Cluster Analysis: A set of statistical methods used to group variables or observations into strongly inter-related subgroups. In epidemiology, it may be used to analyze a closely grouped series of events or cases of disease or other health-related phenomenon with well-defined distribution patterns in relation to time or place or both.Multigene Family: A set of genes descended by duplication and variation from some ancestral gene. Such genes may be clustered together on the same chromosome or dispersed on different chromosomes. Examples of multigene families include those that encode the hemoglobins, immunoglobulins, histocompatibility antigens, actins, tubulins, keratins, collagens, heat shock proteins, salivary glue proteins, chorion proteins, cuticle proteins, yolk proteins, and phaseolins, as well as histones, ribosomal RNA, and transfer RNA genes. The latter three are examples of reiterated genes, where hundreds of identical genes are present in a tandem array. (King & Stanfield, A Dictionary of Genetics, 4th ed)Gene Expression Profiling: The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.Oligonucleotide Array Sequence Analysis: Hybridization of a nucleic acid sample to a very large set of OLIGONUCLEOTIDE PROBES, which have been attached individually in columns and rows to a solid support, to determine a BASE SEQUENCE, or to detect variations in a gene sequence, GENE EXPRESSION, or for GENE MAPPING.Phylogeny: The relationships of groups of organisms as reflected by their genetic makeup.Principal Component Analysis: Mathematical procedure that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Random Amplified Polymorphic DNA Technique: Technique that utilizes low-stringency polymerase chain reaction (PCR) amplification with single primers of arbitrary sequence to generate strain-specific arrays of anonymous DNA fragments. RAPD technique may be used to determine taxonomic identity, assess kinship relationships, analyze mixed genome samples, and create specific probes.Discriminant Analysis: A statistical analytic technique used with discrete dependent variables, concerned with separating sets of observed values and allocating new values. It is sometimes used instead of regression analysis.Genetic Variation: Genotypic differences observed among individuals in a population.Space-Time Clustering: A statistically significant excess of cases of a disease, occurring within a limited space-time continuum.DNA Fingerprinting: A technique for identifying individuals of a species that is based on the uniqueness of their DNA sequence. Uniqueness is determined by identifying which combination of allelic variations occur in the individual at a statistically relevant number of different loci. In forensic studies, RESTRICTION FRAGMENT LENGTH POLYMORPHISM of multiple, highly polymorphic VNTR LOCI or MICROSATELLITE REPEAT loci are analyzed. The number of loci used for the profile depends on the ALLELE FREQUENCY in the population.Sequence Analysis, DNA: A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.Algorithms: A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.DNA, Bacterial: Deoxyribonucleic acid that makes up the genetic material of bacteria.Bacterial Typing Techniques: Procedures for identifying types and strains of bacteria. The most frequently employed typing systems are BACTERIOPHAGE TYPING and SEROTYPING as well as bacteriocin typing and biotyping.Cluster Headache: A primary headache disorder that is characterized by severe, strictly unilateral PAIN which is orbital, supraorbital, temporal or in any combination of these sites, lasting 15-180 min. occurring 1 to 8 times a day. The attacks are associated with one or more of the following, all of which are ipsilateral: conjunctival injection, lacrimation, nasal congestion, rhinorrhea, facial SWEATING, eyelid EDEMA, and miosis. (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)Genotype: The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Iron-Sulfur Proteins: A group of proteins possessing only the iron-sulfur complex as the prosthetic group. These proteins participate in all major pathways of electron transport: photosynthesis, respiration, hydroxylation and bacterial hydrogen and nitrogen fixation.Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Geography: The science dealing with the earth and its life, especially the description of land, sea, and air and the distribution of plant and animal life, including humanity and human industries with reference to the mutual relations of these elements. (From Webster, 3d ed)Amplified Fragment Length Polymorphism Analysis: The detection of RESTRICTION FRAGMENT LENGTH POLYMORPHISMS by selective PCR amplification of restriction fragments derived from genomic DNA followed by electrophoretic analysis of the amplified restriction fragments.Polymerase Chain Reaction: In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.Genes, Bacterial: The functional hereditary units of BACTERIA.Species Specificity: The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.RNA, Ribosomal, 16S: Constituent of 30S subunit prokaryotic ribosomes containing 1600 nucleotides and 21 proteins. 16S rRNA is involved in initiation of polypeptide synthesis.Software: Sequential operating programs and data which instruct the functioning of a digital computer.Data Interpretation, Statistical: Application of statistical procedures to analyze specific observed or assumed facts from a particular study.Bacterial Proteins: Proteins found in any species of bacterium.Polymorphism, Restriction Fragment Length: Variation occurring within a species in the presence or length of DNA fragment generated by a specific endonuclease at a specific site in the genome. Such variations are generated by mutations that create or abolish recognition sites for these enzymes or change the length of the fragment.Computational Biology: A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.Sequence Alignment: The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.Models, Statistical: Statistical formulations or analyses which, when applied to data and found to fit the data, are then used to verify the assumptions and parameters used in the analysis. Examples of statistical models are the linear model, binomial model, polynomial model, two-parameter model, etc.Genetic Markers: A phenotypically recognizable genetic trait which can be used to identify a genetic locus, a linkage group, or a recombination event.Classification: The systematic arrangement of entities in any field into categories classes based on common characteristics such as properties, morphology, subject matter, etc.Pattern Recognition, Automated: In INFORMATION RETRIEVAL, machine-sensing or identification of visible patterns (shapes, forms, and configurations). (Harrod's Librarians' Glossary, 7th ed)Dental Fissures: Deep grooves or clefts in the surface of teeth equivalent to class 1 cavities in Black's classification of dental caries.Microsatellite Repeats: A variety of simple repeat sequences that are distributed throughout the GENOME. They are characterized by a short repeat unit of 2-8 basepairs that is repeated up to 100 times. They are also known as short tandem repeats (STRs).Factor Analysis, Statistical: A set of statistical methods for analyzing the correlations among several variables in order to estimate the number of fundamental dimensions that underlie the observed data and to describe and measure those dimensions. It is used frequently in the development of scoring systems for rating scales and questionnaires.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Analysis of Variance: A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.Molecular Epidemiology: The application of molecular biology to the answering of epidemiological questions. The examination of patterns of changes in DNA to implicate particular carcinogens and the use of molecular markers to predict which individuals are at highest risk for a disease are common examples.Spatio-Temporal Analysis: Techniques which study entities using their topological, geometric, or geographic properties and include the dimension of time in the analysis.Sequence Homology, Amino Acid: The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.DNA, Plant: Deoxyribonucleic acid that makes up the genetic material of plants.Electrophoresis, Gel, Pulsed-Field: Gel electrophoresis in which the direction of the electric field is changed periodically. This technique is similar to other electrophoretic methods normally used to separate double-stranded DNA molecules ranging in size up to tens of thousands of base-pairs. However, by alternating the electric field direction one is able to separate DNA molecules up to several million base-pairs in length.Questionnaires: Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.Evolution, Molecular: The process of cumulative change at the level of DNA; RNA; and PROTEINS, over successive generations.Expressed Sequence Tags: Partial cDNA (DNA, COMPLEMENTARY) sequences that are unique to the cDNAs from which they were derived.DNA Primers: Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.DNA, Ribosomal: DNA sequences encoding RIBOSOMAL RNA and the segments of DNA separating the individual ribosomal RNA genes, referred to as RIBOSOMAL SPACER DNA.Models, Genetic: Theoretical representations that simulate the behavior or activity of genetic processes or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.Electrophoresis, Starch Gel: Electrophoresis in which a starch gel (a mixture of amylose and amylopectin) is used as the diffusion medium.Ecotype: Geographic variety, population, or race, within a species, that is genetically adapted to a particular habitat. An ecotype typically exhibits phenotypic differences but is capable of interbreeding with other ecotypes.Genetic Structures: The biological objects that contain genetic information and that are involved in transmitting genetically encoded traits from one organism to another.Computer Simulation: Computer-based representation of physical systems and phenomena such as chemical processes.China: A country spanning from central Asia to the Pacific Ocean.BrazilPolymorphism, Genetic: The regular and simultaneous occurrence in a single interbreeding population of two or more discontinuous genotypes. The concept includes differences in genotypes ranging in size from a single nucleotide site (POLYMORPHISM, SINGLE NUCLEOTIDE) to large nucleotide sequences visible at a chromosomal level.Statistics as Topic: The science and art of collecting, summarizing, and analyzing data that are subject to random variation. The term is also applied to the data themselves and to the summarization of the data.Cloning, Molecular: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.Topography, Medical: The systematic surveying, mapping, charting, and description of specific geographical sites, with reference to the physical features that were presumed to influence health and disease. Medical topography should be differentiated from EPIDEMIOLOGY in that the former emphasizes geography whereas the latter emphasizes disease outbreaks.Minisatellite Repeats: Tandem arrays of moderately repetitive, short (10-60 bases) DNA sequences which are found dispersed throughout the GENOME, at the ends of chromosomes (TELOMERES), and clustered near telomeres. Their degree of repetition is two to several hundred at each locus. Loci number in the thousands but each locus shows a distinctive repeat unit.Bacteria: One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.Bayes Theorem: A theorem in probability theory named for Thomas Bayes (1702-1761). In epidemiology, it is used to obtain the probability of disease in a group of people with some characteristic on the basis of the overall rate of that disease and of the likelihood of that characteristic in healthy and diseased individuals. The most familiar application is in clinical decision analysis where it is used for estimating the probability of a particular diagnosis given the appearance of some symptoms or test result.Escherichia coli: A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.Databases, Genetic: Databases devoted to knowledge about specific genes and gene products.Gene Expression Regulation: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.Geographic Information Systems: Computer systems capable of assembling, storing, manipulating, and displaying geographically referenced information, i.e. data identified according to their locations.Models, Molecular: Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.Transcription, Genetic: The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION.Gene Expression Regulation, Neoplastic: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in neoplastic tissue.Neoplasms, Plasma Cell: Neoplasms associated with a proliferation of a single clone of PLASMA CELLS and characterized by the secretion of PARAPROTEINS.Chromosome Mapping: Any method used for determining the location of and relative distances between genes on a chromosome.Serotyping: Process of determining and distinguishing species of bacteria or viruses based on antigens they share.Reverse Transcriptase Polymerase Chain Reaction: A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.Microarray Analysis: The simultaneous analysis, on a microchip, of multiple samples or targets arranged in an array format.Catastrophization: Cognitive and emotional processes encompassing magnification of pain-related stimuli, feelings of helplessness, and a generally pessimistic orientation.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Protein Array Analysis: Ligand-binding assays that measure protein-protein, protein-small molecule, or protein-nucleic acid interactions using a very large set of capturing molecules, i.e., those attached separately on a solid support, to measure the presence or interaction of target molecules in the sample.Multivariate Analysis: A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.Proteomics: The systematic study of the complete complement of proteins (PROTEOME) of organisms.Food Habits: Acquired or learned food preferences.Fruit: The fleshy or dry ripened ovary of a plant, enclosing the seed or seeds.RNA, Bacterial: Ribonucleic acid in bacteria having regulatory and catalytic roles as well as involvement in protein synthesis.Nucleic Acid Hybridization: Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)Soil Microbiology: The presence of bacteria, viruses, and fungi in the soil. This term is not restricted to pathogenic organisms.Gene Expression: The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.Molecular Typing: Using MOLECULAR BIOLOGY techniques, such as DNA SEQUENCE ANALYSIS; PULSED-FIELD GEL ELECTROPHORESIS; and DNA FINGERPRINTING, to identify, classify, and compare organisms and their subtypes.Gene Library: A large collection of DNA fragments cloned (CLONING, MOLECULAR) from a given organism, tissue, organ, or cell type. It may contain complete genomic sequences (GENOMIC LIBRARY) or complementary DNA sequences, the latter being formed from messenger RNA and lacking intron sequences.Cross-Sectional Studies: Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.Demography: Statistical interpretation and description of a population with reference to distribution, composition, or structure.Chorda Tympani Nerve: A branch of the facial (7th cranial) nerve which passes through the middle ear and continues through the petrotympanic fissure. The chorda tympani nerve carries taste sensation from the anterior two-thirds of the tongue and conveys parasympathetic efferents to the salivary glands.Databases, Factual: Extensive collections, reputedly complete, of facts and data garnered from material of a specialized subject area and made available for analysis and application. The collection can be automated by various contemporary methods for retrieval. The concept should be differentiated from DATABASES, BIBLIOGRAPHIC which is restricted to collections of bibliographic references.Transcriptome: The pattern of GENE EXPRESSION at the level of genetic transcription in a specific organism or under specific circumstances in specific cells.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Models, Biological: Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.Artificial Intelligence: Theory and development of COMPUTER SYSTEMS which perform tasks that normally require human intelligence. Such tasks may include speech recognition, LEARNING; VISUAL PERCEPTION; MATHEMATICAL COMPUTING; reasoning, PROBLEM SOLVING, DECISION-MAKING, and translation of language.Ecosystem: A functional system which includes the organisms of a natural community together with their environment. (McGraw Hill Dictionary of Scientific and Technical Terms, 4th ed)Diet: Regular course of eating and drinking adopted by a person or animal.Proteome: The protein complement of an organism coded for by its genome.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Phylogeography: A field of study concerned with the principles and processes governing the geographic distributions of genealogical lineages, especially those within and among closely related species. (Avise, J.C., Phylogeography: The History and Formation of Species. Harvard University Press, 2000)Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Cohort Studies: Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.Binding Sites: The parts of a macromolecule that directly participate in its specific combination with another molecule.DNA, Ribosomal Spacer: The intergenic DNA segments that are between the ribosomal RNA genes (internal transcribed spacers) and between the tandemly repeated units of rDNA (external transcribed spacers and nontranscribed spacers).Genetics, Population: The discipline studying genetic composition of populations and effects of factors such as GENETIC SELECTION, population size, MUTATION, migration, and GENETIC DRIFT on the frequencies of various GENOTYPES and PHENOTYPES using a variety of GENETIC TECHNIQUES.Microdissection: The performance of dissections with the aid of a microscope.Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.United StatesDisease Outbreaks: Sudden increase in the incidence of a disease. The concept includes EPIDEMICS and PANDEMICS.Alleles: Variant forms of the same gene, occupying the same locus on homologous CHROMOSOMES, and governing the variants in production of the same gene product.Spectroscopy, Fourier Transform Infrared: A spectroscopic technique in which a range of wavelengths is presented simultaneously with an interferometer and the spectrum is mathematically derived from the pattern thus obtained.Genomics: The systematic study of the complete DNA sequences (GENOME) of organisms.Biodiversity: The variety of all native living organisms and their various forms and interrelationships.Tumor Markers, Biological: Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.Genes, Plant: The functional hereditary units of PLANTS.Sequence Homology, Nucleic Acid: The sequential correspondence of nucleotides in one nucleic acid molecule with those of another nucleic acid molecule. Sequence homology is an indication of the genetic relatedness of different organisms and gene function.Rivers: Large natural streams of FRESH WATER formed by converging tributaries and which empty into a body of water (lake or ocean).Gene Expression Regulation, Bacterial: Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in bacteria.Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)Least-Squares Analysis: A principle of estimation in which the estimates of a set of parameters in a statistical model are those quantities minimizing the sum of squared differences between the observed values of a dependent variable and the values predicted by the model.Protein Structure, Secondary: The level of protein structure in which regular hydrogen-bond interactions within contiguous stretches of polypeptide chain give rise to alpha helices, beta strands (which align to form beta sheets) or other types of coils. This is the first folding level of protein conformation.Pain Measurement: Scales, questionnaires, tests, and other methods used to assess pain severity and duration in patients or experimental animals to aid in diagnosis, therapy, and physiological studies.Conserved Sequence: A sequence of amino acids in a polypeptide or of nucleotides in DNA or RNA that is similar across multiple species. A known set of conserved sequences is represented by a CONSENSUS SEQUENCE. AMINO ACID MOTIFS are often composed of conserved sequences.DNA, Fungal: Deoxyribonucleic acid that makes up the genetic material of fungi.Pseudomonas: A genus of gram-negative, aerobic, rod-shaped bacteria widely distributed in nature. Some species are pathogenic for humans, animals, and plants.Sequence Analysis, Protein: A process that includes the determination of AMINO ACID SEQUENCE of a protein (or peptide, oligopeptide or peptide fragment) and the information analysis of the sequence.Plant Diseases: Diseases of plants.ItalyProtein Conformation: The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).Enzymes: Biological molecules that possess catalytic activity. They may occur naturally or be synthetically created. Enzymes are usually proteins, however CATALYTIC RNA and CATALYTIC DNA molecules have also been identified.DNA, Complementary: Single-stranded complementary DNA synthesized from an RNA template by the action of RNA-dependent DNA polymerase. cDNA (i.e., complementary DNA, not circular DNA, not C-DNA) is used in a variety of molecular cloning experiments as well as serving as a specific hybridization probe.Cattle: Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.Electron Spin Resonance Spectroscopy: A technique applicable to the wide variety of substances which exhibit paramagnetism because of the magnetic moments of unpaired electrons. The spectra are useful for detection and identification, for determination of electron structure, for study of interactions between molecules, and for measurement of nuclear spins and moments. (From McGraw-Hill Encyclopedia of Science and Technology, 7th edition) Electron nuclear double resonance (ENDOR) spectroscopy is a variant of the technique which can give enhanced resolution. Electron spin resonance analysis can now be used in vivo, including imaging applications such as MAGNETIC RESONANCE IMAGING.Restriction Mapping: Use of restriction endonucleases to analyze and generate a physical map of genomes, genes, or other segments of DNA.Image Processing, Computer-Assisted: A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.Proteins: Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.Ferredoxins: Iron-containing proteins that transfer electrons, usually at a low potential, to flavoproteins; the iron is not present as in heme. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)Socioeconomic Factors: Social and economic factors that characterize the individual or group within the social structure.Fibromyalgia: A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95)Taste: The ability to detect chemicals through gustatory receptors in the mouth, including those on the TONGUE; the PALATE; the PHARYNX; and the EPIGLOTTIS.Agriculture: The science, art or practice of cultivating soil, producing crops, and raising livestock.

