the recruitment of two anti apoptotic proteins c iap and c iap which possess e ubiquitin ligase activity the function of iaps in tnf receptor signalling is unknown however c iap is thought to potentiate tnf induced apoptosis by the ubiquitination and degradation of tnf receptor associated factor traf which mediates anti apoptotic signals knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways interactions tnfrsf b has been shown ...
https://en.wikipedia.org/wiki/Tumor_necrosis_factor_receptor_2
*  Tnfrsf1b (tumor necrosis factor receptor superfamily, member 1b) - Rat Genome Database
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b - Rat Genome Database. Gene: Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b Rattus norvegicus. Name: tumor necrosis factor receptor superfamily, member 1b. Description: ENCODES a protein that exhibits tumor necrosis factor-activated receptor activity; ubiquitin protein ligase binding ortholog ; INVOLVED IN aging; cellular response to growth factor stimulus; immune response; PARTICIPATES IN tumor necrosis factor mediated signaling pathway; amyotrophic lateral sclerosis disease pathway; cytokine mediated signaling pathway; ASSOCIATED WITH Arthritis, Experimental; Crohn Disease; Hyperalgesia; FOUND IN axon; membrane; neuronal cell body; INTERACTS WITH 1,1,1-Trichloro-2- o-chlorophenyl -2- p-chlorophenyl ethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine. MGI. Rat Cytogenetic Map 5 q36. RGSC Genome Assembly v5.0 5 166,815,372 - 166,845,910 - NCBI. RGSC Genome Assembly v3.4 5 163,666,541 - 163,697,484 - NCBI. Rat Celera...
http://rgd.mcw.edu/rgdweb/report/gene/main.html?id=621238
*  Tnfrsf1b (tumor necrosis factor receptor superfamily, member 1b) - Rat Genome Database
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b - Rat Genome Database. Gene: Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b Rattus norvegicus. Name: tumor necrosis factor receptor superfamily, member 1b. Description: ENCODES a protein that exhibits tumor necrosis factor-activated receptor activity; ubiquitin protein ligase binding ortholog ; INVOLVED IN aging; cellular response to growth factor stimulus; immune response; PARTICIPATES IN tumor necrosis factor mediated signaling pathway; amyotrophic lateral sclerosis disease pathway; cytokine mediated signaling pathway; ASSOCIATED WITH Arthritis, Experimental; Crohn Disease; Hyperalgesia; FOUND IN axon; membrane; neuronal cell body; INTERACTS WITH 1,1,1-Trichloro-2- o-chlorophenyl -2- p-chlorophenyl ethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine. MGI. Rat Cytogenetic Map 5 q36. RGSC Genome Assembly v5.0 5 166,815,372 - 166,845,910 - NCBI. RGSC Genome Assembly v3.4 5 163,666,541 - 163,697,484 - NCBI. Rat Celera...
http://rgd.mcw.edu/rgdweb/report/gene/main.html?id=RGD:621238
*  Tumor necrosis factor receptor superfamily member 1A
tumor necrosis factor receptor superfamily member a tumor necrosis factor receptor superfamily member a redirect cd...
https://en.wikipedia.org/wiki/Tumor_necrosis_factor_receptor_superfamily_member_1A
*  The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis
... Hindawi Publishing Corporation. Home. Journals. About Us. BioMed Research International. Impact Factor 1.579. About this Journal. Submit a Manuscript. Table of Contents Journal Menu. About this Journal ·. Abstracting and Indexing ·. Advance Access ·. Aims and Scope ·. Annual Issues ·. Article Processing Charges ·. Articles in Press ·. Author Guidelines ·. Bibliographic Information ·. Citations to this Journal ·. Contact Information ·. Editorial Board ·. Editorial Workflow ·. Free eTOC Alerts ·. Publication Ethics ·. Reviewers Acknowledgment ·. Submit a Manuscript ·. Subscription Information ·. Table of Contents. Open Special Issues ·. Published Special Issues ·. Special Issue Guidelines. Abstract. Full-Text PDF. Full-Text HTML. Full-Text ePUB. Full-Text XML. Linked References. Citations to this Article. How to Cite this Article. Journal of Biomedicine and Biotechnology Volume 2012 2012, Article ID 464532, ...
http://hindawi.com/journals/bmri/2012/464532/cta/
*  Tumor necrosis factor receptor 1
... 'Tumor necrosis factor receptor 1' 'TNFR1', also known as 'tumor necrosis factor receptor superfamily member 1A' 'TNFRSF1A' and 'CD120a', is a ubiquitous membrane receptor that binds tumor necrosis factor-alpha TNFα. 1 2. 3. Function Clinical significance Interactions See also References Further reading External links. Function. The protein encoded by this gene is a member of the tumor necrosis factor receptor superfamily, which also contains TNFRSF1B. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 BAG4/SODD and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. 4 Clinical significance. Germline mutations of the extracellular domains of this receptor were found to be associated with the hu...
https://en.wikipedia.org/wiki/Tumor_necrosis_factor_receptor_1
*  Tumor necrosis factor receptor family
... redirect tumor necrosis factor receptor...
https://en.wikipedia.org/wiki/Tumor_necrosis_factor_receptor_family
*  TNFRSF11B (tumor necrosis factor receptor superfamily, member 11b)
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b. Atlas of Genetics and Cytogenetics in Oncology and Haematology Home Genes Leukemias Solid Tumours Cancer-Prone Deep Insight Case Reports Journals Portal Teaching. X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA. TNFRSF11B tumor necrosis factor receptor superfamily, member 11b. Identity. Other names OCIF. OPG. TR1. HGNC Hugo TNFRSF11B. LocusID NCBI. 4982. Atlas Id 42610. Location 8q24.12. Location base pair Starts at 119935796 and ends at 119964383 bp from pter according to hg19-Feb 2009. DNA/RNA. Organization of the human OPG gene. Description START: 120,004,977 BP from PTER END: 120,033,492 BP from PTER SIZE: 28,516 bases ORIENTATION: Minus strand REFSEQ GENOMIC ASSEMBLIES: NC-000008.9 NT-008046.15 Transcription 5 exons; cDNA SIZE 2354 BP NM-002546 ; CDS: 1206 nt. Pseudogene No known pseudogenes. Protein. Note RefSeq NP-002537.3; Size: 401 amino acids; 46040 Da; Subunit: Homodimer; Subcellular location: Secreted. Osteoprotegeri...
http://atlasgeneticsoncology.org/Genes/TNFRSF11BID42610ch8q24.html
*  Rabbit anti-Human TNFRSF21 antibody (ABIN123338)
Rabbit anti-Human TNFRSF21 antibody ABIN123338. ELISA Kits. Secondary Antibodies. Antibodies Primary antibodies Secondary antibodies Kits ELISA Kits Assay Kits Reagents Protein Peptide Lysate Isotype Control Accessory Reagent Suppliers Pathways. Antibodies Primary antibodies Secondary antibodies Kits ELISA Kits Assay Kits Reagents Protein Peptide Lysate Isotype Control Accessory Reagent Suppliers Pathways. Search, Find and Buy Antibodies, ELISA Kits and Proteins. Secondary Antibodies. Kits. ELISA Kits. anti-Tumor Necrosis Factor Receptor Superfamily, Member 21 TNFRSF21 AA 371-655 ... Tumor Necrosis Factor Receptor Superfamily, Member 21 TNFRSF21 AA 371-655 antibody. Details for Product No. Tumor Necrosis Factor Receptor Superfamily, Member 21 TNFRSF21. Alternatives AA 371-655. AA 42-335 25, AA 42-56 16, Internal Region 16, AA 355-385 15, N-Term 6, AA 420-568 5, full length 5, AA 406-605 4, Extracellular Domain 3, AA 1-125 2, AA 1-349 2, AA 1-655 2, AA 371-655 2, AA 1-350 1, AA 370-655 1, AA 372-665 1, C-Term ...
http://antibodies-online.com/antibody/123338/anti-Tumor Necrosis Factor Receptor Superfamily Member 21 TNFRSF21 AA 371-655/
*  TNFRSF1B Gene - GeneCards | TNR1B Protein | TNR1B Antibody
TNFRSF1B Gene - GeneCards. TNR1B Protein. TNR1B Antibody. Free for academic non-profit institutions. Other users need a Commercial license. Keywords. Keywords. Symbols. Symbols/Aliases. Symbols/Aliases/Identifiers. Advanced. Home. User Guide. Analysis Tools. GeneAnalytics. VarElect. GeneAlaCart. GenesLikeMe. News And Views. About. Our Publications. Weizmann Institute. LifeMap Sciences Inc. Academic License Agreement. GeneCards Team. Log In /. Sign Up. My Genes. . GCID:. GC01P012167. GIFtS:. 65. TNFRSF1B. Gene Protein Coding Tumor Necrosis Factor Receptor Superfamily, Member 1B. Research Products for TNFRSF1B Gene Antibodies. Proteins. More... Animal Models. Assays. Clones. Epigenetics. In Situ Assays. miRNA. PCR Array. Proteins. CRISPR. Antibodies. Cell Lines. Compounds. Flow Cytometry. Inhib. RNA. Primers PCR Panel. Regul. Elements. Show less... Jump to section Aliases. Compounds. Disorders. Domains. Expression. Function. Genomics. Localization. Orthologs. Paralogs. Pathways. Products. Proteins. Publications...
http://genecards.org/cgi-bin/carddisp.pl?gene=TNFRSF1B&go_proc=7&rf=/home/genecards/current/website/carddisp.pl
*  TNFRSF1B Gene - GeneCards | TNR1B Protein | TNR1B Antibody
TNFRSF1B Gene - GeneCards. TNR1B Protein. TNR1B Antibody. Free for academic non-profit institutions. Other users need a Commercial license. Keywords. Keywords. Symbols. Symbols/Aliases. Symbols/Aliases/Identifiers. Advanced. Home. User Guide. Analysis Tools. GeneAnalytics. VarElect. GeneAlaCart. GenesLikeMe. News And Views. About. Our Publications. Weizmann Institute. LifeMap Sciences Inc. Academic License Agreement. GeneCards Team. Log In /. Sign Up. My Genes. . GCID:. GC01P012167. GIFtS:. 65. TNFRSF1B. Gene Protein Coding Tumor Necrosis Factor Receptor Superfamily, Member 1B. Research Products for TNFRSF1B Gene Antibodies. Proteins. More... Animal Models. Assays. Clones. Epigenetics. In Situ Assays. miRNA. PCR Array. Proteins. CRISPR. Antibodies. Cell Lines. Compounds. Flow Cytometry. Inhib. RNA. Primers PCR Panel. Regul. Elements. Show less... Jump to section Aliases. Compounds. Disorders. Domains. Expression. Function. Genomics. Localization. Orthologs. Paralogs. Pathways. Products. Proteins. Publications...
http://genecards.org/cgi-bin/carddisp.pl?gene=TNFRSF1B&rf=/home/genecards/current/website/carddisp.pl&unified_pathways=28
*  Template:Tumor necrosis factor receptor superfamily
template tumor necrosis factor receptor superfamily template tumor necrosis factor receptor superfamily redirect template cytokine receptors...
https://en.wikipedia.org/wiki/Template:Tumor_necrosis_factor_receptor_superfamily
*  SMART: Secondary literature for DEATH domain
2001; 75 : 8875-87 Display abstract Tumor necrosis factor TNF -related apoptosis-inducing ligand TRAIL induces apoptosis through two receptors, TRAIL-R1 also known as death receptor 4 and TRAIL-R2 also known as death receptor 5 , that are members of the TNF receptor superfamily of death domain-containing receptors. 2001; 98 : 6307-12 Display abstract FADD/Mort1, initially identified as a Fas-associated death-domain containing protein, functions as an adapter molecule in apoptosis initiated by Fas, tumor necrosis factor receptor-I, DR3, and TRAIL-receptors. 2001; 284 : 1109-15 Display abstract One of the most recently identified members of the tumor necrosis factor receptor family, death receptor-6 DR6 , has been shown to mediate apoptosis following overexpression in HeLa cells. 2000; 12 : 611-20 Display abstract Fas APO-1/CD95 and tumor necrosis factor receptor 1 TNFR1 trigger apoptosis by recruiting the apoptosis initiator caspase-8 through the adaptor FADD. 2000; 275 : 36217-22 Display abstract FADD is know...
http://smart.embl-heidelberg.de/smart/show_secondary.cgi?domain=DEATH
*  CD40 Gene - GeneCards | TNR5 Protein | TNR5 Antibody
CD40 Gene - GeneCards. TNR5 Protein. TNR5 Antibody. Free for academic non-profit institutions. Other users need a Commercial license. Keywords. Keywords. Symbols. Symbols/Aliases. Symbols/Aliases/Identifiers. Advanced. Home. User Guide. Analysis Tools. GeneAnalytics. VarElect. GeneAlaCart. GenesLikeMe. News And Views. About. Our Publications. Weizmann Institute. LifeMap Sciences Inc. Academic License Agreement. GeneCards Team. Log In /. Sign Up. My Genes. . GCID:. GC20P046118. GIFtS:. 64. CD40. Gene Protein Coding CD40 Molecule, TNF Receptor Superfamily Member 5. Research Products for CD40 Gene Antibodies. Proteins. More... Animal Models. Assays. Clones Epigenetics. In Situ Assays. miRNA. PCR Array. Proteins. CRISPR. Antibodies. Cell Lines. Compounds. Flow Cytometry. Inhib. RNA. Primers PCR Panel. Regul. Elements. Show less... Jump to section Aliases. Compounds. Disorders. Domains. Expression. Function. Genomics. Localization. Orthologs. Paralogs. Pathways. Products. Proteins. Publications. Sources. Summaries...
