Chromogenic Compounds
Molecular Structure
Sulfur Compounds
Encyclopedias as Topic
Printing
Color
Congo Red
Photography
Silver
Selective delivery of herpes virus vectors to experimental brain tumors using RMP-7. (1/413)
RMP-7, a bradykinin analog, has been shown to selectively open the blood-tumor barrier for the delivery of chemotherapeutic drugs to brain tumors. In contrast to bradykinin, RMP-7 has no hypotensive effects and has been approved for human use. This study was initiated to determine whether RMP-7 would open the blood-tumor barrier to virus vectors encoding tumor-killing genes in an experimental model. The herpes virus vector used, hrR3, which encodes virus thymidine kinase gene and the lacZ reporter gene, is defective in a gene encoding ribonucleotide reductase, replicates selectively in dividing tumor cells and not in postmitotic neural cells. It was determined that an optimum dose of RMP-7 (1.5-3.0 microg/kg over 10-15 minutes) enhanced viral delivery to brain tumors in rats bearing intracranial 9 L gliosarcomas when infused through the carotid artery immediately prior to virus vector application. Maximum expression of the lacZ reporter gene occurred at 3 days after intracarotid infusion. By 8 days, transgene expression was largely confined to tumor foci away from the main tumor mass. Viral delivery was essentially specific to tumor cells, with little transgene expression elsewhere in the brain. Minimal uptake and pathology was noted in the kidney, spleen, and liver. These findings indicate that intracarotid delivery of RMP-7 can augment the selective delivery of virus vectors to brain tumors in an experimental rat model, with the potential for application to human brain tumors. (+info)Thermal effects on an enzymatically latent conformation of coagulation factor VIIa. (2/413)
Activation of the zymogen factor VII yields an enzyme form, factor VIIa, with only modest activity. The thermal effect on this low activity of factor VIIa and its enhancement by the cofactor tissue factor was investigated. Factor VIIa activity measured with a chromogenic peptide substrate is characterized by an unusual temperature dependency which indicates that the activated protease exists in an equilibrium between a latent (enzymatically inactive) and an active conformation. As shown by calorimetry and activity measurements the thermal effects on factor VIIa are fully reversible below the denaturation temperature of 58.1 degrees C. A model for factor VIIa has been proposed [Higashi, S., Nishimura, H., Aita, K. & Iwanaga, S. (1994) J. Biol. Chem. 269, 18891-18898] in which the protease is supposed to exist primarily as a latent enzyme form because of the poor incorporation into the protease structure of the N-terminal Ile153 released by proteolytic cleavage during activation of factor VII. Binding of tissue factor to factor VIIa is assumed to shift the equilibrium towards an active conformation in which the N-terminal Ile153 forms a salt bridge with Asp343. We corroborate the validity of this model by: (a) chemical modification of factor VIIa; this suggests that the thermal effect on the equilibrium between the active and inactive conformation is reflected in the relative accessibility of the active site and the N-terminal Ile153; (b) measurements of factor VIIa binding to tissue factor indicating that complex formation is favoured by stabilization of the active conformation; and (c) activity measurements of a cross-linked factor VIIa-tissue factor complex; this showed that cross-linking stabilized the active conformation of factor VIIa and essentially prevented its thermally-induced transformation into the inactive state. (+info)Amino acid sequence of trocarin, a prothrombin activator from Tropidechis carinatus venom: its structural similarity to coagulation factor Xa. (3/413)
Among snake venom procoagulant proteins, group II prothrombin activators are functionally similar to blood coagulation factor Xa. We have purified and partially characterized the enzymatic properties of trocarin, the group II prothrombin activator from the venom of the Australian elapid, Tropidechis carinatus (rough-scaled snake). Prothrombin activation by trocarin is enhanced by Ca2+, phospholipids, and factor Va, similar to that by factor Xa. However, its amidolytic activity on peptide substrate S-2222 is significantly lower. We have determined the complete amino acid sequence of trocarin. It is a 46,515-Dalton glycoprotein highly homologous to factor Xa and shares the same domain architecture. The light chain possesses an N-terminal Gla domain containing 11 