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... and NORMIX analysis assuming equal covariance matrices for each group. It is shown that the normix solution differs from the ... data on the Strong Vocational Interest Blank profiles of 113 occupational groups are analyzed by three different clustering ... Descriptors : (*APTITUDE TESTS, STATISTICAL ANALYSIS), CORRELATION TECHNIQUES, NAVAL PERSONNEL, PERSONNEL MANAGEMENT. Subject ... and NORMIX analysis assuming equal covariance matrices for each group. It is shown that the normix solution differs
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http://gis.harvard.edu/services/project-consultation/project-resume/us-cluster-mapping
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http://orbit.dtu.dk/en/publications/functional-analysis-and-heterologous-expression-of-polyketides-gene-cluster
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This study analyses 35 manufacturing clusters from the Annual Survey of Industrial Firms (ASIFs) Database of China. Findings ... Chinese Manufacturing Clusters Panorama. Presentation by Jie Guo, Ph.D. candidate in School of Government at Peking University ... Industrial cluster is an important strategy choice for regional economic development and competitiveness. Methods of research ... The Center for Geographic Analysis, a member of the Institute for Quantitative Social Science (IQSS), 1737 Cambridge
http://gis.harvard.edu/events/seminar-series/chinese-manufacturing-clusters-panorama
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... and skills that you need to collect and analyze system performance data from NetApp storage systems that are running clustered ... Professionals who manage NetApp storage systems and would like a deeper understanding of Clustered Data ONTAP system ... Describe how data flows through the network and protocol layers of clustered Data ONTAP ... and skills that you need to collect and analyze system performance data from NetApp storage systems that are running clustered ...
http://hbfites.com/index.php/netapp-training?id=515:performance-analysis-on-clustered-data-ontap&=
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ANALYSIS: MoM poses next question for Boeing presence in Washington cluster. *18 aprile 2017 ... Registration gives you instant free access to FlightGlobal's news, in-depth analysis, insight and opinion from our global team ... ANALYSIS: RAF Typhoons impress on Romanian air policing duty. *11 agosto 2017 ...
http://naviganti.org/esteri/analysis-mom-poses-next-question-for-boeing-presence-in-washington-cluster/
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Archaeological data analysis and fuzzy clustering. Archaeometry, 51, pp. 1035-1054. Full text not available from this ...
http://irep.ntu.ac.uk/id/eprint/2619/
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Harnessing clusters for high performance computation of gene expression microarray comparative analysis (deposited 14-08-2017) ... Harnessing clusters for high performance computation of gene expression microarray comparative analysis. Church, Philip, Wong, ... Harnessing clusters for high performance computation of gene expression microarray comparative analysis ... Harnessing clusters for high performance computation of gene expression microarray comparative analysis. In Hsu, Ching-Hsien, ...
http://dro.deakin.edu.au/view/DU:30034364
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www.statisticssolutions.com/cluster-analysis-2. What is the Cluster Analysis? The Cluster Analysis is an explorative analysis ... en.wikipedia.org/wiki/Cluster_analysis. Cluster analysis or clustering is the task of grouping a set of objects in such a way ... www.statsoft.com/Textbook/Cluster-Analysis. In fact, cluster analysis is not as much a typical statistical test as it is a ' ... Cluster analysis. - Grouping a set of data objects into clusters. • Clustering is unsupervised classification: no ...
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http://biorxiv.org/content/early/2017/03/16/116566
*  CDC | TB | Genotyping | Chap 2 | Genotyping Used to Improve Contact & Cluster Investigations
Genotyping Used to Improve Contact Cluster Investigations. Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to site content Skip directly to page options. Guide to the Application of Genotyping to Tuberculosis Prevention and Control. Tuberculosis Genotyping Case Studies: How TB Programs Have Used Genotyping Genotyping Used to Improve Contact and Cluster Investigations The Massachusetts Department of Public Health recently reported on their universal genotyping program and provided evidence that genotyping strengthened both their contact and cluster investigations Miller 2002. Relationship or location of presumed transmission for 25 patients with suspected epidemiologic links detected during contact investigations that were not confirmed by subsequent genotyping results — Massachusetts, 1996–2000. From 1996 through 2000, Massachusetts used routine contact investigations to identify 92 epidemiologic links between 984 persons with TB. In ...
http://cdc.gov/tb/programs/genotyping/Chap2/2_TBCase_6Improve_Contact.htm
*  Where global solutions are shaped for you | Disarmament | Convention on Cluster Munitions
UNOG - The United Nations Office at Geneva I am a ... Conference on Disarmament. Convention on Cluster Munitions. Taking Forward Multilateral Nuclear Disarmament Negotiations. Other Issues Related to Disarmament. Conference on Disarmament. Convention on Cluster Munitions. Taking Forward Multilateral Nuclear Disarmament Negotiations. Other Issues Related to Disarmament. Convention on Cluster Munitions. The Convention on Cluster Munitions was concluded by the Dublin Diplomatic Conference on Cluster Munitions at Dublin on 30 May 2008. The Convention is the result of the Oslo-process, a diplomatic process that included States, civil society, the International Committee of the Red Cross as well as the United Nations. Following up on the progress made at the Lima Conference May 2007, the Viena Conference December 2007, and the Wellington Conference February 2008, in May 2008 107 participating states agreed to adopt the text of the new convention at the Dublin Conference on ...
http://unog.ch/80256EE600585943/(httpPages)/F27A2B84309E0C5AC12574F70036F176?OpenDocument
*  [Beowulf] SGI to offer Windows on clusters
sgi to offer windows on clusters sgi to offer windows on clusters jim lux james p lux at jpl nasa gov wed jan pst previous message sgi to offer windows on clusters next message sgi to offer windows on clusters messages sorted by at am joe landman wrote mikhail kuzminsky wrote in message from mikael fredriksson mike at etek chalmers se mon jan this article sgi to offer windows on clusters might be worth reading http www computerworld com action article do command viewarticlebasic articleid source nlt pm nlid any comments in any case it s bad news sgi has solid reputation in hpc and university world and may be somebody will be tempted but it s interesting w which prices sgi will sell their clusters hope that the price will be much more higher than for sgi linux clusters my understanding of pricing for the windows portion is that it adds as an os usd to each node so for a node machine this is an extra k usd tax added on doesn t include the absolutely necessary ...
http://beowulf.org/pipermail/beowulf/2007-January/017196.html
*  Results for 2012 CRL Under 15 Country Championships - Foster - FOX SPORTS PULSE
2012 CRL Under 13's Country Cup Final 2012 CRL Under 18 Regional Championships 2012 Under 14 Cluster 6, 7, 16 & Illaw 2012 Under 14 Cluster Group 9, 10, 11 & 20 2012 Under 13 Cluster 6, 7, 16 & Illaw 2012 Under 13 Cluster Group 9, 10, 11, & 20 2011 CRL Tier 1 Senior Championships 2011 CRL Under 16 Cup Country Championships 2011 CRL Tier 2 Senior Championships 2011 CRL Under 16's Trophy Country Championships 2011 CRL Under 16's Plate Country Championships 2011 CRL Under 18 Championship 2011 CRL Under 15's Cup Country Championships 2011 CRL Under 15's Trophy Country Championships 2011 CRL Under 15's Plate Country Championships 2011 Under 14's Cluster Groups 1, 2, 3, 18 2011 Under 14's Cluster Groups 4, 14, 19, 21 2011 Under 14 Cluster 6,7,16 Illaw 2011 Under 14's Cluster Groups 9, 10, 11 & 20 2011 Under 14 Cluster Cen Coast, New & Maitland 2011 Under 13's Cluster Groups 1, 2, 3, 18 2011 Under 13's Cluster Groups 4, 14, 19, 21 2011 ...
http://foxsportspulse.com/comp_info.cgi?a=ROUND&round=-1&client=7-4973-0-218119-0&pool=1
*  [Beowulf] SGI to offer Windows on clusters
SGI to offer Windows on clusters. SGI to offer Windows on clusters Douglas Eadline deadline at eadline.org. Previous message: SGI to offer Windows on clusters Next message: Sun Releases Fortress Implementation Messages sorted by:. My understanding of pricing for the windows portion is that it adds as an OS $500USD to each node. So for a 32 node machine, this is an extra $16k USD tax added on. Doesn't include the absolutely necessary antivirus, anti-spyware, ... Probably wouldn't be that expensive, especially if you boot the same image on all nodes of the cluster. Update one, update all. Is this Windows clustering version, too. I just finished writing an article about the Tyan PSC for Linux magazine. It has 10 quad-core Xeons, GigE, Infiniband, a KVM all in small 21 x 14 x 28 52.7 cm x 35.6 cm x 70 cm package it weighs 150 pounds. They are selling a optional five node version of WCCS for $2,345 $469/node About WCCS. I believe MS is concentrating on bundled applications to ...
http://clustermonkey.net/pipermail/beowulf/2007-January/041555.html
*  2 projects tagged "cluster analysis" – Freecode
... Effective 2014-06-18 Freecode is no longer being updated content may be stale. Learn More. Articles. Browse Projects by Tag. Blog. Sites. Mac OS X. Mobile. Unix. 2 projects tagged cluster analysis. Tags. cluster analysis 2. Data Mining 1. heuristics 1. machine classif.. Diagnostics 1. Clustering 1. SysAdmin 1. hierarchical cl.. 1 Licenses. GPLv2 1. Apache 2.0 1. Programming languages. SQLite 3 1. Bash shell scri.. HTML 1. Java 1. Operating systems. Linux 1. Mac OS X 1. Project Name. Updated 24 Aug 2013. ClodHopper. P op. 32.34. V it. ClodHopper is a Java library for high-performance clustering of numerical data. It contains clustering implementations such as K-Means, K-Means++, X-Means, G-Means, Fuzzy C-Means, Jarvis-Patrick, and various forms of hierarchical clustering. ClodHopper's clustering implementations take advantage of the host system's concurrent processing ability to speed clustering. The data structures are also ...
http://freecode.com/tags/cluster-analysis?page=1&with=&without=34485
*  2 projects tagged "cluster analysis" – Freecode
... Effective 2014-06-18 Freecode is no longer being updated content may be stale. Learn More. Articles. Browse Projects by Tag. Blog. Sites. Mac OS X. Mobile. Unix. 2 projects tagged cluster analysis. Tags. cluster analysis 2. Data Mining 1. heuristics 1. machine classif.. Diagnostics 1. Clustering 1. SysAdmin 1. hierarchical cl.. 1 Licenses. GPLv2 1. Apache 2.0 1. Programming languages. SQLite 3 1. Bash shell scri.. HTML 1. Java 1. Operating systems. Linux 1. Mac OS X 1. Project Name. Updated 24 Aug 2013. ClodHopper. P op. 32.34. V it. ClodHopper is a Java library for high-performance clustering of numerical data. It contains clustering implementations such as K-Means, K-Means++, X-Means, G-Means, Fuzzy C-Means, Jarvis-Patrick, and various forms of hierarchical clustering. ClodHopper's clustering implementations take advantage of the host system's concurrent processing ability to speed clustering. The data structures are also ...
http://freecode.com/tags/cluster-analysis?sort=name&with=&without=
*  Single-particle and cluster levels in 107,108,109Sn populated in the decay of 107,108,109Sb
... all Scitation. AIP Conference Proceedings. AIP Publishing AVS: Science Technology of Materials, Interfaces, and Processing Acoustical Society of America American Association of Physicists in Medicine American Association of Physics Teachers American Crystallographic Association, Inc. Chinese Physical Society Chinese Society of Theoretical and Applied Mechanics Laser Institute of America The Society of Rheology. Email: *. Email: *. I'm an author/editor/contributor to this publication. EVENT EVENTLOG PORTALID aip /PORTALID SESSIONID 1xescxedol049.x-aip-live-02 /SESSIONID USERAGENT CCBot/2.0 http://commoncrawl.org/faq/ /USERAGENT IDENTITYID guest /IDENTITYID IDENTITY LIST guest /IDENTITY LIST IPADDRESS 54.83.67.158 /IPADDRESS EVENTTYPE PERSONALISATION /EVENTTYPE CREATEDON 1443957259266 /CREATEDON /EVENTLOG EVENTLOGPROPERTY ITEM ID http://aip.metastore.ingenta.com/content/aip/proceeding/aipcp/10.1063/1.57350 /ITEM ID TYPE recommendtolibrary /TYPE /EVENTLOGPROPERTY /EVENT. Invalid site public key. AIP ...
http://scitation.aip.org/content/aip/proceeding/aipcp/10.1063/1.57350
*  Welcome to Focali Focali
Forests, climate and livelihoods are interconnected Forests can play a vital part for both climate- and poverty issues; in reducing the emissions of greenhouse gases and as a source of income for poor people that depend on the forest for their livelihood. Multifunctional landscapes Many Focali researchers focus on synergies and trade-offs between different land-uses in the landscape, such as interactions between forests and agriculture. It is aimed at reducing emissions of carbon dioxide from forests. Welcome to Focali Focali Forest, Climate, and Livelihood research network is a Swedish research network focusing on forest / bio-energy, climate change and poverty issues. Sep 29, 2015 A new publication by Jenny Friman within our thematic collaboration with SIANI. New brief: Addressing food security climate change with agroforestry, what are the policy options. Sep 29, 2015 A new publication by Eskil Mattsson within our thematic collaboration with SIANI. Water, Forests and People Aug 31, 2015 The Swedish Water ...
http://focali.se/en
*  Carolina Digital Repository - GSEA of murine pathway models versus five human subtypes.
carolina digital repository gsea of murine pathway models versus five human subtypes carolina digital repository home browse browse collections browse departments about about the repository frequently asked questions cdr policies and guidelines outreach and partnerships how to contribute material to the cdr technology overview cdr blog contact contact us request access login advanced search back to results previous next doc gsea of murine pathway models versus five human subtypes date deposited download folders collections biomed central identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors parent collection biomed central title gsea of murine pathway models versus five human subtypes identifier uuid ce c eb a aa db c export metadata oai dublin core ...
https://cdr.lib.unc.edu/record?id=uuid:453162ce-2c79-47eb-a322-7798aa4db4c8
*  Carolina Digital Repository - (a)
carolina digital repository a carolina digital repository home browse browse collections browse departments about about the repository frequently asked questions cdr policies and guidelines outreach and partnerships how to contribute material to the cdr technology overview cdr blog contact contact us request access login advanced search back to results previous next pdf a date deposited download view folders collections biomed central identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors parent collection biomed central title a identifier uuid c cc af b be a ab dcfac f cf export metadata oai dublin core premis events related items neighbors in this collection folder pdf this analysis was used to determine a human pdf this unsupervised cluster analysis is based upon doc gsea of murine pathway models versus clinical er pdf a pdf samples are colored according to mouse model from tiff histological characterization of six ...
https://cdr.lib.unc.edu/record?id=uuid:0c6cc0af-63b4-4be2-a6ab-dcfac52f92cf
*  .. Dallaire calls for transparency as cluster bomb bill moves forward .. Related Stories: .. electi
Dallaire left Wednesday’s Standing Senate Committee on Foreign Affairs and International Trade meeting frustrated due to a misunderstanding during the amendment reading on Bill S-10, an Act to Implement the Convention on Cluster Munitions. But confusion during the reading of Dallaire’s two-part amendment to Section 11 of the bill led to a heated exchange during the meeting. Section 11 would legally exempt Canadian forces from Article 21 of the Convention, which prohibits member states from using cluster munitions in joint military operations with states not party to the Convention. Dallaire’s amendments called for a complete ban of the use of cluster munitions — even in joint operations. Andreychuk and the other Conservative committee members were not available for comment Tuesday. While Dallaire applauds the effort to ratify the Convention on Cluster Munitions, which Canada signed in 2008, he said the exemptions outlined in S-10 defeat the purpose of the convention, which ...
http://ipolitics.ca/2012/11/13/dallaire-calls-for-transparency-as-cluster-bomb-bill-moves-forward/
*  Newest 'cluster' Questions - Unix & Linux Stack Exchange
Newest 'cluster' Questions - Unix & Linux Stack Exchange. Unix Linux. Help Center Detailed answers to any questions you might have. Unix Linux Questions. Tagged Questions info newest frequent votes active unanswered. 0 votes. 1 answer. 14 views. shell-script cluster asked Sep 20 at 16:31. 4 0 votes. 0 answers. 31 views. cluster batch-jobs cluster-ssh asked Sep 18 at 20:26. 2 votes. 1 answer. 23 views. bash ssh cluster asked Sep 18 at 15:39. 1 answer. 35 views. python scheduling cluster external-hdd asked Sep 15 at 16:58. 4 -1 votes. 1 answer. 58 views. ubuntu 64bit cluster 32bit asked Sep 14 at 21:06. 0 answers. 53 views. centos rhel cluster pacemaker asked Sep 1 at 6:41. 4 0 votes. 0 answers. 8 views. 1 answer. 32 views. python performance top cluster load asked Aug 7 at 21:28. 0 votes. 1 answer. 112 views. Cluster is up, every ... linux kernel cluster distributed-filesystem asked May 10 at 2:25. How to benchmark ...
http://unix.stackexchange.com/questions/tagged/cluster
*  HCV infection cluster help
On the definition of "clusters" and "related sequences" in the HCV database The "exclude related" function selects only the first sequence usually the one with the lowest accession number from each cluster of epidemiologically related sequences from one genomic region, and discards the rest. To get an overview of which clusters have been defined in the database, select "Clusters" in the "Other fields" pulldown menu and type an underscore character in the search field. This will list all defined clusters in the database, and the patients and sequences they are defined on. To select a single cluster for example the cluster associated with patient "Recip 1", a recipient of an infected blood transfusion, type "Recip 1" in the Patient Code field, select "Cluster name" in the Other Fields pulldown and put a star * in the search field; this will list all clusters this patient is a part of. The "Exclude related" function only works when the search has ...
http://hcv.lanl.gov/content/sequence/HelpDocs/cluster-help.html
*  www.biomedcentral.com - Figure
www biomedcentral com figure figure the graph shows a subnetwork of proteins linked to stress responses in p falciparum it was detected using the mine plug in for cytoscape which uses an agglomerative approach to search the topology of large networks for significant clusters the visualization is as for figure lilburn et al bmc genomics suppl s doi s s
http://biomedcentral.com/1471-2164/12/S5/S9/figure/F3
*  Page 2 | Hitting the Cluster Wall - A Study in Cluster Optimization | Projects | Features
Hitting the Cluster Wall - A Study in Cluster Optimization. Site News. Projects Hitting the Cluster Wall - A Study in Cluster Optimization. Article Index Hitting the Cluster Wall - A Study in Cluster Optimization. The GNU/Atlas library and the fact that we are using TCP based MPI libraries. As mentioned, TCP use buffers. Previous tests using Netpipe TCP showed a 29 useconds latency and a 66 MBytes/sec throughput. Before, seeing the effect on HPL, it may be useful to see the difference between GAMMA-MPI, LAM/MPI, and MPICH1. Fortunately, the Netpipe benchmark has an MPI version. Figure One: Throughput vs block size for MPI-GAMMA, LAM/MPI, and MPICH1. Table One: NETPIPE Latency Results MPICH48 MPI Version Latency LAM 41. Figure Two: Latency Signature for MPI-GAMMA, LAM/MPI, and MPICH1. There was a problem with memory space, however. In the case of HPL, the problem size is smaller and thus the less GFLOPS are possible. None the less, it was possible to run a problem ...
http://clustermonkey.net/Projects/hitting-the-cluster-wall-a-study-in-cluster-optimization/Page-2.html
*  Instrument Cluster Store | Instrument Cluster Replacement & Repair
instrument cluster store instrument cluster replacement repair call us at repair cloning service faq customer service need a replacement instrument cluster please call us at we can help you search our inventory the nation s largest to find the correct one for your application repair we provide only the most reliable speedometer repair solutions including speedometer calibration and mileage correction services to ensure that your gauge is working properly and accurately learn more cloning service we provide full cloning services for vehicles that hold the immobilizer inside the cluster cloning involves transferring the immobilizer data from you old cluster to your replacement cluster learn more the ics advantage buy with confidence we offer the following advantages free ground shipping on all orders day warranty on every purchase orders generally ship within hours all clusters are tested and approved before selling top notch customer service to help with your ...
http://instrumentclusterstore.com/
*  CRUISE CONTROLE - Jeep - FORUM Marques
