Cadmium
Cadmium Poisoning
Cadmium Chloride
Cadmium Radioisotopes
Metallothionein
Metals, Heavy
Lead
Phytochelatins
Zinc
Spectrophotometry, Atomic
Environmental Pollutants
Mercury
Environmental Exposure
Soil Pollutants
Body Burden
Metals
Copper
Metallurgy
Food Contamination
Arsenic
Tellurium
Testing their metal. (1/120)
Metals continually rank at the top of the U.S. Environmental Protection Agency's annual list of agents that pose the greatest hazard to the people of the United States. Metals aren't going away, either. They do not biodegrade, and they often concentrate in human and animal cells and tissue. Many metals are known human and animal carcinogens, while many others are suspected to play a role in cancer. Little is known, however, about the mechanisms by which metals cause cancer. (+info)Granulocyte and plasma cytokine activity in acute cadmium intoxication in rats. (2/120)
Changes in the number and ex vivo function of peripheral blood neutrophils were investigated following intraperitoneal administration of cadmium-chloride in rats. Besides a dose-dependent increase in the number of peripheral blood neutrophils, changes were found in the functional state of isolated polymorphonuclear leukocytes (PMNs). Increased spontaneous adhesion and activation, and TNF activity in a conditioned medium were observed in cultures of granulocytes in comparison to granulocytes from control (saline-treated) animals. Increased levels of plasma activity of inflammatory cytokines, tumor necrosis factor (TNF) and interleukin-6 (IL-6) were noted following cadmium administration. Cytological signs of pulmonary inflammation were revealed histologically and the majority of neutrophils recovered from the lungs by enzyme digestion exhibited a capacity of nitroblue tetrazolium (NBT) reduction. Our data demonstrate that acute cadmium intoxication leads to a systemic inflammatory response characterized by numerical and functional changes in the granulocyte compartment and to increased levels of inflammation-related cytokine activity in the circulation. Correlations between the increased number of peripheral blood neutrophils and IL-6 plasma activity (r=0.776, p<0.00001) and the number of neutrophils recovered from the lung tissue (r=0.893, p<0.00001) suggested that systemic cadmium-induced inflammation might be involved in the pulmonary toxicity of cadmium. (+info)Neurobehavioural effects of occupational exposure to cadmium: a cross sectional epidemiological study. (3/120)
BACKGROUND: A patient with unexplained minor behavioural changes associated with an axonal sensorimotor polyneuropathy had a history of chronic occupational exposure to cadmium (Cd). Although animal studies have shown that Cd is a potent neurotoxicant, little is known about its toxicity for the human central nervous system. The aim of this study was to investigate the toxic potential of chronic occupational exposure to Cd on neurobehavioural functions. METHODS: A cross sectional epidemiological study was conducted ina group of Cd workers and an age matched control group. Eighty nine adult men (42 exposed to Cd and 47 control workers) were given a blinded standardised examination that consisted of computer assisted neurobehavioural tests (neurobehavioural examination system), a validated questionnaire to assess neurotoxic complaints (neurotoxicity symptom checklist--60, NSC-60), and a standardised self administered questionnaire to detect complaints consistent with peripheral neuropathy and dysfunction of the autonomic nervous system. Historical and current data on biomonitoring of exposure to Cd, either the highest value of Cd in urine (CdU in microgram Cd/g creatinine) of each Cd worker during work (CdUmax) or the current value (CdUcurrent) of each control, were available as well as data on microproteinuria. RESULTS: Cd workers (CdUmax: mean (range), 12.6 (0.4-38.4)) performed worse than the controls (CdUcurrent: mean (range), 0.7 (0.1-2.0)) on visuomotor tasks, symbol digit substitution (p = 0.008), and simple reaction time to direction (p = 0.058) or location (p = 0.042) of a stimulus. In multiple linear regression analysis, symbol digit substitution, simple direction reaction time test, and simple location reaction time test were significantly related to CdUmax, (beta = 0.35 (p < 0.001), beta = 0.25 (p = 0.012), and beta = 0.23 (p = 0.021) respectively). More complaints consistent with peripheral neuropathy (p = 0.004), complaints about equilibrium (p = 0.015), and complaints about concentration ability (p = 0.053) were found in the group exposed to Cd than in the control group, and these variables correlated positively with CdUmax (peripheral neuropathy: beta = 0.38, p < 0.001; equilibrium: beta = 0.22, p = 0.057; concentration ability: beta = 0.27, p = 0.020). CONCLUSION: Slowing of visuomotor functioning on neurobehavioural testing and increase in complaints consistent with peripheral neuropathy, complaints about equilibrium, and complaints about concentration ability were dose dependently associated with CdU. Age, exposure to other neurotoxicants, or status of renal function could not explain these findings. The present study also indicates that an excess of complaints may be detected in Cd workers before signs of microproteinuria induced by Cd occur. (+info)Risk of mortality, cancer incidence, and stroke in a population potentially exposed to cadmium. (4/120)
OBJECTIVES: To follow up mortality and cancer incidence in a cohort potentially exposed to cadmium and to perform a geographical (ecological) analysis to further assess the health effects of potential exposure to cadmium. METHODS: The English village of Shipham has very high concentrations of cadmium in the soil. A previous cohort study of residents of Shipham in 1939 showed overall mortality below that expected, but a 40% excess of mortality from stroke. This study extends the follow up of the cohort for mortality to 1997, and includes an analysis of cancer incidence from 1971 to 1992, and a geographical study of mortality and cancer incidence. Standardised mortality and incidence ratios (SMRs and SIRs) were estimated with regional reference rates. Comparisons were made with the nearby village of Hutton. RESULTS: All cause cohort mortality was lower than expected in both villages, although there was excess cancer incidence in both Shipham (SIR 167, 95% confidence interval (95% CI) 106 to 250) and Hutton (SIR 167, 95% CI 105 to 253). There was an excess of mortality from hypertension, cerebrovascular disease, and nephritis and nephrosis, of borderline significance, in Shipham (SMR 128, 95% CI 99 to 162). In the geographical study, all cause mortality in Shipham was also lower than expected (SMR 84, 95% CI 71 to 100). There was an excess in genitourinary cancers in both Shipham (SIR 160, 95% CI 107 to 239) and Hutton (SIR 153, 95% CI 122 to 192). CONCLUSION: No clear evidence of health effects from possible exposure to cadmium in Shipham was found despite the extremely high concentrations of cadmium in the soil. (+info)Male infertility and environmental exposure to lead and cadmium. (5/120)
Humans are exposed occupationally and environmentally to metal aerosols including lead (Pb2+) and cadmium (Cd2+). These toxicants accumulate in male reproductive organs. Epidemiological studies have been equivocal about effects of Pb2+ and Cd2+ on hormone concentrations, male fertility and sperm parameters. Comparison of Pb2+ and Cd2+ concentrations in fertile and infertile men are problematic. Problem areas include failure to control confounding variables, but genetic polymorphisms as in somatic diseases may modulate Pb2+ and Cd2+ damage. Multiple calcium (Ca2+) and potassium (K+) channel isoforms have been identified in human testes and spermatozoa. These Ca2+ and K+ channels are involved in early events of acrosome reactions. Ca2+ channel are susceptible to Cd2+ poisoning and K+ channels to Pb2+. These channels offer entry paths for metallic toxicants into mature spermatozoa. Ion channel polymorphisms may cause differential sensitivities to Cd2+ and Pb2+, explaining in part prospective blinded studies showing high Cd2+ in varicocele-related human infertility and high Pb2+ in unexplained infertility. In both forms of male infertility the ability to undergo an acrosome reaction decreases. Reverse transcriptase-polymerase chain reaction assays for Ca2+ and K+ channel isoforms may identify susceptibility subgroups with lower resistance to environmental exposures. (+info)Metallothionein-null mice are more sensitive than wild-type mice to liver injury induced by repeated exposure to cadmium. (6/120)
