'Anus diseases' refer to various medical conditions affecting the anus, including structural abnormalities, inflammatory disorders, infections, and neoplasms, which can cause symptoms such as pain, bleeding, itching, or changes in bowel habits.
A congenital abnormality characterized by the persistence of the anal membrane, resulting in a thin membrane covering the normal ANAL CANAL. Imperforation is not always complete and is treated by surgery in infancy. This defect is often associated with NEURAL TUBE DEFECTS; MENTAL RETARDATION; and DOWN SYNDROME.
Tumors or cancer of the ANAL CANAL.
The terminal segment of the LARGE INTESTINE, beginning from the ampulla of the RECTUM and ending at the anus.
An abnormal anatomical passage between the RECTUM and the VAGINA.
The body region lying between the genital area and the ANUS on the surface of the trunk, and to the shallow compartment lying deep to this area that is inferior to the PELVIC DIAPHRAGM. The surface area is between the VULVA and the anus in the female, and between the SCROTUM and the anus in the male.
An abnormal anatomical passage connecting the RECTUM to the outside, with an orifice at the site of drainage.
Abortion performed because of possible fetal defects.
Congenital structural abnormalities of the UROGENITAL SYSTEM in either the male or the female.
The distal segment of the LARGE INTESTINE, between the SIGMOID COLON and the ANAL CANAL.
Protrusion of the rectal mucous membrane through the anus. There are various degrees: incomplete with no displacement of the anal sphincter muscle; complete with displacement of the anal sphincter muscle; complete with no displacement of the anal sphincter muscle but with herniation of the bowel; and internal complete with rectosigmoid or upper rectum intussusception into the lower rectum.
'Abnormalities, Multiple' is a broad term referring to the presence of two or more structural or functional anomalies in an individual, which may be genetic or environmental in origin, and can affect various systems and organs of the body.
A dilated cavity extended caudally from the hindgut. In adult birds, reptiles, amphibians, and many fishes but few mammals, cloaca is a common chamber into which the digestive, urinary and reproductive tracts discharge their contents. In most mammals, cloaca gives rise to LARGE INTESTINE; URINARY BLADDER; and GENITALIA.
Pathological developments in the RECTUM region of the large intestine (INTESTINE, LARGE).
Swollen veins in the lower part of the RECTUM or ANUS. Hemorrhoids can be inside the anus (internal), under the skin around the anus (external), or protruding from inside to outside of the anus. People with hemorrhoids may or may not exhibit symptoms which include bleeding, itching, and pain.
An intravenous anesthetic that has been used for rapid induction of anesthesia and for maintenance of anesthesia of short duration. (From Martindale, The Extra Pharmacopoeia, 30th ed, p918)
Organs or parts of organs surgically formed from nearby tissue to function as substitutes for diseased or surgically removed tissue.
The act of dilating.
Congenital structural abnormalities of the DIGESTIVE SYSTEM.
An abnormal passage in any part of the URINARY TRACT between itself or with other organs.
A birth defect in which the URINARY BLADDER is malformed and exposed, inside out, and protruded through the ABDOMINAL WALL. It is caused by closure defects involving the top front surface of the bladder, as well as the lower abdominal wall; SKIN; MUSCLES; and the pubic bone.
The surgical construction of an opening between the colon and the surface of the body.

Risk factors for abnormal anal cytology in young heterosexual women. (1/213)

Although anal cancers are up to four times more common in women than men, little is known about the natural history of anal human papillomavirus (HPV) infections and HPV-related anal lesions in women. This study reports on the prevalence of and risks for anal cytological abnormalities over a 1-year period in a cohort of young women participating in a study of the natural history of cervical HPV infection. In addition to their regularly scheduled sexual behavior interviews and cervical testing, consenting women received anal HPV DNA and cytological testing. Anal cytology smears were obtained from 410 women whose mean age was 22.5 +/- 2.5 years at the onset of the study. Sixteen women (3.9%) were found to have abnormal anal cytology: 4 women had low-grade squamous intraepithelial lesions (SILs) or condyloma; and 12 women had atypical cells of undetermined significance. Factors found to be significantly associated with abnormal anal cytology were a history of anal sex [odds ratio (OR), 6.90; 95% confidence interval (CI), 1.7-47.2], a history of cervical SILs (OR, 4.13; 95% CI, 1.3-14.9), and a current anal HPV infection (OR, 12.28; 95% CI, 3.9-43.5). The strong association between anal intercourse and the development of HPV-induced SILs supports the role of sexual transmission of HPV in anal SILs. Young women who had engaged in anal intercourse or had a history of cervical SILs were found to be at highest risk.  (+info)

Tissue specific HPV expression and downregulation of local immune responses in condylomas from HIV seropositive individuals. (2/213)

OBJECTIVE: To study the effect of tissue specific human papillomavirus (HPV) expression and its effect on local immunity in condylomas from HIV positive individuals. METHODS: Biopsy specimens of eight penile and eight perianal condylomas from HIV seropositive individuals were analysed. Expression of viral genes (HIV-tat and HPV E7 and L1) was determined by RT-PCR. The status of local immunity also was determined by RT-PCR by measuring CD4, CD8, CD16, CD1a, HLA-DR, and HLA-B7 mRNA levels in the tissues. Differentiation was determined by measuring involucrin, keratinocyte transglutaminase, as well as cytokeratins 10, 16, and 17. Proliferation markers such as PCNA and c-myc were also determined. RESULTS: The transcription pattern of HPV in perianal condylomas, which preferentially expressed the early (E7) gene, was different from that of penile condylomas, which primarily expressed the late (L1) gene. This transcription pattern is in good correlation with the keratinisation and differentiation patterns of the two epithelia: perianal biopsies preferentially expressed K16 and K17 while penile warts mainly expressed K10, markers of parakeratotic and orthokeratotic epithelia, respectively. Perianal biopsies also showed a higher degree of proliferation (PCNA and c-myc). Interestingly, transcription of HIV-tat was also higher in perianal than in penile biopsies. A high degree of local immunodeficiency was observed in perianal biopsies--that is, levels of CD4, CD16, and CD1a mRNAs were significantly lower. A negative correlation between CD1a (Langerhans cells) levels and HPV E7 levels was established. HPV E7 levels positively correlated with HIV-tat levels. Perianal tissues demonstrated more CD1a depression and tat associated HPV upregulation. CONCLUSION: HIV influences the expression of HPV genes resulting in local immunosuppression that might lead to an inappropriate immune surveillance of viral infection. Also, tissue type is an important factor in controlling viral transcription in a differentiation dependent manner. These findings may explain the higher rate of dysplasia and neoplasia in the perianal area.  (+info)

