Genetic Engineering: Directed modification of the gene complement of a living organism by such techniques as altering the DNA, substituting genetic material by means of a virus, transplanting whole nuclei, transplanting cell hybrids, etc.Protein Engineering: Procedures by which protein structure and function are changed or created in vitro by altering existing or synthesizing new structural genes that direct the synthesis of proteins with sought-after properties. Such procedures may include the design of MOLECULAR MODELS of proteins using COMPUTER GRAPHICS or other molecular modeling techniques; site-specific mutagenesis (MUTAGENESIS, SITE-SPECIFIC) of existing genes; and DIRECTED MOLECULAR EVOLUTION techniques to create new genes.Tissue Engineering: Generating tissue in vitro for clinical applications, such as replacing wounded tissues or impaired organs. The use of TISSUE SCAFFOLDING enables the generation of complex multi-layered tissues and tissue structures.Metabolic Engineering: Methods and techniques used to genetically modify cells' biosynthetic product output and develop conditions for growing the cells as BIOREACTORS.Biotechnology: Body of knowledge related to the use of organisms, cells or cell-derived constituents for the purpose of developing products which are technically, scientifically and clinically useful. Alteration of biologic function at the molecular level (i.e., GENETIC ENGINEERING) is a central focus; laboratory methods used include TRANSFECTION and CLONING technologies, sequence and structure analysis algorithms, computer databases, and gene and protein structure function analysis and prediction.Plants, Genetically Modified: PLANTS, or their progeny, whose GENOME has been altered by GENETIC ENGINEERING.Biomedical Engineering: Application of principles and practices of engineering science to biomedical research and health care.Theology: The study of religion and religious belief, or a particular system or school of religious beliefs and teachings (from online Cambridge Dictionary of American English, 2000 and WordNet: An Electronic Lexical Database, 1997)Genetic Vectors: DNA molecules capable of autonomous replication within a host cell and into which other DNA sequences can be inserted and thus amplified. Many are derived from PLASMIDS; BACTERIOPHAGES; or VIRUSES. They are used for transporting foreign genes into recipient cells. Genetic vectors possess a functional replicator site and contain GENETIC MARKERS to facilitate their selective recognition.Transformation, Genetic: Change brought about to an organisms genetic composition by unidirectional transfer (TRANSFECTION; TRANSDUCTION, GENETIC; CONJUGATION, GENETIC, etc.) and incorporation of foreign DNA into prokaryotic or eukaryotic cells by recombination of part or all of that DNA into the cell's genome.Crops, Agricultural: Cultivated plants or agricultural produce such as grain, vegetables, or fruit. (From American Heritage Dictionary, 1982)Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Biofuels: Hydrocarbon-rich byproducts from the non-fossilized BIOMASS that are combusted to generate energy as opposed to fossilized hydrocarbon deposits (FOSSIL FUELS).Tissue Scaffolds: Cell growth support structures composed of BIOCOMPATIBLE MATERIALS. They are specially designed solid support matrices for cell attachment in TISSUE ENGINEERING and GUIDED TISSUE REGENERATION uses.Erabutoxins: Toxins isolated from the venom of Laticauda semifasciata, a sea snake (Hydrophid); immunogenic, basic polypeptides of 62 amino acids, folded by four disulfide bonds, block neuromuscular end-plates irreversibly, thus causing paralysis and severe muscle damage; they are similar to Elapid neurotoxins.Genetic Enhancement: The use of genetic methodologies to improve functional capacities of an organism rather than to treat disease.Betalains: Compounds derived from TYROSINE via betalamic acid, including BETAXANTHINS and BETACYANINS. They are found in the Caryophyllales order of PLANTS and some BASIDIOMYCETES.Gene Transfer Techniques: The introduction of functional (usually cloned) GENES into cells. A variety of techniques and naturally occurring processes are used for the gene transfer such as cell hybridization, LIPOSOMES or microcell-mediated gene transfer, ELECTROPORATION, chromosome-mediated gene transfer, TRANSFECTION, and GENETIC TRANSDUCTION. Gene transfer may result in genetically transformed cells and individual organisms.Escherichia coli: A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.Gene Targeting: The integration of exogenous DNA into the genome of an organism at sites where its expression can be suitably controlled. This integration occurs as a result of homologous recombination.Transgenes: Genes that are introduced into an organism using GENE TRANSFER TECHNIQUES.Biocompatible Materials: Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Plasmids: Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS.Recombinant Proteins: Proteins prepared by recombinant DNA technology.Plant Proteins: Proteins found in plants (flowers, herbs, shrubs, trees, etc.). The concept does not include proteins found in vegetables for which VEGETABLE PROTEINS is available.Recombinant Fusion Proteins: Recombinant proteins produced by the GENETIC TRANSLATION of fused genes formed by the combination of NUCLEIC ACID REGULATORY SEQUENCES of one or more genes with the protein coding sequences of one or more genes.Bioengineering: The application of engineering principles and methods to living organisms or biological systems.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.XyloseFermentation: Anaerobic degradation of GLUCOSE or other organic nutrients to gain energy in the form of ATP. End products vary depending on organisms, substrates, and enzymatic pathways. Common fermentation products include ETHANOL and LACTIC ACID.Cell Engineering: Methods and techniques used to modify or select cells and develop conditions for growing cells for biosynthetic production of molecules (METABOLIC ENGINEERING), for generation of tissue structures and organs in vitro (TISSUE ENGINEERING), or for other BIOENGINEERING research objectives.Metabolic Networks and Pathways: Complex sets of enzymatic reactions connected to each other via their product and substrate metabolites.Cloning, Molecular: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.Agrobacterium tumefaciens: A species of gram-negative, aerobic bacteria isolated from soil and the stems, leafs, and roots of plants. Some biotypes are pathogenic and cause the formation of PLANT TUMORS in a wide variety of higher plants. The species is a major research tool in biotechnology.Chemical EngineeringPlastids: Self-replicating cytoplasmic organelles of plant and algal cells that contain pigments and may synthesize and accumulate various substances. PLASTID GENOMES are used in phylogenetic studies.Streptomyces: A genus of bacteria that form a nonfragmented aerial mycelium. Many species have been identified with some being pathogenic. This genus is responsible for producing a majority of the ANTI-BACTERIAL AGENTS of practical value.Tobacco: A plant genus of the family SOLANACEAE. Members contain NICOTINE and other biologically active chemicals; its dried leaves are used for SMOKING.Pest Control, Biological: Use of naturally-occuring or genetically-engineered organisms to reduce or eliminate populations of pests.Recombination, Genetic: Production of new arrangements of DNA by various mechanisms such as assortment and segregation, CROSSING OVER; GENE CONVERSION; GENETIC TRANSFORMATION; GENETIC CONJUGATION; GENETIC TRANSDUCTION; or mixed infection of viruses.Pyruvate Decarboxylase: Catalyzes the decarboxylation of an alpha keto acid to an aldehyde and carbon dioxide. Thiamine pyrophosphate is an essential cofactor. In lower organisms, which ferment glucose to ethanol and carbon dioxide, the enzyme irreversibly decarboxylates pyruvate to acetaldehyde. EC 4.1.1.1.Integrases: Recombinases that insert exogenous DNA into the host genome. Examples include proteins encoded by the POL GENE of RETROVIRIDAE and also by temperate BACTERIOPHAGES, the best known being BACTERIOPHAGE LAMBDA.Bacterial Proteins: Proteins found in any species of bacterium.Gene Expression Regulation, Plant: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in plants.Droughts: Prolonged dry periods in natural climate cycle. They are slow-onset phenomena caused by rainfall deficit combined with other predisposing factors.Genetic Therapy: Techniques and strategies which include the use of coding sequences and other conventional or radical means to transform or modify cells for the purpose of treating or reversing disease conditions.Lignin: The most abundant natural aromatic organic polymer found in all vascular plants. Lignin together with cellulose and hemicellulose are the major cell wall components of the fibers of all wood and grass species. Lignin is composed of coniferyl, p-coumaryl, and sinapyl alcohols in varying ratios in different plant species. (From Merck Index, 11th ed)Plants: Multicellular, eukaryotic life forms of kingdom Plantae (sensu lato), comprising the VIRIDIPLANTAE; RHODOPHYTA; and GLAUCOPHYTA; all of which acquired chloroplasts by direct endosymbiosis of CYANOBACTERIA. They are characterized by a mainly photosynthetic mode of nutrition; essentially unlimited growth at localized regions of cell divisions (MERISTEMS); cellulose within cells providing rigidity; the absence of organs of locomotion; absence of nervous and sensory systems; and an alternation of haploid and diploid generations.Genes, Plant: The functional hereditary units of PLANTS.Animals, Genetically Modified: ANIMALS whose GENOME has been altered by GENETIC ENGINEERING, or their offspring.Gene Expression: The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.Transduction, Genetic: The transfer of bacterial DNA by phages from an infected bacterium to another bacterium. This also refers to the transfer of genes into eukaryotic cells by viruses. This naturally occurring process is routinely employed as a GENE TRANSFER TECHNIQUE.Models, Molecular: Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.Bioartificial Organs: Artificial organs that are composites of biomaterials and cells. The biomaterial can act as a membrane (container) as in BIOARTIFICIAL LIVER or a scaffold as in bioartificial skin.Chromosomes, Artificial, Bacterial: DNA constructs that are composed of, at least, a REPLICATION ORIGIN, for successful replication, propagation to and maintenance as an extra chromosome in bacteria. In addition, they can carry large amounts (about 200 kilobases) of other sequence for a variety of bioengineering purposes.Antigens, Plant: Substances found in PLANTS that have antigenic activity.Multigene Family: A set of genes descended by duplication and variation from some ancestral gene. Such genes may be clustered together on the same chromosome or dispersed on different chromosomes. Examples of multigene families include those that encode the hemoglobins, immunoglobulins, histocompatibility antigens, actins, tubulins, keratins, collagens, heat shock proteins, salivary glue proteins, chorion proteins, cuticle proteins, yolk proteins, and phaseolins, as well as histones, ribosomal RNA, and transfer RNA genes. The latter three are examples of reiterated genes, where hundreds of identical genes are present in a tandem array. (King & Stanfield, A Dictionary of Genetics, 4th ed)Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Mutagenesis: Process of generating a genetic MUTATION. It may occur spontaneously or be induced by MUTAGENS.Mutagenesis, Site-Directed: Genetically engineered MUTAGENESIS at a specific site in the DNA molecule that introduces a base substitution, or an insertion or deletion.Seeds: The encapsulated embryos of flowering plants. They are used as is or for animal feed because of the high content of concentrated nutrients like starches, proteins, and fats. Rapeseed, cottonseed, and sunflower seed are also produced for the oils (fats) they yield.Sequence Analysis, DNA: A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.Hydrogels: Water swollen, rigid, 3-dimensional network of cross-linked, hydrophilic macromolecules, 20-95% water. They are used in paints, printing inks, foodstuffs, pharmaceuticals, and cosmetics. (Grant & Hackh's Chemical Dictionary, 5th ed)Synthetic Biology: A field of biological research combining engineering in the formulation, design, and building (synthesis) of novel biological structures, functions, and systems.Oryza sativa: Annual cereal grass of the family POACEAE and its edible starchy grain, rice, which is the staple food of roughly one-half of the world's population.Models, Biological: Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.Porosity: Condition of having pores or open spaces. This often refers to bones, bone implants, or bone cements, but can refer to the porous state of any solid substance.Rhizobium: A genus of gram-negative, aerobic, rod-shaped bacteria that activate PLANT ROOT NODULATION in leguminous plants. Members of this genus are nitrogen-fixing and common soil inhabitants.Photosynthesis: The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide using energy obtained from light rather than from the oxidation of chemical compounds. Photosynthesis comprises two separate processes: the light reactions and the dark reactions. In higher plants; GREEN ALGAE; and CYANOBACTERIA; NADPH and ATP formed by the light reactions drive the dark reactions which result in the fixation of carbon dioxide. (from Oxford Dictionary of Biochemistry and Molecular Biology, 2001)Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Cell Differentiation: Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.Molecular Structure: The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.DNA: A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).Biodegradation, Environmental: Elimination of ENVIRONMENTAL POLLUTANTS; PESTICIDES and other waste using living organisms, usually involving intervention of environmental or sanitation engineers.Regenerative Medicine: A field of medicine concerned with developing and using strategies aimed at repair or replacement of damaged, diseased, or metabolically deficient organs, tissues, and cells via TISSUE ENGINEERING; CELL TRANSPLANTATION; and ARTIFICIAL ORGANS and BIOARTIFICIAL ORGANS and tissues.Materials Testing: The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility.Bioreactors: Tools or devices for generating products using the synthetic or chemical conversion capacity of a biological system. They can be classical fermentors, cell culture perfusion systems, or enzyme bioreactors. For production of proteins or enzymes, recombinant microorganisms such as bacteria, mammalian cells, or insect or plant cells are usually chosen.Genes, Bacterial: The functional hereditary units of BACTERIA.Zinc Fingers: Motifs in DNA- and RNA-binding proteins whose amino acids are folded into a single structural unit around a zinc atom. In the classic zinc finger, one zinc atom is bound to two cysteines and two histidines. In between the cysteines and histidines are 12 residues which form a DNA binding fingertip. By variations in the composition of the sequences in the fingertip and the number and spacing of tandem repeats of the motif, zinc fingers can form a large number of different sequence specific binding sites.Gene Deletion: A genetic rearrangement through loss of segments of DNA or RNA, bringing sequences which are normally separated into close proximity. This deletion may be detected using cytogenetic techniques and can also be inferred from the phenotype, indicating a deletion at one specific locus.Polyesters: Polymers of organic acids and alcohols, with ester linkages--usually polyethylene terephthalate; can be cured into hard plastic, films or tapes, or fibers which can be woven into fabrics, meshes or velours.Pollen: The fertilizing element of plants that contains the male GAMETOPHYTES.DNA, Plant: Deoxyribonucleic acid that makes up the genetic material of plants.Agriculture: The science, art or practice of cultivating soil, producing crops, and raising livestock.Phylogeny: The relationships of groups of organisms as reflected by their genetic makeup.DNA Primers: Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.Kinetics: The rate dynamics in chemical or physical systems.Plant Diseases: Diseases of plants.Arabidopsis: A plant genus of the family BRASSICACEAE that contains ARABIDOPSIS PROTEINS and MADS DOMAIN PROTEINS. The species A. thaliana is used for experiments in classical plant genetics as well as molecular genetic studies in plant physiology, biochemistry, and development.Biomimetic Materials: Materials fabricated by BIOMIMETICS techniques, i.e., based on natural processes found in biological systems.Genome: The genetic complement of an organism, including all of its GENES, as represented in its DNA, or in some cases, its RNA.Embryonic Stem Cells: Cells derived from the BLASTOCYST INNER CELL MASS which forms before implantation in the uterine wall. They retain the ability to divide, proliferate and provide progenitor cells that can differentiate into specialized cells.Cyanobacteria: A phylum of oxygenic photosynthetic bacteria comprised of unicellular to multicellular bacteria possessing CHLOROPHYLL a and carrying out oxygenic PHOTOSYNTHESIS. Cyanobacteria are the only known organisms capable of fixing both CARBON DIOXIDE (in the presence of light) and NITROGEN. Cell morphology can include nitrogen-fixing heterocysts and/or resting cells called akinetes. Formerly called blue-green algae, cyanobacteria were traditionally treated as ALGAE.Promoter Regions, Genetic: DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.Sequence Alignment: The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.DNA, Bacterial: Deoxyribonucleic acid that makes up the genetic material of bacteria.Luminescent Proteins: Proteins which are involved in the phenomenon of light emission in living systems. Included are the "enzymatic" and "non-enzymatic" types of system with or without the presence of oxygen or co-factors.Genome, Plant: The genetic complement of a plant (PLANTS) as represented in its DNA.Nanofibers: Submicron-sized fibers with diameters typically between 50 and 500 nanometers. The very small dimension of these fibers can generate a high surface area to volume ratio, which makes them potential candidates for various biomedical and other applications.Models, Genetic: Theoretical representations that simulate the behavior or activity of genetic processes or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.Saccharomyces cerevisiae: A species of the genus SACCHAROMYCES, family Saccharomycetaceae, order Saccharomycetales, known as "baker's" or "brewer's" yeast. The dried form is used as a dietary supplement.Plant Leaves: Expanded structures, usually green, of vascular plants, characteristically consisting of a bladelike expansion attached to a stem, and functioning as the principal organ of photosynthesis and transpiration. (American Heritage Dictionary, 2d ed)Cell Line: Established cell cultures that have the potential to propagate indefinitely.Stress, Physiological: The unfavorable effect of environmental factors (stressors) on the physiological functions of an organism. Prolonged unresolved physiological stress can affect HOMEOSTASIS of the organism, and may lead to damaging or pathological conditions.Mice, Transgenic: Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.Guided Tissue Regeneration: Procedures for enhancing and directing tissue repair and renewal processes, such as BONE REGENERATION; NERVE REGENERATION; etc. They involve surgically implanting growth conducive tracks or conduits (TISSUE SCAFFOLDING) at the damaged site to stimulate and control the location of cell repopulation. The tracks or conduits are made from synthetic and/or natural materials and may include support cells and induction factors for CELL GROWTH PROCESSES; or CELL MIGRATION.Transfection: The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.Chloroplasts: Plant cell inclusion bodies that contain the photosynthetic pigment CHLOROPHYLL, which is associated with the membrane of THYLAKOIDS. Chloroplasts occur in cells of leaves and young stems of plants. They are also found in some forms of PHYTOPLANKTON such as HAPTOPHYTA; DINOFLAGELLATES; DIATOMS; and CRYPTOPHYTA.Genes, Reporter: Genes whose expression is easily detectable and therefore used to study promoter activity at many positions in a target genome. In recombinant DNA technology, these genes may be attached to a promoter region of interest.Mutagenesis, Insertional: Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt GENETIC TRANSLATION of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation.Protein Conformation: The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).Bone Regeneration: Renewal or repair of lost bone tissue. It excludes BONY CALLUS formed after BONE FRACTURES but not yet replaced by hard bone.Binding Sites: The parts of a macromolecule that directly participate in its specific combination with another molecule.Polymers: Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).Protein Structure, Tertiary: The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.Cell Culture Techniques: Methods for maintaining or growing CELLS in vitro.Green Fluorescent Proteins: Protein analogs and derivatives of the Aequorea victoria green fluorescent protein that emit light (FLUORESCENCE) when excited with ULTRAVIOLET RAYS. They are used in REPORTER GENES in doing GENETIC TECHNIQUES. Numerous mutants have been made to emit other colors or be sensitive to pH.Plant Roots: The usually underground portions of a plant that serve as support, store food, and through which water and mineral nutrients enter the plant. (From American Heritage Dictionary, 1982; Concise Dictionary of Biology, 1990)Polymerase Chain Reaction: In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.Proteins: Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.Retroviridae: Family of RNA viruses that infects birds and mammals and encodes the enzyme reverse transcriptase. The family contains seven genera: DELTARETROVIRUS; LENTIVIRUS; RETROVIRUSES TYPE B, MAMMALIAN; ALPHARETROVIRUS; GAMMARETROVIRUS; RETROVIRUSES TYPE D; and SPUMAVIRUS. A key feature of retrovirus biology is the synthesis of a DNA copy of the genome which is integrated into cellular DNA. After integration it is sometimes not expressed but maintained in a latent state (PROVIRUSES).Genomics: The systematic study of the complete DNA sequences (GENOME) of organisms.Decanoates: Salts and esters of the 10-carbon monocarboxylic acid-decanoic acid.Hydrogel: A network of cross-linked hydrophilic macromolecules used in biomedical applications.Biomimetics: An interdisciplinary field in materials science, ENGINEERING, and BIOLOGY, studying the use of biological principles for synthesis or fabrication of BIOMIMETIC MATERIALS.Triticum: A plant genus of the family POACEAE that is the source of EDIBLE GRAIN. A hybrid with rye (SECALE CEREALE) is called TRITICALE. The seed is ground into FLOUR and used to make BREAD, and is the source of WHEAT GERM AGGLUTININS.Directed Molecular Evolution: The techniques used to produce molecules exhibiting properties that conform to the demands of the experimenter. These techniques combine methods of generating structural changes with methods of selection. They are also used to examine proposed mechanisms of evolution under in vitro selection conditions.Gene Expression Regulation, Bacterial: Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in bacteria.Water: A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Mesenchymal Stromal Cells: Bone-marrow-derived, non-hematopoietic cells that support HEMATOPOETIC STEM CELLS. They have also been isolated from other organs and tissues such as UMBILICAL CORD BLOOD, umbilical vein subendothelium, and WHARTON JELLY. These cells are considered to be a source of multipotent stem cells because they include subpopulations of mesenchymal stem cells.Antibodies, Monoclonal: Antibodies produced by a single clone of cells.DNA Transposable Elements: Discrete segments of DNA which can excise and reintegrate to another site in the genome. Most are inactive, i.e., have not been found to exist outside the integrated state. DNA transposable elements include bacterial IS (insertion sequence) elements, Tn elements, the maize controlling elements Ac and Ds, Drosophila P, gypsy, and pogo elements, the human Tigger elements and the Tc and mariner elements which are found throughout the animal kingdom.Absorbable Implants: Implants constructed of materials designed to be absorbed by the body without producing an immune response. They are usually composed of plastics and are frequently used in orthopedics and orthodontics.Bacteria: One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.Sequence Homology, Amino Acid: The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.Nanostructures: Materials which have structured components with at least one dimension in the range of 1 to 100 nanometers. These include NANOCOMPOSITES; NANOPARTICLES; NANOTUBES; and NANOWIRES.Silk: A continuous protein fiber consisting primarily of FIBROINS. It is synthesized by a variety of INSECTS and ARACHNIDS.