gamma-carboxyglutamic acid residues, followed by two epidermal growth factor (EGF)-like domains; the heavy chain is a serine proteinase. Both chains are likely glycosylated: the light chain at Ser 52 and the heavy chain at Asn 45. Unlike other types of venom procoagulants, trocarin is the first true structural homologue of a coagulation factor. It clots snake plasma and thus may be similar, if not identical, to snake blood coagulation factor Xa. Unlike blood factor Xa, it is expressed in high quantities and in a nonhepatic tissue, making snake venom the richest source of factor Xa-like proteins. It induces cyanosis and death in mice at 1 mg/kg body weight. Thus, trocarin acts as a toxin in venom and a similar, if not identical, protein plays a critical role in hemostasis. (+info)Comparison and recovery of Escherichia coli and thermotolerant coliforms in water with a chromogenic medium incubated at 41 and 44.5 degrees C. (4/413)
This study compared the performance of a commercial chromogenic medium, CHROMagarECC (CECC), and CECC supplemented with sodium pyruvate (CECCP) with the membrane filtration lauryl sulfate-based medium (mLSA) for enumeration of Escherichia coli and non-E. coli thermotolerant coliforms (KEC). To establish that we could recover the maximum KEC and E. coli population, we compared two incubation temperature regimens, 41 and 44.5 degrees C. Statistical analysis by the Fisher test of data did not demonstrate any statistically significant differences (P = 0.05) in the enumeration of E. coli for the different media (CECC and CECCP) and incubation temperatures. Variance analysis of data performed on KEC counts showed significant differences (P = 0.01) between KEC counts at 41 and 44.5 degrees C on both CECC and CECCP. Analysis of variance demonstrated statistically significant differences (P = 0.05) in the enumeration of total thermotolerant coliforms (TTCs) on CECC and CECCP compared with mLSA. Target colonies were confirmed to be E. coli at a rate of 91.5% and KEC of likely fecal origin at a rate of 77.4% when using CECCP incubated at 41 degrees C. The results of this study showed that CECCP agar incubated at 41 degrees C is efficient for the simultaneous enumeration of E. coli and KEC from river and marine waters. (+info)Thrombin mutants with altered enzymatic activity have an impaired mitogenic effect on mouse fibroblasts and are inefficient modulators of stellation of rat cortical astrocytes. (5/413)
We produced recombinant human thrombin mutants to investigate the correlation between the thrombin enzyme and mitogenic activity. Single amino acid substitutions were introduced in the catalytic triad (H43N, D99N, S205A, S205T), in the oxy-anion binding site (G203A) and in the anion binding exosite-1 region (R73E). Proteins were produced as prethrombin-2 mutants secreted in the culture medium of DXB11-derived cell lines. All mutants were activated by ecarin to the corresponding thrombin mutants; the enzymatic activity was assayed on a chromogenic substrate and on the procoagulant substrate fibrinogen. Mutations S205A and G203A completely abolished the enzyme activity. Mutations H43N, D99N and S205T dramatically impaired the enzyme activity toward both substrates. The R73E mutation dissociated the amidolytic activity and the clotting activity of the protein. The ability of thrombin mutants to induce proliferation was investigated in NIH3T3 mouse fibroblasts and rat cortical astrocytes. The ability of the thrombin mutants to revert astrocyte stellation was also studied. The mitogenic activity and the effect on the astrocyte stellation of the thrombin mutants correlated with their enzymatic activity. Furthermore the receptor occupancy by the inactive S205A mutant prevented the thrombin effects providing strong evidence that a proteolytically activated receptor is involved in cellular responses to thrombin. (+info)Requirement for a different hydrophobic moiety and reliable chromogenic substrate for endo-type glycosylceramidases. (6/413)
A series of synthetic lactosides with aglycones that differed in length and structure were used to determine the substrate specificity of endo-type glycosylceramidases. Endoglycoceramidases (EGCase) from bacteria preferred lactosides with an acylamide structure over simple n-alkyl lactosides. While ceramide glycanase (CGase) from leech did not show preference. N -Acylaminoethyl beta-lactosides and n -alkyl lactosides were substrates for both EGCase and CGase, but N-acylaminobutyl beta-lactosides, whose acylamide residue differs from that in ceramide, were not hydrolyzed by EGCases. Thus, EGCases, but not CGase, appear to require an N-acyl group at the same position as that of intact glycosphingolipid for substrate recognition. A p-nitrophenyl lactoside derivative possessing an N-acyl chain was degraded by both EGCases and CGase and this chromogenic substrate may be an alternative substrate for endo-type glycosylceramidase activity. Km of the chromogenic lactoside for CGase and Rhodococcus EGCase were 28 microM and 2.9 mM, respectively. (+info)Ultrastructural localization of light-induced lipid peroxides in the rat retina. (7/413)
