Cell Death: The termination of the cell's ability to carry out vital functions such as metabolism, growth, reproduction, responsiveness, and adaptability.Cause of Death: Factors which produce cessation of all vital bodily functions. They can be analyzed from an epidemiologic viewpoint.Death: Irreversible cessation of all bodily functions, manifested by absence of spontaneous breathing and total loss of cardiovascular and cerebral functions.Death, Sudden, Cardiac: Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)Brain Death: A state of prolonged irreversible cessation of all brain activity, including lower brain stem function with the complete absence of voluntary movements, responses to stimuli, brain stem reflexes, and spontaneous respirations. Reversible conditions which mimic this clinical state (e.g., sedative overdose, hypothermia, etc.) are excluded prior to making the determination of brain death. (From Adams et al., Principles of Neurology, 6th ed, pp348-9)Fetal Death: Death of the developing young in utero. BIRTH of a dead FETUS is STILLBIRTH.Attitude to Death: Conceptual response of the person to the various aspects of death, which are based on individual psychosocial and cultural experience.Caspases: A family of intracellular CYSTEINE ENDOPEPTIDASES that play a role in regulating INFLAMMATION and APOPTOSIS. They specifically cleave peptides at a CYSTEINE amino acid that follows an ASPARTIC ACID residue. Caspases are activated by proteolytic cleavage of a precursor form to yield large and small subunits that form the enzyme. Since the cleavage site within precursors matches the specificity of caspases, sequential activation of precursors by activated caspases can occur.Apoptosis: One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.Receptors, Death Domain: A family of cell surface receptors that signal via a conserved domain that extends into the cell CYTOPLASM. The conserved domain is referred to as a death domain due to the fact that many of these receptors are involved in signaling APOPTOSIS. Several DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS can bind to the death domains of the activated receptors and through a complex series of interactions activate apoptotic mediators such as CASPASES.Cell Survival: The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Mortality: All deaths reported in a given population.Autopsy: Postmortem examination of the body.Caspase 3: A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 9. Isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.Necrosis: The pathological process occurring in cells that are dying from irreparable injuries. It is caused by the progressive, uncontrolled action of degradative ENZYMES, leading to MITOCHONDRIAL SWELLING, nuclear flocculation, and cell lysis. It is distinct it from APOPTOSIS, which is a normal, regulated cellular process.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Proto-Oncogene Proteins c-bcl-2: Membrane proteins encoded by the BCL-2 GENES and serving as potent inhibitors of cell death by APOPTOSIS. The proteins are found on mitochondrial, microsomal, and NUCLEAR MEMBRANE sites within many cell types. Overexpression of bcl-2 proteins, due to a translocation of the gene, is associated with follicular lymphoma.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Signal Transduction: The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.Antigens, CD95: A tumor necrosis factor receptor subtype found in a variety of tissues and on activated LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.Mitochondria: Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)Infant, Newborn: An infant during the first month after birth.DNA Fragmentation: Splitting the DNA into shorter pieces by endonucleolytic DNA CLEAVAGE at multiple sites. It includes the internucleosomal DNA fragmentation, which along with chromatin condensation, are considered to be the hallmarks of APOPTOSIS.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Survival Analysis: A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.Cell Line, Tumor: A cell line derived from cultured tumor cells.Caspase Inhibitors: Endogenous and exogenous compounds and that either inhibit CASPASES or prevent their activation.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Autophagy: The segregation and degradation of damaged or unwanted cytoplasmic constituents by autophagic vacuoles (cytolysosomes) composed of LYSOSOMES containing cellular components in the process of digestion; it plays an important role in BIOLOGICAL METAMORPHOSIS of amphibians, in the removal of bone by osteoclasts, and in the degradation of normal cell components in nutritional deficiency states.In Situ Nick-End Labeling: An in situ method for detecting areas of DNA which are nicked during APOPTOSIS. Terminal deoxynucleotidyl transferase is used to add labeled dUTP, in a template-independent manner, to the 3 prime OH ends of either single- or double-stranded DNA. The terminal deoxynucleotidyl transferase nick end labeling, or TUNEL, assay labels apoptosis on a single-cell level, making it more sensitive than agarose gel electrophoresis for analysis of DNA FRAGMENTATION.Caspase 8: A long pro-domain caspase that contains a death effector domain in its pro-domain region. Caspase 8 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS.Infant Mortality: Postnatal deaths from BIRTH to 365 days after birth in a given population. Postneonatal mortality represents deaths between 28 days and 365 days after birth (as defined by National Center for Health Statistics). Neonatal mortality represents deaths from birth to 27 days after birth.Death Domain Receptor Signaling Adaptor Proteins: Intracellular signaling adaptor proteins that bind to the cytoplasmic death domain region found on DEATH DOMAIN RECEPTORS. Many of the proteins in this class take part in intracellular signaling from TUMOR NECROSIS FACTOR RECEPTORS.Cohort Studies: Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.BH3 Interacting Domain Death Agonist Protein: A member of the Bcl-2 protein family that reversibly binds MEMBRANES. It is a pro-apoptotic protein that is activated by caspase cleavage.Neurons: The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.United Statesbcl-2-Associated X Protein: A member of the Bcl-2 protein family and homologous partner of C-BCL-2 PROTO-ONCOGENE PROTEIN. It regulates the release of CYTOCHROME C and APOPTOSIS INDUCING FACTOR from the MITOCHONDRIA. Several isoforms of BCL2-associated X protein occur due to ALTERNATIVE SPLICING of the mRNA for this protein.Prognosis: A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.Survival Rate: The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.Reactive Oxygen Species: Molecules or ions formed by the incomplete one-electron reduction of oxygen. These reactive oxygen intermediates include SINGLET OXYGEN; SUPEROXIDES; PEROXIDES; HYDROXYL RADICAL; and HYPOCHLOROUS ACID. They contribute to the microbicidal activity of PHAGOCYTES, regulation of signal transduction and gene expression, and the oxidative damage to NUCLEIC ACIDS; PROTEINS; and LIPIDS.Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Age Factors: Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.Caspase 9: A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspase 9 is activated during cell stress by mitochondria-derived proapoptotic factors and by CARD SIGNALING ADAPTOR PROTEINS such as APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.Fas Ligand Protein: A transmembrane protein belonging to the tumor necrosis factor superfamily that was originally discovered on cells of the lymphoid-myeloid lineage, including activated T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS.Enzyme Activation: Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme.Incidence: The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.Cell Line: Established cell cultures that have the potential to propagate indefinitely.Amino Acid Chloromethyl Ketones: Inhibitors of SERINE ENDOPEPTIDASES and sulfhydryl group-containing enzymes. They act as alkylating agents and are known to interfere in the translation process.Homicide: The killing of one person by another.Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).Registries: The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.Mice, Inbred C57BLSuicide: The act of killing oneself.Cytochromes c: Cytochromes of the c type that are found in eukaryotic MITOCHONDRIA. They serve as redox intermediates that accept electrons from MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX III and transfer them to MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX IV.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Maternal Mortality: Maternal deaths resulting from complications of pregnancy and childbirth in a given population.Cysteine Proteinase Inhibitors: Exogenous and endogenous compounds which inhibit CYSTEINE ENDOPEPTIDASES.Kaplan-Meier Estimate: A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)Poly(ADP-ribose) Polymerases: Enzymes that catalyze the transfer of multiple ADP-RIBOSE groups from nicotinamide-adenine dinucleotide (NAD) onto protein targets, thus building up a linear or branched homopolymer of repeating ADP-ribose units i.e., POLY ADENOSINE DIPHOSPHATE RIBOSE.bcl-X Protein: A member of the bcl-2 protein family that plays a role in the regulation of APOPTOSIS. Two major isoforms of the protein exist due to ALTERNATIVE SPLICING of the BCL2L1 mRNA and are referred to as Bcl-XS and Bcl-XL.bcl-Associated Death Protein: A pro-apoptotic protein and member of the Bcl-2 protein family that is regulated by PHOSPHORYLATION. Unphosphorylated Bad protein inhibits the activity of BCL-XL PROTEIN.Blotting, Western: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.Risk: The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Wounds and Injuries: Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity.Mice, Knockout: Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.Programmed Cell Death 1 Receptor: An inhibitory T-lymphocyte receptor that has specificity for CD274 ANTIGEN and PROGRAMMED CELL DEATH 1 LIGAND 2 PROTEIN. Signaling by the receptor limits T cell proliferation and INTERFERON GAMMA synthesis. The receptor also may play an essential role in the regulatory pathway that induces PERIPHERAL TOLERANCE.Life Expectancy: Based on known statistical data, the number of years which any person of a given age may reasonably expected to live.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Antineoplastic Agents: Substances that inhibit or prevent the proliferation of NEOPLASMS.Receptors, TNF-Related Apoptosis-Inducing Ligand: Tumor necrosis factor receptor family members that are widely expressed and play a role in regulation of peripheral immune responses and APOPTOSIS. The receptors are specific for TNF-RELATED APOPTOSIS-INDUCING LIGAND and signal via conserved death domains that associate with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.TNF-Related Apoptosis-Inducing Ligand: A transmembrane-protein belonging to the TNF family of intercellular signaling proteins. It is a widely expressed ligand that activates APOPTOSIS by binding to TNF-RELATED APOPTOSIS-INDUCING LIGAND RECEPTORS. The membrane-bound form of the protein can be cleaved by specific CYSTEINE ENDOPEPTIDASES to form a soluble ligand form.Tumor Cells, Cultured: Cells grown in vitro from neoplastic tissue. If they can be established as a TUMOR CELL LINE, they can be propagated in cell culture indefinitely.Models, Biological: Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.Tumor Suppressor Protein p53: Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.Enzyme Inhibitors: Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.Proto-Oncogene Proteins: Products of proto-oncogenes. Normally they do not have oncogenic or transforming properties, but are involved in the regulation or differentiation of cell growth. They often have protein kinase activity.Vital Statistics: Used for general articles concerning statistics of births, deaths, marriages, etc.Membrane Potential, Mitochondrial: The voltage difference, normally maintained at approximately -180mV, across the INNER MITOCHONDRIAL MEMBRANE, by a net movement of positive charge across the membrane. It is a major component of the PROTON MOTIVE FORCE in MITOCHONDRIA used to drive the synthesis of ATP.Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.Sex Factors: Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.Hospitalization: The confinement of a patient in a hospital.Tumor Necrosis Factor-alpha: Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.Multivariate Analysis: A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.Receptors, Tumor Necrosis Factor: Cell surface receptors that bind TUMOR NECROSIS FACTORS and trigger changes which influence the behavior of cells.Asphyxia: A pathological condition caused by lack of oxygen, manifested in impending or actual cessation of life.Transfection: The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.Jurkat Cells: A CELL LINE derived from human T-CELL LEUKEMIA and used to determine the mechanism of differential susceptibility to anti-cancer drugs and radiation.RNA, Small Interfering: Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions.Flow Cytometry: Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.Cell Proliferation: All of the processes involved in increasing CELL NUMBER including CELL DIVISION.EnglandPopulation Surveillance: Ongoing scrutiny of a population (general population, study population, target population, etc.), generally using methods distinguished by their practicability, uniformity, and frequently their rapidity, rather than by complete accuracy.Hydrogen Peroxide: A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.Terminal Care: Medical and nursing care of patients in the terminal stage of an illness.Bereavement: Refers to the whole process of grieving and mourning and is associated with a deep sense of loss and sadness.Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)Neuroprotective Agents: Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.Receptor-Interacting Protein Serine-Threonine Kinases: A family of serine-threonine kinases that plays a role in intracellular signal transduction by interacting with a variety of signaling adaptor proteins such as CRADD SIGNALING ADAPTOR PROTEIN; TNF RECEPTOR-ASSOCIATED FACTOR 2; and TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN. Although they were initially described as death domain-binding adaptor proteins, members of this family may contain other protein-binding domains such as those involving caspase activation and recruitment.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Mice, Transgenic: Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.Mortality, Premature: Deaths that occur before LIFE EXPECTANCY is reached within a given population.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Carrier Proteins: Transport proteins that carry specific substances in the blood or across cell membranes.DNA Damage: Injuries to DNA that introduce deviations from its normal, intact structure and which may, if left unrepaired, result in a MUTATION or a block of DNA REPLICATION. These deviations may be caused by physical or chemical agents and occur by natural or unnatural, introduced circumstances. They include the introduction of illegitimate bases during replication or by deamination or other modification of bases; the loss of a base from the DNA backbone leaving an abasic site; single-strand breaks; double strand breaks; and intrastrand (PYRIMIDINE DIMERS) or interstrand crosslinking. Damage can often be repaired (DNA REPAIR). If the damage is extensive, it can induce APOPTOSIS.Accidents, Traffic: Accidents on streets, roads, and highways involving drivers, passengers, pedestrians, or vehicles. Traffic accidents refer to AUTOMOBILES (passenger cars, buses, and trucks), BICYCLING, and MOTORCYCLES but not OFF-ROAD MOTOR VEHICLES; RAILROADS nor snowmobiles.Cytoprotection: The process by which chemical compounds provide protection to cells against harmful agents.Electrocardiography: Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.Membrane Glycoproteins: Glycoproteins found on the membrane or surface of cells.bcl-2 Homologous Antagonist-Killer Protein: A multi-domain mitochondrial membrane protein and member of the bcl-2 Protein family. Bak protein interacts with TUMOR SUPPRESSOR PROTEIN P53 and promotes APOPTOSIS.Annexin A5: A protein of the annexin family isolated from human PLACENTA and other tissues. It inhibits cytosolic PHOSPHOLIPASE A2, and displays anticoagulant activity.WalesCoronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.Up-Regulation: A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.Fatal Outcome: Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Cell Cycle: The complex series of phenomena, occurring between the end of one CELL DIVISION and the end of the next, by which cellular material is duplicated and then divided between two daughter cells. The cell cycle includes INTERPHASE, which includes G0 PHASE; G1 PHASE; S PHASE; and G2 PHASE, and CELL DIVISION PHASE.Membrane Proteins: Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.Wounds, Gunshot: Disruption of structural continuity of the body as a result of the discharge of firearms.TNF Receptor-Associated Death Domain Protein: A 34 kDa signal transducing adaptor protein that associates with TUMOR NECROSIS FACTOR RECEPTOR TYPE 1. It facilitates the recruitment of signaling proteins such as TNF RECEPTOR-ASSOCIATED FACTOR 2 and FAS ASSOCIATED DEATH DOMAIN PROTEIN to the receptor complex.Poisoning: A condition or physical state produced by the ingestion, injection, inhalation of or exposure to a deleterious agent.Gene Expression Regulation: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.JNK Mitogen-Activated Protein Kinases: A subgroup of mitogen-activated protein kinases that activate TRANSCRIPTION FACTOR AP-1 via the phosphorylation of C-JUN PROTEINS. They are components of intracellular signaling pathways that regulate CELL PROLIFERATION; APOPTOSIS; and CELL DIFFERENTIATION.Recurrence: The return of a sign, symptom, or disease after a remission.Cell Division: The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.Phosphorylation: The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.Inhibitor of Apoptosis Proteins: A conserved class of proteins that control APOPTOSIS in both VERTEBRATES and INVERTEBRATES. IAP proteins interact with and inhibit CASPASES, and they function as ANTI-APOPTOTIC PROTEINS. The protein class is defined by an approximately 80-amino acid motif called the baculoviral inhibitor of apoptosis repeat.Caspase 1: A long pro-domain caspase that has specificity for the precursor form of INTERLEUKIN-1BETA. It plays a role in INFLAMMATION by catalytically converting the inactive forms of CYTOKINES such as interleukin-1beta to their active, secreted form. Caspase 1 is referred as interleukin-1beta converting enzyme and is frequently abbreviated ICE.HeLa Cells: The first continuously cultured human malignant CELL LINE, derived from the cervical carcinoma of Henrietta Lacks. These cells are used for VIRUS CULTIVATION and antitumor drug screening assays.Biological Markers: Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Down-Regulation: A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.Caspase 2: A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its caspase recruitment domain with CARD SIGNALING ADAPTOR PROTEINS. Caspase 2 plays a role in APOPTOSIS by cleaving and activating effector pro-caspases. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.Reverse Transcriptase Polymerase Chain Reaction: A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.Forensic Pathology: The application of pathology to questions of law.Logistic Models: Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.Stillbirth: The event that a FETUS is born dead or stillborn.Disease Progression: The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.Lung Neoplasms: Tumors or cancer of the LUNG.Cell Nucleus: Within a eukaryotic cell, a membrane-limited body which contains chromosomes and one or more nucleoli (CELL NUCLEOLUS). The nuclear membrane consists of a double unit-type membrane which is perforated by a number of pores; the outermost membrane is continuous with the ENDOPLASMIC RETICULUM. A cell may contain more than one nucleus. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.Animals, Newborn: Refers to animals in the period of time just after birth.Caspase 7: A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 3 and CASPASE 10. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.Tissue and Organ Procurement: The administrative procedures involved with acquiring TISSUES or organs for TRANSPLANTATION through various programs, systems, or organizations. These procedures include obtaining consent from TISSUE DONORS and arranging for transportation of donated tissues and organs, after TISSUE HARVESTING, to HOSPITALS for processing and transplantation.Propidium: Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.Cysteine Endopeptidases: ENDOPEPTIDASES which have a cysteine involved in the catalytic process. This group of enzymes is inactivated by CYSTEINE PROTEINASE INHIBITORS such as CYSTATINS and SULFHYDRYL REAGENTS.RNA Interference: A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.NF-kappa B: Ubiquitous, inducible, nuclear transcriptional activator that binds to enhancer elements in many different cell types and is activated by pathogenic stimuli. The NF-kappa B complex is a heterodimer composed of two DNA-binding subunits: NF-kappa B1 and relA.Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).Great BritainCell Count: The number of CELLS of a specific kind, usually measured per unit volume or area of sample.Epidemiologic Methods: Research techniques that focus on study designs and data gathering methods in human and animal populations.Odds Ratio: The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.Gene Expression: The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.Proteins: Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.Apoptotic Protease-Activating Factor 1: A CARD signaling adaptor protein that plays a role in the mitochondria-stimulated apoptosis (APOPTOSIS, INTRINSIC PATHWAY). It binds to CYTOCHROME C in the CYTOSOL to form an APOPTOSOMAL PROTEIN COMPLEX and activates INITIATOR CASPASES such as CASPASE 9.Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.Regression Analysis: Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.Breast Neoplasms: Tumors or cancer of the human BREAST.Staurosporine: An indolocarbazole that is a potent PROTEIN KINASE C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)Cytochrome c Group: A group of cytochromes with covalent thioether linkages between either or both of the vinyl side chains of protoheme and the protein. (Enzyme Nomenclature, 1992, p539)Smoking: Inhaling and exhaling the smoke of burning TOBACCO.Genes, bcl-2: The B-cell leukemia/lymphoma-2 genes, responsible for blocking apoptosis in normal cells, and associated with follicular lymphoma when overexpressed. Overexpression results from the t(14;18) translocation. The human c-bcl-2 gene is located at 18q24 on the long arm of chromosome 18.Neurotoxins: Toxic substances from microorganisms, plants or animals that interfere with the functions of the nervous system. Most venoms contain neurotoxic substances. Myotoxins are included in this concept.Microscopy, Fluorescence: Microscopy of specimens stained with fluorescent dye (usually fluorescein isothiocyanate) or of naturally fluorescent materials, which emit light when exposed to ultraviolet or blue light. Immunofluorescence microscopy utilizes antibodies that are labeled with fluorescent dye.Acute Disease: Disease having a short and relatively severe course.Protein-Serine-Threonine Kinases: A group of enzymes that catalyzes the phosphorylation of serine or threonine residues in proteins, with ATP or other nucleotides as phosphate donors.Life Tables: Summarizing techniques used to describe the pattern of mortality and survival in populations. These methods can be applied to the study not only of death, but also of any defined endpoint such as the onset of disease or the occurrence of disease complications.JapanCalcium: A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.Recombinant Proteins: Proteins prepared by recombinant DNA technology.Comorbidity: The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.Calpain: Cysteine proteinase found in many tissues. Hydrolyzes a variety of endogenous proteins including NEUROPEPTIDES; CYTOSKELETAL PROTEINS; proteins from SMOOTH MUSCLE; CARDIAC MUSCLE; liver; platelets; and erythrocytes. Two subclasses having high and low calcium sensitivity are known. Removes Z-discs and M-lines from myofibrils. Activates phosphorylase kinase and cyclic nucleotide-independent protein kinase. This enzyme was formerly listed as EC Proteins, Signal Transducing: A broad category of carrier proteins that play a role in SIGNAL TRANSDUCTION. They generally contain several modular domains, each of which having its own binding activity, and act by forming complexes with other intracellular-signaling molecules. Signal-transducing adaptor proteins lack enzyme activity, however their activity can be modulated by other signal-transducing enzymesDNA-Binding Proteins: Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.Receptors, Tumor Necrosis Factor, Type I: A tumor necrosis factor receptor subtype that has specificity for TUMOR NECROSIS FACTOR ALPHA and LYMPHOTOXIN ALPHA. It is constitutively expressed in most tissues and is a key mediator of tumor necrosis factor signaling in the vast majority of cells. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.Cerebrovascular Disorders: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.Antioxidants: Naturally occurring or synthetic substances that inhibit or retard the oxidation of a substance to which it is added. They counteract the harmful and damaging effects of oxidation in animal tissues.Tissue Donors: Individuals supplying living tissue, organs, cells, blood or blood components for transfer or transplantation to histocompatible recipients.Child Mortality: Number of deaths of children between one year of age to 12 years of age in a given population.SwedenChi-Square Distribution: A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.Fibroblasts: Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.Microtubule-Associated Proteins: High molecular weight proteins found in the MICROTUBULES of the cytoskeletal system. Under certain conditions they are required for TUBULIN assembly into the microtubules and stabilize the assembled microtubules.Grief: Normal, appropriate sorrowful response to an immediate cause. It is self-limiting and gradually subsides within a reasonable time.Perinatal Mortality: Deaths occurring from the 28th week of GESTATION to the 28th day after birth in a given population.Proto-Oncogene Proteins c-akt: A protein-serine-threonine kinase that is activated by PHOSPHORYLATION in response to GROWTH FACTORS or INSULIN. It plays a major role in cell metabolism, growth, and survival as a core component of SIGNAL TRANSDUCTION. Three isoforms have been described in mammalian cells.