Susceptibility of gonococci isolated in London to therapeutic antibiotics: establishment of a London surveillance programme. London Gonococcal Working Group. (3/213)

OBJECTIVES: To establish the in vitro susceptibility of gonococci isolated in the London area to antibiotics in current therapeutic use and to establish a sentinel surveillance system for monitoring trends in antibiotic resistant gonorrhoea in London. METHODS: Isolates of Neisseria gonorrhoeae from consecutive patients attending genitourinary medicine clinics at 10 hospitals in the London area were collected over a 3 month period, May to July 1997. The susceptibility to penicillin, ciprofloxacin, tetracycline, and spectinomycin was determined for each isolate. Isolates exhibiting either plasmid or chromosomally mediated resistance were additionally tested for susceptibility to agents used as alternative treatments including azithromycin, ceftriazone, and ofloxacin. The resistant isolates were also tested for plasmid profiles (penicillinase producing N gonorrhoeae, PPNG), type of tetM determinant (tetracycline resistant N gonorrhoeae, TRNG), and presence of gyrA and parC mutations (quinolone resistant N gonorrhoeae, QRNG). RESULTS: A total of 1133 isolates were collected which represents > 95% of the total gonococci isolated in the 3 months. Plasmid mediated resistance was exhibited by 48 (4.2%) isolates; six (0.5%) were PPNG, 15 (1.3%) were PP/TRNG, and 27 (2.4%) were TRNG. The majority of PPNG (18 of 20 tested) carried the 3.2 MDa penicillinase plasmid whereas the two types of tetM determinant were more evenly distributed. High level resistance to ciprofloxacin was detected in four (0.4%) isolates and double mutations were found in the quinolone resistance determining region (QRDR) of the gyrA gene in three QRNG with MICs of 16 mg/l and a single mutation in one isolate with a MIC of 1 mg/l to ciprofloxacin. No parC mutations were found. Of the remaining 1081 isolates, 86 (8.0%) were chromosomally mediated resistant N gonorrhoeae (CMRNG). CONCLUSIONS: A unique collection of gonococcal isolates has been established which can be used as a baseline for surveillance of susceptibility to antibiotics and for epidemiological purposes.  (+info)

Functional disorders of the anus and rectum. (4/213)

In this report the functional anorectal disorders, the etiology of which is currently unknown or related to the abnormal functioning of normally innervated and structurally intact muscles, are discussed. These disorders include functional fecal incontinence, functional anorectal pain, including levator ani syndrome and proctalgia fugax, and pelvic floor dyssynergia. The epidemiology of each disorder is defined and discussed, their pathophysiology is summarized and diagnostic approaches and treatment are suggested. Some suggestions for the direction of future research on these disorders are also given.  (+info)

Ileoanal anastomosis with reservoirs: complications and long-term results. (5/213)

OBJECTIVE: To determine the rate of complications of ileoanal pouch anastomosis, their treatment and their influence on a successful outcome. DESIGN: A computerized database and chart review. SETTING: Three academic tertiary care health centres. PATIENTS: All 239 patients admitted for surgery between 1981 and 1994 with a diagnosis of ulcerative colitis and familial adenomatosis coli. INTERVENTIONS: Sphincter-saving total proctocolectomy and construction of either S-type of J-type ileoanal reservoir. OUTCOME MEASURES: Indications, early and late complications, incidence of pouch excision. RESULTS: Of the 239 patients, 228 (95.4%) were operated on for ulcerative colitis and 11 (4.6%) for familial polyposis coli. One patient in each group was found to have a carcinoma not previously diagnosed. Twenty-eight patients had poor results: in 17 (7.1%) the ileostomy was never closed or was re-established because of pelvic sepsis or complex fistulas, sclerosing cholangitis or severe diarrhea; 11 (4.6%) patients required excision of the pouch because of anal stenosis, perirectal abscess-fistula or rectovaginal fistula. Three patients died--of suicide, and complications of liver transplantation and HIV infection. Thus, 208 patients maintained a functioning pouch. The early complication rate (within 30 days of operation) was 57.7% (138 patients) and the late complication rate was 52.3% (125 patients). Pouchitis alone did not lead to failure or pouch excision. Emptying difficulties in 25 patients with anal stenosis were helped in 2 by resorting to intermittent catheterization. Patients with indeterminate colitis had a higher rate of anorectal septic complications, and all patients having Crohn's disease after pouch construction had complicated courses. CONCLUSIONS: The complication rate associated with ileoanal pouch anastomosis continues to be relatively high despite increasing experience with this technique. Overall, however, a satisfactory outcome was obtained in 87% of patients.  (+info)

The clinical spectrum of Clostridium sordellii bacteraemia: two case reports and a review of the literature. (6/213)

Clostridium sordellii is rarely associated with disease in humans. Since its first report in 1922 only a few cases of bacteraemia have been reported. This report describes two cases of C sordellii bacteraemia; the oldest and youngest patients reported to date. The first, is a previously well 81 year old woman presented with perianal infection, which was later complicated by thrombosis of the aorta, and the second is a 12 year old boy with epilepsy who presented with an ear infection. These cases are also highlighted to demonstrate the wide spectrum of presentation of sordellii bacteraemia.  (+info)