PURPOSE: Localization of light-induced lipid peroxides in the rat retina at an ultrastructural level as benzidine-reactive substances. METHODS: Long-Evans rats with nondilated pupils were exposed to intense light of 6000 lux for 12 or 24 hours. Control animals were kept under physiological light conditions. Rats with dilated pupils were exposed to a light intensity of 50 lux or 150,000 lux for 1 hour. For ultrastructural localization the enucleated eyes were fixed in a 0.1-M cacodylate buffer (pH 7.4) containing 2% glutaraldehyde for 2 hours. Pieces of the superior part of the central eyecup were incubated overnight with tetramethylbenzidine (TMB; pH 3.0) at 4 degrees C, postfixed with 1.5% OSO4, and embedded for electron microscopy. RESULTS: In animals exposed to intense light, electron-dense structures appeared exclusively throughout the rod outer segments after an irradiation of 6000 lux for 24 hours or 150,000 lux for 1 hour and were absent in animals with nondilated pupils kept at physiological light conditions. Dilation of the pupils leads to the appearance of electron-dense structures after just 1 hour of 50 lux, whereas rats with nondilated pupils withstand even a 12-hour irradiation with 6000 lux. No electron-dense structures were found when no TMB was used in incubation. CONCLUSIONS: The appearance of electron-dense structures in the rod outer segments depends on the incubation with TMB and intensive light exposure of the rat. Dilation of the pupils lowers the threshold for the emergence of electron-dense structures significantly. This strongly supports the view that light-induced lipid peroxides in the rat retina are localized at an ultrastructural level as benzidine-reactive substances. This protocol presents a tool for the generation and ultrastructural localization of lipid peroxides in rat retinas. (+info)Inhibition of rat vascular smooth muscle cell proliferation in vitro and in vivo by recombinant replication-competent herpes simplex virus. (8/413)
BACKGROUND AND PURPOSE: The proliferation of vascular smooth muscle cells (VSMCs) is a common feature associated with vascular proliferative disorders such as atherosclerosis and restenosis after balloon angioplasty. We examined the antiproliferative effects of recombinant replication-competent herpes simplex virus (HSV), hrR3, to proliferative VSMCs both in vitro and in vivo. METHODS: Early passages of Sprague-Dawley rat VSMCs were infected with hrR3 at a low multiplicity of infection (0.01 to 1.0) to examine the in vitro cytotoxic activity of this recombinant HSV to VSMCs in a proliferative state. Sprague-Dawley rats underwent balloon dilatation injury of the left carotid artery to induce neointimal formation. The injured carotid arteries were infected with hrR3 five days after balloon injury. Two weeks after injury, the left carotid arteries were fixed, and the areas of the neointimal and medial layers were analyzed microscopically. Because the reporter Escherichia coli lacZ gene in hrR3 is expressed only in infected cells in which the virus is actively replicating, virus replication was confirmed by X-gal staining. RESULTS: A morphometric analysis revealed that there were significant differences in the intima/media ratio between the HSV-treated group and mock-infected group (0. 354+/-0.068 and 1.08+/-0.055, respectively). In the histological study (X-gal staining), positive X-gal staining was observed chiefly in the VSMCs in the medial layer just beneath the internal elastic lamina, indicating active viral replication. CONCLUSIONS: Virus-mediated cytocidal therapy using recombinant HSV vector is a promising modality for the treatment of the restenosis after balloon angioplasty. (+info)Chromogenic compounds are substances that can be converted into a colored product through a chemical reaction. These compounds are often used in various diagnostic tests, including microbiological assays and immunoassays, to detect the presence or absence of a specific analyte (such as a particular bacterium, enzyme, or antigen).