*  Genetic engineering | Define Genetic engineering at Dictionary.com
Genetic engineering. Define Genetic engineering at ... Google+ Share. genetic engineering. Examples. Word Origin. ... noun , Genetics. 1 the development and application of ... Genetic engineering. Define Genetic engineering at Dictionary.com. Dictionary.com. Word of the Day Translate Games Blog. Thesaurus.com Apps. follow Dictionary.com. Dictionary.com. Try Our Apps. Word of the Day. follow Dictionary.com. CITE. genetic engineering. Word Origin. noun, Genetics. 2 a technique that produces unlimited amounts of otherwise unavailable or scarce biological product by introducing DNA isolated from animals or plants into bacteria and then harvesting the product from a bacterial colony, as human insulin produced in bacteria by the human insulin gene. Expand. Origin of genetic engineering Expand. genetic engineer, noun. Dictionary.com Unabridged Based on the Random House Dictionary, © Random House, Inc. Cite This Source. Examples from the Web for genetic engineering Expand. British Dictionary definitions for...
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*  Get Monsanto Off Your Lawn! · Causes
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*  Next Big Future: Sources of longevity genes for genetic engineering
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*  Genetic Engineering...
Genetic Engineering. ... Genetic Engineering. ... report on Genetic Engineering. However, I need to report on a more ... to the use of genetic engineering, other than obtaining ... genetic engineering genetic engineering benjamin hiu tung lai bennyboy at suburbia net sun jul est previous message recombination rate next message recombination rate messages sorted by hi i am cureently doing an investigation report on genetic engineering however i need to report on a more specific topic application i am just curious what are some of the examples applications relating to the use of genetic engineering other than obtaining pharmaceutical proteins from transgenic animals regards beni previous message recombination rate next message recombination rate messages sorted by more information about the gen link mailing list...
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*  IPBiz: US 8,993,303 to South Dakota State University: Genetically engineered cyanobacteria
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*  Tell the FDA to label genetically engineered foods! | EWG
the FDA to label genetically engineered foods. EWG. Skip to ... the FDA to label genetically engineered foods. Support Our Work ... the FDA to label genetically engineered foods. Tell the FDA to...
http://ewg.org/node/16021/related
*  Cuba Registers New Antibody ( Cuba's Center for Genetic Engineering a...)
Cuba Registers New Antibody Cuba's Center for Genetic Engineering a. ... Cuba's Center for Genetic Engineering and Biotechnology CIGB has ... Cuba's Center for Genetic Engineering and Biotechnology CIGB has ... Breaking Medicine Technology: Gaumard Scientific to Feature Comprehensive Line-Up of Innovative Patient Simulators for Health Care Education at the FIGO World Congress 2015 2 Gaumard Scientific to Feature Comprehensive Line-Up of Innovative Patient Simulators for Health Care Education at the FIGO World Congress 2015 3 Gaumard Scientific to Feature Comprehensive Line-Up of Innovative Patient Simulators for Health Care Education at the FIGO World Congress 2015 4 Gaumard Scientific to Feature Comprehensive Line-Up of Innovative Patient Simulators for Health Care Education at the FIGO World Congress 2015 5 Gaumard Scientific to Feature Comprehensive Line-Up of Innovative Patient Simulators for Health Care Education at the FIGO World Congress 2015 6 Gaumard Scientific to Feature Comprehensive Line-Up of ...
http://bio-medicine.org/medicine-news/Cuba-Registers-New-Antibody-11651-1/
*  PPT - Plant Tissue Culture Application PowerPoint Presentation - ID:1252623
fusion. Plant Genetic Engineering. Tissue Culture ... fusion. Plant genetic engineering. Has been used to eliminate...
http://slideserve.com/salena/plant-tissue-culture-application
*  TruthAlliance.net > News > Genetically Engineered Food Alters Our Digestive Systems!
net > News > Genetically Engineered Food Alters Our ... Digestive Systems. Genetically Engineered Food Alters Our ... clinical trials of genetically engineered foods. The only...
http://truthalliance.net/Archive/News/tabid/67/ID/7764/categoryId/5/Genetically-Engineered-Food-Alters-Our-Digestive-Systems.aspx
*  .. Genetically modified foods invade U.S. diets .. Chuck Norris explains why it's not only matter o
Genetically modified foods invade U.S. Chuck ... in your email. Genetically modified crops constitute 93 ... tests prove that genetically engineered organisms become a part...
http://wnd.com/2011/06/312309/
*  Chromosome engineering
'Chromosome engineering' is "the controlled generation of chromosomal deletions, inversions, or translocations with defined endpoints.". 2 By combining chromosomal translocation, chromosomal inversion,and chromosomal deletion, chromosome engineering has been shown to identify the underlying genes that cause certain diseases in mice. In coming years, it is very likely that chromosomal engineering will be able to do the same identification for diseases in humans, as well as all other organisms. 3 The Three Types of Chromosome Engineering Experiments of Chromosome Engineering See also References. The Three Types of Chromosome Engineering. chromosomal deletion. chromosomal inversion. chromosomal translocation. Chromosomal deletion is a mutation a genetic aberration in which a part of a chromosome or a sequence of DNA is missing. Chromosomal translocation is a chromosome abnormality caused by rearrangement of parts between nonhomologous chromosomes. Experiments of Chromosome Engineering. In an experiment pertainin...
https://en.wikipedia.org/wiki/Chromosome_engineering
*  No Sure Fix: Prospects for Reducing Nitrogen Fertilizer Pollution through Genetic Engineering (2009)
No Sure Fix: Prospects for Reducing Nitrogen Fertilizer Pollution through Genetic Engineering 2009. Skip to main content Union of Concerned Scientists. Clean Energy. Clean Vehicles. Food Agriculture. Global Warming. Nuclear Power. Nuclear Weapons. Center for Science and Democracy. Accomplishments History. Leadership Experts. Funding Financials. Take Action. You are here Food Agriculture. Genetic Engineering in Agriculture. No Sure Fix: Prospects for Reducing Nitrogen Fertilizer Pollution through Genetic Engineering 2009. Crops genetically engineered to use nitrogen more efficiently—a trait that can help increase yields while reducing pollution—have proved disappointing so far. Much of the excess nitrogen escapes from the farm and becomes a major component of global pollution, contributing to global warming, acid rain, and “dead zones” in the ocean. Genetic engineering GE that would enable crops to use nitrogen more efficiently has been proposed as a way of reducing nitrogen pollution while maintaining or incr...
http://ucsusa.org/food_and_agriculture/our-failing-food-system/genetic-engineering/no-sure-fix.html
*  International Vegetarian Union - Genetic Engineering
... International Vegetarian Union IVU. Genetic Engineering Inginerie genetica - Genteknik Espa ol - Alimentos transg nicos: un riesgo serio para la salud UVA. Espa ol - Alimentaci n modificada gen ticamente UVA. . Food biotechnology: the art of moulding life to suit contingent economic requirements European Congress 1997. . Genetically Engineered Foods in Canada TVA 1997. . Genetically manipulated foods European Congress 1997. Espa ol - Alimentos manipulados gen ticamente. Genetic Engineering VeganSoc Genetic Engineering - from 'Doctors for the Protection of the Environment' Switzerland EVU News, 1997. Deutsch - Gentechnologie - Aerztinnen und Aerzte f r Umweltschutz. Italiano - Ingegneria Genetica - Dottori per la Protezione dell'Ambiente. Genetic Engineering: an Extremely Costly Risk European Congress 1997 Genetic Engineering - can it be all that bad. Ask the animals. Deutsch - Genmanipulation - Kann es alles so schlecht sein. Frag' die Tiere. Espa ol - Ingenier a Gen tica - Puede ser tan mala. Preguntad ...
http://ivu.org/science/articles/genetic.html
*  International Vegetarian Union - Genetic Engineering
... International Vegetarian Union IVU. Genetic Engineering Inginerie genetica - Genteknik Espa ol - Alimentos transg nicos: un riesgo serio para la salud UVA. Espa ol - Alimentaci n modificada gen ticamente UVA. . Food biotechnology: the art of moulding life to suit contingent economic requirements European Congress 1997. . Genetically Engineered Foods in Canada TVA 1997. . Genetically manipulated foods European Congress 1997. Espa ol - Alimentos manipulados gen ticamente. Genetic Engineering VeganSoc Genetic Engineering - from 'Doctors for the Protection of the Environment' Switzerland EVU News, 1997. Deutsch - Gentechnologie - Aerztinnen und Aerzte f r Umweltschutz. Italiano - Ingegneria Genetica - Dottori per la Protezione dell'Ambiente. Genetic Engineering: an Extremely Costly Risk European Congress 1997 Genetic Engineering - can it be all that bad. Ask the animals. Deutsch - Genmanipulation - Kann es alles so schlecht sein. Frag' die Tiere. Espa ol - Ingenier a Gen tica - Puede ser tan mala. Preguntad ...
http://ivu.org/science/articles/genetic.html
*  Genetic Engineering...
genetic engineering genetic engineering graham dellaire popa at po box mcgill ca sun jul est previous message genetic engineering next message unsubscribe help messages sorted by bennyboy at suburbia net benjamin hiu tung lai writes hi i am cureently doing an investigation report on genetic engineering however i need to report on a more specific topic application i am just curious what are some of the examples applications relating to the use of genetic engineering other than obtaining pharmaceutical proteins from transgenic animals regards beni tomatoes they transfered a gene enzyme from a pig so that they would remain firm longer sorry can t remeber the details beyond that plants in general are light ahead in genetic engineering than animal studies g graham dellaire snail mail red cross research mcgill university montreal blood services faculty of medicine sherbrooke st east div of experimental medicine montreal qc canada e mail popa at po box mcgill ca h w b b xe at musicb mcgill ca www page http www medco...
http://bio.net/bionet/mm/biochrom/1995-July/000705.html
*  First Year - Genetic Engineering and Biotechnology | DU
First Year - Genetic Engineering and Biotechnology. GEB 101: Basic Biology 1. 2 Ionic bonds general characteristics, types of ions; Covalent bond general characteristics ; Coordiante covalent bond; Valence bond approach; Sigma and Pi bonds; Bond length; Bond order; Hydrogen bonds; Van der Wall’s forces; Metallic bond; Concept of coordination complexes; Werner’s theory; Bonding in coordination compounds; Role of inorganic elements in some vital complexes of biological importance e.g. Chemical bonding reconsidered: Atomic and molecular orbitals; Polarity of bonds; Bond length and bond strength; Bond energy; bond moment and dipole moment; Nucleophiles and electrophiles and their importance in biological systems; Characteristics and type of organic reactions: Addition, elimination, substitution and rearrangement reactions. Suggested readings: 1. A General Chemistry, W.H. GEB 103: Basic Biochemistry 1. Suggested readings: 1. Biochemistry., M/s Worth Publishers Inc,, New York 2. 1 Biotechnology Definition; History ...
http://gebudhaka.net/geb/index.php/2012-01-11-12-25-01/first-year
*  Genetic engineering is a Good Thing?
Genetic engineering is a Good Thing. Genetic engineering is a Good Thing. Oz Oz at upthorpe.demon.co.uk. Thu Sep 17 00:09:03 EST 1998. Previous message: Genetic engineering is a Good Thing. Next message: Genetic engineering is a Good Thing. Messages sorted by:. In article taquilla.1256383902E at news.erols.com, Tracy Aquilla taquilla at erols.com writes It is really only a question of public image at this point, and the drugs seem to have no problem in this area. For some reason, most of the opposition to the technology seems to focus on the agricultural applications. I can't help getting the feeling that those wishing to attack technology have come to the conclusion that reads, some what paraphrased, One can do without food, but not without drugs. People will accept almost anything when it comes to intervention to give a few years extra life to a developed world person, but are suspicious of any small attempt to grow more food using the most benign products. Indeed healthy people will consume quantities of t...
http://bio.net/bionet/mm/bioforum/1998-September/027208.html
*  Attitudes to life extension via genetic engineering
... rick abrams ricka at praline no neosoft com mon feb est previous message attitudes to life extension via genetic engineering next message attitudes to life extension via genetic engineering messages sorted by in article pine sol a at corona patrick o neil patrick at corona wrote on feb rick abrams wrote please define natural life span is it the years of the woman in france or my father s who died two years younger than i am today heart failure there is no set hard span but i have read estimates that put maximum human lifespan at around years which doesn t bode all too well for the frenchwoman depending on how one views things if i were a betting man i would bet against the woman getting to the max possible is barring other factors such as cancer heart disease alzheimer s congenital defects etc unfortunately for your father disease got him rather than age related degeneration think it through why is a natural death but not all i see is you saying is words mean what ever i want them to mean rha previous me...
http://bio.net/bionet/mm/ageing/1995-February/001335.html
*  Model Engineering and engineering tools online from RDG Tools Ltd Home Page (Engineering Tools) Tel
Model Engineering and engineering tools online from RDG Tools Ltd Home Page Engineering Tools Tel 01422 885069 /884605. Home current. Exhibitions. Contact Us. Toggle navigation. Info. Home current. Info Exhibitions. Search. Contact Us. Items:. Value:. Basket Checkout. Items:. Value:. Basket. Checkout. Product Sections. View Product Sections Airbrushes and Compressors Abrasive & Sanding Pads & Grinding wheels Acme Taps and Dies Air Tools. Angle Plates. Boring Bars. Broaches ( Keyway Broaches ,High Speed Steel ) Boring Heads and Shanks Boxford / Viceroy Lathe Users Page Books. BCA Jig borer tools Carbide burrs Coolant Products and Oils Compound Tables Colchester Bantam Gears. Centres / Morse Taper dead / Half Dead Collet Chucks and Collets Clamping kits and Clamping Tools Centre Drills (Sets and Individual) Carbide Inserts for Lathes and Milling Machines Counterbores Countersinks / Step Drills Colchester Lathe Parts and Accessories Drip Feed Oilers Dovetail Cutters Do...
http://rdgtools.co.uk/cgi-bin/ss000001.pl?PRODREF=29&NOLOGIN=1
*  Amateurs are trying genetic engineering at home garages - Taipei Times
... ‧ World News. Front Page. Taiwan News. Business. Editorials. Sports. World News. Features. Bilingual Pages. Home / World News. Print. Facebook. Twitter. plurk. Amateurs are trying genetic engineering at home garages. AP, SAN FRANCISCO. Using homemade lab equipment and the wealth of scientific knowledge available online, these hobbyists are trying to create new life forms through genetic engineering — a field long dominated by PhDs toiling in university and corporate laboratories. In her San Francisco dining room lab, for example, 31-year-old computer programmer Meredith Patterson is trying to develop genetically altered yogurt bacteria that will glow green to signal the presence of melamine, the chemical that turned Chinese-made baby formula and pet food deadly. Many of these amateurs may have studied biology in college but have no advanced degrees and are not earning a living in the biotechnology field. Co-founder Mackenzie Cowell, a 24-year-old who majored in biology in college, said amateurs will prob...
http://taipeitimes.com/News/world/archives/2008/12/28/2003432247
*  Genetic engineering: Who knows where it will go | Hoards Dairyman
Genetic engineering: Who knows where it will go. Hoards Dairyman. Skip to Navigation. Genetic engineering: Who knows where it will go. Submitted by admin on Fri, 06/22/2012 - 10:12. Hoard s Dairyman: Genetic engineering: Who knows where it will go. Date: Fri, 06/22/2012. Chinese low-lactose calf is likely just the beginning of dairy applications. by Dennis Halladay, Hoard’s Dairyman Western Editor. Put on your Star Wars T-shirt; this is a subject where one’s imagination can run wild. Relatively speaking, genetic engineering is still in its infancy. Practical applications have begun to trickle out of labs, but “some day” is still a far more common status than “it’s here now.”. In terms of dairy applications, we’ve mapped the bovine genome and are already using a basic version of cloning, but there’s little in the sci-fi category. That just changed in China, however, where researchers announced earlier this month that they had produced a Holstein calf, born in April, that is genetically engineered to make milk ...
http://hoards.com/blog_genetic-engineering?mini=calendar%2F2013-01
*  .. Good and bad genetic engineering of foods .. Rate this:
Good and bad genetic engineering of foods. leave a comment ». A prominent good engineering IMO is golden rice. Two other examples of helpful genetic engineering are reported by Dan Cossins in The Scientist :. Two unsuspecting farm animals have helped to demonstrate the increasing accuracy of genetic engineering techniques. The first is a cow that produced hypoallergenic milk after researchers used RNA interference to block the production of an allergy-inducing protein, as reported this week October 2 in Proceedings of the National Academy of Sciences. The second, reported in another paper  in the same issue, is a pig that could be a model for atherosclerosis after researchers used an enzyme called a TALEN to silence a gene that helps to remove cholesterol. Researchers have long struggled to remove cow milk’s allergy-inducing protein, beta-lactoglobulin, which can cause diarrhea and vomiting in children. They were previously unable to introduce foreign genes precisely enough, however, so they could never ...
https://leisureguy.wordpress.com/2012/10/04/good-and-bad-genetic-engineering-of-foods/
*  Genetic Engineering And DNA Manipulation As The Biotechnology.. Stock Photo, Picture And Royalty Fre
... e Image. Image 18859851. Live Help. English. 45,747,722 ROYALTY FREE STOCK PHOTOS. Stock Photo - Genetic engineering and DNA manipulation as the biotechnology science of genetically modified foods or living organisms with an image of a dna strand on a parchment texture being changed by a pencil eraser. Genetic engineering and DNA manipulation as the biotechnology science of genetically modified foods or living organisms with an image of a dna strand on a parchment texture being changed by a pencil eraser. Share. Share. Twitter. Facebook. Google+. Pinterest. Image ID : 18859851. Image Type : Stock Photo. Standard License. Extended License. Additional Multi-seat License. Stock Photo Keywords. agricultural, biology, biotechnology, changing, chemical, cloning, close up, cure, deoxyribonucleic acid, dna, dna manipulation, dna strand, enzyme, eraser, erasing, experiments, future science, gene manipulation, gene sequencing, gene therapy, genes, genetic code, genetic engineering, genetic modification, genetically...
http://123rf.com/photo_18859851_genetic-engineering-and-dna-manipulation-as-the-biotechnology-science-of-genetically-modified-foods-.html
*  Biotechnology Glossary | USDA
Questions & Answers on Food from Genetically Engineered Plants - Food and Drug Administration Genetically Engineered Animals Animal Cloning Information USDA Investigation of Genetically Engineered GE Glyphosate-Resistant Wheat. Agricultural Biotechnology : A range of tools, including traditional breeding techniques, that alter living organisms, or parts of organisms, to make or modify products; improve plants or animals; or develop microorganisms for specific agricultural uses. Bt crops : Crops that are genetically engineered to carry a gene from the soil bacterium Bacillus thuringiensis Bt. Used to test for the presence of a particular genetically engineered organism. Genetic engineering : Manipulation of an organism's genes by introducing, eliminating or rearranging specific genes using the methods of modern molecular biology, particularly those techniques referred to as recombinant DNA techniques. Genetically engineered organism GEO : An organism produced through genetic engineering. Genetic modification :...
http://usda.gov/wps/portal/usda/usdahome?contentid=biotech_glossary.html&contentidonly=true
*  Genetic engineering in the United States
... Investigation of Human Health Effects Associated with Potential Exposure to Genetically Modified Corn: A Report to the U.S. 3 For a genetically modified organism to be approved for release it is assessed by the USDA, the FDA and the EPA. USDA evaluated the plants potential to become weeds, the FDA reviewed plants that could enter or alter the food supply and the EPA regulated the genetically modified plants with pesticide properties. The Biotechnology Regulatory Services program of the Animal and Plant Health Inspection Service APHIS agency within the USDA is concerned with protecting agriculture and the environment from potential pests under the Plant Protection Act of 2000 part of the Agriculture Risk Protection Act and the National Environmental Policy Act NEPA. The USDA is responsible for approving field trial s of GM plants under either the notification or permit procedures. 7 Most field trials are approved under the notification procedure. Four federal district court suits have been brought against...
https://en.wikipedia.org/wiki/Genetic_engineering_in_the_United_States
*  .. Search Results .. Concerned Oahu Citizens Demand that Monsanto Stop Poisoning Hawaii .. Report F
Tuesday, July 3rd, 2012. Tuesday, June 12th, 2012. Posted in Genetic Engineering. Posted in Agriculture, Genetic Engineering, International. Posted in Genetic Engineering, Labeling. Friday, January 13th, 2012. Department of Agriculture’s USDA decision to deregulate genetically engineered GE alfalfa was not unlawful, as has been charged by organic and environmental advocates, including Beyond Pesticides. Posted in Agriculture, Genetic Engineering, Litigation, Monsanto. Department of Agriculture USDA approved yet another genetically modified seed by Monsanto, a drought-tolerant variety of corn, MON87460. Posted in 2,4-D, Dow Chemical, Genetic Engineering, Monsanto. Posted in Genetic Engineering. Posted in Genetic Engineering, Glyphosate, Monsanto. Friday, September 23rd, 2011. Friday, September 9th, 2011. Beyond Pesticides, September 9, 2011 Despite rising concerns over the side effects of herbicide tolerant, genetically engineered GE crops, Dow AgroSciences has recently asked for approval of a new GE soybean...
http://beyondpesticides.org/dailynewsblog/index.php?s=deregulate&paged=2
*  Fusion protein
'Fusion proteins' or 'chimeric proteins' literally, made of parts from different sources are proteins created through the joining of two or more gene s that originally coded for separate proteins. Translation of this ' fusion gene ' results in a single or multiple polypeptides with functional properties derived from each of the original proteins. 'Chimeric mutant proteins' occur naturally when a complex mutation, such as a chromosomal translocation, tandem duplication, or retrotransposition creates a novel coding sequence containing parts of the coding sequences from two different genes. Functions Recombinant technology Chimeric protein drugs. Some fusion proteins combine whole peptides and therefore contains all functional domains of the original proteins. However, other fusion proteins, especially those that are naturally occurring, combine only portions of coding sequences and therefore do not maintain the original functions of the parental genes that formed them. Recombinant technology. A 'recombinant fus...
https://en.wikipedia.org/wiki/Fusion_protein
*  Genetic engineering biotechnology is inherently hazardous
The public were, however, only dimly aware of critics who deplored tampering with nature and scrambling the genetic code of species by introducing human genes into animals, and animal genes into vegetables. And, in any case, there is no essential difference between transgenic plants produced by the new biotechnology and those produced by conventional breeding methods. Genetic engineering bypasses conventional breeding by using the artificially constructed vectors to multiply copies of genes, and in many cases, to carry and smuggle genes into cells. In animals, vectors are constructed from retroviruses causing cancers and other diseases. The practitioners of genetic engineering biotechnology, the regulators and the critics alike, have all underestimated the risks involved, which are inherent to genetic engineering biotechnology, particularly as misguided by an outmoded and erroneous world-view that comes from bad science. In Austria, a record 1.2 million citizens, representing 20 per cent of the electorate, ha...
https://organicconsumers.org/old_articles/ge/unholya.html
*  Genetic Engineering: Human Disorders and Gene Therapy
... infoplease Atlas. Encyclopedia. Dictionary. Thesaurus. Day in History. Atlas. History. Fifty States. Atlas. History. People People. People Home. Business. Science. History Gov't History Gov't. History Gov't Home. World History. History. Science Health Science Health. Science Health Home. Health. Technology. Calendar Holidays Calendar Holidays. Calendar Holidays Home. Business Business. Business Home. Business. Genetic Engineering Human Disorders and Gene Therapy Genetic Engineering Introduction. DNA Technology Applications Human Disorders and Gene Therapy Human Genome Project. Legal and Ethical Considerations Genetic disorders are the harmful effects on an individual caused by inherited genetic diseases or mutations. There are many genetic disorders; however, two are common in today's population: hemophilia A and sickle-cell anemia. Hemophilia A is a recessive sex-linked genetic disorder that is exhibited by approximately 1 in every 10,000 Caucasian males. Sickle-cell anemia is a recessive genetic disord...
http://infoplease.com/cig/biology/human-disorders-gene-therapy.html
*  Dwarfing