*  Extreme heat can cause death
Michigan averages about four heat-related deaths each year. Here are some hints to prevent heat disorders. #AD_text{ font-size ...
*  Death Cause Undetermined - tribunedigital-sunsentinel
Officials have not yet determined the cause of death of a man who was caught apparently burglarizing a business and subdued by ... GREENACRES CITY -- Officials have not yet determined the cause of death of a man who was caught apparently burglarizing a ... s office after an investigation into the death. Until the investigation is finished, Paikai said, he will only release details ...
*  3303.0 - Causes of Death, Australia, 2013
USE OF MULTIPLE CAUSE OF DEATHS DATA. 96 Multiple causes of death include all causes and conditions reported on the death ... but not the Causes of Death collection. Neonatal deaths are in scope of the Deaths, Causes of Death and Perinatal collections. ... Coverage of causes of death statistics. 12 The ABS Causes of Death collection includes all deaths that occurred and were ... 3302.0) and Retrospective Deaths by Causes of Death, Queensland, 2010, in Causes of Death, Australia, 2010 (cat. no. 3303.0).
http://abs.gov.au/AUSSTATS/abs@.nsf/Lookup/3303.0Explanatory Notes12013?OpenDocument
*  3303.0 - Causes of Death, Australia, 2013
Tables in Causes of Death, Australia, 2013. Underlying causes of death (Australia). 1.1 Underlying cause of death, All causes, ... Multiple causes of death (Australia). 10.1 Multiple causes of death, All causes, Number of deaths by number of causes reported ... Underlying causes of death (Victoria). 3.1 Underlying cause of death, All causes, Victoria, 2013. 3.2 Underlying cause of death ... Underlying causes of death (Tasmania). 7.1 Underlying cause of death, All causes, Tasmania, 2013. 7.2 Underlying
http://abs.gov.au/ausstats/abs@.nsf/INotes/3303.02013Data Cubes?opendocument&TabName=Notes&ProdNo=3303.0&Issue=2013&num=&view=&
*  3303.0 - Causes of Death, Australia, 2010
Diseases of the Digestive System (K00-K93) were the underlying cause of death for 145 Aboriginal and Torres Strait Islander ... with 95 deaths in 2010. The age standardised death rate for Diseases of the Liver was almost five times higher (rate ratio of ... of deaths.. The most common type of digestive disease that contributed to Aboriginal and Torres Strait Islander deaths were ... Contents >> Deaths of Aboriginal and Torres Strait Islander Persons >> Diseases of the Digestive System (K00-K93) ...
*  3303.0 - Causes of Death, Australia, 2010
Causes of death is presented in the publication in a number of different ways including: by underlying cause, leading causes ... Revised 2009 and final 2008 Causes of Death data are also presented in this publication by underlying cause of death. In ... and multiple causes. Data is also presented for deaths of Aboriginal and Torres Strait Islander persons, and for suicide deaths ... sex and cause of death classified to the World Health Organisation's International Classification of Diseases (ICD) will
http://abs.gov.au/ausstats/abs@.nsf/Previousproducts/3303.0Main Features99992010?opendocument&tabname=Summary&prodno=3303.0&issue=2010&num=&view=
*  3303.0 - Causes of Death, Australia, 2013
Data in the Causes of Death collection include demographic items as well as Causes of Death information, which is coded ... The ABS causes of death collection includes all deaths that occurred and were registered in Australia, including deaths of ... Errors in the coding of the causes of a death to ICD-10. The majority of cause of death coding is undertaken through an ... Issues for causes of death data: *The Causes of Death publication contains detailed Explanatory Notes, Technical Notes, ...
*  Comments about 'Russia: Arafat's death not caused by radiation' | Deseret News
We welcome your thoughtful comments about 'Russia: Arafat's death not caused by radiation' ... Russia: Arafat's death not caused by radiation. Published: Dec. 26, 2013 12:00 a.m. Updated: Dec. 26, 2013 12:08 p.m. ...
*  British Teen's Death Caused By Loud Music? Heart Long QT Syndrome - ABC News
"It is infrequent and there is no reason for public alarm, if indeed this is the cause of death in this individual," said Dr. ... In some cases it can be caused by exercise, and in other variants, being in the water seems to cause it. ... "they should do post mortem genetic testing to get a definitive cause of death. This would have implications for family members ... But as shocking as the sudden death of a young person may be, long QT syndrome is not something the average person needs to ...
http://abcnews.go.com/Health/HeartRhythmNews/british-teens-death-caused -loud-music/story?id=9344432&page=2
*  PeaceHealth Laboratories New Patent Addresses a Leading Cause of Death...
PeaceHealth Laboratories' New Patent Addresses a Leading Cause of Death: Prescription Drug Abuse ... or using drugs of abuse it has the potential to significantly reduce accidental deaths. (1) ...
*  Programmed cell death assays for plants
... Cadair Home → Gwyddorau Biolegol, Amgylcheddol a Gwledig / Biological, Environmental Rural Sciences → IBERS Research papers → View Item. JavaScript is disabled for your browser. Programmed cell death assays for plants. ; Coimbra, Silvia ; Fath, Angelika ; Sottomayor, Mariana ; Thomas, Howard. Jones, A M, Coimbra, S, Fath, A, Sottomayor, M Thomas, H 2001, ' Programmed cell death assays for plants '. in L M Schwartz J D Ashwell eds, Apoptosis : Cell Death. Programmed cell death PCD is a critical part of normal development at all stages of the plant life cycle. This chapter discusses protocols for PCD assays. DNA degradation is an important diagnostic factor in programmed cell death, and cleavage of DNA in internucleosomal fragments of 180 bp is considered a hallmark of apoptosis. The ability to isolate undegraded high molecular weight DNA from viable tissue is a requirement for studying PCD-induced DNA degradation because it ensures that any DNA degradation observed is ...
*  Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus
... John C. Here we show, in a comprehensive analysis of the global host response induced by the 1918 influenza virus, that mice infected with the reconstructed 1918 influenza virus displayed an increased and accelerated activation of host immune response genes associated with severe pulmonary pathology. We found that mice infected with a virus containing all eight genes from the pandemic virus showed marked activation of pro-inflammatory and cell-death pathways by 24 h after infection that remained unabated until death on day 5. To understand why 1918 influenza virus showed extreme virulence in mice, we used gene expression analysis to provide a global view of the host response in lungs of infected mice. This analysis revealed a significant increase in the expression of genes associated with these immune cell populations in lungs of mice infected with r1918. Figure 2 Increased and earlier expression of genes associated with the activation of key immune cells in mouse lung infected with r1918 ...
*  Cell death
This may be the result of the natural process of old cells dying and being replaced by new ones, or may result from such factors as disease, localized injury, or the death of the organism of which the cells are part. Image:Signal transduction pathways.svg Apoptosis or Type I cell-death, and Autophagy or Type II cell-death are both forms of programmed cell death, while necrosis is a non-physiological process that occurs as a result of infection or injury. 3 Necrosis is cell death caused by external factors such as trauma or infection, and occurs in several different forms. Recently a form of programmed necrosis, called necroptosis, has been recognized as an alternate form of programmed cell death. Autophagy is ' cytoplasm ic', characterized by the formation of large vacuoles that eat away organelles in a specific sequence prior to the destruction of the nucleus. 5 Apoptosis is the process of programmed cell death PCD that may occur in multicellular organisms. ...
*  BNIP3 Upregulation and EndoG Translocation in Delayed Neuronal Death in Stroke and in Hypoxia (PDF D
BNIP3 plays a role in delayed neuronal death in hypoxia and stroke and EndoG is a mediator of the BNIP3-activated neuronal death pathway. stroke S second round of neuronal injury that occurs hours to days after brain ischemia, called delayed neuronal death, in the neighboring areas.2Evidence suggests that the delayed cell death occurs primarily through an apoptosis mechanism.3The caspase family of cysteine proteases plays an indispensable role in the signal transduction and execution of apoptosis.4 However, a growing number of studies supports that a large proportion of the delayed neuronal death in stroke is mediated by caspase-independent pathways.5–7 BNIP3 is a member of a unique family of death-inducing mitochondrial proteins.8Normally, BNIP3 is not expressed in neurons.9,10Expression of BNIP3 is increased under prolonged hypoxic conditions primarily by the transcriptional factor hyp- oxia inducible factor 111and causes cell death in a variety of ...
*  Phys.org - cell death
... Home cell death. News tagged with cell death. 1 week. 1 month. 1 week. 1 month. 1 week. 1 month. cancer cells · cells · protein · brain cells · tumor cells. Microbiologists identify two molecules that kill lymphoma cells in mice. Nov 06, 2011 in Cell & Microbiology. Lights out: A protein may switch off cancer cells. PhysOrg.com -- A protein acting as a switch to activate the cell death process may prove to be an effective targeted treatment for killing cancer cells. Jan 28, 2010 in Cancer. Gelatin nanoparticles could deliver drugs to the brain. Stroke victims could have more time to seek treatment that could reduce harmful effects on the brain, thanks to tiny blobs of gelatin that could deliver the medication to the brain noninvasively. Dec 24, 2014 in Bio & Medicine. Researchers use magnets to cause programmed cancer cell deaths. Phys.org —A team of researchers in South Korea has developed a method to cause cell death in both living fish and lab bowel cancer cells in ...
http://phys.org/tags/cell death/sort/popular/all/
*  Medical Xpress - programmed cell death
... Home programmed cell death. News tagged with programmed cell death. sort by:. Date. 6 hours. 12 hours. 1 day. 3 days. all. Rank. Last day. 1 week. 1 month. all. LiveRank. Last day. 1 week. 1 month. all. Popular. Last day. 1 week. 1 month. all. Related topics: cells · proceedings of the national academy of sciences · cancer cells · protein · cell death. Cancer. Starving cancer cells of sugar could be the key to future treatment. All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. ... Sep 28, 2015 196 0. Cancer. Drug combination improves progression-free survival in melanoma patients. Patients with advanced melanoma skin cancer survive for longer without their disease progressing if they have been treated with a combination of two drugs, nivolumab and ipilimumab, than with either of these drugs alone. ... Sep 28, ...
http://medicalxpress.com/tags/programmed cell death/
*  Guy Salvesen
1999 Caspase mechanisms Guy S Salvesen Program on Apoptosis and Cell Death, Burnham Institute for Medical Research, 10901 N Torrey Pines Road, La Jolla, CA 92037, USA Adv Exp Med Biol 615:13-23. Research Grants INHIBITION OF PROTEASES BY IAPS Guy Salvesen; Fiscal Year: 2001 Apoptosis: Basic Mechanisms and Disease Relevance Guy Salvesen; Fiscal Year: 2003 PROTEASES IN NEURONAL CELL DEATH Guy Salvesen; Fiscal Year: 2003 PROTEINASE INHIBITORY MECHANISMS OF SERPINS Guy Salvesen; Fiscal Year: 2003 PROTEASES IN NEURONAL CELL DEATH Guy Salvesen; Fiscal Year: 2004 ASPIC, a novel MS technology, applied to degradomics Guy Salvesen; Fiscal Year: 2004 PROTEASES IN NEURONAL CELL DEATH Guy Salvesen; Fiscal Year: 2005 ASPIC, a novel MS technology, applied to degradomics Guy Salvesen; Fiscal Year: 2005 PROTEASES IN NEURONAL CELL DEATH Guy Salvesen; Fiscal Year: 2006 PROTEASES IN NEURONAL CELL DEATH Guy Salvesen; Fiscal Year: 2007. Caspase mechanisms Guy S Salvesen Program on ...
*  Phys.org - cell death
... Home cell death. News tagged with cell death. 1 week. 1 week. 1 week. cancer cells · cells · protein · brain cells · tumor cells. Protein-based sensor could detect viral infection or kill cancer cells. MIT biological engineers have developed a modular system of proteins that can detect a particular DNA sequence in a cell and then trigger a specific response, such as cell death. Sep 21, 2015 in Cell & Microbiology. Scientists identify protein at death's door of cells. A protein embedded in the surface of mitochondria - the energy-producing batteries of living cells - opens the door to cell death, causing cells to experience severe power failures, according to new work by researchers at ... Sep 17, 2015 in Cell & Microbiology. Researchers find mistargeted mitochondrial proteins set off a proteostatic response in cytosol. Phys.org —A team of researchers with members from several research centers in Poland and Germany has found that certain mitochondrial proteins can set ...
http://phys.org/tags/cell death/
*  Supernatural - Death Gods and Death Note Rules - Page 2 - AnimeSuki Forum
2008-12-14, 10:25 Link # 21. Join Date: Dec 2008. How to use it I --The human whose name is written in this note shall die. --Even the original owners of the DEATH NOTE, gods of death, do not know much about the note. --If you have traded the eye power of a god of death, you will lose the eye power as well as the memory of the DEATH NOTE, once you lose its ownership. --An individual with the eye power of a god of death can fell the name and life span of other humans by looking at that person's face. But, it is not really necessary for the individual to view the life span of him/herself nor other DEATH NOTE owners. How to use it XX --In order to see the names and life spans of humans by using the eye power of the god of death, the owner must look at more than half of that person's face. --If you write, die of disease for the cause of death, but only write a specific time of death without the actual name of disease, the human will die from an ...
cell death society date correction dec cell death society date correction dec richard a lockshin lockshin at mindspring com mon nov est previous message postdoctoral positions transcriptional regulation and hematopoiesis next message new files online at project inform messages sorted by cell death society date correction dec cell death soc meeting dr joseph doyle rockefeller university characterization of new genes in the regressing rat prostate dr wen chieh liao radiation oncology memorial sloan kettering at inhibits dna damage induced apoptosis via ceramide synthase available on website see note about dec absolute abstract deadline for keystone meeting report on july international meeting new arrangements for combined membership cdd subscription available until end online full articles for cdd follow hyperlink pm pizza pm talks and discussion rockefeller university york ave weiss research bldg room free parking after pm at th st and york ave please car pool as parking space is ...
*  cell Death ELISA
... felix rockmann at compuserve com wed jan est previous message sense antisense genuine confusion next message cell death elisa messages sorted by hi to everybody i got this email adress from a german forum on compuserve so i hope that i got ot right i have a question does anybody has experience with the cell death detection elisa of boehringer manheim i am working on my doktors degree and i have to use this kit for apoptosis analysis so i would like to get any comments remarks tips and tricks thanks a lot in advance felix munich germany p s how do i get in your newsgroup i am a freshman in the internet so i need a veryx easy way to get in contact previous message sense antisense genuine confusion next message cell death elisa messages sorted by more information about the methods mailing list
*  programmed cell death | SciVee
programmed cell death scivee login username password register forget your password click here follow scivee login upload home journals conferences education search all content all content journals conferences education communities sciveecasts videos all content journals conferences education communities sciveecasts videos please enter at least characters apoptosis by xiaodong wang june part introduction to apoptosis submitted by video collector apoptosis a form of programmed cell death that plays important roles during animal development immune response elimination of damaged cells and maintenance of tissue homeostasis apoptosis is executed by intracellular proteases named caspases that are activated during the onset of apoptosis by extrinsic and intrinsic pathways the intrinsic pathway is triggered by the release of proteins such as cytochrome c from mitochondria to cytosol and the extrinsic pathway is activated by the solutions products journals conferences teachyou education brochure ...
*  Death Race 2000 Timeline
Death Race 2000 895 Views Share: Follow. Death Race 2000 has no followers yet. Death Race 2000 1975 trailer Jun 15, 2013 3:57 AM Death Race 2000 1975 DVDRip SiRiUs sHaRe Part 5 Apr 22, 2013 12:14 AM Uploaded with Free Video Converter from Freemake http://www.freemake.com/free video converter/ Death Race 2000 1975 DVDRip SiRiUs sHaRe Part 4 Apr 21, 2013 11:59 PM Uploaded with Free Video Converter from Freemake http://www.freemake.com/free video converter/ Death Race 2000 1975 DVDRip SiRiUs sHaRe Part 2 Apr 21, 2013 11:29 PM Uploaded with Free Video Converter from Freemake http://www.freemake.com/free video converter/ Death Race 2000 1975 DVDRip SiRiUs sHaRe Part 1 Apr 21, 2013 11:15 PM Uploaded with Free Video Converter from Freemake http://www.freemake.com/free video converter/ The Sci-Fi Film School #32 - Death Race 2000 Apr 18, 2013 8:54 PM On this episode of The Sci-Fi Film School we review the 1975 Roger Corman movie Death Race 2000. ...
*  “Dead Cells Talking”: The Silent Form of Cell Death Is Not so Quiet : Figure 1
x c dead cells talking x d the silent form of cell death is not so quiet figure figure apoptotic stimuli activate caspases triggering the proteolysis of a large number of intracellular substrates the cleavage of many of these including icad and lamins is necessary for the morphological and biochemical changes of apoptosis other substrates have as yet undefined roles while the cleavage of ipla is critical for the paracrine signalling that induces compensatory proliferation cleavage of ipla increases its activity so raising the levels of pge and lpc pge in turn activates ep g protein coupled receptors on stem or progenitor cells intracellular signalling downstream of ep activates x b catenin and leads to cell proliferation lpc and atp may indirectly induce compensatory proliferation through the recruitment of macrophages
*  Necrobiology
... comprises the life processes associated with morphological biochemical and molecular changes which predispose precede and accompany cell death as well as the consequences and tissue response to cell death the word is derived from the greek νεκρό meaning death βìο meaning life and λόγος meaning the study of see also apoptosis necrosis programmed cell death references external links category cellular processes category medical aspects of death category programmed cell death
*  Dignified death
... is a somewhat elusive concept often related to suicide one factor that has been cited as a core component of dignified death is maintaining a sense of control another view is that a truly dignified death is an extension of a dignified life there is some concern that assisted suicide does not guarantee a dignified death since some patients may experience complications such as nausea and vomiting there is some concern that age discrimination denies the elderly a dignified death references category death
*  Immune Therapy and β-Cell Death in Type 1 Diabetes
immune therapy and β cell death in type diabetes
http://diabetes.diabetesjournals.org/content/early/2013/02/14/db12-1207.full.pdf html
*  Starved to death
... redirect starvation
*  Category:Deaths by poisoning
category deaths by poisoning category deaths by poisoning category poisons poisoning
*  Category:Deaths by blood poisoning
category deaths by blood poisoning category deaths by blood poisoning
*  Death by poisoning
... redirect poison
*  What Commonly Used Design Detail Should Die A Very Quick Death?
What Commonly Used Design Detail Should Die A Very Quick Death.
*  Aggregate Hospitolization and Death Reporting, 2008-09
aggregate hospitolization and death reporting centers for disease control and prevention
*  Package: Data Elements
... Hide Navigation. Contact Us. Help. Main Menu. Data Field Notes. . Data Field Notes. Navigation:. Advanced Search All Items Index A-Z. Data Model: Attributes Classes Diagrams Data Dictionary: NHS Business Definitions Supporting Information Data Elements A Act Ad Ag An. Ap As. B Bay Be Bl Bo. Br. C Care CDS Ce Cl. Co Cons Cou Cy. D Dea Del Dia Diag. Dial Disa Do Dr. E Eme Emp En Ep. Ex. F Fo. G Gl. H He Honos Hor Hu. I Imp In Inv. J. K. L Le Li. M Mat Me Men MHMD. Mo. N Ne NHS No Nu. O Oc Org Ori Ou. Ov Ox. Pe Pers Ph Pl. Po Pot Pres Pret. Pri Proc Prod. Q. R Ref Reg Ren Rep. S Sc Se Set Site. Sk So St Star. Stat Sto Str Su. Sur Sy. T Th To TP Tr. Tu. U Un Ur. V. W War We Wo. Y. Dea DEATH CAUSE CODE EUROPEAN DIALYSIS AND TRANSPLANT ASSOCIATION CLASSIFICATION DEATH CAUSE CODE TRANSPLANT DONOR DEATH CAUSE COMMENT DEATH CAUSE ICD CODE DEATH CAUSE ICD CODE CONDITION DEATH CAUSE ICD CODE CONTRIBUTING CONDITION DEATH CAUSE ICD CODE DUE TO CONDITION DEATH ...
*  ICD-9 SEER Cause-specific Death for Sequence 01 (1973-2007 Data) - SEER Recodes
ICD-9 SEER Cause-specific Death for Sequence 01 1973-2007 Data - SEER Recodes. at the National Institutes of Health. Cancer Statistics. Cancer Statistics Review An annual compilation of the most recent cancer statistics. Defining Cancer Statistics Incidence. Statistics by Race/Ethnicity. Fast Stats Build tables and graphs of cancer statistics by: Cancer Site. Other Tools State Cancer Profiles Maps and graphs showing cancer trends at the national, state, and county level. For Researchers Datasets and Software Datasets SEER Data. Standard Population Data. Mortality Data. Population Data. More Data Software. Statistical Software SEER*Stat. SEER*Prep. Documentation Recodes Behavior Recode for Analysis. Cause of Death Recode. Incidence Site Recode Variables. Other Documentation Recodes. For Cancer Registrars Coding Rules, Training and Support Reporting Guidelines Coding and Staging Manuals. ICD-O-3 Coding Materials. Data Documentation Variable Recodes. About SEER Our Registries and Research Overview ...
*  ICD-10 SEER Cause-specific Death for Sequence 01 - SEER Recodes
... at the National Institutes of Health. Cancer Statistics. Defining Cancer Statistics Incidence. Fast Stats Build tables and graphs of cancer statistics by: Cancer Site. Other Tools State Cancer Profiles Maps and graphs showing cancer trends at the national, state, and county level. For Researchers Datasets and Software Datasets SEER Data. Standard Population Data. Population Data. More Data Software. Statistical Software SEER*Stat. SEER*Prep. Documentation Recodes Behavior Recode for Analysis. Cause of Death Recode. Incidence Site Recode Variables. Other Documentation Recodes. For Cancer Registrars Coding Rules, Training and Support Reporting Guidelines Coding and Staging Manuals. Data Documentation Variable Recodes. About SEER Our Registries and Research Overview SEER is an authoritative source of information on cancer incidence and survival in the United States. SEER currently collects and publishes cancer incidence and survival data from population-based cancer registries covering approximately ...
*  Cause of death
International definition of 'cause of death' Underlying cause of death. Current state of collection of causes of death Reporting causes of death Medical Certification - International form of medical certificate of cause of death World Health Organization - format agreed 1990. Data sources for causes of death Civil registration and vital statistics systems. Sample and local demographic surveillance systems. Hospital data on cause-specific mortality. China and India, the most populated countries in the world, do not have truly functional civil registration systems; instead, both use sample registration to generate representative mortality statistics. Currently, 34 countries, which make up 15 percent of the world population, produce high-quality cause of death statistics. 85 other countries, about 65 percent of the world population, produce lower quality cause of death statistics. Medical Certification - International form of medical certificate of cause ...
*  The development and external validation of a model to predict one year all-cause mortality following
... liver function tests in primary care patients - Research Database, The University of Dundee. University of Dundee. university home. University Search. Discovery - University of Dundee - Online Publications. Library Learning Centre. Research Outputs. Research Outputs. Journals. The development and external validation of a model to predict one year all-cause mortality following liver function tests in primary care patients. The development and external validation of a model to predict one year all-cause mortality following liver function tests in primary care patients. Research output : Contribution to journal › Article. Authors. P T Donnan. Division of Population Health Sciences. Quality, Safety Informatics Research Group. Journal. Value in Health. Journal publication date 2011. 10.1016/j.jval.2011.08.877. By the same authors. Construction of a linked health and social care database resource: lessons on process, content and culture., Donnan, P. 1 Sep 2015 In : Informatics for Health and Social Care. ...
*  Death by natural causes
... natural death horse the band s album a natural death a death by natural causes as recorded by coroner s and on death certificate s and associated documents is one that is primarily attributed to an illness or an internal malfunction of the body not directly influenced by external forces for example a person dying from complications from influenza an infection or a heart attack an internal body malfunction or sudden heart failure would be listed as having died from natural causes old age is not a scientifically recognized cause of death there is always a more direct cause although it may be unknown in certain cases and could be one of a number of aging associated diseases by contrast death caused by active intervention is called unnatural death the unnatural causes are usually given as accident implying no unreasonable voluntary risk misadventure accident following a willful and dangerous risk suicide or homicide in some settings other categories may be ...
*  UPDATE: Student found in car died of natural causes