http://genecards.org/cgi-bin/carddisp.pl?gene=CD40
*  CD40 Gene - GeneCards | TNR5 Protein | TNR5 Antibody
CD40 Gene - GeneCards. TNR5 Protein. TNR5 Antibody. Free for academic non-profit institutions. Other users need a Commercial license. Keywords. Keywords. Symbols. Symbols/Aliases. Symbols/Aliases/Identifiers. Advanced. Home. User Guide. Analysis Tools. GeneAnalytics. VarElect. GeneAlaCart. GenesLikeMe. News And Views. About. Our Publications. Weizmann Institute. LifeMap Sciences Inc. Academic License Agreement. GeneCards Team. Log In /. Sign Up. My Genes. . GCID:. GC20P046118. GIFtS:. 64. CD40. Gene Protein Coding CD40 Molecule, TNF Receptor Superfamily Member 5. Research Products for CD40 Gene Antibodies. Proteins. More... Animal Models. Assays. Clones Epigenetics. In Situ Assays. miRNA. PCR Array. Proteins. CRISPR. Antibodies. Cell Lines. Compounds. Flow Cytometry. Inhib. RNA. Primers PCR Panel. Regul. Elements. Show less... Jump to section Aliases. Compounds. Disorders. Domains. Expression. Function. Genomics. Localization. Orthologs. Paralogs. Pathways. Products. Proteins. Publications. Sources. Summaries...
http://genecards.org/cgi-bin/carddisp.pl?gene=CD40&rf=/home/genecards/current/website/carddisp.pl&sabio_exp_pcr=21
*  Tumour necrosis factor receptor
... redirect tumor necrosis factor receptor...
https://en.wikipedia.org/wiki/Tumour_necrosis_factor_receptor
*  Decoy receptor 3
decoy receptor decoy receptor decoy receptor dcr also known as tumor necrosis factor receptor superfamily member b tnfrsf b tr and m is a soluble protein of the tumor necrosis factor receptor superfamily which inhibits fas ligand induced apoptosis discovery structure function interactions references further reading external links discovery dcr was identified in by the search of genes with homology to the tnfr gene superfamily in expressed sequence tag est database structure the open reading frame of tnfrsf b encodes amino acids with a residue signal sequence and four tandem cystein rich repeats two transcript variants encoding the same isoform but differing in the utr have been observed for this gene unlike most of the other members of tnfr superfamily tnfrsf is a soluble protein which contains no transmembrane domain function this gene belongs to the tumor necrosis factor receptor superfamily it acts as a decoy receptor that competes with death receptor s for ligand binding the encoded protein is postulated ...
https://en.wikipedia.org/wiki/Decoy_receptor_3
*  Genatlas sheet
HGNC name tumor necrosis factor receptor superfamily, member 1A. Corresponding disease TRAPS tumor necrosis receptor-associated periodic syndrome Location 12p13.2 Physical location : 6.437.923 - 6.451.283 Synonym name tumor necrosis factor receptor 1 55kDa. tumor necrosis factor-alpha receptor Synonym symbol s TNFR1, TR55, CD120A, TNFAR, TNFR60, FPF, TRAPS, TNF-R, TNF-R-I, TNF-R55, p55. expressed in based on citations organ s System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive esophagus. tissue System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Blood / Hematopoietic bone marrow. a N-Smase activation domain NSD is both necessary and sufficient for activation of N-Smase. FAMILY tumor necrosis factor receptor superfamily. important for the development of secondary lymphoid organs during embryonic life, and is required for the formation of splenic compartments during adult, but not embryonic life. TNFRSF1A, TNFRSF1B were req...
http://genatlas.medecine.univ-paris5.fr/fiche.php?symbol=TNFRSF1A
*  The role of a soluble TNFalpha receptor fusion protein (etanercept) in corticosteroid refractory ast
The role of a soluble TNFalpha receptor fusion protein etanercept in corticosteroid refractory asthma: a double blind, randomised, placebo controlled trial. Enbrel Baygam Buminate 25% Buminate 5% Gamimune N Optison Plasbumin-25 Plasbumin-5. The role of a soluble TNFalpha receptor fusion protein etanercept in corticosteroid refractory asthma: a double blind, randomised, placebo controlled trial. jbm@soton.ac.uk Publication date source: 2008-07, Thorax., 63 7 :584-91. METHODS: A randomised, double blind, placebo controlled parallel group trial is reported of etanercept an IgG1-TNF p75 receptor fusion protein, administered once weekly for 12 weeks in 39 patients with severe corticosteroid refractory asthma. Efficacy was measured by change from the pretreatment baseline in Asthma Related Quality of Life AQLQ and Asthma Control ACQ Questionnaire scores the primary endpoints, lung function, peak expiratory flow PEF and bronchial hyperresponsiveness BHR. Sputum and serum inflammatory cells and cytokines, serum album...
http://druglib.com/abstract/mo/morjaria-jb_thorax_20080700.html
*  Long-term safety and maintenance of clinical improvement following treatment with anakinra (recombin
Long-term safety and maintenance of clinical improvement following treatment with anakinra recombinant human interleukin-1 receptor antagonist in patients with rheumatoid arthritis: Extension phase of a randomized, double-blind, placebo-controlled trial - Nuki - 2002 - Arthritis Rheumatism - Wiley Online Library. Abstract. Research Article You have free access to this content Long-term safety and maintenance of clinical improvement following treatment with anakinra recombinant human interleukin-1 receptor antagonist in patients with rheumatoid arthritis: Extension phase of a randomized, double-blind, placebo-controlled trial. 2002 , Long-term safety and maintenance of clinical improvement following treatment with anakinra recombinant human interleukin-1 receptor antagonist in patients with rheumatoid arthritis: Extension phase of a randomized, double-blind, placebo-controlled trial. ARTICLE TOOLS Get PDF 93K Get PDF 93K. E-mail Link to this Article. Abstract. Article References. Cited By View Full Article HTM...
http://onlinelibrary.wiley.com/doi/10.1002/art.10578/references?globalMessage=0
*  Insect Cells Fas (TNF Receptor Superfamily, Member 6) (FAS) Protein, Recombinant | ABIN967460
Insect Cells Fas TNF Receptor Superfamily, Member 6 FAS Protein, Recombinant. Shipping to United States. Comparison list. No Products on your Comparison List. Basket. Antibodies. ELISA Kits. Secondary Antibodies. Proteins. Antibodies Primary antibodies Secondary antibodies Kits ELISA Kits Assay Kits Reagents Protein Peptide Lysate Isotype Control Accessory Reagent Suppliers Pathways. Antibodies Primary antibodies Secondary antibodies Kits ELISA Kits Assay Kits Reagents Protein Peptide Lysate Isotype Control Accessory Reagent Suppliers Pathways. Comparison list. Basket. Shipping to United States. Search, Find and Buy Antibodies, ELISA Kits and Proteins. All products. Antibodies. Secondary Antibodies. Kits. ELISA Kits. Proteins. Proteins. Fas TNF Receptor Superfamily, Member 6 FAS Soluble Protein. Fas TNF Receptor Superfamily, Member 6 FAS Soluble Protein. Details for Product No. Protein Name. Fas TNF Receptor Superfamily, Member 6 FAS. Soluble. Human. Insect Cells. coli 30 , Human Cells 11 , Yeast 8 , HEK-293 ...
http://antibodies-online.com/protein/967460/Fas TNF Receptor Superfamily Member 6 FAS Soluble/
*  tnfrsf19 - Zebrafish Mutation Project - Wellcome Trust Sanger Institute
... Jump to navigation. Jump to content. Search for. A A A A. Home. Research. Scientific resources. Work study. About us. Mouse. Zebrafish. Data. Software. Databases. Technologies. Talks training Search Zebrafish Mutation Project Search for:. e.g. ENSDARG00000093395 or slc2a11b or ENSG00000135862 or LAMC1 or sa457 You can look for mutant lines by browsing a complete list or by searching for a particular gene. tnfrsf19. Ensembl ID: ENSDARG00000041869 ZFIN ID: ZDB-GENE-030131-6760 Description: tumor necrosis factor receptor superfamily member 19 Human Orthologue: TNFRSF19 Human Description: tumor necrosis factor receptor superfamily, member 19 Mouse Orthologue: Tnfrsf19 Mouse Description: tumor necrosis factor receptor superfamily, member 19 Gene. Alleles There are 3 alleles of this gene: Allele name Consequence Status Availability Estimate sa3933 Essential Splice Site Mutation detected in F1 DNA During 2015. sa742 Nonsense Available for shipment Available now. sa6139 Nonsense Mutation detected in F1 DNA Durin...
http://sanger.ac.uk/sanger/Zebrafish_Zmpgene/ENSDARG00000041869
*  Death receptor 6
death receptor death receptor death receptor dr also known as tumor necrosis factor receptor superfamily member tnfrsf is a cell surface receptor of the tumor necrosis factor receptor superfamily which activates the jnk and nf κb pathways it is mostly expressed in the thymus spleen and white blood cells function clinical significance references further reading function the protein encoded by this gene is a member of the tnf receptor superfamily this receptor has been shown to activate nf κb and mapk jnk and induce cell apoptosis through its death domain this receptor interacts with tradd protein which is known to serve as an adaptor that mediates signal transduction of tnf receptors knockout studies in mice suggested that this gene plays a role in t helper cell activation and may be involved in inflammation and immune regulation clinical significance dr is also thought to be involved in neurodegeneration in the brain that causes alzheimer s disease as well as signal transduction in stress response and cellula...
https://en.wikipedia.org/wiki/Death_receptor_6
*  FAS Pre-design Chimera RNAi - (H00000355-R11) - Products - Abnova
FAS Pre-design Chimera RNAi - H00000355-R11 - Products - Abnova. Products. New Products. Protein Expression. Wheat Germ Protein. Need Mouse Protein. Mouse Mab. Mouse and Rabbit Pab. Rabbit Mab. CELLine Cell Culture. Transient Antibody Production. Stable Cell Line Antibody Production. Monoclonal Antibody. Recombinant Protein. Antibody Pair. Custom FISH Probes. Antibody Labeling. Circulating Tumor Cells. ELISA Pairs Kits. Fluorescence In Situ Hybridization FISH Probes. Secondary Antibody. Stem Cell. Mouse Mab. Rabbit Mab. Chimera RNAi. Membrane Protein. Protein+Antibody+Mass. Wheat Germ Protein. Antibody School. siRNA/Chimera. Ab Validated Chimera. Pre-design Chimera. Apoptosis FAS Pre-design Chimera RNAi FAS Pre-design Chimera RNAi Catalog # : H00000355-R11 Visit Frequency :. Product Description: Homo sapiens Fas TNF receptor superfamily, member 6 FAS, transcript variant 3, mRNA. The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence. Gene Summary...
http://abnova.com/Products/products_detail.asp?Catalog_id=H00000355-R11
*  TNFRSF18
... 'Tumor necrosis factor receptor superfamily member 18' TNFRSF18 also known as 'activation-inducible TNFR family receptor' AITR. or 'glucocorticoid-induced TNFR-related protein' GITR is a protein that in humans is encoded by the 'TNFRSF18' gene. GITR is currently of interest to immunologists as a co-stimulatory immune checkpoint molecule. TNFRSF18 is a member of the tumor necrosis factor receptor TNF-R superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 + / CD4 + regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3 -driven T-cell activation and programmed cell death. Human activation-inducible tumor necrosis factor receptor AITR and its ligand, AITRL, are important costimulatory molecules in the pathogenesis of autoimmune diseases. Despite the importance of these costimulatory molecules in autoimmune disease, ...
https://en.wikipedia.org/wiki/TNFRSF18
*  Etanercept