Liver is a major target organ of cadmium (Cd) toxicity following acute and chronic exposure. Metallothionein (MT), a low-molecular-weight, cysteine-rich, metal-binding protein has been shown to play an important role in protection against acute Cd-induced liver injury. This study investigates the role of MT in liver injury induced by repeated exposure to Cd. Wild-type and MT-I/II knockout (MT I/II-null) mice were injected sc with a wide range of CdCl(2) doses, 6 times/week, for up to 10 weeks, and their hepatic Cd content, hepatic MT concentration, and liver injury were examined. Repeated administration of CdCl(2) produced acute and nonspecific chronic inflammation in the parenchyma and portal tracts and around central veins. Higher doses produced granulomatous inflammation and proliferating nodules in liver parenchyma. Apoptosis and mitosis occurred concomitantly in liver following repeated Cd exposure, whereas necrosis was mild. As a result, significant elevation of serum enzyme levels was not observed. In wild-type mice, hepatic Cd concentration increased in a dose- and time-dependent manner, reaching 400 microgram/g liver, along with 150-fold increases in hepatic MT concentrations, the latter reaching 1200 microgram/g liver. In contrast, in MT I/II-null mice, hepatic Cd concentrations were about 10 microgram/g liver. Despite the lower accumulation of Cd in livers of MT I/II-null mice, the maximum tolerated dose of Cd was one-eighth lower than that for wild-type mice at 10 weeks, and liver injury was more pronounced in the MT I/II-null mice, as evidenced by increases in liver/body weight ratios and histopathological analyses. In conclusion, these data indicate that (1) nonspecific chronic inflammation, granulomatous inflammation, apoptosis, liver cell regeneration, and presumably, preneoplastic proliferating nodules are major features of liver injury induced by repeated Cd exposure, and (2) intracellular MT is an important protein protecting against this Cd-induced liver injury. (+info)Acute cadmium exposure inactivates thioltransferase (Glutaredoxin), inhibits intracellular reduction of protein-glutathionyl-mixed disulfides, and initiates apoptosis. (7/120)
Oxidative stress broadly impacts cells, initiating regulatory pathways as well as apoptosis and necrosis. A key molecular event is protein S-glutathionylation, and thioltransferase (glutaredoxin) is a specific and efficient catalyst of protein-SSG reduction. In this study 30-min exposure of H9 and Jurkat cells to cadmium inhibited intracellular protein-SSG reduction, and this correlated with inhibition of the thioltransferase system, consistent with thioltransferase being the primary intracellular catalyst of deglutathionylation. The thioredoxin system contributed very little to total deglutathionylase activity. Thioltransferase and GSSG reductase in situ displayed similar dose-response curves (50% inhibition near 10 micrometer cadmium in extracellular buffer). Acute cadmium exposure also initiated apoptosis, with H9 cells being more sensitive than Jurkat. Moreover, transfection with antisense thioltransferase cDNA was incompatible with cell survival. Collectively, these data suggest that thioltransferase has a vital role in sulfhydryl homeostasis and cell survival. In separate experiments, cadmium inhibited the isolated component enzymes of the thioltransferase and thioredoxin systems, consistent with the vicinal dithiol nature of their active sites: thioltransferase (IC(50) approximately 1 micrometer), GSSG reductase (IC(50) approximately 1 micrometer), thioredoxin (IC(50) approximately 8 micrometer), thioredoxin reductase (IC(50) approximately 0.2 micrometer). Disruption of the vicinal dithiol on thioltransferase (via oxidation to C22-SS-C25; or C25S mutation) protected against cadmium, consistent with a dithiol chelation mechanism of inactivation. (+info)Heavy metal poisoning in glass worker characterised by severe. (8/120)
The paper presents the clinical description of the masticatory organ and biochemical assessment of dental tissue in a patient employed in a glassworks for 20 years. During 12 years the patient has suffered baldness ("Alopecia areata") and atypical extensive and non-healing cutaneous lesions. Dental examination revealed changes typical of chronic poisoning by cadmium and bismuth compounds. (+info)Cadmium is a toxic heavy metal that is a byproduct of the mining and smelting of zinc, lead, and copper. It has no taste or smell and can be found in small amounts in air, water, and soil. Cadmium can also be found in some foods, such as kidneys, liver, and shellfish.
Exposure to cadmium can cause a range of health effects, including kidney damage, lung disease, fragile bones, and cancer. Cadmium is classified as a known human carcinogen by the International Agency for Research on Cancer (IARC) and the National Toxicology Program (NTP).
Occupational exposure to cadmium can occur in industries that produce or use cadmium, such as battery manufacturing, metal plating, and pigment production. Workers in these industries may be exposed to cadmium through inhalation of cadmium-containing dusts or fumes, or through skin contact with cadmium-containing materials.
The general population can also be exposed to cadmium through the environment, such as by eating contaminated food or breathing secondhand smoke. Smoking is a major source of cadmium exposure for smokers and those exposed to secondhand smoke.
Prevention measures include reducing occupational exposure to cadmium, controlling emissions from industrial sources, and reducing the use of cadmium in consumer products. Regular monitoring of air, water, and soil for cadmium levels can also help identify potential sources of exposure and prevent health effects.
Cadmium poisoning is a condition that results from the exposure to cadmium, a toxic heavy metal. This can occur through inhalation, ingestion, or skin absorption. Cadmium is found in some industrial workplaces, such as battery manufacturing, metal smelting, and phosphate fertilizer production. It can also be found in contaminated food, water, and cigarette smoke.
Acute cadmium poisoning is rare but can cause severe symptoms such as abdominal pain, vomiting, diarrhea, and muscle cramps. Chronic exposure to cadmium can lead to a range of health problems, including kidney damage, bone disease, lung damage, and anemia. It has also been linked to an increased risk of cancer, particularly lung cancer.
The treatment for cadmium poisoning typically involves removing the source of exposure, providing supportive care, and in some cases, chelation therapy to remove cadmium from the body. Prevention measures include reducing exposure to cadmium in the workplace, avoiding contaminated food and water, and not smoking.
Cadmium chloride is an inorganic compound with the chemical formula CdCl2. It is a white crystalline solid that is highly soluble in water and has a bitter, metallic taste. Cadmium chloride is a toxic compound that can cause serious health effects, including kidney damage, respiratory problems, and bone degeneration. It is classified as a hazardous substance and should be handled with care.
Cadmium chloride is used in various industrial applications, such as electroplating, soldering, and as a stabilizer in plastics. It is also used in some research settings as a reagent in chemical reactions.
It's important to note that exposure to cadmium chloride should be avoided, and appropriate safety measures should be taken when handling this compound. This includes wearing protective clothing, such as gloves and lab coats, and working in a well-ventilated area or under a fume hood. In case of accidental ingestion or inhalation, seek medical attention immediately.
Cadmium compounds refer to combinations of the chemical element cadmium (Cd) with one or more other elements. Cadmium is a naturally occurring heavy metal that is commonly found in zinc ores and is often produced as a byproduct of mining and smelting operations for other metals.
Cadmium compounds can take many forms, including cadmium chloride (CdCl2), cadmium sulfate (CdSO4), cadmium oxide (CdO), and cadmium carbonate (CdCO3). These compounds are often used in a variety of industrial applications, such as electroplating, pigments, and batteries.
Exposure to cadmium compounds can be harmful to human health, as they can accumulate in the body over time and cause damage to the kidneys, liver, bones, and respiratory system. Long-term exposure to cadmium has been linked to an increased risk of cancer, particularly lung cancer. As a result, occupational exposure to cadmium compounds is regulated by various governmental agencies, and efforts are underway to reduce the use of cadmium in consumer products.
Cadmium radioisotopes are unstable forms of the heavy metal cadmium that emit radiation as they decay into more stable elements. These isotopes can be created through various nuclear reactions, such as bombarding a cadmium atom with a high-energy particle. Some common cadmium radioisotopes include cadmium-109, cadmium-113, and cadmium-115.