... Weather 48. Local. Nation Now. Traffic. Sports. Features. Video. Photos. Store. Weather. Local. Nation Now. Traffic. Sports. Features. Video. Photos. Store. User. Sign in with Facebook Sign in with Google Sign In FAQ. You are logged in as. Log out Sign In FAQ. Get the news. Log In or Subscribe to skip. Sign in with Facebook Sign in with Google Sign in FAQ. Share This Story. Let friends in your social network know what you are reading about. Facebook Email. Twitter. Google+. LinkedIn. Pinterest. UPDATE: Student found in car died of natural causes. UPDATE: Student found in car died of natural causes. Post to Facebook. UPDATE: Student found in car died of natural causes UPDATE: Student found in car died of natural causes Check out this story on WZZM13.com: http://www.wzzm13.com/story/local/2013/09/23/1611232/. A link has been sent to your friend's email address. Posted. A link has been posted to your Facebook feed. Join the Conversation. To find out more about Facebook commenting ...
*  Diabetes mellitus, fasting glucose, and risk of cause-specific death. | Beta Cells in Diabetes
Diabetes mellitus, fasting glucose, and risk of cause-specific death. Beta Cells in Diabetes Betacell. A resource for physicians established by the Endocrine Society Text Size:. Email Newsletter Podcast. Home βCell Science Case Studies Expert Blog Resources CME About Us. Mission Statement Content Editorial Board Editorial Contributors For Patients Information and Policies Sign Up For Email Updates Contact Us Podcasts. Resource Resource RSS. General Reviews Pathophysiology Interventions Additional Resources View the Full Resource List. Search Resources. Category:. All Categories -------------------- General Reviews Pathophysiology Interventions Additional Resources. Format: 2015-10-04. Latest:. Format: 2015-10-04. Participate Win These Two Educational Resources Congratulations to our latest winner: Julio Sifuentes. Get involved in any activity of the Beta Cells in Diabetes website, and we'll enter you in a monthly drawing for this pair of educational resources from The Endocrine Society: - Endocrine ...
*  Heat Waves and Cause-specific Mortality at all Ages : Epidemiology
... Advertisement. Enter your Email address:. Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining your privacy and will not share your personal information without your express consent. For more information, please refer to our Privacy Policy. Epidemiology Wolters Kluwer Health Logo. Subscribe. Search Jobs. Saved Searches. Recent Searches. You currently have no recent searches. Login. Register. Activate Subscription. eTOC. Help. All Issues Current Issue Issue Displayed. Advanced Search. Home Currently selected. Current Issue. Previous Issues. Published Ahead-of-Print. Collections. Podcasts. Videos. For Authors. Information for Authors. Language Editing Services. Journal Info. About the Journal. Mission Statement. Editorial Board. Affiliated Society. Advertising. Open Access. Subscription Services. Reprints. Rights and Permissions. Mobile. New Features. iPad App. Home. November 2011 - Volume 22 - Issue 6. Heat Waves and Cause-specific Mortality at all Ages. ...
*  CDC: Lifestyle Changes Can Reduce Death From Top 5 Causes
... Espa ol. Asian Pacific Languages. Sign Up for Email. Sign In. Register. Donate. How can we help you. Search. Live Chat. 800-227-2345. Home. Learn About Cancer. Stay Healthy. Find Support & Treatment. Explore Research. Get Involved. Find Local ACS. Learn About Cancer. News and Features. News. CDC: Lifestyle Changes Can Reduce Death From Top 5 Causes. Share this Page. Close. Push escape to close share window. Print. Share. Save. Saved this Article. Close. Push escape to close saved articles window. My Saved Articles. My ACS. + - Text Size. News. Filed under: Cancer Risks/Causes, Diet/Exercise/Weight, Prevention/Early Detection, Smoking/Tobacco, Sun Safety/Tanning. CDC: Lifestyle Changes Can Reduce Death From Top 5 Causes. Article date: June 24, 2014. By Stacy Simon. Lifestyle changes like avoiding tobacco, increasing physical activity, and eating healthier could significantly reduce deaths in the United States, according to a recent report from the Centers for Disease Control and ...
*  U.S. must improve baby death statistics - Longmont Times-Call
... Hot Topics: Seeking VW refund. Moose killed. Diagonal crash. TC Line. Longs Peak death. Johnnie St. Vrain. News tips. Editorials U.S. must improve baby death statistics. Posted: 05/16/2013 01:00:00 AM MDT Updated: 05/16/2013 06:39:38 AM MDT. In a nation that is quick to tout its health care system as the best in the world, troubling signs have emerged that should give pause to those who craft public policy. While the United States leads the world in research into the causes of diseases, and the top doctors and top hospitals continue push the boundaries into care that only decades ago would have been described as miraculous, a large number of citizens are not seeing the benefits in their lives or, most unfortunately, the lives of their children. Last week, the advocacy group Save the Children released a report on the survival rates for children on the day of their birth, and it noted that a baby's first day of life is its most dangerous, regardless of whether he or she is born in a wealthy ...
*  Natural Causes | OC Weekly
Natural Causes. OC Weekly. OC Events Top Picks Submit an Event Things To Do Newsletter Get Mobile Entertainment Ads Tickets Dating. OC Movies Film Blog Film Festivals Movie Trailers 2014 Film Poll Podcast Film & TV Newsletter Showtimes Get Mobile Free Stuff Dating. Natural Causes The naked life and veiled death of a Playboy Playmate A A A. Playboy's Nude Playmates. Bridges was dead when the magazine was published. Weeks later, the July 2002 issue of Playboy magazine reported, The coroner has concluded that her death was due to natural causes. Natural causesThere was nothing natural about Bridges' death. A drug overdose in a room where no drugs were found, in a house she didn't live in. Then again, wasn't Bridges part of the famous Playboy promise that Once a Playmate, always a Playmate. One big, naked sorority stretching back to the first playmate, Marilyn Monroe, who died under mysterious circumstances.So maybe Elisa Bridges wasn't forgotten. Nahem, 58, told police Bridges often stayed ...
*  Thousands in U.S. die unnecessarily | HeraldNet.com - Nation & World
die unnecessarily. HeraldNet.com - Nation & World. News. Jobs. Local news. Calendar. Local news. Everett. Calendar. Calendar. If all Americans had equal access to the best preventive care currently available somewhere in the country, roughly 20 percent to 40 percent of premature deaths from the five leading causes of death could be avoided, CDC researchers calculated. Every year, about 895,000 Americans younger than 80 die as a result of heart disease, cancer, chronic lower respiratory diseases, stroke and accidents, government data show. To figure out how many people fit into that category, the researchers calculated the mortality rates for each of those five causes of death in each of the 50 states plus the District of Columbia. Next, the researchers applied those ideal mortality rates to each state and calculated how many people younger than 80 would have died of heart disease, cancer, respiratory diseases, stroke and accidents. The difference between the ideal and actual mortality ...
*  WHO | The top 10 causes of death
WHO. The top 10 causes of death. Skip to main content. Access. Home Alt+0. Navigation Alt+1. Content Alt+2. Search. Search the WHO .int site. Submit. Advanced search. Navigation. Home. Health topics. Data. Media centre. Publications. Countries. Programmes. Governance. About WHO. Language. عربي. 中文. English. Français. Русский. Español. RSS Feed. Youtube. Twitter. Facebook. Google +. iTunes. Play Store. Media centre. Menu. Media centre. News. News releases. Previous years. Statements. Previous years. Notes for the media. Previous years. Events. Official WHO health days. Meetings and consultations. 2014. Fact sheets. Features. Commentaries. Multimedia. Contacts. The top 10 causes of death. Why do we need to know the reasons people die. Measuring how many people die each year and why they died is one of the most important means – along with gauging how diseases and injuries are affecting people – for assessing the effectiveness of a country’s health system. Cause-of-death statistics help ...
*  Question on Death Note inside cover! [Archive] - Cosplay.com
Question on Death Note inside cover. - Cosplay.com. Cosplay.com. Cosplay by Series/Genre. Anime/Manga. Death Note Question on Death Note inside cover. View Full Version : Question on Death Note inside cover. arieuia 03-31-2008, 11:52 PM. I'm planning on making two death notes for a group cosplay both Light's and Misa's, but I was wondering about the inside cover. From the anime, the inside cover seems to be this http://i4.photobucket.com/albums/y147/biscea/deathnote-instructions.png. But from a scan of my manga, it's this http://i4.photobucket.com/albums/y147/biscea/alternativedeathnote.jpg. benihime 03-31-2008, 11:57 PM. it says in there that light wrote it down in japanese because english gives him a headache or something like that. so no misa's death note would not be the same. and you won't find a picture of it because there wasn't a picture of it. that inside cover is just for artful purposes for the dvd. arieuia 04-01-2008, 12:01 AM. I'd worked it ...
*  Rebel Without a Curse - Everything2.com
Actress Titles: 66 Age at time of death : 43 Cause of death: Drowning. Best actress in a Supporting Role: Rebel Without a Cause 1955. Immortalised in songs: Was mentioned in the movie/play "Grease" during the song "Look at Me, I'm Sandra Dee." The lyric goes: "Oh, no, no, Sal Mineo, I would never stoop so low." Academy Award Trivia: He was nominated for Best Supporting Actor for his performance in Rebel Without a Cause and again for his role as Dov Landau in Exodus 1960. Academy Award Trivia: None. Actor Titles: 352 + Age at time of death: 89 Cause of death: Natural causes. Academy Award Trivia: None. He died in Palm Springs, California, Actor titles: 134 Age at time of death: 55 Cause of death: Pneumonia Academy Award Trivia: None, but he had one Emmy nomination for Perry Mason 1959. Actor titles: 203 Self Talk Shows/Documentaries/Host:213 titles Age at time of death: 74 Cause of death: Prostate cancer Academy Award Trivia: Nominated for Best Actor in ...
http://everything2.com/title/Rebel Without a Curse?author_id=2018637
*  Running of any length or speed reduces risk of death
... Coast Life. Coast Life. Running of any length or speed reduces risk of death. Whether they run 30 minutes a week or two hours a week, runners have a 30% lower risk of death than non-runners. Running of any length or speed reduces risk of death Whether they run 30 minutes a week or two hours a week, runners have a 30% lower risk of death than non-runners. Running of any length or speed reduces risk of death. A new study says running, no matter how many long or fast, can help lower your risk of early death. Whether you run 30 minutes a week or two hours a week, your risk of early death will be the same — better than if you don't run. Researchers found that running, no matter the duration or speed, will reduce mortality risk by about 30% compared with non-runners. Contrary to the 150 minutes of moderate exercise or the 75 minutes of vigorous exercise per week recommended by the U.S. Runners had a 30% lower risk of death overall and a 45% ...
*  Health Objectives for the Nation Deaths Resulting from Residential Fires -- United States, 1991
During 1991, residential fires were the second leading cause of injury deaths after motor-vehicle-related injuries among children aged 1-9 years 1 and the sixth leading cause of such deaths among persons aged greater than or equal to 65 years. NFIRS estimates of deaths associated with residential fires for children aged less than 5 years were based on 279 deaths, and for adults aged greater than 70 years, 368 deaths. These deaths included 711 19% among children aged less than 5 years and 898 24% among persons aged greater than or equal to 70 years. Based on NFIRS data for January-December 1990, the causes of the fires were known for 522 72% deaths of children aged less than 5 years; the three leading causes were 1 children playing with fire-ignition sources e.g., matches 37%, 2 faulty or misused heating devices 19%, and 3 faulty or misused electrical distribution sources * 11%. For persons aged greater than 70 years, the causes of fires were known for 247 67% ...
*  Death: At Death's Door - Everything2.com
... Near Matches Ignore Exact. Everything 2. Death: At Death's Door. thing. by. ClockworkGrue. Wed Aug 20 2003 at 1:18:56. "Girls can be anything they want to be. Even the anthropomorphic personifications of aspects of the universe!" Death: At Death's Door is an American Japanese-style comic by Jill Thompson of Li'l Endless fame following the adventures of Neil Gaiman 's proto- perky goth, Death. The story is set in parallel to the Season of Mists ' storyline in Gaiman's The Sandman. Through a series of unfortunate events, Lord Morpheus has found himself in possession of the key to the main gate of Hell following the retirement of that smooth devil, Lucifer Morningstar. Hell's denizens have been released to the four winds, demons and damned mortals alike. With a whole bunch of dead mortals suddenly without their afterlife of choice that's how it works in the Sandman universe, Death finds herself in quite a kerfluffle : as was shown in Chapter 4 of Season of Mists, ...
http://everything2.com/title/Death%3A At Death%27s Door
*  Category:Infectious disease deaths in the United Kingdom
category infectious disease deaths in the united kingdom category infectious disease deaths in the united kingdom united kingdom category disease related deaths in the united kingdom
*  Category:Infectious disease deaths in Wisconsin
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*  Category:Infectious disease deaths in the United States
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*  Category:Neurological disease deaths in the United Kingdom
category neurological disease deaths in the united kingdom category neurological disease deaths in the united kingdom united kingdom category disease related deaths in the united kingdom
*  Category:Neurological disease deaths in the United States
category neurological disease deaths in the united states category neurological disease deaths in the united states united states category disease related deaths in the united states
*  Category:Infectious disease deaths in California
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*  Category:Infectious disease deaths in Iowa
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*  Category:Infectious disease deaths in Jamaica
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*  Category:Infectious disease deaths in Maine
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*  Category:Infectious disease deaths in Utah
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*  Category:Effects of external causes
category effects of external causes category effects of external causes category poisoning and certain other consequences of external causes
*  Underlying cause of death
... redirect mortality medical data system
*  Category:Cancer deaths in Wisconsin
category cancer deaths in wisconsin category cancer deaths in wisconsin wisconsin category disease related deaths in wisconsin
*  Category:Cancer deaths in the United States
category cancer deaths in the united states category cancer deaths in the united states united states category disease related deaths in the united states
*  Category:Cancer deaths in California
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*  Category:Cancer deaths in France
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*  Category:Cancer deaths in Myanmar
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*  Category:Cancer deaths in Iowa
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*  Category:Cancer deaths in Maine
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*  Category:Cancer deaths in Utah
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*  Category:Disease-related deaths in Wisconsin
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*  Category:Disease-related deaths in the United States
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*  Category:Disease-related deaths in California
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*  Category:Disease-related deaths in France
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*  Category:Disease-related deaths in Myanmar
category disease related deaths in myanmar category disease related deaths in myanmar ifeq category myanmar category deaths in myanmar
*  Category:Disease-related deaths in Cambodia
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*  Category:Disease-related deaths in Iowa
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*  Category:Disease-related deaths in Maine
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*  Category:Disease-related deaths in Utah
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*  Category:MRSA deaths in the United States
category mrsa deaths in the united states category mrsa deaths in the united states category infectious disease deaths in the united states united states
*  Category:Disease-related deaths in the United States by state or territory
category disease related deaths in the united states by state or territory category disease related deaths in the united states by state or territory disease
*  Rate of death
... redirect mortality rate
*  How Many Hours You Should Limit Your Sitting To, To Avoid an Early Death
*  Non-heart-beating donation
... 1 Donors after brain-dead DBD, beating heart cadaver s, however, led to better results as the organs were perfused with oxygenated blood until the point of perfusion and cooling at organ retrieval, and so non-heart beating donors were generally no longer used except in Japan, where brain-death was not legally, until very recently,. Maastricht classification Organs that can be used Procedure for uncontrolled donors Procedure for controlled donors Results of NHBD transplantation Ethical issues Actions prior to consent Dead donor rule Pain and suffering Informed consent DCD and the future References External links. Kidneys can be used from category II donors, and all organs except the heart can potentially be used from category III, IV and V donors. In light of this we can now raise the question of whether patients declared dead by cardiocirculatory criteria are really dead. "The ethics of donation and transplantation: are definitions of death being distorted for organ transplantation. Thus, ...
*  Donation after cardiac death liver transplantation: Another fly in the ointment - Parikh - 2012 - Li
donation after cardiac death liver transplantation another fly in the ointment parikh liver transplantation wiley online library you have free access to this content liver transplantation volume issue article first published online dec abstract full article html enhanced article html references cited by
*  lection: the way some people die
... lection. home authors titles dates links about. the way some people die. 19 december 2010 I was lucky enough, at a big barn-like booksale at a local museum lately, to pick up two big Ross Macdonald omnibuses: Archer in Hollywood 1967 and Archer in Jeopardy 1979. And I immediately suffered the social scorn of carrying around triple-decker pulp volumes when I stopped at the cobbler's shop across Main Street: "What have you got there," the cobbler asked, "Reader's Digest condensed books?" "Omnibuses are often posthumous," says Macdonald in the foreword to Archer in Hollywood ; "it's nice, for me at least, that this one isn't" vii. Macdonald also says in this foreword, of The Way Some People Die 1951, that some consider it his best book. But in now long-posthumous retrospect, of course, some book has to be an author's best. I haven't read enough of Ross Macdonald to confirm or dispute critical judgments on the relative standing of The Way Some People Die. The Way Some People Die starts like The Big Sleep ...
*  HOW MANY PEOPLE DIE EVERY YEAR TAKING TYLENOL CORRECTLY - How many people die each year from using t
... ylenol :: Answer Me True. Health. Allergies Alternative Medicine Cancer Dental Diabetes Diet Fitness First Aid Heart Diseases Infectious Diseases Injuries Men s Health Mental Health Other - Diseases Other - General Health Care Other - Health Other - Health Beauty Pain Pain Management Respiratory Diseases Skin Conditions STDs Women s Health. Q How many people die every year taking tylenol correctly. How many people die each year from using tylenol. The answer would be to many, gun control is virtually none existent in the USA the NRA ar ... Post to Facebook. Post to Twitter. Level 1 Contributor 1 Answer "Tylenol is safe so long as you...". Tweet. Tylenol is safe so long as you take just one pill at a time and don`t mix it with alcohol. It becomes unsafe when people don`t realize the danger and pop 2 or 3. Was this answer helpful. Comment. Reply. Report. Level 8 Authority 710 Answers, 1 Friend, 5 Followers "It because sometimes the us allows more people to come in from different countries...". That ...
*  Phenoptosis
Recently this has been referred to as “fast phenoptosis” as aging is being explored as “slow phenoptosis.”. Evolutionary significance Examples in nature Examples in humans Proposed mechanisms Other examples References See also. 3 ‘’’Stress-induced, acute, or fast phenoptosis’’’ is the rapid deterioration of an organism induced by a life event such as breeding. As a species this has been advantageous particularly to species that die immediately after spawning. ‘’’Age-induced, soft, or slow phenoptosis’’’ is the slow deterioration and death of an organism due to accumulated stresses over long periods of time. P Skulachev provides that of two hares, one faster and one smarter, the faster hare may have a selective advantage in youth but as aging occurs and muscles deteriorate it is the smarter hare that now has the selective advantage. 6 Amoeba ' Dictyostelium ' – Under stress amoeba form multicellular fruiting bodies. 7 Nematode ' Caenorhabditis elegans ' – Under normal conditions 'Caenorhabditis ...
*  Bush Radio 89.5 fm Newsroom: 19 people die on WCape roads over weekend
bush radio fm newsroom people die on wcape roads over weekend bush radio fm is the mother of community radio in africa based in cape town south africa bush radio exists with the sole purpose to uplift develop and educate the communities it serves to find out more about bush radio go to www bushradio co za where you can also listen on line please share your comments on our news feedback bushradio co za monday december people die on wcape roads over weekend athenkosi mvane december people have died on the western cape roads since thursday western cape traffic chief kenny africa said on thursday people died in when a car and a truck collided on friday people died saturday two people and between sunday night and this morning two more people died africa says most of these accidents occur because of fatigue we would like to urge our motorists when taking long journeys to plan their trips africa said make sure you stop every two hours or km get out of the car and walk around it so you can be fit for the next ...
*  Childless People Die Early, But Adopting Can Save Your Miserable Life
... Follow Jezebel. Following Jezebel. Gawker. Jezebel. Childless People Die Early, But Adopting Can Save Your Miserable Life. 1 Tracie Egan Morrissey Filed to: Breeding. Daily Mail. The Daily Mail has perfected the art of trolling with its incendiary headlines, and today is no different. The article, Childless couples have higher risk of dying prematurely but adopting may reduce chances of an early death, has an equally hilarious accompanying stock photo of a happily smug family, and refers to having children as life-fulfillment that could extend your years. And among possible risks of early death for sad, selfish childless people are risky behaviors like drinking, drugs, depression, psychiatric illness, and physical illness linked to infertility. Yes, Samantha Brick Is Obnoxious, But the Daily Mail Is Trolling Us All. Yes, Samantha Brick Is Obnoxious, But the Daily Mail Is Trolling Us All. Yes, Samantha Brick Is Obnoxious, But the Daily Ma. Read more Read more. First of all, the research was ...
*  New Research: Skinny People Die Young | Charlotte Hilton Andersen
New Research: Skinny People Die Young. Charlotte Hilton Andersen. About Me Writing Archives Contact. 8 Nov 2007. New Research: Skinny People Die Young Posted at 1:32 pm. by. Charlotte, on November 8, 2007. Compared to overweight people, that is. Contradicting what I, and many of you, have come to feel is common sense, this study says that people in the overweight category of the BMI scale live longer, healthier lives than their normal counterparts with people in the underweight and obese categories having the worst outcomes. Okay, so ignore the underweight and obese people for a moment; I think we can all figure out why they might have health problems Kate Moss Chris Farley walk into a bar. Um, OVERWEIGHT people have better health outcomes than NORMAL people!. This is huge. And underreported, according to Gina Kolata, author of Rethinking Thin: The New Science of Weight Loss And the Myths and Realities of Dieting. Despite being done over two years ago, this study is finally being published in the Journal of ...
*  On average how many people die from alcohol poisoning per year in the USA? | Toluna
On average how many people die from alcohol poisoning per year in the USA. Toluna. Share Poll. Poll link. Copy. Embed Widget. Widget width 500 px 350 px 250 px Custom. Copy Preview. Embedded widget preview: Width - px Height - px. Close preview. You are using a non-supported browser Your browser version is not optimised for Toluna, we recommend that you install the latest version Upgrade. EXPLORE. Rewards Center. Polls. Topics. Register CREATE. Sign Up. Sign in. See all users: " ". slygon is using Toluna to create cool content and you can too by signing up now. slygon 67 months ago. On average how many people die from alcohol poisoning per year in the USA. Closed. Infographics. 0% 0 votes. 0% 0 votes. 17 people voted. 317 3 votes. 5,000 8 votes. 5,000. 47%. 500,000 6 votes. 500,000. 35%. See all results. 17 people voted. Embed this poll on your blog. l side:0.0468003. Related polls and topics. Closed. r side:0. Share by email. Cancel Cancel Send. You’re almost there In order to create content on the ...
*  Cap'n Transit Rides Again: When speeding is common, people die
... Cap'n Transit Rides Again. Here are some reasons to get people to shift from cars to transit: Reducing pollution Increasing efficiency Reducing carnage Improving society Access for all. Home Transportation myopia I don't want to take your car A Cancer in our Midst. Tuesday, May 1, 2012. When speeding is common, people die. By now you've heard the tragic headlines. A middle-aged woman accidentally drove her van off the side of the Bronx River Parkway yesterday, killing herself and everyone aboard - her parents, her sister, her daughter and two nieces. You may have also read statements by Robert Sinclair, president of the Automobile Club of New York, that the Parkway "lacks modern transportation engineering features" because it was conceived in 1907 and opened in 1925 as "the first limited access multilane highway in the U.S." He went on to complain about the guardrail: "It is very strange that there is a curb there," Sinclair said. "You don't put curbs on high-speed roadways because they can serve as ...