First, the developers isolated the DNA sequence that codes the human gene for soluble TNF receptor 2, which is a receptor that binds to tumor necrosis factor-alpha. Third, they linked the DNA for TNF receptor 2 to the DNA for IgG1 Fc. Finally, they expressed the linked DNA to produce a protein that links the protein for TNF receptor 2 to the protein for IgG1 Fc. A tumor necrosis factor TNF receptor-IgG heavy chain chimeric protein as a bivalent antagonist of TNF activity. Sales. publisher = Food and Drug Administration}} Moderate to Severe Polyarticular Juvenile Rheumatoid Arthritis May 1999. publisher = Food and Drug Administration}} Psoriatic Arthritis Jan 2002. url = http://www.accessdata.fda.gov/drugsatfda docs/nda/2003/103795-5123 Enbrel approv.pdf. publisher = Food and Drug Administration}}. There are two types of TNF receptor s: those found embedded in white blood cells that respond to TNF by releasing other cytokines, and 'soluble' TNF receptors which are used to deactivate TNF and blunt the immune re...
https://en.wikipedia.org/wiki/Etanercept
*  FAS (Human) IP-WB Antibody Pair - (H00000355-PW2) - Products - Abnova
FAS Human IP-WB Antibody Pair - H00000355-PW2 - Products - Abnova. Products. New Products. Protein Expression. Need Mouse Protein. Mouse Mab. Mouse and Rabbit Pab. Rabbit Mab. CELLine Cell Culture. Transient Antibody Production. Stable Cell Line Antibody Production. Monoclonal Antibody. Recombinant Protein. Antibody Pair. Custom FISH Probes. Antibody Labeling. Circulating Tumor Cells. ELISA Pairs Kits. Fluorescence In Situ Hybridization FISH Probes. Secondary Antibody. Stem Cell. Mouse Mab. Rabbit Mab. Chimera RNAi. Protein+Antibody+Mass. Antibody School. Pre-design Chimera. Apoptosis FAS Human IP-WB Antibody Pair FAS Human IP-WB Antibody Pair Catalog # : H00000355-PW2 Visit Frequency :. Product Description: This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot. Immunoprecipitation of FAS transfected lysate using mouse monoclonal anti-FAS and Protein A Magnetic Bead U0007 , and immunoblotted with rabbit polyclonal anti-FAS. ...
http://abnova.com/products/products_detail.asp?Catalog_id=H00000355-PW2&SL=EN
*  CD120
cd cd cd c luster of d ifferentiation can refer to two members of the tumor necrosis factor receptor superfamily tumor necrosis factor receptor tnfr and tumor necrosis factor receptor tnfr receptor subtypes signaling pathway see also references external links receptor subtypes there are two variants of the receptor each encoded by a separate gene cd a tnfr tnfr superfamily member a cd b tnfr tnfr superfamily member b tnfr is the receptor type responsible for mediation of tnf alpha induced sickness behavior and is involved in neurotoxic processes elevated levels of tnfr has been found in severe mental disorders signaling pathway image tnf signaling jpg thumb left px signaling pathway of tnf r dashed grey lines represent multiple steps see also cluster of differentiation references external links...
https://en.wikipedia.org/wiki/CD120
*  Death receptor 3
... 'Death receptor 3' 'DR3', also known as 'tumor necrosis factor receptor superfamily member 25' 'TNFRSF25', is a cell surface receptor of the tumor necrosis factor receptor superfamily which mediates apoptotic signalling and differentiation. Its only known ligand is TNF-like protein 1A TL1A. 4 Function Therapeutics References Further reading. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially by activated and antigen-experienced T lymphocytes. TNFRSF25 is also highly expressed by FoxP3 positive regulatory T lymphocytes. TNFRSF25 is activated by a monogamous ligand, known as TL1A TNFSF15, which is rapidly upregulated in antigen presenting cells and some endothelial cells following Toll-Like Receptor or Fc receptor activation. This receptor has been shown to signal both through the TRADD adaptor molecule to stimulate NF-kappa B activity or through the FADD adaptor molecule to stimulate caspase activation and regulate cell apoptosis. Specif...
https://en.wikipedia.org/wiki/Death_receptor_3
*  Death receptor 4
death receptor death receptor death receptor dr also known as trail receptor trailr and tumor necrosis factor receptor superfamily member a tnfrsf a is a cell surface receptor of the tnf receptor superfamily that binds trail and mediates apoptosis function interactions references further reading function interactions tnfrsf a has been shown to interact with dap references further reading category tnf receptor family category clusters of differentiation...
https://en.wikipedia.org/wiki/Death_receptor_4
*  Decoy receptor 1
decoy receptor decoy receptor decoy receptor dcr also known as trail receptor trailr and tumor necrosis factor receptor superfamily member c tnfrsf c is a human cell surface receptor of the tnf receptor superfamily function references further reading category clusters of differentiation category tnf receptor family...
https://en.wikipedia.org/wiki/Decoy_receptor_1
*  Decoy receptor 2
decoy receptor decoy receptor decoy receptor dcr also known as trail receptor trailr and tumor necrosis factor receptor superfamily member d tnfrsf d is a human cell surface receptor of the tnf receptor superfamily function references further reading category clusters of differentiation category tnf receptor family...
https://en.wikipedia.org/wiki/Decoy_receptor_2
*  how much does enbrel cost without insurance - MedHelp
... Full Site. Communities Health Tools Information My MedHelp Login or. General Health Diet and Fitness. Women's Health. Heart Heart Disease. Women's Health. Heart Disease. Help. How much does enbrel cost without insurance. Common Questions and Answers about How much does enbrel cost without insurance. enbrel. Read More. Read More. Remicade, Enbrel, etc that seem to work for some - but they cost like $5,000 per month and I think I would only like to go there as a last resort. Read More. Read More. I doubt anyone will tell you how much he will recover. Read More. Read More. No side effects, and costs only $30 per month without health insurance - the only possible downside is that it may not cure your incurable disease. Read More. This problem is interupting my life so much and I don't have any insurance anymore so I can't get any help. I feel like I have aged so much, I don't feel 28 at all. Read More. Read More. lots of stress chemicals in the blood for a long period of time - known to hurt nerves. My beta ...
http://healthquestions.medhelp.org/how-much-does-enbrel-cost-without-insurance
*  TNFRSF12A
tnfrsf a tnfrsf a tumor necrosis factor receptor superfamily member a also known as the tweak receptor tweakr is a protein that in humans is encoded by the tnfrsf a gene clinical significance nfat regulates the expression of tweakr this protein and its ligand tweak with lipocalin to increase breast cancer cell invasion references further reading category clusters of differentiation category tnf receptor family...
https://en.wikipedia.org/wiki/TNFRSF12A
*  Taking Enbrel and Percocet - Reviews
... Log in What is Treato. About Treato. Enbrel. Enbrel and Percocet. Enbrel. Share your experience. Enbrel for RA. We analyzed what people said about Enbrel and compared it to other RA medications. Share your experience. Enbrel and Percocet. Interaction between Enbrel and Percocet: Interaction not known, but may still exist. Always consult your doctor before taking these medications together. We found 207 discussions Share your experience Please keep in mind that posts are moderated. that : On my worse days I take percocet for the pain.... Comment. Helpful. Save. brex, enbrel & percocets only help me to just get by my d... Now I've been on Enbrel for about 2 years and it's helped a great deal but ...the celebrex, enbrel & percocets only... Comment. Helpful. Save. For that only Percocet seems to work. For that only Percocet seems to work. The Percocet also did work for my... Comment. Helpful. Save. ** Actually, I don't like Percocet. " ...mtracyfam ** Actually, I don't like Percocet. I get very drowsy and .....
http://treato.com/Enbrel,Percocet/?a=s
*  CD137
cd cd cd is a member of the tumor necrosis factor tnf receptor family its alternative names are tumor necrosis factor receptor superfamily member tnfrsf bb and induced by lymphocyte activation ila it is currently of interest to immunologists as a co stimulatory immune checkpoint molecule expression specific effects on cells interactions see also references further reading expression cd can be expressed by activated t cells but to a larger extent on cd than on cd t cells in addition cd expression is found on dendritic cells follicular dendritic cells natural killer cells granulocytes and cells of blood vessel walls at sites of inflammation specific effects on cells the best characterized activity of cd is its costimulatory activity for activated t cells crosslinking of cd enhances t cell proliferation il secretion survival and cytolytic activity further it can enhance immune activity to eliminate tumors in mice interactions cd has been shown to interact with traf see also bb ligand urelumab references further ...
https://en.wikipedia.org/wiki/CD137
*  RELT
... tumor necrosis factor receptor superfamily member l is a protein that in humans is encoded by the relt gene function the protein encoded by this gene is a member of the tnf receptor superfamily this receptor is especially abundant in hematologic tissues it has been shown to activate the nf kappab pathway and selectively bind tnf receptor associated factor traf this receptor is capable of stimulating t cell proliferation in the presence of cd signaling which suggests its regulatory role in immune response two alternatively spliced transcript variants of this gene encoding the same protein have been reported references...
https://en.wikipedia.org/wiki/RELT
*  BAG4
bag bag bag family molecular chaperone regulator is a protein that in humans is encoded by the bag gene function interactions references further reading function the protein encoded by this gene is a member of the bag related protein family bag is an anti apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including bcl raf protein kinase steroid hormone receptors growth factor receptors and members of the heat shock protein kda family this protein contains a bag domain near the c terminus which could bind and inhibit the chaperone activity of hsc hsp this protein was found to be associated with the death domain of tumor necrosis factor receptor type tnf r and death receptor dr and thereby negatively regulates downstream cell death signaling the regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost interactions bag has been shown to interact with ...
https://en.wikipedia.org/wiki/BAG4
*  TNFRSF19
tnfrsf tnfrsf tumor necrosis factor receptor superfamily member also known as tnfrsf and troy is a human gene references further reading category tnf receptor family...
https://en.wikipedia.org/wiki/TNFRSF19
*  Clinical trial: Open-Label Extension Treatment With Etanercept (TNFR:Fc) for Participating Patients
Clinical trial: Open-Label Extension Treatment With Etanercept TNFR:Fc for Participating Patients in Etanercept TNFR:Fc Clinical Trial 016.0012. Rx drug information, pharmaceutical research, clinical trials, news, and more. Drugs By Name By Condition By Category Most Searched Ratings/Reviews Adverse Events Actives. Related Drugs. Enbrel. Open-Label Extension Treatment With Etanercept TNFR:Fc for Participating Patients in Etanercept TNFR:Fc Clinical Trial 016.0012. Information source: Amgen ClinicalTrials.gov processed this data on August 20, 2015 Link to the current ClinicalTrials.gov record. Condition s targeted: Rheumatoid Arthritis Intervention: Etanercept Biological Phase: Phase 3 Status: Completed Sponsored by: Amgen Official s and/or principal investigator s : MD, Study Director, Affiliation: Amgen Summary This is an open label, multicenter study for extended treatment of patients who have participated in the Immunex clinical study 016. 0012. The primary objective of this study is to evaluate the long t...