... The instrument cluster will turn on the ETC indicator for the following reasons: ² Bulb Test - Each time the ignition switch is turned to the On position the ETC indicator is illuminated for about 15 seconds. ² ETC Lamp-On Message - Each time the cluster receives a lamp-on message from the PCM, the ETC indicator will be illuminated. ² Communication Error - If the cluster receives no lamp-on or lamp-off message from the PCM for 20 consecutive seconds, the Malfunction Indicator Lamp MIL is illuminated by the instrument cluster. The MIL remains controlled and illuminated by the cluster until a valid ETC indicator lamp-on or lamp-off message is received from the PCM. ² Actuator Test - Each time the cluster is put through the actuator test, the ETC indicator will be turned on, then off again during the bulb check portion of the test to confirm the functionality of the LED and the cluster control circuitry. The actuator test illumination of the ETC indicator is ...
http://forum-auto.com/marques/jeep/sujet2837.htm
*  IC 2391
ic ic infobox open cluster name ic image epoch j constellation vela class open cluster ra dec ic also known as the omicron velorum cluster or caldwell is an open cluster in the constellation vela the persian astronomer al sufi may have first described it about it was found by abbe lacaille and cataloged as lac ii the cluster is about light year s away from earth and can be seen with the naked eye it contains about stars with a total visual magnitude of spread out along arcminutes the cluster appears to be about the same age as the open cluster ic and has a lithium depletion boundary age of about million years see also omicron velorum references external links entry for ic list of open clusters entry for ic category open clusters category vela constellation b
https://en.wikipedia.org/wiki/IC_2391
*  ParaHox
... The 'ParaHox' gene cluster is an array of homeobox genes involved in morphogenesis, the regulation of patterns of anatomical development from the Gsx, Xlox Pdx and Cdx gene families. Regulatory gene cluster. These genes were first shown to be arranged into a physically-linked chromosomal cluster in amphioxus, an invertebrate with a single member of each of the three gene families. 1 All the ParaHox genes in the amphioxus genome are therefore in the ParaHox gene cluster. In contrast, the human genome has six ParaHox genes GSX1, GSX2, PDX1, CDX1, CDX2, CDX4, of which three genes GSX1, PDX1 =IPF1, CDX2 are physically linked to form a human ParaHox gene cluster on chromosome 13. 2 Mouse has a homologous ParaHox gene cluster on chromosome 5. The other three human ParaHox genes are remnants from duplicated ParaHox gene clusters that were generated in the 2R genome duplications at the base of vertebrate evolution. Some vertebrates, notably chondrichthyan fish ...
https://en.wikipedia.org/wiki/ParaHox
*  Gene cluster
Because there was only a single copy of the gene, they could not undergo mutations which would potentially result in new genes; however, gene duplication allows essential genes to undergo mutations in the duplicated copy, which would ultimately give rise to new genes over the course of evolution. 3 Mutations in the duplicated copy were tolerated because the original copy contained genetic information for the essential gene's function. 4 Over a short span of time, the new genetic information exhibited by the duplicated copy of the essential gene would not serve a practical advantage; however, over a long, evolutionary time period, the genetic information in the duplicated copy may undergo additional and drastic mutations in which the proteins of the duplicated gene served a different role than those of the original essential gene. When gene duplication occurs to produce a gene cluster, one or multiple genes may be duplicated at once. In the case of the Hox gene, a shared ancestral ProtoHox ...
https://en.wikipedia.org/wiki/Gene_cluster
*  ABI gene family member 3
abi gene family member abi gene family member abi gene family member abi also known as new molecule including sh nesh is a protein that in humans is encoded by the abi gene function this gene encodes a member of an adaptor protein family members of this family encode proteins containing a homeobox homology domain proline rich region and src homology sh domain the encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration this may be accomplished through interaction with p activated kinases references further reading
https://en.wikipedia.org/wiki/ABI_gene_family_member_3
*  Anti -ABI3BP, ID (ABI3BP, NESHBP, TARSH, Target of Nesh-SH3, ABI gene family member 3-binding protei
anti abi bp id abi bp neshbp tarsh target of nesh sh abi gene family member binding protein nesh binding protein azide free hrp united states biological login email password forgot your password new user remember me home distributors technical about register antibodies biochemicals culture media custom services growth factors bioassay kits lectins molecular biology serum tissues protocols newsletter about us contact you are here home antibodies antibodies binding proteins anti abi bp id abi bp neshbp tarsh target of nesh sh abi gene family member binding protein nesh binding protein azide free hrp anti abi bp id abi bp neshbp tarsh target of nesh sh abi gene family member binding protein nesh binding protein azide free hrp pricing for pricing information usa customers sign in outside usa please contact your distributor for pricing specifications clone host grade applications polyclonal rabbit affinity purified e b the function of this protein remains unknown catalog hrp applications suitable for use in ...
http://usbio.net/item/031501-HRP
*  Sodium in biology
Function of sodium ions Human water and salt balance. Calcium ion Ca 2+ also tastes salty and sometimes bitter to some people but, like potassium, can trigger other tastes. Sodium is the primary cation positive ion in extracellular fluids in animals and humans. These fluids, such as blood plasma and extracellular fluids in other tissues, bathe cells and carry out transport functions for nutrients and wastes. Human water and salt balance. Although the system for maintaining optimal salt and water balance in the body is a complex one,. 14 electronic-book ISBN 978-94-007-5561-1 electronic- one of the primary ways in which the human body keeps track of loss of body water is that osmoreceptor s in the hypothalamus sense a balance of sodium and water concentration in extracellular fluids. Relative loss of body water will cause sodium concentration to rise higher than normal, a condition known as hypernatremia. Conversely, an excess of body water caused by drinking will result in too little sodium in the blood ...
https://en.wikipedia.org/wiki/Sodium_in_biology
*  Gene expression profiling reveals early cellular responses to intracellular magnetic labeling with s
... uperparamagnetic iron oxide nanoparticles. - PubMed - NCBI Warning: The NCBI web site requires JavaScript to function. NCBI. BLAST Basic Local Alignment Search Tool. BLAST Stand-alone. BLAST Basic Local Alignment Search Tool. BLAST Stand-alone. Conserved Domain Search Service CD Search. Conserved Domain Search Service CD Search. All Genes Expression Resources... PubMed. PubMed Central PMC. Search database All Databases Assembly BioProject BioSample BioSystems Books ClinVar Clone Conserved Domains dbGaP dbVar Epigenomics EST Gene Genome GEO DataSets GEO Profiles GSS GTR HomoloGene MedGen MeSH NCBI Web Site NLM Catalog Nucleotide OMIM PMC PopSet Probe Protein Protein Clusters PubChem BioAssay PubChem Compound PubChem Substance PubMed PubMed Health SNP SRA Structure Taxonomy ToolKit ToolKitAll ToolKitBook UniGene Search term. 1 selected item: 20373404 Format Summary Summary text Abstract Abstract text MEDLINE XML PMID List. Gene expression profiling reveals early cellular responses to intracellular ...
http://ncbi.nlm.nih.gov/pubmed/20373404
*  High Throughput Gene Expression/Biomarker Core Laboratory | UMASS Medical School
High Throughput Gene Expression/Biomarker Core Laboratory. UMASS Medical School. Main Menu Home Page. Meet the Staff. Instrumentation. Possible Applications. Sample Submission. Rates. Why This Core. Utility Links. Open/Close Menu. Search. Advanced Search. Search. Advanced Search. HT Gene Expression. Skip Navigation. Home Page. Meet the Staff. Instrumentation. Possible Applications. Sample Submission. Rates. Why This Core. . Contact Us Co-Director: Kahraman Tanriverdi, PhD Phone: 508-856-6962 kahraman.tanriverdi@umassmed.edu www.umassmed.edu/htcore. High Throughput Gene Expression/Biomarker Core Laboratory. The High Throughput Gene Expression/Biomarker Core Laboratory run by Drs. Tanriverdi and Freedman provides High Throughput/Rapid Gene Expression and Complete miRNA profiling analysis by using gold standard qRT-PCR with the combination of custom Integrated Fluidic Circuit IFC technology from Fluidigm South San Francisco, CA. Also, high-throughput SNP and multi-plate immunoassay services are ...
http://umassmed.edu/htcore
*  Gene expression profiling reveals reproducible human lung adenocarcinoma subtypes in multiple indepe
... ndent patient cohorts. Our Approach Areas of Focus History Leadership Who is Broad Partner Institutions Artist-in-Residence Media Center. Press Room News from the Broad Photos for Journalists Spotlight: Ebola Spotlight: CRISPR BroadMinded Blog Video Library For the Scientific Community. Scientific Publications Science Data Software. Scientific Publications Science Data Software. News & Publications:Scientific Publications Gene expression profiling reveals reproducible human lung adenocarcinoma subtypes in multiple independent patient cohorts. Read More / View Supplemental Materials. Scientific Publications Back to Publications Gene expression profiling reveals reproducible human lung adenocarcinoma subtypes in multiple independent patient cohorts. Tumor subtypes were distinguishable by many hundreds of genes, and lists generated in one cohort were predictive of tumor subtypes in the two other cohorts. Most notably, bronchioid tumors were correlated with improved survival in early-stage disease, whereas ...
http://broadinstitute.org/publications/broad837
*  Genome-wide gene expression profiling and a forward genetic screen show that differential expression
... of the sodium ion transporter Ena21 contributes to the differential tolerance of Candida albicans and Candida dubliniensis to osmotic stress. . Home. Submit. Login. View Item. TARA. School of Dental Sciences. Dental Science. Dental Science Scholarly Publications. View Item. TARA. School of Dental Sciences. Dental Science. Dental Science Scholarly Publications View Item. JavaScript is disabled for your browser. Some features of this site may not work without it. Search TARA. This Collection. Advanced Search. Browse. All of TARA. Academic/Research Units Collections Titles Authors Date of Publication Subjects Sponsor This Collection. Titles Authors Date of Publication Subjects Sponsor. Statistics. View Google Analytics Statistics. Genome-wide gene expression profiling and a forward genetic screen show that differential expression of the sodium ion transporter Ena21 contributes to the differential tolerance of Candida albicans and Candida dubliniensis to osmotic stress. File Type:. PDF. Item Type:. Journal ...
http://tara.tcd.ie/xmlui/handle/2262/29626
*  ARS | Publication request: WHOLE-GENOME EXPRESSION PROFILING DEFINES THE HRPL REGULON OF PSEUDOMONAS
Publication request: WHOLE-GENOME EXPRESSION PROFILING DEFINES THE HRPL REGULON OF PSEUDOMONAS SYRINGAE PV. TOMATO DC3000, ALLOWS DE NOVO RECONSTRUCTION OF THE HRP CIS ELEMENT, AND IDENTIFIES NOVEL CO-REGULATED GENES ARS : Research. ARS Office of International Research Programs. Title: WHOLE-GENOME EXPRESSION PROFILING DEFINES THE HRPL REGULON OF PSEUDOMONAS SYRINGAE PV. TOMATO DC3000, ALLOWS DE NOVO RECONSTRUCTION OF THE HRP CIS ELEMENT, AND IDENTIFIES NOVEL CO-REGULATED GENES Authors. Whole-genome expression profiling defines the hrpl regulon of pseudomonas syringae pv. tomato dc3000, allows de novo reconstruction of the hrp cis element, and identifies novel co-regulated genes. tomato DC3000 is a model bacterial pathogen of tomato and Arabidopsis that deploys a type III secretion system a highly sophisticated secretion system used to introduce specific bacterial proteins called effectors into the plant host cells to disrupt plant cell defenses during pathogenesis. Accordingly, elucidation of the regulatory ...
https://ars.usda.gov/research/publications/publications.htm?SEQ_NO_115=196114
*  High Throughput Gene Expression | Possible Application | UMASS Medical School
High Throughput Gene Expression. Meet the Staff. Advanced Search. Advanced Search. HT Gene Expression. Meet the Staff. HT Gene Expression. Contact Us Co-Director: Kahraman Tanriverdi, PhD Phone: 508-856-6962 kahraman.tanriverdi@umassmed.edu www.umassmed.edu/htcore. HT Gene Expression. Possible Applications High-Throughput Gene Expression Analysis. Ninety-six samples can be analyzed for 96 gene expression assays in under 3 hours. Standard TaqMan SNP assays or your own primers can be used. Users may also choose to submit their genes for DELTAgene assay design service provided by Fluidigm. High-Throughput miRNA Profiling. Ninety-six or more samples can be analyzed for any miRNA assay or entire miRNA assay library 1,801 miRNA Assays in 1-5 business days. Qiagen miScript miRNA assays are provided by core. High-Throughput miRNA Inhibitor Mimic Transfection. Up to 96 miRNA inhibitor or mimic at a time can be transfected to desired cell line and up to 96 gene expression level can be analyzed in a few days ...
http://umassmed.edu/htcore/possible_applications/
*  High Throughput Gene Expression | Instrumentation | UMASS Medical School
High Throughput Gene Expression. Instrumentation. Meet the Staff. Instrumentation. Advanced Search. Advanced Search. HT Gene Expression. Meet the Staff. Instrumentation. HT Gene Expression. Instrumentation. Instrumentation. Contact Us Co-Director: Kahraman Tanriverdi, PhD Phone: 508-856-6962 kahraman.tanriverdi@umassmed.edu www.umassmed.edu/htcore. HT Gene Expression. Instrumentation. Instrumentation MagNa Lyser Instrument This instrument simplifies labor-intensive sample preparation. QIAcube Instrument The QIAcube uses QIAGEN spin columns isolation kits, enabling seamless integration of automated, low-throughput sample preparation. JANUS Automated Workstation JANUS Automated Workstation is a liquid handling robot that provides rapid pipetting with superior QC. AB 7900HT Real-Time PCR Instrument In addition to providing fast 96 well, 384 well blocks, the TaqMan Low Density Array TLDA attachment is available for pre-picked gene expression analyses. BioMark Real-Time PCR System The BioMark System provides the ...
http://umassmed.edu/htcore/instrumentation/
*  Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma
... subclasses. What is Broad. Our Approach Areas of Focus History Leadership Who is Broad Partner Institutions Artist-in-Residence Media Center. Press Room News from the Broad Photos for Journalists Spotlight: Ebola Spotlight: CRISPR BroadMinded Blog Video Library For the Scientific Community. Scientific Publications Science Data Software. Scientific Publications Science Data Software. News & Publications:Scientific Publications Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. Read More / View Supplemental Materials Somatic mutation in single human neurons tracks developmental and transcriptional history. Read More / View Supplemental Materials Linking RNA biology to lncRNAs. Read More / View Supplemental Materials Ethanol Enhances TGF-β Activity by Recruiting TGF-β Receptors from Intracellular Vesicles/Lipid Rafts/Caveolae to Non-lipid Raft Microdomains. Read More / View Supplemental Materials. Scientific Publications Back to Publications ...
https://broadinstitute.org/publications/broad902
*  Browse < ArrayExpress < EMBL-EBI
Browse ArrayExpress EMBL-EBI. Skip to local navigation. Skip to EBI global navigation menu. Skip to expanded EBI global navigation menu includes all sub-sections. Services. Training. Industry. ArrayExpress. Examples: E-MEXP-31, cancer, p53, Geuvadis Advanced. About ArrayExpress. Login. Filter search results By organism: All organisms loading options By experiment type: All assays by molecule loading options. All technologies loading options By array: All arrays loading options. E-GEOD-24551. Exon level expression profiling of colorectal cancer tissue samples. transcription profiling by array. Homo sapiens. - E-GEOD-24550. Exon level expression profiling of colorectal cancer tissue samples validation sample series. transcription profiling by array. Homo sapiens. - E-GEOD-24549. Exon level expression profiling of colorectal cancer tissue samples test sample series. transcription profiling by array. Homo sapiens. - E-GEOD-24030. ChIP-seq, transcription profiling by array. Mus musculus. - E-GEOD-24029. ...
http://ebi.ac.uk/arrayexpress/experiments/browse.html?page=1523&pagesize=25
*  Digital Gene-Expression Profiling | GEN Magazine Articles | GEN
Digital Gene-Expression Profiling. Analysis of the RNA-Seq and SCA Publication Landscape. FDA Nominee Driven by "Data, Data, Data". More GEN Exclusives ». Analysis of the RNA-Seq and SCA Publication Landscape. FDA Nominee Driven by "Data, Data, Data". More GEN Exclusives ». Advertorial: OriGene Technologies. Market & Tech An... Jobs. Login/Register. GEN Exclusives More. Analysis of the RNA-Seq and SCA Publication Landscape RNA-Seq and SCA Could Have a... Microarray-based gene-expression profiling technology hardly seems like it has been around long enough for a new approach to come along and challenge its market dominance. Yet, there is a growing sense that digital gene-expression profiling, a fully quantitative approach for gene-expression analysis, will replace microarrays in this application area. Within this emerging market sector for digital RNA counting, the methodologies and technologies are evolving so rapidly that traditional sequencing-based serial analysis of ...
http://genengnews.com/gen-articles/digital-gene-expression-profiling/2844/?page=1
*  Use of global gene expression patterns in mechanistic studies of oestrogen action in MCF7 human bre
... ast cancer cells - CentAUR. Use of global gene expression patterns in mechanistic studies of oestrogen action in MCF7 human breast cancer cells. Wordle Link RDF+XML BibTeX RIOXX2 XML RDF+N-Triples JSON Dublin Core Atom Simple Metadata Refer METS HTML Citation with IDs HTML Citation ASCII Citation OpenURL ContextObject EndNote OpenURL ContextObject in Span MODS MPEG-21 DIDL EP3 XML Dublin Core Reference Manager RDF+N3. D 2009 Use of global gene expression patterns in mechanistic studies of oestrogen action in MCF7 human breast cancer cells. Global gene expression profiling has shown that oestrogen action in MCF7 cells involves the coordinated regulation of hundreds of genes across a wide range of functional groupings and that more genes are down regulated than upregulated. Adaptation to long-term oestrogen deprivation, which results in loss of oestrogen-responsive growth, involves alterations to gene patterns not only at early time points 0-4 weeks but continuing through to later times 20-55 weeks, and ...
http://centaur.reading.ac.uk/9692/
*  BioSpace - A Strategy for Full Interrogation of Prognostic Gene Expression Patterns: Exploring th
... e Biology of Diffuse Large B Cell Lymphoma. Post Jobs. Jobs. A Strategy for Full Interrogation of Prognostic Gene Expression Patterns: Exploring the Biology of Diffuse Large B Cell Lymphoma Published: Thursday, August 04, 2011 Author: Lisa M. LeBlanc Background Gene expression profiling yields quantitative data on gene expression used to create prognostic models that accurately predict patient outcome in diffuse large B cell lymphoma DLBCL. Often, data are analyzed with genes classified by whether they fall above or below the median expression level. We sought to determine whether examining multiple cut-points might be a more powerful technique to investigate the association of gene expression with outcome. Methodology/Principal Findings We explored gene expression profiling data using variable cut-point analysis for 36 genes with reported prognostic value in DLBCL. We plotted two-group survival logrank test statistics against corresponding cut-points of the gene expression levels and smooth ...
http://biospace.com/PLos_Article.aspx?id=1582
*  DNASTAR - Gene Panel Assembly and Analysis Software | DNASTAR
DNASTAR - Gene Panel Assembly and Analysis Software. DNASTAR. DNASTAR Lasergene. Molecular Biology. Next-Gen Sequencing. Structural Biology. Clinical Research. Molecular Biology. Sanger Sequence Assembly. Sequence Alignment. Structural Biology. Epitope Prediction. Protein Sequence & Structure. Protein Structure Prediction. Structural Alignment. Next-Gen Sequencing. Automated Genome Closure. Cancer Genomics. ChIP-Seq Analysis. De Novo Genome Assembly. De Novo Transcriptome Assembly. Exome Alignment. Gene Panels. Reference Guided Genome Alignment. RNA-Seq Alignment. SNP Validation Control. Variant Analysis. Clinical Research. Cancer Genomics. Gene Panels. SUPPORT. Help. FAQs. Request Support. Supported File Formats. Technical Requirements. Tutorials. NGS Support Materials. #1 in NGS Accuracy. Genome Template Packages. Supported Sequencing Technologies. Genome Assembly. Structure Prediction. Download Free Trial. Request Educational Software. Request Quote. Request Quote. Free Trial. Gene ...
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*  Multiclass cancer diagnosis using tumor gene expression signatures | Broad Institute of MIT and Harv
Multiclass cancer diagnosis using tumor gene expression signatures. Partnerships Philanthropy Careers Contact Us. Our Approach Areas of Focus History Leadership Who is Broad Partner Institutions Artist-in-Residence Media Center. Press Room News from the Broad Photos for Journalists Spotlight: Ebola Spotlight: CRISPR BroadMinded Blog Video Library For the Scientific Community. Scientific Publications Science Data Software. Scientific Publications Science Data Software. News & Publications:Scientific Publications Multiclass cancer diagnosis using tumor gene expression signatures. Read More / View Supplemental Materials Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores. Read More / View Supplemental Materials. Scientific Publications Back to Publications Multiclass cancer diagnosis using tumor gene expression signatures. To determine whether the diagnosis of multiple common adult malignancies could be achieved purely by molecular classification, we subjected 218 tumor samples, spanning ...