Prevalence and risk factors for anal human papillomavirus infection in human immunodeficiency virus (HIV)-positive and high-risk HIV-negative women. (7/213)

Little is known about the epidemiology of anal human papillomavirus (HPV) infection in women. We studied 251 human immunodeficiency virus (HIV)-positive and 68 HIV-negative women for the presence of anal HPV by use of polymerase chain reaction (PCR) and hybrid capture. Medical and behavioral risk factors were evaluated; 76% of HIV-positive and 42% of HIV-negative women were found to have anal HPV DNA via analysis by PCR (relative risk [RR], 1.8; 95% confidence interval [CI], 1.3-2.5). Among 200 women for whom there were concurrent anal and cervical HPV data, anal HPV was more common than cervical HPV in both HIV-positive (79% vs. 53%) and HIV-negative women (43% vs. 24%). By multivariate analysis of HIV-positive women, CD4(+) cell counts 500 cells/mm(3) (RR, 1.4; 95% CI, 1.1-1.5), and cervical HPV infection (RR, 1.3; 95% CI, 1.1-1.4) were associated with anal HPV infection. Women >45 years old had reduced risk, compared with women <36 years old (RR, 0.80; 95% CI, 0.50-0.99), as did African American women (RR, 0.86; 95% CI, 0.72-1.0), compared with white women. Anal HPV infection is underrecognized in HIV-positive and high-risk HIV-negative women.  (+info)

Topical phenylephrine increases anal canal resting pressure in patients with faecal incontinence. (8/213)

INTRODUCTION: The internal anal sphincter receives a stimulatory alpha(1) adrenergic innervation. Use of an adrenergic agonist may therefore have a role in treating patients with faecal incontinence. METHODS: Ten patients (seven females, median age 66 years) with passive faecal incontinence related to weak internal anal sphincter were studied. All patients had intact anal sphincters as assessed by endoanal ultrasound. Phenylephrine gel was applied in a double blind manner in concentrations of 0%, 10%, 20%, 30%, and 40% (Slaco Pharma (UK) Ltd, Watford, UK) on separate days. Maximum resting anal pressure (MRP), anodermal blood flow, blood pressure, and pulse rate were measured before, and one and two hours after application. RESULTS: All concentrations of phenylephrine gel increased median MRP (43, 48, 54, 65, and 70 cm H(2)O, for placebo, 10% (p=0.122), 20% (p=0.170), 30% (p=0.002), and 40% (p=0.004), respectively at one hour; comparisons with placebo). This was sustained at two hours. There was a clear dose-response relationship at one hour. Higher concentrations raised median MRP to within the normal range (> 60 cm H(2)O). At two hours, all concentrations greater than 20% increased the pressure to a similar degree, suggesting that the exact concentration may be important for the initial effect but given a certain threshold is less important after a period of time. Toxicity was rare. Two patients experienced transient perianal burning which settled within a few minutes. There was no significant effect on anodermal blood flow, blood pressure, or pulse rate. CONCLUSION: This study has demonstrated the feasibility of using topical phenylephrine to raise resting anal tone in patients with faecal incontinence. Randomised controlled trials are required to assess the efficacy of this agent.  (+info)

The anus is the opening at the end of the digestive tract where feces are eliminated from the body. There are several diseases and conditions that can affect the anus, including:

1. Anal fissure: A small tear in the lining of the anus, which can cause pain and bleeding during bowel movements.
2. Hemorrhoids: Swollen veins in the rectum or anus that can cause discomfort, itching, and bleeding.
3. Perianal abscess: A collection of pus in the tissue surrounding the anus, which can cause pain, swelling, and redness.
4. Anal fistula: An abnormal connection between the anal canal and the skin around the anus, often resulting from a perianal abscess that did not heal properly.
5. Anal cancer: A rare form of cancer that develops in the cells lining the anus, usually affecting people over the age of 50.
6. Inflammatory bowel disease (IBD): A group of chronic inflammatory conditions of the intestine, including Crohn's disease and ulcerative colitis, which can affect the anus and cause symptoms such as pain, bleeding, and diarrhea.
7. Sexually transmitted infections (STIs): Certain STIs, such as herpes simplex virus, chlamydia, gonorrhea, and syphilis, can affect the anus and cause symptoms such as pain, discharge, and sores.
8. Fecal incontinence: The involuntary loss of bowel control, which can be caused by nerve damage, muscle weakness, or other medical conditions affecting the anus.

Imperforate anus is a congenital condition in which the opening of the anus is absent or abnormally closed or narrowed, preventing the normal passage of stool. This results in a blockage in the digestive tract and can lead to serious health complications if not treated promptly.

The anus is the external opening of the rectum, which is the lower end of the digestive tract. During fetal development, the rectum and anus normally connect through a canal called the anal canal or the recto-anal canal. In imperforate anus, this canal may be completely closed or narrowed, or it may not form properly.

Imperforate anus can occur as an isolated condition or as part of a genetic syndrome or other congenital abnormalities. The exact cause is not fully understood, but it is believed to result from a combination of genetic and environmental factors.

Treatment for imperforate anus typically involves surgery to create an opening in the anus and restore normal bowel function. In some cases, additional procedures may be necessary to correct related abnormalities or complications. The prognosis for individuals with imperforate anus depends on the severity of the condition and any associated abnormalities. With prompt and appropriate treatment, most people with imperforate anus can lead normal lives.

Anus neoplasms refer to abnormal growths or tumors in the anus, which is the opening at the end of the digestive tract where solid waste leaves the body. These growths can be benign (non-cancerous) or malignant (cancerous). Common types of anus neoplasms include squamous cell carcinoma, adenocarcinoma, and melanoma.

Squamous cell carcinoma is the most common type of anus cancer, accounting for about 80% of all cases. It begins in the squamous cells that line the anal canal and can spread to other parts of the body if left untreated.