http://druglib.com/trial/90/NCT00356590.html
*  Template:PBB/55504
template pbb template pbb gnf protein box name tumor necrosis factor receptor superfamily member image image source pdb hgncid mgiid symbol tnfrsf altsymbols taj taj alpha trade troy iuphar yes chembl omim ecnumber homologene geneatlas image geneatlas image geneatlas image protein domain image function component gnf go id go text intracellular gnf go id go text integral component of membrane process gnf go id go text hair follicle development gnf go id go text apoptotic process gnf go id go text jnk cascade gnf go id go text tumor necrosis factor mediated signaling pathway gnf go id go text positive regulation of i kappab kinase nf kappab signaling hs entrezgene hs ensembl ensg hs refseqmrna nm hs refseqprotein np hs genloc db hg hs genloc chr hs genloc start hs genloc end hs uniprot q ns mm entrezgene mm ensembl ensmusg mm refseqmrna nm mm refseqprotein np mm genloc db mm mm genloc chr mm genloc start mm genloc end mm uniprot q jll path pbb...
https://en.wikipedia.org/wiki/Template:PBB/55504
*  Enbrel and Nausea - Suspected Cause - Reports of Side Effects
Reported by a physician from United States on 2012-08-24 Patient: 54 year old female Reactions: Breast Cancer, Rheumatoid Arthritis, Vomiting, Nausea Adverse event resulted in: hospitalization Drug s suspected as cause: Enbrel Other drugs received by patient: Methotrexate Possible Enbrel side effects in 10 year old female. Reported by a physician from United States on 2012-08-06 Patient: 26 year old female Reactions: Back Pain, Nausea, Injection Site Pain, Paraesthesia, Anxiety, Fatigue, Palpitations, Visual Impairment, Dizziness, Depression, Feeling Abnormal, Sinusitis, Asthenia, Influenza Like Illness Drug s suspected as cause: Enbrel Dosage: 50 mg, qwk Start date: 2011-06-22 Enbrel Dosage: 50 mg, qwk Indication: Rheumatoid Arthritis Start date: 2011-05-05 Other drugs received by patient: Paxil Possible Enbrel side effects in 68 year old female. Reported by a physician from United States on 2012-08-02 Patient: 43 year old male, weighing 127.0 kg 279.4 pounds Reactions: Nausea, Injection Site Haemorrhage, In...
http://druglib.com/reported-side-effects/enbrel/reaction_nausea/
*  www.arthritis-research.com - Table
... Table 2. Differentially expressed genes in RASFsn-stimulated chondrocytes FC ≥ 1,5; FC ≤ -1,5; GCOS. Functional annotation: gene title gene symbol. Accession no. Chondrocyte mean fold change in expression GCOS analysis. Chondrocyte mean signal intensity GCOS analysis. RASFsn versus NDSFsn stimulation. RASFsn stimulation. NDSFsn stimulation. No stimulation. Inflammatory/catabolic mediators. NM 001752.1. Chemokine C-C motif ligand 5 RANTES. NM 002985.1. Chemokine orphan receptor 1 CMKOR1. Interleukin-1β IL-1β. Interleukin-6 IL-6. NM 000600.1. Nuclear factor-κB associated gene NF-κB1. NM 003998.1. Nuclear factor-κB associated gene NF-κB2. NM 004878.1. NM 006291.1. Tumor necrosis factor receptor TNFRSF1B. NM 001066.1. ECM degradation. Matrix metalloproteinase 10 MMP10. NM 002425.1. Matrix metalloproteinase 12 MMP12. NM 002426.1. ECM formation. Collagen, type I, α1 COL1A1. NM 000088.1. Collagen, type V, α1 COL5A1. Expression levels of rheumatoid arthritis-relevant genes that failed to reach the twofold regula...
http://arthritis-research.com/content/10/1/R9/table/T2
*  Pegsunercept
... drugbox verifiedfields changed verifiedrevid iupac name tradename pregnancy category legal status investigational routes of administration subcutaneous injection bioavailability n a metabolism elimination half life excretion cas number ref cas number atc prefix none atc suffix pubchem drugbank ref pegsunercept is a drug for the treatment of rheumatoid arthritis phase ii clinical trial s have been completed it is being developed by amgen similarly to etanercept pegsunercept is a soluble tumor necrosis factor receptor pegsunercept is a pegylated protein references category tnf inhibitors category immunosuppressants...
https://en.wikipedia.org/wiki/Pegsunercept
*  T cells go universal - BioCentury.com
... Jude product targets the Fc portion of a human antibody that binds to a cancer-associated antigen. The team reasoned that T cells expressing CD16 would engage in ADCC toward the cancer cells and selected a variant of CD16 with high affinity for antibodies. Jude chimeric receptor was made up of CD3z and tumor necrosis factor receptor superfamily member 9 TNFRSF9 ; 4-1BB ; CD137 , which induce T cell activation, proliferation and antitumor activity in T cells expressing antigen-specific CARs. 3 The resulting product was T cells that express a universal chimeric receptor that targets the constant region of the Fc portion of antibodies. The next step was showing that the CD16-BB-z-expressing T cells could target more than one tumor antigen. T cells expressing CD16-BB-z induced significantly higher levels of ADCC than T cells expressing CD16 alone or those expressing the CD16-FCER1G fusion protein p 0.0001 , as well as much more vigorous T cell expansion. In immunodeficient animals with human B lymphoblast ce...
http://biocentury.com/innovations/coverstory/2013-12-12/cover-story-t-cells-go-universal-s1
*  Template:PBB/8793
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https://en.wikipedia.org/wiki/Template:PBB/8793
*  Template:PBB/8794
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https://en.wikipedia.org/wiki/Template:PBB/8794
*  Template:PBB/4982
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https://en.wikipedia.org/wiki/Template:PBB/4982
*  Template:PBB/3604
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https://en.wikipedia.org/wiki/Template:PBB/3604
*  Template:PBB/8784
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https://en.wikipedia.org/wiki/Template:PBB/8784
*  Template:PBB/8792
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https://en.wikipedia.org/wiki/Template:PBB/8792
*  Template:PBB/8718
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https://en.wikipedia.org/wiki/Template:PBB/8718
*  Template:PBB/943
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https://en.wikipedia.org/wiki/Template:PBB/943
*  Template:PBB/8797
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https://en.wikipedia.org/wiki/Template:PBB/8797
*  Template:PBB/115650
template pbb template pbb gnf protein box name tumor necrosis factor receptor superfamily member c image protein tnfrsf c pdb oqe png image source pdb rendering based on oqe pdb process hs entrezgene hs ensembl ensg hs refseqmrna nm hs refseqprotein np hs genloc db hg hs genloc chr hs genloc start hs genloc end hs uniprot q rj mm entrezgene mm ensembl ensmusg mm refseqmrna nm mm refseqprotein np mm genloc db mm mm genloc chr mm genloc start mm genloc end mm uniprot q d d path pbb...
https://en.wikipedia.org/wiki/Template:PBB/115650
*  Template:PBB/51330
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https://en.wikipedia.org/wiki/Template:PBB/51330
*  Template:PBB/23495
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https://en.wikipedia.org/wiki/Template:PBB/23495
*  Template:PBB/27242
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https://en.wikipedia.org/wiki/Template:PBB/27242
*  Template:PBB/608
template pbb template pbb gnf protein box name tumor necrosis factor receptor superfamily member image protein tnfrsf pdb oqd png image source pdb rendering based on oqd pdb hs entrezgene hs ensembl ensg hs refseqmrna nm hs refseqprotein np hs genloc db hg hs genloc chr hs genloc start hs genloc end hs uniprot q mm entrezgene mm ensembl ensmusg mm refseqmrna nm mm refseqprotein np mm genloc db mm mm genloc chr mm genloc start mm genloc end mm uniprot o path pbb...
https://en.wikipedia.org/wiki/Template:PBB/608
*  Template:PBB/8764
template pbb template pbb gnf protein box name tumor necrosis factor receptor superfamily member image protein tnfrsf pdb jma png image source pdb rendering based on jma pdb process hs entrezgene hs ensembl ensg hs refseqmrna nm hs refseqprotein np hs genloc db hg hs genloc chr hs genloc start hs genloc end hs uniprot q mm entrezgene mm ensembl ensmusg mm refseqmrna nm mm refseqprotein np mm genloc db mm mm genloc chr mm genloc start mm genloc end mm uniprot b azn path pbb...
https://en.wikipedia.org/wiki/Template:PBB/8764
*  Template:PBB/7132
template pbb template pbb gnf protein box name tumor necrosis factor receptor superfamily member a image protein tnfrsf a pdb ext png image source pdb rendering based on ext pdb process hs entrezgene hs ensembl ensg hs refseqmrna nm hs refseqprotein np hs genloc db hg hs genloc chr hs genloc start hs genloc end hs uniprot p mm entrezgene mm ensembl ensmusg mm refseqmrna nm mm refseqprotein np mm genloc db mm mm genloc chr mm genloc start mm genloc end mm uniprot p path pbb...
https://en.wikipedia.org/wiki/Template:PBB/7132
*  Template:PBB/7293
template pbb template pbb gnf protein box name tumor necrosis factor receptor superfamily member image protein tnfrsf pdb hev png image source pdb rendering based on hev pdb hs entrezgene hs ensembl ensg hs refseqmrna nm hs refseqprotein np hs genloc db hg hs genloc chr hs genloc start hs genloc end hs uniprot p mm entrezgene mm ensembl ensmusg mm refseqmrna nm mm refseqprotein np mm genloc db mm mm genloc chr mm genloc start mm genloc end mm uniprot p path pbb...
https://en.wikipedia.org/wiki/Template:PBB/7293
*  Template:PBB/8795
template pbb template pbb gnf protein box name tumor necrosis factor receptor superfamily member b image protein tnfrsf b pdb d g png image source pdb rendering based on d g pdb component process hs entrezgene hs ensembl ensg hs refseqmrna nm hs refseqprotein np hs genloc db hg hs genloc chr hs genloc start hs genloc end hs uniprot o mm entrezgene mm ensembl mm refseqmrna mm refseqprotein mm genloc db mm mm genloc chr mm genloc start mm genloc end mm uniprot path pbb...
https://en.wikipedia.org/wiki/Template:PBB/8795
*  Template:PBB/8771
template pbb template pbb gnf protein box name tumor necrosis factor receptor superfamily member b decoy image image source pdb component process hs entrezgene hs ensembl ensg hs refseqmrna nm hs refseqprotein np hs genloc db hg hs genloc chr hs genloc start hs genloc end hs uniprot o mm entrezgene mm ensembl mm refseqmrna mm refseqprotein mm genloc db mm mm genloc chr mm genloc start mm genloc end mm uniprot path pbb...
https://en.wikipedia.org/wiki/Template:PBB/8771
*  Template:PBB/7133
template pbb template pbb gnf protein box name tumor necrosis factor receptor superfamily member b image image source pdb process hs entrezgene hs ensembl ensg hs refseqmrna nm hs refseqprotein np hs genloc db hg hs genloc chr hs genloc start hs genloc end hs uniprot p mm entrezgene mm ensembl ensmusg mm refseqmrna nm mm refseqprotein np mm genloc db mm mm genloc chr mm genloc start mm genloc end mm uniprot p path pbb...
https://en.wikipedia.org/wiki/Template:PBB/7133
*  CD27
cd cd cd is a member of the tumor necrosis factor receptor superfamily it is currently of interest to immunologists as a co stimulatory immune checkpoint molecule function interactions references further reading external links function the protein encoded by this gene is a member of the tnf receptor superfamily this receptor is required for generation and long term maintenance of t cell immunity it binds to ligand cd and plays a key role in regulating b cell activation and immunoglobulin synthesis this receptor transduces signals that lead to the activation of nf κb and mapk jnk adaptor proteins traf and traf have been shown to mediate the signaling process of this receptor cd binding protein siva a proapoptotic protein can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor interactions cd has been shown to interact with siva traf and traf references further reading external links...