https://broadinstitute.org/publications/broad900
*  PLOS Pathogens: Genome-Wide mRNA Expression Correlates of Viral Control in CD4+ T-Cells from HIV-1-I
... nfected Individuals. Journal Archive. Other Article Types. Article-Level Metrics. Journal Information. View. Sum of PLOS and PubMed Central page views and downloads. Open Access Peer-reviewed Research Article. Genome-Wide mRNA Expression Correlates of Viral Control in CD4+ T-Cells from HIV-1-Infected Individuals. Published: February 26, 2010 DOI: 10.1371/journal.ppat.1000781. Article. 2010 Genome-Wide mRNA Expression Correlates of Viral Control in CD4+ T-Cells from HIV-1-Infected Individuals. doi:10.1371/journal.ppat.1000781 Editor: Michael Emerman, Fred Hutchinson Cancer Research Center, United States of America Received: June 2, 2009; Accepted: January 20, 2010; Published: February 26, 2010 Copyright: © 2010 Rotger et al. Transcriptome analysis in CD4+ T cells from HIV-infected untreated individuals. In total, 260 genes are differentially expressed at adjusted p 0.01 in association with viral load in CD4+ T cells during in vivo HIV-1 infection. Among genes under differential expression during ...
http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1000781
*  A Randomized Phase II Trial Comparing Therapy Based on Tumor Molecular Profiling Versus Conventional
... Therapy in Patients With Refractory Cancer - Full Text View - ClinicalTrials.gov. A Randomized Phase II Trial Comparing Therapy Based on Tumor Molecular Profiling Versus Conventional Therapy in Patients With Refractory Cancer SHIVA This study is currently recruiting participants. If a molecular abnormality is identified for which an approved targeted agent is available, patients are randomized randomized between two arms: Targeted therapy based on the molecular profile Conventional therapy based on investigator's choice. Drug: Targeted therapy based on molecular profiling : Imatinib Procedure: Tumor biopsy Drug: Standard Chemotherapy Drug: Targeted therapy based on molecular profiling : Everolimus Drug: Targeted therapy based on molecular profiling : Vemurafenib Drug: Targeted therapy based on molecular profiling : Sorafenib Drug: Targeted therapy based on molecular profiling : Erlotinib Drug: Targeted therapy based on molecular profiling : Lapatinib + Trastuzumab Drug: Targeted therapy based on ...
https://clinicaltrials.gov/ct2/show/NCT01771458
*  Gene expression profiling
... Expression profiling experiments often involve measuring the relative amount of mRNA expressed in two or more experimental conditions. The simplest form of class discovery would be to list all the genes that changed by more than a certain amount between two experimental conditions. Other experiments, such as a Western blot of some of the protein products of differentially expressed genes, make conclusions based on the expression profile more persuasive, since the mRNA levels do not necessarily correlate to the amount of expressed protein. Statistical analysis. Different from the analysis on differentially expressed individual genes, another type of analysis focuses on differential expression or perturbation of pre-defined gene sets and is called gene set analysis. While the statistics may identify which gene products change under experimental conditions, making biological sense of expression profiling rests on knowing which protein each gene product makes and what function ...
https://en.wikipedia.org/wiki/Gene_expression_profiling
*  KEGG PATHWAY: Cytokine-cytokine receptor interaction - Canis familiaris (dog)
KEGG PATHWAY: Cytokine-cytokine receptor interaction - Canis familiaris dog. Cytokine-cytokine receptor interaction - Canis familiaris dog. [ Pathway menu Organism menu Pathway entry. Download KGML Show description User data mapping ]. Cytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell growth, differentiation, cell death, angiogenesis, and development and repair processes aimed at the restoration of homeostasis. Cytokines are released by various cells in the body, usually in response to an activating stimulus, and they induce responses through binding to specific receptors on the cell surface of target cells. Cytokines can be grouped by structure into different families and their receptors can likewise be grouped.
http://genome.jp/kegg-bin/show_pathway?cfa04060
*  Gene signature
... a gene signature is a group of gene s in a cell whose combined expression pattern itadani h mizuarai s kotani h can systems biology understand pathway activation gene expression signatures as surrogate markers for understanding the complexity of pathway activation curr genomics aug pmid is uniquely characteristic of a biological phenotype or medical condition liu j campen a huang s peng sb ye x palakal m dunker ak xia y li s identification of a gene signature in cell cycle pathway for breast cancer prognosis using gene expression profiling data bmc med genomics sep pmid the phenotypes that may theoretically be defined by a gene expression signature range from those that are used to differentiate between different subtypes of a disease those that predict the survival or prognosis of an individual with a disease to those that predict activation of a particular pathway ideally gene signatures can be used to select a group of patients wouters bj löwenberg b erpelinck verschueren ca van putten wl valk pj ...
https://en.wikipedia.org/wiki/Gene_signature
*  Center for Genomics and Public Health - Gene Expression Profiling in Early-Stage Breast Cancer - Gen
... e Expression Profiling in Early-Stage Breast Cancer Risk-Benefit Analysis Case Study. University of Washington Center for Genomics and Public Health. Home Training. Genetic Awareness. Genomic Applications for Public Health Video Series. Policy & Health Economics Videos. Confounding by Population Stratification. Nutrigenomics. Genetic Epidemiology Methods Video Series. Resources. Tools for Public Health Professionals. Publications. Spotlight Factsheets. Links to Other Resources. In the News. Health Topics. DNA Day. Genetics. Genomics versus Genetics. Genetic Testing: what is it. A Public Health Issue. Evidence-Based Review. EGAPP. Glossary. Links to Genetic Testing Resources. Family History & Genomics. BRFSS. BRFSS Timeline. Compilations. Links and Resources. Risk Benefit for Genetics. Risk Benefit Case Studies and Models. About Us. Director's Page. Future of Public Health Genetics. Technical Assistance. Personnel. Contact Us. Partners. The Gene Expression Profiling in Early-Stage Breast Cancer ...
http://depts.washington.edu/cgph/riskCaseGeneExprBreastCancer
*  .. Boosting Gene Expression Profiling .. !--h2>
Their research program initially focused on using the high-density Affymetrix Human Exon 1.0 ST array platform for monitoring changes in the expression levels of genes and alternative splicing events of hematopoietic cells, both at the gene and exon levels. Her team was interested in looking at the pattern and gene expression modulations in lineage-specific differentiation of CD34+ cells in vitro, noted Dr. Whole transcriptome and exome analysis on both microarrays and sequencing platforms to identify genes that are significantly up- or downregulated during cell differentiation allowed us to discover novel alternatively spliced transcripts, she further explained. Bowcock, Ph.D., professor, applied deep sequencing techniques in identifying major modifications in the changes in mRNA expression profiles of psoriasis patients. In the case of skin differentiation, miRNA gene expression analysis could reveal dramatic changes in global microRNA expression, reflecting defects in keratinocytes, immune ...
http://genengnews.com/keywordsandtools/print/1/29363/
*  Diagnosis of metastatic neoplasms: Molecular approaches for identification of tissue of origin - Res
... earchGate. Article Diagnosis of metastatic neoplasms: Molecular approaches for identification of tissue of origin. Federico Alberto Monzon. Impact Factor: 2.84. Molecular tests for tissue-of-origin determination in metastatic tumors are available and have the potential to significantly impact patient management. Cost-Effectiveness of Gene-Expression Profiling for Tumor-Site Origin. ABSTRACT: Gene-expression profiling GEP reliably supplements traditional clinicopathological information on the tissue of origin TOO in metastatic or poorly differentiated cancer. The average increase in quality-adjusted life-months was 2.7 months 95% CI 1.5-4.3, and average third-party payer costs per patient increased by $10,360 95% CI $2,982-$19,192. DOI:10.1016/j.jval.2012.09.005 3.28 Impact Factor Source Available from: Torik Ayoubi. "Several studies have already demonstrated that it is possible to use genome-wide gene expression analysis using micro-array technology in the determination of the tissue of origin of ...
http://researchgate.net/publication/41397041_Diagnosis_of_metastatic_neoplasms_Molecular_approaches_for_identification_of_tissue_of_origin
*  Gene Ontology Classifications
... Genes. Human Disease. Expression. Genes. Genes Markers Query. Batch Query. Mouse Genome Browser. Human Disease OMIM Browser. Human Disease. Expression. Gene Expression Data Query. Gene Expression Literature Query. Mouse Developmental Anatomy Browser. GO Browser. Genes Markers Query. Batch Query. Sequences. Mouse Genome Browser. Batch Query. Gene Expression Literature Query. GO Browser. Human Disease OMIM Browser. Mouse Developmental Anatomy Browser. Adult Mouse Anatomy Browser. Batch Query. Mouse Genome Browser. Batch Query. Genes Markers. Sequence Data. Gene Ontology Data. Gene Expression. Mouse Resources & Model Organism Links. Phenotypes Mutants Community Resources. Nucleic Acids Research Journal Database Summary. Tabular View GO Graph GO curators for mouse genes have assigned the following annotations to the gene product of Gm2a. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl ...
http://informatics.jax.org/go/marker/MGI:95762
*  statistics - A mathematician's confusion regarding parametric $t$ tests for gene expression data - B
statistics - A mathematician's confusion regarding parametric $t$ tests for gene expression data - Biology Stack Exchange. Biology Meta. more stack exchange communities. Stack Exchange. sign up log in tour. Help Center Detailed answers to any questions you might have. Biology Questions. Sign up. Biology Stack Exchange is a question and answer site for biology researchers, academics, and students. A mathematician's confusion regarding parametric $t$ tests for gene expression data. I'm a mathematician trying to test some things on gene expression data, and I'm thus skimming over various articles such as Sotiriou et. gene-expression statistics share. asked Oct 25 '12 at 15:10. 5 add a comment. 2 Answers 2 active oldest votes. As a computational biologist I would advise you to look specifically at bioinformatics papers if you are looking into developing new methods, since the analysis in "pure biology" papers can often be lacking and would not give you a good perspective of state-of-the-art ...
http://biology.stackexchange.com/questions/5010/a-mathematicians-confusion-regarding-parametric-t-tests-for-gene-expression-d?answertab=active
*  .. Axela Takes Over Xceed for Ziplex Automated Gene-Expression Analysis Platform
. Send to printer. GEN News Highlights : Jul 26, 2010. Axela Takes Over Xceed for Ziplex Automated Gene-Expression Analysis Platform. Firms claim combined technologies will help speed introduction of new biomarker diagnostics. Axela has acquired Toronto-based Xceed Molecular to get its hands on the latter s Ziplex gene-expression analysis platform and assays. The combined firm will retain the Axela name but move its headquarters to Xceed s facilities in Toronto. Axela says the combination of both companies technologies will provide clinical researchers with a growing suite of products for multiplexing DNA, RNA, and protein biomarker analysis, and help speed the introduction of new diagnostics. Xceed s Ziplex platform has been developed as an integrated and fully automated hybridization system for multiplex gene-expression signatures. The system hinges on Xceed s Flow-Thru Chip FTC technology for multi-analyte analysis, which is embodied in the single-use TipChip consumables that ...
http://genengnews.com/keywordsandtools/print/4/19944/
*  The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and diseas
... e. Partnerships Philanthropy Careers Contact Us. Our Approach Areas of Focus History Leadership Who is Broad Partner Institutions Artist-in-Residence Media Center. Press Room News from the Broad Photos for Journalists Spotlight: Ebola Spotlight: CRISPR BroadMinded Blog Video Library For the Scientific Community. Scientific Publications Science Data Software. Scientific Publications Science Data Software. News & Publications:Scientific Publications The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. Read More / View Supplemental Materials Ethanol Enhances TGF-β Activity by Recruiting TGF-β Receptors from Intracellular Vesicles/Lipid Rafts/Caveolae to Non-lipid Raft Microdomains. Read More / View Supplemental Materials American Diabetes Association and JDRF Research Symposium: Diabetes and the Microbiome. Read More / View Supplemental Materials. Scientific Publications Back to Publications The Connectivity Map: using gene-expression signatures to connect ...
http://broadinstitute.org/publications/broad3612
*  .. Identifying New Gene-Expression Patterns .. Analyzing Xpress
Identifying New Gene-Expression Patterns. Analyzing XpressWay Human Expression Data with OmniViz Visual Analytics Software. This evaluation is greatly aided by the provision of high-quality gene-expression data and sophisticated software tools for identifying targets with interesting expression patterns. In this article, we describe the combination of Asterand s XpressWay human gene-expression data with BioWisdom s visual analytics software, OmniViz. XpressWay gene-expression data is provided with BioWisdom annotation around gene synonyms, disease, and process information. The inclusion of disease and process information provides context to the gene-expression data, and allows the user to search for interesting targets by virtue of their functional role. Using OmniViz to analyze XpressWay data, it is possible to get an overview of the gene-expression patterns of all ~2,000 genes Figure 1, and then to quickly identify those gene-expression profiles that possess features of interest. For example, if you are ...
http://genengnews.com/keywordsandtools/print/1/12859/
*  BioSpace - Integrated Genomic and Gene Expression Profiling Identifies Two Major Genomic Circuits
... in Urothelial Carcinoma. Post Jobs. Jobs. Career Resources. Career Fairs. Company Profiles. Search Life Sciences Jobs. Integrated Genomic and Gene Expression Profiling Identifies Two Major Genomic Circuits in Urothelial Carcinoma Published: Thursday, June 07, 2012 Author: David Lindgren et al. by David Lindgren, Gottfrid Sjödahl, Martin Lauss, Johan Staaf, Gunilla Chebil, Kristina Lövgren, Sigurdur Gudjonsson, Fredrik Liedberg, Oliver Patschan, Wiking Månsson, Mårten Fernö, Mattias Höglund Similar to other malignancies, urothelial carcinoma UC is characterized by specific recurrent chromosomal aberrations and gene mutations. However, the interconnection between specific genomic alterations, and how patterns of chromosomal alterations adhere to different molecular subgroups of UC, is less clear. We applied tiling resolution array CGH to 146 cases of UC and identified a number of regions harboring recurrent focal genomic amplifications and deletions. Several potential oncogenes were included in the ...
http://biospace.com/PLos_Article.aspx?id=16203
*  This Week in Cancer Research | GenomeWeb
This Week in Cancer Research. GenomeWeb. Skip to main content. RSS Feeds Twitter LinkedIn. Business Policy. Business News Research Funding Policy Legislation Regulatory News Reimbursement. Genetic Research Gene Expression Research Epigenetics Research Proteomics Protein Research Cell Biology Research. Clinical. Molecular Diagnostics Companion Diagnostics Biomarker Discovery Validation Drug Discovery Development Clinical Sequencing Clinical Proteomics. Disease Areas. Cancer Infectious Disease Cardiovascular Disease Neurological Psychological Disease Metabolic Disease Autoimmune Disease Inherited Disease Reproductive Health. Home » This Week in Cancer Research. This Week in Cancer Research Aug 01, 2012. Premium. In Cancer Research this week, a team led by researchers at Laval University in Canada describe the molecular signature found in the lung tissue of smokers. The team carried out genome-wide gene expression profiling on normal lung tissue from 853 lung cancer patients and compared gene expression between ...
https://genomeweb.com/week-cancer-research-20
*  Systems Biology Core Laboratory - New York Medical College
Preparatory techniques: - DNA, RNA and protein extraction, purification, - RNA reverse transcription and fluorescent labeling - DNA and proteins fluorescent labeling - DNA, RNA and protein concentration NanoDrop - DNA, RNA, proteins concentration and QC Bioanalyzer - Western blotting - SpeedVac concentration of proteins, DNAs and RNAs - Controlled PCR amplification B. Hybridization of Agilent microarrays: - Whole Genome Gene Expression microarrays for 30+ species - Exon microarrays human, mouse, rat - miRNA microarrays - CGH Comparative Genomic Hybridization microarrays - CGH+SNP Single Nucleotide Polymorphism microarrays - CNV Copy Number Variant microarrays - ChIP-on-chip Chromatin ImmunoPrecipitation microarrays - DNA methylation CpG islands microarrays C. Hybridization of Illumina beadchips: - Whole Genome Expression BeadChips: human, mouse, rat - Infinium iSelect HD custom genotyping BeadChips for virtually all species - Infinium HumanMethylation450 BeadChip - Infinium HumanCytoSNP-FFPE-12 BeadChips - ...
https://nymc.edu/Research/CoreFacilitiesAndResources/SystemsBiologyCore.html
*  RNAlater® Solution Around the World | FACS Into RNAlater® Solution for Gene Profiling | Thermo Fis
RNAlater® Solution Around the World. FACS Into RNAlater® Solution for Gene Profiling. Thermo Fisher Scientific. Order Support. Custom Products & Projects. Cell Analysis. DNA & RNA Purification. Gene Expression Analysis & Genotyping. PCR. Real-Time PCR. Thermo Scientific. Thermo Scientific. Services. New Products. CaptureSelect™ Products & Services. Diagnostic Products & Services. Thermo Scientific. Air Quality & Water Analysis. Optimized Biopsy Preservation for Clinical Gene Expression and Profiling. Real-Time RT-PCR Directly from Cell Lysates: A Complete Workflow without RNA Purification. Recover High Yields of Total Nucleic Acid from Formalin-fixed, Paraffin-embedded Tissue. RNAlater Preserves Bacterial Gene Expression Profiles for Array Analysis. The Ambion RNA later Tissue Collection: RNA Stabilization Solution is an aqueous tissue storage reagent that stabilizes and protects cellular RNA in intact, unfrozen tissue samples. RNA later Solution eliminates the need to process ...
https://thermofisher.com/us/en/home/references/ambion-tech-support/rna-isolation/tech-notes/facs-into-rnalater-solution-for-gene-profiling.html
*  Carel A van Baalen - ResearchGate
... For full functionality of ResearchGate it is necessary to enable JavaScript. Here are the instructions how to enable JavaScript in your web browser. Carel A van Baalen. Erasmus MC, Rotterdam, South Holland, Netherlands. Are you Carel A van Baalen. Claim your profile. Publications 36 155.85 Total impact. Article:. DC immunotherapy in HIV-1 infection induces a major blood transcriptome shift. Anna L de Goede. Arno C Andeweg. Henk-Jan van den Ham. Maarten A Bijl. Fatiha Zaaraoui-Boutahar. Wilfred F J van IJcken. Sofie Wilgenhof. Joeri L Aerts. Rob A Gruters. Albert D M E Osterhaus. Sabine D Allard Carel A van Baalen. Brenda De Keersmaecker. Marchina E van der Ende. Kris Thielemans. Patrick Lacor. ABSTRACT: This study aimed to evaluate the effect of dendritic cell DC vaccination against HIV-1 on host gene expression profiles. Longitudinal PBMC samples were collected from participants of the DC-TRN trial for immunotherapy against HIV. Microarray-assisted gene expression profiling was performed to evaluate ...
http://researchgate.net/researcher/38566550_Carel_A_van_Baalen
*  Anti -DAB2, CT (DOC-2, Differentially-expressed Protein 2, Disabled Homolog 2, DOC2) (Biotin) - Unit
Anti -DAB2, CT DOC-2, Differentially-expressed Protein 2, Disabled Homolog 2, DOC2 Biotin - United States Biological. Login. Email. Password. Forgot your password. New User. Remember me. Home. Distributors. Technical. About. Register. Antibodies. Biochemicals. Culture Media. Custom Services. Growth Factors. Bioassay Kits. Lectins. Molecular Biology. Serum, Tissues. Protocols. Newsletter. About Us. Contact. . You are here: Home. Antibodies. Antibodies-Tumor Suppressors. Anti -DAB2, CT DOC-2, Differentially-expressed Protein 2, Disabled Homolog 2, DOC2 Biotin Anti -DAB2, CT DOC-2, Differentially-expressed Protein 2, Disabled Homolog 2, DOC2 Biotin. Pricing For pricing information, USA customers sign in. Outside USA. Please contact your distributor for pricing. Specifications Clone. Host. Grade Applications Polyclonal Rabbit Affinity Purified E B. DAB2 is the component of the CSF-1 signal transduction pathway. Catalog # D0900-19C-Biotin. Applications Suitable for use in ELISA and Western Blot. Other ...
http://usbio.net/item/D0900-19C-Biotin
*  UTHSC : Office of Research : Molecular Resource Center
... Molecular Resource Center Equipment Bio-Tek FLX 800TBE Microplate Fluorescence Reader DNA Sequencing and Fragment Analysis Fluorescence Microscopy Illumina Microarray BeadStation Universal Probe Library Liquid Handling Robot Microarrays Phosphor-imaging. The reader has an excitation range of 300-650nm and emission range of 340-800nm. The MRC currently has 360nm, 485nm and 508nm excitation filters as well as 460nm, and 528nm emission filters. DNA Sequencing and Fragment Analysis Back to top The MRC currently has an ABI PRISM 310 and two ABI PRISM 3130XL Genetic Analyzers for DNA sequencing and fragment analysis. Illumina Microarray BeadStation Back to top The MRC in collaboration with the Vision Research Core of the Hamilton Eye Institute is pleased to make available an Illumina whole genome SNP and Microarray gene expression analysis core service at UTHSC.Gene expression analysis includes RNA QA/QC, RNA labeling, processing of chip and data analysis.The ...