Adenocarcinoma is a less common type of anus cancer that arises from glandular cells in the anus. This type of cancer is often associated with long-standing inflammatory conditions, such as anal fistulas or ulcerative colitis.

Melanoma is a rare form of skin cancer that can also occur in the anus. It develops from pigment-producing cells called melanocytes and tends to be aggressive with a high risk of spreading to other parts of the body.

Other less common types of anus neoplasms include basal cell carcinoma, sarcoma, and lymphoma. Treatment options for anus neoplasms depend on the type, stage, and location of the tumor, as well as the patient's overall health.

The anal canal is the terminal portion of the digestive tract, located between the rectum and the anus. It is a short tube-like structure that is about 1 to 1.5 inches long in adults. The main function of the anal canal is to provide a seal for the elimination of feces from the body while also preventing the leakage of intestinal contents.

The inner lining of the anal canal is called the mucosa, which is kept moist by the production of mucus. The walls of the anal canal contain specialized muscles that help control the passage of stool during bowel movements. These muscles include the internal and external sphincters, which work together to maintain continence and allow for the voluntary release of feces.

The anal canal is an important part of the digestive system and plays a critical role in maintaining bowel function and overall health.

A rectovaginal fistula is an abnormal connection or passage between the rectum (the lower end of the colon, leading to the anus) and the vagina. This type of fistula can result from various causes, such as childbirth injuries, surgery complications, Crohn's disease, radiation therapy, or infections. The condition may lead to symptoms like fecal matter passing through the vagina, recurrent vaginal infections, discomfort during sexual intercourse, and skin irritation around the vaginal area. Treatment options typically involve surgical repair of the fistula, depending on its size, location, and underlying cause.

The perineum is the region between the anus and the genitals. In anatomical terms, it refers to the diamond-shaped area located in the lower part of the pelvis and extends from the coccyx (tailbone) to the pubic symphysis, which is the joint in the front where the two pubic bones meet. This region contains various muscles that support the pelvic floor and contributes to maintaining urinary and fecal continence. The perineum can be further divided into two triangular regions: the urogenital triangle (anterior) and the anal triangle (posterior).

A rectal fistula is an abnormal connection or tunnel that develops between the rectum, which is the lower end of the colon, and another organ or the skin surface surrounding the anus. This condition often results from inflammation, infection, trauma, or surgery in the anal area. The fistula can cause symptoms such as pain, discharge, irritation, and swelling around the anus. In some cases, it may also lead to complications like abscesses or recurrent infections if not treated promptly and effectively. Treatment options typically include surgical intervention to close the fistula and promote healing of the affected tissues.

An "eugenic abortion" is not a medical term, but rather a descriptive phrase that combines two concepts: eugenics and abortion.

Eugenics refers to the belief and practice of improving the human species by encouraging reproduction of individuals with desired traits and preventing reproduction of those with undesired traits. This concept has been widely criticized for its potential to be used as a tool for discrimination and oppression.

Abortion, on the other hand, is the medical procedure to end a pregnancy before the fetus can survive outside the womb.

A "eugenic abortion," therefore, generally refers to the practice of terminating a pregnancy based on the perceived genetic traits or characteristics of the fetus, such as disability, race, or sex. This phrase is often used in discussions about the ethics and morality of selective abortions, and it raises important questions about discrimination, reproductive rights, and medical ethics. It's worth noting that the vast majority of abortions are not performed for eugenic reasons, but rather due to a variety of personal, medical, and socioeconomic factors.

Urogenital abnormalities refer to structural or functional anomalies that affect the urinary and genital systems. These two systems are closely linked during embryonic development, and sometimes they may not develop properly, leading to various types of congenital defects. Urogenital abnormalities can range from minor issues like a bifid scrotum (a condition where the scrotum is split into two parts) to more severe problems such as bladder exstrophy (where the bladder develops outside the body).

These conditions may affect urination, reproduction, and sexual function. They can also increase the risk of infections and other complications. Urogenital abnormalities can be diagnosed through physical examination, imaging tests, or genetic testing. Treatment options depend on the specific condition but may include surgery, medication, or lifestyle changes.

The rectum is the lower end of the digestive tract, located between the sigmoid colon and the anus. It serves as a storage area for feces before they are eliminated from the body. The rectum is about 12 cm long in adults and is surrounded by layers of muscle that help control defecation. The mucous membrane lining the rectum allows for the detection of stool, which triggers the reflex to have a bowel movement.

Rectal prolapse is a medical condition where the rectum, which is the lower end of the colon, slips outside the anus, the opening through which stool leaves the body. This usually occurs due to weakened muscles and supporting structures in the pelvic area, often as a result of aging, childbirth, or long-term constipation or diarrhea.

The rectal prolapse can be partial, where only a small portion of the rectum slips outside the anus, or complete, where the entire rectum protrudes. This condition can cause discomfort, pain, bleeding, and difficulty with bowel movements. Treatment options may include dietary changes, medication, or surgical intervention.

'Abnormalities, Multiple' is a broad term that refers to the presence of two or more structural or functional anomalies in an individual. These abnormalities can be present at birth (congenital) or can develop later in life (acquired). They can affect various organs and systems of the body and can vary greatly in severity and impact on a person's health and well-being.

Multiple abnormalities can occur due to genetic factors, environmental influences, or a combination of both. Chromosomal abnormalities, gene mutations, exposure to teratogens (substances that cause birth defects), and maternal infections during pregnancy are some of the common causes of multiple congenital abnormalities.

Examples of multiple congenital abnormalities include Down syndrome, Turner syndrome, and VATER/VACTERL association. Acquired multiple abnormalities can result from conditions such as trauma, infection, degenerative diseases, or cancer.

The medical evaluation and management of individuals with multiple abnormalities depend on the specific abnormalities present and their impact on the individual's health and functioning. A multidisciplinary team of healthcare professionals is often involved in the care of these individuals to address their complex needs.