https://en.wikipedia.org/wiki/CD27
*  The Mathematical Tourist: Tilings at the Taj Mahal
... skip to main. skip to sidebar. The Mathematical Tourist. September 12, 2010. Tilings at the Taj Mahal. The breathtaking, glowingly extravagant Taj Mahal in Agra, India, is not only a memorial to Mumtaz Mahal, third wife of Mughal emperor Shah Jahan, but also a tribute to mirror symmetry. The Taj Mahal's translucent white marble has a warm glow in the early morning light. Click on photos to see more detail. Oriented on north-south and east-west axes, the mausoleum and its associated structures were designed around principles of reflection and repetition. The tomb itself is essentially a cube with chamfered corners, to give it an octagonal cross section see " Octagons and Squares ". The four sides are identical, each one featuring a huge vaulted archway. Four minarets frame the tomb. The Taj Mahal's symmetrical structure is evident in this northward view of the tomb. Reflection symmetries also abound in the decorations, made from precious and semiprecious stones inlaid on white, translucent marble below. E...
http://mathtourist.blogspot.com/2010/09/tilings-at-taj-mahal.html
*  TNF receptor
... redirect tumor necrosis factor receptor...
https://en.wikipedia.org/wiki/TNF_receptor
*  TNF-alpha receptor
tnf alpha receptor tnf alpha receptor redirect tumor necrosis factor receptor...
https://en.wikipedia.org/wiki/TNF-alpha_receptor
*  TNF-receptor
tnf receptor tnf receptor redirect tumor necrosis factor receptor...
https://en.wikipedia.org/wiki/TNF-receptor
*  Death receptor
... redirect tumor necrosis factor receptor...
https://en.wikipedia.org/wiki/Death_receptor
*  TNFRSF1A (gene)
tnfrsf a gene tnfrsf a gene redirect tumor necrosis factor receptor...
https://en.wikipedia.org/wiki/TNFRSF1A_(gene)
*  TNFRSF1B (gene)
tnfrsf b gene tnfrsf b gene redirect tumor necrosis factor receptor...
https://en.wikipedia.org/wiki/TNFRSF1B_(gene)
*  TNFR
... redirect tumor necrosis factor receptor...
https://en.wikipedia.org/wiki/TNFR
*  TNFR1
tnfr tnfr redirect tumor necrosis factor receptor...
https://en.wikipedia.org/wiki/TNFR1
*  Product Inquiry - United States Biological
... Login. Email. Password. Forgot your password. New User. Remember me. Home. Distributors. Technical. About. Register. Antibodies. Biochemicals. Culture Media. Custom Services. Growth Factors. Bioassay Kits. Lectins. Molecular Biology. Serum, Tissues. Protocols. Newsletter. About Us. Contact. . Product Inquiry Product Name. Tumor Necrosis Factor Receptor Associated Factor 6, CT TRAF-6. Product Code. T9161-65. Name. Email. Organization. Comments or Questions....
http://usbio.net/inquiry.php?item=T9161-65
*  CD120a
cd a cd a redirect tumor necrosis factor receptor...
https://en.wikipedia.org/wiki/CD120a
*  The Role of Endogenous Glucocorticoids in Autoimmune Arthritis - Research Supervisor Connect - Futu
More about this supervisor... Markus Seibel has passion for basic and clinical research into the many aspects of bone health and biology and is an internationally recognised researcher in the field of bone metabolism. More about this supervisor... Summary This is ongoing project to define the role and machinism of endogenous glucocorticoids in autoimmune arthritis. While the effects of these exogenous glucocorticoids on inflammatory pro cesses are well researched, the role of endogenous glucocorticoids in autoimmune arthritis remains unknown. Using cutting-edge transgenic technology, we have found that disruption of glucocorticoid signalling in bone forming cells osteoblasts severely blunts autoimmune arthritis in mice recently published in Arthritis Rheum, 2009. These unexpected and exciting findings indicate that osteoblasts are able to modulate the immune-mediated inflammatory response via a gluco corticoid-dependent pathway. Project hypothesis: Osteoblasts, under the control of endogen ous glucocorticoids...
http://sydney.edu.au/research/opportunities/opportunities/1159
*  Glucocorticoid use, other associated factors, and the risk of tuberculosis - Jick - 2006 - Arthritis
... Care Research - Wiley Online Library. Arthritis Care Research. JOURNAL MENU Journal Home FIND ISSUES Current Issue. All Issues FIND ARTICLES Early View. Original Articles You have free access to this content Glucocorticoid use, other associated factors, and the risk of tuberculosis. Lieberman 2 , Mahboob U. Rahman 3 and Hyon K. Choi 4,* Article first published online: 6 FEB 2006 DOI: 10.1002/art.21705 Copyright 2006 by the American College of Rheumatology. Arthritis Care Research Volume 55 , Issue 1 , pages 19 26 , 15 February 2006. K 2006 , Glucocorticoid use, other associated factors, and the risk of tuberculosis. Author Information 1 Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, Massachusetts 2 Massachusetts General Hospital, Harvard Medical School, Boston, and Summit Medical Group, Summit, New Jersey 3 Centocor Inc., Malvern, Pennsylvania 4 Massachusetts General Hospital, Harvard Medical School, Boston Email: Hyon K. Publication History Issue publish...
http://onlinelibrary.wiley.com/doi/10.1002/art.21705/abstract
*  Rapid glucocorticoid effects on excitatory amino acid levels in the hippocampus: a microdialysis stu
... dy in freely moving rats - Venero - 2008 - European Journal of Neuroscience - Wiley Online Library. European Journal of Neuroscience. JOURNAL TOOLS Get New Content Alerts. JOURNAL MENU Journal Home FIND ISSUES Current Issue. All Issues. Virtual Issues FIND ARTICLES Early View. Rapid glucocorticoid effects on excitatory amino acid levels in the hippocampus: a microdialysis study in freely moving rats. C sar Venero and Jos Borrell Article first published online: 9 OCT 2008 DOI: 10.1046/j.1460-9568.1999.00668.x. European Journal of Neuroscience Volume 11 , Issue 7 , pages 2465 2473 , July 1999. 1999 , Rapid glucocorticoid effects on excitatory amino acid levels in the hippocampus: a microdialysis study in freely moving rats. European Journal of Neuroscience, 11: 2465 2473. Borrell, Psychobiology Research Group, Cajal Institute, CSIC, Avda Dr Arce 37, 28002 Madrid, Spain E-mail: cgjb@cajal.csic.es. Publication History Issue published online: 9 OCT 2008 Article first published online: 9 OCT 2008 Received 12 Ja...
http://onlinelibrary.wiley.com/doi/10.1046/j.1460-9568.1999.00668.x/full
*  Preoperative Glucocorticoid Use in Major Hepatectomy - Full Text View - ClinicalTrials.gov
... Skip to Main Content. A service of the U.S. National Institutes of Health Example: "Heart attack" AND "Los Angeles" Search for studies:. Advanced Search. Help. Studies by Topic. Glossary. Find Studies. Basic Search. Advanced Search. See Studies by Topic. See Studies on Map. How to Search. How to Use Search Results. How to Find Results of Studies. How to Read a Study Record. About Clinical Studies. Learn About Clinical Studies. Other Sites About Clinical Studies. Glossary of Common Site Terms. Submit Studies. Why Should I Register and Submit Results. FDAAA 801 Requirements. How to Apply for an Account. How to Register Your Study. How to Edit Your Study Record. How to Submit Your Results. Frequently Asked Questions. Support Materials. Training Materials. Resources. Selected Publications. Clinical Alerts and Advisories. RSS Feeds. Trends, Charts, and Maps. Downloading Content for Analysis. About This Site. ClinicalTrials.gov Background. About the Results Database. History, Policies, and Laws. Media/Press Re...
https://clinicaltrials.gov/ct2/show/NCT01997658?recr=Open&intr="Glucocorticoids"&rank=15
*  Glucocorticoid action in asthma and COPD
... Endocrine Abstracts. ISSN 1470-3947 print ISSN 1479-6848 online Searchable abstracts of presentations at key conferences in endocrinology. Endocrine Abstracts 2005 9 S30. Glucocorticoids are by far the most effective anti-inflammatory therapy for asthma and many other inflammatory diseases. This involves binding of GR to coactivator proteins and acetylation of core histones, particularly histone-4 through the intrinsic histone acetyltransferase HAT activity of these coactivators. But most of the anti-inflammatory effects of glucocorticoids are mediated via suppression of inflammatory genes. These have been activated by pro-inflammatory transcription factors, such as nuclear factor-kB and activator protein-1, through histone-4 acetylation with a different acetylation pattern from glucocorticoid-mediated activation. Activated GR interacts with coactivators associated with inflammatory genes such as cytokines and directly inhibits their HAT activity, but more importantly recruits histone deacetylase HDAC 2 ...
http://endocrine-abstracts.org/ea/0009/ea0009s30.htm
*  Glucocorticoids synthetic - Biology-Online Dictionary
... Join for Free. Login. Welcome to Biology Online. Login. Remember me. Answers to all your biology questions Home. Blog. Forum. Dictionary. Articles. Tutorials. Books. Directory. Share. Search. Quick links: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9 OTHER View. View source. History. Glucocorticoids synthetic Glucocorticoids, synthetic. Science: chemical synthetic chemical compounds which increase gluconeogenesis, raising the concentration of liver glycogen and blood sugar, but differ in structure from naturally occurring glucocorticoids. Pharmacological action: steroidal anti-inflammatory agents, topical anti-inflammatory agents. Retrieved from " http://www.biology-online.org/bodict/index.php?title=Glucocorticoids synthetic oldid=55160 " First. Previous Glucocorticoids. Next Glucocorticoids topical. Last. Please contribute to this project, if you have more information about this term feel free to edit this page. This page was last modified on 3 October 2005, at 21:16.This page has been accesse...
http://biology-online.org/dictionary/Glucocorticoids_synthetic
*  Neural regulation of the stress response: glucocorticoid feedback mechanisms
... English epdf. Article in xml format. How to cite this article. Automatic translation. Send this article by e-mail. Cited by SciELO. Related links. Neural regulation of the stress response : glucocorticoid feedback mechanisms. The mammalian stress response is an integrated physiological and psychological reaction to real or perceived adversity. Glucocorticoids are an important component of this response, acting to redistribute energy resources to both optimize survival in the face of challenge and to restore homeostasis after the immediate challenge has subsided. Release of glucocorticoids is mediated by the hypothalamo-pituitary-adrenal HPA axis, driven by a neural signal originating in the paraventricular nucleus PVN. Stress levels of glucocorticoids bind to glucocorticoid receptors in multiple body compartments, including the brain, and consequently have wide-reaching actions. For this reason, glucocorticoids serve a vital function in negative feedback inhibition of their own secretion. Negative feedba...
http://scielo.br/scielo.php?script=sci_abstract&pid=S0100-879X2012000400002&lng=en&nrm=iso&tlng=en
*  Glucocorticoids
... redirect glucocorticoid...
https://en.wikipedia.org/wiki/Glucocorticoids
*  .. corticosteroids
corticosteroids by admin nov steroids released from the adrenal cortex corticosteroids include both mineralocorticoids and glucocorticoids mineralocorticoids maintain salt and fluid balance in the body while glucocorticoids have metabolic and anti inflammatory effects and are important mediators of the stress response related articles glucocorticoids related terms term anti inflammatory term adrenal cortex term glucocorticoids term stress response term metabolic...
http://web.stanford.edu/group/hopes/cgi-bin/hopes_test/glossary/corticosteroids/
*  Glucocorticoid Levels in Blood - Help!
http://bio.net/bionet/mm/immuno/1996-October/008769.html