In these tests, a chromogenic substrate is added to the sample, and if the target analyte is present, it will react with the substrate and produce a colored product. The intensity of the color can often be correlated with the amount of analyte present in the sample, allowing for quantitative analysis.
Chromogenic compounds are widely used in clinical laboratories because they offer several advantages over other types of diagnostic tests. They are typically easy to use and interpret, and they can provide rapid results with high sensitivity and specificity. Additionally, chromogenic assays can be automated, which can help increase throughput and reduce the potential for human error.
Molecular structure, in the context of biochemistry and molecular biology, refers to the arrangement and organization of atoms and chemical bonds within a molecule. It describes the three-dimensional layout of the constituent elements, including their spatial relationships, bond lengths, and angles. Understanding molecular structure is crucial for elucidating the functions and reactivities of biological macromolecules such as proteins, nucleic acids, lipids, and carbohydrates. Various experimental techniques, like X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and cryo-electron microscopy (cryo-EM), are employed to determine molecular structures at atomic resolution, providing valuable insights into their biological roles and potential therapeutic targets.
Sulfur compounds refer to chemical substances that contain sulfur atoms. Sulfur can form bonds with many other elements, including carbon, hydrogen, oxygen, and nitrogen, among others. As a result, there is a wide variety of sulfur compounds with different structures and properties. Some common examples of sulfur compounds include hydrogen sulfide (H2S), sulfur dioxide (SO2), and sulfonic acids (R-SO3H).
In the medical field, sulfur compounds have various applications. For instance, some are used as drugs or drug precursors, while others are used in the production of medical devices or as disinfectants. Sulfur-containing amino acids, such as methionine and cysteine, are essential components of proteins and play crucial roles in many biological processes.
However, some sulfur compounds can also be harmful to human health. For example, exposure to high levels of hydrogen sulfide or sulfur dioxide can cause respiratory problems, while certain organosulfur compounds found in crude oil and coal tar have been linked to an increased risk of cancer. Therefore, it is essential to handle and dispose of sulfur compounds properly to minimize potential health hazards.
An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.
I'm sorry for any confusion, but "printing" is not a term that has a specific medical definition. It generally refers to the process of producing text or images by impressing ink onto a surface, such as paper. If you have any questions related to healthcare or medical topics, I would be happy to try and help answer those for you!
In the context of medical terminology, 'color' is not defined specifically with a unique meaning. Instead, it generally refers to the characteristic or appearance of something, particularly in relation to the color that a person may observe visually. For instance, doctors may describe the color of a patient's skin, eyes, hair, or bodily fluids to help diagnose medical conditions or monitor their progression.
For example, jaundice is a yellowing of the skin and whites of the eyes that can indicate liver problems, while cyanosis refers to a bluish discoloration of the skin and mucous membranes due to insufficient oxygen in the blood. Similarly, doctors may describe the color of stool or urine to help diagnose digestive or kidney issues.
Therefore, 'color' is not a medical term with a specific definition but rather a general term used to describe various visual characteristics of the body and bodily fluids that can provide important diagnostic clues for healthcare professionals.
Congo Red is a synthetic diazo dye that is commonly used in histology and pathology for stainings and tests. It is particularly useful in identifying amyloid deposits in tissues, which are associated with various diseases such as Alzheimer's disease, type 2 diabetes, and systemic amyloidosis.
When Congo Red binds to amyloid fibrils, it exhibits a characteristic apple-green birefringence under polarized light microscopy. Additionally, Congo Red stained amyloid deposits show a shift in their emission spectrum when excited with circularly polarized light, a phenomenon known as dichroism. These properties make Congo Red a valuable tool for the diagnosis and study of amyloidosis and other protein misfolding disorders.