A cloaca is a common cavity or channel in some animals, including many birds and reptiles, that serves as the combined endpoint for the digestive, urinary, and reproductive systems. Feces, urine, and in some cases, eggs are all expelled through this single opening. In humans and other mammals, these systems have separate openings. Anatomical anomalies can result in a human born with a cloaca, which is very rare and typically requires surgical correction.

Rectal diseases refer to conditions that affect the structure or function of the rectum, which is the lower end of the large intestine, just above the anus. The rectum serves as a storage area for stool before it is eliminated from the body. Some common rectal diseases include:

1. Hemorrhoids: Swollen veins in the rectum or anus that can cause pain, itching, bleeding, and discomfort.
2. Rectal cancer: Abnormal growth of cells in the rectum that can invade and destroy nearby tissue and spread to other parts of the body.
3. Anal fissures: Small tears in the lining of the anus that can cause pain, bleeding, and itching.
4. Rectal prolapse: A condition where the rectum slips outside the anus, causing discomfort, fecal incontinence, and other symptoms.
5. Inflammatory bowel disease (IBD): A group of chronic inflammatory conditions that affect the digestive tract, including the rectum, such as Crohn's disease and ulcerative colitis.
6. Rectal abscess: A collection of pus in the rectum caused by an infection, which can cause pain, swelling, and fever.
7. Fistula-in-ano: An abnormal connection between the rectum and the skin around the anus, which can cause drainage of pus or stool.
8. Rectal foreign bodies: Objects that are accidentally or intentionally inserted into the rectum and can cause injury, infection, or obstruction.

These are just a few examples of rectal diseases, and there are many other conditions that can affect the rectum. If you experience any symptoms related to the rectum, it is important to seek medical attention from a healthcare professional for proper diagnosis and treatment.

Hemorrhoids are swollen veins in the rectum or anus that can cause pain, itching, bleeding, and bulging. They can be internal (inside the rectum) or external (under the skin around the anus). Internal hemorrhoids may protrude through the anus and become irritated, leading to bleeding. External hemorrhoids are more likely to cause pain and swelling, especially if they become thrombosed (formed a blood clot). Hemorrhoids can be caused by straining during bowel movements, pregnancy, obesity, chronic constipation or diarrhea, aging, and sitting for long periods of time. They are often treated with over-the-counter creams, suppositories, or warm sitz baths, but severe cases may require surgical intervention.

Propofol, also known as Propanidid among other names, is a short-acting medication that belongs to a class of drugs called general anesthetics. It is used during induction and maintenance of general anesthesia, sedation for mechanically ventilated adults, and procedural sedation.

Propofol works by depressing the central nervous system and producing a state of decreased consciousness, amnesia, and muscle relaxation. It is administered intravenously and its effects begin to be felt within 30 seconds to 1 minute after injection, with an average duration of action of about 4-6 minutes.

Like all general anesthetics, propofol carries a risk of serious side effects, including respiratory depression, low blood pressure, and allergic reactions. It should only be administered by trained medical professionals in a controlled clinical setting.

"Surgically-created structures" is not a standard medical term, but I can provide a general explanation of surgical procedures that create or modify anatomical structures.

Surgical procedures may involve creating new structures or modifying existing ones to achieve specific therapeutic goals. These modifications can be temporary or permanent and are often designed to improve organ function, restore physiological processes, or correct congenital abnormalities. Here are some examples of surgically-created structures:

1. Anastomosis: The connection of two hollow organs (e.g., intestines, blood vessels) or the reconnection of severed tubular structures after resection (removal) of damaged or diseased segments. Common types include end-to-end, side-to-side, and end-to-side anastomoses.
2. Stoma: An artificial opening created between a hollow organ (e.g., intestine, bladder) and the body surface to allow for waste elimination or drainage. Examples include colostomy, ileostomy, and urostomy.
3. Fistula: An abnormal connection or passageway between two organs, vessels, or the skin and an organ. Surgical creation of a fistula can be intentional (e.g., to divert intestinal contents in the management of complex wounds) or unintentional (e.g., as a complication).
4. Shunts: Artificial channels created to redirect fluid flow between body compartments, cavities, or vessels. Examples include peritoneal dialysis catheters, ventriculoperitoneal shunts for hydrocephalus management, and portosystemic shunts in the treatment of portal hypertension.
5. Flaps: A surgical technique used to relocate tissue from one part of the body to another while maintaining its blood supply. Flaps can be created using skin, muscle, fascia, or bone and are used for various purposes, such as wound closure, soft tissue reconstruction, or coverage of vital structures.
6. Grafts: Transplantation of tissue from one site to another or from a donor to a recipient. Common types include autografts (from the same individual), allografts (from another individual of the same species), and xenografts (from a different species). Examples include skin grafts, heart valve replacements, and corneal transplants.
7. Implants: Artificial devices or materials placed within the body to replace or augment function, support structures, or deliver medication. Examples include pacemakers, cochlear implants, orthopedic prostheses, and drug-eluting stents.
8. Stomas: Surgically created openings on the body surface that allow for the passage of bodily fluids or waste. Common examples include colostomies, ileostomies, and gastrostomies.

Dilation, also known as dilatation, refers to the process of expanding or enlarging a body passage or cavity. In medical terms, it typically refers to the widening of a bodily opening or hollow organ, allowing for increased flow or access. This can occur naturally, such as during childbirth when the cervix dilates to allow for the passage of a baby, or it can be induced through medical procedures or interventions.

For example, dilation of the pupils is a natural response to darkness or certain medications, while dilation of blood vessels is a common side effect of some drugs and can also occur in response to changes in temperature or emotional state. Dilation of the stomach or intestines may be necessary for medical procedures such as endoscopies or surgeries.

It's important to note that dilation can also refer to the abnormal enlargement of a body part, such as dilated cardiomyopathy, which refers to an enlarged and weakened heart muscle.