(1/166) Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR.

The tumor necrosis factor (TNF) and TNF receptor (TNFR) gene superfamilies regulate diverse biological functions, including cell proliferation, differentiation, and survival [1] [2] [3]. We have identified a new TNF-related ligand, designated human GITR ligand (hGITRL), and its human receptor (hGITR), an ortholog of the recently discovered murine glucocorticoid-induced TNFR-related (mGITR) protein [4]. The hGITRL gene mapped to chromosome 1q23, near the gene for the TNF homolog Fas/CD95 ligand [5]. The hGITR gene mapped to chromosome 1p36, near a cluster of five genes encoding TNFR homologs [1] [6]. We found hGITRL mRNA in several peripheral tissues, and detected hGITRL protein on cultured vascular endothelial cells. The levels of hGITR mRNA in tissues were generally low; in peripheral blood T cells, however, antigen-receptor stimulation led to a substantial induction of hGITR transcripts. Cotransfection of hGITRL and hGITR in embryonic kidney 293 cells activated the anti-apoptotic transcription factor NF-kappaB, via a pathway that appeared to involve TNFR-associated factor 2 (TRAF2) [7] and NF-kappaB-inducing kinase (NIK) [8]. Cotransfection of hGITRL and hGITR in Jurkat T leukemia cells inhibited antigen-receptor-induced cell death. Thus, hGITRL and hGITR may modulate T lymphocyte survival in peripheral tissues.  (+info)