Necrobiology: Necrobiology comprises the life processes associated with morphological, biochemical, and molecular changes which predispose, precede, and accompany cell death, as well as the consequences and tissue response to cell death. The word is derived from the Greek νεκρό meaning "death", βìο meaning "life", and λόγος meaning "the study of".Non-heart-beating donation: Prior to the introduction of brain death into law in the mid to late 1970s, all organ transplants from cadaveric donors came from non-heart beating donors (NHBDs).Organ transplantation in Japan: Organ transplantation in Japan is regulated by the 1997 Organ Transplant Law which legalized organ procurement from "brain dead" donors. After an early involvement in organ transplantation that was on a par with developments in the rest of the world, attitudes in Japan altered after a transplant by Dr.Caspase 12: Caspase 12 is a protein that belongs to a family of enzymes called caspases which cleave their substrates at C-terminal aspartic acid residues. It is closely related to caspase 1 and other members of the caspase family, known as inflammatory caspases, which process and activate inflammatory cytokines such as interleukin 1 and interleukin 18.Temporal analysis of products: Temporal Analysis of Products (TAP), (TAP-2), (TAP-3) is an experimental technique for studyingQRISK: QRISK2 (the most recent version of QRISK) is a prediction algorithm for cardiovascular disease (CVD) that uses traditional risk factors (age, systolic blood pressure, smoking status and ratio of total serum cholesterol to high-density lipoprotein cholesterol) together with body mass index, ethnicity, measures of deprivation, family history, chronic kidney disease, rheumatoid arthritis, atrial fibrillation, diabetes mellitus, and antihypertensive treatment.Mortality rate: Mortality rate, or death rate, is a measure of the number of deaths (in general, or due to a specific cause) in a particular population, scaled to the size of that population, per unit of time. Mortality rate is typically expressed in units of deaths per 1,000 individuals per year; thus, a mortality rate of 9.Death of Ludwig van Beethoven: The death of Ludwig van Beethoven on 26 March 1827 followed a prolonged illness. It was witnessed by his sister-in-law and by his close friend Anselm Hüttenbrenner, who provided a vivid description of the event.CaspaseCoagulative necrosis: Coagulative necrosis is a type of accidental cell death typically caused by ischemia or infarction. In coagulative necrosis the architecture of dead tissue is preserved for at least a couple of days.Fas receptor: The FAS receptor (FasR), also known as apoptosis antigen 1 (APO-1 or APT), cluster of differentiation 95 (CD95) or tumor necrosis factor receptor superfamily member 6 (TNFRSF6) is a protein that in humans is encoded by the TNFRSF6 gene.Mitochondrion: The mitochondrion (plural mitochondria) is a double membrane-bound organelle found in most eukaryotic cells. The word mitochondrion comes from the Greek , , i.DNA fragmentation: DNA fragmentation is the separation or breaking of DNA strands into pieces. It can be done intentionally by laboratory personnel or by cells, or can occur spontaneously.Autophagy: Autophagy (or autophagocytosis) (from the Greek auto-, "self" and phagein, "to eat"), is the natural, destructive mechanism that disassembles, through a regulated process, unnecessary or dysfunctional cellular components.TUNEL assayDENN1B: DENN1B is a human gene, located on chromosome 1. The gene is hypothesized by Danish scientists Klaus Bønnelykke and Hans Bisgaard to be related to asthma.BH3 interacting-domain death agonist: The BH3 interacting-domain death agonist, or BID, gene is a pro-apoptotic member of the Bcl-2 protein family. Bcl-2 family members share one or more of the four characteristic domains of homology entitled the Bcl-2 homology (BH) domains (named BH1, BH2, BH3 and BH4), and can form hetero- or homodimers.HSD2 neurons: HSD2 neurons are a small group of neurons in the brainstem which are uniquely sensitive to the mineralocorticosteroid hormone aldosterone, through expression of HSD11B2. They are located within the caudal medulla oblongata, in the nucleus of the solitary tract (NTS).List of Parliamentary constituencies in Kent: The ceremonial county of Kent,Bcl-2 familyCancer survival rates: Cancer survival rates vary by the type of cancer, stage at diagnosis, treatment given and many other factors, including country. In general survival rates are improving, although more so for some cancers than others.Mitochondrial ROS: Mitochondrial ROS (mtROS or mROS) are reactive oxygen species (ROS) that are produced by mitochondria. Generation of mitochondrial ROS mainly takes place at the electron transport chain located on the inner mitochondrial membrane during the process of oxidative phosphorylation (OXPHOS).Global Risks Report: The Global Risks Report is an annual study published by the World Economic Forum ahead of the Forum’s Annual Meeting in Davos, Switzerland. Based on the work of the Global Risk Network, the report describes changes occurring in the global risks landscape from year to year and identifies the global risks that could play a critical role in the upcoming year.Age adjustment: In epidemiology and demography, age adjustment, also called age standardization, is a technique used to allow populations to be compared when the age profiles of the populations are quite different.Incidence (epidemiology): Incidence is a measure of the probability of occurrence of a given medical condition in a population within a specified period of time. Although sometimes loosely expressed simply as the number of new cases during some time period, it is better expressed as a proportion or a rate with a denominator.Homicide: Homicide occurs when one human being causes the death of another human being. Homicides can be divided into many overlapping types, including murder, manslaughter, justifiable homicide, killing in war, euthanasia, and execution, depending on the circumstances of the death.Electrocardiography in myocardial infarctionDisease registry: Disease or patient registries are collections of secondary data related to patients with a specific diagnosis, condition, or procedure, and they play an important role in post marketing surveillance of pharmaceuticals. Registries are different from indexes in that they contain more extensive data.Teenage suicide in the United States: Teenage suicide in the United States remains comparatively high in the 15 to 24 age group with 10,000 suicides in this age range in 2004, making it the third leading cause of death for those aged 15 to 24. By comparison, suicide is the 11th leading cause of death for all those age 10 and over, with 33,289 suicides for all US citizens in 2006.Prenatal nutrition: Nutrition and weight management before and during :pregnancy has a profound effect on the development of infants. This is a rather critical time for healthy fetal development as infants rely heavily on maternal stores and nutrient for optimal growth and health outcome later in life.Sisterhood method: The Sisterhood Method is a household survey to estimate maternal deaths, which includes a series of four questions. The Sisterhood Method is one method recommended by the WHO.Bcl-2-associated death promoter: The Bcl-2-associated death promoter (BAD) protein is a pro-apoptotic member of the Bcl-2 gene family which is involved in initiating apoptosis. BAD is a member of the BH3-only familySilent mutation: Silent mutations are mutations in DNA that do not significantly alter the phenotype of the organism in which they occur. Silent mutations can occur in non-coding regions (outside of genes or within introns), or they may occur within exons.National Center for Injury Prevention and Control: The U.S.List of U.S. states by life expectancy: This article presents a list of United States states sorted by their life expectancy at birth and by race/ethnicity in every state where the population of that racial or ethnic group is sufficiently large for robust estimates. The data is taken from the Measure of America's third national human development report, The Measure of America 2013–2014 width="25%" align="center" |Concentration effect: In the study of inhaled anesthetics, the concentration effect is the increase in the rate that the Fa(alveolar concentration)/Fi(inspired concentration) ratio rises as the alveolar concentration of that gas is increased. In simple terms, the higher the concentration of gas administered, the faster the alveolar concentration of that gas approaches the inspired concentration.HeartScore: HeartScore is a cardiovascular disease risk assessment and management tool developed by the European Society of Cardiology, aimed at supporting clinicians in optimising individual cardiovascular risk reduction.Gross pathology: Gross pathology refers to macroscopic manifestations of disease in organs, tissues, and body cavities. The term is commonly used by anatomical pathologists to refer to diagnostically useful findings made during the gross examination portion of surgical specimen processing or an autopsy.Antileukemic drug: Antileukemic drugs, anticancer drugs that are used to treat one or more types of leukemia, include:ConatumumabMatrix model: == Mathematics and physics ==P53: Tumor protein p53, also known as p53, cellular tumor antigen p53 (UniProt name), phosphoprotein p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53), is any isoform of a protein encoded by homologous genes in various organisms, such as TP53 (humans) and Trp53 (mice). This homolog (originally thought to be, and often spoken of as, a single protein) is crucial in multicellular organisms, where it prevents cancer formation, thus, functions as a tumor suppressor.Vital statistics (government records): Vital statistics are statistics on live births, deaths, fetal deaths, marriages and divorces. The most common way of collecting information on these events is through civil registration, an administrative system used by governments to record vital events which occur in their populations (see Box 1).Opioid overdose: .0, -G-CSF factor stem-loop destabilising elementTACI-CRD2 protein domain: In molecular biology, this protein domain, TACI-CRD2 represents the second cysteine-rich protein domain found in the TACI family of proteins. Members of this family are predominantly found in tumour necrosis factor receptor superfamily, member 13b (TACI), and are required for binding to the ligands APRIL and BAFF.Positional asphyxia: Positional asphyxia, also known as postural asphyxia, is a form of asphyxia which occurs when someone's position prevents the person from breathing adequately. Positional asphyxia may be a factor in a significant number of people who die suddenly during restraint by police, prison (corrections) officers or health care staff.RNA transfection: RNA transfection is the process of deliberately introducing RNA into a living cell. RNA can be purified from cells after lysis or synthesized from free nucleotides either chemically, or enzymatically using an RNA polymerase to transcribe a DNA template.Flow cytometry: In biotechnology, flow cytometry is a laser-based, biophysical technology employed in cell counting, cell sorting, biomarker detection and protein engineering, by suspending cells in a stream of fluid and passing them by an electronic detection apparatus. It allows simultaneous multiparametric analysis of the physical and chemical characteristics of up to thousands of particles per second.Red Moss, Greater Manchester: Red Moss is a wetland mossland in Greater Manchester, located south of Horwich and east of Blackrod. (Grid Reference ).Proportional reporting ratio: The proportional reporting ratio (PRR) is a statistic that is used to summarize the extent to which a particular adverse event is reported for individuals taking a specific drug, compared to the frequency at which the same adverse event is reported for patients taking some other drug (or who are taking any drug in a specified class of drugs). The PRR will typically be calculated using a surveillance database in which reports of adverse events from a variety of drugs are recorded.