The digestive system is a complex series of organs and glands that process food. Abnormalities in the digestive system can refer to a wide range of conditions that affect any part of the system, including the esophagus, stomach, small intestine, large intestine, liver, pancreas, and gallbladder. These abnormalities can be present at birth (congenital) or acquired later in life due to various factors such as infection, inflammation, injury, or disease.

Some examples of digestive system abnormalities include:

1. Gastroesophageal Reflux Disease (GERD): A condition where the stomach acid flows back into the esophagus, causing heartburn and damage to the esophageal lining.
2. Peptic Ulcers: Open sores that develop on the lining of the stomach or duodenum, often caused by bacterial infections or long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs).
3. Inflammatory Bowel Disease (IBD): A group of chronic inflammatory conditions of the intestine, including Crohn's disease and ulcerative colitis.
4. Irritable Bowel Syndrome (IBS): A functional gastrointestinal disorder characterized by abdominal pain, bloating, and altered bowel habits.
5. Celiac Disease: An autoimmune disorder where the ingestion of gluten leads to damage in the small intestine.
6. Diverticulosis: The presence of small pouches or sacs that form on the lining of the intestine, which can become inflamed or infected (diverticulitis).
7. Hiatal Hernia: A condition where a portion of the stomach protrudes through the diaphragm into the chest cavity.
8. Hepatitis: Inflammation of the liver, often caused by viral infections or toxins.
9. Cirrhosis: A chronic liver disease characterized by scarring and loss of liver function, often due to long-term alcohol abuse or hepatitis.
10. Gallstones: Small, hard deposits that form in the gallbladder and can cause pain and inflammation.

These are just a few examples of gastrointestinal disorders, and there are many others. If you are experiencing symptoms such as abdominal pain, bloating, diarrhea, constipation, or difficulty swallowing, it is important to speak with your healthcare provider to determine the cause and develop an appropriate treatment plan.

A urinary fistula is an abnormal connection or passage between the urinary tract and another organ or tissue, such as the bladder, ureter, or kidney, and the skin, vagina, or intestine. This condition can lead to urine leakage through the abnormal opening, causing discomfort, infection, and other complications if not treated promptly and effectively. Urinary fistulas can be caused by various factors, including surgery, injury, radiation therapy, inflammation, or cancer. The type and location of the fistula will determine the specific symptoms and treatment options.

Bladder exstrophy is a congenital birth defect that affects the urinary and reproductive systems, as well as the abdominal wall. In this condition, the bladder is not fully formed and is turned inside out and exposed on the outside of the body at birth. This results in the inability to control urination and can also lead to other complications such as infection and kidney damage if left untreated.

Bladder exstrophy occurs due to a problem with the development of the fetus during pregnancy, specifically during the formation of the lower abdominal wall. It is more common in boys than girls, and can occur on its own or as part of a spectrum of defects known as the exstrophy-epispadias complex.

Treatment for bladder exstrophy typically involves surgical reconstruction to repair the bladder and lower abdominal wall. This may be done in stages, starting with the closure of the abdominal wall and then followed by bladder reconstruction at a later time. In some cases, additional surgeries may be necessary to address other associated defects or complications. With proper treatment, most children with bladder exstrophy can lead normal lives, although they may require ongoing medical management and monitoring throughout their lives.

A colostomy is a surgical procedure that involves creating an opening, or stoma, through the abdominal wall to divert the flow of feces from the colon (large intestine) through this opening and into a pouch or bag worn outside the body. This procedure is typically performed when a portion of the colon has been removed due to disease or injury, such as cancer, inflammatory bowel disease, or trauma.

There are several types of colostomies, including end colostomy, loop colostomy, and double-barrel colostomy, which differ in terms of the location and configuration of the stoma. The type of colostomy performed will depend on the individual's medical condition and the specific goals of the surgery.

After a colostomy, patients will need to learn how to care for their stoma and manage their bowel movements using specialized equipment and techniques. With proper care and management, most people are able to lead active and fulfilling lives after a colostomy.