It is important to note that Congo Red staining should be performed with care, as it can be toxic and carcinogenic if not handled properly.
I'm sorry for any confusion, but "photography" is not a term typically used in medical definitions. Photography refers to the art, application, or process of creating images by recording light or other electromagnetic radiation, either electronically by means of an image sensor, or chemically by means of a light-sensitive material such as photographic film.
If you're looking for a medical term related to imaging, there are several terms that might be relevant, such as:
1. Radiography: This is a technique using X-rays to visualize the internal structures of the body.
2. Ultrasonography: Also known as ultrasound, this is a diagnostic imaging technique using high-frequency sound waves to create images of the inside of the body.
3. Computed Tomography (CT): A type of imaging that uses X-rays to create detailed cross-sectional images of the body.
4. Magnetic Resonance Imaging (MRI): A type of imaging that uses magnetic fields and radio waves to create detailed images of the organs and tissues within the body.
5. Nuclear Medicine: This is a branch of medical imaging that uses small amounts of radioactive material to diagnose and treat diseases.
If you have any questions related to medical definitions or topics, feel free to ask!
I'm sorry for any confusion, but "Silver" is not a medical term. It is a chemical element with the symbol Ag and atomic number 47. Silver is a soft, white, lustrous transition metal that occurs in its pure, free form (native silver) as an alloy with gold and other metals, and in minerals such as argentite and chlorargyrite.
In the medical field, silver compounds have been used for their antimicrobial properties. For example, silver sulfadiazine is a common topical cream used to prevent or treat wound infections. Colloidal silver, a suspension of silver particles in a liquid, has also been promoted as a dietary supplement and alternative treatment for various conditions, but its effectiveness and safety are not well-established.
MedlinePlus is not a medical term, but rather a consumer health website that provides high-quality, accurate, and reliable health information, written in easy-to-understand language. It is produced by the U.S. National Library of Medicine, the world's largest medical library, and is widely recognized as a trusted source of health information.
MedlinePlus offers information on various health topics, including conditions, diseases, tests, treatments, and wellness. It also provides access to drug information, medical dictionary, and encyclopedia, as well as links to clinical trials, medical news, and patient organizations. The website is available in both English and Spanish and can be accessed for free.
Chromogenic print
Madeleine M. Joullié
Chromogenic photography
Indicator bacteria
Formazan
Para-Nitrophenylphosphate
3-Amino-9-ethylcarbazole
Cellulase
Spectrophotometry
Lucien Cuénot
List of MeSH codes (D27)
Tooth whitening
Fecal coliform
Julolidine
Photographic fixer
3,3',5,5'-Tetramethylbenzidine
Yttrium hydride
Chlorophenol red
Nitrocefin
Jerome Horwitz
Smart material
Tooth discoloration
P-Dimethylaminocinnamaldehyde
Nitro blue tetrazolium chloride
Ionochromism
Chromogen
Ergot
Horseradish peroxidase
Claviceps purpurea
Indole
WTS database | WHO FCTC
Chromogenic print - Wikipedia
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Assays7
- The most widely used assays involve VWF peptide substrates and either chromogenic ELISA or FRET techniques, although chemiluminescence assays and rapid screening tests have recently become available. (okstate.edu)
- Cell cytotoxicity assays measure the ability of certain compounds or chemical mediators to reduce the viability of the cells. (labettor.com)
- Liquid samples: A convenient sample volume is two milliliters for the turbidimetric and chromogenic assays and four milliliters for the gel-clot assay. (acciusa.com)
- Coagulation tests can be broadly divided into clot-based and chromogenic assays.1 In both techniques, whole-blood samples are centrifuged to obtain platelet-poor plasma. (openanesthesia.org)
- Chromogenic assays use specific factor substrates bound to a chromophore and release a colored compound when cleaved proportionally to the amount of factor present. (openanesthesia.org)