http://uthsc.edu/research/molecular_resource/Molecular_Resource_Center_Equipment.php
*  PCR Arrays - Pathway Focused Gene Expression Profiling Using Quantitative RT-PCR
... Research Area Complete Array List Browse by Pathway Apoptosis. Browse by Disease Cancer. PCR Arrays are the most reliable tools for analyzing the expression of a focused panel of genes. Each 96-well plate, 384-well plate, or 100-well disc PCR Array includes SYBR Green-optimized primer assays for a thoroughly researched panel of relevant, pathway- or disease-focused genes. New developments in PCR Array technology enable optimal performance of RT Profiler PCR Arrays using RNA prepared from regular samples 0.1 - 5 ug RNA , FFPE samples, and small samples 1 - 100 ng RNA. See the PCR Array Protocol Guide to learn more. Why PCR Arrays. Pathway Focused: Profile the expression of a panel of genes relevant to a pathway or disease state. Simple and Accurate: Simple real-time PCR method provides high sensitivity and wider dynamic range. Specificity: The specificity of the system, imparted by the combination of SYBR Green primers and PCR master mixes, guarantees a single product of the predicted size from every ...
http://sabiosciences.com/PCRArrayPlate.php
*  TaqMan® Probe-Based Gene Expression Analysis
... by Life Technologies. Applications Technologies. All Categories Search. Contact Information. TaqMan Assays. DNA / RNA Purification. Gene Expression. PCR. Real-Time PCR. siRNA, miRNA Non-Coding RNA. Custom TaqMan Array. TaqMan Gene Expression Assays. TaqMan MicroRNA Assays. TaqMan SNP Genotyping Assays. TaqMan Protein Assays. Applications Technologies. Home > Applications & Technologies > qPCR Real-Time PCR > TaqMan® Probe-Based Gene Expression Analysis. TaqMan® Probe-Based Gene Expression Analysis. RNA from samples of interest is reverse transcribed into cDNA, and the synthesized cDNA serves as the template for real-time PCR. Which TaqMan Gene Expression Assay or Array is right for you. 96-Well Plates Easy-to-use 96-well plates are compatible with our 7500 Fast, 7900HT, ViiA 7 and StepOnePlus Real-Time PCR Systems. 384-Well Plates 384-well plates can be configured with any TaqMan Gene Expression Assays, including custom assays designed to your target sequences. 384-Well Microfluidic Cards ...
http://appliedbiosystems.com/absite/us/en/home/applications-technologies/real-time-pcr/taqman-probe-based-gene-expression-analysis.html
*  T Ideker
Research Topics galactose fungal gene expression regulation galactosephosphates human genome project fungal rna fungal genome monosaccharide transport proteins yeasts oligonucleotide array sequence analysis genetic databases likelihood functions gene expression profiling proteome fungal proteins factual databases computational biology saccharomyces cerevisiae proteins culture media saccharomyces cerevisiae genetic models computer assisted image processing expressed sequence tags complementary dna molecular probe techniques prostate. Publications Integrated genomic and proteomic analyses of a systematically perturbed metabolic network T Ideker The Institute for Systems Biology, 4225 Roosevelt Way NE, Suite 200, Seattle, WA 98105, USA Science 292:929-34. 2001 Testing for differentially-expressed genes by maximum-likelihood analysis of microarray data T Ideker Department of Molecular Biotechnology, University of Washington, Seattle, WA 98195, USA J Comput Biol 7:805-17. 2001 Negative selection: a ...
http://labome.org/expert/usa/institute/ideker/t-ideker-622821.html
*  GEO Profile Links for PubMed (Select 15961561) - GEO Profiles - NCBI
GEO Profile Links for PubMed Select 15961561 - GEO Profiles - NCBI. NCBI. BLAST Basic Local Alignment Search Tool. BLAST Basic Local Alignment Search Tool. DataSet type: Expression profiling by array, transformed count, 12 samples ID: 106850905 GEO DataSets Gene UniGene Profile neighbors Chromosome neighbors. DataSet type: Expression profiling by array, transformed count, 12 samples ID: 106850904 GEO DataSets Gene UniGene Profile neighbors Chromosome neighbors. DataSet type: Expression profiling by array, transformed count, 16 samples ID: 92080805 GEO DataSets Gene UniGene Profile neighbors Chromosome neighbors. DataSet type: Expression profiling by array, transformed count, 16 samples ID: 92080804 GEO DataSets Gene UniGene Profile neighbors Chromosome neighbors. DataSet type: Expression profiling by array, count, 40 samples ID: 91918105 GEO DataSets Gene UniGene Profile neighbors Chromosome neighbors. DataSet type: Expression profiling by array, count, 40 samples ID: 91918104 GEO DataSets Gene UniGene ...
http://ncbi.nlm.nih.gov/geoprofiles?LinkName=pubmed_geoprofiles&from_uid=15961561
*  Gene Ontology Classifications
Genes. Genes. Genes Markers Query. Batch Query. Mouse Genome Browser. Human Disease OMIM Browser. Gene Expression Data Query. Gene Expression Literature Query. GO Browser. Genes Markers Query. Batch Query. Mouse Genome Browser. Batch Query. Gene Expression Literature Query. GO Browser. Human Disease OMIM Browser. Batch Query. Mouse Genome Browser. Batch Query. Genes Markers. Sequence Data. Gene Ontology Data. Gene Expression. Nucleic Acids Research Journal Database Summary. Tabular View GO Graph GO curators for mouse genes have assigned the following annotations to the gene product of Stx16. Summary from NCBI RefSeq This gene encodes a protein that is a member of the syntaxin or t-SNARE target-SNAP receptor family. These proteins are found on cell membranes and serve as the targets for V-SNARES vesicle-SNAP receptors permitting specific synaptic vesicle docking and fusion. Summary text based on GO annotations supported by experimental evidence in mouse Researchers have inferred from direct assay, that the ...
http://informatics.jax.org/go/marker/MGI:1923396
*  Gene Ontology Classifications
Genes. Expression. Genes. Genes Markers Query. Batch Query. Mouse Genome Browser. Human Disease OMIM Browser. Expression. Gene Expression Data Query. Gene Expression Literature Query. GO Browser. Genes Markers Query. Batch Query. Mouse Genome Browser. Batch Query. Gene Expression Literature Query. GO Browser. Human Disease OMIM Browser. Mouse Developmental Anatomy Browser. Batch Query. Mouse Genome Browser. Batch Query. Genes Markers. Sequence Data. Gene Ontology Data. Gene Expression. Nucleic Acids Research Journal Database Summary. Symbol Name ID Kcns2 K+ voltage-gated channel, subfamily S, 2 MGI:1197011. Tabular View GO Graph GO curators for mouse genes have assigned the following annotations to the gene product of Kcns2. Summary text based on GO annotations supported by experimental evidence in other organisms From comparative sequence analysis see table for details, MGI curators have determined that the gene product of Kcns2 : participates in the following biological processes: potassium ion ...
http://informatics.jax.org/go/marker/MGI:1197011
*  Gene Ontology Classifications
Genes Markers Query. Batch Query. Mouse Genome Browser. Gene Expression Data Query. Genes Markers Query. Batch Query. Mouse Genome Browser. Batch Query. Batch Query. Mouse Genome Browser. Batch Query. Genes Markers. Sequence Data. Gene Ontology Data. Phenotypes Mutants Community Resources. Symbol Name ID Cacna2d2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 MGI:1929813. Tabular View GO Graph GO curators for mouse genes have assigned the following annotations to the gene product of Cacna2d2. This gene encodes the alpha-2/delta subunit of the voltage-dependent calcium channel complex. Summary text based on GO annotations supported by experimental evidence in mouse Researchers have inferred from direct assay, that the gene product of Cacna2d2 performs the following molecular functions: voltage-gated calcium channel activity. is located in the following cellular components: voltage-gated calcium channel complex. Researchers have inferred, based on phenotypic analysis of mouse mutants, that ...
http://informatics.jax.org/go/marker/MGI:1929813
*  DNA Microarrays for KGD1 and YIL127C
If a non-annotated gene's are expression pattern is similar to an annotated gene, then may share a common function, promoter or transcription factor. Figure 1: TCA cycle for yeast. MICROARRAY DATA FOR KGD1 Eleven different experiments are listed in the Expression Connection database: Expression response to different alpha factor concentrations 1 Expression response to alpha factor 2 Expression response to DNA damaging agents 3 Expression response to diauxic shift 4 Expression response to glucose limitation 5 Expression regulated by PHO pathway 6 Expression response to environmental changes 7 Expression response during the cell cycle 8 Expression response to histone depletion 9 Expression response to sporulation 10 Expression response to varying zinc levels 11. Figure 5: Scale for gene induction and repression for all DNA microarray experiments. Figure 6: Gene expression for KGD1 at various alpha factor concentrations. This suggests that enzymes in a metabolic pathway have similar expression profiles. Figure ...
http://bio.davidson.edu/courses/genomics/2002/Cubre/project3.html
*  Patent US7026121 - Methods and compositions for diagnosing and monitoring transplant rejection - Goo
While blood provides a very attractive substrate for the study of diseases using expression profiling techniques, and for the development of diagnostic technologies and the identification of therapeutic targets, the value of expression profiling in blood samples rests on the degree to which changes in gene expression in these cell types are associated with a predisposition to, and pathogenesis and progression of a disease. A Example of rejection and no-rejection samples expression data for 5 marker genes. This table contains 4517 identified cDNAs and cDNA regions of genes that are members of a leukocyte candidate library, for use in measuring the expression of nucleotide sequences that could subsequently be correlated with human clinical conditions. For each of the CMV gene expression markers identified in Table 11A, 2 sets of PCR primer pairs are shown that were derived by the methods described in example 25. For each of the rejection gene expression markers identified in Table 12A, 2 sets of PCR primer ...
http://google.com/patents/US7026121?dq=6,712,702
*  Gene Ontology Classifications
Genes. Genes. Genes Markers Query. Batch Query. Mouse Genome Browser. Gene Expression Data Query. Genes Markers Query. Batch Query. Mouse Genome Browser. Batch Query. Batch Query. Mouse Genome Browser. Batch Query. Genes Markers. Sequence Data. Gene Ontology Data. Gene Expression. Mouse Resources & Model Organism Links. Tabular View GO Graph GO curators for mouse genes have assigned the following annotations to the gene product of Sh2d1a. Summary text based on GO annotations supported by experimental evidence in mouse The gene product of Sh2d1a has been shown to bind to the gene products of Slamf1. Researchers have inferred, based on phenotypic analysis of mouse mutants, that the gene product of Sh2d1a participates in the following biological processes: humoral immune response. Researchers have inferred, based on genetic interactions, that the gene product of Sh2d1a participates in the following biological processes: positive regulation of natural killer cell mediated cytotoxicity based on ...
http://informatics.jax.org/go/marker/MGI:1328352
*  Gene Ontology Classifications
Genes. Genes. Genes Markers Query. Batch Query. Mouse Genome Browser. Gene Expression Data Query. Genes Markers Query. Batch Query. Mouse Genome Browser. Batch Query. Batch Query. Mouse Genome Browser. Batch Query. Genes Markers. Sequence Data. Gene Ontology Data. Tabular View GO Graph GO curators for mouse genes have assigned the following annotations to the gene product of Trf. Summary text based on GO annotations supported by experimental evidence in mouse Researchers have inferred from direct assay, that the gene product of Trf participates in the following biological processes: actin filament organization. Researchers have inferred, based on phenotypic analysis of mouse mutants, that the gene product of Trf participates in the following biological processes: iron ion transport. Summary text based on GO annotations supported by experimental evidence in other organisms From comparative sequence analysis see table for details, MGI curators have determined that the gene product of Trf : ...
http://informatics.jax.org/go/marker/MGI:98821
*  Gene Ontology Classifications
Genes Markers Query. Mouse Genome Browser. Gene Expression Data Query. Genes Markers Query. Mouse Genome Browser. Mouse Genome Browser. Genes Markers. Sequence Data. Gene Ontology Data. Summary text based on GO annotations supported by experimental evidence in mouse Researchers have inferred from direct assay, that the gene product of Stxbp1 participates in the following biological processes: negative regulation of synaptic transmission, GABAergic. Researchers have inferred, based on physical interactions, that the gene product of Stxbp1 performs the following molecular functions: syntaxin-1 binding. Researchers have inferred, based on phenotypic analysis of mouse mutants, that the gene product of Stxbp1 participates in the following biological processes: axon target recognition. Summary text based on GO annotations supported by experimental evidence in other organisms From comparative sequence analysis see table for details, MGI curators have determined that the gene product of Stxbp1 : ...
http://informatics.jax.org/go/marker/MGI:107363
*  Smokers undergo the same changes in gene expression as patients with COPD
... Home. Diseases, Conditions, Syndromes. May 9, 2011 Smokers undergo the same changes in gene expression as patients with COPD May 9, 2011. Smokers undergo the same changes in gene expression as patients with COPD. Credit: SINC 'Healthy' smokers experience changes in the gene expression of their lungs similar to that suffered by smokers who have developed Chronic Obstructive Pulmonary Disease COPD. This is the conclusion of a new study, led by Catalan researchers, which confirms the crucial role that smoking plays in causing these alterations. "Our objective was to analyse the expression of a range of genes in the pulmonary tissue samples of patients with COPD, whether smokers or not, and people who had undergone operations for cancer or lung transplants", Ricardo Bastos, lead author of the study and a researcher at the August Pi i Sunyer Biomedical Research Institute IDIBAPS, tells SINC. Using the real-time polymerase chain reaction PCR technique, the scientists analysed the expression of 42 genes ...
http://medicalxpress.com/news/2011-05-smokers-gene-patients-copd.html
*  Digital Gene-Expression Profiling | GEN Magazine Articles | GEN
Transitioning from Traditional Assay Formats to HTRF Technology. Transitioning from Traditional Assay Formats to HTRF Technology. Market & Tech Analysis. Page 3 of 5 Single Molecule Sequencing Patrice Milos, Ph.D., vp and CSO at Helicos Biosciences, described the company s genetic analysis system at Cambridge Healthtech s Next Generation Sequencing conference in San Diego last month in a presentation entitled, Enabling True Biology with Helicos Single Molecule Sequencing. DNA sample preparation on the HeliScope Single Molecule Sequencer requires no ligation steps or PCR amplification, Dr. The basic process for quantitative RNA analysis involves creating a single-stranded copy of the total or poly A+ RNA sample using reverse transcriptase, adding a polyA tail to the cDNA, and allowing these to hybridize to a flow cell surface containing oligo dT to initiate sequencing by synthesis reactions of the single-copy transcript tags. The 50-channel HeliScope can generate 12 to 14 million reads in ...
http://genengnews.com/gen-articles/digital-gene-expression-profiling/2844/?page=3
*  Basal Cell Carcinoma, Multiple disease: Malacards - Research Articles, Symptoms, Drugs, Genes, C
Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications ...
http://malacards.org/card/basal_cell_carcinoma_multiple
*  Fgfr2-Related Craniosynostosis disease: Malacards - Research Articles, Symptoms, Drugs, Genes, C
Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications ...
http://malacards.org/card/fgfr2_related_craniosynostosis
*  Orbit Rhabdomyosarcoma disease: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical
Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications ...
http://malacards.org/card/orbit_rhabdomyosarcoma
*  Branchiootorenal Spectrum Disorders disease: Malacards - Research Articles, Symptoms, Drugs, Gen
Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications ...
http://malacards.org/card/branchiootorenal_spectrum_disorders
*  Swine Influenza disease: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical Trials
Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications ...
http://malacards.org/card/swine_influenza
*  Deafness, Autosomal Dominant 3b disease: Malacards - Research Articles, Symptoms, Drugs, Genes,
Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications ...
http://malacards.org/card/deafness_autosomal_dominant_3b
*  Umod-Associated Kidney Disease: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical
Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications ...
http://malacards.org/card/umod_associated_kidney_disease
*  Large-Related Muscle Diseases: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical T
Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications ...
http://malacards.org/card/large_related_muscle_diseases
*  Venous Tributary Occlusion of Retina disease: Malacards - Research Articles, Symptoms, Drugs, Ge
Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications ...
http://malacards.org/card/venous_tributary_occlusion_of_retina
*  Dfna 8/12 Nonsyndromic Hearing Loss and Deafness disease: Malacards - Research Articles, Symptom
Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications ...
http://malacards.org/card/dfna_8_12_nonsyndromic_hearing_loss_and_deafness
*  Brachyolmia disease: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical Trials
Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications ...
http://malacards.org/card/brachyolmia
*  Scotoma disease: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical Trials
Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications ...
http://malacards.org/card/scotoma
*  Non-Classic Cystic Fibrosis-Like Syndrome disease: Malacards - Research Articles, Symptoms, Drug
Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications ...
http://malacards.org/card/non_classic_cystic_fibrosis_like_syndrome
*  Myopathy, Distal, Tateyama Type disease: Malacards - Research Articles, Symptoms, Drugs, Genes,
Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications ...
http://malacards.org/card/myopathy_distal_tateyama_type
*  Splenic Sequestration disease: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical T
Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications ...
http://malacards.org/card/splenic_sequestration
*  Progeroid Laminopathies disease: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical
Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications Anatomical Context Animal Models Compounds Drugs & Therapeutics Expression Genes Genetic Tests GO Terms Pathways Products Publications Related Diseases Sources Summaries Symptoms Variations Top Bottom. Jump to section Aliases & Classifications ...
http://malacards.org/card/progeroid_laminopathies
*  Differential gene expression triggered by highly cytotoxic α-Emitter-immunoconjugates in gastric ca
... ncer cells - Springer. Affiliated with Department of Nuclear Medicine, Technische Universität München. Affiliated with Department of Nuclear Medicine, Technische Universität München. Affiliated with Department of Nuclear Medicine, Technische Universität München. Share Share this content on Facebook Share this content on Twitter Share this content on LinkedIn. CrossRef. PubMed. CrossRef. PubMed. PubMed. CrossRef. CrossRef. PubMed. Cancer Res 66:8227–8232 doi: 10.​1158/​0008-5472.​CAN-06-1189. CrossRef. PubMed. PubMed. Huber R, Seidl C, Schmid E, Seidenschwang S, Becker KF, Schuhmacher C, Apostolidis C, Nikula T, Kremmer E, Schwaiger M, Senekowitsch-Schmidtke R 2003 Locoregional α-radioimmunotherapy of intraperitoneal tumor cell dissemination using a tumor specific monoclonal antibody. Seidl C, Schröck H, Seidenschwang S, Beck R, Schmid E, Abend M, Becker KF, Apostolidis C, Nikula TK, Kremmer E, Schwaiger M, Senekowitsch-Schmidtke R 2005 Cell death triggered by alpha-emitting 213 Bi-immunoconjugates in ...
http://link.springer.com/article/10.1007/s10637-008-9214-4
*  Gene Expression - DnaTube.com - Scientific Video and Animation Site
... DNATUBE. . Sign In. Sign In. Sign In. Remember me. Forgot password. Connect With Facebook. Manual create account. Videos. Lectures. Upload. share on twitter. share this page with the world. 12900 views. Gene Expression Gene Expression which information from a gene is used in the synthesis of a functional gene product is shown in this video. more... Gene Expression which information from a gene is used in the synthesis of a functional gene product is shown in this video. less... Comments. Embed. Download. Features. You need to login to download this video. or login or signup. Channels:. Genetics Tags:. geneexpression Upload by:. shiva on 03-10-2007. Duration: 6m 8s. Watch VIDEO. 28263 views. Mechanism of gene expression 02:02. Watch VIDEO. 1811 views. Microarray Gene expression 01:22. Watch VIDEO. 2001 views. Lec 18 - Biology 1A -Gene Expression I - ... Watch VIDEO. 1873 views. Lec 19 - Biology 1A - Gene Expression II ... 53:21. Watch VIDEO. 1902 views. Lec 20 - Biology 1A - Regulation of Gene ... 55:06. ...
http://dnatube.com/video/1064/Gene-Expression