Plants Dwarfing trees. Dwarfing grains. Any of these conditions can be established in a population through genetic engineering, selective breeding, or insular dwarfism, or some combination of the above. In some husbandry conditions, humans created dwarf breeds, or allowed them to develop, without specifically selecting for smaller animals. In the case of the Shetland sheep and collies, it is likely that environmental conditions, such as a lack of abundant fodder, led to farmers selecting smaller animals who continued to reproduce on limited food over larger animals who did not reproduce well on limited diets. Humans have encouraged the deliberate development of dwarf breeds of many domestic animals, including horses, cattle, dogs, and chickens. Even in breeds which have not been selected for dwarfing, some genetic lines may show a tendency to produce dwarfs, which may be encouraged by deliberate breeding. Rabbits American Fuzzy Lop, Britannia Petite US, Dwarf Hotot, Florida White Rabbit, Jersey Wooly, Lionhea...
https://en.wikipedia.org/wiki/Dwarfing
*  .. CAD Software .. Calculators .. Odds and Ends .. Productivity .. Engineering Tools Overload
Top 50 Free and Excellent Web Apps for Engineers. But, who can resist a model rocket simulator, even if you’re an electrical or Web engineer. This list of the top 50 free and excellent Web apps for engineers includes that app as well as tools for CAD, calculators and converters, productivity tools and entire online toolboxes that are all free to use. CAD Software. Calculators. Free Mechanical Engineering Online Calculators : This site carries a list of numerous calculators. Engineering Plastics Online Tools : Three calculators, including a snap-fit design calc, a cost calculator and a cycle time calculator. Shaft Speed Calculator : A three-in-one tool. See how fast end easy you can calculate speed having distance and time, how to find distance having time and speed and how to find time having speed and distance. Open Rocket : OpenRocket is an free, fully featured model rocket simulator that allows you to design and simulate your rockets before actually building and flying them. Trac Open Source Project : Trac...
http://onlineengineeringdegrees.org/top-50-free-and-excellent-web-apps-for-engineers/
*  Is Genetic Engineering the Answer to Hunger? - College Essay - 1748 Words
Genetically modified food, Genetic engineering, Genetically modified crops. Moreover, do we really need genetic modified food. Topics in this document Genetically modified food, Genetic engineering, Genetically modified crops, Plant breeding, Food security, Biotechnology, Agriculture, International Food Policy Research Institute, Famine, Malnutrition, Bacillus thuringiensis, Food, Food policy, Pesticide, Poverty, Allergy. {"essaysImgCdnUrl":"\/\/images-study.netdna-ssl.com\/pi\/","thumb default size":"160x220","thumb ac size":"80x110","isPayOrJoin":false,"essayUpload":false,"site id":1,"autoComplete":true,"logPixelPath":"\/\/www.smhpix.com\/pixel.gif","tracking url":"\/\/www.smhpix.com\/pixel.gif","essay":{"essayId":33890983,"categoryName":"Organizations","categoryParentId":"3","currentPage":1,"format":"text","pageMeta":{"text":{"startPage":1,"endPage":5,"pageRange":"1-5","totalPages":5}},"access":"premium","title":"Is Genetic Engineering the Answer to Hunger?","additionalIds":,"additional":,"loadedPages":{"h...
http://studymode.com/essays/Is-Genetic-Engineering-The-Answer-To-379021.html
*  Genetic engineering possibilities with Genus Radius/JS? - Jemsite
Genetic engineering possibilities with Genus Radius/JS. - Jemsite. Sponsor our community. Comparison Shopping Reviews Gallery Jemsite Blog Forums Home. Jemsite. Guitars and Gear. JS Satriani Model Ibanez Guitars. Genetic engineering possibilities with Genus Radius/JS. User Name. Remember Me. Password. Register. FAQ. Calendar iTrader Mark Forums Read. JS Satriani Model Ibanez Guitars Discussion about JS Joe Satriani Model Ibanez Guitars. Go to Page... Page 1 of 2 1 2 NEXT. Thread Tools. Display Modes. # 1. 10-09-2007, 05:12 PM. Oatman. Join Date: Oct 2007. Location: Philadelphia/NYC areas. Posts: 37 - iTrader: 0. Genetic engineering possibilities with Genus Radius/JS. Or help me understand the frankenstein possibilities of the radius/JS family of guitars. I have some part compatibility and general hardware confusion questions for various forms of the Radius/JS. I did do a lot of reading before posting, so I’m not totally inconsiderate . 1 Neck swappage. Other than the ’93 – ish AANJ-Wizardized Radii; do all fo...
http://jemsite.com/forums/f17/genetic-engineering-possibilities-with-genus-radius-js-68830.html
*  .. Industrial Application of Microbes .. Genetic Engineering of Microbes .. Food and Agriculture &
Industrial Application of Microbes. Microbes have been used to produce products for thousands of years. Even in ancient times, vinegar was made by filtering alcohol through wood shavings, allowing microbes growing on the surfaces of the wood pieces to convert alcohol to vinegar. Likewise, the production of wine and beer uses another microbe — yeast — to convert sugars to alcohol. Even though people did not know for a long time that microbes were behind these transformations, it did not stop them from making and selling these products. Both of these are early examples of biotechnology — the use of microbes for economic or industrial purposes. This field advanced considerably with the many developments in microbiology, such as the invention of microscope. Once scientists learned about the genetics of microbes, and how their cells produce proteins, microbes could also be altered to function in many new, and useful, ways. This sparked the application of biotechnology to many industries, such as agriculture, energ...
http://microbes.org/microbes-importance/industrial-application-of-microbes
*  A Sharper Tool for Genome Engineering | HMS
A Sharper Tool for Genome Engineering. HMS. HMS. Introduction to Clinical Research Training Medical Education. Dean for Medical Education Admissions Financial Aid Registrar MD Programs Curriculum Services Program Evaluation and Student Assessment. United Kingdom Clinical Scholars Research Training Vanderbilt Hall Admissions Financial Aid Office of the Registrar Campus Planning and Facilities Ombuds Office Committee on Microbiological Safety Human Resources HMS Foundation Funds Office for Academic and Clinical Affairs Joint Committee on the Status of Women Finance The Academy Global Health Research Core @HMS Global Clinical Scholars Research Training Program HMA Standing Committee on Animals Office of Research Compliance Global Community Health Harvard Medical School Event Calendar 2012 Biography Contact @HMS Office of Diversity RIA Program Research Talks@12 The Dean s Perspective Videos Microfluidics Department of Pathology 2011 Harvard Mahoney Neuroscience Institute Lync OHRA Home Office of Research Subject ...
http://hms.harvard.edu/news/genetics/sharper-tool-genome-engineering-1-11-13
*  .. FAQs .. Stay Up to Date! .. GE Apples & Potatoes - Tell Stores You Won't Buy Them! .. Recent Pos
FAQs. What’s a GMO. A GMO genetically modified organism is the result of a laboratory process of taking genes from one species and inserting them into another in an attempt to obtain a desired trait or characteristic, hence they are also known as transgenic organisms. This process may be called either Genetic Engineering GE or Genetic Modification GM ; they are one and the same. But haven’t growers been grafting trees, breeding animals, and hybridizing seeds for years. Genetic engineering is completely different from traditional breeding and carries unique risks. In traditional breeding it is possible to mate a pig with another pig to get a new variety, but is not possible to mate a pig with a potato or a mouse. Even when species that may seem to be closely related do succeed in breeding, the offspring are usually infertile. A horse, for example, can mate with a donkey, but the offspring a mule is sterile. With genetic engineering, scientists can breach species barriers set up by nature. For example, they ha...
http://responsibletechnology.org/gmo-education/faqs/
*  .. Tag Archives: transgenic .. Wonderful Things: transgenic mice
Tag Archives: transgenic. Wonderful Things: transgenic mice. Leave a reply. Down at the far end of Making the Modern World sit two still white mice. Don’t panic. These mice aren’t vermin; they are in fact two freeze dried transgenic mice. Two freeze dried genetically engineered mice, 1988. Image SSPL. The pair are direct descendants of the first transgenic mammals to be granted a US patent; among the first to be produced at Harvard Medical School in 1988. Their relatives had their genome altered through genetic engineering: by inserting an extra piece of DNA taken from a virus the mice are more prone to developing cancers. This particular strain of mouse, known as ‘ Oncomouse ’ is used in biomedical research for the development and discovery of treatment and cures for the disease. Nowadays, genetic engineering in mammals is becoming more vital in the development of immunisation in livestock. Does this type of genetic engineering and testing sit happily with everyone. It appears not. Some see it as med...
http://blog.sciencemuseum.org.uk/talkscience/tag/transgenic/
*  Biotech: Genetic Engineering - AP Biology Video by Brightstorm
3,630 views. Restriction enzymes are special proteins found in bacteria that are used by the bacteria to chop up viral DNA before the virus has a chance it kill the bacteria. Or they could also do it to any other sequence of DNA, that’s been cut with the exact same restriction enzyme, because they leave identical overlapping ends. Well the thing is, if you can this vector DNA, the DNA you can use to get it into this cell that you’re trying to genetically engineer. If you cut your vector DNA with the exact same enzyme as you used to cut the donor DNA; the DNA that you want to take a new gene out of, then you can mix them together. Well, after you’ve put together your donor DNA, and your vector DNA, takes you some heat and denature the restriction enzymes. And so what will happen is, if you can get a plasmid with your recombinant DNA into the bacteria, then it will follow the interactions you just gave it. So now that we’ve got a recombinant DNA now the challenge is getting it into the cell. If you'd used a...
http://brightstorm.com/test-prep/ap-biology/ap-biology-videos/biotech-genetic-engineering/
*  What Goes On in the Cytoplasm - Introduction to Genetic Engineering
... Home. Introduction. Nucleic Acids. Eukaryotic Cell Layout. Chemical Reactions Enzymes Cytoplasm. Enzyme Proteins. DNA Replication. Chromosome. Protein Synthesis. Cloning. DNA. Stem Cells. Contact Us. Help. Glossary. Home. Introduction. Chemical Reactions Enzymes What Goes On in the Cytoplasm. What Goes On in the Cytoplasm Thousands and thousands of different chemical reactions take place in the cytoplasm. Here's an example of a very generic chemical reaction:. In the above reaction, molecules X and Y are the reactants and molecule Z is the product. However, the reaction won't happen unless X and Y get together. X and Y need a mutual "friend" that will help them get together in the same place at the same time so they can react and form Z. The mutual friend is an enzyme. Here's a picture of an enzyme that would work nicely to get X and Y together. We'll call the enzyme molecule E. If E is around, the reaction between X and Y occurs much more quickly than if E is not around. We call E a catalyst. Catalysts ...
http://bootstrike.com/Genetics/Intro/cytoplasm.php
*  jcdutton/libbeauty · GitHub
... Skip to content. Sign up Sign in. This repository. Explore. Features. Enterprise. Pricing. Watch. jcdutton. / libbeauty. Code Issues. Pulse Graphs HTTPS clone URL. Subversion checkout URL. You can clone with. Subversion. Decompiler and Reverse Engineering tool. 1,073 commits. Objective-C 19.8%. HTML 4.1%. PHP 2.3%. C Objective-C C++ HTML PHP Shell Other Branch: master. Switch branches/tags. Branches. Tags. master. libbeauty. / Add FileCheck binary, saves users from building LLVM from source. … Make the makefile build the libs first, before the test files. latest commit 19d938a11a. jcdutton authored Aug 29, 2015. Failed to load latest commit information. dis Initial import of test code. libbeauty Add FileCheck binary, saves users from building LLVM from source. Aug 29, 2015. www/ htdocs Update status, using GIT and not SVN. Mar 27, 2012. README.md Fix typo. Mar 12, 2014. README.md libbeauty Decompiler and Reverse Engineering tool The current aim has been changed to the following: 1 Take a x86 64 binary .o...
https://github.com/jcdutton/libbeauty
*  Metagenics
... the word metagenics uses the prefix meta and the suffix gen literally it means the creation of something which creates in the context of biotechnology metagenics is the practice of engineering organisms to create a specific enzyme protein or other biochemicals from simpler starting materials the genetic engineering of e coli with the specific task of producing human insulin from starting amino acids is an example category biotechnology category genetic engineering...
https://en.wikipedia.org/wiki/Metagenics
*  Gene editing
... may refer to genome editing genetic engineering of any organism by genome editing gene therapy the therapeutic delivery of nucleic acid polymers into a patient s cells as a drug to treat disease category genetic engineering...
https://en.wikipedia.org/wiki/Gene_editing
*  Protein engineering
... There are two general strategies for protein engineering, 'rational' protein design and directed evolution. Eventually, even unnatural amino acids may be incorporated, thanks to a new method that allows the inclusion of novel amino acids in the genetic code. Approaches Rational design. Directed evolution. Examples of engineered proteins Enzyme engineering. See also References External links. Rational design. Protein design. In rational protein design, the scientist uses detailed knowledge of the structure and function of the protein to make desired changes. Computational protein design algorithms seek to identify novel amino acid sequences that are low in energy when folded to the pre-specified target structure. Directed evolution. Directed evolution. This method mimics natural evolution and, in general, produces superior results to rational design. 2 The advantage of directed evolution is that it requires no prior structural knowledge of a protein, nor is it necessary to be able to predict what effect a...
https://en.wikipedia.org/wiki/Protein_engineering
*  Engineering studies
... 'Engineering studies' is an interdisciplinary branch of social sciences and humanities devoted to the study of engineers and their activities. Studying engineers refers among other to the history and the sociology of their profession, its institutionalization and organization, the social composition and structure of the population of engineers, their training, their trajectory, etc. Studying engineering refers to the study of their activities and practices, their knowledge and ontologies, their role into the society, their engagement. Engineering studies investigate how social, political, economical, cultural and historical dynamics affect technological research, design, engineering and innovation, and how these, in turn, affect society, economics, politics and culture. Sometimes Engineering studies refers to Engineering education. Subfields and related fields Concepts Journals Associations References External links. History of engineering Sociology of engineers Women in engineering Engineering ethnograp...
https://en.wikipedia.org/wiki/Engineering_studies
*  User:Mitali Kini - OpenWetWare
Specific Idea: Combining the biophysical study of cellular lipid membrane properties and their influences on protein aggregation and misfolding, with the protein engineering study of GFP or luciferase-based reporters in detecting protein aggregation, we propose the design and creation of a chimeric fluorescent protein reporter that can bind to cellular lipid bilayers and detect aggregate formation in different tissues. Specific Idea: Combining the biophysical study of cellular lipid membrane properties and their influences on protein aggregation and misfolding, with the protein engineering study of GFP or luciferase-based reporters in detecting protein aggregation, we propose the design and creation of a chimeric fluorescent protein reporter that can bind to cellular lipid bilayers and detect aggregate formation in different tissues. Furthermore, it has been found that amyloid proteins form aggregates upon interaction with surfaces and lipid bilayers, and in some cases can cause cell death through permeabilit...
http://openwetware.org/index.php?title=User:Mitali_Kini&diff=696661&oldid=696660
*  Highest Voted 'protein-engineering' Questions - Biology Stack Exchange
Highest Voted 'protein-engineering' Questions - Biology Stack Exchange. chat blog. Biology. Biology Meta. more stack exchange communities. Stack Exchange. Help Center Detailed answers to any questions you might have. Biology Questions. Users. Unanswered. Tagged Questions info newest frequent votes active unanswered. The protein-engineering tag has no usage guidance. 405 views. Phagemid display If I'm using a bacteriophage for phage display and I'm trying to avoid avidity effects by using a helper phage what would be the best way to maintain a large library size while keeping everything ... protein-binding protein-engineering protein-evolution asked Apr 11 '12 at 9:01. 0 answers. 549 views. proteins structural-biology protein-binding protein-engineering structure-prediction community wiki. 196 views. molecular-biology protein-engineering asked Apr 11 '12 at 8:53. 3 answers. 230 views. Proteins folding Some of us are involved in the folding@home project, spending time, money and resources. proteins prot...
http://biology.stackexchange.com/questions/tagged/protein-engineering?sort=votes&pagesize=15
*  Protein Engineering Market Worth $168 Billion by 2017 | Mar 20, 2014 - SBWire
Protein Engineering Market Worth $168 Billion by 2017. Mar 20, 2014 - SBWire. SBWire Sign Up. Login. Our Service. Plans & Pricing. Newsroom. Help. About. MarketsandMarkets Email Alerts. RSS. Protein Engineering Market Worth $168 Billion by 2017 The global market was estimated at $100.1 billion in 2012, growing at a CAGR of 10.94% from 2012 to 2017. Dallas, TX -- SBWIRE -- 03/20/2014 -- The report "Protein Engineering Market - Global Forecast to 2017", analyses the global protein engineering market by products, technology, applications, and geography with five-year revenue forecasts. It also identifies the factors driving and restraining the global protein engineering market with analysis of trends, opportunities, and threats. Browse 11 market data tables with 44 figures spread through 148 Slides and in-depth TOC on "Protein Engineering Market". Early buyers will receive 10% customization on this report. Do Inquiry Before Buying@ http://www.marketsandmarkets.com/Enquiry Before Buying.asp?id=898. The global mar...
http://sbwire.com/press-releases/protein-engineering-market-worth-168-billion-by-2017-478760.htm
*  SCOPE (protein engineering)
SCOPE protein engineering. SCOPE protein engineering. 'Structure-Based Combinatorial Protein Engineering SCOPE ' is a synthetic biology technique for creating gene libraries lineages of defined composition designed from structural and probabilistic constraints of the encoded proteins. The development of this technique was driven by fundamental questions about protein structure, function, and evolution, although the technique is generally applicable for the creation of engineered proteins with commercially desirable properties. Combinatorial Travel Through Sequence Space-Time is the goal of SCOPE. At its inception, SCOPE was developed as a homology -independent recombination technique to enable the creation of multiple crossover libraries from distantly related genes. In this application, an “exon plate tectonics ” design strategy was devised to assemble “equivalent” elements of structure continental plates with variability in the junctions linking them fault lines to explore global protein space. To create ...
https://en.wikipedia.org/wiki/SCOPE_(protein_engineering)
*  RIT - NTID - Engineering Studies
... Search RIT. Search. Search NTID website Search all RIT websites. National Technical Institute for the Deaf. Success Stories. Center on Access Technology CAT. Center for Education Research Partnerships CERP. Research Center for Teaching and Learning RCfTL. Deaf Studies Laboratory DSL. RIT/NTID in the News. RIT/NTID News Video. RIT University News. Resources for Faculty and Staff. Updates from the NTID President s Office RIT login required. Sign Language and Deafness Educational Materials. Financial Aid Scholarships. RIT Office of Financial Aid Scholarships. Associate+Bachelor s Degree Programs. Bachelor s Degree Programs. Program Options Associate+Bachelor s Degree Program in Applied Mechanical Technology Associate+Bachelor s Degree Program in Civil Technology Computer Aided Drafting Technology Computer Integrated Machining Technology. About the Department Faculty Staff Student Profiles Department News Contact Chairperson Mission Statement CAST and COE Support Services. RIT User Login Current students, fa...
http://ntid.rit.edu/engineering
*  NIDA NOTES - Genetic Engineering Studies May Lead to Development Of More Effective Pain Relievers
... Genetic Engineering Studies May Lead to Development Of More Effective Pain Relievers. Morphine and related compounds, called opiates, are among the most effective pain-relieving medications currently available. Differences in Degree Although all opiates cause physiological tolerance with prolonged administration, the degree of tolerance produced can vary considerably from drug to drug, even under similar conditions. Understanding how opiates differ in their effects on these receptors may help explain the biological underpinnings of opiate tolerance and may be useful in developing improved opiate analgesics, Dr. Morphine and many other opiates produce analgesia by activating a type of opioid receptor called the mu opioid receptor. von Zastrow and his colleagues believe that differences in this process of endocytosis may be a determining factor in whether or not a drug will produce tolerance. Understanding how opiates differ in their effects on these receptors may help explain the biological underpinnings ...
http://archives.drugabuse.gov/NIDA_Notes/NNVol15N3/Genetic.html
*  Lwarcel Celulose Hires Pöyry for Engineering Study on Pulp Mill Expansion
... home subscription services editorial calendar media guide events calendar industry links about us contact lwarcel celulose hires pöyry for engineering study on pulp mill expansion lwarcel celulose plans to increase the production capacity of its pulp mill in são paulo brazil from tpy to tpy june pöyry said that it has been awarded a contract by lwarcel celulose for basic engineering and logistics studies for the expansion of its pulp mill at lençóis paulista são paulo brazil the value of the deal was not disclosed lwarcel had earlier engaged pöyry s services in the conceptual and pre feasibility analysis for the project as part of the expansion lwarcel intends to build a new production line at the same location of the current mill the line will bring an additional production capacity of up to tons a year currently the annual production is tons of short fibre pulp from eucalyptus in addition to the new production line the project also plans for an increase of the company s planting area going from acres t...
http://paperage.com/2013news/06_20_2013poyry_lwarcel_celulose.html
*  FDLI, PEN co-sponsor major conference on nano... ( Nanotechnology was incorporated into...)
"Advances in monoclonal antibody therapeutics " ... "Global Protein Therapeutics Market Outlook 2020" ... Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics...
http://bio-medicine.org/biology-news-1/FDLI--PEN-co-sponsor-major-conference-on-nanotechnology-1536-1/
*  Genome engineering
... Zinc finger nuclease-based Engineering. Early approaches to genome engineering involved modifying genetic sequences using only homologous recombination. Evans, they developed a process for the modification of the mouse genome by modifying the DNA of mouse embryonic stem cells in culture and injecting these modified stem cells into mouse embryos. 1 Methods in genome engineering:. MAGE experiments can be divided into three classes, characterized by varying degrees of scale and complexity: i many target sites, single genetic mutations; ii single target site, many genetic mutations; and iii many target sites, many genetic mutations. With recognition sites of over 12 base pairs, meganucleases and zinc finger nucleases offer this degree of precision. By acting on these recognition sites, they have been able to generate variants that interact with different DNA sequences from those of the initial meganucleases, while retaining their ability to cut the DNA and their high degree of specificity. Zinc finger nuclea...
https://en.wikipedia.org/wiki/Genome_engineering
*  ProteinGPS & Enzyme Engineering Technology - DNA2.0
ProteinGPS Enzyme Engineering Technology - DNA2.0. ProteinGPS Engineering. Projects. Literature database Search. ProteinGPS Engineering. ProteinGPS Engineering Technology Quickly and efficiently design proteins with improved characteristics to find the protein activity you need. Advantages DNA2.0 combines state-of-the-art gene synthesis with cutting edge machine learning and ‘big data’ to explore and exploit sequence-function relationships, identifying protein variants with significantly improved characteristics; typically assaying 96-400 variants over 3-5 rounds. The ProteinGPS gene variants Infologs enable efficient DoE based sampling of the entire sequence-function space. Depending on functional activity outcome from the homologs, it may be relevant to further drill down into one or more of the richer phylogenetic branches for synthesis and testing of additional related homologs. The ProteinGPS process may use one, two, or more starting points for the subsequent ProteinGPS engineering depending on the outc...
https://dna20.com/services/proteingps
*  Medical Xpress - protein engineering
... Home protein engineering. News tagged with protein engineering. 1 week. 1 month. 1 week. 1 month. 1 week. Medical research. Tissues stiffen with age, poor diet, disease and for natural reasons, and when they do, a new study shows, proteins produced by such cells can be altered, which in turn affects downstream processes. Through a combination of natural immune selection and targeted protein engineering, A*STAR researchers have generated an antibody that efficiently blocks a disease-related inflammatory pathway in both human cells and mouse ... Alzheimer's disease & dementia. Compound reverses symptoms of Alzheimer's disease in mice, research shows. HIV & AIDS. Experimental HIV vaccine targets virus envelope protein. Now, a new type of vaccine developed within the EU-funded project EuroNeut-41, targets an HIV envelope protein called the gp41. Parkinson's & Movement disorders. Research yields first detailed view of morphing Parkinson's protein. Medical Xpress —Researchers have taken detailed images and mea...
http://medicalxpress.com/tags/protein engineering/
*  User:NYOUSHA Yousefi/Notebook/Protein Engineering/2013/01/22 - OpenWetWare