These radioisotopes have a wide range of applications in medicine, particularly in diagnostic imaging and radiation therapy. For example, cadmium-109 is used as a gamma ray source for medical imaging, while cadmium-115 has been studied as a potential therapeutic agent for cancer treatment.
However, exposure to cadmium radioisotopes can also be hazardous to human health, as they can cause damage to tissues and organs through ionizing radiation. Therefore, handling and disposal of these materials must be done with care and in accordance with established safety protocols.
Metallothioneins (MTs) are a group of small, cysteine-rich, metal-binding proteins found in the cells of many organisms, including humans. They play important roles in various biological processes such as:
1. Metal homeostasis and detoxification: MTs can bind to various heavy metals like zinc, copper, cadmium, and mercury with high affinity. This binding helps regulate the concentration of these metals within cells and protects against metal toxicity.
2. Oxidative stress protection: Due to their high cysteine content, MTs act as antioxidants by scavenging reactive oxygen species (ROS) and free radicals, thus protecting cells from oxidative damage.
3. Immune response regulation: MTs are involved in the modulation of immune cell function and inflammatory responses. They can influence the activation and proliferation of immune cells, as well as the production of cytokines and chemokines.
4. Development and differentiation: MTs have been implicated in cell growth, differentiation, and embryonic development, particularly in tissues with high rates of metal turnover, such as the liver and kidneys.
5. Neuroprotection: In the brain, MTs play a role in protecting neurons from oxidative stress, excitotoxicity, and heavy metal toxicity. They have been implicated in various neurodegenerative disorders, including Alzheimer's and Parkinson's diseases.
There are four main isoforms of metallothioneins (MT-1, MT-2, MT-3, and MT-4) in humans, each with distinct tissue expression patterns and functions.
Heavy metals are a group of elements with a specific gravity at least five times greater than that of water. They include metals such as mercury (Hg), cadmium (Cd), arsenic (As), chromium (Cr), thallium (Tl), and lead (Pb). These metals are considered toxic when they accumulate in the body beyond certain levels, interfering with various biological processes and causing damage to cells, tissues, and organs.
Heavy metal exposure can occur through various sources, including occupational exposure, contaminated food, water, or air, and improper disposal of electronic waste. Chronic exposure to heavy metals has been linked to several health issues, such as neurological disorders, kidney damage, developmental problems, and cancer. Monitoring and controlling exposure to these elements is essential for maintaining good health and preventing potential adverse effects.
In the context of medicine, "lead" most commonly refers to lead exposure or lead poisoning. Lead is a heavy metal that can be harmful to the human body, even at low levels. It can enter the body through contaminated air, water, food, or soil, and it can also be absorbed through the skin.
Lead poisoning occurs when lead builds up in the body over time, causing damage to the brain, nervous system, red blood cells, and kidneys. Symptoms of lead poisoning may include abdominal pain, constipation, fatigue, headache, irritability, memory problems, and in severe cases, seizures, coma, or even death.
Lead exposure is particularly dangerous for children, as their developing bodies are more sensitive to the harmful effects of lead. Even low levels of lead exposure can cause learning disabilities, behavioral problems, and developmental delays in children. Therefore, it's important to minimize lead exposure and seek medical attention if lead poisoning is suspected.
Phytochelatins are low molecular weight, heavy metal-binding peptides that are synthesized by plants and some other organisms in response to exposure to toxic metals. They are composed of repeating units of the amino acids glutamic acid, cysteine, and glycine, with the general structure (γ-Glu-Cys)n-Gly, where n typically ranges from 2 to 5.
Phytochelatins are produced by the enzyme phytochelatin synthase, which is activated in the presence of heavy metals such as cadmium, mercury, and lead. Once synthesized, phytochelatins bind to these metals, forming metal-phytochelatin complexes that are then transported to the vacuole for sequestration and detoxification.
In addition to their role in heavy metal detoxification, phytochelatins have been shown to have antioxidant properties and may play a role in protecting plants against oxidative stress. They have also attracted interest as potential therapeutic agents for heavy metal poisoning in humans and other animals.
Zinc is an essential mineral that is vital for the functioning of over 300 enzymes and involved in various biological processes in the human body, including protein synthesis, DNA synthesis, immune function, wound healing, and cell division. It is a component of many proteins and participates in the maintenance of structural integrity and functionality of proteins. Zinc also plays a crucial role in maintaining the sense of taste and smell.
The recommended daily intake of zinc varies depending on age, sex, and life stage. Good dietary sources of zinc include red meat, poultry, seafood, beans, nuts, dairy products, and fortified cereals. Zinc deficiency can lead to various health problems, including impaired immune function, growth retardation, and developmental delays in children. On the other hand, excessive intake of zinc can also have adverse effects on health, such as nausea, vomiting, and impaired immune function.
Atomic spectrophotometry is a type of analytical technique used to determine the concentration of specific atoms or ions in a sample by measuring the intensity of light absorbed or emitted at wavelengths characteristic of those atoms or ions. This technique involves the use of an atomic spectrometer, which uses a source of energy (such as a flame, plasma, or electrode) to excite the atoms or ions in the sample, causing them to emit light at specific wavelengths. The intensity of this emitted light is then measured and used to calculate the concentration of the element of interest.
Atomic spectrophotometry can be further divided into two main categories: atomic absorption spectrophotometry (AAS) and atomic emission spectrophotometry (AES). In AAS, the sample is atomized in a flame or graphite furnace and the light from a lamp that emits light at the same wavelength as one of the elements in the sample is passed through the atoms. The amount of light absorbed by the atoms is then measured and used to determine the concentration of the element. In AES, the sample is atomized and excited to emit its own light, which is then measured and analyzed to determine the concentration of the element.
Atomic spectrophotometry is widely used in various fields such as environmental monitoring, clinical chemistry, forensic science, and industrial quality control for the determination of trace elements in a variety of sample types including liquids, solids, and gases.
Environmental pollutants are defined as any substances or energy (such as noise, heat, or light) that are present in the environment and can cause harm or discomfort to humans or other living organisms, or damage the natural ecosystems. These pollutants can come from a variety of sources, including industrial processes, transportation, agriculture, and household activities. They can be in the form of gases, liquids, solids, or radioactive materials, and can contaminate air, water, and soil. Examples include heavy metals, pesticides, volatile organic compounds (VOCs), particulate matter, and greenhouse gases.
It is important to note that the impact of environmental pollutants on human health and the environment can be acute (short-term) or chronic (long-term) and it depends on the type, concentration, duration and frequency of exposure. Some common effects of environmental pollutants include respiratory problems, cancer, neurological disorders, reproductive issues, and developmental delays in children.
It is important to monitor, control and reduce the emissions of these pollutants through regulations, technology advancements, and sustainable practices to protect human health and the environment.
In the context of medicine, Mercury does not have a specific medical definition. However, it may refer to:
1. A heavy, silvery-white metal that is liquid at room temperature. It has been used in various medical and dental applications, such as therapeutic remedies (now largely discontinued) and dental amalgam fillings. Its use in dental fillings has become controversial due to concerns about its potential toxicity.
2. In microbiology, Mercury is the name of a bacterial genus that includes the pathogenic species Mercury deserti and Mercury avium. These bacteria can cause infections in humans and animals.
It's important to note that when referring to the planet or the use of mercury in astrology, these are not related to medical definitions.
Environmental exposure refers to the contact of an individual with any chemical, physical, or biological agent in the environment that can cause a harmful effect on health. These exposures can occur through various pathways such as inhalation, ingestion, or skin contact. Examples of environmental exposures include air pollution, water contamination, occupational chemicals, and allergens. The duration and level of exposure, as well as the susceptibility of the individual, can all contribute to the risk of developing an adverse health effect.
I'm sorry for any confusion, but "soil pollutants" is not a term typically used in medical definitions. Soil pollution refers to the presence or accumulation of hazardous substances, chemicals, or other pollutants in soil that can have negative effects on plant life, human health, and the environment.