(1/6129) Avoidable mortality in Europe 1955-1994: a plea for prevention.

OBJECTIVE: To analyse trends of avoidable mortality in Europe, emphasising causes of death amenable to primary prevention through reduction of exposures, secondary prevention through early detection and treatment, and tertiary prevention through improved treatment and medical care. DESIGN: Descriptive study of mortality from avoidable causes for the years 1955 through 1994, for ages 5-64 at time of death. Using the World Health Organisation Mortality Database, five year death rates were standardised to the world population. SETTING: 21 countries of Europe in four regions (northern, central, and southern Europe, Nordic countries). PARTICIPANTS: All causes of deaths for men and women, aged 5-64, at time of death. MAIN RESULTS: Between 1955-59 and 1990-94, the reduction in mortality was somewhat greater for avoidable causes than for all causes: 45.8% v 45.1% (women) and 39.3% v 32.6% among men. Reductions in mortality were greater for causes amenable to improved medical care: 77.9% among women and 76.3% among men. The smallest reduction in mortality was seen in women for causes amenable to secondary prevention (11.0%), and in men for causes amendable to primary prevention including tobacco related conditions (16.6%). From a geographical point of view, there were slight differences in trends between European regions, but overall the patterns were similar. CONCLUSIONS: The greatest reduction of avoidable mortality in Europe from 1955-94 came from causes amenable to improved treatment and medical care for both sexes. Further reductions of avoidable mortality can be achieved through implementation of primary and secondary prevention activities, such as tobacco control, reduction of occupational exposures, and universal access to breast and cervical cancer screening programmes.  (+info)