... User:NYOUSHA Yousefi/Notebook/Protein Engineering/2013/01/22 From OpenWetWare User:NYOUSHA Yousefi. Notebook. Protein Engineering. 2013. 01 Revision as of 09:27, 29 January 2013 by NYOUSHA Yousefi Talk. contribs diff ←Older revision. Current revision diff. Newer revision→ diff. Jump to: navigation, search. Project name. Main project page Previous entry Next entry. Entry title. Culturing antibiotic resistant bacteria producing myoglobin and hemoglobin. Objective 1. Ampicillin and Kenamycin were the antibiotics used for culturing. Procedure 1. 5ml of LB medium was added to two set of sterile tubes by 10 ml pipets 5ul of Ampicillin was added to one tube and Kenamycin was added to the other tube The frozen cells in glycerol were taken out of the -80 degree C fridge Bacteria expressing Myoglobin were added to the media tube containing Ampicillin because it has Ampicillin resistance PQE-80 bacteria were added to media tube containing Kenamycin becasue it has Kenamycin resistance The tubes were places in the in...
http://openwetware.org/index.php?title=User:NYOUSHA_Yousefi/Notebook/Protein_Engineering/2013/01/22&curid=129647&oldid=671362
*  Novel antitoxin strategy developed using 'tagged bindi... (a 2002 breakthrough at the University of.
"Advances in monoclonal antibody therapeutics " ... Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 6 Global Animal Biotechnology Report 2015-2024 - Appl...
http://bio-medicine.org/biology-news-1/Novel-antitoxin-strategy-developed-using-tagged-binding-agents-12038-2/
*  SNM applauds NAS study showing need to restore federal nuclear medicine resear... (pecialty that use
"Global Protein Therapeutics Market Outlook 2020" ... Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 6 Global Animal Biotechnology Report 2015-2024 - Ap...
http://bio-medicine.org/biology-news-1/SNM-applauds-NAS-study-showing-need-to-restore-federal-nuclear-medicine-research-funding-476-3/
*  Rabbit Anti-Human Macrophage-stimulating protein receptor Polyclonal Antibody, Unconjugated from Gen
Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 6 Global Animal Biotechnology Report 2015-2024 - Applications in Veterinary Medicine and Pharmaceuticals ...
http://bio-medicine.org/biology-products/Rabbit-Anti-Human-Macrophage-stimulating-protein-receptor-Polyclonal-Antibody--Unconjugated-from-GenWay-Biotech--Inc--5551-1/
*  Virus attacks childhood cancers ( Researchers from Yale University are...)
Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 6 Global Animal Biotechnology Report 2015-2024 - Applications in Veterinary Medicine and Pharmaceuticals ...
http://bio-medicine.org/biology-news-1/Virus-attacks-childhood-cancers-21014-1/
*  Increased Light Leads to Early Detection: Caliper Life Sciences Introduces Bioware(R) Ultra Cancer .
Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 6 Global Animal Biotechnology Report 2015-2024 - Applications in Veterinary Medicine and Pharmaceuticals ...
http://bio-medicine.org/biology-technology-1/Increased-Light-Leads-to-Early-Detection-3A-Caliper-Life-Sciences-Introduces-Bioware-28R-29-Ultra-Cancer-Cell-Lines-4614-1/
*  Stress hormones may play new role in speeding up cancer growth ( New research here suggests that hor
Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 6 Global Animal Biotechnology Report 2015-2024 - Applications in Veterinary Medicine and Pharmaceuticals ...
http://bio-medicine.org/biology-news/Stress-hormones-may-play-new-role-in-speeding-up-cancer-growth-4434-1/
*  Top cancer specialists receive E... (systematic approach to all details in st...)
Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 6 Global Animal Biotechnology Report 2015-2024 - Applications in Veterinary Medicine and Pharmaceuticals ...
http://bio-medicine.org/biology-news-1/Top-cancer-specialists-receive-ESMO-awards-15392-3/
*  World class to second class? Confronting the risks to US science and ... ( A Research!America Disc
Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 6 Global Animal Biotechnology Report 2015-2024 - Applications in Veterinary Medicine and Pharmaceuticals ...
http://bio-medicine.org/biology-news-1/World-class-to-second-class-3F--Confronting-the-risks-to-US-science-and-innovation-23612-1/
*  New generation of micro sensors for monitoring ocean aci... (p The microfluidic chip within the sens
Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 6 Global Animal Biotechnology Report 2015-2024 - Applications in Veterinary Medicine and Pharmaceuticals ...
http://bio-medicine.org/biology-news-1/New-generation-of-micro-sensors-for-monitoring-ocean-acidification-32470-2/
*  Wisconsin Should Create, like Renewables, an Energy Efficient Portfolio ( A Golden Age of Energy Ef
Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 6 Global Animal Biotechnology Report 2015-2024 - Applications in Veterinary Medicine and Pharmaceuticals ...
http://bio-medicine.org/biology-technology/Wisconsin-Should-Create--like-Renewables--an-Energy-Efficient-Portfolio-4852-1/
*  American Chemical Society's Weekly PressPac -- Nov... (lements: An ACS Science News Podcast ....)
Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 6 Global Animal Biotechnology Report 2015-2024 - Applications in Veterinary Medicine and Pharmaceuticals ...
http://bio-medicine.org/biology-news-1/American-Chemical-Societys-Weekly-PressPac----Nov--14--2007-1260-9/
*  3D X-ray film: Rapid movements in... (omena occur which highlight the inner an...)
Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 6 Global Animal Biotechnology Report 2015-2024 - Applications in Veterinary Medicine and Pharmaceuticals ...
http://bio-medicine.org/biology-news-1/3D-X-ray-film-3A-Rapid-movements-in-real-time-34565-2/
*  medicine-news-1/nursing-home-flu-shots-fall-short--especially-for-blacks-85710-1/
Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 6 Global Animal Biotechnology Report 2015-2024 - Applications in Veterinary Medicine and Pharmaceuticals ...
http://bio-medicine.org/medicine-news-1/Nursing-home-flu-shots-fall-short--especially-for-blacks-85710-1/
*  Regulation of TATA-less promoters ( In their upcoming G&D paper Dr. Robe...)
Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 6 Global Animal Biotechnology Report 2015-2024 - Applications in Veterinary Medicine and Pharmaceuticals ...
http://bio-medicine.org/biology-news-1/Regulation-of-TATA-less-promoters-1077-1/
*  Researchers discover workings of brain's 'G... (off as the mouse moved away from that po...)
Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 6 Global Animal Biotechnology Report 2015-2024 - Applications in Veterinary Medicine and Pharmaceuticals ...
http://bio-medicine.org/biology-news-1/Researchers-discover-workings-of-brains-GPS-system-29294-2/
*  Ceelox Provides Biometric Identity Access to Cloud Ap... (esults could differ from those projected..
Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 6 Global Animal Biotechnology Report 2015-2024 - Applications in Veterinary Medicine and Pharmaceuticals ...
http://bio-medicine.org/biology-news-1/Ceelox-Provides-Biometric-Identity-Access-to-Cloud-Applications-18811-3/
*  The 'appetite-suppressing' effect of proteins... (of the intestine. These receptors are in...)
Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 6 Global Animal Biotechnology Report 2015-2024 - Applications in Veterinary Medicine and Pharmaceuticals ...
http://bio-medicine.org/biology-news-1/The-appetite-suppressing-effect-of-proteins-explained-25720-2/
*  Physicists measure current-induced torque in nonvolatile magnetic memor... ( ITHACA N.Y. - Tomorrow
Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 6 Global Animal Biotechnology Report 2015-2024 - Applications in Veterinary Medicine and Pharmaceuticals ...
http://bio-medicine.org/biology-technology-1/Physicists-measure-current-induced-torque-in-nonvolatile-magnetic-memory-devices--18814-1/
*  biology-news-1/can-peer-mentors-help-teens-lose-weight-3f-new-strategies-for-combatting-teen-obesity
Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 6 Global Animal Biotechnology Report 2015-2024 - Applications in Veterinary Medicine and Pharmaceuticals ...
http://bio-medicine.org/biology-news-1/Can-peer-mentors-help-teens-lose-weight-3F-new-strategies-for-combatting-teen-obesity-21680-2/
*  Landfill nation: What makes consumers less likely t... (sychological processes influencing recyc...)
Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 6 Global Animal Biotechnology Report 2015-2024 - Applications in Veterinary Medicine and Pharmaceuticals ...
http://bio-medicine.org/biology-news-1/Landfill-nation-3A-What-makes-consumers-less-likely-to-recycle-3F-31414-2/
*  BioWorks 3.3 from Thermo Scientific
Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 6 Global Animal Biotechnology Report 2015-2024 - Applications in Veterinary Medicine and Pharmaceuticals ...
http://bio-medicine.org/biology-products/BioWorks-3-3-from-Thermo-Scientific-2258-1/
*  Methods in Protein Design | 978-0-12-394292-0 | Elsevier
Methods in Protein Design. Elsevier. Methods in Protein Design This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. This volume covers methods in protein design and it has chapters on such topics as protein switch engineering by domain insertion, evolution based design of proteins, and computationally designed proteins. View full description. Table of Contents Computational Design of Novel Protein Binders and Experimental Affinity Maturation. Timothy A Whitehead, David Baker, and Sarel J Fleishman Mining Tertiary Structural Motifs for Assessment of Designability Jian Zhang, Gevorg Grigoryan Computational Methods for Controlling Binding Specificity Oz Sharabi, Ariel Erijman, and Julia M. Shifman Methods in Enzymology: "Flexible Backbone Sampling Methods to Model and Design Protein Alternative Conformations" Noah Ollikainen, Colin A. Richardson, Jane S. Gray, Tanja Kortemme, Jane S. Richardson, James J. Havranek, Ja...
http://elsevier.com/books/methods-in-protein-design/unknown/978-0-12-394292-0
*  Pages that link to "BE.109" - OpenWetWare
Pages that link to BE.109 - OpenWetWare. Pages that link to BE.109 From OpenWetWare List of links Jump to: navigation, search BE.109. Namespace: all Main Talk User User talk OpenWetWare OpenWetWare talk Image Image talk MediaWiki MediaWiki talk Template Template talk Help Help talk Category Category talk List List talk Notebook Notebook talk Widget Widget talk. Filters Hide transclusions. Hide links. Hide redirects The following pages link to BE.109 :. View previous 50 next 50 20. User:Reshma P. Main Page v2. OpenWetWare:News. ICampus Application for OWW. BE.109:General lab policy. Template:BE.109. BE.109:Guidelines for maintaining your lab notebook. BE.109:Guidelines for oral presentations. BE.109:Guidelines for writing a lab report. BE.109:Guidelines for working in the tissue culture facility. BE.109:Lab. BE.109:Bio-material engineering. BE.109:Bio-material engineering/Optimizing panning. BE.109:Bio-material engineering/Screening library and optimizing panning. ICampus Application for OWW/Official wiki vers...
http://openwetware.org/index.php?title=Special:WhatLinksHere&target=BE.109
*  Recent Articles | Protein Engineering, Evolution And Immunology | The Scientist Magazine®
Recent Articles. Protein Engineering, Evolution And Immunology. The Scientist Magazine. The Scientist Sign In or Register. Advertisement. The Scientist. tags: protein engineering x. evolution x. immunology x. The Scientist protein engineering, evolution and immunology. Most Recent Polar Dino Discovered By Bob Grant. September 28, 2015. Researchers working in Alaska, above the Arctic Circle, have unearthed the northernmost species of dinosaur ever found. 0 Comments. Tree of Life v1.0 By Jef Akst. September 22, 2015. Researchers map 2.3 million species in a single phylogeny. 0 Comments. Dengue’s Downfall. By Jef Akst. September 15, 2015. Researchers characterize a protein that could be key to the virus s virulence and to developing a vaccine against the mosquito-borne disease. 0 Comments. New Homo Species Found By Bobby Bascomb. September 10, 2015. Researchers describe H. naledi, an ancient human ancestor of unknown age that may have buried its dead. 8 Comments. Immune Cells Can Deliver Deadly Packages By Ama...
http://the-scientist.com/?articles.list/categoryNo/2625/category/The-Scientist/tagNo/58,8,12/tags/protein-engineering,evolution,immunology/
*  Innovalight Establishes New Record With Silicon Ink S... (tion technology and prototypes to the co..
Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 6 Global Animal Biotechnology Report 2015-2024 - Applications in Veterinary Medicine and Pharmaceuticals ...
http://bio-medicine.org/biology-news-1/Innovalight-Establishes-New-Record-With-Silicon-Ink-Solar-Cells-13038-3/
*  King of beasts losing ground in Uganda'... ( The crisis in lion conservation i...)
Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 6 Global Animal Biotechnology Report 2015-2024 - Applications in Veterinary Medicine and Pharmaceuticals ...
http://bio-medicine.org/biology-news-1/King-of-beasts-losing-ground-in-Ugandas-paradise-32064-3/
*  Feature package of Congo Basin forest photos, stories &a... ( Stretching across central Africa the.
Breaking Biology Technology: Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 2 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 3 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 4 Advances in Monoclonal Antibody Therapeutics - 2015 Market Report 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 2 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 3 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 4 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 5 Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics 6 Global Animal Biotechnology Report 2015-2024 - Applications in Veterinary Medicine and Pharmaceuticals ...
http://bio-medicine.org/biology-news-1/Feature-package-of-Congo-Basin-forest-photos--stories--26amp-3B-videos-27532-1/
*  Structure Based Drug Design (SBDD) Consulting, Services and Outsouring
Structure Based Drug Design SBDD Consulting, Services and Outsouring. BREWING YOUR SUCCESS BY ENRICHING PIPELINE WITH OUR EFFECTIVENESS Home. Services. Structure Based Rational Design. About Company. Sitemap. Welcome to Rebexsess Discovery Chemistry. Rebexsess Discovery Chemistry provides the world class contract research services in 3D protein structure based rational design and modeling. 3D Models of protein-ligand complexes are used to create both novel small molecules and proteins with new functions. Rebexsess has this unique capability of designing not only small molecular as drug candidates, but also engineered proteins as novel enzymes. This skill set has been proven to be powerful and effective in both drug discovery and protein/enzyme engineering. The multidisciplinary expertise of Rebexsess will cut the timeline in the discovery stage and be cost effective. Rebexsess research experiences can help to minimize the risks for clinical trial from early stage of drug discovery cycle, and to contribute to ...
http://rebexsess.com/
*  Antibody therapeutics
... redirect monoclonal antibody therapy...
https://en.wikipedia.org/wiki/Antibody_therapeutics
*  Category:Protein engineering
category protein engineering category protein engineering category proteins...
https://en.wikipedia.org/wiki/Category:Protein_engineering
*  Small-screw insertion system re-engineered to accommodate interchangeable nose assemblies - TheFabri
... cator.com. Aluminum Welding. Assembly and Joining. Laser Cutting. Laser Welding. Metals/Materials. Tube and Pipe Fabrication. Tube and Pipe Production. Industry Directory. Publications. Subscriptions. Small-screw insertion system re-engineered to accommodate interchangeable... Small-screw insertion system re-engineered to accommodate interchangeable nose assemblies October 11, 2010. PennEngineering 's PEM StickScrew system for small-screw insertion has been re-engineered with a new StickShooter driver, offering the capability to accommodate interchangeable nose assemblies and allow for quick tooling changeover. The self-contained system combines the air-powered driver with sticks of serially connected hex-head screws, enabling automatic screw installation without handling loose screws or driving them manually. The standard product line includes thread-cutting screws from #2-56 to #6-32 and M3 in 400 series stainless steel. Other available types and sizes include machine screws and thread-forming screws in...
http://thefabricator.com/product/assembly/small-screw-insertion-system-re-engineered-to-accommodate-interchangeable-nose-assemblies
*  Zymeworks Inc. — Technology Overview
... About. Overview. News. Management Team. Board of Directors. Advisors. Investors. Fact Sheet PDF. Pipeline. Platform. Azymetric Scaffold. AlbuCORE Scaffold. EFECT Platform. Technology. Overview. ZymeCAD Platform. Protein Engineering. Partnering. Corporate. Academic. Government. Careers. Career Opportunities. Corporate Culture. Benefits. Contact. Contact. Maps Parking. Technology Overview. Zymeworks has developed a leading-edge molecular simulation platform ZymeCAD™ for protein modeling and structure-guided optimization with the unparalleled ability to relate the function and biophysical characteristics of a protein to its structure. The proprietary insight generated by the ZymeCAD™ platform enables Zymeworks to engineer knowledge based structural modifications that result in new or improved protein based drugs. The Zymeworks protein engineering process relies on a two-expert approach, where proprietary biophysical insight generated by the ZymeCAD™ platform is used by in-house protein engineers to make kno...
http://zymeworks.com/technology/index.html
*  De novo computational design of retro-aldol enzymes | The Baker Laboratory
De novo computational design of retro-aldol enzymes. The Baker Laboratory. Skip to Main Content Area. news research Members Past Members publications employment contact info Links. De novo computational design of retro-aldol enzymes. Title. De novo computational design of retro-aldol enzymes. Publication Type. Journal Article. Year of Publication. 2008. Authors. Jiang, L. , Althoff E. A , Clemente F. R , Doyle L. , Röthlisberger D. , Zanghellini A. , Gallaher J. L , Betker J. L , Tanaka F. , Barbas C. F , Hilvert D. , Houk K. N , Stoddard B. L , & Baker D. Journal. Science. Volume. 319. Issue. 5868. Pagination. 1387-91. Date Published. 2008 Mar 7. ISSN. 1095-9203. Keywords. Aldehyde-Lyases , Algorithms , Binding Sites , Catalysis , Catalytic Domain , Computer Simulation , Crystallography, X-Ray , Hydrogen Bonding , Hydrophobicity , Kinetics , Models, Molecular , Primary Publication , Protein Conformation , Protein Engineering. The creation of enzymes capable of catalyzing any desired chemical reaction is a gr...
http://bakerlab.org/node/151/
*  Zymeworks Inc. — ZymeCAD™ Platform
ZymeCAD™ consists of a suite of proprietary algorithms that are used to: Develop high quality models of the protein therapeutics’ structure and its complexes with targets or other proteins Optimize conformations and sample the diversity Provide critical insight into the intrinsic dynamic nature of the protein therapeutic. Structural characteristics of the protein therapeutic and targets are studied in the context of energy scoring functions calibrated against empirically observed thermodynamic properties of the system. Molecular Models High quality structural models of protein systems are a critical component in Zymeworks Protein Engineering Approach. Zymeworks Platform includes a number of proprietary tools used to build and refine the quality of models, incorporating structural data from multiple sources including homology and sequence data from related proteins, experimental binding information and mutational analysis such as alanine scanning. Conformational Dynamics Zymeworks Platform incorporates a numbe...
http://zymeworks.com/technology/zymecad.html
*  MorphoSys and Heptares Sign Alliance to Develop Antibody Therapeutics Targeting GPCRs | SYS-CON IND
MorphoSys and Heptares Sign Alliance to Develop Antibody Therapeutics Targeting GPCRs. SYS-CON INDIA. Jump to a SYS-CON Magazine .NET Developer's Journal Apache.SYS-CON.com AjaxWorld Magazine - AWM CMS.SYS-CON.com ColdFusion Developer's Journal CRM.SYS-CON.com Eclipse Developer's Journal Enterprise Open Source Magazine Flex Developer's Journal - Flex HP.SYS-CON.com Internet Video - iTV iPhone Developer's Journal - iPHONE IT Solutions Guide Java Developer's Journal Linux.SYS-CON.com Open Web Developer's Journal Oracle.SYS-CON.com Perl.SYS-CON.com PHP.SYS-CON.com PowerBuilder Developer's Journal Python.SYS-CON.com RedHat.SYS-CON.com Ruby.SYS-CON.com SEO/SEM Search Journal Silverlight Developer's Journal SaaS.SYS-CON.com SAP.SYS-CON.com SOAWorld Magazine - SWM Symbian Developer's Journal Virtualization.SYS-CON.com Web 2.0 Journal WebLogic Journal WebSphere Journal Wireless Business & Technology XML Journal. The World s Leading Resource on SOA / Web Services. Register. Log in. .NET. AJAX. ECLIPSE. FLEX. OPEN WEB....
http://in.sys-con.com/node/2537468
*  Rop protein
... also known as repressor of primer is a small protein responsible for keeping the copy number of cole and related bacterial plasmids low in e coli structurally rop is a homodimeric four helix bundle protein formed by the antiparallel interaction of two helix turn helix monomers the rop protein s structure has been solved to high resolution due to its small size and known structure rop has been used in protein design work to rearrange its helical topology and reengineer its loop regions in general the four helix bundle has been extensively used in de novo protein design work as a simple model to understand the relationship between amino acid sequence and structure references category proteins...
https://en.wikipedia.org/wiki/Rop_protein
*  Zymeworks Inc. — HL‧Max™ Platform
... About. Overview. News. Management Team. Board of Directors. Advisors. Investors. Fact Sheet PDF. Programs. Overview. Pipeline. Azymetric Scaffold. AlbuCORE Scaffold. EFECT Platform. HL‧Max Platform. Technology. Overview. ZymeCAD Platform. Protein Engineering. Partnering. Corporate. Academic. Government. Careers. Career Opportunities. Corporate Culture. Benefits. About Vancouver. Contact. Contact. Maps Parking. HL‧Max™ Platform. Zymeworks is developing an optimized monoclonal antibody constant region platform centered on conferring improved serum half-life to IgG1 therapeutic antibodies. This early-stage program is focused on optimizing a pH-dependent rescue mechanism through the engineering of improved binding to the neonatal Fc receptor “FcRn” while maintaining efficient release in the serum. This platform will enable Zymeworks to design more efficacious antibody therapeutics, resulting in lower dosage requirements and improved localization to the disease target. Zymeworks Inc. Contact....
http://zymeworks.com/programs/hl-max.html
*  Functional nerve cells from skin cells | EurekAlert! Science News
Functional nerve cells from skin cells. EurekAlert. Science News. News. Breaking News. Medicine Health. Science Business News. EurekAlert!中文版. Breaking News. Science Business News. Medicine Health. EurekAlert. About EurekAlert. Help / FAQ. IMAGE: These are mature nerve cells generated from human cells using enhanced transcription factors. A new method of generating mature nerve cells from skin cells could greatly enhance understanding of neurodegenerative diseases, and could accelerate the development of new drugs and stem cell-based regenerative medicine. The nerve cells generated by this new method show the same functional characteristics as the mature cells found in the body, making them much better models for the study of age-related diseases such as Parkinson's and Alzheimer's, and for the testing of new drugs. Stem cells are our master cells, which can develop into almost any cell type within the body. However, by engineering proteins which cannot be modified by phosphate and adding them to human cells,...
http://eurekalert.org/pub_releases/2014-05/uoc-fnc052114.php
*  Announcement: the Lipase Engineering Database
http://bio.net/bionet/mm/bio-www/2000-February/000861.html
*  Computing toxic chemicals (thm against more than 300 chemicals for ...)
BioAmber Sarnia Producing High Quality Bio-Succinic Acid at Commercial Scale - Company Now Shipping Bio-Succinic Acid to Customers Advances in Monoclonal Antibody Therapeutics - 2015 Market Report Global Alzheimer Disease Report 2015-2024 - Latest New Drugs, Markets and Companies Analysis Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics....
http://bio-medicine.org/biology-news-1/Computing-toxic-chemicals-31064-2/
*  Stem cells in neurodegeneration: challenges and future neurotherapeutic... ( Researchers at the Uni
BioAmber Sarnia Producing High Quality Bio-Succinic Acid at Commercial Scale - Company Now Shipping Bio-Succinic Acid to Customers Advances in Monoclonal Antibody Therapeutics - 2015 Market Report Global Alzheimer Disease Report 2015-2024 - Latest New Drugs, Markets and Companies Analysis Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics....
http://bio-medicine.org/biology-news-1/Stem-cells-in-neurodegeneration-3A-challenges-and-future-neurotherapeutic-prospects-36264-1/
*  Researchers find drug that stops progression of Parkinson's disea... (nd a drug to turn on the DJ-1
BioAmber Sarnia Producing High Quality Bio-Succinic Acid at Commercial Scale - Company Now Shipping Bio-Succinic Acid to Customers Advances in Monoclonal Antibody Therapeutics - 2015 Market Report Global Alzheimer Disease Report 2015-2024 - Latest New Drugs, Markets and Companies Analysis Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics....
http://bio-medicine.org/biology-news-1/Researchers-find-drug-that-stops-progression-of-Parkinsons-disease-in-mice-18181-2/
*  Changing the conversation -- polymers disrupt bacterial com... ( Artificial materials based on simp
BioAmber Sarnia Producing High Quality Bio-Succinic Acid at Commercial Scale - Company Now Shipping Bio-Succinic Acid to Customers Advances in Monoclonal Antibody Therapeutics - 2015 Market Report Global Alzheimer Disease Report 2015-2024 - Latest New Drugs, Markets and Companies Analysis Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics....
http://bio-medicine.org/biology-news-1/Changing-the-conversation----polymers-disrupt-bacterial-communication-32413-1/
*  Midge-hunting scientists tackle spread of devastating blueto... (to understand how these outbreaks o
BioAmber Sarnia Producing High Quality Bio-Succinic Acid at Commercial Scale - Company Now Shipping Bio-Succinic Acid to Customers Advances in Monoclonal Antibody Therapeutics - 2015 Market Report Global Alzheimer Disease Report 2015-2024 - Latest New Drugs, Markets and Companies Analysis Global Protein Therapeutics Market Outlook 2020 - Players Investing Heavily in Multiple Sclerosis and Cancer Therapeutics....
http://bio-medicine.org/biology-news-1/Midge-hunting-scientists-tackle-spread-of-devastating-bluetongue-virus-4375-2/