Of diseases of the anus. IV. Of the king's evil. V. Of wounds. VI. Of gun-shot wounds. VII. Of fractures and luxations. VIII. ... Hesiod reports an ontological conception of disease via the Pandora myth. Disease has a "life" of its own but is of divine ... Disease and Medicine in World History (2003), 166pp online Archived 26 September 2017 at the Wayback Machine Interactive ... Thus the country swarms with medical practitioners, some undertaking to cure diseases of the eye, others of the head, others ...
Of diseases of the anus. IV. Of the king's evil. V. Of wounds. VI. Of gun-shot wounds. VII. Of fractures and luxations. VIII. ... proposing that diseases have natural causes along with the Four temperaments theory of disease, and leaving the Hippocratic ... The text includes recipes, a pharmacopoeia and descriptions of numerous diseases as well as cosmetic treatments. It mentions ... Hunter greatly advanced knowledge of venereal disease and introduced many new techniques of surgery, including new methods for ...
Diseases of the Anus and Rectum. Longmans, Green & Co., 1900. Marvin L. Corman. Colon and Rectal Surgery, page 298. Lippincott ... He developed an interest in rectal surgery, writing a chapter in Diseases of the Anus and Rectum in which Goodsall's rule is ...
Diseases of the rectum and anus". In Goldman, Lee; Schafer, Andrew I. (eds.). Goldman-Cecil Medicine. Vol. 1 (26th ed.). ... Anatomy of the anus and rectum Left levator ani from within The interior of the anal canal and lower part of the rectum Median ... The anus is the aperture at the terminal portion of the anal canal. In humans, the anal canal is approximately 2.5 to 4 cm ( ... The anal canal is the part that connects the rectum to the anus, located below the level of the pelvic diaphragm. It is located ...
Diseases of the rectum and anus: perianal abscess". In Goldman, Lee; Schafer, Andrew I. (eds.). Goldman-Cecil Medicine. Vol. 1 ... "Crohn's Disease". National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Archived from the original on ... Anorectal abscess (also known as an anal/rectal abscess, or perianal/perirectal abscess) is an abscess adjacent to the anus. ... This condition may occur in isolation, but is frequently indicative of another underlying disorder, such as Crohn's disease. If ...
Diseases of the rectum and anus: anal fistula". In Goldman, Lee; Schafer, Andrew I. (eds.). Goldman-Cecil Medicine. Vol. 1 ( ... The fistula plug is positioned from the inside of the anus with suture. According to some sources, the success rate with this ... Anal fistula". J Anus Rectum Colon. 2 (3): 103-109. doi:10.23922/jarc.2018-009. PMC 6752149. PMID 31559351. Wikimedia Commons ... The grades of this classification correlate quite well with the severity of the disease. Grade I & II are simpler fistulas and ...
Goldstone, Stephen E.; Welton, Mark L. (2004). "Sexually Transmitted Diseases of the Colon, Rectum, and Anus". Clin Colon ... While the nerve endings in the anus can provide pleasurable feelings, an orgasm may be achieved through receptive anal ... Goodreau SM, Golden MR (October 2007). "Biological and demographic causes of high HIV and sexually transmitted disease ... and anus (anilingus). Wellings et al. reported that "the equation of 'homosexual' with 'anal' sex among men is common among lay ...
Goldstone, Stephen E.; Welton, Mark L. (2004). "Sexually Transmitted Diseases of the Colon, Rectum, and Anus". Clin Colon ... Anal sex or anal intercourse is generally the insertion and thrusting of the erect penis into a person's anus, or anus and ... Women may sexually stimulate a man's anus by fingering the exterior or interior areas of the anus; they may also stimulate the ... Although the anus has many nerve endings, their purpose is not specifically for inducing orgasm, and so a woman achieving ...
Other causes include Crohn's disease, radiotherapy, removal of perianal skin lesions e.g. in Paget disease or Bowen disease, ... Using a bidigital technique (one finger in the anus and another in the vagina), the mass of the enterocele can be felt to "slip ... This reflex can be affected by Hirschsprung disease, Chagas disease, and hereditary myopathy of the internal anal sphincter. ... Rectal digitation is when patients insert a finger into the anus to "hook" out fecal pellets, or to apply pressure to the walls ...
913-915 Diseases affecting the rectum and anus are extremely common, especially in older adults. Hemorrhoids, vascular ... Gastrointestinal diseases (abbrev. GI diseases or GI illnesses) refer to diseases involving the gastrointestinal tract, namely ... Other causes of chronic liver disease are genetic or autoimmune disease, such as hemochromatosis, Wilson's disease, autoimmune ... Liver disease may also be a result of lifestyle factors, such as fatty liver and NASH. Alcoholic liver disease may also develop ...
Diseases of the Colon and their Surgical Treatment. John Wright & Sons, Bristol, 1910. Diseases of the Rectum and Anus: A ... He won the Jacksonian Prize for 1909 for his essay on diseases of the colon, which he published in 1910 as Diseases of the ... Diseases of the Rectum and Colon and their Surgical Treatment. Baillière, Tindall & Cox, London, 1923. (2nd edition 1934) The ... He showed that sigmoidoscopy was safe and effective in looking for diseases of the large bowel. During the First World War he ...
However, there is always the possibility of disease relapse, as Crohn's can affect mouth to anus. Since the late 1970s an ... Diseases of the large intestine which may require surgical removal include Crohn's disease, ulcerative colitis, familial ... In some patients with Crohn's disease, a procedure called an ileoanal anastomosis is done if the disease affects the entire ... 2003), "Surgery for inflammatory bowel diseases", Dig. Dis. 21(2):168-79. doi:10.3748/wjg.14.2678 "Colorectal Diseases and ...
Bowel control is often a challenge for children who are born with anomalies in their anus or rectum, Hirschsprung's disease, ... Children who have fecal incontinence after the repair of an imperforate anus are usually those born with a bad prognosis type ... An alteration of the muscles that surround the anorectal canal along with poor sphincters (the muscles that control the anus) ... Some patients operated on for Hirschsprung's disease have this anatomic problem as do those with spinal problems. The supply of ...
Crohn disease can affect any part of gastrointestinal tract, from mouth to anus. When it involves the mouth alone, some authors ... Zbar, AP; Ben-Horin, S; Beer-Gabel, M; Eliakim, R (March 2012). "Oral Crohn's disease: is it a separable disease from orofacial ... The disease usually presents in adolescence or young adulthood. It may occur in either sex, but males are slightly more ... The disease is characterized by non-caseating granulomatous inflammation. That is, the granulomas do not undergo the caseating ...
