I'm sorry for any confusion, but "Nicaragua" is not a medical term and does not have a medical definition. Nicaragua is the largest country in the Central American isthmus, bordering Honduras to the north and Costa Rica to the south. It has both Atlantic and Pacific coasts. The term you might be looking for is "Nicotine," which is a highly addictive stimulant found in tobacco leaves and is used as an ingredient in various products, including cigarettes, smokeless tobacco, and some medications.

Central America is not a medical term, but a geographical region consisting of seven countries (Belize, Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica, and Panama) that connect North America to South America, which may be relevant in medical contexts such as discussions of regional disease patterns, public health initiatives, or tropical medicine.