Chromosome engineering: Chromosome engineering is "the controlled generation of chromosomal deletions, inversions, or translocations with defined endpoints." For: By combining chromosomal translocation, chromosomal inversion,and chromosomal deletion, chromosome engineering has been shown to identify the underlying genes that cause certain diseases in mice.Protein engineering: Protein engineering is the process of developing useful or valuable proteins. It is a young discipline, with much research taking place into the understanding of protein folding and recognition for protein design principles.Tissue Engineering and Regenerative Medicine International Society: Tissue Engineering and Regenerative Medicine International Society is an international learned society. Its goal is the worldwide advancement of both the science and technology of tissue engineering and regenerative medicine.Tank chassis: Tank container chassis, also referred to as tank chassis, drop frame chassis or tank trailers, are a form of intermodal transportation for portable bulk liquid containers or ISO tank containers. They are characteristically longer and have lower deck height ideal for transporting constantly shifting payloads.Biotechnology Industry Organization: The Biotechnology Industry Organization (BIO) is the largest trade organization to serve and represent the biotechnology industry in the United States and around the world.Anna Edney, "Biosciences Defy U.Plant perception (physiology): Plant perception is the ability of plants to sense and respond to the environment to adjust their morphology, physiology and phenotype accordingly. Other disciplines such as plant physiology, ecology and molecular biology are used to assess this ability.Institute of Biomaterials and Biomedical Engineering: The Institute of Biomaterials and Biomedical Engineering (IBBME) was founded in 1962 at the University of Toronto (U of T). IBBME is home to the common research and teaching interests of the faculties of Applied Science and Engineering, Dentistry, and Medicine at the U of T.American Mixed Breed Obedience Registry: The American Mixed Breed Obedience Registry (AMBOR) is a registry for mixed-breed dogs to enable them to compete in obedience and dog agility.Multiple cloning site: A multiple cloning site (MCS), also called a polylinker, is a short segment of DNA which contains many (up to ~20) restriction sites - a standard feature of engineered plasmids. Restriction sites within an MCS are typically unique, occurring only once within a given plasmid.Plant breeders' rights: Plant breeders' rights (PBR), also known as plant variety rights (PVR), are rights granted to the breeder of a new variety of plant that give the breeder exclusive control over the propagating material (including seed, cuttings, divisions, tissue culture) and harvested material (cut flowers, fruit, foliage) of a new variety for a number of years.Coles PhillipsCanadian Renewable Fuels Association: The Canadian Renewable Fuels Association (CRFA) is a non-profit organization in Canada, created in 1984. Its stated purpose is to "promote renewable fuels for transportation through consumer awareness and government liaison activities", and its membership includes "representatives from all levels of the ethanol and biodiesel industry", including agricultural associations and producers of ethanol and biodiesel.Unnatural Selection (The Outer Limits)IndicaxanthinList of strains of Escherichia coli: Escherichia coli is a well studied bacterium that was first identified by Theodor Escherich, after whom it was later named.Surface modification of biomaterials with proteins: Biomaterials are materials that are used in contact with biological systems. Biocompatibility and applicability of surface modification with current uses of metallic, polymeric and ceramic biomaterials allow alteration of properties to enhance performance in a biological environment while retaining bulk properties of the desired device.Symmetry element: A symmetry element is a point of reference about which symmetry operations can take place. In particular, symmetry elements can be centers of inversion, axes of rotation and mirror planes.Triparental mating: Triparental mating is a form of Bacterial conjugation where a conjugative plasmid present in one bacterial strain assists the transfer of a mobilizable plasmid present in a second bacterial strain into a third bacterial strain. Plasmids are introduced into bacteria for such purposes as transformation, cloning, or transposon mutagenesis.Agricultural engineering: Agricultural engineering in forestryProtein primary structure: The primary structure of a peptide or protein is the linear sequence of its amino acid structural units, and partly comprises its overall biomolecular structure. By convention, the primary structure of a protein is reported starting from the amino-terminal (N) end to the carboxyl-terminal (C) end.D-xylose reductase: D-xylose reductase (, XylR, XyrA, msXR, dsXR, monospecific xylose reductase, dual specific xylose reductase, NAD(P)H-dependent xylose reductase, xylose reductase) is an enzyme with system name xylitol:NAD(P)+ oxidoreductase. This enzyme catalyses the following chemical reactionLactic acid fermentationFlux (metabolism): Flux, or metabolic flux is the rate of turnover of molecules through a metabolic pathway. Flux is regulated by the enzymes involved in a pathway.Ligation-independent cloning: Ligation-independent cloning (LIC) is a form of molecular cloning that is able to be performed without the use of restriction endonucleases or DNA ligase. This allows genes that have restriction sites to be cloned without worry of chopping up the insert.Mannosylfructose-phosphate synthase: Mannosylfructose-phosphate synthase (, mannosylfructose-6-phosphate synthase, MFPS) is an enzyme with system name GDP-mannose:D-fructose-6-phosphate 2-alpha-D-mannosyltransferase. This enzyme catalyses the following chemical reactionOutline of chemical engineering: The following outline is provided as an overview of and topical guide to chemical engineering:Stromule: A stromule is a microscopic structure found in plant cells. Stromules (stroma-filled tubules) are highly dynamic structures extending from the surface of all plastid types, including proplastids, chloroplasts, etioplasts, leucoplasts, amyloplasts, and chromoplasts.Streptomyces peucetius: Streptomyces peucetius ATCC 27952Nicotiana glauca: Nicotiana glauca is a species of wild tobacco known by the common name tree tobacco. Its leaves are attached to the stalk by petioles (many other Nicotiana species have sessile leaves), and its leaves and stems are neither [nor sticky like Nicotiana tabacum].Biopesticide: Biopesticides, a contraction of 'biological pesticides', include several types of pest management intervention: through predatory, parasitic, or chemical relationships. The term has been associated historically with biological control - and by implication - the manipulation of living organisms.Recombination (cosmology): In cosmology, recombination refers to the epoch at which charged electrons and protons first became bound to form electrically neutral hydrogen atoms.Note that the term recombination is a misnomer, considering that it represents the first time that electrically neutral hydrogen formed.Pyruvate decarboxylase: Pyruvate decarboxylase is a homotetrameric enzyme () that catalyses the decarboxylation of pyruvic acid to acetaldehyde and carbon dioxide in the cytoplasm of prokaryotes, and in the cytoplasm and mitochondria of eukaryotes. It is also called 2-oxo-acid carboxylase, alpha-ketoacid carboxylase, and pyruvic decarboxylase.Conditional gene knockout: ==Conditional gene knockout==Ferric uptake regulator family: In molecular biology, the ferric uptake regulator (FUR) family of proteins includes metal ion uptake regulator proteins. These are responsible for controlling the intracellular concentration of iron in many bacteria.Squamosa promoter binding protein: The SQUAMOSA promoter binding protein-like (SBP or SPL) family of transcription factors are defined by a plant-specific DNA-binding domain. The founding member of the family was identified based on its specific in vitro binding to the promoter of the snapdragon SQUAMOSA gene.Breeding for drought stress toleranceConiferyl aldehydeReaction coordinatePlant lipid transfer proteinsParaHox: The ParaHox gene cluster is an array of homeobox genes (involved in morphogenesis, the regulation of patterns of anatomical development) from the Gsx, Xlox (Pdx) and Cdx gene families.Silent mutation: Silent mutations are mutations in DNA that do not significantly alter the phenotype of the organism in which they occur. Silent mutations can occur in non-coding regions (outside of genes or within introns), or they may occur within exons.Tomato seed oil: Tomato seed oil is a vegetable oil extracted from the seeds of tomatoes.DNA sequencer: A DNA sequencer is a scientific instrument used to automate the DNA sequencing process. Given a sample of DNA, a DNA sequencer is used to determine the order of the four bases: G (guanine), C (cytosine), A (adenine) and T (thymine).Synthetic genomics: Synthetic genomics is a nascent field of synthetic biology that uses aspects of genetic modification on pre-existing life forms with the intent of producing some product or desired behavior on the part of the life form so created.Weedy rice: Weedy rice, also known as red rice, is a variety of rice (Oryza) that produces far fewer grains per plant than cultivated rice and is therefore considered a pest. The name "weedy rice" is used for all types and variations of rice which show some characteristic features of cultivated rice and grow as weeds in commercial rice fields.Matrix model: == Mathematics and physics ==Porosity: Porosity or void fraction is a measure of the void (i.e.RhizobiaPhotosynthesis: Photosynthesis is a process used by plants and other organisms to convert light energy, normally from the Sun, into chemical energy that can be later released to fuel the organisms' activities. This chemical energy is stored in carbohydrate molecules, such as sugars, which are synthesized from carbon dioxide and water – hence the name photosynthesis, from the Greek [phōs, "light", and σύνθεσις], synthesis, "putting together".DNA condensation: DNA condensation refers to the process of compacting DNA molecules in vitro or in vivo. Mechanistic details of DNA packing are essential for its functioning in the process of gene regulation in living systems.BiodegradationScottish Centre for Regenerative Medicine: The Scottish Centre for Regenerative Medicine (SCRM) is a stem cell research centre at the University of Edinburgh in Scotland, dedicated to the study and development of new regenerative treatments for human diseases. The £54 million facility is part of a total £600 million joint investment in stem cell biology and medicine by the Scottish Government and the University of Edinburgh.BrittlenessBioreactorZinc fingerDeletion (genetics)Polyester resin: Polyester resins are unsaturated synthetic resins formed by the reaction of dibasic organic acids and polyhydric alcohols. Polyester resins are used in sheet moulding compound, bulk moulding compound and the toner of laser printers.PollenChilalo Agricultural Development Union: Chilalo Agricultural Development Union (CADU) is the first comprehensive package project established in Arsi Zone, Oromia Region, Ethiopia to modernize traditional subsistence agriculture. The major components of the package programmes include fertilizers, ameliorated seeds, farm credits, marketing facilities, better tools and implements, and improved storage facilities.Branching order of bacterial phyla (Gupta, 2001): There are several models of the Branching order of bacterial phyla, one of these was proposed in 2001 by Gupta based on conserved indels or protein, termed "protein signatures", an alternative approach to molecular phylogeny. Some problematic exceptions and conflicts are present to these conserved indels, however, they are in agreement with several groupings of classes and phyla.Burst kinetics: Burst kinetics is a form of enzyme kinetics that refers to an initial high velocity of enzymatic turnover when adding enzyme to substrate. This initial period of high velocity product formation is referred to as the "Burst Phase".Fungicide use in the United States: A more accurate title for this page would be "Common plant pathogens to food crops in the United States".GAI (Arabidopsis thaliana gene)List of sequenced eukaryotic genomesHuman embryonic stem cells clinical trials: ==Human Embryonic Stem Cell Clinical Trials==Planktothrix: Planktothrix is a genus of filamentous cyanobacteria (often called blue-green algae). P.GC box: In molecular biology, a GC box is a distinct pattern of nucleotides found in the promoter region of some eukaryotic genes upstream of the TATA box and approximately 110 bases upstream from the transcription initiation site. It has a consensus sequence GGGCGG which is position dependent and orientation independent.CS-BLASTCitrine (colour): Citrine is a colour], the most common reference for which is certain coloured varieties of [[quartz which are a medium deep shade of golden yellow. Citrine has been summarized at various times as yellow, greenish-yellow, brownish yellow or orange.Polyaniline nanofibers