To prevent diseases of the anus[citation needed] and to promote general hygiene, humans often clean the exterior of the anus ... It is most often due to long-term exposure of the anus to faeces, with reasons including diseases of the anus such as ... The anus passes through the pelvic floor. The anus is surrounded by muscles. The top and bottom of the anus are surrounded by ... In humans, the anus (PL: anuses or ani; from Latin ānus, "ring", "circle") is the external opening of the rectum, located ...
Ball became a specialist in rectal diseases, writing The rectum and anus: their diseases and treatment (1887, 2nd ed. 1894) and ... Amongst his patients was John Millington Synge, who suffered from Hodgkin's disease. ... The rectum: its diseases and developmental effects (1908). He also contributed to journals and the Rectum article in F. ...
Hirschsprung's disease; gastric reflux, imperforate anus, retention testis, ectopic kidney, renal agenesis, and hydronephrosis ... Because of the rarity of the disease in addition to the variations in the disease, the specific genes that cause this disease ... 13q deletion syndrome is a rare genetic disease caused by the deletion of some or all of the large arm of human chromosome 13. ... This disease is also known as: 13q- Syndrome, Partial, Deletion 13q Syndrome, Partial Monosomy 13q, Partial Partial Monosomy of ...
... diverticulum 751.1 Congenital atresia and stenosis of small intestine 751.2 Imperforate anus 751.3 Hirschsprung's disease 751.4 ... 753 Congenital anomalies of urinary system 753.0 Renal agenesis and dysgenesis 753.1 Cystic kidney disease 753.2 Obstructive ...
Other congenital problems can include duodenal atresia, imperforate anus and gastroesophageal reflux disease.Celiac disease ... Many (15%) who live 40 years or longer develop Alzheimer's disease. In those who reach 60 years of age, 50-70% have the disease ... The rate of congenital heart disease in newborns with Down syndrome is around 40%. Of those with heart disease, about 80% have ... Hammer, Gary D. (2010). "Pathophysiology of Selected Genetic Diseases". In McPhee, Stephen J. (ed.). Pathophysiology of disease ...
... prompting other bacteria to adhere around the anus, causing skin disease (inflammation) around the anus. Some proctologists in ... It has two settings: one for washing the anus and one for the bidet function. The former is called posterior wash, general use ... The user can select to wash the anus or vulva by pressing the corresponding button on the control panel. Usually the same ... By default, the vulva receives less pressure than the anus. Researchers in Japan have found that most users prefer a water ...
The disease causes constipation because the inappropriate positioning of the anus which make it difficult to pass a bowel ... Imperforate anus is an anus that ends in a blind pouch and does not connect to the rest of the person's intestines. Small left ... A number of diseases present at birth can result in constipation. They are as a group uncommon with Hirschsprung's disease (HD ... imperforate anus, strictures, and small left colon syndrome. Anterior displacement of the anus can be diagnosed on physical ...
Viso, L.; Uriach, J. (October 1995). "The 'Guardians of the anus' and their practice". International Journal of Colorectal ... 10686, British Museum) also contains some recipes dealing with anorectal diseases." List of ancient Egyptian papyri Marry, ... December 1965). "The Chester Beatty Medical Papyrus: the earliest known treatise completely devoted to anorectal diseases". ... Diseases of the Colon & Rectum. 17 (1): 21-37. doi:10.1007/BF02587532. ...
1880 On Diseases of the Rectum and Anus - 1884 The Passage of Air and Faeces from the Urethra - 1888 Ovariotomy and Abdominal ... Diseases of the Colon & Rectum 1986; 29: p. 534-541 "William Harrison Cripps, F.R.C.S.", British Medical Journal, November 17, ... in the journal Diseases of the Colon & Rectum. In a contribution appended to Cripps' obituary in the British Medical Journal, ...
... and to whose book Pirrie's Surgery he contributed an article on diseases of the rectum and anus, a specialist subject of ...
... rectal diseases MeSH C06.405.469.860.101 - anus diseases MeSH C06.405.469.860.101.163 - anus neoplasms MeSH C06.405.469.860. ... hirschsprung disease MeSH C06.405.469.158.701.591 - megacolon, toxic MeSH C06.405.469.158.850 - sigmoid diseases MeSH C06.405. ... inflammatory bowel diseases MeSH C06.405.205.731.249 - colitis, ulcerative MeSH C06.405.205.731.500 - crohn disease MeSH ... inflammatory bowel diseases MeSH C06.405.469.432.249 - colitis, ulcerative MeSH C06.405.469.432.500 - crohn disease MeSH ...
"Omphalocele, exstrophy of the cloaca, imperforate anus, and spinal defects complex". Genetic and Rare Diseases Information ... It often causes the splitting of the bladder, genitalia, and the anus. It is sometimes called OEIS complex. Diagnostic tests ... and the International Classification of Diseases". Health and Human Rights. 20 (2): 205-214. PMC 6293350. PMID 30568414. ...
They are characterized by draining tracts in the skin around the anus. The cause is unknown. Surgical treatment is common, but ... This list of dog diseases is a selection of diseases and other conditions found in the dog. Some of these diseases are unique ... The disease in dogs is usually nodular skin lesions of the head and trunk. Aspergillosis* is a fungal disease that in dogs is ... Lyme disease* is a disease caused by Borrelia burgdorferi, a spirochaete, and spread by ticks of the genus Ixodes. Symptoms in ...
Previously, anal cancer was treated with surgery, and in early-stage disease (i.e., localised cancer of the anus without ... Symptoms may include bleeding from the anus or a lump near the anus. Other symptoms may include pain, itchiness, or discharge ... Gunderson et al., Anal Carcinoma: Impact of TN Category of Disease on Survival, Disease Relapse, and Colostomy Failure in US ... Anus, Gastrointestinal cancer, Papillomavirus-associated diseases, Infectious causes of cancer, Wikipedia medicine articles ...
Proctitis may also be caused by some types of inflammatory bowel disease, radiation therapy, injury to the rectum or anus, or ... "Crohn's Disease". The Lecturio Medical Concept Library. 28 August 2020. Retrieved 3 October 2021. "Crohn's disease". NHS UK. 23 ... Rare neoplasms at this site that can give rise to discharge include Paget's disease (which is possibly a type of adenocarcinoma ... Klas, JV; Rothenberger, DA; Wong, WD; Madoff, RD (Apr 15, 1999). "Malignant tumors of the anal canal: the spectrum of disease, ...
... hereditary Ochronosis Ockelbo disease Ocular albinism Ocular coloboma-imperforate anus Ocular convergence spasm Ocular ... This is a list of diseases starting with the letter "O". Diseases Alphabetical list 0-9 A B C D E F G H I J K L M N O P Q R S T ... autosomal recessive Optic atrophy Optic disc drusen Optic nerve coloboma with renal disease Optic nerve disorder Optic nerve ... Omodysplasia type 1 Omodysplasia type 2 Omphalocele cleft palate syndrome lethal Omphalocele exstrophy imperforate anus ...

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