(2/6129) Comparative total mortality in 25 years in Italian and Greek middle aged rural men.

STUDY OBJECTIVE: Mortality over 25 years has been low in the Italian and very low in the Greek cohorts of the Seven Countries Study; factors responsible for this particularity were studied in detail. PARTICIPANTS AND SETTINGS: 1712 Italian and 1215 Greek men, aged 40-59 years, cohorts of the Seven Countries Study, representing over 95% of the populations in designated rural areas. DESIGN: Entry (1960-61) data included age, systolic blood pressure (SBP), smoking habits, total serum cholesterol, body mass index (BMI), arm circumference, vital capacity (VC), and forced expiratory volume in 3/4 seconds (FEV); the same data were obtained 10 years later. Multivariate Cox analysis was performed with all causes death in 25 years as end point. MAIN RESULTS: Italian men had higher entry levels of SBP, arm circumference, BMI, and VC; Greek men had higher cholesterol levels, smoking habits, and FEV. Mortality of Italian men was higher throughout; at 25 years cumulative mortality was 48.3% and 35.3% respectively. Coronary heart disease and stroke mortality increased fivefold in Italy and 10-fold in Greece between years 10 and 25. The only risk factor with a significantly higher contribution to mortality in Italian men was cholesterol. However, differences in entry SBP (higher in Italy) and FEV (higher in Greece) accounted for, according to the Lee method, 75% of the differential mortality between the two populations. At 10 years increases in SBP, cholesterol, BMI, and decreases in smoking habits, VC, FEV, and arm circumference had occurred (deltas). SBP increased more and FEV and VC decreased more in Italy than in Greece. Deltas, fed stepwise in the original model for the prediction of 10 to 25 years mortality, were significant for SBP, smoking, arm circumference, and VC in Greece, and for SBP and VC in Italy. CONCLUSION: Higher mortality in Italian men is related to stronger positive effects of entry SBP and weaker negative (protective) effects of FEV; in addition 10 year increases in SBP are higher and 10 year decreases in FEV are larger in Italy. Unaccounted factors, however, related to, for example, differences in the diet, may also have contributed to the differential mortality of these two Mediterranean populations.  (+info)

(3/6129) Respiratory symptoms and long-term risk of death from cardiovascular disease, cancer and other causes in Swedish men.