However, if you're asking about potential health effects of exposure to soil pollutants, it could include a variety of symptoms or diseases, depending on the specific pollutant. For example, exposure to lead-contaminated soil can lead to developmental delays in children, while exposure to certain pesticides or industrial chemicals can cause neurological problems, respiratory issues, and even cancer.
If you have more specific information about a particular substance or context, I may be able to provide a more precise answer.
"Body burden" is a term used in the field of environmental health to describe the total amount of a chemical or toxic substance that an individual has accumulated in their body tissues and fluids. It refers to the overall load or concentration of a particular chemical or contaminant that an organism is carrying, which can come from various sources such as air, water, food, and consumer products.
The term "body burden" highlights the idea that people can be exposed to harmful substances unknowingly and unintentionally, leading to potential health risks over time. Some factors that may influence body burden include the frequency and duration of exposure, the toxicity of the substance, and individual differences in metabolism, elimination, and susceptibility.
It is important to note that not all chemicals or substances found in the body are necessarily harmful, as some are essential for normal bodily functions. However, high levels of certain environmental contaminants can have adverse health effects, making it crucial to monitor and regulate exposure to these substances.
In the context of medicine, there is no specific medical definition for 'metals.' However, certain metals have significant roles in biological systems and are thus studied in physiology, pathology, and pharmacology. Some metals are essential to life, serving as cofactors for enzymatic reactions, while others are toxic and can cause harm at certain levels.
Examples of essential metals include:
1. Iron (Fe): It is a crucial component of hemoglobin, myoglobin, and various enzymes involved in energy production, DNA synthesis, and electron transport.
2. Zinc (Zn): This metal is vital for immune function, wound healing, protein synthesis, and DNA synthesis. It acts as a cofactor for over 300 enzymes.
3. Copper (Cu): Copper is essential for energy production, iron metabolism, antioxidant defense, and connective tissue formation. It serves as a cofactor for several enzymes.
4. Magnesium (Mg): Magnesium plays a crucial role in many biochemical reactions, including nerve and muscle function, protein synthesis, and blood pressure regulation.
5. Manganese (Mn): This metal is necessary for bone development, protein metabolism, and antioxidant defense. It acts as a cofactor for several enzymes.
6. Molybdenum (Mo): Molybdenum is essential for the function of certain enzymes involved in the metabolism of nucleic acids, proteins, and drugs.
7. Cobalt (Co): Cobalt is a component of vitamin B12, which plays a vital role in DNA synthesis, fatty acid metabolism, and nerve function.
Examples of toxic metals include:
1. Lead (Pb): Exposure to lead can cause neurological damage, anemia, kidney dysfunction, and developmental issues.
2. Mercury (Hg): Mercury is highly toxic and can cause neurological problems, kidney damage, and developmental issues.
3. Arsenic (As): Arsenic exposure can lead to skin lesions, cancer, neurological disorders, and cardiovascular diseases.
4. Cadmium (Cd): Cadmium is toxic and can cause kidney damage, bone demineralization, and lung irritation.
5. Chromium (Cr): Excessive exposure to chromium can lead to skin ulcers, respiratory issues, and kidney and liver damage.
Copper is a chemical element with the symbol Cu (from Latin: *cuprum*) and atomic number 29. It is a soft, malleable, and ductile metal with very high thermal and electrical conductivity. Copper is found as a free element in nature, and it is also a constituent of many minerals such as chalcopyrite and bornite.
In the human body, copper is an essential trace element that plays a role in various physiological processes, including iron metabolism, energy production, antioxidant defense, and connective tissue synthesis. Copper is found in a variety of foods, such as shellfish, nuts, seeds, whole grains, and organ meats. The recommended daily intake of copper for adults is 900 micrograms (mcg) per day.
Copper deficiency can lead to anemia, neutropenia, impaired immune function, and abnormal bone development. Copper toxicity, on the other hand, can cause nausea, vomiting, abdominal pain, diarrhea, and in severe cases, liver damage and neurological symptoms. Therefore, it is important to maintain a balanced copper intake through diet and supplements if necessary.
I'm sorry for any confusion, but "metallurgy" is not a term that has a medical definition. Metallurgy is a branch of materials science that deals with the properties, physical and chemical behavior, and production of metals. It involves studying the techniques and processes used to isolate, alloy, and fabricate various types of metal products. If you have any questions related to medicine or health, I'd be happy to try to help answer those for you!
Food contamination is the presence of harmful microorganisms, chemicals, or foreign substances in food or water that can cause illness or injury to individuals who consume it. This can occur at any stage during production, processing, storage, or preparation of food, and can result from various sources such as:
1. Biological contamination: This includes the presence of harmful bacteria, viruses, parasites, or fungi that can cause foodborne illnesses. Examples include Salmonella, E. coli, Listeria, and norovirus.
2. Chemical contamination: This involves the introduction of hazardous chemicals into food, which may occur due to poor handling practices, improper storage, or exposure to environmental pollutants. Common sources of chemical contamination include pesticides, cleaning solvents, heavy metals, and natural toxins produced by certain plants or fungi.
3. Physical contamination: This refers to the presence of foreign objects in food, such as glass, plastic, hair, or insects, which can pose a choking hazard or introduce harmful substances into the body.
Preventing food contamination is crucial for ensuring food safety and protecting public health. Proper hygiene practices, temperature control, separation of raw and cooked foods, and regular inspections are essential measures to minimize the risk of food contamination.
Arsenic is a naturally occurring semi-metal element that can be found in the earth's crust. It has the symbol "As" and atomic number 33 on the periodic table. Arsenic can exist in several forms, including inorganic and organic compounds. In its pure form, arsenic is a steel-gray, shiny solid that is brittle and easily pulverized.
Arsenic is well known for its toxicity to living organisms, including humans. Exposure to high levels of arsenic can cause various health problems, such as skin lesions, neurological damage, and an increased risk of cancer. Arsenic can enter the body through contaminated food, water, or air, and it can also be absorbed through the skin.
In medicine, arsenic has been used historically in the treatment of various diseases, including syphilis and parasitic infections. However, its use as a therapeutic agent is limited due to its toxicity. Today, arsenic trioxide is still used as a chemotherapeutic agent for the treatment of acute promyelocytic leukemia (APL), a type of blood cancer. The drug works by inducing differentiation and apoptosis (programmed cell death) in APL cells, which contain a specific genetic abnormality. However, its use is closely monitored due to the potential for severe side effects and toxicity.
I'm sorry for any confusion, but "Tellurium" is not a medical term. Tellurium is a chemical element with the symbol "Te" and atomic number 52. It is a rare, silver-white metalloid that is chemically related to selenium and sulfur. It is not used in medicine or healthcare. If you have any medical concerns or questions, I'd be happy to try to help answer those for you!
Chemical water pollutants refer to harmful chemicals or substances that contaminate bodies of water, making them unsafe for human use and harmful to aquatic life. These pollutants can come from various sources, including industrial and agricultural runoff, sewage and wastewater, oil spills, and improper disposal of hazardous materials.
Examples of chemical water pollutants include heavy metals (such as lead, mercury, and cadmium), pesticides and herbicides, volatile organic compounds (VOCs), polychlorinated biphenyls (PCBs), and petroleum products. These chemicals can have toxic effects on aquatic organisms, disrupt ecosystems, and pose risks to human health through exposure or consumption.
Regulations and standards are in place to monitor and limit the levels of chemical pollutants in water sources, with the aim of protecting public health and the environment.