(2/166) CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor.

CD4(+)CD25(+) immunoregulatory T cells represent a unique lineage of thymic-derived cells that potently suppress both in vitro and in vivo effector T cell function. We analyzed CD4(+)CD25(+) and CD4(+)CD25(-) T cells by DNA microarray, identifying 29 genes differentially expressed in the resting subpopulations, and 77 that were differentially expressed following activation. Most of these genes were elevated in the CD4(+)CD25(+) population, suggesting a previously activated phenotype. Among these were a number of genes that antagonize signaling, including members of the SOCS family, which may contribute to their anergic phenotype. Multiple cell surface receptors also had increased expression in CD4(+)CD25(+) cells, including GITR, a member of the TNF receptor superfamily. Importantly, antibodies to GITR abrogated suppression, demonstrating a functional role for this receptor in regulating the CD4(+)CD25(+) T cell subset.  (+info)

(3/166) Recombinant glucocorticoid induced tumor necrosis factor receptor (rGITR) induces NOS in murine macrophage.

Glucocorticoid induced tumor necrosis factor receptor (GITR) is a new member of the tumor necrosis factor-nerve growth factor receptor superfamily of which the function has not been well studied. The extracellular domain of GITR was produced in Escherichia coli and purified as a single band of predicted M(r) of 18.0 kDa. GITR and GITR ligand were expressed constitutively on the surface of Raw 264.7 macrophage cell line and murine peritoneal macrophages. An extracellular domain of GITR can activate murine macrophages to express inducible nitric oxide synthase and to generate nitric oxide in a dose- and time-dependent manner.  (+info)

(4/166) Role of GITR in activation response of T lymphocytes.

In this study, we describe the generation and characterization of mice in which GITR gene (TNFRSF18 [tumor necrosis factor receptor superfamily 18]), a member of the TNFRSF expressed mainly on T lymphocytes, has been ablated (GITR(-/-) mice). Results indicate that GITR inactivation does not impair the normal development of the lymphoid organs but modulates T-cell activation. In fact, when GITR(-/-) T lymphocytes are activated by treatment with an anti-CD3 monoclonal antibody they proliferate more than wild-type cells. Moreover, activated GITR(-/-) T lymphocytes express higher levels of interleukin-2 receptor, produce larger amounts of interleukin-2, and are more sensitive to activation-induced cell death than controls. These results suggest that GITR is involved in the regulation of T-cell receptor/CD3-driven T-cell activation and programmed cell death.  (+info)

(5/166) Inhibition of human CD4(+)CD25(+high) regulatory T cell function.

CD4(+)CD25(+high) T cells are potent regulators of autoreactive T cells. However, it is unclear how regulatory CD4(+)CD25(+high) cells discriminate between desirable inflammatory immune responses to microbial Ags and potentially pathologic responses by autoreactive T cells. In this study, an in vitro model was created that allowed differential activation of regulatory CD4(+)CD25(+high) and responder CD4(+) T cells. If CD4(+)CD25(+high) regulatory cells were strongly activated, they maintained suppressive effector function for only 15 h, while stimulation with weaker TCR stimuli produced regulatory cells that were suppressive until 60 h after activation. In contrast, strongly activated CD4(+) responder T cells were resistant to regulation at all time points, while weakly stimulated CD4(+) cells were sensitive to suppression until 38 or 60 h after activation depending upon the strength of the stimulus. The extent of suppression mediated by CD4(+)CD25(+high) cells also depended on the strength of stimulation in an Ag-specific system. Thus, the stronger the TCR signal, the more rapidly and more completely the responder cells become refractory to suppression.  (+info)

(6/166) Regulation of murine inflammatory bowel disease by CD25+ and CD25- CD4+ glucocorticoid-induced TNF receptor family-related gene+ regulatory T cells.