ParaHox: The ParaHox gene cluster is an array of homeobox genes (involved in morphogenesis, the regulation of patterns of anatomical development) from the Gsx, Xlox (Pdx) and Cdx gene families.Gene signature: A gene signature is a group of genes in a cell whose combined expression patternItadani H, Mizuarai S, Kotani H. Can systems biology understand pathway activation?Cellular microarray: A cellular microarray is a laboratory tool that allows for the multiplex interrogation of living cells on the surface of a solid support. The support, sometimes called a "chip", is spotted with varying materials, such as antibodies, proteins, or lipids, which can interact with the cells, leading to their capture on specific spots.Branching order of bacterial phyla (Gupta, 2001): There are several models of the Branching order of bacterial phyla, one of these was proposed in 2001 by Gupta based on conserved indels or protein, termed "protein signatures", an alternative approach to molecular phylogeny. Some problematic exceptions and conflicts are present to these conserved indels, however, they are in agreement with several groupings of classes and phyla.RV coefficient: In statistics, the RV coefficientColes PhillipsRAPD: RAPD (pronounced "rapid") stands for 'Random Amplified Polymorphic DNA'. It is a type of PCR reaction, but the segments of DNA that are amplified are random.Modified Maddrey's discriminant function: The modified Maddrey's discriminant function) was originally described by Maddrey and Boitnott to predict prognosis in alcoholic hepatitis. It is calculated by a simple formula:Genetic variation: right|thumbGeographical cluster: A geographical cluster is a localised anomaly, usually an excess of something given the distribution or variation of something else. Often it is considered as an incidence rate that is unusual in that there is more of some variable than might be expected.DNA sequencer: A DNA sequencer is a scientific instrument used to automate the DNA sequencing process. Given a sample of DNA, a DNA sequencer is used to determine the order of the four bases: G (guanine), C (cytosine), A (adenine) and T (thymine).Clonal Selection Algorithm: In artificial immune systems, Clonal selection algorithms are a class of algorithms inspired by the clonal selection theory of acquired immunity that explains how B and T lymphocytes improve their response to antigens over time called affinity maturation. These algorithms focus on the Darwinian attributes of the theory where selection is inspired by the affinity of antigen-antibody interactions, reproduction is inspired by cell division, and variation is inspired by somatic hypermutation.Flushing (physiology)Phenotype microarray: The phenotype microarray approach is a technology for high-throughput phenotyping of cells.Symmetry element: A symmetry element is a point of reference about which symmetry operations can take place. In particular, symmetry elements can be centers of inversion, axes of rotation and mirror planes.Iron-sulfur cluster biosynthesis protein family: In molecular biology, the iron-sulfur cluster biosynthesis protein family of includes proteins involved in biogenesis of Fe-S clusters (iron-sulfur cluster insertion protein, Fe/S biogenesis protein). This family includes IscA, HesB, YadR and YfhF-like proteins.Generalizability theory: Generalizability theory, or G Theory, is a statistical framework for conceptualizing, investigating, and designing reliable observations. It is used to determine the reliability (i.Protein primary structure: The primary structure of a peptide or protein is the linear sequence of its amino acid structural units, and partly comprises its overall biomolecular structure. By convention, the primary structure of a protein is reported starting from the amino-terminal (N) end to the carboxyl-terminal (C) end.Health geography: Health geography is the application of geographical information, perspectives, and methods to the study of health, disease, and health care.Thermal cyclerMac OS X Server 1.0Ferric uptake regulator family: In molecular biology, the ferric uptake regulator (FUR) family of proteins includes metal ion uptake regulator proteins. These are responsible for controlling the intracellular concentration of iron in many bacteria.Amplified fragment length polymorphismPSI Protein Classifier: PSI Protein Classifier is a program generalizing the results of both successive and independent iterations of the PSI-BLAST program. PSI Protein Classifier determines belonging of the found by PSI-BLAST proteins to the known families.CS-BLASTInverse probability weighting: Inverse probability weighting is a statistical technique for calculating statistics standardized to a population different from that in which the data was collected. Study designs with a disparate sampling population and population of target inference (target population) are common in application.Glossary of scientific names: A glossary of the meaning of scientific names of living things, viruses and prions .Microsatellite: A microsatellite is a tract of repetitive DNA in which certain DNA motifs (ranging in length from 2–5 base pairs) are repeated, typically 5-50 times. Microsatellites occur at thousands of locations in the human genome and they are notable for their high mutation rate and high diversity in the population.Temporal analysis of products: Temporal Analysis of Products (TAP), (TAP-2), (TAP-3) is an experimental technique for studyingWormsgrabenPulsenet: PulseNet is a network run by the Centers for Disease Control and Prevention (CDC) which brings together public health and food regulatory agency laboratories around the United States.http://www.Closed-ended question: A closed-ended question is a question format that limits respondents with a list of answer choices from which they must choose to answer the question.Dillman D.Molecular evolution: Molecular evolution is a change in the sequence composition of cellular molecules such as DNA, RNA, and proteins across generations. The field of molecular evolution uses principles of evolutionary biology and population genetics to explain patterns in these changes.Sequence clustering: In bioinformatics, sequence clustering algorithms attempt to group biological sequences that are somehow related. The sequences can be either of genomic, "transcriptomic" (ESTs) or protein origin.Amplified Ribosomal DNA Restriction Analysis: Amplified rDNA (Ribosomal DNA) Restriction Analysis is the extension of the technique of RFLP (restriction fragment length polymorphism) to the gene encoding the small (16s) ribosomal subunit of bacteria. The technique involves an enzymatic amplification using primers directed at the conserved regions at the ends of the 16s gene, followed by digestion using tetracutter Restriction enzymes.Genetic structure: Genetic structure refers to any pattern in the genetic makeup of individuals within a population.Interval boundary element method: Interval boundary element method is classical boundary element method with the interval parameters.
Layout of the Port of Tianjin: The Port of Tianjin is divided into nine areas: the three core (“Tianjin Xingang”) areas of Beijiang, Nanjiang, and Dongjiang around the Xingang fairway; the Haihe area along the river; the Beitang port area around the Beitangkou estuary; the Dagukou port area in the estuary of the Haihe River; and three areas under construction (Hanggu, Gaoshaling, Nangang).University of CampinasGene polymorphismRegularized canonical correlation analysis: Regularized canonical correlation analysis is a way of using ridge regression to solve the singularity problem in the cross-covariance matrices of canonical correlation analysis. By converting \operatorname{cov}(X, X) and \operatorname{cov}(Y, Y) into \operatorname{cov}(X, X) + \lambda I_X and \operatorname{cov}(Y, Y) + \lambda I_Y, it ensures that the above matrices will have reliable inverses.Ligation-independent cloning: Ligation-independent cloning (LIC) is a form of molecular cloning that is able to be performed without the use of restriction endonucleases or DNA ligase. This allows genes that have restriction sites to be cloned without worry of chopping up the insert.Multiple Loci VNTR Analysis: Multiple Loci VNTR Analysis (MLVA ) is a method employed for the genetic analysis of particular microorganisms, such as pathogenic bacteria, that takes advantage of the polymorphism of tandemly repeated DNA sequences. A "VNTR" is a "variable-number tandem repeat".Exogenous bacteria: Exogenous bacteria are microorganisms introduced to closed biological systems from the external world. They exist in aquatic and terrestrial environments, as well as the atmosphere.Hyperparameter: In Bayesian statistics, a hyperparameter is a parameter of a prior distribution; the term is used to distinguish them from parameters of the model for the underlying system under analysis.List of strains of Escherichia coli: Escherichia coli is a well studied bacterium that was first identified by Theodor Escherich, after whom it was later named.Extracellular: In cell biology, molecular biology and related fields, the word extracellular (or sometimes extracellular space) means "outside the cell". This space is usually taken to be outside the plasma membranes, and occupied by fluid.List of geographic information systems software: GIS software encompasses a broad range of applications which involve the use of a combination of digital maps and georeferenced data. GIS software can be sorted into different categories.Reaction coordinateEukaryotic transcription: Eukaryotic transcription is the elaborate process that eukaryotic cells use to copy genetic information stored in DNA into units of RNA replica. Gene transcription occurs in both eukaryotic and prokaryotic cells.Solution precursor plasma spray: Solution Precursor Plasma Spray (SPPS) is a thermal spray process where a feedstock solution is heated and then deposited onto a substrate. Basic properties of the process are fundamentally similar to other plasma spraying processes.Chromosome regionsSilent mutation: Silent mutations are mutations in DNA that do not significantly alter the phenotype of the organism in which they occur. Silent mutations can occur in non-coding regions (outside of genes or within introns), or they may occur within exons.Peptide microarray: A peptide microarray (also commonly known as peptide chip or peptide epitope microarray) is a collection of peptides displayed on a solid surface, usually a glass or plastic chip. Peptide chips are used by scientists in biology, medicine and pharmacology to study binding properties and functionality and kinetics of protein-protein interactions in general.Proteomics Standards Initiative: The Proteomics Standards Initiative (PSI) is a working group of Human Proteome Organization. It aims to define data standards for proteomics in order to facilitate data comparison, exchange and verification.Fruit snack: A fruit snack is a processed food eaten as a snack in the United States. Fruit snacks are very similar to gummi candies.Transfer-messenger RNA: Transfer-messenger RNA (abbreviated tmRNA, also known as 10Sa RNA and by its genetic name SsrA) is a bacterial RNA molecule with dual tRNA-like and messenger RNA-like properties. The tmRNA forms a ribonucleoprotein complex (tmRNP) together with Small Protein B (SmpB), Elongation Factor Tu (EF-Tu), and ribosomal protein S1.Gemmatimonadetes: The Gemmatimonadetes are a family of bacteria, given their own phylum (Gemmatimonadetes). This bacterium makes up about 2% of soil bacterial communities and has been identified as one of the top nine phyla found in soils; yet, there are currently only six cultured isolates.Library (biology): In molecular biology, a library is a collection of DNA fragments that is stored and propagated in a population of micro-organisms through the process of molecular cloning. There are different types of DNA libraries, including cDNA libraries (formed from reverse-transcribed RNA), genomic libraries (formed from genomic DNA) and randomized mutant libraries (formed by de novo gene synthesis where alternative nucleotides or codons are incorporated).Chorda tympani: The chorda tympani is a branch of the facial nerve that originates from the taste buds in the front of the tongue, runs through the middle ear, and carries taste messages to the brain. It joins the facial nerve (cranial nerve VII) inside the facial canal, at the level where the facial nerve exits the skull via the petrotympanic fissure.De novo transcriptome assembly: De novo transcriptome assembly is the method of creating a transcriptome without the aid of a reference genome.Mature messenger RNA: Mature messenger RNA, often abbreviated as mature mRNA is a eukaryotic RNA transcript that has been spliced and processed and is ready for translation in the course of protein synthesis. Unlike the eukaryotic RNA immediately after transcription known as precursor messenger RNA, it consists exclusively of exons, with all introns removed.Matrix model: == Mathematics and physics ==