Cadmium poisoning
Gold Peak
Four Big Pollution Diseases of Japan
Chicago Pile-1
Environmental impact of Mardi Gras beads
Metals in medicine
Itai-itai disease
Onsan illness
Hezhang County
Toho Zinc
Bismuth
Cadmium tetrafluoroborate
Octopus as food
Cadmium phosphide
Okayama University
Product recall
Christmas Island flying fox
Soonchunhyang University Hospital
Pastel
SL-1
Stolberg (Rhineland)
Environmental issues in Japan
Forensic chemistry
List of environmental disasters
Osteomalacia
Anosmia
Index of environmental articles
Metal fume fever
Gansu
Cadmium pigments
Cadmium poisoning - Wikipedia
Browsing by Subject "Cadmium Poisoning"
Browsing by Subject "Cadmium Poisoning"
Plant science: the key to preventing slow cadmium poisoning - WUR
California engineer allegedly tried to poison, kill colleague with 'toxic amount of cadmium,' police say
The liver in itai-itai disease (chronic cadmium poisoning): pathological features and metallothionein expression - PubMed
The liver in itai-itai disease (chronic cadmium poisoning): pathological features and metallothionein expression - PubMed
Cadmium poisoning from a refrigerator shelf used as an improvised barbecue grill
Cadmium Toxicity: Sources of Additional Information | Environmental Medicine | ATSDR
DailyMed - ENVIRONMENTAL DETOX- aluminum oxide, barium carbonate, benzene, cadmium, carbon monoxide, carbon disulfide, copper,...
Renal Function after Reduction in Cadmium Exposure: An 8-Year Follow-up of Residents in Cadmium-Polluted Areas | Environmental...
Cadmium's Disguise Dupes the Estrogen Receptor
Geriatric Rehabilitation: Overview, Auditory and Visual Impairments, Falls
An ultrastructural study of chronic cadmium chloride-induced neuropathy
NIOSHTIC-2 Search Results - Full View
The long, terrifying history of Russian dissidents being poisoned abroad
Solder poisoning: MedlinePlus Medical Encyclopedia
shrek glass recall Archives - UK Today News
the atrium | golden threads | social history | lead
Publication Detail
NIH Guide: CONSTRUCTION HEALTH AND SAFETY
RealClimate: Mercury, the other geologically persistent planetary poison
Renal Tubular Acidosis - NIDDK
Ecology and environment (China) - Europe Solidaire Sans Frontières
Shipbuilding and Ship Repair - General Hazard: Respiratory Irritation and Systemic Poisoning | Occupational Safety and Health...
Biochemical and Molecular Targets of Heavy Metals and Their Actions | SpringerLink
New Online Resource on Cadmium Exposure » CBIA
Effects of cadmium7
- citation needed] One of the main effects of cadmium poisoning is weak and brittle bones. (wikipedia.org)
- Sources of information about the adverse effects of cadmium and the management of people exposed to cadmium. (cdc.gov)
- The mutagenic and carcinogenic effects of cadmium: an update. (cdc.gov)
- 19. Heavy metal poisoning: the effects of cadmium on the kidney. (nih.gov)
- For more about the effects of cadmium poisoning and other background on Gold Peak click here). (socialistworld.net)
- To protect the community from the effects of cadmium contamination of the food supply, the Australia New Zealand Food Standards Code has established maximum limits on cadmium in commonly consumed food commodities (Standard 1.4.1 Contaminants and Natural Toxicants, Australia New Zealand Food Standards Code). (sa.gov.au)
- Once diagnosed, the dangerous effects of cadmium toxicity an be minimized by avoiding or removing the source of exposure as quickly as possible and ensuring the affected person is informed of ways to lessen the risk of exposure in the future. (labtestfromhome.com)
Exposure46
- Cadmium is a naturally occurring toxic metal with common exposure in industrial workplaces, plant soils, and from smoking. (wikipedia.org)
- Due to its low permissible exposure in humans, overexposure may occur even in situations where trace quantities of cadmium are found. (wikipedia.org)
- Acute exposure to cadmium fumes may cause flu-like symptoms including chills, fever, and muscle ache sometimes referred to as "the cadmium blues. (wikipedia.org)
- Cadmium exposure increases one's chances of developing cancer. (wikipedia.org)
- Similar to zinc, long-term exposure to cadmium fumes can cause lifelong anosmia. (wikipedia.org)
- citation needed] Spinal and leg pain is common, and a waddling gait often develops due to bone deformities caused by the long-term cadmium exposure. (wikipedia.org)
- Cadmium exposure is also associated with the development of kidney stones. (wikipedia.org)
- citation needed] Smoking is a significant source of cadmium exposure. (wikipedia.org)
- Environmental exposure to cadmium has been particularly problematic in Japan where many people have consumed rice that was grown in cadmium-contaminated irrigation water. (wikipedia.org)
- People who live near hazardous waste sites or factories that release cadmium into the air have the potential for exposure to cadmium in air. (wikipedia.org)
- 1984. Human health effects of exposure to cadmium. (cdc.gov)
- 2000). "Neurobehavioral effects of occupational exposure to cadmium: a cross sectional epidemiological study. (cdc.gov)
- 2003). "Occupational exposure to heavy metals: DNA damage induction and DNA repair inhibition prove co-exposures to cadmium, cobalt and lead as more dangerous than hitherto expected. (cdc.gov)
- 1992. A dose-response analysis and quantitative assessment of lung cancer risk and occupational cadmium exposure. (cdc.gov)
- Background and objective: Long-term exposure to cadmium (Cd) causes renal dysfunction, but the change in renal function with exposure is unknown. (nih.gov)
- The data, in addition to pinpointing another mechanism for some of cadmium's effects, should also impact regulatory standards for cadmium exposure. (medscape.com)
- After the long-term exposure to cadmium chloride in drinking water, the Wistar rats developed peripheral polyneuropathy. (nih.gov)
- DO NOT use it to treat or manage an actual poison exposure. (medlineplus.gov)
- If you or someone you are with has an exposure, call the local emergency number (such as 911), or the local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. (medlineplus.gov)
- Respiratory irritation and systemic poisoning from exposure to toxic fumes and particles during welding and cutting operations. (osha.gov)
- 1. Metabolic effects of long-term cadmium exposure: an overview. (nih.gov)
- 3. Metabolomic biomarkers in urine of rats following long-term low-dose exposure of cadmium and/or chlorpyrifos. (nih.gov)
- 5. Environmental cadmium exposure induces alterations in the urinary metabolic profile of pregnant women. (nih.gov)
- Application to Mus musculus mice under arsenic/cadmium exposure. (nih.gov)
- 10. Identifying early urinary metabolic changes with long-term environmental exposure to cadmium by mass-spectrometry-based metabolomics. (nih.gov)
- 11. Biochemical and metabolic responses of the deep-sea mussel Bathymodiolus platifrons to cadmium and copper exposure. (nih.gov)
- 14. Effects of long-term cadmium exposure on urinary metabolite profiles in mice. (nih.gov)
- 15. Metabolic profiling detects early effects of environmental and lifestyle exposure to cadmium in a human population. (nih.gov)
- 17. Long-term environmental cadmium exposure induced serum metabolic changes related to renal and liver dysfunctions in a female cohort from Southwest China. (nih.gov)
- 18. Metabolomic analysis of the toxic effect of chronic exposure of cadmium on rat urine. (nih.gov)
- The Agency for Toxic Substances and Disease Registry estimates that about 300,000 workers in the U.S. face exposure to cadmium each year. (cbia.com)
- The cadmium advisor is primarily intended for use by experienced medical professionals who assess workers' cadmium exposure. (cbia.com)
- It may also be useful as an educational tool for workers and members of the general public by providing information on what constitutes overexposure to cadmium and what to do to prevent exposure on the job. (cbia.com)
- If you don't know, trust me, it's really important, and as such, this little bit of cadmium that comes along for the ride, becomes a lot of potential cadmium exposure. (rsc.org)
- Add that to other avenues of exposure, like mines and metal processing along with the ease of cadmium uptake by agricultural crops, and we really are lucky our bodies have developed a system to attenuate the cadmium exposure in our diets. (rsc.org)