CD4(+)CD25(+) regulatory T cells in normal animals are engaged in the maintenance of immunological self-tolerance and prevention of autoimmune disease. However, accumulating evidence suggests that a fraction of the peripheral CD4(+)CD25(-) T cell population also possesses regulatory activity in vivo. Recently, it has been shown glucocorticoid-induced TNFR family-related gene (GITR) is predominantly expressed on CD4(+)CD25(+) regulatory T cells. In this study, we show evidence that CD4(+)GITR(+) T cells, regardless of the CD25 expression, regulate the mucosal immune responses and intestinal inflammation. SCID mice restored with the CD4(+)GITR(-) T cell population developed wasting disease and severe chronic colitis. Cotransfer of CD4(+)GITR(+) population prevented the development of CD4(+)CD45RB(high) T cell-transferred colitis. Administration of anti-GITR mAb-induced chronic colitis in mice restored both CD45RB(high) and CD45RB(low) CD4(+) T cells. Interestingly, both CD4(+)CD25(+) and CD4(+)CD25(-) GITR(+) T cells prevented wasting disease and colitis. Furthermore, in vitro studies revealed that CD4(+)CD25(-)GITR(+) T cells as well as CD4(+)CD25(+)GITR(+) T cells expressed CTLA-4 intracellularly, showed anergic, suppressed T cell proliferation, and produced IL-10 and TGF-beta. These data suggest that GITR can be used as a specific marker for regulatory T cells controlling mucosal inflammation and also as a target for treatment of inflammatory bowel disease.  (+info)

(7/166) Induction of nitric oxide synthase (NOS) by soluble glucocorticoid induced tumor necrosis factor receptor (sGITR) is modulated by IFN-gamma in murine macrophage.

Earlier study showed that glucocorticoid induced tumor necrosis factor receptor (GITR), a new TNFR family, activated murine macrophages to express inducible nitric oxide synthase (iNOS) and to generate nitric oxide (NO). A possible involvement of pro-inflammatory cytokines on NO production by GITR was investigated in vitro systems and signaling molecules contributing to sGITR-induced iNOS production are determined in Raw 264.7 cells, a murine macrophage cell line. The result showed that the synergy was afforded by the combination of GITR with IFN-g in a dose-dependent manner but IFN-gamma alone was not able to induce NOS. No effects were observed with TNF-alpha, IL-1beta, or IL-6 co-treated with GITR. To determine signaling molecules contributing to sGITR-induced iNOS production, a specific inhibitor for signal pathway proteins tested showed that PDTC (NF-kappaB) and genistein (tyrosine kinase) inhibited NOS induction significantly, while sodium orthovanadate (tyrosine phosphatase) potentiated NOS expression. These results suggest that activations of NF-kappaB were involved in induction of iNOS by GITR and IFN-gamma priming caused earlier and stronger NF-kappaB activation.  (+info)

(8/166) Soluble glucocorticoid-induced TNF receptor (sGITR) induces inflammation in mice.

Glucocorticoid-induced TNF receptor (GITR) was a new member of the TNF/nerve growth factor receptor (TNFR/ NGFR) family and induced in murine T cells by dexamathasone. Recombinant soluble GITR (sGITR) induced an inflammation in peritoneal membrane and changes in spleen after i.p. injection of 3 mg/kg in C57BL/6 mice. Spleen was enlarged and percentage of neutrophils and monocytes were increased. The area of red pulp in spleen was increased, while that of white pulp was decreased after GITR injection. The thickening of membrane and neutrophil infiltration was observed in peritoneal membrane with increased myeloperoxidase activity. At later time, neutrophil infiltration moved to inside the tissue with tissue damage. GITR ligand and GITR were expressed constitutively on the surface of spleen cells and cells from peritoneal fluid. In contrast, no significant change in the spleen and in peritoneal membrane was observed in mice treated with LPS. GITR may play a role in body's inflammatory processes.  (+info)


How much protein powder should I add to muffin recipes to make them like the store-bought bars?


I love the protein bars you can buy in stores.  But I have yet to find a recipe to make one that looks good.  Does anyone have any favorite recipes that taste like the protein bars at the store?

Also if I make my own by using a normal muffin recipe, how much protein powder should I add to the batch?  I want them high protein and low calorie/low fat.
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I try to get a lot of protein in my diet so I do a lot of experimenting with protein powders that you can add to other recipes.  I usually start with two servings of whatever protein powder I have and add it to the recipe.  You may have to play around with the recipe to get the correct dry ingredient/wet ingredient ratio.  

I also make these bran muffins.

http://www.cupcakerecipes.com/bran-muffin-recipe.html

They are high in protein and REALLY good.  I use either wheat bran or oat bran.  You can also eat them with peanut butter to add more protein but you increase the calories quite a bit.  

Hope this helps. :)


How much protein is in one egg white? Is there any protein in the yolk?


How much protein is in one egg white? Is there any protein in the yolk?
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An egg white (raw) contains about 3.6 grams of protein. The egg yolk (also raw) contains about 2.7 grams of protein.


How many grams of protein is sufficient for an energy boost?


Protein bars and shakes have over 40g of protein, but how much is needed to get a little energy?  8g? 12g?
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How much protein do you need? The amount of protein that you need depends on your appropriate body weight, whether you are trying to build or just maintain your muscle mass, and how many total calories that you usually eat.
You can: 
1. Determine your daily protein needs, based on height, gender and frame size:
 http://www.healthcalculators.org/calculators/protein.asp
( This test is based on information available through the American Dietetics Association. )
2. Divide number of your protein grams on 24 (hours). Get an amount of what you need per hour. 
This way, roughly, you will know your hourly protein needs. Roughly, because they will still vary depending on your being sedentary, asleep, moving, exercising and so on. But you will know, approximately, how long your protein intake lasts.


What protein bar is comparable in taste and nutrition as Isagenix bars?


I really really love the Isagenix protein bars (chocolate crunch! YUM! Tastes like a candy bar!), but they are so expensive. Are there any other protein bars out there that any of you have found that taste very similar to the Isagenix bars? Any that taste like them and have similar amounts of protein?
I just don't want to have to go out and spend tons of money on trying out new bars to see which one is the most similar if someone else has already found out which one is best!!


Thank you!
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I don't know about your bar, but i eat a nanotechnology gel that has 10 Grs. of Milk Serum Protein, this gel has a nice flavor of chocolate truffle or strawberry banana. This technology allows to put a bigger amount of protein in a smaller space.

This gel is the same tio eat a can of tuna fish. I train parkour and this boosts energy very well.

Should you want to know more about this product just contact me, i dont sell it but i can tell you how to get it in your country is easy and not too expensive.


How much protein should I take daily even if I am taking creatine?


What happens if I take too much protein, recommended for people trying to bulk up is 1-1.5grams of protein per pound of bodyweight. So if I am trying to gain a lot of muscle and am using creatine to help become bulker would I still be needing to eat 140g of protein a day (I weigh about 140 Lbs.)? Or would I just be needing regular 60g because I don't know if there is an effect with the protein and creatine.
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Hey Bro,
I'm not sure how you are taking your protein,but a couple of things to think about. Take it within 30 min of your workout for best results and absorption into your body and muscles. You may also need to spread out your quantity of protein, as the body absorbs about 20 grams at a time, if you do 60 all at once you are probably crapping some of it out.
I take a shake with 20 grams, twice a day.
The guys I get my protein from is below; they have a forum page with some great workout discussions and some good recipes for smoothies.
the choc flavor is the best.
Also attached a piece on creatine.
Good luck.


Can protein powder be added to quick bread mixes?


I have added protein powder in the past to brownie mixes.  Although a bit dry, it is still good.  I am wondering if the same can be done with a quick bread mix (Pilsbury Pumpkin Quick Bread).  If so how much?
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Yes it can. How much depends on the particular protein powder. Check the manufacturer's website.


How much protein is in the average protein drink compared to milk?


I was wondering how much more protein is in the average protein drink compared to a glass of milk.  Also, I was hoping for protein mix suggestions for a beginner user of supplements and where you can purchase the mix.  Thanks.
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whether it's a pre-made drink or protein powder, there's usually about 20-30g per serving. personally, i'd go for the whey powder because it gives you the freedom to mix ingredients yourself. buy yourself a good blender and mix it up with fat free milk, yogurt, flax seeds, and fruits. you can get them for pretty cheap if you look at wal-mart or sam's club. try those out to get used to the taste and texture before looking for an expensive brand name.


What kind of protein could a 14 year old boy drink to gain weight fast?


What kind of protein milk/shake could I drink to get fatter? Im 14 year old boy and my weight is 120. Everytime I eat, I became 121-123. Then after a hour I became 120 again.. Awhile ago I drunk a Whey Protein then eat then I became 124-125 but after a hour again I became 120 again.:( My dad said I can only drink Whey protein once per day and it doesnt help alot.. What kind of protein milk or shake does taste good and can drink anytime I want? What kind of protein milk or shake does make me fatter fast?
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Get off empty calorie junk food & sugary sweet soda's. Start eating a good, healthy, balanced diet. Drink plenty of water & milk Snack on lots of raw fruits & vegetables. Fix yourself a milkshake every day & add (1) raw egg into the blender. You cannot see nor taste the egg once it is blended. It will add extra protein. Get up one hour early every morning & take a BRISK 30 minute walk - then - do the same thing again in the evening after dinner. If you can't gain weight with fat - you can gain weight in muscle. You should start filling out as puberty progresses also.