(1/16506) Ringo, Doty, Demeter and Simard, Cerebral Cortex 1994;4:331-343: a proof of the need for the spatial clustering of interneuronal connections to enhance cortical computation.

It has been argued that an important principle driving the organization of the cerebral cortex towards local processing has been the need to decrease time lost to interneuronal conduction delay. In this paper, I show for a simplified model of the cerebral cortex, using analytical means, that if interneuronal conduction time increases proportional to interneuronal distance, then the only way to increase the numbers of synaptic events occurring in a fixed finite time period is to spatially cluster interneuronal connections.  (+info)

(2/16506) Cluster survey evaluation of coverage and risk factors for failure to be immunized during the 1995 National Immunization Days in Egypt.

BACKGROUND: In 1995, Egypt continued to experience endemic wild poliovirus transmission despite achieving high routine immunization coverage with at least three doses of oral poliovirus vaccine (OPV3) and implementing National Immunization Days (NIDs) annually for several years. METHODS: Parents of 4188 children in 3216 households throughout Egypt were surveyed after the second round of the 1995 NIDs. RESULTS: Nationwide, 74% of children are estimated to have received both NID doses, 17% one NID dose, and 9% neither NID dose. Previously unimmunized (47%) or partially immunized (64%) children were less likely to receive two NID doses of OPV than were fully immunized children (76%) (P < 0.001). Other risk factors nationwide for failure to receive NID OPV included distance from residence to nearest NID site >10 minute walk (P < 0.001), not being informed about the NID at least one day in advance (P < 0.001), and residing in a household which does not watch television (P < 0.001). Based on these findings, subsequent NIDs in Egypt were modified to improve coverage, which has resulted in a marked decrease in the incidence of paralytic poliomyelitis in Egypt. CONCLUSIONS: In selected situations, surveys can provide important information that is useful for planning future NIDs.  (+info)

(3/16506) Clusters of Pneumocystis carinii pneumonia: analysis of person-to-person transmission by genotyping.

Genotyping at the internal transcribed spacer (ITS) regions of the nuclear rRNA operon was performed on isolates of P. carinii sp. f. hominis from three clusters of P. carinii pneumonia among eight patients with haematological malignancies and six with HIV infection. Nine different ITS sequence types of P. carinii sp. f. hominis were identified in the samples from the patients with haematological malignancies, suggesting that this cluster of cases of P. carinii pneumonia was unlikely to have resulted from nosocomial transmission. A common ITS sequence type was observed in two of the patients with haematological malignancies who shared a hospital room, and also in two of the patients with HIV infection who had prolonged close contact on the ward. In contrast, different ITS sequence types were detected in samples from an HIV-infected homosexual couple who shared the same household. These data suggest that person-to-person transmission of P. carinii sp. f. hominis may occur from infected to susceptible immunosuppressed patients with close contact within hospital environments. However direct transmission between patients did not account for the majority of cases within the clusters, suggesting that person-to-person transmission of P. carinii sp. f. hominis infection may be a relatively infrequent event and does not constitute the major route of transmission in man.  (+info)

(4/16506) Influence of sampling on estimates of clustering and recent transmission of Mycobacterium tuberculosis derived from DNA fingerprinting techniques.

The availability of DNA fingerprinting techniques for Mycobacterium tuberculosis has led to attempts to estimate the extent of recent transmission in populations, using the assumption that groups of tuberculosis patients with identical isolates ("clusters") are likely to reflect recently acquired infections. It is never possible to include all cases of tuberculosis in a given population in a study, and the proportion of isolates found to be clustered will depend on the completeness of the sampling. Using stochastic simulation models based on real and hypothetical populations, the authors demonstrate the influence of incomplete sampling on the estimates of clustering obtained. The results show that as the sampling fraction increases, the proportion of isolates identified as clustered also increases and the variance of the estimated proportion clustered decreases. Cluster size is also important: the underestimation of clustering for any given sampling fraction is greater, and the variability in the results obtained is larger, for populations with small clusters than for those with the same number of individuals arranged in large clusters. A considerable amount of caution should be used in interpreting the results of studies on clustering of M. tuberculosis isolates, particularly when sampling fractions are small.  (+info)

(5/16506) Newly recognized focus of La Crosse encephalitis in Tennessee.

La Crosse virus is a mosquito-borne arbovirus that causes encephalitis in children. Only nine cases were reported in Tennessee during the 33-year period from 1964-1996. We investigated a cluster of La Crosse encephalitis cases in eastern Tennessee in 1997. Medical records of all suspected cases of La Crosse virus infection at a pediatric referral hospital were reviewed, and surveillance was enhanced in the region. Previous unreported cases were identified by surveying 20 hospitals in the surrounding 16 counties. Mosquito eggs were collected from five sites. Ten cases of La Crosse encephalitis were serologically confirmed. None of the patients had been discharged from hospitals in the region with diagnosed La Crosse encephalitis in the preceding 5 years. Aedes triseriatus and Aedes albopictus were collected at the case sites; none of the mosquitos had detectable La Crosse virus. This cluster may represent an extension of a recently identified endemic focus of La Crosse virus infection in West Virginia.  (+info)

(6/16506) Hierarchical cluster analysis applied to workers' exposures in fiberglass insulation manufacturing.

The objectives of this study were to explore the application of cluster analysis to the characterization of multiple exposures in industrial hygiene practice and to compare exposure groupings based on the result from cluster analysis with that based on non-measurement-based approaches commonly used in epidemiology. Cluster analysis was performed for 37 workers simultaneously exposed to three agents (endotoxin, phenolic compounds and formaldehyde) in fiberglass insulation manufacturing. Different clustering algorithms, including complete-linkage (or farthest-neighbor), single-linkage (or nearest-neighbor), group-average and model-based clustering approaches, were used to construct the tree structures from which clusters can be formed. Differences were observed between the exposure clusters constructed by these different clustering algorithms. When contrasting the exposure classification based on tree structures with that based on non-measurement-based information, the results indicate that the exposure clusters identified from the tree structures had little in common with the classification results from either the traditional exposure zone or the work group classification approach. In terms of the defining homogeneous exposure groups or from the standpoint of health risk, some toxicological normalization in the components of the exposure vector appears to be required in order to form meaningful exposure groupings from cluster analysis. Finally, it remains important to see if the lack of correspondence between exposure groups based on epidemiological classification and measurement data is a peculiarity of the data or a more general problem in multivariate exposure analysis.  (+info)

(7/16506) A taxonomy of health networks and systems: bringing order out of chaos.

OBJECTIVE: To use existing theory and data for empirical development of a taxonomy that identifies clusters of organizations sharing common strategic/structural features. DATA SOURCES: Data from the 1994 and 1995 American Hospital Association Annual Surveys, which provide extensive data on hospital involvement in hospital-led health networks and systems. STUDY DESIGN: Theories of organization behavior and industrial organization economics were used to identify three strategic/structural dimensions: differentiation, which refers to the number of different products/services along a healthcare continuum; integration, which refers to mechanisms used to achieve unity of effort across organizational components; and centralization, which relates to the extent to which activities take place at centralized versus dispersed locations. These dimensions were applied to three components of the health service/product continuum: hospital services, physician arrangements, and provider-based insurance activities. DATA EXTRACTION METHODS: We identified 295 health systems and 274 health networks across the United States in 1994, and 297 health systems and 306 health networks in 1995 using AHA data. Empirical measures aggregated individual hospital data to the health network and system level. PRINCIPAL FINDINGS: We identified a reliable, internally valid, and stable four-cluster solution for health networks and a five-cluster solution for health systems. We found that differentiation and centralization were particularly important in distinguishing unique clusters of organizations. High differentiation typically occurred with low centralization, which suggests that a broader scope of activity is more difficult to centrally coordinate. Integration was also important, but we found that health networks and systems typically engaged in both ownership-based and contractual-based integration or they were not integrated at all. CONCLUSIONS: Overall, we were able to classify approximately 70 percent of hospital-led health networks and 90 percent of hospital-led health systems into well-defined organizational clusters. Given the widespread perception that organizational change in healthcare has been chaotic, our research suggests that important and meaningful similarities exist across many evolving organizations. The resulting taxonomy provides a new lexicon for researchers, policymakers, and healthcare executives for characterizing key strategic and structural features of evolving organizations. The taxonomy also provides a framework for future inquiry about the relationships between organizational strategy, structure, and performance, and for assessing policy issues, such as Medicare Provider Sponsored Organizations, antitrust, and insurance regulation.  (+info)

(8/16506) Double blind, cluster randomised trial of low dose supplementation with vitamin A or beta carotene on mortality related to pregnancy in Nepal. The NNIPS-2 Study Group.