BACKGROUND: Depressed respiratory function and respiratory symptoms are associated with impaired survival. The present study was undertaken to assess the relation between respiratory symptoms and mortality from cardiovascular causes, cancer and all causes in a large population of middle-aged men. METHODS: Prospective population study of 6442 men aged 51-59 at baseline, free of clinical angina pectoris and prior myocardial infarction. RESULTS: During 16 years there were 1804 deaths (786 from cardiovascular disease, 608 from cancer, 103 from pulmonary disease and 307 from any other cause). Men with effort-related breathlessness had increased risk of dying from all of the examined diseases. After adjustment for age, smoking habit and other risk factors, the relative risk (RR) associated with breathlessness of dying from coronary disease was 1.43 (95% CI : 1.16-1.77), from stroke 1.77 (95% CI: 1.07-2.93), from any cardiovascular disease 1.48 (95% CI : 1.24-1.76), cancer 1.36 (95% CI : 1.11-1.67) and from any cause 1.62 (95% CI: 1.44-1.81). An independent effect of breathlessness on cardiovascular death, cancer death and mortality from all causes was found in life-time non-smokers, and also if men with chest pain not considered to be angina were excluded. An independent effect was also found if all deaths during the first half of the follow-up were excluded. Men with cough and phlegm, without breathlessness, also had an elevated risk of dying from cardiovascular disease and cancer, but after adjustment for smoking and other risk factors this was no longer significant. However, a slightly elevated independent risk of dying from any cause was found (RR = 1.18 [95% CI: 1.02-1.36]). CONCLUSION: A positive response to a simple question about effort related breathlessness predicted subsequent mortality from several causes during a follow-up period of 16 years, independently of smoking and other risk factors.  (+info)

(4/6129) Water traffic accidents, drowning and alcohol in Finland, 1969-1995.

OBJECTIVE: To examine age- and sex-specific mortality rates and trends in water traffic accidents (WTA), and their association with alcohol, in Finland. MATERIALS AND METHODS: National mortality and population data from Finland, 1969-1995, are used to analyse rates and trends. The mortality rates are calculated on the basis of population, per 100000 inhabitants in each age group (<1, 1-4, 5-14, 15-24, 25-44, 45-64, > or = 65), and analysed by sex and age. The Poisson regression model and chi2 test for trend (EGRET and StatXact softwares) are used to analyse time trends. RESULTS: From 1969 through 1995 there were 3473 (2.7/100000/year; M:F= 20.4:1) WTA-related deaths among Finns of all ages. In 94.7% of the cases the cause of death was drowning. Alcohol intoxication was a contributing cause of death in 63.0% of the fatalities. During the study period the overall WTA mortality rates declined significantly (-4% per year; P < 0.001). This decline was observed in all age groups except > or = 65 year olds. The overall mortality rates in WTA associated with alcohol intoxication (1987-1995) also declined significantly (-6%; P = 0.01). CONCLUSIONS: In Finland, mortality rates in WTA are exceptionally high. Despite a marked decline in most age groups, the high mortality in WTA nevertheless remains a preventable cause of death. Preventive countermeasures targeted specifically to adult males, to the reduction of alcohol consumption in aquatic settings and to the use of personal safety devices should receive priority.  (+info)

(5/6129) A method for calculating age-weighted death proportions for comparison purposes.

OBJECTIVE: To introduce a method for calculating age-weighted death proportions (wDP) for comparison purposes. MATERIALS AND METHODS: A methodological study using secondary data from the municipality of Sao Paulo, Brazil (1980-1994) was carried out. First, deaths are weighted in terms of years of potential life lost before the age of 100 years. Then, in order to eliminate distortion of comparisons among proportions of years of potential life lost before the age of 100 years (pYPLL-100), the denominator is set to that of a standard age distribution of deaths for all causes. Conventional death proportions (DP), pYPLL-100, and wDP were calculated. RESULTS: Populations in which deaths from a particular cause occur at older ages exhibit lower wDP than those in which deaths occur at younger ages. The sum of all cause-specific wDP equals one only when the test population has exactly the same age distribution of deaths for all causes as that of the standard population. CONCLUSION: Age-weighted death proportions improve the information given by conventional DP, and are strongly recommended for comparison purposes.  (+info)

(6/6129) The meaning and use of the cumulative rate of potential life lost.

BACKGROUND: The 'years of potential life lost' (YPLL) is a public health measure in widespread use. However, the index does not apply to the comparisons between different populations or across different time periods. It also has the limit of being cross-sectional in nature, quantifying current burden but not future impact on society. METHODS: A new years-lost index is proposed-the 'cumulative rate of potential life lost' (CRPLL). It is a simple combination of the 'cumulative rate' (CR) and the YPLL. Vital statistics in Taiwan are used for demonstration and comparison of the new index with existing health-status measures. RESULTS: The CRPLL serves the purpose of between-group comparison. It can also be considered a projection of future impact, under the assumption that the age-specific mortality rates in the current year prevail. For a rare cause of death, it can be interpreted as the expected years (days) of potential life lost during a subject's lifetime. CONCLUSIONS: The CRPLL has several desirable properties, rendering it a promising alternative for quantifying health status.  (+info)

(7/6129) Toxic oil syndrome mortality: the first 13 years.

BACKGROUND: The toxic oil syndrome (TOS) epidemic that occurred in Spain in the spring of 1981 caused approximately 20000 cases of a new illness. Overall mortality and mortality by cause in this cohort through 1994 are described for the first time in this report. METHODS: We contacted, via mail or telephone, almost every living member of the cohort and family members of those who were known to have died in order to identify all deaths from 1 May 1981 through 31 December 1994. Cause of death data were collected from death certificates and underlying causes of death were coded using the International Classification of Diseases, 9th Revision. RESULTS: We identified 1663 deaths between 1 May 1981 and 31 December 1994 among 19 754 TOS cohort members, for a crude mortality rate of 8.4%. Mortality was highest during 1981, with a standardized mortality ratio (SMR) of 4.92 (95% confidence interval [CI]: 4.39-5.50) compared with the Spanish population as a whole. The highest SMR, (20.41, 95% CI: 15.97-25.71) was seen among women aged 20-39 years during the period from 1 May 1981 through 31 December 1982. Women <40 years old, who were affected by TOS , were at greater risk for death in most time periods than their unaffected peers, while older women and men were not. Over the follow-up period, mortality of the cohort was less than expected when compared with mortality of the general Spanish population, or with mortality of the population of the 14 provinces where the epidemic occurred. We also found that, except for deaths attributed to external causes including TOS and deaths due to pulmonary hypertension, all causes of death were decreased in TOS patients compared to the Spanish population. The most frequent underlying causes of death were TOS, 350 (21.1%); circulatory disorders, 536 (32.3%); and malignancies, 310 (18.7%). CONCLUSIONS: We conclude that while on average people affected by toxic oil syndrome are not at greater risk for death over the 13-year study period than any of the comparison groups, women <40 years old were at greater risk of death.  (+info)

(8/6129) Failing firefighters: a survey of causes of death and ill-health retirement in serving firefighters in Strathclyde, Scotland from 1985-94.

During the decade beginning 1 January 1985, 887 full-time firefighters, all male, left the service of Strathclyde Fire Brigade (SFB). There were 17 deaths--compared to 64.4 expected in the Scottish male population aged 15-54 years--giving a standardized mortality ratio (SMR) of 26, and 488 ill-health retirements (IHR). None of the deaths was attributable to service, the major causes being: myocardial infarction--five, (expected = 17.3; SMR = 29); cancers--three (colon, kidney and lung) (expected = 13.6; SMR = 22); road traffic accidents--two (expected = 4.17; SMR = 48) and suicide--two (expected = 4.9; SMR = 41). Amalgamating the deaths and IHRs showed that the six most common reasons for IHR were musculoskeletal (n = 202, 40%), ocular (n = 61, 12.1%), 'others' (n = 58, 11.5%), injuries (n = 50, 9.9%), heart disease (n = 48, 9.5%) and mental disorders (n = 45, 8.9%). Over 300 IHRs (over 60%) occurred after 20 or more years service. When the IHRs were subdivided into two quinquennia, there were 203 and 302 in each period. Mean length of service during each quinquennium was 19.4 vs. 21.3 years (p = 0.003) and median length was 21 years in both periods; interquartile range was 12-26 years in the first and 17-27 years in the second period (p = 0.002), but when further broken down into diagnostic categories, the differences were not statistically significant, with the exception of means of IHRs attributed to mental disorders (14.5 vs. 19 years, p = 0.03).  (+info)


  • All Causes of Death, Australia, 2013 (3303.0) publication tables are available in these spreadsheets. (abs.gov.au)
  • no. 3303.0) are sourced from death registrations administered by the various state and territory Registrars of Births, Deaths and Marriages. (abs.gov.au)

Aboriginal and Torres Strait I

  • Diseases of the Digestive System (K00-K93) were the underlying cause of death for 145 Aboriginal and Torres Strait Islander Australians in 2010, accounting for 5.6% of deaths. (abs.gov.au)
  • The most common type of digestive disease that contributed to Aboriginal and Torres Strait Islander deaths were Diseases of the Liver (K70-K76), with 95 deaths in 2010. (abs.gov.au)
  • The age standardised death rate for Diseases of the Liver was almost five times higher (rate ratio of 4.8) for Aboriginal and Torres Strait Islander Australians compared with non-Indigenous Australians (30.1 and 6.3). (abs.gov.au)
  • Data is also presented for deaths of Aboriginal and Torres Strait Islander persons, and for suicide deaths. (abs.gov.au)

Registrars of Births

  • 6 The registration of deaths is the responsibility of the eight individual state and territory Registrars of Births, Deaths and Marriages. (abs.gov.au)
  • Registrars of Births, Deaths and Marriages and Coroners have legislative and administrative obligations to meet, as well as being the source of statistics. (abs.gov.au)

perinatal deaths

  • 1 This publication contains statistics on causes of death for Australia, together with selected statistics on perinatal deaths. (abs.gov.au)
  • 2 Statistics on perinatal deaths for the 2007-2009 reference years were published separately in Perinatal Deaths, Australia , 2009 (cat. (abs.gov.au)
  • In 2013, 97.5% of perinatal deaths were certified by a doctor, with the remaining 2.5% certified by a coroner. (abs.gov.au)
  • For the 2007-2009 reference years, perinatals data was released in the Perinatal Deaths, Australia (cat. (abs.gov.au)


  • Womack said that the death does not appear to have been a suicide, and the cause of death will not be known until after autopsy and toxicology tests are completed. (catholic.org)
  • To a poet suicide is death by a natural cause. (blogspot.com)

includes all deaths

  • 10 From 2007 onwards, data for a particular reference year includes all deaths registered in Australia for the reference year that are received by the ABS by the end of the March quarter of the subsequent year. (abs.gov.au)
  • The ABS causes of death collection includes all deaths that occurred and were registered in Australia, including deaths of persons whose usual residence is overseas. (abs.gov.au)

Wrongful Death

  • Diabetes Drug Actos Caused Bladder Cancer and Wrongful Death of Ohio Man, Alleges Lawsuit Filed by Parker Wa. (bio-medicine.org)
  • Karen Taradash, as special administrator of the Estate of John Taradash, filed a wrongful death lawsuit Oct. 30 in the Circuit Court of Cook County against Joel Kennedy Construction Corp. and Antero Rosas. (cookcountyrecord.com)


  • At the end of the study period there were 533 deaths (10.3% of cases). (bmj.com)

majority of these deaths

  • The vast majority of these deaths and injuries occur in low- and middle-income countries. (who.int)
  • The majority of these deaths were from mental and behavioural disorders and accidental overdoses (81%) with a further 273 suicides by drugs. (abs.gov.au)


  • This is a 9.8% decrease on the record 1,739 drug-induced deaths registered in 1999. (abs.gov.au)


  • Injuries are the principal cause of death in almost half of the people under 45 years of age and account for a range of physical, cognitive and psychological disabilities that seriously affect the quality of life of injured people and their families. (abs.gov.au)
  • Unless more comprehensive global action is taken, the number of deaths and injuries is likely to rise significantly. (who.int)
  • Youth and Road Safety highlights examples in countries where improved measures such as lowering speed limits, cracking down on drink-driving, promoting and enforcing the use of seat-belts, child restraints, and motorcycle helmets, as well as better road infrastructure and creating safe areas for children to play have significantly reduced the number of deaths and injuries. (who.int)
  • They reveal the physical, psychological, emotional and economic devastation that occurs during the aftermath of road traffic deaths and injuries. (who.int)
  • Another third were caused by "intentional" injuries -- suicides and homicides. (baltimoresun.com)
  • The suit claims that John Taradash was traveling west on Fullerton Avenue at the Pulaski Road intersection when Rosas made an improper left turn, striking Taradash's vehicle and causing him to sustain injuries that led to his death. (cookcountyrecord.com)


  • Autopsy results have been inconclusive in revealing what caused the death of Amy Winehouse. (musicfeeds.com.au)
  • Police have reported that the initial autopsy results could not confirm the cause of death and further toxicology tests need to be performed that could take weeks. (musicfeeds.com.au)
  • Benediction, Autopsy, Death Vomit. (get-albums.ru)


  • The state's Department of Health and Mental Hygiene last week released an 86-page report which describes and analyzes injury-death statistics for 1979 through 1987. (baltimoresun.com)
  • From 1979 through 1987, injury deaths increased by 18 percent, from 2,380 in the first year of the study to 2,805 in its final year. (baltimoresun.com)
  • The annual number of deaths ranged from a low of 2,243 in 1983 to the high of 2,805 recorded in 1987, for a nine-year average of 2,460 annually. (baltimoresun.com)


  • Kenneth Wallace, 53, of Barn Hill, Stamford, pleaded guilty to causing the death of Calum Warrilow by driving dangerously on the A1 near Grantham on September 13, 2016. (lincolnshirereporter.co.uk)


  • New South Wales had the largest number of drug-induced deaths registered (532) followed by Victoria (485) and Queensland (245). (abs.gov.au)


  • However, there can be lags in the registration of deaths with the state or territory registries and so not all deaths are registered in the year that they occur. (abs.gov.au)
  • There may also be further delays to the ABS receiving notification of the death from the registries due to processing or data transfer lags. (abs.gov.au)
  • These can include the types of data items collected and the definition of those data items, and business processes undertaken within Registries of Births, Deaths and Marriages including coding and quality assurance practices. (abs.gov.au)