- Clotting and chromogenic assays utilising Echis carinatus venom were set up to determine the total prothrombin-related material (PRM) in plasma and liver fractions. (le.ac.uk)
- Herein the identification of an inexpensive and stable chromogenic substrate suitable for use in assays of clinically relevant MBLs is described. (ox.ac.uk)
Substrate6
- The most commonly used methodology is the chromogenic assay, which uses a chromophore-linked substrate of factor Xa. (medscape.com)
- Upon cleavage of the substrate by the active enzyme (factor Xa), a colored compound is released. (medscape.com)
- In addition to possessing identical sequence specificity of cleavage (Ile-Glu-Gly-Arg ) to factor Xa on prothrombin, the macromolecular physiological substrate, notanarin also specifically hydrolyzes a number of factor Xa-specific chromogenic substrates such as CH3SO2-D-leucyl-glycyl-L-arginine-p-nitroanilide and N-benzoyl-L-isoleucyl-L-glutamyl-(piperidyl)-glycyl-L-arginyl-p-nitroanilide hydrochloride. (venomsupplies.com)
- This was achieved by the developed chromatographic setup, including a fluorogenic instead of chromogenic substrate. (altex.org)
- Chromogenic activity is a result of a chromogenic substrate for the detection of the β-glucosidase enzyme, common to all Listeria spp. (thermalindo.com)
- This enzyme hydrolyzes the chromogenic substrate: TMB, to form a colored compound whose reaction will be stopped by sulfuric acid. (cryopep.com)
Substrates3
- Display our full list of chromogenic substrates . (megazyme.com)
- New chromogenic substrates for the assay of alpha-amylase and (1→4)-β-D-glucanase. (megazyme.com)
- With a Δλmax value of 100 nm between the parent and hydrolysis product, a higher analytical accuracy is possible with CLS405 than with commonly used chromogenic substrates. (ox.ac.uk)
Assay6
- In this study, we developed a high-throughput fluorogenic assay to evaluate the inhibitory activity of various compounds on BLV protease, an essential enzyme for viral replication. (bvsalud.org)
- Additionally, the anti-BLV activity of both compounds was evaluated using a cell-based assay, and mitorubrinic acid was found to exhibit inhibitory activity without cytotoxicity. (bvsalud.org)
- Non-finished products may be shipped in any container that does not adsorb endotoxin or produce compounds that may interfere with the assay. (acciusa.com)
- After the candidate compound is mixed with the target, the interaction between the compound and the target can be quantitatively determined by enzyme-linked immunoassay, fluorescence chromogenic assay, nuclear magnetic resonance, and other methods, thus becoming the basis for compound screening. (bocsci.com)
- The chromogenic assay revealed an increase in the PRM of microsomes prepared from warfarin-treated rats, reflecting a build-up of prothrombin precursors. (le.ac.uk)
- The chromogenic assay was not only useful for the determination of PRM in turbid samples. (le.ac.uk)
Dyes5
- Chromogenic processes are characterized by a reaction between two chemicals to create the color dyes that make up a print. (wikipedia.org)
- The aim of this work was the design, synthesis, and characterization of new chromogenic spirolactone dyes based on a 2-phenyl-1-benzopyrylium (flavylium) backbone for further development of thermochromic smart labels. (unl.pt)
- The dyes that have electron-withdrawing groups attached, such as cyano, display stronger chromogenic effects useful for future applications. (unl.pt)
- The formazan dyes are chromogenic products formed by the reduction of tetrazolium salts by dehydrogenases, such as lactate dehydrogenase (LDH) and reductases that are released during cell death. (labettor.com)
- A protocol for establishing the suitability of chromogenic dyes in the analysis of filamentous fungi with phenotype microarrays was described. (edu.pl)
Enzyme1
- Combining both the chromogenic and phospholipase enzyme reactions makes it possible to differentiate Listeria monocytogenes (blue colonies surrounded by an opaque halo) from other Listeria spp. (thermalindo.com)
Fluorogenic1
- Pregabalin, as a primary amine compound, reacts with 7-chloro-4-nitrobenzofurazon (NBD-Cl) which is a highly sensitive fluorogenic and chromogenic reagent used in many investigations. (istanbul.edu.tr)
Reagent2
- TMBZ is a chromogenic reagent utilized for peroxidase detection. (dojindo.com)
- The Sakura Finetek Usa Tissue-Tek O.C.T. Compound reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. (biolisp.org)