- More than 400 workers at Gold Peak's three China-based factories are suffering from high levels of exposure to the cancer-causing chemical cadmium, as a result of handling the chemical without protective clothing or proper safety instruction. (socialistworld.net)
- Occupations potentially at risk of cadmium exposure include those involved in the refining zinc and lead ores, iron production, cement manufacture and industries involving fossil fuel combustion, all of which can release airborne cadmium. (sa.gov.au)
- Cadmium exposure from drinking ground water and ingestion of surface soils is relatively unimportant compared with exposure from the diet - with exceptions for localised point sources of cadmium contamination in the community. (sa.gov.au)
- But, exposure to cadmium for a long time, even in small amounts, can be dangerous as it accumulates in the body. (theconversation.com)
- Europe's decision was based on research that showed even though cadmium exposure in adult non-smokers in the region is still below WHO's upper limit, exposure through food in children reaches twice the safe limit. (theconversation.com)
- Exposure to excessive cadmium through food has a significant effect on kidney health , disrupting reabsorption (such as the reabsorption of protein salt the body still needs) in the kidney's filtering unit. (theconversation.com)
- Apart from food, cadmium exposure through air is known to increase cancer risk , causing shortness of breath, lung irritation and mucous membrane damage . (theconversation.com)
- Cadmium exposure through the air in daily life, for example, occurs through cigarette smoke . (theconversation.com)
- Poisoning occurring after exposure to cadmium compounds or fumes. (nih.gov)
- People breathing in secondhand smoke also take in a higher amount of cadmium, as this is a form of environmental exposure. (labtestfromhome.com)
- According to the Agency for Toxic Substances and Disease Registry, foods account for more than 90 percent of human exposure to cadmium. (danschultzfineart.com)
Arsenic6
- Though we may honor our bodily temples with nourishing foods, we cannot realize our full health potential so long as we remain waste dumps for mercury, aluminum, cadmium, arsenic, lead and nickel. (westonaprice.org)
- Out of 275 substances on the 2007 list, arsenic is number one, lead two, mercury three and cadmium seven. (westonaprice.org)
- 2 Aluminum, cadmium, lead, cobalt and arsenic and other metals are rarely absent from such patients. (westonaprice.org)
- If we compare it to other harmful heavy metals like arsenic , cadmium may not seem to be that bad. (theconversation.com)
- Toxic heavy metals such as arsenic, lead, cadmium and mercury can enter the environment - that is, in the air around us - and, as a result, our bodies. (cerascreen.ie)
- Despite being chock-full of dangerous pollutants like mercury, arsenic (a known carcinogen), lead, selenium and cadmium, utility corporations store it all over the country in massive, unlined pits. (earthjustice.org)
Amount of cadmium6
- However, numerous state and federal regulations in the United States control the amount of cadmium that can be released to the air from waste sites and incinerators so that properly regulated sites are not hazardous. (wikipedia.org)
- The amount of cadmium content in cocoa beans depends on the location and soil conditions where the chocolate plant is grown and type of chocolate plant itself. (theconversation.com)
- This is why the European Commission last year decreased the safety threshold of the amount of cadmium in processed chocolate in the region. (theconversation.com)
- But because chocolate is often consumed by people of all ages, including children, its amount of cadmium must be regulated. (theconversation.com)
- WHO only has a limit on the amount of cadmium for dried cacao beans - 0.3 milligrams per kg . (theconversation.com)
- The chemicals within cigarettes contain cadmium, and smokers are believed to ingest twice the daily amount of cadmium as non-smokers. (labtestfromhome.com)
Toxic16
- Even small amounts of cadmium from smoking are highly toxic to humans, as the lungs absorb cadmium more efficiently than the stomach. (wikipedia.org)
- 34-year-old David Xu has been charged with attempted murder of a female colleague by lacing her water and food with the toxic metal cadmium. (foxnews.com)
- A chemical engineer in Northern California was arrested last week on attempted murder charges after allegedly poisoning his coworker's water and food with toxic metal cadmium over several years, according to court records. (foxnews.com)
- Later testing of the bottle and all three victims revealed the presence of cadmium, a toxic metal. (foxnews.com)
- Cadmium is a toxic environmental pollutant that has worrisome estrogenic effects in cell culture. (medscape.com)
- Cadmium exerts toxic effects on the kidney, the skeletal system and the respiratory system and is classified as a human carcinogen. (sa.gov.au)
- A district court judge had previously ruled that the case should be litigated in Peru…The lawsuit accuses Oxy of causing severe injuries by knowingly dumping a daily average of 850,000 barrels of toxic wastewater into the tropical rainforest inhabited by the indigenous Achuar people of northern Peru over a 30-year period…The plaintiffs allege that these outdated practices caused widespread lead and cadmium poisoning, among other health impacts. (business-humanrights.org)
- Overview of Poisoning Poisoning is the harmful effect that occurs when a toxic substance is swallowed, is inhaled, or comes in contact with the skin, eyes, or mucous membranes, such as those of the mouth or nose. (msdmanuals.com)
- Cadmium is a toxic heavy metal that serves no health-supporting function when present in the bod y. (labtestfromhome.com)
- Workers can be exposed to high cadmium levels and experience its toxic effects over time while smelting and mining for other metals. (labtestfromhome.com)
- Because the toxic metals can accumulate in our bodies, trigger heavy metal poisoning and various diseases. (cerascreen.ie)
- Poison Plastic: The Toxic. (ecocenter.org)
- Toxic metals such as lead , cadmium, and organotins are used as stabilizers. (ecocenter.org)
- Is Cadmium Paint Toxic? (danschultzfineart.com)
- We know cadmium is toxic. (danschultzfineart.com)
- Lead and cadmium are highly toxic and have both acute and chronic effects on human health and the environment. (ac.ir)
Zinc8
- The primary source for cadmium is as a byproduct of refining zinc metal. (wikipedia.org)
- 29 CFR 1910.252(c)(5) through (10) covers welding operations where workers may be exposed to fluorine compounds, zinc, lead, beryllium, cadmium, and mercury. (osha.gov)
- Cadmium sits right below zinc on the periodic table and therefore shares many of its same chemical properties. (rsc.org)
- In the environment it is distributed nearly everywhere we find zinc and therefore when we mine zinc, we consequently mine cadmium. (rsc.org)
- When we galvanize (zinc treat) a nail or some other bit of steel, a little cadmium comes along for the ride. (rsc.org)
- And finally in nature, a group at Princeton University a few years back showed that some marine diatons can substitute cadmium for zinc in the important enzyme carbonic anhydrase. (rsc.org)
- Cadmium is typically found in with other metals, and is commercially produced as a by-product of zinc and lead smelting, which act as point sources of environmental contamination of the soil, air and water in the surrounding regions. (sa.gov.au)
- Lead will replace calcium, for example, cadmium will replace zinc, and aluminum and nickel will replace magnesium and manganese. (westonaprice.org)
Cases of cadmium2
- In extreme cases of cadmium poisoning, mere body weight causes a fracture. (wikipedia.org)
- Some of the earliest cases of cadmium poisoning were reported in Belgium in 1858. (danschultzfineart.com)
Grown in cadmium-contaminated1
- There, rice grown in cadmium contaminated soils had more than 10 times the cadmium content than normal rice. (rsc.org)
Kidneys5
- The human body can only get rid of cadmium slowly and this can result in a build-up of cadmium in the body primarily in the kidneys and the liver. (sa.gov.au)
- Shellfish accumulate relatively high levels of cadmium and animal liver and kidneys can have high levels of cadmium. (sa.gov.au)
- But behind its delicious taste, cacao contains cadmium, a chemical substance harmful to kidneys . (theconversation.com)