(1/3961) Antisense RNA strategies for metabolic engineering of Clostridium acetobutylicum.

We examined the effectiveness of antisense RNA (as RNA) strategies for metabolic engineering of Clostridium acetobutylicum. Strain ATCC 824(pRD4) was developed to produce a 102-nucleotide asRNA with 87% complementarity to the butyrate kinase (BK) gene. Strain ATCC 824(pRD4) exhibited 85 to 90% lower BK and acetate kinase specific activities than the control strain. Strain ATCC 824(pRD4) also exhibited 45 to 50% lower phosphotransbutyrylase (PTB) and phosphotransacetylase specific activities than the control strain. This strain exhibited earlier induction of solventogenesis, which resulted in 50 and 35% higher final concentrations of acetone and butanol, respectively, than the concentrations in the control. Strain ATCC 824(pRD1) was developed to putatively produce a 698-nucleotide asRNA with 96% complementarity to the PTB gene. Strain ATCC 824(pRD1) exhibited 70 and 80% lower PTB and BK activities, respectively, than the control exhibited. It also exhibited 300% higher levels of a lactate dehydrogenase activity than the control exhibited. The growth yields of ATCC 824(pRD1) were 28% less than the growth yields of the control. While the levels of acids were not affected in ATCC 824(pRD1) fermentations, the acetone and butanol concentrations were 96 and 75% lower, respectively, than the concentrations in the control fermentations. The lower level of solvent production by ATCC 824(pRD1) was compensated for by approximately 100-fold higher levels of lactate production. The lack of any significant impact on butyrate formation fluxes by the lower PTB and BK levels suggests that butyrate formation fluxes are not controlled by the levels of the butyrate formation enzymes.  (+info)