Endotoxin1
- Samples were analyzed for levels of bacterial endotoxin via chromogenic limulus amebocyte lysate, crystalline silica via X-ray diffraction, and 20 metals via inductively coupled plasma/mass spectrometry. (cdc.gov)
Bacteria2
- No study on the antibacterial effects of VCO on the chromogenic bacteria that causes dental black stains. (innovareacademics.in)
- The findings of this study provide both a useful tool compound for further inhibitor identification, and novel scaffolds for the design of improved MBL inhibitors with potential as antibiotics against resistant strains of bacteria. (ox.ac.uk)
Acid5
- With its multiple health benefits, chromogenic acid targets overweight issues and high blood pressure. (whatmojo.com)
- Lithium chloride in the base medium and supplementary antimicrobial compounds ceftazidime, polymyxin, nalidixic acid, and cycloheximide provide the medium's selectivity. (thermalindo.com)
- The active ingredient is a compound called hydroxycitric acid (HCA). (dietpillbuyer.com)
- In their raw (green) state coffee beans contain a compound called chlorogenic acid, but when they are exposed to heat the chromogenic acid is lost, as are the benefits it can provide. (dietpillbuyer.com)
- A number of studies show the chromogenic acid in green coffee beans can boost the metabolism and provide thermogenic fat burning. (dietpillbuyer.com)
Detection1
- The cellular level of drug screening is a drug screening model that is closer to the physiological condition, the model is proposed to design drug target cells, and the application of cell culture technology to obtain the required cells, these cells interact with candidate compounds, by screening and biochemical levels similar detection technology was developed for the determination of compound action ability, filtered by the compound. (bocsci.com)
Antibiotics1
- Each device contains a chromogenic liquid media formulated with antibiotics, growth enhancers, and color-changing compounds specific to Listeria species. (jjstech.com)
Peroxidase1
- The subject ANS analogs are characterized in that they react with MBTH or analogs thereof in the presence of an oxidizing agent, a peroxidase and oxygen to produce a chromogenic, specifically a blue, reaction product that exhibits reduced drift. (allindianpatents.com)
Determination1
- 1963) Tables of Spectrophotometric Absorption Data of Compounds Used for the Colorimetric Determination of Elements. (photochemcad.com)
Specificity2
- Selectivity and specificity of a chromogenic medium for detecting Vibrio parahaemolyticust. (oregonstate.edu)
- This study examined the selectivity and specificity of Bio-Chrome Vibrio medium (BCVM), a chromogenic medium that detects V. parahaemolyticus on the basis of the formation of distinct purple colonies on the medium. (oregonstate.edu)
Inhibit2
- Previous studies showed that different plant-derived flavonoid compounds could stimulate osteoblasts function, and inhibit osteoclasts functions either alone or in combination. (biomedcentral.com)
- The structurally related compound, PP493, was found to inhibit vitamin K-dependent carboxylation in both solubilised and non-solubilised microsomes. (le.ac.uk)
Evaluate2
Ultraviolet3
- The compound has an unusual ultraviolet spectrum, and the color change can be followed quantitatively by measuring changes in absorption which occur in the 380- to 500-nm region, where cephalosporins normally have no absorption. (nih.gov)
- Friedel, R. A. and M. Orchin (1951) Ultraviolet Spectra of Aromatic Compounds. (photochemcad.com)
- Hirayama, K. (1967) Handbook of Ultraviolet and Visible Absorption Spectra of Organic Compounds. (photochemcad.com)
Species1
- The synthesized compounds can switch between two species if the appropriate conditions are used. (unl.pt)
Analysis2
- In This Edition Chromatography Articles - Faster and automated analysis of aroma compounds in cosmetics Mass Spectrometry & Spectroscopy Articles - Frequently Asked Questions (FAQ) abou. (labmate-online.com)
- Faster and automated analysis of aroma compound. (labmate-online.com)
Medium3
- Notwithstanding the success of chromogenic prints in the amateur and professional market, it wasn't considered a medium for fine-art photography up to the 1970s. (wikipedia.org)
- Their works, and those of many others, caused chromogenic prints to become the preferred medium for contemporary photography by the 1990s. (wikipedia.org)