OBJECTIVE: To assess the impact on mortality related to pregnancy of supplementing women of reproductive age each week with a recommended dietary allowance of vitamin A, either preformed or as beta carotene. DESIGN: Double blind, cluster randomised, placebo controlled field trial. SETTING: Rural southeast central plains of Nepal (Sarlahi district). SUBJECTS: 44 646 married women, of whom 20 119 became pregnant 22 189 times. INTERVENTION: 270 wards randomised to 3 groups of 90 each for women to receive weekly a single oral supplement of placebo, vitamin A (7000 micrograms retinol equivalents) or beta carotene (42 mg, or 7000 micrograms retinol equivalents) for over 31/2 years. MAIN OUTCOME MEASURES: All cause mortality in women during pregnancy up to 12 weeks post partum (pregnancy related mortality) and mortality during pregnancy to 6 weeks postpartum, excluding deaths apparently related to injury (maternal mortality). RESULTS: Mortality related to pregnancy in the placebo, vitamin A, and beta carotene groups was 704, 426, and 361 deaths per 100 000 pregnancies, yielding relative risks (95% confidence intervals) of 0. 60 (0.37 to 0.97) and 0.51 (0.30 to 0.86). This represented reductions of 40% (P<0.04) and 49% (P<0.01) among those who received vitamin A and beta carotene. Combined, vitamin A or beta carotene lowered mortality by 44% (0.56 (0.37 to 0.84), P<0.005) and reduced the maternal mortality ratio from 645 to 385 deaths per 100 000 live births, or by 40% (P<0.02). Differences in cause of death could not be reliably distinguished between supplemented and placebo groups. CONCLUSION: Supplementation of women with either vitamin A or beta carotene at recommended dietary amounts during childbearing years can lower mortality related to pregnancy in rural, undernourished populations of south Asia.  (+info)


algorithm


  • Our k-prototypes algorithm finds minimum distance without distance computations of all attributes between an object and a cluster center, which allows it to reduce time complexity. (mdpi.com)
  • K-means algorithm is one of the simplest clustering algorithm as unsupervised learning, so that is very widely used [ 1 ]. (mdpi.com)
  • A K-means algorithm minimizes the objective function known as squared error function iteratively by finding a new set of cluster centers. (mdpi.com)
  • In a k-means algorithm, the objective function is defined by the sum of square distances between an object and a cluster center. (mdpi.com)
  • Even though the number of clusters is small, the problem of finding an optimal k-means algorithm solution is NP-hard [ 2 , 3 ]. (mdpi.com)
  • K-means algorithm spends a lot of processing time for computing the distances between each of the k cluster centers and the n objects. (mdpi.com)


unsupervised classification


  • Clustering is unsupervised classification: no predefined classes. (ask.com)


computation


  • Computation-at-Risk: Assessing Job Portfolio Management Risk on Clusters. (uni-trier.de)
  • Because objects usually remain in the same clusters after a certain number of iterations, much of the repetitive distance computation is unnecessary. (mdpi.com)


populations


  • To overcome this limitation, we developed Partition-Assisted Clustering and Multiple Alignments of Networks (PAC-MAN) for the fast automatic identification of cell populations in CyTOF data closely matching that of expert manual-discovery, and for alignments between subpopulations across samples to define dataset-level cellular states. (biorxiv.org)
  • These clusters highlight the heterogeneity of employee populations' energy behaviours, demonstrating that assumptions cannot be made about these based on single responses to cross-industry surveys. (surrey.ac.uk)
  • For example, sub-clusters within populations can be identified with both fineSTRUCTURE and fastIBD , and the corresponding clusters can be assessed with supervised ADMIXTURE to detect how they differ from each other. (blogspot.com)


Define


  • First, we further define cluster analysis, illustrating why it is. (ask.com)


Concepts


  • Geographic Information System Landscape Analysis Using GTR 220 Concepts. (ucdavis.edu)


Patterns


  • Comparative Cluster Analysis of Patterns of Vocational Interest. (dtic.mil)
  • The nutritionist approach is to statistically group patterns of consumption using some form of cluster analysis. (bl.uk)


relationship


  • Relationship between clinical clusters and biological factors. (bmj.com)


different


  • Published data on the Strong Vocational Interest Blank profiles of 113 occupational groups are analyzed by three different clustering procedures: Hierarchical grouping of standard scores, Hierarchical grouping of principal axis factor scores, and NORMIX analysis assuming equal covariance matrices for each group. (dtic.mil)
  • Cluster Analysis is a statistical tool for grouping objects belong to one group is more similar to each other rather different from objects belong other. (ask.com)
  • During development, a properly coordinated expression of Hox genes, within their different genomic clusters is critical for patterning the body plans of many animals with a bilateral symmetry. (royalsocietypublishing.org)
  • The biological factors were differentially expressed in subjects stratified by sputum cell counts, asthma control and exacerbation frequency, but were not significantly different across the clinical clusters. (bmj.com)


comparative


  • Thirty two invasive carcinomas and one in situ carcinoma from 16 patients with synchronous, bilateral breast cancer were investigated by means of comparative genomic hybridisation (CGH) and polymerase chain reaction based multiplex microsatellite analysis. (bmj.com)
  • Comparative genomic hybridisation (CGH), as a method to gain an overview of all unbalanced chromosomal alterations within a tumour, in combination with polymerase chain reaction (PCR) based multiplex microsatellite analysis and biomathematical cluster analysis, are an ideal combination of techniques to determine the degree of clonal association between synchronous bilateral breast cancer cases. (bmj.com)


characteristics


  • The household characteristics of the members of the resulting groups are then established by regression analysis. (bl.uk)
  • We performed k-means cluster analysis to determine clinical clusters using the baseline characteristics and sputum differential counts. (bmj.com)


Mapping


  • The U.S Cluster Mapping is a web mapping prototype made for the Institute for Strategy and Competitiveness at the Harvard Business School, to display groups of interconnected companies, universities, and related institutions that arise out of linkages or externalities across industries. (harvard.edu)


data analysis


  • Advances in Data Analysis and Classification (Early Access). (open.ac.uk)
  • Advances in Data Analysis and Classification , 4(4) pp. 223-237. (open.ac.uk)


principal


  • Firstly, a principal components analysis is performed to identify key determinant constructs driving energy-efficient behaviours in organisations, revealing the importance of perceived benefit to the organisation and flexibility of existing performance goals and targets. (surrey.ac.uk)


study


  • This study analyses 35 manufacturing clusters from the Annual Survey of Industrial Firms (ASIFs) Database of China. (harvard.edu)
  • classes and cluster analysis is the study of techniques for automatically finding classes. (ask.com)
  • The study is an attempted synthesis of economic and nutritional analysis. (bl.uk)
  • The coordinated transcription of Hox genes within their respective genomic clusters has been a paradigm to study these questions, ever since high-throughput technologies have been available. (royalsocietypublishing.org)


groups


  • Anti-cluster groups say that billions are still being stockpiled around the world. (bbc.co.uk)
  • As it is a partitioning-based clustering method in cluster analysis, a dataset is partitioned into several groups according to a similarity measure as a distance to the average of a group. (mdpi.com)
  • Secondly, cluster analysis is undertaken, in an effort to identify differences in behavioural influences between demographic groups. (surrey.ac.uk)
  • Cluster analysis to identify groups of drivers and/or events that impact traffic flow. (controleng.com)


identify


  • We identify over a thousand strong clusters, which show economic vitality after the crisis. (harvard.edu)
  • The Cluster Analysis is an explorative analysis that tries to identify structures within the data. (ask.com)
  • The pattern of mediator expression was determined by factor analysis to identify biological factors. (bmj.com)


development


  • Industrial cluster is an important strategy choice for regional economic development and competitiveness. (harvard.edu)
  • Key conditions for the emergence and development of agri-food clusters in Poland. (tind.io)
  • They say their use is already governed by international humanitarian law, and are urging the development of smart cluster munitions that can be better targeted and that do not leave behind many unexploded bombs. (bbc.co.uk)
  • Here, we review some recent observations, which revealed highly dynamic changes in the structure of chromatin at Hox clusters, in parallel with their activation during embryonic development. (royalsocietypublishing.org)
  • The Chandeliers report also consists of development trends, competitive landscape analysis, and key regions development status of Chandeliers market. (beforeitsnews.com)


Collaboration


  • The Harvard Business School's Baker Research Services and Center for Geographic Analysis share a strong cross center collaboration. (harvard.edu)


group


  • in contrast, the two rounds of whole-genome duplications that accompanied the emergence of vertebrates led to the presence of four paralogous Hox clusters in this group, termed HoxA to HoxD , where a total of 39 genes can be scored in mammals (see [ 7 ] for references). (royalsocietypublishing.org)


Performance Analysis


  • Performance Analysis of Repairable Cluster of Workstations. (uni-trier.de)


global


  • Registration gives you instant free access to FlightGlobal's news, in-depth analysis, insight and opinion from our global team of experts, and access to our Flight International and Flight Airline Business online libraries. (naviganti.org)
  • Examples of global agri-food clusters. (tind.io)


population


  • We review recent evidence from the analysis of genome-wide polymorphism data for genetic boundaries delineating human population structure and the main demographic and genomic processes shaping variation, and discuss the implications of population structure for the distribution and discovery of disease-causing genetic variants, in the light of the imminent availability of sequencing data for a multitude of diverse human genomes. (discovermagazine.com)
  • A few months ago I blogged that geneticists have found that they could differentiate population clusters on the scale of nearby villages in Europe! (discovermagazine.com)


Methods


  • Methods of research on industrial cluster change from qualitative to quantitative. (harvard.edu)


growth


  • Aerospace Vehicles and Defense, Automotive and other eight kinds of growing clusters keep high growth and market potential. (harvard.edu)


economic


  • The economic substance of the cluster concept. (tind.io)
  • The economic analysis of diet is based upon the Engel curve. (bl.uk)
  • Therefore this thesis uses Latent Class Cluster Analysis (LCA) to attempt a synthesis of the economic and nutritional approaches. (bl.uk)


structure


  • The fascinating correspondence between the topological organization of Hox clusters and their transcriptional activation in space and time has served as a paradigm for understanding the relationships between genome structure and function. (royalsocietypublishing.org)
  • The Chandeliers Market Latest Research Report provides in-depth analysis of definitions, classifications, applications and Market chain structure. (beforeitsnews.com)


Results


  • The results were analysed conventionally and were also subjected to a biomathematical cluster analysis. (bmj.com)
  • Results We identified four clinical clusters and five biological factors. (bmj.com)


system


  • This course provides you with the knowledge and skills that you need to collect and analyze system performance data from NetApp storage systems that are running clustered Data ONTAP. (hbfites.com)
  • Professionals who manage NetApp storage systems and would like a deeper understanding of Clustered Data ONTAP system performance. (hbfites.com)
  • The instructions in this document assume knowledge of the Solaris TM Operating System and expertise with the volume manager software that is used with Sun Cluster. (oracle.com)


share


  • In many species, they are grouped into genomic clusters, which share a conserved structural organization, indicating that a clustered set of genes was probably present in the ancestor of all extant bilateria. (royalsocietypublishing.org)


usually


  • Cluster bombs usually consist of a large shell containing many small bombs that can cover a wide area. (bbc.co.uk)


Center


  • If data objects have m categorical attributes, the maximum difference of categorical attributes between an object and a cluster center is m. (mdpi.com)
  • If a difference of the minimum distance and the second smallest with numerical attributes is higher than m, we can find the minimum distance between an object and a cluster center without distance computations of categorical attributes. (mdpi.com)
  • The purpose of using k-means is to find clusters that minimize the sum of square distances between each cluster center and all objects in each cluster. (mdpi.com)


services


  • This document contains information about commands that are specific to installing and configuring Sun Cluster data services. (oracle.com)


objects


  • Grouping a set of data objects into clusters. (ask.com)


distribution


  • Identification and spatial distribution of agri-food clusters. (tind.io)
  • The distribution of the five biological factors for each cluster is shown as the mean (SEM) factor scores. (bmj.com)


TECHNIQUES


  • The analysis of mtDNA lineages, passed from mother to daughter, had matured, and techniques for typing the Y chromosome had started to catch up, so that a symmetry between the sexes could arise. (discovermagazine.com)


Table


  • Information about related Sun Cluster topics is available in the documentation that is listed in the following table. (oracle.com)


Impact


  • The Performance Impact of Computational Efficiency on HPC Clusters with Hyper-Threading Technology. (uni-trier.de)


market


  • A complete analysis of the competitive landscape of the Chandeliers market is provided in the report. (beforeitsnews.com)


regional


  • Her research focuses on industrial cluster, regional economics, and urban planning. (harvard.edu)


tool


  • The BBC's defence correspondent Rob Watson says given they are a very effective military tool a ban on cluster bombs is unlikely. (bbc.co.uk)


landscape


  • 2012. Using GRASS and R for landscape regionalization through PAM cluster analysis . (ucdavis.edu)


areas


  • Findings show that manufacturing clusters play an important role in the Chinese economy, and mainly concentrate in eastern coastal areas. (harvard.edu)


countries


  • Norway says it wants the weapons to be outlawed by 2008, but some countries, such as Britain and the US say cluster bombs have a legitimate place on the battlefield. (bbc.co.uk)


approach


  • Sparsest factor analysis for clustering variables: a matrix decomposition approach. (open.ac.uk)
  • A general approach to handling missing values in Procrustes analysis. (open.ac.uk)


sample


  • The sample was obtained through two stage cluster sampling. (bmj.com)


What is the nutritional analysis for 15% drained ground beef?


  • What is the nutritional analysis for 15% drained ground beef? I've had this sort of problem before (though rarely); that is, finding basic info on something as ubiquitous as drained ground beef. But go ahead and google for nutritional analysis "drained ground beef". 9 entries! It's insane! So does anyone know what it is?
  • The USDA does wonderful things and this is no exception: http://www.fns.usda.gov/fdd/facts/schfacts/intro-schoolfacts.htm


Any ways to help relieve some of the pain caused by cluster headaches?


  • If been getting cluster headaches off and on since I was a child, they've been especially bad lately. Any suggestions to help make them a little less intense?
  • Yeah, I don't think that praying will help headaches.... I get migraines not cluster headaches and I understand that they're totally different so nothing I do would probably help you. I don't know if this actually works but supposedly icing the area of pain, oxygen (through deep breathing techniques) and massaging your temples reduces the pain of clusters. Also avoiding alcohol. I'm starting to feel like getting chased from something that I enjoy because of some miserable, jealous, psycho douche bag is bullsh*t.


what is the difference between cluster headaches and migraines?


  • Are they the same? If a Deep brain stimulation would work fo cluster headaches would it work fo migraines?
  • Cluster headaches are typically deep in the eye socket. Migraines are all over. chiropractic care can easily help both almost all the time. Cluster headaches are especially easy to help with normal chiropractic care.


Can you get a cluster of vaginal cysts inside the vagina?


  • Can you get a cluster of vaginal cysts inside the vagina wall just past the opening? They aren't painful like herpes. It feels a little tender but how could it not with cysts on such a tender part of the body.
  • Yes, you can get a cluster of cysts on your labia,they need to be checked out by your doctor though..................


How long does it take to get results from a semen analysis?


  • My husband had to do a semen analysis and I was wondering if anyone knows how long it takes to get the results back. He did it two days ago.
  • He should be able to call and get the results now. They have to do the analysis almost immediately while the sperm are still alive and "fresh". Some places only call if the results are abnormal, some wait until the two of you come in together on your next visit. But they should have the results by now and he should be able to call and get them today.


What is the best way to deal with cluster headaches?


  • I have been getting them for years, but I recently connected the symptoms, frequency, and duration to possibly being cluster headaches. I will see a doctor on Monday, but I would LOVE any suggestions. I have already tried the dark room, cold/hot rags, etc.
  • If your headaches are extreme migraine severity but unilateral (on one side) then they likely are cluster headaches. These are generally characterized with the earmark symptoms of a drilling or throbbing pressure behind one eye or ear, tearing eye, sensitivity to light/sound etc, blurred vision, nausea and/or sweating from extreme pain, a drooping eyelid on the affeted side, and even a bloodshot eye.(I personally always get a bloodshot rearing eye on the affected side). Firstly, You should rule out all other possibilities with an MRI scan. If that comes back okay, you can discuss options with your neuro. For management long-term. here are some suggestions that have worked for me. Make sure your posture isn't hunched over and your neck isn't strained, that's a big one that's often overlooked and understated. Also make sure you aren't grinding your teeth, or that your jaw has too much tension. This may sound cliche, but I found my cluster headaches were due to TMJ, which was caused by a spinal scoliosis, but my own hypertension and stress while sitting caused the scoliosis over time, and also neck and jaw tension, which subsequently triggers cluster headaches. For ongoing symptoms, you need to find what works best for you.. Usually powerful pain medication is the last resort option for people for obvious reasons as they want to avoid addiction. Many chronic migraine sufferers find relief with oxygen therapy, eg:small tanks or cannisters with oxygen masks. I've seen forums where many extol the virtues of oxygen therapy use. I personally use Excedrin Migraine, guided meditation, or (believe it or not) a bite of a Habanero chili pepper. The heat from the Habanero bite stimulates an endorphin rush which often aborts my cluster headache. The tradeoff is a really hot mouth for about two minutes until it naturally wears off. The capsaicin level needs to be significant though (a few drops of specialty extreme hotsauces work as well *eg: Blair's or Dave's) I've also found that controlled deep breathing, relaxing, and neck and shoulder massage can work just as effectively. The idea is that once people have their headaches the inclination is to stress further which often exacerbates the headache and prolongs it. Sometimes for me, just finding a peaceful place to sit alone, "letting go", finding a "Zen" place, relaxing my breathing, and visualizing my blood vessels and nerves going from a dilated state to smooth and normal, while massaging the back of my neck is all I need. The imagery can be icy waves washing over a hot coal until it turns blue and dissipates. It just depends. The key is too find the ability to relax though, after years of suffering cluster headaches I've learned that stressing the state you're in makes it worse, while "letting go" and finding peace can normalize blood vessel tone. The key is to be able to do it In the throws of a cluster headache and all of its crippling pain. If you cannot manage that method, you should try alternative aborting methods such as huffing pure oxygen, a bite of a Habanero, or Excedrin Migraine tablets, Cluster headaches are said to be in the same family as migraines in that they originate from the same place but manifest themselves slightly differently. Whether it's oxygen therapy, Excedrin Migraine, Habanero Chili Peppers, Guided Meditation, or all of the above, I'm fairly certain one or all of the things I've mentioned would work for your cluster headache.. Good Luck.


How can i get blood drawn for a nutritional analysis without a doctor's order?


  • I am currently seeing a nutritionist , who wants me to get a nutritional analysis done. I have the kit with vials and instructions to send in the test. I am having a difficult time finding a nurse and/or phlebotionist to draw the blood without a doctors order. In the state of Illinois a nutritionist is not considered a doctor. Is there an online doctor that can order my blood drawn? Any information will be greatly appreciated. Thank You!!!
  • You can't by law. If you come across a facility that actually draws blood with a needle without being properly certified or under a medical physician then you better run the other direction. They do, do blood stains but those are generally done by finger pricks and sometimes the patient or client does that themselves. Naturopathic physicians or counselors or Nutritionists can lead you in that direction. For starters don't over analyze what you are missing. Try detoxing by eliminating all inappropriate foods. Then start out right by eating fruits and veggies and then low fat proteins such as fat and chicken. It's common sense. Then follow with a multivitamin. People can try every technique possible to short cut for a healthy body, but it will always come down to proper eating.


What's this cookie called?It is a cluster of peanuts,pretzel sticks,held together by pistachio sugar glaze. ?


  • All the ingredients are mixed together and then spooned onto a piece of wax paper. The glaze then hardens a bit to hold the cluster together. Where is a good place to find this recipe, or a similar one?
  • I dunno, but sounds delish!