- Ingested cadmium is usually stored in the liver, kidneys, and bones. (labtestfromhome.com)
- In vertebrate organisms, lead accumulates mainly in bones and teeth [19], and cadmium - in the liver and kidneys, but can be found in all organs [20]. (ac.ir)
Biological Monitoring Advisor2
Chronic cadmium1
- Chronic cadmium poisoning can cause kidney damage and cancer of the lung or prostate. (cbia.com)
Excessive cadmium1
- The disease results from excessive cadmium poisoning and was first reported in a small town about 200 miles north west of Tokyo. (rsc.org)
Accumulate3
- It is amazing to think that cadmium was able to accumulate to such high levels that it could overwhelm the human body's already intense defenses against it. (rsc.org)
- Many plants, including food plants, readily accumulate cadmium from the soil. (sa.gov.au)
- Lead and cadmium are cumulative poisons and accumulate in soil, water, plants and other living organisms. (ac.ir)
Risk of cadmium1
- The risk of cadmium toxicity is particularly high in workplaces manufacturing batteries, plastic, coatings, and solar panels. (labtestfromhome.com)
Toxicity of cadmium3
- Only now are the biological mechanisms for the toxicity of cadmium and other heavy metals coming to light, with studies implicating cadmium as a kidney toxin and, recently, as an inhibitor of DNA mismatch repair in yeast [ 1 ] . (medscape.com)
- As I've researched this, there seems to be some misinformation regarding the toxicity of cadmium in artist paints. (danschultzfineart.com)
- When I visited the M. Graham & Co. factory in 2015, I asked specifically about the toxicity of cadmium colors. (danschultzfineart.com)
Presence of cadmium1
- A small study of premium dark chocolate samples found 48% had high levels of cadmium, the source commonly being the presence of cadmium in soil in which they were grown. (wikipedia.org)
Concentration of cadmium3
- citation needed] Some sources of phosphate in fertilizers contain cadmium in amounts of up to 100 mg/kg, which can lead to an increase in the concentration of cadmium in soil (for example in New Zealand). (wikipedia.org)
- Cigarette smoking can cause significant increases in the concentration of cadmium in the kidney, the main target organ for cadmium toxicity. (sa.gov.au)
- ANSA) - Milan, March 18 - A Moroccan model and key prosecution witness in a Ruby-Berlusconi witness tampering trial had a high concentration of cadmium and antimony in her blood when she died after saying she had been poisoned, Milan prosecutor Francesco Greco told a press conference Monday. (ansa.it)
Blood cadmium1
- The blood cadmium (BCd) level was higher in marijuana users, independent of the frequency of use. (labtestfromhome.com)
Nickel-cadmium3
- Nickel-cadmium batteries show promise through higher efficiencies which will demonstrate their importance in the next generation of electric vehicles. (rsc.org)
- Batteries - widely used in nickel-cadmium rechargeable batteries. (labtestfromhome.com)
- About three quarters of the U.S. output is used in the production of rechargeable Nickel-Cadmium (Ni-Cad) batteries. (danschultzfineart.com)
Liver1
- 2. Screening and validation of biomarkers for cadmium-induced liver injury based on targeted bile acid metabolomics. (nih.gov)
Selenium7
- 13. Metabolic impairments, metal traffic, and dyshomeostasis caused by the antagonistic interaction of cadmium and selenium using organic and inorganic mass spectrometry. (nih.gov)
- Cadmium reduces selenium levels, which has a host of knock on effects and thus selenium in the diet should help to counter the effects of this toxicity. (allaboutheaven.org)
- Four endoplasmic reticulum resident selenoproteins may be related to the protection of selenium against cadmium toxicity in chicken lymphocytes. (allaboutheaven.org)
- In the present study, we investigated the effect of Cadmium on messenger RNA expressions of endoplasmic reticulum resident selenoproteins, selenoprotein K, selenoprotein N, selenoprotein S, and selenoprotein T, in cultured chicken lymphocytes and the antagonistic effect of Selenium. (allaboutheaven.org)
- Chicken splenic lymphocytes were treated with 10(-7) mol/L Selenium, 10(-6) mol/L Cadmium, and the mixture of 10(-6) mol/L Selenium and 10(-7) mol/L Cadmium in the culture medium for 12, 24, 36, and 48 h, respectively. (allaboutheaven.org)
- The results indicated that Selenium significantly increased the expressions of selenoprotein K, selenoprotein N, selenoprotein S, and selenoprotein T, which were reduced by Cadmium in chicken splenic lymphocytes. (allaboutheaven.org)
- Selenium reserved the protective role by increasing the expressions of selenoprotein K, selenoprotein N, selenoprotein S, and selenoprotein T. The present study provided a useful clue to investigate the possible pathogenesis of Cadmium toxicity. (allaboutheaven.org)
Chloride induced1
- Cadmium chloride induced several well-characterized estrogenic responses, including increased uterine weights, hyperplasia and hypertrophy of the endometrial lining, induction of uterine progesterone receptor and complement C3 gene expression, increased mammary epithelial density and induction of milk protein synthesis in the mammary gland. (medscape.com)
Paints4
- Cadmium is also found in some industrial paints and may represent a hazard when sprayed. (wikipedia.org)
- Operations involving removal of cadmium paints by scraping or blasting may pose a significant hazard. (wikipedia.org)
- To give cadmium its fair shake, you should know some of the most brilliant colours and paints result from cadmium salts and artists have taken advantage of these for years. (rsc.org)
- Cadmium is also utilized in production of batteries, and is contained in spray paints and cutting cadmium and its ores. (labtestfromhome.com)
Itai-itai di1
- In the present study, to evaluate chronic Cd hepatotoxicity, we examined specimens from cases of itai-itai disease, the most severe form of chronic Cd poisoning. (nih.gov)
Levels15
- Buildup of cadmium levels in the water, air, and soil has been occurring particularly in industrial areas. (wikipedia.org)
- Serum cadmium levels at delivery were measured in a consecutive sample of 100 mother-infant pairs in Egypt using venous blood from mothers and umbilical cord blood from neonates. (who.int)
- Breathing high levels of cadmium damages people's lungs and can cause death. (foxnews.com)
- OSHA Standards - Cadmium - includes a full description of required monitoring and actions required at different cadmium levels. (cdc.gov)
- Later studies showed that these women suffered from high levels of cadmium poisoning because of effluent from an upstream mine. (medscape.com)
- 16. Urine metabolomics of women from small villages exposed to high environmental cadmium levels. (nih.gov)
- As chinaworker.org reported yesterday, 200 workers turning up for their annual health check-up (to monitor cadmium poisoning levels in their body) were told by management to undress and shower - in order to leave a urine sample! (socialistworld.net)
- Campaigners attending the Hong Kong anti-WTO week of action received more shocking news: that more than 30 workers at Gold Peak's Hong Kong factory have also been diagnosed with high levels of cadmium. (socialistworld.net)
- They also revealed dangerous levels of cadmium poisoning in the sheikh. (ihrc.org.uk)
- Cadmium levels in processed chocolate on the market vary depending on the production process and the producers. (theconversation.com)
- A 2010 study on cadmium levels in chocolate powder from various countries showed chocolate powder from Venezuela was up to 1.8 milligrams per kilogram of powder . (theconversation.com)
- Mixing cocoa beans from several sources, for example, can reduce the levels of cadmium in processed chocolate. (theconversation.com)
- Greco said that tests on biological liquids had shown above-normal levels of antimony and cadmium, and the prosecutors were awaiting definitive autopsy results. (ansa.it)
- The antimony levels were almost three times normal and the cadmium was almost seven times higher than the normal range, Greco said. (ansa.it)
- Sudden high levels of cadmium in soil can cause some crops to uptake the heavy metal. (labtestfromhome.com)
Lead Poisoning3
- It hs been suggested that lead-poisoning deteriorated the population of the later Roman Empire, others have maintained that the carbonate deposits found inside Roman water pipes protected the water from lead-pickup. (atrium-media.com)