- New Chromogenic Uti Medium is Launched: New Clarity Agar Improves Differ. (labmate-online.com)
Factor2
- Description: Compound 56, 4-[(3-Bromophenyl)amino]-6,7-diethoxyquinazoline, is a potent and specific inhibitor of the tyrosine kinase of the epidermal growth factor receptor (EGFR) showing an IC50 of 0.006 nM. (biolisp.org)
- A phenotypic female with a low level of factor VIII or factor IX may be classified into one of the following categories of causality: homozygosity (two identical haemophilia alleles), compound heterozygosity (two different haemophilia alleles), hemizygosity (one haemophilia allele and no normal allele), heterozygosity (one haemophilia allele and one normal allele), genetic causes other than haemophilia and non-genetic causes. (cdc.gov)
Activity3
- Drug screening is a step in the modern drug development process to test and obtain compounds with specific physiological activity. (bocsci.com)
- It refers to the process of selecting compounds with high activity for a specific target from a large number of compounds or new compounds by standardized experimental means. (bocsci.com)
- Drug development costs can be greatly reduced by predicting the likely activity of compounds and then conducting targeted entity screening of compounds that are more likely to become drugs. (bocsci.com)
Common2
- Chromogenic prints made from negatives became obsolete with the release of chromogenic digital prints, which have become the most common photographic print today. (wikipedia.org)
- The common structural feature of these compounds is the presence of an azomethine group, linked by a η methyl-ene bridge, which can act as a hydrogen-bond acceptor. (iucr.org)
Color7
- A chromogenic print, also known as a C-print or C-type print, a silver halide print, or a dye coupler print, is a photographic print made from a color negative, transparency or digital image, and developed using a chromogenic process. (wikipedia.org)
- The potential of oxidized developers in a color photographic process however, was first realized by another German chemist, Rudolf Fischer, who, in 1912, filed a patent describing a chromogenic process to develop both positives and negatives using indoxyl, and thio-indoxyl-based color developers as dye couplers in a light-sensitive silver halide emulsion. (wikipedia.org)
- 698 Agfa patented both the developer for this print and its photographic process, and promptly developed and released in 1936 Agfacolor Neu, the first chromogenic print, which was a color print film that could be developed using a transparency. (wikipedia.org)
- In 1942, Kodak released Kodacolor, the first published chromogenic color print film that could be developed from a negative. (wikipedia.org)
- In 1955, Kodak introduced a chromogenic paper named "Type C", which was the first color negative paper Kodak sold to other labs and individual photographers. (wikipedia.org)
- The pioneers in the use of chromogenic prints and in the use of color photography as a whole in fine-art were photographers such as Ernst Haas, which was profiled by the Museum of Modern Art in its first exhibition of color photography in 1962. (wikipedia.org)
- 257 Other pioneering fine-art color photographers who printed their photographs on chromogenic prints include William Eggleston:251 and Stephen Shore. (wikipedia.org)
Price1
- Due to their simple development process and their cheap price, chromogenic printing became wildly popular in amateur photography, and by the 1960s it overtook black and white printing in the amateur photofinishing market. (wikipedia.org)
Sample1
- Consequently, higher levels of LMWH or UH in the sample lead to lower chromogenic intensity. (medscape.com)
Paper2
- 698 Agfa developed a chromogenic negative film by 1939, which could be developed directly on a companion paper to the film, although this film was never commercialized. (wikipedia.org)
- Although the paper's name was changed to "Kodak Ektacolor Paper" in 1958, the terminology "Type-C Print" persisted, and has become a popular term for chromogenic prints made from negatives still in use today, with the name "Type-R Print" becoming its reversal film counterpart. (wikipedia.org)
Process1
- The anti-oxidant capacity of the compound was determined by the cupric reducing anti-oxidant capacity (CUPRAC) process. (iucr.org)
Data1
- CRC Atlas of Spectral Data and Physical Constants for Organic Compounds. (photochemcad.com)