(2/3961) Enhanced bioaccumulation of heavy metal ions by bacterial cells due to surface display of short metal binding peptides.

Metal binding peptides of sequences Gly-His-His-Pro-His-Gly (named HP) and Gly-Cys-Gly-Cys-Pro-Cys-Gly-Cys-Gly (named CP) were genetically engineered into LamB protein and expressed in Escherichia coli. The Cd2+-to-HP and Cd2+-to-CP stoichiometries of peptides were 1:1 and 3:1, respectively. Hybrid LamB proteins were found to be properly folded in the outer membrane of E. coli. Isolated cell envelopes of E. coli bearing newly added metal binding peptides showed an up to 1.8-fold increase in Cd2+ binding capacity. The bioaccumulation of Cd2+, Cu2+, and Zn2+ by E. coli was evaluated. Surface display of CP multiplied the ability of E. coli to bind Cd2+ from growth medium fourfold. Display of HP peptide did not contribute to an increase in the accumulation of Cu2+ and Zn2+. However, Cu2+ ceased contribution of HP for Cd2+ accumulation, probably due to the strong binding of Cu2+ to HP. Thus, considering the cooperation of cell structures with inserted peptides, the relative affinities of metal binding peptide and, for example, the cell wall to metal ion should be taken into account in the rational design of peptide sequences possessing specificity for a particular metal.  (+info)