  • The usual description of auditory-triggered arrhythmias and death have been those that occurred suddenly such as an alarm clock or an explosion, not usually a continual loud noise," said Dr. Thomas McDonald, a cardiologist at the Albert Einstein College of Medicine in New York. (go.com)
  • This process encourages the development of cardiac arrhythmias such as tachycardia and ventricular fibrillation, which cause loss of consciousness and cardiac arrest. (newsroomamerica.com)
  • It was known from previous studies that genetically modified mice without this protein tend to have malignant ventricular arrhythmias and sudden death. (newsroomamerica.com)


  • This publication presents statistics on the number of deaths, for reference year by state or territory of Australia, sex, selected age groups, and cause of death classified to the World Health Organisation's International Classification of Diseases (ICD). (abs.gov.au)
  • Data in the Causes of Death collection include demographic items as well as Causes of Death information, which is coded according to the International Classification of Diseases (ICD). (abs.gov.au)
  • The classification is used to classify diseases and causes of disease or injury as recorded on many types of medical records as well as death records. (abs.gov.au)


  • Because PtProtect identifies patients who are taking or potentially diverting prescribed pain medications, taking pain medications that are not prescribed to them, or using drugs of abuse it has the potential to significantly reduce accidental deaths. (biospace.com)
  • Brockie's death was thought to be drug-related due to evidence found at the scene of his death, and unfortunately, it's just been confirmed that he died from an accidental heroin overdose. (kbat.com)


  • The following diagram shows the process undertaken in producing cause of death statistics for Australia. (abs.gov.au)


  • Statistics presented in Causes of Death, Australia, 2013 (cat. (abs.gov.au)
  • Deaths of Australian residents that occurred outside Australia may be registered by individual Registrars, but are not included in ABS deaths or causes of death statistics. (abs.gov.au)
  • There can be differences between the defined scope of the population (i.e. every death occurring in Australia) and the actual coverage achieved by the registration system. (abs.gov.au)
  • Using ABS multiple cause of death data for registration years 1998 to 2002, this publication presents an overview of deaths from external causes of injury in Australia. (abs.gov.au)
  • A companion data file Drug-induced Deaths, Australia, 1997-2000 (Cat. (abs.gov.au)
  • This summary report presents key findings from the Australian Institute of Health and Welfare's report: Australian Burden of Disease Study: Impact and causes of illness and death in Australia 2011. (aihw.gov.au)


  • Twenty-eight year old Juliano Seunarine was sentenced by Chief Magistrate, Ann Mc Lennan after he was found guilty of causing death by dangerous driving. (demerarawaves.com)


  • As part of the First United Nations Global Road Safety Week (23-29 April 2007), WHO is launching the report to draw attention to the high global rates of death, injury and disability among young people caused by road traffic crashes. (who.int)


  • Each death record contains both demographic data and medical information from the Medical Certificate of Cause of Death where available. (abs.gov.au)
  • The data file reports the number of drug-induced deaths as well as range of demographic information relating to the deceased person. (abs.gov.au)


  • Michigan averages about four heat-related deaths each year. (dailytribune.com)
  • 7 Ideally, for compiling annual times series, the number of deaths should be recorded and reported as those which occurred within a given reference period, such as a calendar year. (abs.gov.au)
  • 8 With exception to the statistics published in the Year of Occurrence section and Data Cube 14, all deaths referred to in this publication relate to the number of deaths registered, not those which actually occurred, in the years shown. (abs.gov.au)
  • deaths registered in the years prior to the reference year but not received by ABS until the reference year or the first quarter of the subsequent year, provided that these records have not been included in any statistics from earlier periods. (abs.gov.au)
  • Death records received by ABS during the March quarter 2014 which were initially registered in 2013 (but for which registration was not fully completed until 2014) were assigned to the 2013 reference year. (abs.gov.au)
  • Approximately 4% to 6% of deaths occurring in one year are not registered until the following year or later. (abs.gov.au)
  • deaths registered prior to the reference year but not previously received from the Registrar nor included in any statistics reported for an earlier period. (abs.gov.au)
  • In particular, these accounts deepen our understanding of the enormous suffering that occurs behind each death and injury every year. (who.int)
  • Of the 22,139 injury deaths in Maryland during the nine-year period, about a third were due to transportation-related accidents. (baltimoresun.com)
  • The man, who drove at a fast rate under the influence of alcohol and caused the death of Christobel Hughes- mother of Attorney-at-Law, Nigel Hughes- almost one year ago- was Monday sentenced to four years imprisonment. (demerarawaves.com)
  • Particulars of the offence are that on August 15, 2015, he drove motor pick-up, PPP 4641, in a dangerous manner thereby causing the death of the 85-year old Hughes. (demerarawaves.com)
  • A motorist has admitted causing the death of a 17-year-old moped rider by dangerous driving when he appeared before Lincoln Crown Court. (lincolnshirereporter.co.uk)


  • Revised 2009 and final 2008 Causes of Death data are also presented in this publication by underlying cause of death. (abs.gov.au)
  • In addition 2006 cause of death data has undergone a revisions process with final 2006 data presented here. (abs.gov.au)
  • The ABS has released more in-depth data on drug induced deaths between 1997-2000 along with a comprehensive information paper, Drug-induced Deaths: A Guide to ABS Causes of Death Data , to assist researchers. (abs.gov.au)
  • The information paper provides a guide to data concepts and discusses issues which influence the ABS definition of drug-induced deaths. (abs.gov.au)
  • For deceased subjects data was extracted from the death report form and incorporated information such as cause and place of death. (bmj.com)


  • One more person, Abdul Qadir, from Hussaini Gojal died in GHQ Hospital Gilgit while struggling for his life as a result of drinking raw alcohol on Tuesday, mounting the death toll to three. (mountaintv.net)


  • Public Safety Director Ebenezer Paikai said the case will be turned over to the State Attorney`s office after an investigation into the death. (sun-sentinel.com)


  • The ICD is the international standard classification for epidemiological purposes and is designed to promote international comparability in the collection, processing, classification, and presentation of cause of death statistics. (abs.gov.au)


  • Differentials in injury death rates by remoteness categories as well as by State and Territory will be presented. (abs.gov.au)
  • As well, the nature of injury for selected external causes will be examined. (abs.gov.au)
  • Injury the No. 3 cause of death State studied 9 years of injury-death statistics. (baltimoresun.com)
  • Injury is the third-leading cause of death in Maryland, according to a first-ever study on the causes and extent of injury deaths in the state. (baltimoresun.com)
  • The figures, taken from death certificates, reveal that only heart disease and cancer were greater killers than was injury during those nine years. (baltimoresun.com)
  • Males suffered almost three-fourths of the injury deaths. (baltimoresun.com)
  • However, the annual injury rate was higher among blacks and other minorities (about 70 deaths per 100,000 people) than among whites (about 53 per 100,000). (baltimoresun.com)
  • The five subdivisions that recorded the highest rates of injury deaths per 100,000 people during the nine years were Dorchester County (88.6), Somerset County (88.5), Baltimore (84.4), Kent County (80.9) and Caroline County (80.3). (baltimoresun.com)
  • Baltimore had the highest number of injury deaths (5,808), far surpassing second-place Prince George's County (3,257). (baltimoresun.com)
  • The department says it envisions the study being used by government officials and health-care professionals throughout the state to create programs to prevent injury deaths. (baltimoresun.com)


  • One in three drug-induced deaths occurred in people aged 25-34 years in 2000, according to figures released today by Australian Bureau of Statistics (ABS). (abs.gov.au)


  • 3 In order to complete a death registration, the death must be certified by either a doctor using the Medical Certificate of Cause of Death, or by a coroner. (abs.gov.au)
  • For example, a death certificate may need to be produced in order to finalise certain other legal requirements e.g. finalisation of a person's estate. (abs.gov.au)


  • Numbers of deaths and death rates for selected external causes for special populations at risk will be presented. (abs.gov.au)


  • As part of the registration process, information about the cause of death is supplied by the medical practitioner certifying the death or by a coroner. (abs.gov.au)
  • Information about the deceased is supplied by a relative or other person acquainted with the deceased, or by an official of the institution where the death occurred on a Death Registration Form . (abs.gov.au)
  • Levels of registration can be influenced by external factors and coverage achieved will be influenced by the steps taken by the owners of death registration systems to ensure all deaths are registered. (abs.gov.au)


  • It is a legal requirement of each state and territory that all deaths are registered. (abs.gov.au)


  • For deceased subjects, the median age of diagnosis was 49 years (9-85) and the median age of death was 58 years (16-93). (bmj.com)
  • Still, our results show HD has its own natural history, being the age of death and the survival after the diagnosis unique among neurodegeneration. (bmj.com)

genetic disorder

  • While details remain unclear, experts in the United States say that given the circumstances, the death matches the profile of someone with a rare genetic disorder known as long QT syndrome, although they cannot say for sure. (go.com)
  • The gene, called CDH2, causes arrhythmogenic right ventricle cardiomyopathy (ARVC), which is a genetic disorder that predisposes patients to cardiac arrest and is a major cause of unexpected death in seemingly healthy young people. (newsroomamerica.com)

among young people

  • Newsroom America) -- Researchers from Canada, South Africa and Italy have identified a new gene that can lead to sudden death among young people and athletes. (newsroomamerica.com)
  • Road traffic crashes are the leading cause of death among young people between 10 and 24 years, according to a new report published by WHO. (who.int)


  • Causes of death is presented in the publication in a number of different ways including: by underlying cause, leading causes and multiple causes. (abs.gov.au)


  • However little evidence is available regarding late-stage HD including causes and places of death. (bmj.com)


  • Aims This retrospective study aims to ascertain HD causes and places of death in a European Huntington's disease cohort - the REGISTRY. (bmj.com)


  • Inherited forms of cardiomyopathy often cause sudden cardiac arrest death in young people under the age of 35. (newsroomamerica.com)


  • Officials at Marine Corps headquarters released a statement following news of the death: "We are aware of reports regarding the tragic passing of retired Marine Cpl. (catholic.org)
  • This is important news for families who have had a young family member suffer a sudden cardiac death, for them to know a genetic cause has been identified," said Paré, who is an associate professor of pathology and molecular medicine with the Michael G. DeGroote School of Medicine. (newsroomamerica.com)


  • In some cases it can be caused by exercise, and in other variants, being in the water seems to cause it. (go.com)
  • For 20 years, Mayosi followed a South African family affected by ARVC that had experienced several cases of juvenile sudden death. (newsroomamerica.com)
  • This may lead to a reduction of cases of sudden death in patients with the mutation, the researchers concluded. (newsroomamerica.com)


  • To the editor: I found the article by K. Danner Clouser, "Allowing or Causing: Another Look" ( Ann Intern Med 87:622-624, 1977), quite interesting. (annals.org)


  • a date on which the registered death is lodged with the ABS and deemed in scope. (abs.gov.au)


  • Excluding all genetic causes known at the time, the Italian researchers sequenced all the coding regions of the genome in two ill members of the family. (newsroomamerica.com)
  • and as time from symptom onset to death was 35 years (95% CI: 29.2-40.8). (bmj.com)
  • Prolapse does not cause damage to the heart over time. (blogspot.com)


  • Death records are provided electronically to the ABS by individual Registrars on a monthly basis. (abs.gov.au)


  • Malcolm Batt of Tenterden, killed in triple road death. (birminghammail.co.uk)


  • Once again, fab site Springhole delivers with a randomly selected death for your character. (thepuppetshow.co.uk)

Should i put my self in the hospital for depression cos i feel like OD or cutting soo deep i bleed to death.?

  • I dont know weather i should or shouldnt cos i mean there are people who show there love for me but bunch of people who dont and i just wanna give up should i or shouldnt i put my self in the hosputal.?

Death is inevitable, so, would you prefer being awake or asleep when you die?

Could you bleed to death if you cut your tongue out?

  • Assuming you didn't drown in your own blood, could you bleed to death if you just cut your tongue out? Like, do you have a main artery in it? Or you just bleed a lot?

True or False? You support the death penalty for child rape.?

What are the likely causes of death when an autopsy is inconclusive?

  • Often we read news stories where an autopsy on relatively fresh and unmutilated the body of an alleged murder victim is inconclusive as to the cause of death. What are the likely causes of death when such an autopsy is inconclusive? Are autopsies actually that hard or is the inconclusive finding a more political thing than a medial truth? If not, what medical causes of death are so hard to identify? For example the Kelli Lynn Murphy case.
  • I don't think "inconclusive" means it leans one way or another, it simply means they can't say for sure what the cause was. Doesn't even mean it's suspicious at all.

What are the chances of death and complications of gastric bypass?

  • What are the chances of death and complications for me getting gastric bypass surgery? I already know I'm getting it and I'm about to go through therapy. Here are some details that might be of help: • I'm 15. • I'm 330lbs. • I'm 6'5". Please give me an estimate on what my chances of death or major complications are! I really want to know!
  • The chances of death during gastric bypass surgery are very slim. The procedure is very safe. Every patient is different, so the chances or complications will differ. Much of it will have to do with what shape you are in prior to the surgery. Your doctor will take all of that into consideration and will tell you what complications can arise. At your age they may not even consider the surgery. Your body is going through a lot of changes. See your doctor and have him/her refer you to a bariatric surgeon. The surgeon will determine if you are a good candidate and will probably put you on a weigh loss program first. The process from the time of your initial consultation and when the surgery takes place can be several months. I had a gastric bypass three years ago and now head the local support group for weight loss patients. Feel free to email me if you have any questions. stagelady/eileen

What causes death in humans and how could it be prevented?

  • Provided a person does not die from an illness or accident, what would cause a person to die? If a person is forced to breathe (such as on a life support system), would they be able to live longer or indefinitely? What things play a factor in death? Thanks.

What's the difference between a death investigator and a medical examiner or Coroner?

  • My 25 year old son died and a death investigator was sent out and not a medical examiner or coroner??? I have unanswered questions concerning his death. Any information given would be appreciated. No autopsy was performed on my son.
  • A death investigator works for the county and is sent to the scenes of death to investigate, photograph and document the circumstances surrounding the death. It is not uncommon that the medical examiner did not come, they are the doctors who perform autopsies (basically they work 9-5). They do not go to the scene of death. I presume you live in a city where they employ a medical examiner, as a coroner is an elected position (not necessarily a doctor), yet they may not always go to the scene either if there are death investigators. The investigator must have determined from the circumstances that an autopsy was not necessary or they would have ordered one.