- I too have long been bothered by the reductionist arguments that lead poisoning (or 'X' or 'Y') 'caused' the fall of the Roman empire--as if it would have lasted indefinitely otherwise. (atrium-media.com)
- For comparison, we could check with remains from the British pottery industry, which was already taking lead poisoning seriously by the time of Enc Brit 11 (s.v.lead). (atrium-media.com)
Lung4
- 1992. Determinants of lung cancer risk among cadmium-exposed workers. (cdc.gov)
- Lung cancer mortality in a cohort of workers employed at a cadmium recovery plant in the United States: an analysis with detailed job histories. (cdc.gov)
- Cadmium causes acute and chronic lung disease and chronic systemic disease. (osha.gov)
- During the first five-year funding period (1987 - 1992), 10 states received SENSOR funding for experimental case-based target conditions which included elevated blood lead, carpal tunnel syndrome, pesticide poisoning, occupational lung diseases (silicosis, work-related asthma and hypersensitivity pneumonitis), and work-related burns. (nih.gov)
Exposures1
- Exposures to cadmium are addressed in specific standards for the general industry, shipyard employment, the construction industry, and the agricultural industry. (wikipedia.org)
Kidney damage2
- citation needed] The kidney damage inflicted by cadmium poisoning is irreversible. (wikipedia.org)
- Large amounts of cadmium are linked to kidney damage, cancer, and bone fractures. (labtestfromhome.com)
Environmental2
Control Centers2
- American Association of Poison Control Centers (1-800-222-1222 or www.aapcc.org/ ) .The Poison Control Center may be contacted for questions about poisons and poisonings. (cdc.gov)
- All local poison control centers in the United States use this national number. (medlineplus.gov)
19772
- No Cadmium Poison Cases in 1977! (akincana.net)
- One of the single most convincing pieces of history that confirms how the P-Con can't possibly be true is the simple fact that doctors were only beginning to understand how cadmium impacted the body in 1977. (akincana.net)
Overexposure1
- Cadmium is used extensively in electroplating, although the nature of the operation does not generally lead to overexposure. (wikipedia.org)
Urinary1
- In former users, the urinary cadmium (UCd) level was higher in those with high frequency of past use. (labtestfromhome.com)
19952
- 1995. Mortality of inhabitants in an area polluted by cadmium: 15-year follow up. (cdc.gov)
- A Russian banker, Ivan Kivelidi, died of cadmium poisoning in 1995. (chicagotribune.com)
Symptoms4
- As well as chronic systemic poisoning, welding on cadmium-coated steel can cause an acute intoxication without warning symptoms. (osha.gov)
- Fish and Shellfish Poisoning Certain types of fresh or frozen fish or shellfish may contain toxins that can cause a variety of symptoms. (msdmanuals.com)
- While cadmium intake in small amounts has negligible effects and doesn't result in any noticeable symptoms, moderate to high amounts of cadmium toxicity can be revealed with testing and can cause some severe health issues. (labtestfromhome.com)
- Find out about how heavy metals get into the environment and the human body, about heavy metal poisoning symptoms and causes and how you can treat heavy metal poising - for example, through chelation therapy . (cerascreen.ie)
Rechargeable batteries1
- The primary use of cadmium is in the manufacturing of NiCd rechargeable batteries. (wikipedia.org)
Naturally3
- The tobacco plant naturally accumulates relatively high concentrations of cadmium from the soil in its leaves. (sa.gov.au)
- Eliminating cadmium absorption naturally is a slow process, and cadmium can last for decades in the human body. (labtestfromhome.com)
- Cadmium is found naturally in the earth's crust but is a relatively rare metal. (danschultzfineart.com)
Humans2
Micrograms1
- On average, people consume about 30 micrograms of cadmium daily through a normal diet, absorbing 1 to 3 micrograms. (danschultzfineart.com)
Occurs2
- Solder poisoning occurs when someone swallows solder in large amounts. (medlineplus.gov)
- The poisoning occurs after ingesting poisonous species of mushrooms or plants or contaminated fish or shellfish. (msdmanuals.com)
Pigments2
- Other occupations include the manufacture of paint pigments, cadmium-nickel batteries and electroplating. (sa.gov.au)
- The same advice applies if you work at all with dry cadmium or other pigments. (danschultzfineart.com)
Amounts1
- When eaten, large amounts of cadmium can severely irritate the stomach and cause vomiting and diarrhea," the agency states. (foxnews.com)
Toxicological1
- 1986. Cadmium and health: a toxicological and epidemiological appraisal. (cdc.gov)
Hepatotoxicity2
- 4. Metabolomic analysis for combined hepatotoxicity of chlorpyrifos and cadmium in rats. (nih.gov)
- Amin A, Hamza A, Daoud S (2006) Spirulina protects against cadmium-induced hepatotoxicity in rats. (springer.com)
Intake3
- The daily intake of cadmium through food varies by geographic region. (wikipedia.org)
- Each metallothionein enzyme can sequester up to seven cadmium ions providing a fairly nice buffer against high cadmium intake. (rsc.org)
- Cadmium intake through contaminated foods or even tobacco smoking can lead to all kinds of problems, some even worse than the ouch-ouch disease. (rsc.org)
Soil3
- Cadmium can be removed from soil using nanopolymers. (wikipedia.org)
- Cadmium is found in fertilizer and sewage sludge which comes from contaminating agricultural soil. (labtestfromhome.com)
- The rate of cadmium absorption depends on a whole host of factors, like the crop species, the quality of the soil (pH and salinity), and the presence of other elements. (labtestfromhome.com)
Carcinogen1
- ESOH IssuesCd is a heavy metal cumulative poison and a probable (Class B1) carcinogen. (serdp-estcp.org)
Metallothionein1
- As cadmium gets absorbed by the human body it stimulates the production of the enzyme metallothionein which has an abundance of sulfide containing amino acids. (rsc.org)
Impacts1
- Marijuana use also impacts cadmium toxicity. (labtestfromhome.com)
Irritate1
- Burning fossil fuels releases cadmium to the air, and breathing it in can irritate the lungs. (labtestfromhome.com)
Occur2
- Cadmium poisoning can also occur in certain workplaces where cadmium is either used in the process or generated as a byproduct. (labtestfromhome.com)
- How does heavy metal poisoning occur? (cerascreen.ie)
Bones1
- Excess cadmium began to interfere with calcium deposition in bones. (rsc.org)
High2
- Cadmium poisoning is caused by high concentrations of cadmium accumulating in your body. (labtestfromhome.com)
- Which may explain the high price tag on cadmium paint colors! (danschultzfineart.com)
Heavy6
- Cadmium (Cd) is a highly hepatotoxic heavy metal, which is widely dispersed in the environment. (nih.gov)
- What has been missing is solid evidence that cadmium or other heavy metals have estrogenic effects in the whole animal. (medscape.com)
- What is heavy metal poisoning - why does it happen? (cerascreen.ie)
- What are heavy metals and what is heavy metal poisoning? (cerascreen.ie)
- However, both share many properties with heavy metals and can lead to poisoning in similar ways. (cerascreen.ie)
- This can introduce heavy metals like cadmium into the watershed, possibly creating problems downstream. (danschultzfineart.com)
Rats4
- New data from rats show that cadmium can act as an estrogen mimic in the whole animal, inducing conditions ranging from uterine hyperplasia to early onset of puberty. (medscape.com)
- In this issue, Martin and colleagues provide evidence in rats that cadmium acts as an estrogen mimic that can adversely affect estrogen-responsive tissues such as the uterus and mammary glands [ 2 ] . (medscape.com)
- The paper by Martin and coworkers [ 1 ] should satisfy even the most skeptical among us with their finding that cadmium chloride is a potent estrogen mimic in female rats, at doses as low as 5-10 µg/kg (single intraperitoneal injection). (medscape.com)
- 9. Identification of metabolite biomarkers in serum of rats exposed to chlorpyrifos and cadmium. (nih.gov)
Commonly1
- Children today are commonly born with cadmium toxicity passed from mother to child via the placenta. (labtestfromhome.com)
Intoxication1
- 1979. Subacute cadmium intoxication in jewelry workers: an evaluation of diagnostic procedures. (cdc.gov)