(3/3961) Metabolic engineering of a 1,2-propanediol pathway in Escherichia coli.

1,2-Propanediol (1,2-PD) is a major commodity chemical that is currently derived from propylene, a nonrenewable resource. A goal of our research is to develop fermentation routes to 1,2-PD from renewable resources. Here we report the production of enantiomerically pure R-1,2-PD from glucose in Escherichia coli expressing NADH-linked glycerol dehydrogenase genes (E. coli gldA or Klebsiella pneumoniae dhaD). We also show that E. coli overexpressing the E. coli methylglyoxal synthase gene (mgs) produced 1,2-PD. The expression of either glycerol dehydrogenase or methylglyoxal synthase resulted in the anaerobic production of approximately 0.25 g of 1,2-PD per liter. R-1,2-PD production was further improved to 0.7 g of 1,2-PD per liter when methylglyoxal synthase and glycerol dehydrogenase (gldA) were coexpressed. In vitro studies indicated that the route to R-1,2-PD involved the reduction of methylglyoxal to R-lactaldehyde by the recombinant glycerol dehydrogenase and the reduction of R-lactaldehyde to R-1, 2-PD by a native E. coli activity. We expect that R-1,2-PD production can be significantly improved through further metabolic and bioprocess engineering.  (+info)

(4/3961) Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel "unnatural" natural products.

The structures of complex polyketide natural products, such as erythromycin, are programmed by multifunctional polyketide synthases (PKSs) that contain modular arrangements of functional domains. The colinearity between the activities of modular PKS domains and structure of the polyketide product portends the generation of novel organic compounds-"unnatural" natural products-by genetic manipulation. We have engineered the erythromycin polyketide synthase genes to effect combinatorial alterations of catalytic activities in the biosynthetic pathway, generating a library of >50 macrolides that would be impractical to produce by chemical methods. The library includes examples of analogs with one, two, and three altered carbon centers of the polyketide products. The manipulation of multiple biosynthetic steps in a PKS is an important milestone toward the goal of producing large libraries of unnatural natural products for biological and pharmaceutical applications.  (+info)

(5/3961) E-CELL: software environment for whole-cell simulation.

MOTIVATION: Genome sequencing projects and further systematic functional analyses of complete gene sets are producing an unprecedented mass of molecular information for a wide range of model organisms. This provides us with a detailed account of the cell with which we may begin to build models for simulating intracellular molecular processes to predict the dynamic behavior of living cells. Previous work in biochemical and genetic simulation has isolated well-characterized pathways for detailed analysis, but methods for building integrative models of the cell that incorporate gene regulation, metabolism and signaling have not been established. We, therefore, were motivated to develop a software environment for building such integrative models based on gene sets, and running simulations to conduct experiments in silico. RESULTS: E-CELL, a modeling and simulation environment for biochemical and genetic processes, has been developed. The E-CELL system allows a user to define functions of proteins, protein-protein interactions, protein-DNA interactions, regulation of gene expression and other features of cellular metabolism, as a set of reaction rules. E-CELL simulates cell behavior by numerically integrating the differential equations described implicitly in these reaction rules. The user can observe, through a computer display, dynamic changes in concentrations of proteins, protein complexes and other chemical compounds in the cell. Using this software, we constructed a model of a hypothetical cell with only 127 genes sufficient for transcription, translation, energy production and phospholipid synthesis. Most of the genes are taken from Mycoplasma genitalium, the organism having the smallest known chromosome, whose complete 580 kb genome sequence was determined at TIGR in 1995. We discuss future applications of the E-CELL system with special respect to genome engineering. AVAILABILITY: The E-CELL software is available upon request. SUPPLEMENTARY INFORMATION: The complete list of rules of the developed cell model with kinetic parameters can be obtained via our web site at: http://e-cell.org/.  (+info)

(6/3961) Yellow fever/Japanese encephalitis chimeric viruses: construction and biological properties.

A system has been developed for generating chimeric yellow fever/Japanese encephalitis (YF/JE) viruses from cDNA templates encoding the structural proteins prM and E of JE virus within the backbone of a molecular clone of the YF17D strain. Chimeric viruses incorporating the proteins of two JE strains, SA14-14-2 (human vaccine strain) and JE Nakayama (JE-N [virulent mouse brain-passaged strain]), were studied in cell culture and laboratory mice. The JE envelope protein (E) retained antigenic and biological properties when expressed with its prM protein together with the YF capsid; however, viable chimeric viruses incorporating the entire JE structural region (C-prM-E) could not be obtained. YF/JE(prM-E) chimeric viruses grew efficiently in cells of vertebrate or mosquito origin compared to the parental viruses. The YF/JE SA14-14-2 virus was unable to kill young adult mice by intracerebral challenge, even at doses of 10(6) PFU. In contrast, the YF/JE-N virus was neurovirulent, but the phenotype resembled parental YF virus rather than JE-N. Ten predicted amino acid differences distinguish the JE E proteins of the two chimeric viruses, therefore implicating one or more residues as virus-specific determinants of mouse neurovirulence in this chimeric system. This study indicates the feasibility of expressing protective antigens of JE virus in the context of a live, attenuated flavivirus vaccine strain (YF17D) and also establishes a genetic system for investigating the molecular basis for neurovirulence determinants encoded within the JE E protein.  (+info)

(7/3961) A small catalytic RNA motif with Diels-Alderase activity.

BACKGROUND: The 'RNA world' hypothesis requires that RNA be able to catalyze a wide variety of chemical reactions. In vitro selection from combinatorial RNA libraries has been used to identify several catalytic activities, most of which have resulted in a self-modification of RNA at one of its constituents. The formation of carbon-carbon bonds is considered an essential prerequisite for a complex metabolism based on RNA. RESULTS: We describe the selection and characterization of new ribozymes that catalyze carbon-carbon bond formation by Diels-Alder reaction of a biotinylated maleimide with an RNA-tethered anthracene. Secondary structure analysis identified a 49-nucleotide RNA motif that accelerates the reaction about 20,000-fold. The motif has only 11 conserved nucleotides that are present in most of the selected sequences. The ribozyme motif is remarkably adaptable with respect to cofactor and metal-ion requirements. The motif was also re-engineered to give a 38-mer RNA that can act as a 'true' catalyst on short external substrate oligonucleotide-anthracene conjugates. CONCLUSIONS: We have identified a small, highly abundant RNA motif that can solve the complex task of forming two carbon-carbon bonds between two reactants in trans, a catalytic capacity useful for creating prebiotically relevant molecules. This is the smallest and fastest RNA catalyst for carbon-carbon bond formation reported to date.  (+info)

(8/3961) Heterologous expression of alkene monooxygenase from Rhodococcus rhodochrous B-276.

Alkene monooxygenase (AMO) from Rhodococcus rhodochrous (formerly Nocardia corallina) B-276 is a three-component enzyme system encoded by the four-gene operon amoABCD. AMO catalyses the stereoselective epoxygenation of aliphatic alkenes, yielding primarily R enantiomers. The presumed site of alkene oxygenation is a dinuclear iron centre similar to that in the soluble methane monooxygenases of methanotrophic bacteria, to which AMO exhibits a significant degree of amino acid sequence identity. The AMO complex was not expressed in Escherichia coli, at least partly because that host did not produce all of the AMO polypeptides. Expression of AMO was achieved in Streptomyces lividans by cloning the AMO genes into the thiostrepton-inducible expression plasmid pIJ6021. No background of AMO activity was detected in S. lividans cells without amoABCD and expression of AMO activity, at a level comparable to that from wild-type R. rhodochrous B-276, coincided with appearance of the AMO subunits. Recombinant AMO activity in cell-free extracts of S. lividans was stimulated by the addition of NADH and produced R-epoxypropane with comparable enantiomeric excess to AMO purified from the original organism. Although the whole AMO complex could not be expressed in E. coli, the functional coupling protein (AmoB) and reductase (AmoD) were expressed individually in E. coli as fusions with glutathione S-transferase. The expression systems described here now allow structure/function studies on AMO to be carried out by site-directed mutagenesis.  (+info)


Is there any treatment or medicine to cure AUTISM? What about stem cells or genetic engineering?


Are there some research in place? What about new techniques like steam cells, new drugs, genetic engineering? What about alternative medicine?
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Makes you wonder what's wrong with so many kids being diagnosed with this disease lately.  No cure, just therapy over the years and ongoing support as adults.


How do you all feel about GENETIC ENGINEERING?


Genetic engineering in babies, to cure diseases (and the side effects) and in food?
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I think it should be legal because the government is wasting their time trying to stop it from happening when it is going to happen anyway.


How goes genetic engineering help cure illnesses and disease's such as parkinsons?


How is gentic engineering is used to help human beings
examples of genetic engineering being used relating to illness and disease's
does* its supposed to say soz typo
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lol - sounds like homework i did last year =) not too sure - something to do with being able to insert a functioning aleal from one ok person into the sufferer. Basic principle = good aleal = better than bad one


How might genetic engineering be used in the battle against "germs" and disease?


I needed help on this question for my science class. Genetic engineering involves changing DNA molecules.
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They will be able to manipulate genes, take 'em out, alter them.  For instance, they have now found the gene that causes shyness!  True! They really have! They would have found it earlier, but it was hiding behind another gene.


How many of you would use GENETIC ENGINEERING for your children?


Eugenics and genetic engineering will one day be realized. When this happens what is the likelyhood that you would use genetic engineering to alter your child for the better?

Would you make him/her: taller?
                                          smarter?
                                          change in eye/hair colour?
                                          music ability?

What would you most likely do?

When do you think it will be available?

And HONESTLY, would you use it on your future kids?
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No. I don't believe in it. 

My husband and I really want a daughter, but there is no way we would go to the point where we would decide everything about our children.

They come out of the womb perfectly made for US and BY us. Why would we want to change that ?


What do you you think about Genetic Engineering?


Do you think genetic engineering is good or bad to do?
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It's a great thing and will lead to longer and healthier lives.


genetic engineering in mankind like dogs cats etc did it cause the plague?


Some scholars say that we earthlings are all one gene pool and that overbreeding and genetic engineering weakened our genetic inheritance and our immune systems, thus causing plague to and other diseases to bring about the massive death toll of the black plague, and the "galloping consumption" or white death of influenza.in the 16th and 17th centuries...
maybe profiteering scientists have been around for ages.
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Nonsense.  The plague came from bacteria harbored in rats; no one in the days of the plague knew about bacteria or where they came from.  The people in the middle ages had lots of wild ideas, like "bad air", "poisoned water wells", etc.  Read a little history about it.  There were also no antibiotics back then, which easily kills the Y. pestis bacteria if someone were to catch it today (and people still can, for e.g. it still exists in great quantities in the southwest).


What replication cycle do genetic engineers study lytic or lysogenic?


Lytic or lysogenic repljcation is studied by genetic engineers and why?
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lytic